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Overview

ID MAG03376
Name SHD2_bin.20
Sample SMP0083
Taxonomy
Kingdom Bacteria
Phylum Eisenbacteria
Class RBG-16-71-46
Order JABDJR01
Family JAWXBZ01
Genus
Species
Assembly information
Completeness (%) 80.03
Contamination (%) 2.77
GC content (%) 67.0
N50 (bp) 4,139
Genome size (bp) 2,867,549

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2504

Gene name Description KEGG GOs EC E-value Score Sequence
SHD2_k127_100603_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 634.0
SHD2_k127_100603_1 alanine dehydrogenase activity K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 328.0
SHD2_k127_100603_2 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000000001155 79.0
SHD2_k127_1015444_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 332.0
SHD2_k127_1015444_1 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000002325 163.0
SHD2_k127_1015444_2 PTS system sorbose subfamily IIB component K02794,K19507 - 2.7.1.191 0.000000000000000000000000001288 124.0
SHD2_k127_1015444_3 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00002976 56.0
SHD2_k127_1067105_0 Cation transport regulator - - - 0.0000000003406 62.0
SHD2_k127_1069832_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000001541 213.0
SHD2_k127_1069832_1 COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.0000000000000000000000000000000000000001669 156.0
SHD2_k127_1069840_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004496 259.0
SHD2_k127_1069840_1 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000001995 162.0
SHD2_k127_1069840_2 COG2208 Serine phosphatase RsbU regulator of sigma subunit - - - 0.000000000000000000000000000000000000000005266 161.0
SHD2_k127_1075460_0 Formiminotransferase-cyclodeaminase K01746 - 4.3.1.4 0.0000000000000000000000000000000001834 140.0
SHD2_k127_1075460_1 Tetratricopeptide repeats - - - 0.00002033 57.0
SHD2_k127_1086586_0 5'-nucleotidase - - - 0.000000000000000000000000000007139 134.0
SHD2_k127_1086586_1 nucleotide catabolic process - - - 0.0000000000000000000000000001359 129.0
SHD2_k127_1086764_0 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002667 277.0
SHD2_k127_1086764_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000002415 213.0
SHD2_k127_1092809_0 PFAM NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 405.0
SHD2_k127_1092809_1 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000000000000000000000000000000000000000000000001169 233.0
SHD2_k127_1092809_2 Domain of unknown function (DUF1972) K12996 - - 0.0000000000000000000000000000000000000000001934 167.0
SHD2_k127_1092809_3 extracellular polysaccharide biosynthetic process K01153,K05789,K07011,K16554 - 3.1.21.3 0.0000000000000000000000000000001365 139.0
SHD2_k127_1092809_4 PEP-CTERM exosortase 1-associated glycosyltransferase, Daro_2409 family protein - - - 0.00000000000000000000167 111.0
SHD2_k127_1092825_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0005937 52.0
SHD2_k127_1093020_0 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.000000000000000000000002302 119.0
SHD2_k127_1093020_1 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000008441 99.0
SHD2_k127_1093020_2 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0005464 46.0
SHD2_k127_1098775_0 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 434.0
SHD2_k127_1098775_1 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000003424 160.0
SHD2_k127_1098775_2 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000000000002473 137.0
SHD2_k127_1098775_3 HAD-hyrolase-like K01560 - 3.8.1.2 0.0000817 47.0
SHD2_k127_1102603_0 type VI secretion protein K11900 - - 0.0000000000000000000000000000001433 141.0
SHD2_k127_1103857_1 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 503.0
SHD2_k127_1103857_2 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000002782 161.0
SHD2_k127_1110156_0 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 350.0
SHD2_k127_1110156_1 DoxX K15977 - - 0.000000000000000000000000000005433 123.0
SHD2_k127_1110156_2 - - - - 0.0000000000000000001208 97.0
SHD2_k127_11116_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.45e-239 758.0
SHD2_k127_11116_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 559.0
SHD2_k127_11116_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 417.0
SHD2_k127_11116_3 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 378.0
SHD2_k127_11116_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 306.0
SHD2_k127_11116_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 295.0
SHD2_k127_11116_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000727 192.0
SHD2_k127_1117857_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 583.0
SHD2_k127_1117857_1 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 293.0
SHD2_k127_1117857_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000003717 239.0
SHD2_k127_1117857_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000001387 57.0
SHD2_k127_1117857_4 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000003571 52.0
SHD2_k127_1117984_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 363.0
SHD2_k127_1117984_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 324.0
SHD2_k127_1117984_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001678 264.0
SHD2_k127_1117984_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000329 212.0
SHD2_k127_1117984_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000001179 188.0
SHD2_k127_1117984_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000001919 179.0
SHD2_k127_1117984_6 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000000000000006358 192.0
SHD2_k127_1117984_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000000002576 140.0
SHD2_k127_1117984_8 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000003161 137.0
SHD2_k127_1117984_9 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000005159 70.0
SHD2_k127_1118565_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 572.0
SHD2_k127_1118565_1 - - - - 0.000000000000000000000000000001294 124.0
SHD2_k127_1118565_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000001209 113.0
SHD2_k127_1118565_3 Hsp20/alpha crystallin family - - - 0.00000000000000000455 90.0
SHD2_k127_1122904_0 Tricorn protease homolog K08676 - - 1.691e-305 975.0
SHD2_k127_1122904_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 464.0
SHD2_k127_1122904_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 386.0
SHD2_k127_1122904_3 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000004776 106.0
SHD2_k127_1122904_4 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000001696 50.0
SHD2_k127_112997_0 Aconitase C-terminal domain - - - 1.886e-249 792.0
SHD2_k127_112997_1 Protein of unknown function (DUF2723) - - - 0.00000000000000000000000000000000000000000000000000000005067 217.0
SHD2_k127_112997_2 anaphase-promoting complex binding - - - 0.0006469 52.0
SHD2_k127_1138868_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 430.0
SHD2_k127_1138868_1 - - - - 0.00000001096 67.0
SHD2_k127_1143076_0 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 8.175e-210 661.0
SHD2_k127_1143076_1 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000005548 168.0
SHD2_k127_1143076_2 Transcriptional regulator - - - 0.0000000000000000000000000000000006389 143.0
SHD2_k127_1144448_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 404.0
SHD2_k127_1144448_1 Collagenase NC10 and Endostatin K06823,K08135 GO:0000902,GO:0000904,GO:0001764,GO:0003008,GO:0003012,GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005581,GO:0005604,GO:0006928,GO:0006935,GO:0006996,GO:0007005,GO:0007154,GO:0007267,GO:0007268,GO:0007271,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0008045,GO:0008104,GO:0008150,GO:0009605,GO:0009653,GO:0009966,GO:0009967,GO:0009987,GO:0010646,GO:0010647,GO:0014732,GO:0014887,GO:0014888,GO:0014889,GO:0014891,GO:0014899,GO:0016043,GO:0016477,GO:0022008,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030054,GO:0030154,GO:0030182,GO:0030198,GO:0030246,GO:0031012,GO:0031175,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0035418,GO:0040011,GO:0040039,GO:0042221,GO:0042330,GO:0043062,GO:0043500,GO:0043501,GO:0044421,GO:0048468,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050789,GO:0050794,GO:0050808,GO:0050896,GO:0051179,GO:0051674,GO:0061564,GO:0062023,GO:0065007,GO:0071711,GO:0071840,GO:0097485,GO:0098916,GO:0099536,GO:0099537,GO:0120036,GO:0120039,GO:2001044,GO:2001046 - 0.000009667 55.0
SHD2_k127_114491_0 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 385.0
SHD2_k127_114491_1 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000007518 169.0
SHD2_k127_1147944_0 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 467.0
SHD2_k127_1147944_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000006229 151.0
SHD2_k127_1147944_2 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000004612 108.0
SHD2_k127_1149829_0 Major facilitator Superfamily K08162,K08226,K16211 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 500.0
SHD2_k127_1149829_1 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000002433 247.0
SHD2_k127_1149829_2 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain III, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II, Phosphoglucomutase phosphomannomutase, C-terminal domain, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain I K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000001474 188.0
SHD2_k127_1149829_3 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000001328 192.0
SHD2_k127_1149829_4 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000001286 138.0
SHD2_k127_1149829_5 DinB superfamily - - - 0.00000000000000000000000000001473 123.0
SHD2_k127_1149829_6 - - - - 0.00000000000000289 85.0
SHD2_k127_1157390_0 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 419.0
SHD2_k127_1162039_0 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000001671 218.0
SHD2_k127_1162039_1 - - - - 0.000000001545 65.0
SHD2_k127_1167370_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000001958 250.0
SHD2_k127_1167370_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000001432 185.0
SHD2_k127_117942_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 327.0
SHD2_k127_118197_0 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 467.0
SHD2_k127_118197_1 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000005642 146.0
SHD2_k127_118197_2 Integral membrane protein TerC family K05794 - - 0.0000000000000000000006961 96.0
SHD2_k127_1183935_0 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 532.0
SHD2_k127_1183935_1 FliG N-terminal domain K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008148 263.0
SHD2_k127_1183935_2 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000004327 250.0
SHD2_k127_1183935_3 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000002713 111.0
SHD2_k127_1183935_4 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000001616 85.0
SHD2_k127_1183935_5 Flagellar assembly protein FliH K02411 - - 0.0000000000003724 80.0
SHD2_k127_1184180_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 374.0
SHD2_k127_1184180_1 NUDIX domain K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003338 269.0
SHD2_k127_1190819_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 439.0
SHD2_k127_1190819_1 Domains REC, sigma54 interaction, HTH8 K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 420.0
SHD2_k127_1190819_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 415.0
SHD2_k127_1190819_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000001372 229.0
SHD2_k127_1190819_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000008561 106.0
SHD2_k127_1199951_0 purine nucleobase transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 324.0
SHD2_k127_1199951_1 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000003824 94.0
SHD2_k127_1199951_2 MerR HTH family regulatory protein - - - 0.0000000000000001616 86.0
SHD2_k127_121853_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 353.0
SHD2_k127_121853_1 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001136 252.0
SHD2_k127_121853_2 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000102 199.0
SHD2_k127_121853_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000007899 172.0
SHD2_k127_1234379_0 peptide deformylase activity - - - 0.0000000000000000000000000000000000000000000000003506 185.0
SHD2_k127_1236922_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 468.0
SHD2_k127_1236922_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003335 296.0
SHD2_k127_1236922_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009309 271.0
SHD2_k127_1236922_3 MlaD protein K02067 - - 0.00000000000000000004788 102.0
SHD2_k127_1236922_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000391 67.0
SHD2_k127_1241629_0 PFAM Aminotransferase class I and II K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 447.0
SHD2_k127_1241629_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 441.0
SHD2_k127_1241629_2 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006213 279.0
SHD2_k127_1241629_3 protein secretion K09800 - - 0.0000000000001426 85.0
SHD2_k127_1241629_4 G-protein signalling modulator 2 (AGS3-like, C. elegans) K15837,K15839 GO:0000132,GO:0000226,GO:0000278,GO:0000922,GO:0001709,GO:0001965,GO:0003674,GO:0005092,GO:0005096,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0005938,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007154,GO:0007163,GO:0007165,GO:0007186,GO:0007264,GO:0007265,GO:0007275,GO:0007346,GO:0007399,GO:0007400,GO:0007405,GO:0008022,GO:0008047,GO:0008104,GO:0008150,GO:0008283,GO:0008356,GO:0009987,GO:0010564,GO:0010638,GO:0014016,GO:0014017,GO:0015630,GO:0016020,GO:0016043,GO:0017145,GO:0019904,GO:0022008,GO:0022402,GO:0023052,GO:0030010,GO:0030154,GO:0030234,GO:0030695,GO:0031291,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0035556,GO:0036445,GO:0040001,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043547,GO:0043621,GO:0044087,GO:0044089,GO:0044093,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0044877,GO:0045165,GO:0045167,GO:0045175,GO:0045177,GO:0045179,GO:0045185,GO:0045787,GO:0048103,GO:0048518,GO:0048522,GO:0048699,GO:0048731,GO:0048856,GO:0048863,GO:0048865,GO:0048867,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050795,GO:0050896,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051235,GO:0051293,GO:0051294,GO:0051301,GO:0051336,GO:0051345,GO:0051493,GO:0051495,GO:0051640,GO:0051641,GO:0051642,GO:0051649,GO:0051651,GO:0051653,GO:0051656,GO:0051657,GO:0051661,GO:0051716,GO:0051726,GO:0055057,GO:0055059,GO:0060236,GO:0060259,GO:0060341,GO:0060589,GO:0061351,GO:0061842,GO:0065007,GO:0065008,GO:0065009,GO:0070507,GO:0070840,GO:0071840,GO:0071944,GO:0072089,GO:0072686,GO:0090068,GO:0090169,GO:0090224,GO:0097431,GO:0097574,GO:0097575,GO:0098722,GO:0098772,GO:0099568,GO:0099738,GO:1902115,GO:1902117,GO:1902850,GO:1903047,GO:1903827,GO:1903829,GO:1904375,GO:1904377,GO:1904776,GO:1904778,GO:1905832 - 0.0000000000002516 81.0
SHD2_k127_124806_0 PFAM PHP domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000002104 244.0
SHD2_k127_124806_1 Tetratricopeptide repeat - - - 0.0000000000000007972 87.0
SHD2_k127_1253118_0 Tricorn protease homolog K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 571.0
SHD2_k127_1263210_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 306.0
SHD2_k127_1263210_1 transcription factor binding K02584,K11914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 320.0
SHD2_k127_1263210_2 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001139 222.0
SHD2_k127_1263210_3 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000002612 162.0
SHD2_k127_1263210_4 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000007794 115.0
SHD2_k127_1263210_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000001202 65.0
SHD2_k127_1266622_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 333.0
SHD2_k127_1266622_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000002253 127.0
SHD2_k127_127727_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 309.0
SHD2_k127_127727_1 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006511 235.0
SHD2_k127_127727_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000008839 193.0
SHD2_k127_127727_3 AntiSigma factor - - - 0.0000000009961 64.0
SHD2_k127_1278970_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000002541 138.0
SHD2_k127_1278970_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000002155 125.0
SHD2_k127_1278970_2 TonB C terminal K03646,K03832 - - 0.000000000001609 79.0
SHD2_k127_1278970_3 Protein of unknown function (DUF507) - - - 0.00000002368 61.0
SHD2_k127_1278970_4 Preprotein translocase subunit SecG K03075 - - 0.00000003319 61.0
SHD2_k127_1278970_5 Protein of unknown function (DUF507) - - - 0.00003042 50.0
SHD2_k127_1282466_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 532.0
SHD2_k127_1282466_1 PFAM Alpha amylase, catalytic K01176 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000008652 273.0
SHD2_k127_1282466_2 Metalloenzyme superfamily - - - 0.00000000000000000000000000000000000000000000000000000005469 209.0
SHD2_k127_1282466_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000004081 113.0
SHD2_k127_1292751_0 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 349.0
SHD2_k127_1292751_1 TPR Domain containing protein K12600 - - 0.00000000000000009744 95.0
SHD2_k127_1292751_2 COG0457 FOG TPR repeat - - - 0.000000000000002068 91.0
SHD2_k127_1292751_3 hmm pf07719 - - - 0.00000009268 62.0
SHD2_k127_1297242_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 430.0
SHD2_k127_1297242_1 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000001119 140.0
SHD2_k127_1297242_2 XdhC and CoxI family K07402 - - 0.00000000000861 66.0
SHD2_k127_1297856_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 395.0
SHD2_k127_1297856_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000003892 174.0
SHD2_k127_1297856_2 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0000000000000000000000000000000000001507 142.0
SHD2_k127_1297856_3 - - - - 0.000000000000000000001233 103.0
SHD2_k127_1297856_4 peptidase activity, acting on L-amino acid peptides - - - 0.0000000002518 74.0
SHD2_k127_130021_0 PFAM Type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 316.0
SHD2_k127_130021_1 Secretin and TonB N terminus short domain K02453,K02507,K02666 - - 0.0000000000000000000000000000000000000000000000000000001004 211.0
SHD2_k127_1302409_0 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 341.0
SHD2_k127_1302409_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000008521 180.0
SHD2_k127_1302950_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 372.0
SHD2_k127_1302950_1 4Fe-4S binding domain K08358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 331.0
SHD2_k127_1302950_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003019 266.0
SHD2_k127_1302950_3 - - - - 0.0000000000001305 71.0
SHD2_k127_1305530_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 447.0
SHD2_k127_1305530_1 Glycosyltransferase family 87 - - - 0.0000000000000000000000000000000000000001693 168.0
SHD2_k127_1305530_2 - - - - 0.000000000000000003172 96.0
SHD2_k127_1305530_3 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000001047 80.0
SHD2_k127_1305530_4 Exopolysaccharide biosynthesis protein YbjH - - - 0.0000000002315 70.0
SHD2_k127_130603_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008876 566.0
SHD2_k127_130603_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 443.0
SHD2_k127_130603_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 304.0
SHD2_k127_13061_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 613.0
SHD2_k127_13061_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 367.0
SHD2_k127_13061_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 362.0
SHD2_k127_13061_3 - - - - 0.000000000000000000000000000000000001041 144.0
SHD2_k127_13061_4 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000000000000000000000000003854 155.0
SHD2_k127_13061_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000004257 148.0
SHD2_k127_13061_6 - - - - 0.0000000000000000000000000000005412 135.0
SHD2_k127_13061_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000002971 76.0
SHD2_k127_13061_8 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000011 67.0
SHD2_k127_13061_9 BA14K-like protein - - - 0.00003322 54.0
SHD2_k127_1315990_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 492.0
SHD2_k127_1315990_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 392.0
SHD2_k127_1315990_2 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000002462 156.0
SHD2_k127_1337255_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 308.0
SHD2_k127_1337255_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000002938 141.0
SHD2_k127_1338565_0 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 412.0
SHD2_k127_1338565_1 Tetratricopeptide repeat - - - 0.0000000000002419 78.0
SHD2_k127_134134_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000006149 176.0
SHD2_k127_134134_1 DivIVA protein K04074 - - 0.00000000000000003238 84.0
SHD2_k127_134134_2 Beta-propeller repeat - - - 0.000000009957 68.0
SHD2_k127_1341510_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1018.0
SHD2_k127_1341510_1 Protein conserved in bacteria - - - 0.0009174 44.0
SHD2_k127_1354349_0 Extradiol ring-cleavage dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 366.0
SHD2_k127_1354349_1 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001196 275.0
SHD2_k127_135594_0 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004805 287.0
SHD2_k127_135594_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000008506 237.0
SHD2_k127_135594_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000008567 123.0
SHD2_k127_135594_3 - - - - 0.000001385 61.0
SHD2_k127_1358728_0 Transcriptional regulator, Fis family - - - 3.728e-203 647.0
SHD2_k127_1358728_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004273 241.0
SHD2_k127_1358728_10 PFAM OmpA MotB domain protein K03640 - - 0.00005475 52.0
SHD2_k127_1358728_11 - - - - 0.0003054 47.0
SHD2_k127_1358728_2 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000009863 223.0
SHD2_k127_1358728_4 - - - - 0.0000000000000000000002835 100.0
SHD2_k127_1358728_5 Periplasmic or secreted lipoprotein - - - 0.000000000000000003191 95.0
SHD2_k127_1358728_6 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000003698 77.0
SHD2_k127_1358728_7 - - - - 0.000000000000006146 78.0
SHD2_k127_1358728_8 - - - - 0.0000000000002101 79.0
SHD2_k127_1358728_9 Membrane - - - 0.00001281 55.0
SHD2_k127_1360166_0 Chemotaxis protein methyltransferase K00575 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006479,GO:0006807,GO:0006935,GO:0008022,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0008983,GO:0009605,GO:0009987,GO:0010340,GO:0016020,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0032991,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051998,GO:0071704,GO:0071944,GO:0098561,GO:0140096,GO:1901564 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000006616 217.0
SHD2_k127_1360166_1 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000003197 179.0
SHD2_k127_1360166_2 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000004959 132.0
SHD2_k127_1363716_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 441.0
SHD2_k127_1363716_1 KaiC K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 430.0
SHD2_k127_1363716_2 PFAM MscS Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000009365 246.0
SHD2_k127_1363716_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000152 251.0
SHD2_k127_1363716_4 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000188 194.0
SHD2_k127_1363716_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576 2.7.7.60,4.6.1.12 0.00000000000000000000000000000002167 137.0
SHD2_k127_1368306_0 Aldo/keto reductase family K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 405.0
SHD2_k127_1368306_1 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 374.0
SHD2_k127_1368306_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000004691 266.0
SHD2_k127_1368306_3 - - - - 0.00000000000000000000000000000000000000000000000008662 192.0
SHD2_k127_1370766_0 DNA-templated transcription, initiation K03088 - - 0.0000000000000006551 82.0
SHD2_k127_1375109_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 485.0
SHD2_k127_1384703_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1165.0
SHD2_k127_1384703_1 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002963 253.0
SHD2_k127_1384703_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K00587 - 2.1.1.100 0.000000000000000000000000000000000006692 143.0
SHD2_k127_1384703_3 Aldo/keto reductase family K05882 - 1.1.1.91 0.0000000000000000005752 87.0
SHD2_k127_1384703_4 STAS domain K04749 - - 0.00004449 52.0
SHD2_k127_1414152_0 PFAM glycoside hydrolase family 13 domain protein - - - 0.00000000000000001095 90.0
SHD2_k127_1414152_1 - - - - 0.000006343 58.0
SHD2_k127_141561_0 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 344.0
SHD2_k127_141882_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 443.0
SHD2_k127_141882_1 thiolester hydrolase activity K06889 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 - 0.00000000000000000000000000000000000000000000000000001228 201.0
SHD2_k127_141882_2 - - - - 0.00000000000000000000002288 114.0
SHD2_k127_1428216_0 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 463.0
SHD2_k127_1428216_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 422.0
SHD2_k127_1428216_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000001436 187.0
SHD2_k127_144541_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001026 257.0
SHD2_k127_144541_1 Multicopper oxidase K04753 - - 0.000000000000000000000000000000000000000000004762 189.0
SHD2_k127_144541_2 protein secretion K09800 - - 0.00000003779 68.0
SHD2_k127_1470654_0 threonyl-tRNA aminoacylation K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.087e-244 772.0
SHD2_k127_1470654_1 Ferredoxin-fold anticodon binding domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 393.0
SHD2_k127_1470654_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 370.0
SHD2_k127_1470654_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.000000000000000000000000000000000000000000000000000001559 201.0
SHD2_k127_1470654_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000465 139.0
SHD2_k127_1470654_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000001768 75.0
SHD2_k127_1481552_0 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000006561 141.0
SHD2_k127_1481552_1 Chalcone isomerase-like - - - 0.00000000174 70.0
SHD2_k127_1481552_2 Domain of unknown function (DUF4386) - - - 0.0002798 45.0
SHD2_k127_1499038_0 Sialate O-acetylesterase K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 357.0
SHD2_k127_1499038_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 307.0
SHD2_k127_1499038_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000008168 124.0
SHD2_k127_1518440_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 383.0
SHD2_k127_1518440_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000005733 135.0
SHD2_k127_1518440_2 PFAM Uncharacterised BCR, COG1649 - - - 0.00005899 51.0
SHD2_k127_1520484_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 336.0
SHD2_k127_1520484_1 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000004635 229.0
SHD2_k127_1520484_2 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000659 191.0
SHD2_k127_1520484_3 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000003252 113.0
SHD2_k127_1520484_4 TIGRFAM anti-anti-sigma factor - - - 0.000000003923 66.0
SHD2_k127_1526579_0 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004299 259.0
SHD2_k127_1526579_1 COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase - - - 0.00000000003769 72.0
SHD2_k127_1526579_2 FAD dependent oxidoreductase - - - 0.0000000004433 69.0
SHD2_k127_1538168_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 477.0
SHD2_k127_1538877_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 417.0
SHD2_k127_1538877_1 Conserved TM helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 316.0
