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Overview

ID MAG03380
Name SHD2_bin.3
Sample SMP0083
Taxonomy
Kingdom Bacteria
Phylum Eisenbacteria
Class RBG-16-71-46
Order CAIMUX01
Family VGJL01
Genus JAXDAY01
Species
Assembly information
Completeness (%) 94.46
Contamination (%) 5.26
GC content (%) 68.0
N50 (bp) 16,828
Genome size (bp) 3,887,569

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3082

Gene name Description KEGG GOs EC E-value Score Sequence
SHD2_k127_1036340_0 Prokaryotic cytochrome b561 - - - 0.0 1154.0
SHD2_k127_1036340_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 420.0
SHD2_k127_1067365_0 penicillin binding K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 355.0
SHD2_k127_1067365_1 Alpha-2-Macroglobulin K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 340.0
SHD2_k127_1067365_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000002028 220.0
SHD2_k127_1067365_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000001232 194.0
SHD2_k127_1067365_4 Domain of unknown function (DUF4403) - - - 0.0000000000000000000000000000000000003224 150.0
SHD2_k127_1067365_5 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000001598 114.0
SHD2_k127_1070801_0 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001557 276.0
SHD2_k127_1070801_1 Peptidase family U32 K08303 - - 0.000000000000000000000000000000000006949 143.0
SHD2_k127_1070801_2 Winged helix DNA-binding domain - - - 0.000002491 55.0
SHD2_k127_1079506_0 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000002336 202.0
SHD2_k127_1079506_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000001274 190.0
SHD2_k127_1079506_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000003112 171.0
SHD2_k127_1083081_0 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 452.0
SHD2_k127_1083081_1 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004081 277.0
SHD2_k127_1083081_10 - - - - 0.000000004168 67.0
SHD2_k127_1083081_11 RESPONSE REGULATOR receiver - - - 0.00001012 54.0
SHD2_k127_1083081_12 Catalyzes the conversion of chorismate to isochorismate K02361,K02552 - 5.4.4.2 0.0009561 48.0
SHD2_k127_1083081_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006431 279.0
SHD2_k127_1083081_3 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000000000000000000001711 249.0
SHD2_k127_1083081_4 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000001284 184.0
SHD2_k127_1083081_5 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000006281 167.0
SHD2_k127_1083081_6 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000001217 168.0
SHD2_k127_1083081_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000004954 153.0
SHD2_k127_1083081_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000005656 147.0
SHD2_k127_1083081_9 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000002114 118.0
SHD2_k127_1101127_0 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 507.0
SHD2_k127_1101127_1 PFAM Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001141 251.0
SHD2_k127_1123274_0 PFAM Aminotransferase class I and II K00639,K00652,K01906 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47,6