SHD2_k127_1538877_2 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000006119 233.0
SHD2_k127_1546897_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 0.0 1197.0
SHD2_k127_1546897_1 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 317.0
SHD2_k127_1546897_2 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000004466 210.0
SHD2_k127_1546897_3 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.0000000000000000000000000000000000000000000000002169 183.0
SHD2_k127_1551460_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 410.0
SHD2_k127_1551460_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 331.0
SHD2_k127_1551460_2 Low affinity iron permease - - - 0.00000000000000000000000000000000000000001372 155.0
SHD2_k127_1551460_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000003464 148.0
SHD2_k127_1551460_4 helix_turn_helix, mercury resistance K19591,K22491 - - 0.0000000000000000001638 98.0
SHD2_k127_1557430_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 488.0
SHD2_k127_1557430_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 392.0
SHD2_k127_1557430_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000002394 177.0
SHD2_k127_1557430_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000007914 144.0
SHD2_k127_1557430_4 Ethylbenzene dehydrogenase - - - 0.0002351 53.0
SHD2_k127_157125_0 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006441 245.0
SHD2_k127_157125_1 glycosyl transferase family - - - 0.00000000000000000001314 106.0
SHD2_k127_1600314_0 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000002549 175.0
SHD2_k127_1600314_1 FAD binding domain K00103,K00279 - 1.1.3.8,1.5.99.12 0.00000000000000000000002916 104.0
SHD2_k127_1602732_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000003883 113.0
SHD2_k127_160767_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.071e-198 631.0
SHD2_k127_160767_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000001441 154.0
SHD2_k127_160767_2 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000004844 126.0
SHD2_k127_160767_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000004863 107.0
SHD2_k127_1608310_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 385.0
SHD2_k127_1608310_1 Transporter associated domain - - - 0.000000000000000000000000000000000000000002609 179.0
SHD2_k127_1608310_2 CBS domain K03699 - - 0.0000000000000000000000000000000613 139.0
SHD2_k127_1608310_3 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000004502 132.0
SHD2_k127_1608310_4 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000002137 125.0
SHD2_k127_1612947_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 585.0
SHD2_k127_1612947_1 PFAM Enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000611 217.0
SHD2_k127_1612947_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000001036 75.0
SHD2_k127_1612947_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000008643 81.0
SHD2_k127_1627094_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 5.732e-289 904.0
SHD2_k127_1627094_1 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002535 282.0
SHD2_k127_1627094_2 - K03561,K12287 - - 0.00000000000000000000000000000000000000003345 177.0
SHD2_k127_1627094_3 Archaeal Type IV pilin, N-terminal - - - 0.000000006488 70.0
SHD2_k127_1627094_4 amine dehydrogenase activity K01406 - 3.4.24.40 0.0000006955 64.0
SHD2_k127_1650861_0 tRNA synthetases class II (D, K and N) K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 578.0
SHD2_k127_1650861_1 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000001264 163.0
SHD2_k127_1650861_2 heptosyltransferase K02843 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000102 128.0
SHD2_k127_1650861_3 PFAM outer membrane efflux protein - - - 0.00000000000000000000000004576 124.0
SHD2_k127_1650861_4 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000001281 106.0
SHD2_k127_1650861_5 heat shock protein binding - - - 0.0000000000000002654 90.0
SHD2_k127_1650861_6 Tetratricopeptide repeat - - - 0.0000000000001175 85.0
SHD2_k127_1693767_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 498.0
SHD2_k127_1693767_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 472.0
SHD2_k127_1693767_2 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000008649 187.0
SHD2_k127_1693767_3 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000001282 67.0
SHD2_k127_169562_0 Belongs to the ClpA ClpB family K11907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 491.0
SHD2_k127_169562_1 Phage late control gene D protein (GPD) K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 439.0
SHD2_k127_1704276_0 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000002269 95.0
SHD2_k127_170706_0 Amino acid kinase family K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 313.0
SHD2_k127_170706_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000026 210.0
SHD2_k127_170706_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000003379 186.0
SHD2_k127_170706_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000981 89.0
SHD2_k127_1720412_0 FlgD Ig-like domain K15924 - 3.2.1.136 0.000000000000009517 88.0
SHD2_k127_1720412_1 Evidence 5 No homology to any previously reported sequences - - - 0.0000000004566 69.0
SHD2_k127_173384_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 9.818e-270 845.0
SHD2_k127_17479_0 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000001283 143.0
SHD2_k127_17479_1 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000008972 122.0
SHD2_k127_17479_2 PFAM sigma-70 region 2 domain protein - - - 0.00000000000003419 79.0
SHD2_k127_1779494_0 Glycosyltransferase 36 associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 558.0
SHD2_k127_178877_0 Alpha-2-Macroglobulin K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 392.0
SHD2_k127_1792736_0 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 1.715e-281 869.0
SHD2_k127_1792736_1 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 377.0
SHD2_k127_1792736_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002545 268.0
SHD2_k127_1792736_3 Transcriptional regulator - - - 0.000000000000000000000000000000009094 134.0
SHD2_k127_1792736_4 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.00000000122 63.0
SHD2_k127_179849_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 499.0
SHD2_k127_179849_1 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000007789 183.0
SHD2_k127_179898_0 Alpha-glucan phosphorylase K00688 - 2.4.1.1 7.989e-276 862.0
SHD2_k127_179898_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 318.0
SHD2_k127_1826251_0 peptidase dimerisation domain protein - - - 0.0000000000000000000000000004604 115.0
SHD2_k127_1826251_1 membrane protein (DUF2079) - - - 0.000000000000413 83.0
SHD2_k127_183331_0 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 396.0
SHD2_k127_183331_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000002333 244.0
SHD2_k127_1854494_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 6.093e-262 823.0
SHD2_k127_1872026_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 519.0
SHD2_k127_1891008_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 315.0
SHD2_k127_1891008_1 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004702 286.0
SHD2_k127_1891008_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000008281 72.0
SHD2_k127_1891008_3 protein kinase activity K12132 - 2.7.11.1 0.00006219 47.0
SHD2_k127_1892287_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 2.237e-211 665.0
SHD2_k127_1892287_1 Belongs to the peptidase S8 family K14743 - - 0.0000000000000000000000000000000000000009464 165.0
SHD2_k127_1892287_2 CHAT domain - - - 0.000000000000000000000000000000001224 137.0
SHD2_k127_1892287_3 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.00000000000000000000000000001284 127.0
SHD2_k127_1892287_4 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000189 70.0
SHD2_k127_1895200_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 401.0
SHD2_k127_1895200_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000004455 256.0
SHD2_k127_1895200_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000242 65.0
SHD2_k127_190683_0 PFAM peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 384.0
SHD2_k127_190683_1 prohibitin homologues - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007443 269.0
SHD2_k127_190683_2 NfeD-like C-terminal, partner-binding K07403 - - 0.0000001764 57.0
SHD2_k127_190683_3 Two component regulator propeller - - - 0.0003194 52.0
SHD2_k127_1922205_0 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 372.0
SHD2_k127_1922205_1 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 342.0
SHD2_k127_1922205_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000001257 186.0
SHD2_k127_1925366_0 rRNA binding K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 389.0
SHD2_k127_1925366_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004151 280.0
SHD2_k127_1925366_10 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000006624 136.0
SHD2_k127_1925366_11 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000611 119.0
SHD2_k127_1925366_12 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000002592 119.0
SHD2_k127_1925366_13 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000003725 113.0
SHD2_k127_1925366_14 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000004989 99.0
SHD2_k127_1925366_15 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000003667 78.0
SHD2_k127_1925366_16 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000001164 64.0
SHD2_k127_1925366_17 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000006681 57.0
SHD2_k127_1925366_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002468 250.0
SHD2_k127_1925366_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000824 227.0
SHD2_k127_1925366_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000002155 223.0
SHD2_k127_1925366_5 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000006427 202.0
SHD2_k127_1925366_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000001992 178.0
SHD2_k127_1925366_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000008498 174.0
SHD2_k127_1925366_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000001017 158.0
SHD2_k127_1925366_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000002758 146.0
SHD2_k127_1947149_0 ABC transporter - - - 4.112e-258 806.0
SHD2_k127_1947149_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 301.0
SHD2_k127_1947149_2 PFAM Fatty acid desaturase K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000002792 216.0
SHD2_k127_1948344_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000006119 201.0
SHD2_k127_1962745_0 Short chain fatty acid transporter K02106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 442.0
SHD2_k127_1962745_1 PFAM Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 401.0
SHD2_k127_1982850_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 310.0
SHD2_k127_1991764_0 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000000002107 178.0
SHD2_k127_1991764_1 Tetratricopeptide repeat - - - 0.000001781 58.0
SHD2_k127_205002_0 Domain of unknown function (DUF4932) - - - 0.00002254 56.0
SHD2_k127_205002_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00008771 53.0
SHD2_k127_205002_2 Peptidase s1 and s6 chymotrypsin hap K08372 - - 0.000656 51.0
SHD2_k127_2056278_0 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 317.0
SHD2_k127_2056278_1 Coenzyme A transferase K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 291.0
SHD2_k127_2062232_0 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002416 248.0
SHD2_k127_2062232_1 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000005686 205.0
SHD2_k127_2062232_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000007614 195.0
SHD2_k127_2062232_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000003964 103.0
SHD2_k127_2062232_4 Ami_3 K01448 - 3.5.1.28 0.00000000000000356 89.0
SHD2_k127_206848_0 NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 355.0
SHD2_k127_206848_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000003479 156.0
SHD2_k127_206848_2 Polysaccharide deacetylase - - - 0.0000000000000001689 85.0
SHD2_k127_206848_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000008255 70.0
SHD2_k127_207660_0 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 304.0
SHD2_k127_207660_1 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000001705 184.0
SHD2_k127_207660_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000001249 172.0
SHD2_k127_2102654_0 protein conserved in bacteria K09927 - - 0.00000000000000000000000000000000000000000000000000000000221 224.0
SHD2_k127_2102654_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000001383 179.0
SHD2_k127_2102654_2 PFAM Fibronectin type III domain - - - 0.0000000000000006216 86.0
SHD2_k127_2120058_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 385.0
SHD2_k127_2120058_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 328.0
SHD2_k127_2120058_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000003937 259.0
SHD2_k127_2120058_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000005157 127.0
SHD2_k127_2121813_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.306e-241 774.0
SHD2_k127_2121813_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008893 274.0
SHD2_k127_2134851_0 DNA RNA non-specific endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000001283 255.0
SHD2_k127_2134851_1 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000001393 165.0
SHD2_k127_2134851_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000001004 78.0
SHD2_k127_2134851_3 - - - - 0.000008814 58.0
SHD2_k127_2134851_4 polysaccharide biosynthetic process K00721 - 2.4.1.83 0.0001157 47.0
SHD2_k127_2135485_0 Competence protein K02238 - - 0.000000000000000000000000000000000000000002124 178.0
SHD2_k127_2135485_1 Competence protein K02238 - - 0.000000000000000000000000000003093 130.0
SHD2_k127_2151267_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1102.0
SHD2_k127_2151267_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 389.0
SHD2_k127_2153391_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 406.0
SHD2_k127_2153391_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000861 232.0
SHD2_k127_2153391_2 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000005789 99.0
SHD2_k127_2153391_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000006916 54.0
SHD2_k127_2153391_4 glycosyl transferase family - - - 0.000008291 56.0
SHD2_k127_2161761_0 Arginosuccinate synthase K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 390.0
SHD2_k127_2161761_1 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 321.0
SHD2_k127_2161761_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000001111 223.0
SHD2_k127_2161761_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000001094 155.0
SHD2_k127_2161761_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000007518 105.0
SHD2_k127_2161761_5 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000002656 102.0
SHD2_k127_216247_0 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 285.0
SHD2_k127_216247_1 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000003278 242.0
SHD2_k127_2163128_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 299.0
SHD2_k127_2163128_1 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000009931 222.0
SHD2_k127_2163128_2 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000002447 198.0
SHD2_k127_2163128_3 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000005202 183.0
SHD2_k127_2163128_4 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000000002512 158.0
SHD2_k127_2163128_5 S4 RNA-binding domain - GO:0008150,GO:0040007 - 0.000000000000000002422 88.0
SHD2_k127_2163128_6 Subtilase family - - - 0.0000958 51.0
SHD2_k127_2168379_0 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 324.0
SHD2_k127_2168379_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 300.0
SHD2_k127_2168379_2 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002454 259.0
SHD2_k127_2168379_3 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005594 257.0
SHD2_k127_2168379_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000008305 221.0
SHD2_k127_2168379_5 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000001047 130.0
SHD2_k127_2168379_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000006065 139.0
SHD2_k127_2168379_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K05788 - - 0.0000000000000000000000000009188 115.0
SHD2_k127_2168379_8 protein conserved in bacteria - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.0000000005264 70.0
SHD2_k127_2168509_0 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 418.0
SHD2_k127_2168509_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000001793 224.0
SHD2_k127_2173084_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 4.526e-250 777.0
SHD2_k127_2174212_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.724e-276 865.0
SHD2_k127_2174212_1 DNA topoisomerase II activity K02469 - 5.99.1.3 1.977e-262 821.0
SHD2_k127_2174212_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 456.0
SHD2_k127_2174212_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 300.0
SHD2_k127_2174212_4 Ribosomal protein L34 K02914 - - 0.0000000000001071 73.0
SHD2_k127_2174212_5 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000000005909 65.0
SHD2_k127_2174212_6 Protein of unknown function (DUF721) - - - 0.00000008635 58.0
SHD2_k127_218088_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 376.0
SHD2_k127_2185427_0 transmembrane signaling receptor activity - - - 0.0000000000000000000000001537 112.0
SHD2_k127_2185427_1 FlgD Ig-like domain K15924 - 3.2.1.136 0.00000000005829 77.0
SHD2_k127_2185427_2 Matrix metallopeptidase 8 K01388,K01394,K01402,K07763,K07994,K07999 GO:0001503,GO:0001704,GO:0001706,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0007275,GO:0007369,GO:0007492,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0009056,GO:0009653,GO:0009790,GO:0009888,GO:0009987,GO:0012505,GO:0016043,GO:0016192,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022617,GO:0030141,GO:0030154,GO:0030198,GO:0030574,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032501,GO:0032502,GO:0032940,GO:0032963,GO:0034774,GO:0035580,GO:0035987,GO:0036230,GO:0042119,GO:0042581,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0043299,GO:0043312,GO:0044238,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0046914,GO:0048598,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070011,GO:0070013,GO:0070820,GO:0071704,GO:0071840,GO:0097708,GO:0099503,GO:0140096,GO:1901564,GO:1904724 3.4.24.17,3.4.24.34,3.4.24.7,3.4.24.80 0.0000000001011 76.0
SHD2_k127_218934_0 Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 384.0
SHD2_k127_218934_1 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000001712 213.0
SHD2_k127_218934_2 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.0000000000000000000000000000000000000000000000000000004365 201.0
SHD2_k127_218934_3 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000006488 161.0
SHD2_k127_218934_4 methylenetetrahydrofolate reductase (NAD(P)H) activity K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.0000000000000000000000000000000000001453 146.0
SHD2_k127_218934_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000013 115.0
SHD2_k127_2191308_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 467.0
SHD2_k127_2191308_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 379.0
SHD2_k127_2191308_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007897 253.0
SHD2_k127_2191308_3 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000003881 227.0
SHD2_k127_2191639_0 Large family of predicted nucleotide-binding domains K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 487.0
SHD2_k127_2191639_1 Peptidase M3A and M3B thimet oligopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 486.0
SHD2_k127_2191639_2 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000001757 185.0
SHD2_k127_2192458_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 473.0
SHD2_k127_2192458_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 450.0
SHD2_k127_2192458_2 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 425.0
SHD2_k127_2192458_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00004781 50.0
SHD2_k127_2195423_0 Evidence 5 No homology to any previously reported sequences - - - 0.000000002683 70.0
SHD2_k127_2196143_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 604.0
SHD2_k127_2196143_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000002997 217.0
SHD2_k127_2207749_0 electron transfer activity K00405,K02305,K08738,K17223 - - 0.00000000000000000000000000000000000001249 160.0
SHD2_k127_2229794_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005398 271.0
SHD2_k127_2229794_1 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000001293 160.0
SHD2_k127_2230937_0 pilus assembly protein K02662 - - 0.0009112 51.0
SHD2_k127_2233140_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000002731 128.0
SHD2_k127_2233140_1 Domain of unknown function (DUF4382) - - - 0.000000003784 67.0
SHD2_k127_2239389_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 4.213e-258 815.0
SHD2_k127_2239389_1 THUMP K07444 - - 0.0003006 46.0
SHD2_k127_2240298_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 313.0
SHD2_k127_2240298_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000045 204.0
SHD2_k127_2240298_2 Domain of unknown function (DUF374) K09778 - - 0.00000000000001651 79.0
SHD2_k127_2242737_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 348.0
SHD2_k127_2242737_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179,K08941 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 333.0
SHD2_k127_2242737_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000001709 210.0
SHD2_k127_2243951_0 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 573.0
SHD2_k127_2243951_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 455.0
SHD2_k127_2251686_0 nucleotide catabolic process K05996 - 3.4.17.18 0.000000000000000002017 98.0
SHD2_k127_2251686_1 - - - - 0.0000000002409 63.0
SHD2_k127_2251926_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000001085 158.0
SHD2_k127_2251926_1 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000261 136.0
SHD2_k127_2251926_2 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000002313 129.0
SHD2_k127_2251926_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000006263 54.0
SHD2_k127_2251926_4 Putative zinc-finger - - - 0.0002068 51.0
SHD2_k127_2252366_0 Transglycosylase - - - 0.000000000000000000000000000000000000001564 151.0
SHD2_k127_2252366_1 serine threonine protein kinase - - - 0.0000000000000003503 92.0
SHD2_k127_2274641_0 Protein of unknown function (DUF2723) K14340 - - 0.000000000000004637 88.0
SHD2_k127_2275858_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 1.452e-266 839.0
SHD2_k127_2275858_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 332.0
SHD2_k127_2275858_2 MgtC family K07507 - - 0.00000000000000000000005409 101.0
SHD2_k127_2275858_3 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.00000000000000000001355 96.0
SHD2_k127_2276494_0 NADH flavin oxidoreductase K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 487.0
SHD2_k127_2280953_0 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001151 272.0
SHD2_k127_2284688_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 420.0
SHD2_k127_2284688_1 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000007056 120.0
SHD2_k127_2284688_2 Belongs to the UPF0434 family K09791 - - 0.000000000000001586 79.0
SHD2_k127_2284688_3 Peptidase family C25 - - - 0.0000005764 61.0
SHD2_k127_2288233_0 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000001095 87.0
SHD2_k127_2288233_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000002752 66.0
SHD2_k127_2294425_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 460.0
SHD2_k127_2294425_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000001599 197.0
SHD2_k127_2294425_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000005285 85.0
SHD2_k127_229949_0 transcription factor binding K02584,K11914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 326.0
SHD2_k127_229949_1 Diguanylate cyclase - - - 0.000000000000000000000000001638 128.0
SHD2_k127_229949_2 Tetratricopeptide repeat - - - 0.0001038 54.0
SHD2_k127_2310771_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000001484 276.0
SHD2_k127_2310771_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000005796 202.0
SHD2_k127_2310771_2 PFAM membrane protein of K08972 - - 0.0000000000009464 71.0
SHD2_k127_2310771_3 Winged helix-turn-helix domain (DUF2582) - - - 0.0000005219 53.0
SHD2_k127_2315920_0 PFAM Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 481.0
SHD2_k127_2315920_1 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000001321 181.0
SHD2_k127_2317379_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.79e-239 756.0
SHD2_k127_2317379_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000007411 228.0
SHD2_k127_2317379_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001459 131.0
SHD2_k127_2317379_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0005045 47.0
SHD2_k127_2326110_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000005245 190.0
SHD2_k127_2326110_1 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000000000007572 173.0
SHD2_k127_2326110_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000009926 156.0
SHD2_k127_2326110_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000001585 151.0
SHD2_k127_2326110_4 PFAM SpoVT AbrB domain protein K07172 - - 0.0000000000000000002228 90.0
SHD2_k127_2326110_5 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21562 - - 0.0000000000001698 79.0
SHD2_k127_2344185_0 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000007961 159.0
SHD2_k127_2344185_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000004572 160.0
SHD2_k127_2351692_0 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000136 219.0
SHD2_k127_2351692_1 BMC - - - 0.0000000000000000000000000006517 120.0
SHD2_k127_2351692_2 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000009727 93.0
SHD2_k127_2351692_3 Belongs to the glycosyl hydrolase 13 family - - - 0.000001053 54.0
SHD2_k127_2370758_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007601 258.0
SHD2_k127_2370758_1 MATE efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000007885 213.0
SHD2_k127_2375557_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000004623 109.0
SHD2_k127_2375557_1 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000813 56.0
SHD2_k127_2375843_0 response to heat K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 423.0
SHD2_k127_2375843_1 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 413.0
SHD2_k127_2375843_2 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.000000002602 65.0
SHD2_k127_2375843_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000003879 54.0
SHD2_k127_2396702_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1093.0
SHD2_k127_2396702_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 349.0
SHD2_k127_2396702_2 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000001335 252.0
SHD2_k127_2396702_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000001705 240.0
SHD2_k127_2396702_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000002357 141.0
SHD2_k127_2396702_5 STAS domain K04749 - - 0.0000000000000000000000002958 108.0
SHD2_k127_2396702_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 0.00000000000000000000008853 108.0
SHD2_k127_2396702_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000002875 100.0
SHD2_k127_2396702_8 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000316 92.0
SHD2_k127_2401090_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 456.0
SHD2_k127_2401090_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 358.0
SHD2_k127_2401090_10 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000007606 131.0
SHD2_k127_2401090_11 SpoVG K06412 - - 0.000000000000000000000009985 104.0
SHD2_k127_2401090_12 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000003294 98.0
SHD2_k127_2401090_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000007599 94.0
SHD2_k127_2401090_14 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00008272 52.0
SHD2_k127_2401090_15 - - - - 0.0002472 53.0
SHD2_k127_2401090_2 tRNA synthetases class II (A) K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 292.0
SHD2_k127_2401090_3 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002197 265.0
SHD2_k127_2401090_4 Male sterility protein K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000002072 250.0
SHD2_k127_2401090_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000001646 205.0
SHD2_k127_2401090_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000001076 195.0
SHD2_k127_2401090_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000009821 183.0
SHD2_k127_2401090_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000002956 161.0
SHD2_k127_2401090_9 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000005567 136.0
SHD2_k127_2407901_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 301.0
SHD2_k127_2407901_1 amine dehydrogenase activity - - - 0.0000000002719 72.0
SHD2_k127_2412697_0 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation K08282,K13419 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 362.0
SHD2_k127_2412697_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001247 270.0
SHD2_k127_2416261_0 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007028 282.0
SHD2_k127_2416261_1 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000469 265.0
SHD2_k127_2416261_2 Peptidase family M1 domain - - - 0.0000008413 57.0
SHD2_k127_2438549_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 412.0
SHD2_k127_2438549_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 362.0
SHD2_k127_2438549_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000000003871 257.0
SHD2_k127_2438549_3 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000007919 215.0
SHD2_k127_2438549_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000001387 132.0
SHD2_k127_2438549_5 Universal bacterial protein YeaZ K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00006391 50.0
SHD2_k127_2440226_0 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003036 255.0
SHD2_k127_2440226_1 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000004288 180.0
SHD2_k127_2440226_2 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000001219 96.0
SHD2_k127_2440226_3 Pectic acid lyase - - - 0.00001145 58.0
SHD2_k127_2441075_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000002819 210.0
SHD2_k127_2441075_1 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000133 209.0
SHD2_k127_2441482_0 Transglycosylase K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 310.0
SHD2_k127_2441482_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000000000001456 168.0
SHD2_k127_2448260_0 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000007969 165.0
SHD2_k127_2448260_1 Transposase - - - 0.0000000000002617 80.0
SHD2_k127_2449129_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 304.0
SHD2_k127_2449129_1 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000000000005296 105.0
SHD2_k127_2453999_0 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 301.0
SHD2_k127_2453999_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 298.0
SHD2_k127_2453999_2 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009687 284.0
SHD2_k127_2453999_3 Acid phosphatase homologues - - - 0.000000000000000000000000000000000002423 149.0
SHD2_k127_2453999_4 hyperosmotic response - - - 0.0000000000000000000000000002516 123.0
SHD2_k127_2453999_5 Domain of unknown function (DUF362) - - - 0.000000000000000000000001309 103.0
SHD2_k127_2458403_0 C terminal of Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000001746 145.0
SHD2_k127_2458403_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000002227 70.0
SHD2_k127_2458403_2 selT selW selH selenoprotein K07401 - - 0.0000000001802 63.0
SHD2_k127_2458403_3 Tetratricopeptide repeat - - - 0.0002146 51.0
SHD2_k127_2462554_0 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001032 274.0
SHD2_k127_2462554_1 lipolytic protein G-D-S-L family - - - 0.000000000000004533 79.0
SHD2_k127_2482132_0 Protein of unknown function (DUF2723) K16928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 455.0
SHD2_k127_2482132_1 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 351.0
SHD2_k127_2482132_2 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000448 257.0
SHD2_k127_2482132_3 Glycosyltransferase like family 2 - - - 0.000000000000008507 76.0
SHD2_k127_2482820_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 344.0
SHD2_k127_2482820_1 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000004883 115.0
SHD2_k127_2482820_2 Sulfotransferase family - - - 0.0000005611 63.0
SHD2_k127_2482820_3 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000001574 60.0
SHD2_k127_2497988_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 522.0
SHD2_k127_2497988_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000001264 256.0
SHD2_k127_2497988_2 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000004114 107.0
SHD2_k127_2497988_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000007509 104.0
SHD2_k127_2499312_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 340.0
SHD2_k127_2499312_1 Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 349.0
SHD2_k127_2499312_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000002494 177.0
SHD2_k127_2499312_3 Regulatory protein, FmdB family - - - 0.000000000000000000000004219 105.0
SHD2_k127_2501210_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 418.0
SHD2_k127_2501210_1 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000001244 143.0
SHD2_k127_2501210_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000006629 124.0
SHD2_k127_2501210_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000004394 123.0
SHD2_k127_2501210_4 Transcriptional regulator - - - 0.000000000000000000000000005609 117.0
SHD2_k127_2501210_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000006931 63.0
SHD2_k127_2507605_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007934 282.0
SHD2_k127_2507605_1 YCII-related domain - - - 0.0000000000000000000000000000000000001187 145.0
SHD2_k127_2507605_2 - - - - 0.000000000000000000000000004621 124.0
SHD2_k127_2518206_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.365e-197 636.0
SHD2_k127_2518206_1 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000001944 209.0
SHD2_k127_2518206_2 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.000000000000000000000000000000000000000000002039 178.0
SHD2_k127_2518206_3 arylsulfatase activity K01133 - 3.1.6.6 0.0000000000000000000000000000000000002605 162.0
SHD2_k127_2518206_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000001096 120.0
SHD2_k127_2518206_5 - - - - 0.000000000000000008983 96.0
SHD2_k127_2518206_6 - - - - 0.00008576 51.0
SHD2_k127_252667_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006173 263.0
SHD2_k127_252667_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000001574 226.0
SHD2_k127_252667_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000002157 214.0
SHD2_k127_252667_3 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000006553 172.0
SHD2_k127_252667_4 polysaccharide biosynthetic process - - - 0.000000000000000000000000001359 129.0
SHD2_k127_252667_5 -O-antigen K18814 - - 0.0000000000000000000000005094 120.0
SHD2_k127_252728_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 7.057e-274 851.0
SHD2_k127_2529633_0 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000002242 190.0
SHD2_k127_2529633_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000006907 135.0
SHD2_k127_253446_0 (ABC) transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 415.0
SHD2_k127_253446_1 Peptidase family M1 domain K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 401.0
SHD2_k127_253446_2 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 364.0
SHD2_k127_253446_3 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000001151 246.0
SHD2_k127_253446_4 photosystem I assembly BtpA K06971 - - 0.00000000000000000000000000000000000000000000000000000000000000000002272 251.0
SHD2_k127_2536888_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 283.0
SHD2_k127_2536888_1 glutamate decarboxylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003431 261.0
SHD2_k127_2536888_4 6-phosphogluconolactonase activity - - - 0.000000000000003202 77.0
SHD2_k127_2542989_0 DinB family - - - 0.000000000000000000000000000000000001612 144.0
SHD2_k127_2542989_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000005252 109.0
SHD2_k127_2542989_2 Nitrate reductase delta subunit - - - 0.0000001249 61.0
SHD2_k127_2544558_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000003974 180.0
SHD2_k127_2544558_1 extracellular matrix structural constituent - - - 0.000000001305 66.0
SHD2_k127_2552494_0 - - - - 3.859e-238 760.0
SHD2_k127_2563030_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 490.0
SHD2_k127_25690_0 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 369.0
SHD2_k127_25690_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000003953 254.0
SHD2_k127_25690_2 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ K11910 - - 0.00000000000000000000000000000000000000000000000000000000000007077 232.0
SHD2_k127_25690_3 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000002453 211.0
SHD2_k127_25690_4 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.000000000000000000000000000000000000000000000000000000000676 205.0
SHD2_k127_25690_5 cAMP biosynthetic process - - - 0.00000000000000000000003588 113.0
SHD2_k127_25690_6 Curli production assembly/transport component CsgG - - - 0.0000000000005332 81.0
SHD2_k127_25690_7 Galactose oxidase, central domain - - - 0.000000001796 71.0
SHD2_k127_25690_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000192 55.0
SHD2_k127_2578568_0 pfam psp1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005024 251.0
SHD2_k127_2578568_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000004589 231.0
SHD2_k127_2578568_2 'dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000000000000000000001415 146.0
SHD2_k127_2578568_3 Carboxypeptidase regulatory-like domain - - - 0.0000000004127 70.0
SHD2_k127_2580577_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 536.0
SHD2_k127_2580577_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001203 214.0
SHD2_k127_2580577_2 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000003134 157.0
SHD2_k127_2580577_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000002709 152.0
SHD2_k127_2580577_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000006663 134.0
SHD2_k127_2580577_5 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001956 77.0
SHD2_k127_25847_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001012 291.0
SHD2_k127_25847_1 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000001283 72.0
SHD2_k127_2589281_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 463.0
SHD2_k127_2589281_1 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000004371 150.0
SHD2_k127_2589281_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000005367 107.0
SHD2_k127_2589281_3 PFAM Helix-turn-helix K07729 - - 0.000000000000000000143 89.0
SHD2_k127_2589281_4 - - - - 0.000005126 52.0
SHD2_k127_2591377_0 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 340.0
SHD2_k127_2591377_1 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 292.0
SHD2_k127_2591377_2 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000002501 134.0
SHD2_k127_2591377_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000004692 85.0
SHD2_k127_2592846_0 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 294.0
SHD2_k127_2592846_1 cyclopropane-fatty-acyl-phospholipid synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006902 267.0
SHD2_k127_2592846_2 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001188 273.0
SHD2_k127_2594703_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 295.0
SHD2_k127_2594703_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005259 285.0
SHD2_k127_2594703_2 Sporulation and spore germination - - - 0.000000000001483 71.0
SHD2_k127_260707_0 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009031 379.0
SHD2_k127_260707_1 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 352.0
SHD2_k127_2608172_0 Pro-kumamolisin, activation domain - - - 0.000000007477 68.0
SHD2_k127_2608286_0 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 460.0
SHD2_k127_2608286_1 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000954 190.0
SHD2_k127_2622847_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000001284 154.0
SHD2_k127_2622847_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000001255 72.0
SHD2_k127_2626051_0 response regulator, receiver K03413 - - 0.00000000000000000000000000000000000000000417 168.0
SHD2_k127_2626051_1 Chemotaxis phosphatase CheX K03409 - - 0.0000002997 55.0
SHD2_k127_2626051_2 NAD(P)H-binding - - - 0.000001851 55.0
SHD2_k127_2626525_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 305.0
SHD2_k127_2626525_1 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001958 269.0
SHD2_k127_2626525_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000002768 199.0
SHD2_k127_2626525_3 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000234 151.0
SHD2_k127_2626525_4 Glutamine amidotransferase domain - - - 0.0000009395 59.0
SHD2_k127_263654_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000003678 136.0
SHD2_k127_263654_1 EamA-like transporter family - - - 0.0000000000000000000000000001572 123.0
SHD2_k127_263654_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000002447 64.0
SHD2_k127_26379_0 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 480.0
SHD2_k127_26379_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 379.0
SHD2_k127_26379_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 359.0
SHD2_k127_26379_3 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 357.0
SHD2_k127_26379_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001074 276.0
SHD2_k127_26379_5 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 267.0
SHD2_k127_26379_6 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007716 252.0
SHD2_k127_26379_7 cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000004554 176.0
SHD2_k127_26379_8 Chloride channel K03281 - - 0.00000000009055 70.0
SHD2_k127_2672038_0 Type VI secretion, TssG K11895 - - 0.0000000000000000000000000000000000000000000000003482 192.0
SHD2_k127_2672038_1 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0000000000000000000000000000000000000000000001231 174.0
SHD2_k127_2673545_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000001681 151.0
SHD2_k127_2674587_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 604.0
SHD2_k127_2674587_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 347.0
SHD2_k127_2674587_2 Surface antigen - - - 0.00000000000000000000000000000000000002127 163.0
SHD2_k127_2674587_3 FtsZ-dependent cytokinesis - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000008976 90.0
SHD2_k127_2703580_0 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000001256 243.0
SHD2_k127_2703580_1 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000003449 231.0
SHD2_k127_2703580_2 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000000000000000732 101.0
SHD2_k127_2703580_3 IrrE N-terminal-like domain - - - 0.00001823 56.0
SHD2_k127_2708884_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 402.0
SHD2_k127_2708884_1 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000003338 168.0
SHD2_k127_2708884_2 cheY-homologous receiver domain - - - 0.000000000000000000000002265 110.0
SHD2_k127_272160_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000003886 125.0
SHD2_k127_272160_1 Heparinase II/III N-terminus - - - 0.000000000000000000004878 108.0
SHD2_k127_272160_2 Heparinase II/III N-terminus - - - 0.00000009747 57.0
SHD2_k127_2723717_0 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 405.0
SHD2_k127_2723717_1 Histidine kinase - - - 0.00000536 54.0
SHD2_k127_2728004_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1632.0
SHD2_k127_2728004_1 Belongs to the ompA family - - - 0.0000000000006439 77.0
SHD2_k127_2740686_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000003454 243.0
SHD2_k127_2740686_1 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000001471 234.0
SHD2_k127_2747535_0 protein secretion K08651 - 3.4.21.66 0.00000000000000009694 92.0
SHD2_k127_2747535_1 amino acid activation for nonribosomal peptide biosynthetic process K01176,K01448,K17713,K20952 GO:0003674,GO:0005198,GO:0005199,GO:0005575,GO:0005623,GO:0008150,GO:0009273,GO:0009987,GO:0030115,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 3.2.1.1,3.5.1.28 0.000000000004719 77.0
SHD2_k127_2747535_2 Histidine kinase-like ATPase domain - - - 0.000004342 55.0
SHD2_k127_2747535_3 Epidermal growth factor-like domain. - - - 0.00003174 55.0
SHD2_k127_274928_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000001816 211.0
SHD2_k127_274928_1 - - - - 0.00000000000000000000002582 112.0
SHD2_k127_2753962_0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 1.236e-257 807.0
SHD2_k127_2753962_1 Acid phosphatase homologues - - - 0.00000000000000000000006836 109.0
SHD2_k127_2753962_2 PQQ-like domain K05889 - 1.1.2.6 0.000000000000001224 88.0
SHD2_k127_2753962_3 COG0553 Superfamily II DNA RNA - - - 0.00002359 55.0
SHD2_k127_276153_0 component I K01665 - 2.6.1.85 0.000000000000000000000000000003549 122.0
SHD2_k127_276153_1 B12 binding domain - - - 0.00000000000000000000000005045 120.0
SHD2_k127_276153_2 Redoxin - - - 0.00000000000000000000006257 102.0
SHD2_k127_276153_3 Tetratricopeptide repeat - - - 0.0000003392 63.0
SHD2_k127_276153_4 Redoxin - - - 0.000003578 49.0
SHD2_k127_276409_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 457.0
SHD2_k127_276409_1 alpha beta K06889 - - 0.000000000000000000000000224 111.0
SHD2_k127_276409_2 Histidine kinase K11383 - 2.7.13.3 0.0000000000002257 82.0
SHD2_k127_276409_3 OprF membrane domain K03286 - - 0.0000000008418 67.0
SHD2_k127_2764865_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 377.0
SHD2_k127_2764865_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000183 114.0
SHD2_k127_2764865_2 protein secretion K09800 - - 0.0000000000000001465 93.0
SHD2_k127_277635_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 580.0
SHD2_k127_277635_1 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 299.0
SHD2_k127_277635_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000001894 154.0
SHD2_k127_2783176_0 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000004952 260.0
SHD2_k127_2783176_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000004498 179.0
SHD2_k127_2783176_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000001885 141.0
SHD2_k127_2783176_3 Helix-turn-helix transcriptional regulator PuuR, cupin domain-containing - - - 0.0000000000000000000386 98.0
SHD2_k127_2842203_0 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 354.0
SHD2_k127_2842203_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 303.0
SHD2_k127_2842203_2 Binding-protein-dependent transport system inner membrane component K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003848 274.0
SHD2_k127_2848747_0 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 321.0
SHD2_k127_2848747_1 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000402 203.0
SHD2_k127_2848747_2 Belongs to the peptidase S8 family K08651,K14743 - 3.4.21.66 0.000000000000000000000000000000000000000000000000003344 200.0
SHD2_k127_2848747_3 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000723 181.0
SHD2_k127_2848747_4 purine nucleobase transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000001767 143.0
SHD2_k127_2848747_5 belongs to the sigma-70 factor family, ECF subfamily - - - 0.000000000000000000000000005814 118.0
SHD2_k127_2864790_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000005587 263.0
SHD2_k127_2864790_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000007459 153.0
SHD2_k127_2879793_0 Glycolate oxidase subunit K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 348.0
SHD2_k127_2879793_1 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 351.0
SHD2_k127_2879793_2 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000003707 196.0
SHD2_k127_2915202_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000363 197.0
SHD2_k127_2915202_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000001876 168.0
SHD2_k127_2915202_2 Nucleotidyl transferase of unknown function (DUF2204) - - - 0.00000002654 56.0
SHD2_k127_2948873_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 319.0
SHD2_k127_29620_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 377.0
SHD2_k127_296477_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 574.0
SHD2_k127_296477_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000003596 192.0
SHD2_k127_296477_2 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000004161 121.0
SHD2_k127_296477_3 Lipopolysaccharide-assembly - - - 0.00000000009859 69.0
SHD2_k127_299261_0 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000816 97.0
SHD2_k127_3000806_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000003897 134.0
SHD2_k127_3000806_1 Belongs to the peptidase S8 family K06113,K12685 - 3.2.1.99 0.00000000001144 75.0
SHD2_k127_3023716_0 AAA ATPase domain - - - 0.00000000000000000000000000009346 132.0
SHD2_k127_3132248_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006882 264.0
SHD2_k127_315377_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 586.0
SHD2_k127_315377_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 387.0
SHD2_k127_315377_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 318.0
SHD2_k127_315377_3 malonyl CoA-acyl carrier protein transacylase K00645,K15327,K15329,K15355,K15469 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000005645 284.0
SHD2_k127_315377_4 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000002088 274.0
SHD2_k127_315377_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000002707 205.0
SHD2_k127_315377_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000002709 152.0
SHD2_k127_315377_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000002108 113.0
SHD2_k127_315377_8 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000008071 110.0
SHD2_k127_315377_9 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000004558 89.0
SHD2_k127_3172581_0 ATPase with chaperone activity K07391 - - 0.000000000000008505 77.0
SHD2_k127_3172581_1 tetratricopeptide repeat - - - 0.00000000000414 76.0
SHD2_k127_3172581_2 Tetratricopeptide repeat - - - 0.000000004078 67.0
SHD2_k127_3179055_0 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000009705 232.0
SHD2_k127_3185367_0 PFAM ABC transporter K02056 - 3.6.3.17 9.32e-202 641.0
SHD2_k127_3185367_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 410.0
SHD2_k127_3185367_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 372.0
SHD2_k127_3186975_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001032 262.0
SHD2_k127_3186975_1 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000002137 229.0
SHD2_k127_3186975_2 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000002527 111.0
SHD2_k127_3187792_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 525.0
SHD2_k127_3187792_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 308.0
SHD2_k127_3187792_2 Transcriptional regulator PadR-like family - - - 0.00000000000000000004927 93.0
SHD2_k127_3200071_0 Carbohydrate phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 557.0
SHD2_k127_3200071_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 318.0
SHD2_k127_3203261_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 412.0
SHD2_k127_3207547_0 metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 305.0
SHD2_k127_3207547_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 295.0
SHD2_k127_3207547_2 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000003736 224.0
SHD2_k127_3208400_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 599.0
SHD2_k127_3208400_1 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 410.0
SHD2_k127_3208400_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000009477 132.0
SHD2_k127_3219891_0 Transport of potassium into the cell K03549 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 376.0
SHD2_k127_3221241_0 Subtilase family - - - 0.00000000000000000004928 105.0
SHD2_k127_3221241_1 M6 family metalloprotease domain protein - - - 0.000000000000327 83.0
SHD2_k127_3221289_0 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000000001538 174.0
SHD2_k127_3221289_1 Cytochrome oxidase assembly protein K02259,K03110 - - 0.00000000000000000000000000000000000005832 158.0
SHD2_k127_3223778_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 316.0
SHD2_k127_3223778_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 289.0
SHD2_k127_3223778_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000007356 121.0
SHD2_k127_3238468_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004627 282.0
SHD2_k127_3238468_1 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008081 265.0
SHD2_k127_3238468_2 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000000000000000005592 177.0
SHD2_k127_3238468_3 COG0515 Serine threonine protein kinase - - - 0.000000000000000000000000006843 126.0
SHD2_k127_3238468_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00001049 56.0
SHD2_k127_3243220_0 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 321.0
SHD2_k127_3243220_1 Peptidase M15 - - - 0.00000000000000000000000000000000000000000006458 176.0
SHD2_k127_3244441_0 plastoquinone (Complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 522.0
SHD2_k127_3244441_1 Hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000003379 182.0
SHD2_k127_3244441_2 NADH dehydrogenase - - - 0.00000000000000000000000000000000000002964 147.0
SHD2_k127_3245527_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 6.851e-256 803.0
SHD2_k127_3245527_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 460.0
SHD2_k127_3245527_2 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 403.0
SHD2_k127_3249899_0 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 402.0
SHD2_k127_3249899_1 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 327.0
SHD2_k127_3249899_2 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.00000000000000000000004209 100.0
SHD2_k127_3256469_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000003291 119.0
SHD2_k127_3256872_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 384.0
SHD2_k127_3256872_1 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000003016 245.0
SHD2_k127_3256872_2 mRNA catabolic process K06950 - - 0.0000000000000000000000000000000000000000000000000002441 189.0
SHD2_k127_3256872_3 NUDIX domain - - - 0.000000000000000000000000000000000000002141 154.0
SHD2_k127_3256872_4 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000004887 81.0
SHD2_k127_3256872_5 DinB family - - - 0.00002656 46.0
SHD2_k127_3268466_1 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000008284 141.0
SHD2_k127_3268466_2 - - - - 0.000000000000000000002928 98.0
SHD2_k127_3268466_3 - - - - 0.000000000000009922 85.0
SHD2_k127_3271754_0 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000003368 146.0
SHD2_k127_3271754_1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000009418 105.0
SHD2_k127_3271754_2 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000001017 105.0
SHD2_k127_3272855_0 siderophore transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 551.0
SHD2_k127_3272855_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 324.0
SHD2_k127_3272855_2 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002266 295.0
SHD2_k127_3272855_3 HEPN domain - - - 0.000000000000000000000000000000000003298 143.0
SHD2_k127_3274009_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000007082 152.0
SHD2_k127_3274009_1 PPIC-type PPIASE domain K03769,K07533 - 5.2.1.8 0.0000000000000000000000000000000000009014 158.0
SHD2_k127_3274009_3 Bacteriochlorophyll chlorophyll K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000000000002602 120.0
SHD2_k127_3274009_4 agmatine deiminase activity K08589,K10536,K20276 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37,3.5.3.12 0.0000000004963 67.0
SHD2_k127_3279109_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 479.0
SHD2_k127_3279109_1 - - - - 0.00001975 55.0
SHD2_k127_3279845_0 PglZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 560.0
SHD2_k127_3279845_1 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.00000000000000000002055 106.0
SHD2_k127_3279845_2 COG1214 Inactive homolog of metal-dependent proteases K01409,K14742 - 2.3.1.234 0.0000000000000000001538 100.0
SHD2_k127_3281034_0 Methyl-accepting chemotaxis sensory transducer with Pas Pac sensor K02660 - - 0.00000000000000000000000000000000000000000000000000000002239 212.0
SHD2_k127_3281034_1 Kelch repeat-containing protein - - - 0.000000006978 66.0
SHD2_k127_3290039_0 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 599.0
SHD2_k127_3290039_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 332.0
SHD2_k127_3290039_2 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000388 137.0
SHD2_k127_3290039_3 Zinc metalloprotease (Elastase) - - - 0.00001496 56.0
SHD2_k127_3291050_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.63e-215 680.0
SHD2_k127_3291050_1 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 309.0
SHD2_k127_3291050_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 289.0
SHD2_k127_3291050_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000001613 207.0
SHD2_k127_3291050_4 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000001652 133.0
SHD2_k127_3291050_5 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000001004 126.0
SHD2_k127_3291050_6 - - - - 0.00000000000006027 73.0
SHD2_k127_3294447_0 Tetratricopeptide repeat - - - 0.00001124 55.0
SHD2_k127_3314201_0 metallopeptidase activity K01637 - 4.1.3.1 0.000000000000000000000000000000000000199 158.0
SHD2_k127_3315383_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000003695 190.0
SHD2_k127_3315383_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000004487 145.0
SHD2_k127_3317270_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001191 282.0
SHD2_k127_3317270_1 Cytochrome c K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000006148 252.0
SHD2_k127_3317270_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000009255 235.0
SHD2_k127_3317270_3 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000000000004264 200.0
SHD2_k127_3317270_4 PrcB C-terminal - - - 0.000009908 55.0
SHD2_k127_3323039_0 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 615.0
SHD2_k127_3323039_1 N-terminal domain of (some) glycogen debranching enzymes - - - 0.00000000000000000000000000000000000000001156 156.0
SHD2_k127_33234_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 521.0
SHD2_k127_3331442_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 474.0
SHD2_k127_3331442_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 321.0
SHD2_k127_3331442_2 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 0.00000000000000000000002319 112.0
SHD2_k127_3331940_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 2.236e-200 642.0
SHD2_k127_3331940_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000002626 122.0
SHD2_k127_3344380_0 elongation factor Tu domain 2 protein K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 532.0
SHD2_k127_3344380_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000007227 238.0
SHD2_k127_3344380_2 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000004069 149.0
SHD2_k127_3346099_0 drug transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000006697 199.0
SHD2_k127_3346099_1 Chloride channel K03281 - - 0.000000000000000000000000000001944 133.0
SHD2_k127_3346240_0 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000485 61.0
SHD2_k127_3351862_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 536.0
SHD2_k127_3351862_1 ABC 3 transport family K09816,K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 354.0
SHD2_k127_3351862_2 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001383 290.0
SHD2_k127_3351862_3 Belongs to the Fur family K03711 - - 0.00000000000000000000001191 106.0
SHD2_k127_3351862_4 - - - - 0.00000000000000003334 89.0
SHD2_k127_3351862_5 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01176 - 3.2.1.1 0.00001502 59.0
SHD2_k127_3358451_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.775e-239 780.0
SHD2_k127_3358451_1 Glycosyl transferases group 1 K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 376.0
SHD2_k127_3358451_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 364.0
SHD2_k127_3358451_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 319.0
SHD2_k127_3358451_4 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000007348 208.0
SHD2_k127_3358451_5 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000007922 158.0
SHD2_k127_3358451_6 Belongs to the BshC family K22136 - - 0.0000000000000000000000000000000000000004378 170.0
SHD2_k127_3358451_7 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000005729 146.0
SHD2_k127_3368368_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 604.0
SHD2_k127_3368368_1 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 549.0
SHD2_k127_3368368_2 coagulation factor 5 8 type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 423.0
SHD2_k127_3368368_3 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 319.0
SHD2_k127_3368368_4 SnoaL-like domain - - - 0.0000000000000000004125 94.0
SHD2_k127_3373388_0 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 403.0
SHD2_k127_3373388_1 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000001226 70.0
SHD2_k127_3382878_0 peptidyl-tyrosine sulfation K13992 - - 0.0000000000000000000000000000000000000000000003738 180.0
SHD2_k127_3382878_1 Signal transduction protein - - - 0.0000000000000000000000000000000443 139.0
SHD2_k127_3382878_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000005779 75.0
SHD2_k127_3383458_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000006305 239.0
SHD2_k127_3383458_1 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000001162 90.0
SHD2_k127_3383458_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000001832 56.0
SHD2_k127_3383458_3 Alpha/beta hydrolase family K06889 - - 0.0000002234 52.0
SHD2_k127_341694_0 cellulose binding - - - 1.019e-255 801.0
SHD2_k127_3417377_0 ferredoxin-NADP+ reductase activity K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 372.0
SHD2_k127_3417377_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.0000000000000000000000000000000000000000000002397 179.0
SHD2_k127_3417377_2 methyltransferase - - - 0.0000000000000000000000000000000000000000002358 169.0
SHD2_k127_3417377_3 Tellurite resistance protein TerB - - - 0.00000000000003024 85.0
SHD2_k127_3417404_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 342.0
SHD2_k127_3417404_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 316.0
SHD2_k127_341956_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 475.0
SHD2_k127_3420113_0 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000005817 259.0
SHD2_k127_3420113_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000006462 148.0
SHD2_k127_3434646_0 - - - - 0.0000000000003288 83.0
SHD2_k127_34400_0 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000001173 174.0
SHD2_k127_34400_1 - - - - 0.000000000000000000000000001095 114.0
SHD2_k127_34400_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000001247 114.0
SHD2_k127_3444533_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 379.0
SHD2_k127_3444533_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000001148 228.0
SHD2_k127_3444533_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.0000000000000000000000000000000000000000006325 164.0
SHD2_k127_3444533_3 outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000003495 76.0
SHD2_k127_3444533_4 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.00001512 48.0
SHD2_k127_3463157_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002884 270.0
SHD2_k127_3463157_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000001417 212.0
SHD2_k127_3463157_2 Domain of unknown function (DUF1844) - - - 0.0000004448 58.0
SHD2_k127_346361_0 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000004483 147.0
SHD2_k127_3477094_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 503.0
SHD2_k127_3478319_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 282.0
SHD2_k127_3478319_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000008781 242.0
SHD2_k127_3478319_2 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000001891 246.0
SHD2_k127_3478319_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.0000000000000000000000000000000000000000000000001357 187.0
SHD2_k127_3478319_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000705 168.0
SHD2_k127_3478319_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000001039 171.0
SHD2_k127_3478319_6 NAD binding K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000003916 158.0
SHD2_k127_3478319_7 Putative adhesin - - - 0.0000000000000000000000002214 118.0
SHD2_k127_3478319_8 AntiSigma factor K00567 - 2.1.1.63 0.000005017 57.0
SHD2_k127_3478768_0 domain protein K07260 - 3.4.17.14 0.0000000000000000000000000000000708 144.0
SHD2_k127_3478876_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 351.0
SHD2_k127_3478876_1 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000003517 196.0
SHD2_k127_3478876_2 - - - - 0.000000004842 61.0
SHD2_k127_3481925_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 418.0
SHD2_k127_3481925_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 346.0
SHD2_k127_3481925_2 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000007454 256.0
SHD2_k127_3481925_3 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000004374 160.0
SHD2_k127_3481925_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000001715 83.0
SHD2_k127_3481925_5 VanZ like family - - - 0.000001382 56.0
SHD2_k127_3481925_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0007365 43.0
SHD2_k127_3489760_0 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000001252 196.0
SHD2_k127_350049_0 DEAD DEAH box helicase K03724 - - 0.0 1063.0
SHD2_k127_350049_1 PAS PAC sensor hybrid histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 470.0
SHD2_k127_350049_2 Belongs to the serpin family K13963,K13966 GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0009892,GO:0009894,GO:0009987,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034774,GO:0036230,GO:0042119,GO:0042176,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0043299,GO:0043312,GO:0044092,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 265.0
SHD2_k127_350624_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000005328 117.0
SHD2_k127_350624_1 ethanolamine kinase activity K07251 - 2.7.1.89 0.000004699 58.0
SHD2_k127_3507581_0 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 499.0
SHD2_k127_3507581_1 PFAM BMC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 302.0
SHD2_k127_3507581_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000002832 143.0
SHD2_k127_3507581_3 BMC K04027 - - 0.000000000000000000000000000000000003432 144.0
SHD2_k127_3507581_4 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000001389 106.0
SHD2_k127_3507581_5 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0003797 46.0
SHD2_k127_3524495_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.519e-197 633.0
SHD2_k127_3524495_1 sporulation initiation inhibitor protein Soj K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 310.0
SHD2_k127_3524495_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000001856 111.0
SHD2_k127_3547683_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 1.576e-243 758.0
SHD2_k127_3547683_2 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000002525 55.0
SHD2_k127_3565661_0 Ribosomal large subunit pseudouridine synthase A K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 323.0
SHD2_k127_3594908_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 325.0
SHD2_k127_3594908_1 oxidoreductase activity - - - 0.00000000000000000000003824 100.0
SHD2_k127_3602351_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 567.0
SHD2_k127_3602351_1 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000000004659 195.0
SHD2_k127_3602351_2 extracellular matrix structural constituent - - - 0.00000004306 66.0
SHD2_k127_3609681_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000001342 128.0
SHD2_k127_3609681_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0001846 44.0
SHD2_k127_361267_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 585.0
SHD2_k127_361267_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000001588 212.0
SHD2_k127_3612674_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 558.0
SHD2_k127_3612674_1 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000007768 178.0
SHD2_k127_3612674_2 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000004228 125.0
SHD2_k127_361629_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000004495 205.0
SHD2_k127_361629_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000006666 203.0
SHD2_k127_3619793_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008921 481.0
SHD2_k127_3619793_1 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 460.0
SHD2_k127_3619793_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 451.0
SHD2_k127_3619793_3 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 342.0
SHD2_k127_3619793_4 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000001869 207.0
SHD2_k127_3619793_5 - - - - 0.00000000000000000000001384 116.0
SHD2_k127_3619793_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000008741 64.0
SHD2_k127_3635094_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000002898 138.0
SHD2_k127_3635094_1 - - - - 0.00000000000001307 88.0
SHD2_k127_3644924_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 333.0
SHD2_k127_3644924_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000009288 232.0
SHD2_k127_3644924_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000005607 206.0
SHD2_k127_3649625_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000001655 199.0
SHD2_k127_3649625_1 Glycosyl transferase 4-like domain - - - 0.000000000003269 80.0
SHD2_k127_3649625_2 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000005377 62.0
SHD2_k127_3671322_0 Ribosomal protein S1 K02945,K03527,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 1.384e-210 676.0
SHD2_k127_3671322_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 364.0
SHD2_k127_3671322_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000005166 211.0
SHD2_k127_3671322_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000005548 201.0
SHD2_k127_3671322_4 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000004008 63.0
SHD2_k127_3671322_5 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000003913 65.0
SHD2_k127_3688567_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 465.0
SHD2_k127_3707661_0 PFAM TrkA-C domain protein K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 302.0
SHD2_k127_3707661_1 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000003633 227.0
SHD2_k127_3707661_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07715 - - 0.000000000000000000000000000000000000000000000001713 186.0
SHD2_k127_3707661_3 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000001475 85.0
SHD2_k127_3712758_0 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 286.0
SHD2_k127_3712758_1 type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000001471 243.0
SHD2_k127_3712758_2 PFAM Pilus assembly protein PilO K02664 - - 0.0000000000000000003767 97.0
SHD2_k127_3712758_3 oligosaccharyl transferase activity - - - 0.00000000000000002721 95.0
SHD2_k127_3712758_4 PFAM Fimbrial assembly family protein K02663 - - 0.000000000002335 76.0
SHD2_k127_3717583_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 466.0
SHD2_k127_3717583_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 411.0
SHD2_k127_3717583_2 converts alpha-aldose to the beta-anomer - - - 0.00000003567 64.0
SHD2_k127_3726139_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 317.0
SHD2_k127_3726139_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006966 284.0
SHD2_k127_3726139_2 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000001614 250.0
SHD2_k127_3726139_3 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000005563 239.0
SHD2_k127_3726139_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000008427 151.0
SHD2_k127_3726139_5 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000501 121.0
SHD2_k127_3726139_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000002285 108.0
SHD2_k127_3726139_7 Nucleotidyl transferase K11528 - 2.7.7.23 0.0000000000000000000005189 104.0
SHD2_k127_3726139_8 Tetratricopeptide TPR_2 repeat protein - - - 0.00001458 59.0
SHD2_k127_3732921_0 Pyridoxal-phosphate dependent enzyme - - - 2.307e-210 668.0
SHD2_k127_3732921_1 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 307.0
SHD2_k127_3732921_2 Amidohydrolase family - - - 0.00001271 48.0
SHD2_k127_3742698_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 459.0
SHD2_k127_3742698_1 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 384.0
SHD2_k127_3742698_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000649 68.0
SHD2_k127_3747805_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 376.0
SHD2_k127_3747805_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 346.0
SHD2_k127_3764318_0 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 441.0
SHD2_k127_3764318_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001943 271.0
SHD2_k127_3769673_0 Abc transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000002525 215.0
SHD2_k127_3769673_1 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000005267 161.0
SHD2_k127_3787862_0 ApbE family K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 306.0
SHD2_k127_3787862_1 glycoside hydrolase family 81 - - - 0.00000000005031 74.0
SHD2_k127_3824956_0 Mo-molybdopterin cofactor biosynthetic process K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000002116 249.0
SHD2_k127_3824956_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000012 138.0
SHD2_k127_3824956_2 Conserved repeat domain - - - 0.000000000000000003052 91.0
SHD2_k127_3842588_0 Aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 477.0
SHD2_k127_3842588_1 - - - - 0.0000000000000003954 91.0
SHD2_k127_3842588_2 Acetyltransferase (GNAT) domain - - - 0.0002075 48.0
SHD2_k127_3865712_0 lysine biosynthetic process via aminoadipic acid - - - 5.865e-212 691.0
SHD2_k127_3865712_1 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007851 274.0
SHD2_k127_3865712_2 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000127 226.0
SHD2_k127_3872607_0 General secretory system II protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 499.0
SHD2_k127_3872607_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003218 271.0
SHD2_k127_3872607_2 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009651 276.0
SHD2_k127_3872607_3 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000001656 216.0
SHD2_k127_3872607_4 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000001093 224.0
SHD2_k127_3872607_6 Methyltransferase domain - - - 0.00000000236 69.0
SHD2_k127_3872607_7 Belongs to the UPF0434 family K09791 - - 0.000002686 59.0
SHD2_k127_3909070_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 404.0
SHD2_k127_3917626_0 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 424.0
SHD2_k127_3917626_1 xyloglucan:xyloglucosyl transferase activity K01216,K07004 - 3.2.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 302.0
SHD2_k127_3933848_0 ABC transporter, transmembrane K11085 - - 5.878e-214 675.0
SHD2_k127_3933848_1 Haem-binding domain - - - 0.00000000000000000000000000000000003316 140.0
SHD2_k127_3933848_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000007777 84.0
SHD2_k127_3937939_0 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000005507 221.0
SHD2_k127_3937939_1 Histidine kinase - - - 0.000000000000000000000000000000000001122 146.0
SHD2_k127_3959784_0 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 0.00000000000000000000000000000000005595 146.0
SHD2_k127_3959784_1 spermidine synthase - - - 0.0001138 53.0
SHD2_k127_3962280_0 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 351.0
SHD2_k127_3962280_1 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.00000000000000000000000000000002316 141.0
SHD2_k127_39627_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 347.0
SHD2_k127_39627_1 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000662 269.0
SHD2_k127_39627_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000002307 164.0
SHD2_k127_3974589_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007812 238.0
SHD2_k127_3988260_0 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 311.0
SHD2_k127_3988260_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001033 277.0
SHD2_k127_3988260_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002319 277.0
SHD2_k127_3988260_3 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002957 273.0
SHD2_k127_3988260_4 - - - - 0.00000000000000000004561 100.0
SHD2_k127_3988260_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000007453 89.0
SHD2_k127_3991982_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 490.0
SHD2_k127_3991982_1 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000009866 183.0
SHD2_k127_3991982_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000009054 71.0
SHD2_k127_3998292_0 Peptidase family M3 K01392 - 3.4.24.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 548.0
SHD2_k127_4013292_0 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 320.0
SHD2_k127_4018898_0 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000134 166.0
SHD2_k127_4018898_1 PFAM CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000000000000000006264 109.0
SHD2_k127_4018898_2 - - - - 0.000000000006057 78.0
SHD2_k127_4018898_3 Capsular exopolysaccharide family K16554 - - 0.00001815 49.0
SHD2_k127_4024163_0 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000008569 104.0
SHD2_k127_4081907_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 354.0
SHD2_k127_4081907_1 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000398 171.0
SHD2_k127_4081907_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000008332 119.0
SHD2_k127_408995_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000006995 107.0
SHD2_k127_408995_1 Histidine kinase - - - 0.000000122 64.0
SHD2_k127_408995_2 Binds directly to 16S ribosomal RNA K02968 - - 0.000008955 55.0
SHD2_k127_4102649_0 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 - - 0.0001801 54.0
SHD2_k127_412879_0 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 374.0
SHD2_k127_412879_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000001408 146.0
SHD2_k127_412879_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000006594 126.0
SHD2_k127_412879_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000001483 85.0
SHD2_k127_412879_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000005642 75.0
SHD2_k127_4190304_0 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01848 - 5.4.99.2 6.15e-207 657.0
SHD2_k127_4190304_1 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002381 273.0
SHD2_k127_421591_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000005155 259.0
SHD2_k127_421591_1 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000002446 224.0
SHD2_k127_4227360_0 NlpC/P60 family - - - 0.000000000000000000000000000000000001499 153.0
SHD2_k127_4227360_1 Peptidase M56 - - - 0.0000000000000000000000000000000006903 148.0
SHD2_k127_4227360_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000004153 63.0
SHD2_k127_4229403_0 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000001987 254.0
SHD2_k127_4229403_1 - - - - 0.000000000000000001448 96.0
SHD2_k127_4233584_0 WD40-like Beta Propeller Repeat - - - 4.516e-318 1004.0
SHD2_k127_4233584_1 Prolyl oligopeptidase K01322 - 3.4.21.26 2.56e-212 682.0
SHD2_k127_4233584_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 553.0
SHD2_k127_4233584_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000009461 178.0
SHD2_k127_4233584_4 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000002207 53.0
SHD2_k127_4238964_0 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000006461 159.0
SHD2_k127_4243983_0 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 357.0
SHD2_k127_4243983_1 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000002253 235.0
SHD2_k127_4243983_2 SPTR Glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000009667 209.0
SHD2_k127_4243983_3 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000593 171.0
SHD2_k127_4244550_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 373.0
SHD2_k127_4244550_1 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004141 244.0
SHD2_k127_4246250_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 456.0
SHD2_k127_4246250_1 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 388.0
SHD2_k127_4246250_3 Belongs to the LOG family K06966 - 3.2.2.10 0.00001934 48.0
SHD2_k127_4246760_0 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000003932 203.0
SHD2_k127_4246760_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000001566 168.0
SHD2_k127_4246760_2 Putative bacterial lipoprotein (DUF799) - - - 0.0000000000000000004333 94.0
SHD2_k127_4246760_3 zinc ion binding K11997 - - 0.00000000000000004218 93.0
SHD2_k127_4246760_4 Putative bacterial lipoprotein (DUF799) - - - 0.000000001372 71.0
SHD2_k127_4246760_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000001758 69.0
SHD2_k127_4250745_0 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003578 279.0
SHD2_k127_4250745_1 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000008589 132.0
SHD2_k127_4250745_2 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000002422 133.0
SHD2_k127_4253475_0 Belongs to the peptidase M16 family K07263 - - 1.002e-263 833.0
SHD2_k127_4255337_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.484e-303 944.0
SHD2_k127_4255337_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000001912 210.0
SHD2_k127_4255337_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001206 198.0
SHD2_k127_4255337_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000152 82.0
SHD2_k127_4255452_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.733e-227 715.0
SHD2_k127_4255452_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 352.0
SHD2_k127_4255452_2 PFAM peptidase M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 299.0
SHD2_k127_4255452_3 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003512 256.0
SHD2_k127_4255452_4 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009776 241.0
SHD2_k127_4255452_5 Protein of unknown function (DUF1326) - - - 0.0003731 52.0
SHD2_k127_4257775_0 4Fe-4S dicluster domain K00184 - - 2.852e-210 687.0
SHD2_k127_4257775_1 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 287.0
SHD2_k127_4257775_2 Thioesterase domain - - - 0.0000000007844 62.0
SHD2_k127_4257897_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000002814 229.0
SHD2_k127_4257897_1 drug transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000002008 168.0
SHD2_k127_4261195_0 Major Facilitator Superfamily K03446 - - 8.066e-215 680.0
SHD2_k127_4261195_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 449.0
SHD2_k127_4261195_2 PFAM transferase hexapeptide repeat containing protein K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 395.0
SHD2_k127_4261195_3 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000089 174.0
SHD2_k127_4261195_4 Biotin-lipoyl like K03543 - - 0.0000000000000001247 83.0
SHD2_k127_4261195_5 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000008934 74.0
SHD2_k127_4262992_0 TonB-dependent receptor - - - 4.924e-260 829.0
SHD2_k127_4262992_2 cellulose binding K00505 - 1.14.18.1 0.00000000000000000000000000000000000000000000000000001745 200.0
SHD2_k127_4265380_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 470.0
SHD2_k127_4265380_1 AcrB/AcrD/AcrF family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 304.0
SHD2_k127_4269845_0 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 317.0
SHD2_k127_4269845_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000001272 231.0
SHD2_k127_4269845_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000102 184.0
SHD2_k127_4269845_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000426 146.0
SHD2_k127_4274490_0 PrkA AAA domain K07180 - - 0.0 1042.0
SHD2_k127_4274490_1 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 515.0
SHD2_k127_4274490_2 Threonine alanine tRNA ligase second additional domain protein K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 321.0
SHD2_k127_4274490_3 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000002227 249.0
SHD2_k127_4274490_4 SpoVR like protein K06415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001077 259.0
SHD2_k127_4274490_5 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000005329 172.0
SHD2_k127_4274490_6 Hit family K02503 - - 0.00000000000000000000000000000000000000001265 156.0
SHD2_k127_4274490_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000006108 141.0
SHD2_k127_4274490_8 PFAM thioesterase superfamily K07107 - - 0.000000000000000000000000000004377 125.0
SHD2_k127_4276624_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 1.099e-212 663.0
SHD2_k127_4276624_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002344 240.0
SHD2_k127_4277720_0 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000001749 144.0
SHD2_k127_4277720_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000001643 118.0
SHD2_k127_4277720_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000002502 91.0
SHD2_k127_4282684_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001042 276.0
SHD2_k127_4282684_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000005113 158.0
SHD2_k127_4282684_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000004369 112.0
SHD2_k127_4282684_3 Preprotein translocase subunit K03210 - - 0.000000000000000001168 94.0
SHD2_k127_4287068_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000002439 203.0
SHD2_k127_4291475_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 477.0
SHD2_k127_4291475_1 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 451.0
SHD2_k127_4291475_2 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 303.0
SHD2_k127_4291475_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000001117 218.0
SHD2_k127_4291475_4 Domain of unknown function DUF302 - - - 0.00000000000000000002984 92.0
SHD2_k127_4291475_5 Natural resistance-associated macrophage protein K03322 - - 0.00001643 49.0
SHD2_k127_4293550_0 ArgE DapE Acy1 family protein K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 480.0
SHD2_k127_4293550_1 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000004011 205.0
SHD2_k127_4293550_2 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000002355 153.0
SHD2_k127_4293550_3 Polymer-forming cytoskeletal - - - 0.00000000000006886 79.0
SHD2_k127_4297688_0 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 516.0
SHD2_k127_4297688_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 338.0
SHD2_k127_4297688_2 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 299.0
SHD2_k127_4297688_3 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000003794 248.0
SHD2_k127_4304609_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 580.0
SHD2_k127_4304609_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000239 162.0
SHD2_k127_4304609_2 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.000000000000000000301 96.0
SHD2_k127_4309257_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000002374 61.0
SHD2_k127_4309257_1 ompA family - - - 0.00009831 53.0
SHD2_k127_4310419_0 efflux pump K03296 - - 5.884e-235 743.0
SHD2_k127_4310419_1 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 564.0
SHD2_k127_431271_0 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 362.0
SHD2_k127_431271_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000006204 203.0
SHD2_k127_431271_2 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000002526 155.0
SHD2_k127_431271_3 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.00000000000000000000000004205 111.0
SHD2_k127_431271_4 Iron-sulphur cluster biosynthesis K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:1901564 - 0.0000000000000000000000003048 109.0
SHD2_k127_431271_5 Flavin and coenzyme A sequestration protein dodecin K09165 - - 0.0000000000000000000451 104.0
SHD2_k127_4322191_0 surface antigen - - - 0.000000000000000000000000002537 126.0
SHD2_k127_4322191_1 GAF domain K21405 - - 0.00000418 49.0
SHD2_k127_4322191_2 - - - - 0.0002141 51.0
SHD2_k127_4324678_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 451.0
SHD2_k127_4326684_0 MreB/Mbl protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 458.0
SHD2_k127_4326684_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 407.0
SHD2_k127_4326684_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 320.0
SHD2_k127_4326684_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000002018 125.0
SHD2_k127_4326684_4 (Rhomboid) family K07059 - - 0.00000000000000000001176 105.0
SHD2_k127_4326684_5 shape-determining protein MreD K03571 - - 0.0000000003503 67.0
SHD2_k127_4333229_0 Peptidase S9, prolyl oligopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 446.0
SHD2_k127_4333833_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000006593 200.0
SHD2_k127_4333833_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000001678 177.0
SHD2_k127_4333833_2 COG0457 FOG TPR repeat - - - 0.00001987 58.0
SHD2_k127_4334385_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000476 271.0
SHD2_k127_4334385_1 - - - - 0.000000000000000000000000000000000000000000000001268 183.0
SHD2_k127_4334385_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000004515 108.0
SHD2_k127_4334385_4 - - - - 0.00000001089 68.0
SHD2_k127_4334385_5 type IV pilus modification protein PilV K02458,K02671 - - 0.0000001915 60.0
SHD2_k127_4334385_6 Prokaryotic N-terminal methylation motif K08084 - - 0.00001278 53.0
SHD2_k127_4334385_7 - - - - 0.0000539 55.0
SHD2_k127_4339173_0 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000001247 119.0
SHD2_k127_4339173_1 Parallel beta-helix repeats - - - 0.0000002941 65.0
SHD2_k127_4339173_2 metallopeptidase activity K07404 - 3.1.1.31 0.0000008835 63.0
SHD2_k127_4339173_3 Mo-co oxidoreductase dimerisation domain - - - 0.000006057 61.0
SHD2_k127_4340919_0 Propeptide_C25 - - - 0.000000000000000000000000000000000000001342 171.0
SHD2_k127_4349348_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.89e-207 665.0
SHD2_k127_4349348_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005231 244.0
SHD2_k127_4349348_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000009929 197.0
SHD2_k127_4349348_3 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000003846 111.0
SHD2_k127_4349348_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000007555 113.0
SHD2_k127_4350830_0 Belongs to the ClpA ClpB family K03695,K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 578.0
SHD2_k127_4350830_1 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 - 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 340.0
SHD2_k127_4350830_2 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004125 248.0
SHD2_k127_4350830_3 protein with conserved CXXC pairs K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - 0.000000000000000000000000000000006809 135.0
SHD2_k127_4351154_0 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 472.0
SHD2_k127_4351154_1 Protein of unknown function (DUF3341) - - - 0.0000001855 57.0
SHD2_k127_4354236_0 Propeptide_C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 358.0
SHD2_k127_4355868_0 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 322.0
SHD2_k127_4357027_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004009 261.0
SHD2_k127_4357027_1 - - - - 0.0000000000000000000002103 110.0
SHD2_k127_4357027_2 zinc ion binding K11997 - - 0.000000001324 69.0
SHD2_k127_4357027_3 - - - - 0.000001197 60.0
SHD2_k127_4359970_0 Polysulphide reductase, NrfD K00185 - - 1.793e-215 677.0
SHD2_k127_4359970_1 4 iron, 4 sulfur cluster binding K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 420.0
SHD2_k127_4359970_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 354.0
SHD2_k127_4359970_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000004002 229.0
SHD2_k127_4359970_4 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000002322 228.0
SHD2_k127_4359970_5 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000002694 138.0
SHD2_k127_4359970_6 - - - - 0.00000009861 61.0
SHD2_k127_4362981_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 437.0
SHD2_k127_4362981_1 PFAM dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000005519 178.0
SHD2_k127_4362981_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.000000000000000000000006282 102.0
SHD2_k127_4370624_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001228 278.0
SHD2_k127_4370624_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000002073 213.0
SHD2_k127_4370624_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000003593 222.0
SHD2_k127_4371814_0 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000001001 226.0
SHD2_k127_4371814_1 Polysaccharide biosynthesis protein - - - 0.00001921 53.0
SHD2_k127_4371814_2 - - - - 0.00008364 53.0
SHD2_k127_4374579_0 Glutamine synthetase, catalytic region K01915 - 6.3.1.2 9.585e-242 768.0
SHD2_k127_4374579_1 Transglycosylase - - - 6.859e-218 699.0
SHD2_k127_4374579_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000002008 206.0
SHD2_k127_4374579_3 purine nucleotide biosynthetic process K02103,K02529 - - 0.000000001123 61.0
SHD2_k127_4379841_0 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005932 264.0
SHD2_k127_4379841_1 cellulase activity K06882 - - 0.000000000000000000001733 104.0
SHD2_k127_4380112_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 432.0
SHD2_k127_4380112_1 - - - - 0.0000000000000000000000000000000000000000000000006138 179.0
SHD2_k127_4385605_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000002236 213.0
SHD2_k127_4385605_1 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.000000000000000000000000000000000000000005623 173.0
SHD2_k127_4385605_2 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000001079 124.0
SHD2_k127_4385605_3 alginic acid biosynthetic process - - - 0.00000000000001986 85.0
SHD2_k127_4385605_4 CAAX protease self-immunity - - - 0.0002033 46.0
SHD2_k127_4392626_0 helicase involved in DNA repair and perhaps also replication K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 355.0
SHD2_k127_4392626_1 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000000000000000000000005815 203.0
SHD2_k127_4392626_2 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000007098 110.0
SHD2_k127_4397325_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 297.0
SHD2_k127_4397325_1 PFAM peptidase M14 carboxypeptidase A - - - 0.000000000000000000000000000004242 134.0
SHD2_k127_4397325_2 DoxX K15977 - - 0.000000000000000000000000271 111.0
SHD2_k127_4401688_0 Exodeoxyribonuclease III - - - 0.00000000000000000000000000000000000000000000001366 193.0
SHD2_k127_4401688_1 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000009185 88.0
SHD2_k127_4411350_0 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 539.0
SHD2_k127_4411350_1 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 421.0
SHD2_k127_4411350_2 5'-nucleotidase - - - 0.00000000000000000000000000000000004322 149.0
SHD2_k127_4420956_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 292.0
SHD2_k127_4420956_1 Aspartyl protease - - - 0.0000000000000000000000000000000001646 145.0
SHD2_k127_4423980_0 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 2.648e-196 621.0
SHD2_k127_4423980_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 436.0
SHD2_k127_4423980_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 321.0
SHD2_k127_4423980_3 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000006313 212.0
SHD2_k127_4436258_0 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000003323 156.0
SHD2_k127_4436258_1 Belongs to the UPF0761 family K07058 - - 0.0000000000000000000000000000000003848 143.0
SHD2_k127_4436258_2 Yqey-like protein K09117 - - 0.000000000000000000000000000002112 125.0
SHD2_k127_4436258_3 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000001038 121.0
SHD2_k127_4440460_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 2.064e-217 709.0
SHD2_k127_4440460_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000003672 139.0
SHD2_k127_4440460_2 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000004182 138.0
SHD2_k127_4440460_3 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.000000000000000000000000000001095 126.0
SHD2_k127_4440460_4 - - - - 0.0000000000000000007532 89.0
SHD2_k127_4440460_5 Zn-ribbon protein, possibly nucleic acid-binding K07164 - - 0.0000000000000001222 91.0
SHD2_k127_4440460_6 Pyrrolo-quinoline quinone - - - 0.00005266 52.0
SHD2_k127_4440460_7 - - - - 0.0007236 47.0
SHD2_k127_4441137_0 Peptidase family M23 - - - 0.000000000000000000000000000000000000001033 169.0
SHD2_k127_4441137_1 PFAM Fibronectin, type III domain K01179,K06882 - 3.2.1.4 0.000009003 53.0
SHD2_k127_4446074_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 327.0
SHD2_k127_4446074_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000007027 197.0
SHD2_k127_4457057_0 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000003346 212.0
SHD2_k127_4461293_0 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000005881 176.0
SHD2_k127_4461293_1 COG0457 FOG TPR repeat - - - 0.0000000001984 67.0
SHD2_k127_4494057_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000002673 248.0
SHD2_k127_4494057_1 metallopeptidase activity - - - 0.00000000000000001218 96.0
SHD2_k127_4494057_2 FlgD Ig-like domain - - - 0.000002359 60.0
SHD2_k127_45071_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 411.0
SHD2_k127_45071_1 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000007776 172.0
SHD2_k127_45071_2 CAAX amino terminal protease family K07052 - - 0.00000000000000000000000286 113.0
SHD2_k127_4508908_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000006235 250.0
SHD2_k127_4508908_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000001322 234.0
SHD2_k127_4508908_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000001175 223.0
SHD2_k127_4508908_3 Adenylate cyclase - - - 0.00000000000000000007645 100.0
SHD2_k127_4508908_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000009727 93.0
SHD2_k127_4526588_0 PFAM polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 438.0
SHD2_k127_4526588_1 Glycosyltransferase like family 2 K03606,K07011 - - 0.00000000000000000000000000000000000000000000000003058 198.0
SHD2_k127_4526588_2 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000002559 179.0
SHD2_k127_4526588_3 FemAB family - - - 0.00000000000001047 86.0
SHD2_k127_4526588_4 diguanylate cyclase - - - 0.00000000008098 76.0
SHD2_k127_4526588_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000001396 68.0
SHD2_k127_4526588_6 - - - - 0.0000006755 61.0
SHD2_k127_4526588_7 Polysaccharide biosynthesis protein - - - 0.00001475 58.0
SHD2_k127_4541999_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 330.0
SHD2_k127_4541999_1 serine-type peptidase activity K01278,K06889 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000006169 251.0
SHD2_k127_4541999_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000003887 243.0
SHD2_k127_4541999_3 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000001161 149.0
SHD2_k127_4541999_4 - - - - 0.000000000000000002387 93.0
SHD2_k127_4541999_5 - - - - 0.000000000000000002595 98.0
SHD2_k127_4541999_6 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.00000000000000006242 89.0
SHD2_k127_4541999_7 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000001707 79.0
SHD2_k127_4541999_8 SdrD B-like domain - - - 0.000000006921 67.0
SHD2_k127_4542726_0 1,4-alpha-glucan branching enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 406.0
SHD2_k127_4542726_1 spermidine synthase - - - 0.00001959 55.0
SHD2_k127_4566666_0 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 353.0
SHD2_k127_4566666_1 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 351.0
SHD2_k127_4566666_2 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 329.0
SHD2_k127_4566666_3 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 294.0
SHD2_k127_4566666_4 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000005619 168.0
SHD2_k127_4566666_5 Tetratricopeptide repeat - - - 0.000000000000000006565 88.0
SHD2_k127_4566666_6 Psort location CytoplasmicMembrane, score - - - 0.000000000000005691 89.0
SHD2_k127_4566666_7 Tetratricopeptide repeat - - - 0.0000000000008847 78.0
SHD2_k127_4570003_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 1.875e-195 647.0
SHD2_k127_4570003_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 430.0
SHD2_k127_4570003_2 His Kinase A (phosphoacceptor) domain K00694,K03406,K07315,K14986 - 2.4.1.12,2.7.13.3,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 406.0
SHD2_k127_4570003_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 392.0
SHD2_k127_4570003_4 PFAM response regulator receiver - - - 0.000000000000000000000001234 109.0
SHD2_k127_4580068_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 446.0
SHD2_k127_4580068_1 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 431.0
SHD2_k127_4580068_2 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000003764 168.0
SHD2_k127_4580068_3 Glycosyl transferase - - - 0.00000000000000000000000000000000000001649 158.0
SHD2_k127_4580068_4 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000001882 126.0
SHD2_k127_4580068_5 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000003634 124.0
SHD2_k127_4580068_6 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000001852 117.0
SHD2_k127_4580068_7 Putative zinc-finger - - - 0.00000000000009333 74.0
SHD2_k127_4580068_8 C4-type zinc ribbon domain K07164 - - 0.000000005299 62.0
SHD2_k127_4592196_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000008698 150.0
SHD2_k127_4592196_1 lysyltransferase activity K07027 - - 0.00000000000000000000000000007246 128.0
SHD2_k127_4593893_0 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 462.0
SHD2_k127_4593893_1 oligosaccharyl transferase activity - - - 0.0000000000002341 76.0
SHD2_k127_4595217_0 General secretory system II protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 594.0
SHD2_k127_4595217_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 473.0
SHD2_k127_4595217_2 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 451.0
SHD2_k127_4595217_3 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 444.0
SHD2_k127_4595217_4 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001153 257.0
SHD2_k127_4595217_5 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005658 259.0
SHD2_k127_4595217_6 Pfam:N_methyl_2 K02456 - - 0.00000000007669 70.0
SHD2_k127_4595217_7 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000156 69.0
SHD2_k127_4601494_0 spheroidene biosynthetic process - - - 0.0000000000000000000000000000000000000000001582 164.0
SHD2_k127_4601494_1 PFAM amino acid permease-associated region K03294 - - 0.0000000000000000000001563 104.0
SHD2_k127_4601494_2 flagellar protein MotY K21218 - - 0.00007584 55.0
SHD2_k127_4609518_0 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 456.0
SHD2_k127_4609518_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 304.0
SHD2_k127_4609518_2 Heparinase II/III-like protein - - - 0.0000002533 60.0
SHD2_k127_4636318_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000003232 167.0
SHD2_k127_4636318_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000012 138.0
SHD2_k127_4636318_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000004235 113.0
SHD2_k127_4636318_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000003357 81.0
SHD2_k127_4638352_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 519.0
SHD2_k127_4638352_1 lactate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 388.0
SHD2_k127_4638352_2 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000573 223.0
SHD2_k127_4638352_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000004086 105.0
SHD2_k127_4638352_4 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000352 69.0
SHD2_k127_4650380_0 PFAM Abortive infection protein K07052 - - 0.0000000000000000000000000000000000000004148 160.0
SHD2_k127_4650380_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000002134 142.0
SHD2_k127_4650380_2 Aconitase C-terminal domain K01681 GO:0001889,GO:0003674,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006102,GO:0006950,GO:0007275,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0031974,GO:0032501,GO:0032502,GO:0035900,GO:0043167,GO:0043169,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0048513,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0061008,GO:0070013,GO:0071704,GO:0072350 4.2.1.3 0.0000000000000000000000000000001501 124.0
SHD2_k127_4669491_0 serine-type peptidase activity K01303 - 3.4.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 571.0
SHD2_k127_4669491_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 477.0
SHD2_k127_4669966_0 HD domain - - - 0.00000000000000000000000000000000000008113 161.0
SHD2_k127_4676885_0 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 328.0
SHD2_k127_4676885_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001383 268.0
SHD2_k127_4676885_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009743 270.0
SHD2_k127_4676885_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000001393 187.0
SHD2_k127_4676885_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000001359 127.0
SHD2_k127_4676885_5 PspC domain K03973 - - 0.00000000001355 68.0
SHD2_k127_4676885_6 Late embryogenesis abundant protein - - - 0.00008936 55.0
SHD2_k127_4678707_0 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 461.0
SHD2_k127_4678707_1 O-linked GlcNAc transferase - - - 0.00007082 53.0
SHD2_k127_4686507_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 351.0
SHD2_k127_4686507_1 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000000000000000001566 179.0
SHD2_k127_4686507_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000002678 87.0
SHD2_k127_4703938_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 349.0
SHD2_k127_4703938_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000004125 239.0
SHD2_k127_4703938_2 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000000001435 138.0
SHD2_k127_4703938_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000001365 113.0
SHD2_k127_4703938_4 Protein of unknown function (DUF2905) - - - 0.00000000000000003157 85.0
SHD2_k127_4722725_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 622.0
SHD2_k127_4722725_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 384.0
SHD2_k127_4722725_2 coenzyme F420 hydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 379.0
SHD2_k127_4722725_3 2 iron, 2 sulfur cluster binding K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 335.0
SHD2_k127_4722725_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000000000000000000000000000000000006077 177.0
SHD2_k127_4722725_5 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000008627 117.0
SHD2_k127_473432_0 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 379.0
SHD2_k127_473432_1 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000403 150.0
SHD2_k127_4757356_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000009318 278.0
SHD2_k127_4757356_1 AI-2E family transporter - - - 0.00000000000009885 81.0
SHD2_k127_4773065_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 324.0
SHD2_k127_4773065_1 luxR family - - - 0.00003227 57.0
SHD2_k127_4822784_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007533 282.0
SHD2_k127_4822784_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006526 268.0
SHD2_k127_4822784_2 PFAM Adenosine AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.000000000000000000000000000000000000000000000000000003511 213.0
SHD2_k127_4822784_3 - - - - 0.000003766 56.0
SHD2_k127_4824212_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000002284 203.0
SHD2_k127_4824212_1 PFAM CBS domain - - - 0.00000000000000000000001727 117.0
SHD2_k127_4824212_2 PFAM CBS domain - - - 0.00000000000007262 85.0
SHD2_k127_4824212_3 4Fe-4S dicluster domain - - - 0.00000000001409 78.0
SHD2_k127_4827514_0 peptidoglycan turnover K06958,K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000000000000000000000000006491 160.0
SHD2_k127_4827514_2 Acetyltransferase (GNAT) domain - - - 0.0000000000295 75.0
SHD2_k127_4885479_0 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 349.0
SHD2_k127_4885479_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004191 268.0
SHD2_k127_4905037_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 498.0
SHD2_k127_4905037_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000000000000004037 184.0
SHD2_k127_4905037_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000001958 129.0
SHD2_k127_4905037_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000006145 65.0
SHD2_k127_4967300_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 323.0
SHD2_k127_4998479_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000002043 202.0
SHD2_k127_4998479_1 serine acetyltransferase K00640 - 2.3.1.30 0.00000000565 57.0
SHD2_k127_5131872_0 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 332.0
SHD2_k127_5131872_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000001976 169.0
SHD2_k127_513467_0 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000002333 252.0
SHD2_k127_513467_1 Belongs to the UPF0403 family - - - 0.0000000000000000000000000000000000000000000000001127 181.0
SHD2_k127_513467_2 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000003871 128.0
SHD2_k127_518114_0 Berberine and berberine like - - - 4.752e-198 635.0
SHD2_k127_518114_1 ABC transporter, transmembrane K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000003673 225.0
SHD2_k127_523911_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 6.465e-237 758.0
SHD2_k127_523911_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000001855 215.0
SHD2_k127_526382_0 tigr00255 - - - 0.00000000000000000000000000000000000000006704 171.0
SHD2_k127_526382_1 Fibronectin-binding protein - - - 0.00000007398 66.0
SHD2_k127_5288829_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 321.0
SHD2_k127_5288829_1 oxidase subunit - - - 0.0000000000000000000000000544 120.0
SHD2_k127_5292828_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 375.0
SHD2_k127_5292828_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000004719 242.0
SHD2_k127_5292828_10 Recombinase zinc beta ribbon domain - - - 0.0000000958 58.0
SHD2_k127_5292828_11 Recombinase zinc beta ribbon domain K06400 - - 0.0000004238 58.0
SHD2_k127_5292828_2 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000001598 200.0
SHD2_k127_5292828_3 TIGRFAM TonB K03832 - - 0.000000000000000000000000000000004962 137.0
SHD2_k127_5292828_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000003232 125.0
SHD2_k127_5292828_5 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000007244 104.0
SHD2_k127_5292828_6 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000001488 102.0
SHD2_k127_5292828_7 - - - - 0.000000000000000000001851 102.0
SHD2_k127_5292828_8 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000002966 99.0
SHD2_k127_5292828_9 Tetratricopeptide repeat - - - 0.00000000000006527 82.0
SHD2_k127_5293518_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 305.0
SHD2_k127_5293518_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.00000007102 63.0
SHD2_k127_5293518_2 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0001589 49.0
SHD2_k127_5293518_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0003295 51.0
SHD2_k127_5296425_0 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000001318 231.0
SHD2_k127_5296425_1 Hit family K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000004304 176.0
SHD2_k127_5296425_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000001069 97.0
SHD2_k127_5296425_3 LytR cell envelope-related transcriptional attenuator - - - 0.00000008098 59.0
SHD2_k127_5296701_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 396.0
SHD2_k127_5296701_1 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 345.0
SHD2_k127_5296701_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000000000000000003872 128.0
SHD2_k127_5296701_3 - - - - 0.000000000000000000000000005474 111.0
SHD2_k127_5296701_4 HAD-hyrolase-like K07025 - - 0.0000000000000000000000001332 116.0
SHD2_k127_5296701_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000001834 95.0
SHD2_k127_5297738_0 Belongs to the 5'-nucleotidase family K01081,K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 402.0
SHD2_k127_5297738_1 long-chain fatty acid transport protein K06076 - - 0.00000003744 66.0
SHD2_k127_5298017_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000005191 228.0
SHD2_k127_5298017_1 belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000001545 205.0
SHD2_k127_5305180_0 Protein of unknown function (DUF1698) K15257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 364.0
SHD2_k127_5305180_1 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001772 242.0
SHD2_k127_5305180_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000624 104.0
SHD2_k127_5308298_0 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 304.0
SHD2_k127_5308298_1 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000004619 113.0
SHD2_k127_5309122_0 Polysaccharide biosynthesis/export protein - - - 0.000000000000000000000000000000001211 141.0
SHD2_k127_5309122_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000072 130.0
SHD2_k127_5309122_2 Glycosyl transferase 4-like - - - 0.00000000000000000000001521 117.0
SHD2_k127_5309122_3 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00009837 55.0
SHD2_k127_530927_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 613.0
SHD2_k127_530927_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 435.0
SHD2_k127_530927_2 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 439.0
SHD2_k127_530927_3 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000006487 187.0
SHD2_k127_5314665_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000006491 78.0
SHD2_k127_5317573_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 473.0
SHD2_k127_5317573_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 459.0
SHD2_k127_5317573_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000001614 214.0
SHD2_k127_5317573_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000007054 157.0
SHD2_k127_5317573_4 TIGR00268 family K06864 - - 0.0000000000004221 73.0
SHD2_k127_5328135_0 Protein of unknown function (DUF3891) - - - 0.000000000000000000000000000000000000000000000000000000000000000007021 233.0
SHD2_k127_5328135_1 Belongs to the GcvT family K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000003639 174.0
SHD2_k127_5328135_2 chromosome segregation K03497 - - 0.0000000000000000000000000000000001962 143.0
SHD2_k127_5331997_0 Alpha-2-Macroglobulin K06894 - - 0.00000000000000000000000000000000000000000000517 184.0
SHD2_k127_5345850_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000351 207.0
SHD2_k127_5345850_1 biopolymer transport protein - - - 0.0000000000000000000000001756 110.0
SHD2_k127_5345850_2 PFAM Biopolymer transport protein ExbD TolR - - - 0.000000000000000000001167 102.0
SHD2_k127_5345850_3 PBP superfamily domain K02040 - - 0.000000000002389 78.0
SHD2_k127_5345850_4 Tetratricopeptide repeat - - - 0.0000000003809 73.0
SHD2_k127_5345850_5 Evidence 5 No homology to any previously reported sequences - - - 0.00000001305 58.0
SHD2_k127_5347314_0 Belongs to the ABC transporter superfamily K02032,K10823,K12372 - - 0.0000000000000000000000000000000000000000000000000000000000000006756 224.0
SHD2_k127_5347314_1 HD domain K07814 - - 0.0000000002194 70.0
SHD2_k127_5353087_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 475.0
SHD2_k127_5353087_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 360.0
SHD2_k127_5353087_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000004713 180.0
SHD2_k127_5353087_3 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000001331 121.0
SHD2_k127_5353822_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000001423 204.0
SHD2_k127_5354359_0 endonuclease activity K07451 - - 0.000000000000000000000000000000000007505 151.0
SHD2_k127_5354359_1 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000002674 138.0
SHD2_k127_5355619_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 334.0
SHD2_k127_5355619_1 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 304.0
SHD2_k127_5355619_2 Permease YjgP YjgQ K11720 - - 0.000000000000000000000000000000000000000000000000000000166 207.0
SHD2_k127_5355619_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000004821 148.0
SHD2_k127_5355619_4 Belongs to the ComB family K05979 - 3.1.3.71 0.0000000000000000000000000000007453 138.0
SHD2_k127_5355619_5 methyltransferase - - - 0.00000000000001937 83.0
SHD2_k127_5357989_0 ABC-type multidrug transport system ATPase K01990,K16907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003983 259.0
SHD2_k127_5357989_1 AAA domain - - - 0.000000000000000000000000000000000000000000002078 188.0
SHD2_k127_5357989_2 Ser Thr phosphatase family protein K03547 - - 0.000000000000000000000001252 110.0
SHD2_k127_5359800_0 Involved in the biosynthesis of porphyrin-containing compound K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 491.0
SHD2_k127_5359800_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 335.0
SHD2_k127_5359800_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000001414 260.0
SHD2_k127_5359800_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000005891 242.0
SHD2_k127_5375333_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 534.0
SHD2_k127_5379742_0 long-chain fatty acid transport protein - - - 0.00000000003592 73.0
SHD2_k127_5379742_1 Bacterial Ig-like domain (group 3) - - - 0.0000000429 68.0
SHD2_k127_5381487_0 PFAM Aldehyde dehydrogenase family K00128,K00135,K00146,K22187 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79 0.00000000000000000000000000000000000000000000000007913 178.0
SHD2_k127_5381487_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.00000000000000000000000000000000000000000004211 176.0
SHD2_k127_5381487_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000001027 63.0
SHD2_k127_5383510_0 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000002263 211.0
SHD2_k127_5383510_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000001591 192.0
SHD2_k127_5383510_2 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000004986 165.0
SHD2_k127_5383510_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000001193 111.0
SHD2_k127_5383510_4 Cupin domain - - - 0.000000000000000000007533 101.0
SHD2_k127_5388333_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000002422 215.0
SHD2_k127_5388333_1 - - - - 0.0000000000000000000000000004625 121.0
SHD2_k127_5389090_0 ABC transporter transmembrane region K06147 - - 3.961e-216 684.0
SHD2_k127_5389090_1 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000005363 201.0
SHD2_k127_5389844_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.305e-311 973.0
SHD2_k127_5389844_1 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.000000000000000000000000000000001103 146.0
SHD2_k127_5389844_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000004429 102.0
SHD2_k127_5389844_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000007863 85.0
SHD2_k127_5389844_4 transcriptional regulator K01420,K10914 - - 0.00000000000004861 81.0
SHD2_k127_5393174_0 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 347.0
SHD2_k127_5393174_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 309.0
SHD2_k127_5393174_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000001989 234.0
SHD2_k127_5393174_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000001214 170.0
SHD2_k127_5393174_4 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000008375 170.0
SHD2_k127_5393174_5 COG1596 Periplasmic protein involved in polysaccharide export K01991 - - 0.000000000000000002176 95.0
SHD2_k127_5393174_6 Chain length determinant protein - - - 0.000000007759 68.0
SHD2_k127_5397625_0 protein conserved in bacteria K11891 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 368.0
SHD2_k127_5397625_1 type VI secretion protein, VC_A0114 family K11893 - - 0.000000000000000000001155 100.0
SHD2_k127_5397625_2 Type VI secretion system protein DotU K11892 - - 0.0000000000000000008537 96.0
SHD2_k127_539939_0 Dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 416.0
SHD2_k127_5418570_0 membrane - - - 0.0000000000003938 81.0
SHD2_k127_5418570_1 - - - - 0.00000002049 61.0
SHD2_k127_5420051_0 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 322.0
SHD2_k127_5424802_0 Protein export membrane protein K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 356.0
SHD2_k127_5424802_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002612 279.0
SHD2_k127_5424802_2 SecD/SecF GG Motif K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000001438 242.0
SHD2_k127_5424802_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000004802 217.0
SHD2_k127_5424802_4 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000508 128.0
SHD2_k127_5426483_0 Evidence 5 No homology to any previously reported sequences K09607 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004511 282.0
SHD2_k127_5426483_1 cellulase activity K06882 - - 0.00000000000000000000000000000000000000000000000000000000008997 215.0
SHD2_k127_5426483_2 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000005206 182.0
SHD2_k127_5426483_3 cell adhesion involved in biofilm formation - - - 0.00000000000000000007914 98.0
SHD2_k127_5436265_0 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 7.072e-222 700.0
SHD2_k127_5436265_1 PFAM isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 394.0
SHD2_k127_5436265_10 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000007201 135.0
SHD2_k127_5436265_11 TPM domain K08988 - - 0.0000000000000000000000000000000001034 148.0
SHD2_k127_5436265_12 Lysin motif - - - 0.0000000000000000006451 90.0
SHD2_k127_5436265_13 - - - - 0.00000000000000001283 92.0
SHD2_k127_5436265_14 Redoxin K03564 - 1.11.1.15 0.000000000006032 76.0
SHD2_k127_5436265_15 - - - - 0.000000001518 66.0
SHD2_k127_5436265_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006834 248.0
SHD2_k127_5436265_3 COG0006 Xaa-Pro aminopeptidase K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000003605 240.0
SHD2_k127_5436265_4 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000001458 224.0
SHD2_k127_5436265_5 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000006572 202.0
SHD2_k127_5436265_6 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000006756 173.0
SHD2_k127_5436265_7 TPM domain K06872 - - 0.00000000000000000000000000000000000000001518 165.0
SHD2_k127_5436265_8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000001271 149.0
SHD2_k127_5436265_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000006301 158.0
SHD2_k127_5450014_0 PFAM ABC transporter related K02049,K15555,K15578 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 431.0
SHD2_k127_5450014_1 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003896 276.0
SHD2_k127_5457170_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000001681 196.0
SHD2_k127_5457170_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000003107 128.0
SHD2_k127_5457170_2 Belongs to the UPF0102 family K07460 - - 0.000000002074 66.0
SHD2_k127_5463380_0 Immune inhibitor A peptidase M6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000009528 248.0
SHD2_k127_5465263_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000005763 238.0
SHD2_k127_5465263_1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000007632 206.0
SHD2_k127_5465263_2 PFAM pentapeptide repeat protein - - - 0.0000000000000000003776 102.0
SHD2_k127_5471539_0 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 6.265e-257 812.0
SHD2_k127_5471539_1 Glycosyl hydrolases family 15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 439.0
SHD2_k127_5471539_2 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 356.0
SHD2_k127_5478559_0 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000003203 185.0
SHD2_k127_5478559_1 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000001323 190.0
SHD2_k127_5478559_2 Ami_3 K01448 - 3.5.1.28 0.0001016 54.0
SHD2_k127_5494513_0 peptide catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 385.0
SHD2_k127_5494513_1 PFAM Fibronectin type III domain - - - 0.00000000000000000000000007481 113.0
SHD2_k127_5496153_0 - - - - 0.0007416 52.0
SHD2_k127_5503030_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 481.0
SHD2_k127_5503030_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 351.0
SHD2_k127_5503030_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 312.0
SHD2_k127_5503030_3 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000009853 236.0
SHD2_k127_5503030_4 PFAM CMP dCMP deaminase zinc-binding K01489 - 3.5.4.5 0.00000000000000006083 95.0
SHD2_k127_5506040_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000001763 168.0
SHD2_k127_5506040_1 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000003016 150.0
SHD2_k127_5506040_2 Cytochrome c - - - 0.0000000000002586 83.0
SHD2_k127_5509193_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.0 1465.0
SHD2_k127_5509193_1 PFAM Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 573.0
SHD2_k127_5509193_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 399.0
SHD2_k127_5509193_3 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 382.0
SHD2_k127_5509193_4 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003291 309.0
SHD2_k127_5513252_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 482.0
SHD2_k127_5513252_1 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000001751 109.0
SHD2_k127_5519305_0 PFAM peptidase M6, immune inhibitor A - - - 0.0000000000000000000000000000000000000000000000000000000000000002072 244.0
SHD2_k127_5519305_1 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000000000001533 159.0
SHD2_k127_5519305_2 - - - - 0.0000104 57.0
SHD2_k127_5519305_3 domain protein K20276 - - 0.0000361 56.0
SHD2_k127_5519305_4 - - - - 0.0005626 51.0
SHD2_k127_5525184_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 373.0
SHD2_k127_5525184_1 KDPG and KHG aldolase - - - 0.0000000000000000000000000000000000001253 154.0
SHD2_k127_5525184_2 cellulose binding - - - 0.000000001777 67.0
SHD2_k127_5544438_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 421.0
SHD2_k127_5544438_1 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 310.0
SHD2_k127_5544438_2 Peptidase family M3 K01392 - 3.4.24.15 0.000000000000000000000000000000000000000000000000000000000000000224 223.0
SHD2_k127_5544438_3 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000000000000000002872 174.0
SHD2_k127_5544438_4 Domain of unknown function (DUF4386) - - - 0.000007015 52.0
SHD2_k127_5545119_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 475.0
SHD2_k127_5545119_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 362.0
SHD2_k127_5545119_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000001187 130.0
SHD2_k127_5545119_3 PFAM NADH-ubiquinone plastoquinone oxidoreductase, chain 6 K00339 - 1.6.5.3 0.0000000000000000000000006123 110.0
SHD2_k127_5545119_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000016 113.0
SHD2_k127_5563917_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 297.0
SHD2_k127_5563917_1 iron ion homeostasis K03709,K04758 - - 0.00000000000000000000000000000000000000000002917 173.0
SHD2_k127_5563917_2 Transcriptional regulator - - - 0.000000000000000000000001064 109.0
SHD2_k127_5641853_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 322.0
SHD2_k127_5641853_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008312 278.0
SHD2_k127_5641853_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000001472 102.0
SHD2_k127_5641853_3 Glycosyl transferase family 2 - - - 0.0000000000000000002549 94.0
SHD2_k127_5641853_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000002914 64.0
SHD2_k127_5652300_0 Subtilase family - - - 0.000000000000000000000000000000004619 147.0
SHD2_k127_5652300_1 Belongs to the peptidase S8 family K13276,K17734 - - 0.000000000000002652 90.0
SHD2_k127_5654602_0 photosystem II stabilization K02237 - - 0.00000000000000000000000000000002863 133.0
SHD2_k127_5654602_1 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000000003201 139.0
SHD2_k127_5667890_0 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001418 276.0
SHD2_k127_5667890_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000009524 96.0
SHD2_k127_5667890_2 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000002004 83.0
SHD2_k127_5670777_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.072e-203 647.0
SHD2_k127_5670777_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 421.0
SHD2_k127_5670777_2 Immune inhibitor A peptidase M6 - - - 0.00000000002686 72.0
SHD2_k127_5675957_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 468.0
SHD2_k127_5675957_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000002398 181.0
SHD2_k127_5680930_0 Reprolysin (M12B) family zinc metalloprotease - - - 0.00000000000000000000000002852 124.0
SHD2_k127_56827_0 cellulose binding - - - 0.000000000000000000003009 108.0
SHD2_k127_5689031_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 383.0
SHD2_k127_5689031_1 maltose binding K02027,K17329 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 377.0
SHD2_k127_5689031_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001655 283.0
SHD2_k127_5689031_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.0000000000000000000000000000005655 127.0
SHD2_k127_5708601_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 454.0
SHD2_k127_5708601_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 410.0
SHD2_k127_5713752_0 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 334.0
SHD2_k127_5713752_1 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 322.0
SHD2_k127_5713752_2 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000003426 213.0
SHD2_k127_5713752_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000001206 209.0
SHD2_k127_5713752_4 DinB family - - - 0.0000000000000000000000000000000000000000000000002565 186.0
SHD2_k127_5713752_5 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000002293 140.0
SHD2_k127_5713752_6 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000000000514 135.0
SHD2_k127_5713752_7 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 0.000000001419 70.0
SHD2_k127_5722707_0 PFAM Cation efflux - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 323.0
SHD2_k127_5722707_1 BON domain - - - 0.0000000000000008888 87.0
SHD2_k127_5722707_2 Thioredoxin - - - 0.000001143 58.0
SHD2_k127_5728875_0 Transcriptional regulator with HTH domain and aminotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 368.0
SHD2_k127_5728875_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 309.0
SHD2_k127_5769546_0 guanyl-nucleotide exchange factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 443.0
SHD2_k127_5769546_1 COG1305 Transglutaminase-like enzymes - - - 0.00000000000000000000002653 107.0
SHD2_k127_5769546_2 - - - - 0.000000000002741 80.0
SHD2_k127_5771513_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 614.0
SHD2_k127_5771513_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001516 274.0
SHD2_k127_5771513_2 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000001769 268.0
SHD2_k127_577724_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.988e-231 727.0
SHD2_k127_577724_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 9.806e-205 666.0
SHD2_k127_577724_2 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009665 275.0
SHD2_k127_577724_3 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000472 275.0
SHD2_k127_577724_4 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000000000000000000000000000000000000000000000000000000002154 215.0
SHD2_k127_577724_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000006176 130.0
SHD2_k127_577724_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000006207 126.0
SHD2_k127_5781991_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 512.0
SHD2_k127_5781991_1 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 312.0
SHD2_k127_5781991_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000158 225.0
SHD2_k127_5781991_3 Phospholipid methyltransferase - - - 0.00000000000001951 81.0
SHD2_k127_5783556_0 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 530.0
SHD2_k127_5783556_1 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 379.0
SHD2_k127_5783556_2 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 331.0
SHD2_k127_5783556_3 - - - - 0.000000000000000000000000000000000001293 148.0
SHD2_k127_5786518_0 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004364 282.0
SHD2_k127_5786518_1 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000002762 195.0
SHD2_k127_5790191_0 lipid kinase activity - - - 0.0000000000000000000000000000000000000000000002419 180.0
SHD2_k127_5790191_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000001664 148.0
SHD2_k127_5790191_2 PFAM Phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.0000000000000000000000000000004638 131.0
SHD2_k127_5790191_3 Conserved repeat domain - - - 0.000000000000000000000618 112.0
SHD2_k127_5790191_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000001041 86.0
SHD2_k127_5802118_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003131 295.0
SHD2_k127_5802118_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000005026 147.0
SHD2_k127_5805120_0 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003632 270.0
SHD2_k127_5805120_1 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000000000000000000000000101 209.0
SHD2_k127_5805120_2 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000623 151.0
SHD2_k127_5805120_3 radical SAM domain protein - - - 0.00000000000000000000001816 113.0
SHD2_k127_580556_0 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000008579 112.0
SHD2_k127_5809665_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 335.0
SHD2_k127_5809665_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000005935 145.0
SHD2_k127_5836230_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 476.0
SHD2_k127_5836230_1 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 324.0
SHD2_k127_5836230_2 Type IV pilus biogenesis stability protein PilW - - - 0.0000783 55.0
SHD2_k127_5842122_0 - - - - 0.0000000000000000000000000000000000000009795 163.0
SHD2_k127_5846996_0 TIGRFAM Flagellar hook-associated protein, FlgK K02396 - - 0.000000000000000000000000000000000000000000000000000000001283 218.0
SHD2_k127_5846996_1 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000000000007914 186.0
SHD2_k127_5851649_0 ECF sigma factor K03088 - - 0.0000000000000000000000000316 117.0
SHD2_k127_5851649_1 YceI-like domain - - - 0.0000000000000007998 85.0
SHD2_k127_5852102_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000005083 164.0
SHD2_k127_5860403_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 421.0
SHD2_k127_5860403_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 329.0
SHD2_k127_5860403_2 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000009272 150.0
SHD2_k127_5860403_3 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000006645 88.0
SHD2_k127_5870627_0 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 601.0
SHD2_k127_5870627_1 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 325.0
SHD2_k127_5881421_0 Pyrophosphatase K06019 - 3.6.1.1 0.0000000000000000000000000007286 123.0
SHD2_k127_5881421_1 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000005713 53.0
SHD2_k127_5927068_0 Polysaccharide biosynthesis protein K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 332.0
SHD2_k127_5927068_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002923 278.0
SHD2_k127_5929306_0 Protein of unknown function (DUF2400) K10773 - 4.2.99.18 0.0000000000000000000000000001777 124.0
SHD2_k127_5929306_1 Glycosyl transferase family 21 - - - 0.0000000000000000000004554 108.0
SHD2_k127_5956291_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 603.0
SHD2_k127_5956291_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 436.0
SHD2_k127_5956291_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 341.0
SHD2_k127_5956291_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000008542 169.0
SHD2_k127_5956291_4 - - - - 0.000000002934 70.0
SHD2_k127_5975658_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 405.0
SHD2_k127_5975658_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 302.0
SHD2_k127_5975658_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000001399 217.0
SHD2_k127_5975658_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K00627,K01571,K02160 - 2.3.1.12,4.1.1.3 0.0000000000000000000000000000000000000005507 153.0
SHD2_k127_5998787_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001707 287.0
SHD2_k127_6022764_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.047e-232 730.0
SHD2_k127_6022764_1 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.00000000000000000000000000000000000000001425 165.0
SHD2_k127_6022764_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000002489 130.0
SHD2_k127_6026669_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000000000000000000000000006744 160.0
SHD2_k127_6026669_1 polysaccharide export K01991 - - 0.00000000000000000000000000000003124 145.0
SHD2_k127_6049575_0 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 379.0
SHD2_k127_6049575_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 317.0
SHD2_k127_60671_0 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 440.0
SHD2_k127_60671_1 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 346.0
SHD2_k127_60671_2 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000005021 219.0
SHD2_k127_60671_3 Domain of unknown function (DUF4142) - - - 0.000000000000000000000000000000005639 139.0
SHD2_k127_60671_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000002359 68.0
SHD2_k127_60671_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000002534 76.0
SHD2_k127_60671_6 Membrane - - - 0.0002117 51.0
SHD2_k127_6074741_0 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000001057 131.0
SHD2_k127_6074741_1 Domain of unknown function (DUF4386) - - - 0.0000000000000000005815 97.0
SHD2_k127_6074741_2 Domain of unknown function (DUF4386) - - - 0.0000001142 59.0
SHD2_k127_6085558_0 B12 binding domain K00548 - 2.1.1.13 0.0 1146.0
SHD2_k127_6085558_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.000000000000000000000002243 106.0
SHD2_k127_6141464_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008335 295.0
SHD2_k127_6141464_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000001232 253.0
SHD2_k127_6149445_0 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000003528 195.0
SHD2_k127_6149445_1 Tetratricopeptide repeat - - - 0.0000000000000005241 91.0
SHD2_k127_6149445_2 CUB and sushi K17495 - - 0.00002678 49.0
SHD2_k127_6192533_0 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000002143 136.0
SHD2_k127_6192533_1 Carbon-nitrogen hydrolase - - - 0.0000000006178 69.0
SHD2_k127_6257598_0 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 347.0
SHD2_k127_6257598_1 PFAM PKD domain containing protein - - - 0.0000000000005005 82.0
SHD2_k127_6272767_0 Belongs to the glycosyl hydrolase 13 family K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 310.0
SHD2_k127_6343486_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000001471 149.0
SHD2_k127_6343486_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.0000000003422 74.0
SHD2_k127_6351533_0 translation release factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 360.0
SHD2_k127_6351533_1 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000002715 181.0
SHD2_k127_6351533_2 Belongs to the arylamine N-acetyltransferase family K00675,K15466 - 2.3.1.118 0.000006659 57.0
SHD2_k127_6356762_0 RTX toxins and related Ca2 binding proteins - - - 0.000000000000000000000000005171 125.0
SHD2_k127_6357484_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 409.0
SHD2_k127_6357484_1 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000476 235.0
SHD2_k127_6358883_0 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000001058 160.0
SHD2_k127_6358883_1 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000002697 103.0
SHD2_k127_6358883_2 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0003502 49.0
SHD2_k127_6361598_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 507.0
SHD2_k127_6361598_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 368.0
SHD2_k127_6361598_2 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000007461 203.0
SHD2_k127_6361598_3 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000009231 164.0
SHD2_k127_6363356_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 490.0
SHD2_k127_6363356_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 404.0
SHD2_k127_6363356_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 326.0
SHD2_k127_6363356_3 amino acid activation for nonribosomal peptide biosynthetic process K06045 - 4.2.1.129,5.4.99.17 0.00000000000002297 86.0
SHD2_k127_6363356_4 exo-alpha-(2->6)-sialidase activity - - - 0.000000000007581 81.0
SHD2_k127_6367211_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 418.0
SHD2_k127_6367211_1 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000001135 229.0
SHD2_k127_6370539_0 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009198 432.0
SHD2_k127_6370539_1 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.000000000000000000000000000000000001089 161.0
SHD2_k127_6372701_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 0.0 1208.0
SHD2_k127_6372701_1 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000004786 135.0
SHD2_k127_6372701_2 COG1226 Kef-type K transport systems - - - 0.000000000000000000000000000000008734 139.0
SHD2_k127_6374510_0 COG1192 ATPases involved in chromosome partitioning K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.000000000000000000000000000000000000000000000000008405 194.0
SHD2_k127_6374510_1 chlorophyll binding - - - 0.000000000000000000000000000000000002141 146.0
SHD2_k127_6377647_0 PhoD-like phosphatase - - - 0.0000000000000000000000000000000000000000000004322 184.0
SHD2_k127_6382544_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004133 279.0
SHD2_k127_6382544_1 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000002064 232.0
SHD2_k127_6385471_0 Alcohol dehydrogenase GroES-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 562.0
SHD2_k127_6385471_1 Cyclase dehydrase - - - 0.00000000000000000000000000000000000000000000000000000000000007459 224.0
SHD2_k127_6385471_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000002731 149.0
SHD2_k127_6385471_3 Psort location OuterMembrane, score - - - 0.0000000002608 68.0
SHD2_k127_6386315_0 Lamin Tail Domain K07004 - - 0.0000000000000000000000000000000000000000000009801 186.0
SHD2_k127_6386315_1 - - - - 0.00000000000000000000000000000000000000006521 172.0
SHD2_k127_6386315_2 Evidence 5 No homology to any previously reported sequences K01083,K01729,K12287 - 3.1.3.8,4.2.2.3 0.00000000000000000000000000000004548 144.0
SHD2_k127_6386315_3 metallopeptidase activity - - - 0.000000000007432 78.0
SHD2_k127_6388157_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 540.0
SHD2_k127_6388157_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 429.0
SHD2_k127_6388157_2 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 385.0
SHD2_k127_6388157_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004698 278.0
SHD2_k127_6388157_4 major pilin protein fima - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002135 295.0
SHD2_k127_6388157_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000003776 224.0
SHD2_k127_6388157_6 water channel activity K02440,K06188,K09874 - - 0.00000000000000000000000000000000000000000000000000003816 196.0
SHD2_k127_6388157_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000008891 198.0
SHD2_k127_6392092_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000001168 81.0
SHD2_k127_6393256_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000007609 177.0
SHD2_k127_6393256_1 Competence protein - GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000001741 89.0
SHD2_k127_6394449_0 Trypsin-like serine protease K01337 - 3.4.21.50 0.00000000000000000000000000233 130.0
SHD2_k127_6394449_1 polysaccharide catabolic process K01179,K01218 - 3.2.1.4,3.2.1.78 0.000000000000002133 91.0
SHD2_k127_6394668_0 RelA SpoT domain protein - - - 0.00000000000000000000000000000000000000000000000000001406 199.0
SHD2_k127_6394668_1 Belongs to the peptidase S11 family K01286,K07258,K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 0.00000000000000000000000000000000000000000000000002241 194.0
SHD2_k127_6394668_2 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000004256 196.0
SHD2_k127_6394668_3 Could be involved in septation K06412 - - 0.00000000000002608 79.0
SHD2_k127_6400152_0 pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000001713 264.0
SHD2_k127_6400152_1 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.0000000000000000000000000000000000005251 153.0
SHD2_k127_6400152_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000003648 108.0
SHD2_k127_6400541_0 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000005834 52.0
SHD2_k127_6400541_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000004154 56.0
SHD2_k127_6403645_0 PFAM NHL repeat containing protein - - - 0.000000000000000000003887 108.0
SHD2_k127_6403645_1 - - - - 0.000000000002195 73.0
SHD2_k127_6403744_0 Tetratricopeptide repeat - - - 0.00000000000000000000000003825 122.0
SHD2_k127_6403744_1 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000971 119.0
SHD2_k127_6403744_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000001475 65.0
SHD2_k127_6403744_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.000002047 60.0
SHD2_k127_6403744_5 Belongs to the peptidase S8 family - - - 0.00005925 55.0
SHD2_k127_6403744_6 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00008039 50.0
SHD2_k127_6404689_0 PFAM malic K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 509.0
SHD2_k127_6404689_1 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003884 244.0
SHD2_k127_6409337_0 domain protein K20276 - - 0.0000000000000003367 92.0
SHD2_k127_6415817_0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000009022 190.0
SHD2_k127_6415817_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000001287 164.0
SHD2_k127_6415817_2 transcription antitermination K03625 - - 0.00000000000000000000001685 104.0
SHD2_k127_6423632_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 570.0
SHD2_k127_6423632_1 repeat-containing protein - - - 0.00000000000000000000000749 111.0
SHD2_k127_6423632_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000001251 96.0
SHD2_k127_6423632_3 Protein of unknown function (DUF3426) - - - 0.0000006864 51.0
SHD2_k127_6425517_0 metallopeptidase activity K03592 - - 0.0000000000000000000000000000001287 136.0
SHD2_k127_6432576_0 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 460.0
SHD2_k127_6432576_1 Belongs to the metal hydrolase YfiT family - - - 0.0000000000000000000000000000000004805 133.0
SHD2_k127_6437075_0 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 361.0
SHD2_k127_6437075_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 336.0
SHD2_k127_6437075_2 Ribosomal subunit interface protein - - - 0.000000000000000000000002026 106.0
SHD2_k127_6437367_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 403.0
SHD2_k127_6437367_1 PFAM SpoVR like protein K06415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 359.0
SHD2_k127_6440550_0 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 342.0
SHD2_k127_6440550_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000003814 264.0
SHD2_k127_6440550_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000125 227.0
SHD2_k127_6441455_0 Amino acid permease - - - 2.157e-246 779.0
SHD2_k127_6441455_1 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 361.0
SHD2_k127_6441455_2 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 291.0
SHD2_k127_6441455_3 - - - - 0.0000000000571 75.0
SHD2_k127_6441455_4 ATP-grasp domain - - - 0.000000001093 60.0
SHD2_k127_6441455_5 - - - - 0.00006537 55.0
SHD2_k127_6442806_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 417.0
SHD2_k127_6442806_1 PFAM Protein-tyrosine phosphatase, low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000000002418 104.0
SHD2_k127_6442806_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00008874 46.0
SHD2_k127_6443691_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003863 276.0
SHD2_k127_6443691_1 Predicted membrane protein (DUF2207) - - - 0.000000000000000000003869 96.0
SHD2_k127_6444000_0 xanthine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 346.0
SHD2_k127_6444000_1 protease IV K04773 - - 0.0000000000000000000000000000000000000000006597 172.0
SHD2_k127_6461495_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 6.041e-213 672.0
SHD2_k127_6461495_1 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000003141 203.0
SHD2_k127_6461495_2 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000001456 137.0
SHD2_k127_6461495_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000006312 122.0
SHD2_k127_6461495_4 Tetratricopeptide repeat - - - 0.00002052 58.0
SHD2_k127_6462596_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 2.647e-251 786.0
SHD2_k127_6475341_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 474.0
SHD2_k127_6475341_1 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002909 270.0
SHD2_k127_6475341_2 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000002472 115.0
SHD2_k127_6483408_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 515.0
SHD2_k127_6483408_1 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 309.0
SHD2_k127_6485706_0 Peptidase, M16 K07263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 1.079e-232 753.0
SHD2_k127_6485706_1 Type II secretory pathway component ExeA K02450 - - 0.000000000000000000000000000000000007698 141.0
SHD2_k127_6493885_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 517.0
SHD2_k127_6493885_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000008097 244.0
SHD2_k127_6493885_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000001361 184.0
SHD2_k127_6493885_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000005859 170.0
SHD2_k127_6493885_4 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000006028 117.0
SHD2_k127_6495382_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 422.0
SHD2_k127_6495382_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003758 259.0
SHD2_k127_6495382_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000529 198.0
SHD2_k127_6495382_3 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 0.000000000000000000000000004904 124.0
SHD2_k127_6495382_4 Iron-binding zinc finger CDGSH type K06886 - - 0.00000000000001646 75.0
SHD2_k127_6499051_0 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 370.0
SHD2_k127_6499051_1 With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.000000000000000000000000000000000000000000000000000000008308 206.0
SHD2_k127_6510584_0 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 309.0
SHD2_k127_6510584_1 Proton-conducting membrane transporter - - - 0.000001469 53.0
SHD2_k127_6523318_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 5.601e-223 706.0
SHD2_k127_6523318_1 Cold shock protein K03704 - - 0.0000000000000000000000002017 106.0
SHD2_k127_6523318_2 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000002965 112.0
SHD2_k127_65434_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.074e-206 665.0
SHD2_k127_65434_1 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 419.0
SHD2_k127_65434_2 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003415 271.0
SHD2_k127_65434_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000001245 118.0
SHD2_k127_65434_4 SprA protein - - - 0.00000000006862 76.0
SHD2_k127_65434_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000009158 64.0
SHD2_k127_65434_6 Protein of unknown function (DUF503) K09764 - - 0.000000001545 65.0
SHD2_k127_6560757_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 597.0
SHD2_k127_6560757_1 NADH ubiquinone oxidoreductase, 20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 315.0
SHD2_k127_6560757_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000008991 139.0
SHD2_k127_6564658_0 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 355.0
SHD2_k127_6564658_1 FlgD Ig-like domain K15924 - 3.2.1.136 0.00000000000004352 87.0
SHD2_k127_6580774_0 Natural resistance-associated macrophage protein K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 447.0
SHD2_k127_6580774_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 359.0
SHD2_k127_6580774_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 317.0
SHD2_k127_6580774_3 metallopeptidase activity K06402 - - 0.00000000000000000000000000000000000000000000000000000000009522 212.0
SHD2_k127_6580774_4 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000001769 186.0
SHD2_k127_6580774_5 Tetratricopeptide repeat - - - 0.000000001918 64.0
SHD2_k127_6585205_0 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 321.0
SHD2_k127_6585205_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000008468 117.0
SHD2_k127_6593349_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 1.285e-213 671.0
SHD2_k127_6593349_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 400.0
SHD2_k127_6593349_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 394.0
SHD2_k127_6593349_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000002392 129.0
SHD2_k127_6593349_4 Binds the 23S rRNA K02909 - - 0.00000000000000000000000009123 120.0
SHD2_k127_6593349_5 PFAM Tetratricopeptide repeat - - - 0.0008284 51.0
SHD2_k127_6593917_0 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 332.0
SHD2_k127_6607419_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 4.175e-301 944.0
SHD2_k127_6607419_1 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17723,K17828 - 1.3.1.1,1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002411 285.0
SHD2_k127_6607419_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000000000000001043 159.0
SHD2_k127_6607419_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000006025 155.0
SHD2_k127_6610906_0 PFAM Cytochrome b b6 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 578.0
SHD2_k127_6610906_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 404.0
SHD2_k127_6610906_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 324.0
SHD2_k127_6610906_3 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000002988 149.0
SHD2_k127_6611816_0 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000005005 230.0
SHD2_k127_6611816_1 Belongs to the peptidase S8 family K01280 - 3.4.14.10 0.0000000000000000000000000000000000002627 158.0
SHD2_k127_6635781_0 PFAM Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 557.0
SHD2_k127_6635781_1 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.000408 43.0
SHD2_k127_6636018_0 curli production assembly transport component CsgG K04087 - - 0.00000000000000000000000000000381 135.0
SHD2_k127_6655675_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 GO:0000096,GO:0000098,GO:0000166,GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006556,GO:0006732,GO:0006790,GO:0006807,GO:0007275,GO:0007568,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0008340,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009087,GO:0009108,GO:0009314,GO:0009416,GO:0009628,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0010243,GO:0010259,GO:0010883,GO:0010888,GO:0014070,GO:0014074,GO:0016043,GO:0016054,GO:0016363,GO:0016597,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0022607,GO:0030554,GO:0031406,GO:0031974,GO:0031981,GO:0032259,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032991,GO:0034097,GO:0034214,GO:0034399,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046500,GO:0046683,GO:0046872,GO:0046983,GO:0048269,GO:0048511,GO:0048519,GO:0048856,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0051591,GO:0051716,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071310,GO:0071345,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0098601,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1902494,GO:1905952,GO:1905953,GO:1990234,GO:1990823,GO:1990830 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 408.0
SHD2_k127_6655675_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 369.0
SHD2_k127_6655675_2 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000616 196.0
SHD2_k127_665976_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 617.0
SHD2_k127_6675455_0 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 417.0
SHD2_k127_6675455_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 419.0
SHD2_k127_6675455_10 HlyD membrane-fusion protein of T1SS K01993 - - 0.000000000000000000000000000000000000000000000000000000006768 212.0
SHD2_k127_6675455_11 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000001598 200.0
SHD2_k127_6675455_12 repeat-containing protein - - - 0.00000000000000000000000000003514 134.0
SHD2_k127_6675455_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 385.0
SHD2_k127_6675455_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 375.0
SHD2_k127_6675455_4 Sterol carrier protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 362.0
SHD2_k127_6675455_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 329.0
SHD2_k127_6675455_6 transport, permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 320.0
SHD2_k127_6675455_7 transport, permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 319.0
SHD2_k127_6675455_8 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001263 283.0
SHD2_k127_6675455_9 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000001166 248.0
SHD2_k127_6681894_0 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000001047 191.0
SHD2_k127_6681894_1 - - - - 0.000000000000000000000000000000003518 130.0
SHD2_k127_6681894_2 Protein of unknown function (DUF433) - - - 0.00000000000000000000004889 99.0
SHD2_k127_6683514_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 312.0
SHD2_k127_6683514_1 lyase activity - - - 0.00000000000000000000000000000000000000000000000004121 199.0
SHD2_k127_6689190_0 protein conserved in bacteria K11896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 494.0
SHD2_k127_6689190_1 Gene 25-like lysozyme - - - 0.0000000000000000002438 90.0
SHD2_k127_6721889_0 Acetokinase family K00925 - 2.7.2.1 0.000000000000000000000000004075 116.0
SHD2_k127_6721889_1 SMART Tetratricopeptide domain protein - - - 0.000000000000006101 86.0
SHD2_k127_6722848_0 Belongs to the carbamoyltransferase HypF family K04656 - - 9.077e-220 699.0
SHD2_k127_67247_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 391.0
SHD2_k127_67247_1 Protein of unknown function (DUF523) K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000919 174.0
SHD2_k127_67247_2 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000279 147.0
SHD2_k127_67247_3 CoA binding domain K06929 - - 0.00000000000000000000000000001505 121.0
SHD2_k127_67247_4 - - - - 0.000000000000000001956 87.0
SHD2_k127_6736538_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00207,K12527,K17723 - 1.3.1.1,1.3.1.2,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 451.0
SHD2_k127_6742372_0 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 364.0
SHD2_k127_6742372_1 PTS system K02795 - - 0.0002475 49.0
SHD2_k127_6743127_0 Fis Family K02584 - - 0.000000000000000000000000000000000000004493 154.0
SHD2_k127_6745677_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 357.0
SHD2_k127_6745677_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 314.0
SHD2_k127_6745677_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002312 260.0
SHD2_k127_6745677_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000003799 220.0
SHD2_k127_6745677_4 - - - - 0.000000000000000000000000000000000000000000000000000000003259 208.0
SHD2_k127_6745677_5 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000007432 160.0
SHD2_k127_6745677_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000001083 82.0
SHD2_k127_675083_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 308.0
SHD2_k127_675083_1 glucosamine-1-phosphate N-acetyltransferase activity K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000002399 285.0
SHD2_k127_6757855_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 392.0
SHD2_k127_6757855_1 PFAM Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 350.0
SHD2_k127_6757855_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000005805 122.0
SHD2_k127_6757855_3 ABC transporter K02003 - - 0.000000000000000000002853 95.0
SHD2_k127_6758911_0 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000005294 231.0
SHD2_k127_6758911_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000001187 183.0
SHD2_k127_6758911_2 Outer membrane lipoprotein - - - 0.00000000000000000000000000007331 121.0
SHD2_k127_6759275_0 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 501.0
SHD2_k127_6759275_1 RnfC Barrel sandwich hybrid domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001663 254.0
SHD2_k127_6765645_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 4.328e-198 642.0
SHD2_k127_6765645_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 367.0
SHD2_k127_6765645_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000002927 195.0
SHD2_k127_6765645_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000004389 177.0
SHD2_k127_6765645_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000008365 69.0
SHD2_k127_6765645_5 antibiotic catabolic process - - - 0.000009336 58.0
SHD2_k127_6768052_0 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000001504 222.0
SHD2_k127_6768052_1 9-O-acetylesterase K05970 - 3.1.1.53 0.000000000001221 72.0
SHD2_k127_6768052_2 peptidase activity, acting on L-amino acid peptides - - - 0.00003934 46.0
SHD2_k127_6771668_0 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005307 279.0
SHD2_k127_6771668_1 Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000006879 247.0
SHD2_k127_6771668_2 TfoX N-terminal domain - - - 0.00004913 55.0
SHD2_k127_6771668_3 Intracellular proteinase inhibitor - - - 0.0005457 52.0
SHD2_k127_6774351_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008647 355.0
SHD2_k127_6774351_1 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000001781 188.0
SHD2_k127_6774351_2 B3/4 domain - - - 0.0000000000000000000000000000000000000000000000005455 182.0
SHD2_k127_6776251_0 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 331.0
SHD2_k127_6776251_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000037 66.0
SHD2_k127_6789653_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 549.0
SHD2_k127_6789653_1 PFAM helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 495.0
SHD2_k127_6789653_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005547 265.0
SHD2_k127_6789653_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000001295 254.0
SHD2_k127_6789653_4 Hsp33 protein K04083 - - 0.000000000000000000000000000000000000000000000003972 182.0
SHD2_k127_6789653_5 Tetratricopeptide repeat - - - 0.000000000004158 77.0
SHD2_k127_6789653_6 - - - - 0.00000004173 65.0
SHD2_k127_6808_0 cytochrome c nitrite reductase K15876 - - 0.00000000000000000000000000000000000000000000000000001964 192.0
SHD2_k127_6808_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000002796 138.0
SHD2_k127_6808_2 Belongs to the peptidase S8 family K13276,K17734 - - 0.00000000000000000000052 113.0
SHD2_k127_6808_3 protein secretion K08651 - 3.4.21.66 0.0000000000000001755 94.0
SHD2_k127_6818372_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0000000000000000000000000000000000000000000002126 169.0
SHD2_k127_6818372_1 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000007831 160.0
SHD2_k127_6818372_2 Protein of unknown function (DUF3347) - - - 0.000000000005067 75.0
SHD2_k127_6820516_0 CheD chemotactic sensory transduction K03411 - 3.5.1.44 0.000000000000000000000000000000000005956 141.0
SHD2_k127_6820516_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000009894 123.0
SHD2_k127_6820516_2 GGDEF domain K03413 - - 0.0000000000000000000001363 105.0
SHD2_k127_6820516_3 Chemotaxis phosphatase CheX - - - 0.0006346 50.0
SHD2_k127_6826454_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 383.0
SHD2_k127_6826454_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 342.0
SHD2_k127_6826454_2 Cation transport regulator - - - 0.000000000000000000000000000000000000000000000000007331 188.0
SHD2_k127_6826454_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000001533 145.0
SHD2_k127_6826454_4 beta-galactosidase activity K01190 - 3.2.1.23 0.00000115 60.0
SHD2_k127_6829225_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000007163 89.0
SHD2_k127_6829225_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000002371 60.0
SHD2_k127_6832346_0 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 411.0
SHD2_k127_6838259_0 PFAM sigma-54 factor interaction domain-containing protein K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 396.0
SHD2_k127_6838259_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 294.0
SHD2_k127_6838259_2 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000006558 217.0
SHD2_k127_6838259_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000002989 187.0
SHD2_k127_6838259_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000002457 156.0
SHD2_k127_6838259_5 OsmC-like protein - - - 0.00000000000000000000000000000000001574 140.0
SHD2_k127_6838259_6 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000288 53.0
SHD2_k127_6839721_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 323.0
SHD2_k127_6839721_1 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000004096 177.0
SHD2_k127_6839721_2 MacB-like periplasmic core domain K02004 - - 0.000000000004866 66.0
SHD2_k127_6840522_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005126 282.0
SHD2_k127_6840522_1 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000005717 175.0
SHD2_k127_6843794_0 Glycosyl transferases group 1 K21001 - - 0.000000000000000000000000000000000000000000001531 180.0
SHD2_k127_6843794_1 Stress responsive alpha-beta barrel - - - 0.0000000000000000000000000000000002621 137.0
SHD2_k127_6843794_2 CopG antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000000003211 112.0
SHD2_k127_6856876_0 PFAM NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 376.0
SHD2_k127_6856876_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 338.0
SHD2_k127_6856876_2 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003902 294.0
SHD2_k127_6856876_3 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009647 269.0
SHD2_k127_6856876_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000001442 197.0
SHD2_k127_6881514_0 Integral membrane sensor signal transduction histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 308.0
SHD2_k127_6881514_1 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000008312 207.0
SHD2_k127_6881514_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000002416 115.0
SHD2_k127_6891308_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002896 285.0
SHD2_k127_6891308_1 ABC transporter K06020 - 3.6.3.25 0.0000000000000000000000008212 109.0
SHD2_k127_6891308_2 ABC transporter K06020 - 3.6.3.25 0.0000000000004431 70.0
SHD2_k127_6903869_0 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 433.0
SHD2_k127_6903869_1 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 331.0
SHD2_k127_6907357_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 542.0
SHD2_k127_6907357_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000005832 108.0
SHD2_k127_6916428_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 408.0
SHD2_k127_6916428_1 Succinyl-CoA ligase like flavodoxin domain - - - 0.00000000000000000000003181 104.0
SHD2_k127_6916428_2 Universal stress protein family - - - 0.00000000000000000009498 94.0
SHD2_k127_6930357_0 (ABC) transporter K02021,K06147,K06148,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 451.0
SHD2_k127_6930357_1 PFAM glycosyl transferase family 9 K02843,K02849 - - 0.00000000000000000000000000000001396 142.0
SHD2_k127_6930357_2 Glycosyltransferase like family 2 - - - 0.0000000004907 72.0
SHD2_k127_6931906_0 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000002522 203.0
SHD2_k127_6931906_1 RNA polymerase K03088 - - 0.00000000000000000000000000000000005056 143.0
SHD2_k127_6931906_2 HlyD family secretion protein - - - 0.000000000000000000000000004875 124.0
SHD2_k127_6931906_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000001209 77.0
SHD2_k127_6966975_0 MutL protein K00854 - 2.7.1.17 1.454e-258 811.0
SHD2_k127_6966975_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 394.0
SHD2_k127_6966975_2 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 327.0
SHD2_k127_6966975_3 - - - - 0.000000000000000000000000000000000000000000000000000000006232 205.0
SHD2_k127_6966975_4 - - - - 0.00000000000000000001339 95.0
SHD2_k127_6968775_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001538 278.0
SHD2_k127_6968775_1 - - - - 0.0000000000000000000000000000000000000002289 156.0
SHD2_k127_6968775_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000008439 67.0
SHD2_k127_7002774_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 340.0
SHD2_k127_7002774_1 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 299.0
SHD2_k127_7002774_2 elongation factor Tu domain 2 protein K02355 - - 0.00000000000000000000000000000000000000000000000000000000000009873 216.0
SHD2_k127_7002774_3 Right handed beta helix region - - - 0.000000004997 71.0
SHD2_k127_7023936_0 PFAM Basic membrane lipoprotein K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 383.0
SHD2_k127_7023936_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000005175 276.0
SHD2_k127_7043077_0 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.0000000000000000000000000000000000000000000000000000000001518 209.0
SHD2_k127_7043077_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000001991 125.0
SHD2_k127_7056426_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000001309 216.0
SHD2_k127_7056426_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000003221 131.0
SHD2_k127_7056426_2 Histidine kinase K10681 - 2.7.13.3 0.000000000000000000557 100.0
SHD2_k127_7060509_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 337.0
SHD2_k127_7060509_1 PFAM Outer membrane efflux protein - - - 0.000000005624 64.0
SHD2_k127_7060509_2 AcrB/AcrD/AcrF family - - - 0.0001255 52.0
SHD2_k127_7073028_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000003081 141.0
SHD2_k127_7073028_1 Fibronectin type 3 domain - - - 0.000000000002615 77.0
SHD2_k127_7123222_0 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000001666 79.0
SHD2_k127_7123222_1 - - - - 0.000000000009969 71.0
SHD2_k127_7123222_2 Endonuclease Exonuclease Phosphatase - - - 0.0002212 53.0
SHD2_k127_7123222_3 OsmC-like protein - - - 0.0007884 49.0
SHD2_k127_7125119_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 9.347e-238 747.0
SHD2_k127_7125119_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.053e-230 722.0
SHD2_k127_7125119_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001007 263.0
SHD2_k127_7125119_3 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000003192 248.0
SHD2_k127_7125119_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000009515 118.0
SHD2_k127_7125119_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000002798 113.0
SHD2_k127_7125119_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000935 107.0
SHD2_k127_7125119_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000002912 89.0
SHD2_k127_7136877_0 Glycosyl hydrolases family 2, sugar binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 330.0
SHD2_k127_7154687_0 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005798 300.0
SHD2_k127_7154687_1 protein N-acetylglucosaminyltransferase activity K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.000005543 51.0
SHD2_k127_7185913_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002322 282.0
SHD2_k127_7185913_1 cellulose binding - - - 0.000000000000000000000000000000000000000000005114 189.0
SHD2_k127_7185913_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000009256 100.0
SHD2_k127_7185913_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.1.5.3 0.000000003869 62.0
SHD2_k127_7245643_0 SNF2 family N-terminal domain - - - 1.755e-241 762.0
SHD2_k127_7245643_1 domain protein - - - 0.000000000000000000000000000000000000000000000000002622 211.0
SHD2_k127_7245643_2 SMART Immunoglobulin C2 type - - - 0.000000000000000000000000000000000000265 164.0
SHD2_k127_7245643_3 Pkd domain containing protein - - - 0.00000000000000000000000001156 129.0
SHD2_k127_7249225_0 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 297.0
SHD2_k127_7249225_1 ROK family - - - 0.00000000000000000000000000000000000000000000000001614 185.0
SHD2_k127_7249225_2 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000009582 193.0
SHD2_k127_7251269_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 489.0
SHD2_k127_7251269_1 PFAM PTS system mannose fructose sorbose family IID component K02796 - - 0.00000000000000000000000000000005636 137.0
SHD2_k127_7251269_2 Phosphotransferase System K11189 - - 0.0000000000000000000008324 100.0
SHD2_k127_7321574_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001179 278.0
SHD2_k127_7321574_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000001068 83.0
SHD2_k127_7387330_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0004573 52.0
SHD2_k127_7399631_0 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 442.0
SHD2_k127_7401329_0 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001366 277.0
SHD2_k127_7401329_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001252 69.0
SHD2_k127_7403327_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 595.0
SHD2_k127_7403327_1 GDP-mannose 4,6 dehydratase K17947 - 5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 510.0
SHD2_k127_7403327_2 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 424.0
SHD2_k127_7403327_3 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 415.0
SHD2_k127_7403327_4 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 325.0
SHD2_k127_7403327_5 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 317.0
SHD2_k127_7403327_6 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000004544 231.0
SHD2_k127_7403327_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000005652 215.0
SHD2_k127_7403327_8 Acetyltransferase (GNAT) domain - - - 0.00003106 49.0
SHD2_k127_7403327_9 Acetyltransferase (GNAT) domain - - - 0.0001668 44.0
SHD2_k127_7404277_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 520.0
SHD2_k127_7404277_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 447.0
SHD2_k127_7404277_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 387.0
SHD2_k127_7404277_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 341.0
SHD2_k127_7404277_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000004096 282.0
SHD2_k127_7404277_5 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005082 285.0
SHD2_k127_7404277_6 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000003167 176.0
SHD2_k127_7404277_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000003673 57.0
SHD2_k127_7404277_8 Cell division protein FtsQ K03589 - - 0.00000009157 66.0
SHD2_k127_7405647_0 PFAM Sodium sulphate symporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 474.0
SHD2_k127_7409195_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 276.0
SHD2_k127_7409195_1 Rod binding protein K02395 - - 0.000000004842 66.0
SHD2_k127_7412242_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 337.0
SHD2_k127_7412242_1 belongs to the thioredoxin family K03671,K05838 - - 0.0000000000000000000000000000000000000000000000000000002845 202.0
SHD2_k127_7413049_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002953 275.0
SHD2_k127_7413049_1 radical SAM protein, TIGR01212 family K07139 - - 0.00000000000000000006019 100.0
SHD2_k127_7415885_0 Glycosyltransferase like family 2 K03606,K07011 - - 0.00000000000000000000000000000000000000000000000000000000000007652 220.0
SHD2_k127_7415885_1 BON domain - - - 0.00000000000000000001149 102.0
SHD2_k127_741602_0 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 382.0
SHD2_k127_741602_1 Domain of unknown function (DUF4150) - - - 0.000000000000000000000000000000001238 138.0
SHD2_k127_741602_2 Protein tyrosine kinase - - - 0.0000000000000000000000004931 109.0
SHD2_k127_741602_3 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000008093 115.0
SHD2_k127_741602_4 Phage late control gene D protein (GPD) K11904 - - 0.000000000000000000004804 94.0
SHD2_k127_741602_6 Pentapeptide repeats (9 copies) - - - 0.00000000002394 77.0
SHD2_k127_741602_7 PucR C-terminal helix-turn-helix domain - - - 0.0006156 49.0
SHD2_k127_7419290_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 459.0
SHD2_k127_7419290_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 414.0
SHD2_k127_7419290_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 351.0
SHD2_k127_7419760_0 CHAT domain - - - 0.000000000000000000000000000000000000000000000001624 198.0
SHD2_k127_7421965_0 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000006855 123.0
SHD2_k127_7440326_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 383.0
SHD2_k127_7440326_1 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000005067 269.0
SHD2_k127_7442779_0 PolyA polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 340.0
SHD2_k127_7442779_1 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 304.0
SHD2_k127_7442779_2 Large extracellular alpha-helical protein K06894 - - 0.0003359 49.0
SHD2_k127_7453049_0 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 408.0
SHD2_k127_7453049_1 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001045 235.0
SHD2_k127_7453049_2 CHAT domain - - - 0.000000000000000000000000000000000000000000000008158 180.0
SHD2_k127_7453049_3 Histidine triad (Hit) protein K02503 - - 0.00000000000000000000000000000000000001557 163.0
SHD2_k127_7453049_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00001519 55.0
SHD2_k127_7454882_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.000000000000000000000000000000000000000000000005552 189.0
SHD2_k127_7454882_1 - - - - 0.00000005093 59.0
SHD2_k127_7461103_0 phosphorelay sensor kinase activity - - - 0.000000000000000000000000000001418 136.0
SHD2_k127_7471776_0 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 358.0
SHD2_k127_7471776_1 Histidine kinase A domain protein - - - 0.000000000000000000000000000001794 123.0
SHD2_k127_7472182_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 441.0
SHD2_k127_7472182_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 297.0
SHD2_k127_7472182_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000003612 254.0
SHD2_k127_7472182_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000003267 94.0
SHD2_k127_7478358_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 513.0
SHD2_k127_7478358_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 344.0
SHD2_k127_7485773_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000178 280.0
SHD2_k127_7485773_1 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000002233 104.0
SHD2_k127_7485773_2 heat shock protein binding - - - 0.000004213 55.0
SHD2_k127_7488327_0 Beta-lactamase class C - - - 3.107e-216 690.0
SHD2_k127_7488327_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 326.0
SHD2_k127_7488327_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 315.0
SHD2_k127_7488327_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000007894 274.0
SHD2_k127_7488327_4 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000001569 228.0
SHD2_k127_7488327_5 Pfam:DUF2029 - - - 0.000000000000000000000000000000000000007613 160.0
SHD2_k127_7488327_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000001452 87.0
SHD2_k127_7505796_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 310.0
SHD2_k127_7505796_1 Carbamoyltransferase C-terminus K00612 - - 0.000000000001195 77.0
SHD2_k127_7506076_0 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000006281 184.0
SHD2_k127_7506076_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000001097 180.0
SHD2_k127_7506076_2 PFAM General secretory system II protein E domain protein - - - 0.0000000000000000000000000000000000000000003748 174.0
SHD2_k127_7506076_3 protein transport K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000001867 146.0
SHD2_k127_7516958_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006467 281.0
SHD2_k127_7516958_1 TPR repeat - - - 0.0000000000000000001076 98.0
SHD2_k127_7516958_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000002418 56.0
SHD2_k127_7522700_0 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 528.0
SHD2_k127_7537285_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000002143 108.0
SHD2_k127_7541702_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 568.0
SHD2_k127_7541702_1 DNA-binding response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 397.0
SHD2_k127_7541702_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000005222 207.0
SHD2_k127_7543298_0 CHASE3 domain - - - 7.537e-282 884.0
SHD2_k127_7543298_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 385.0
SHD2_k127_7543298_2 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000001051 200.0
SHD2_k127_7543298_3 HWE histidine kinase - - - 0.000000000000000000000000000006072 121.0
SHD2_k127_7545001_0 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000003794 224.0
SHD2_k127_7545001_1 bacterial-type flagellum organization K02282,K04562 - - 0.0000000000000000000000000000000000000000000000000000000005166 211.0
SHD2_k127_7545001_2 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000000000000000000000000000000000006013 208.0
SHD2_k127_7545001_3 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000006085 193.0
SHD2_k127_7557846_0 Radical SAM superfamily K06871 - - 0.00000000000000000000000000000000000000000000000000000001507 211.0
SHD2_k127_7557846_1 Peptidase, M28 - - - 0.00000001561 61.0
SHD2_k127_7574327_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 307.0
SHD2_k127_7574327_1 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000003467 251.0
SHD2_k127_7574327_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000006857 213.0
SHD2_k127_7574327_3 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000802 188.0
SHD2_k127_7577410_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 310.0
SHD2_k127_7577410_1 PFAM flagellin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 291.0
SHD2_k127_7577410_2 Flagellar protein FlaF K06602 - - 0.0000000000000000000000000005277 117.0
SHD2_k127_7577410_3 PFAM flagellar FlbT family protein K06601 - - 0.00000000000000000000000007778 111.0
SHD2_k127_7577410_4 bacterial-type flagellum-dependent cell motility K02397 - - 0.0000000000000000002625 98.0
SHD2_k127_7577410_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000003382 61.0
SHD2_k127_7577410_6 PKD domain - - - 0.0000004712 60.0
SHD2_k127_7582730_0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 498.0
SHD2_k127_7582730_1 DNA polymerase alpha chain like domain K02347 - - 0.00000000000000000000000000001885 120.0
SHD2_k127_7604231_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0000008019 62.0
SHD2_k127_761036_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 417.0
SHD2_k127_761036_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000002354 194.0
SHD2_k127_7615306_0 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000004157 184.0
SHD2_k127_7615306_1 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000000001412 130.0
SHD2_k127_7615306_2 Histidine kinase - - - 0.00000000000000000000000000003395 133.0
SHD2_k127_7615306_3 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.00000000000005451 74.0
SHD2_k127_7615306_4 - - - - 0.0004874 46.0
SHD2_k127_7625776_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 348.0
SHD2_k127_7625776_1 Permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001249 248.0
SHD2_k127_7625776_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000001212 226.0
SHD2_k127_7625776_3 SMART regulatory protein ArsR - - - 0.00000000000000000000005692 105.0
SHD2_k127_7633403_0 Immune inhibitor A peptidase M6 - - - 0.000000000000000000000000000002292 138.0
SHD2_k127_7633403_1 Fibronectin type 3 domain - - - 0.00001875 57.0
SHD2_k127_7641616_0 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 432.0
SHD2_k127_7641616_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 348.0
SHD2_k127_7649219_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 6.2e-199 628.0
SHD2_k127_7649219_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000006041 176.0
SHD2_k127_7663340_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008835 276.0
SHD2_k127_7663340_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000002581 209.0
SHD2_k127_7663340_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000001948 51.0
SHD2_k127_7666654_0 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000001217 194.0
SHD2_k127_7666654_1 PFAM glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000003417 159.0
SHD2_k127_7667230_0 metallopeptidase activity K01637 - 4.1.3.1 0.00000000000000000000000000000000004228 154.0
SHD2_k127_7668588_0 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 441.0
SHD2_k127_7668588_1 oligosaccharyl transferase activity - - - 0.000000000000000003476 94.0
SHD2_k127_7675606_0 Belongs to the glycosyl hydrolase 1 family - - - 7.766e-231 720.0
SHD2_k127_7675606_1 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.00000000000000000000000000000000000002069 147.0
SHD2_k127_7675606_2 protein conserved in bacteria - - - 0.00000000000000000000000000000144 126.0
SHD2_k127_7675606_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000001257 82.0
SHD2_k127_7680909_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.000000000000000000000000000000000000007799 160.0
SHD2_k127_76819_0 Ribosomal large subunit pseudouridine synthase A K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 487.0
SHD2_k127_76819_1 extracellular matrix structural constituent - - - 0.00000000000000003522 83.0
SHD2_k127_7682762_0 Peptidase dimerisation domain K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 368.0
SHD2_k127_7682762_1 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 355.0
SHD2_k127_7682762_2 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 303.0
SHD2_k127_7693795_0 membrane K07148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 557.0
SHD2_k127_7693795_1 PFAM peptidase M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 380.0
SHD2_k127_7693795_2 - - - - 0.0000000000000000000000000003854 119.0
SHD2_k127_7693795_3 acetyltransferase - - - 0.000000000000000000001156 96.0
SHD2_k127_7702246_0 adenosylhomocysteinase activity K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 621.0
SHD2_k127_7702246_1 Methyltransferase type 11 K03892 - - 0.0000000000000000000000000000004992 130.0
SHD2_k127_7709308_0 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 438.0
SHD2_k127_7709308_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 314.0
SHD2_k127_7728920_0 lipid kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007181 267.0
SHD2_k127_7728920_1 PAS fold - - - 0.000000000000000000000000000000000728 142.0
SHD2_k127_7728959_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002578 256.0
SHD2_k127_7728959_1 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000006419 163.0
SHD2_k127_7745741_0 long-chain fatty acid transport protein - - - 0.000837 51.0
SHD2_k127_7751824_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 8.417e-200 631.0
SHD2_k127_7751824_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 436.0
SHD2_k127_7751824_2 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000005889 247.0
SHD2_k127_7751824_3 helicase superfamily c-terminal domain - - - 0.000000000000000000000000000000000000001363 156.0
SHD2_k127_7751824_4 KaiB K08481 - - 0.000000000000000000000000000000000000004022 148.0
SHD2_k127_7751824_5 KaiB K08481 - - 0.00000000000000000000000006554 114.0
SHD2_k127_7758405_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000001807 233.0
SHD2_k127_7758405_1 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000000009153 151.0
SHD2_k127_7766707_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 373.0
SHD2_k127_7766707_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.00000003465 63.0
SHD2_k127_7766707_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000537 52.0
SHD2_k127_7769088_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1126.0
SHD2_k127_7769088_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 439.0
SHD2_k127_7773620_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1189.0
SHD2_k127_7773620_1 glutamate dehydrogenase [NAD(P)+] activity K00262 GO:0005575,GO:0005623,GO:0009986,GO:0044464 1.4.1.4 0.0000000000007961 68.0
SHD2_k127_7773620_2 metallophosphoesterase K07096 - - 0.000000000002243 70.0
SHD2_k127_7781856_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 436.0
SHD2_k127_7781856_1 - - - - 0.0000008108 58.0
SHD2_k127_7788910_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000004169 219.0
SHD2_k127_7788910_1 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000001201 196.0
SHD2_k127_7788910_2 self proteolysis - - - 0.0000000001646 71.0
SHD2_k127_7806089_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000002471 115.0
SHD2_k127_7822878_0 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000009044 126.0
SHD2_k127_7841001_0 cytochrome c - - - 0.00000000000000000000000001131 118.0
SHD2_k127_7841001_1 zinc ion transport - - - 0.000000000000000008698 93.0
SHD2_k127_7841001_2 Polysulphide reductase, NrfD K00185 - - 0.00000003535 57.0
SHD2_k127_7862935_0 PPIC-type PPIASE domain K03769,K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000003224 177.0
SHD2_k127_7862935_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000008912 164.0
SHD2_k127_7862935_2 COG0457 FOG TPR repeat - - - 0.000000006753 69.0
SHD2_k127_7862935_3 Phosphotransferase enzyme family - - - 0.000001368 60.0
SHD2_k127_7876432_0 oligoendopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 573.0
SHD2_k127_7876432_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000005836 117.0
SHD2_k127_7876432_2 Zn-dependent protease with chaperone function - - - 0.0000000005775 67.0
SHD2_k127_7890711_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 616.0
SHD2_k127_7890711_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 518.0
SHD2_k127_7890711_2 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000000000006108 187.0
SHD2_k127_7890711_3 Biotin-requiring enzyme - - - 0.00000000001541 77.0
SHD2_k127_7890711_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000003231 67.0
SHD2_k127_7891656_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001845 270.0
SHD2_k127_7891656_1 Belongs to the peptidase S8 family - - - 0.00000000000000000002863 106.0
SHD2_k127_7891656_2 - - - - 0.0000000001926 72.0
SHD2_k127_792567_0 ABC transporter C-terminal domain K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 465.0
SHD2_k127_792567_1 peptide catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000003134 227.0
SHD2_k127_792567_2 Parallel beta-helix repeats - - - 0.0000000006084 71.0
SHD2_k127_792567_3 DNA polymerase K02337 - 2.7.7.7 0.00000001625 63.0
SHD2_k127_7926382_0 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000004174 154.0
SHD2_k127_7926382_1 transduction histidine kinase - - - 0.00000000000000001483 90.0
SHD2_k127_7934645_0 regulation of microtubule-based process K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 310.0
SHD2_k127_7934645_1 Transglutaminase-like superfamily - - - 0.00000000000000004486 90.0
SHD2_k127_7935025_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 447.0
SHD2_k127_7935025_2 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 304.0
SHD2_k127_7935025_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000126 71.0
SHD2_k127_7939702_0 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 315.0
SHD2_k127_7939702_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 294.0
SHD2_k127_7939702_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001877 216.0
SHD2_k127_7939702_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000009667 195.0
SHD2_k127_7939702_4 creatininase K01470 - 3.5.2.10 0.00000000000000000000009216 104.0
SHD2_k127_803469_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 437.0
SHD2_k127_803469_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 330.0
SHD2_k127_803469_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000006663 118.0
SHD2_k127_803469_3 Ribosomal protein S21 K02970 - - 0.0000000000000003726 79.0
SHD2_k127_8076606_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 440.0
SHD2_k127_8076606_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 429.0
SHD2_k127_8076606_2 NYN domain - - - 0.0000000000000000004193 99.0
SHD2_k127_8093903_0 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000004601 93.0
SHD2_k127_8093903_1 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.0000000000001028 74.0
SHD2_k127_8127436_0 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.0000000000000001733 88.0
SHD2_k127_815004_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 423.0
SHD2_k127_815004_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000003106 173.0
SHD2_k127_81606_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 621.0
SHD2_k127_81606_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000004562 198.0
SHD2_k127_81606_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000001364 140.0
SHD2_k127_8197606_0 Flagella basal body rod protein K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 294.0
SHD2_k127_8197606_1 Flagella basal body rod protein K02392 - - 0.0000000000000000000000000000000000001642 147.0
SHD2_k127_8197606_2 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000007413 63.0
SHD2_k127_8222378_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 446.0
SHD2_k127_8222378_1 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000146 175.0
SHD2_k127_8222378_2 Peptidase family M48 - - - 0.0000004705 63.0
SHD2_k127_8223183_0 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008333 278.0
SHD2_k127_8223183_1 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000004106 186.0
SHD2_k127_8296536_0 - - - - 0.0000000000000000203 94.0
SHD2_k127_8296536_1 Protein of unknown function (DUF2723) - - - 0.00000000005066 74.0
SHD2_k127_8302771_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 8.035e-227 711.0
SHD2_k127_8328915_0 Domain of unknown function (DUF4347) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 310.0
SHD2_k127_8328915_1 LVIVD repeat K01179 - 3.2.1.4 0.00000000000006031 86.0
SHD2_k127_8328915_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000006031 71.0
SHD2_k127_8328915_3 Cna B domain protein - - - 0.0002473 54.0
SHD2_k127_8387234_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1160.0
SHD2_k127_8387234_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 5.204e-217 679.0
SHD2_k127_8387234_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 571.0
SHD2_k127_8387234_3 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002525 268.0
SHD2_k127_8387234_4 Domain of unknown function (DUF4440) - - - 0.00000000000002355 78.0
SHD2_k127_874590_0 PFAM aspartate glutamate uridylate kinase K12524 - 1.1.1.3,2.7.2.4 5.342e-199 651.0
SHD2_k127_874590_1 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 391.0
SHD2_k127_874590_2 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000192 268.0
SHD2_k127_874590_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000001425 267.0
SHD2_k127_874590_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000004619 111.0
SHD2_k127_928593_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000004523 176.0
SHD2_k127_928593_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000003203 158.0
SHD2_k127_928593_2 AntiSigma factor - - - 0.0000000000000000000001654 109.0
SHD2_k127_96596_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 415.0
SHD2_k127_96596_1 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000009398 148.0
SHD2_k127_96596_2 12 heme-binding sites - - - 0.000351 51.0
SHD2_k127_982_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 595.0
SHD2_k127_982_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 426.0
SHD2_k127_982_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 421.0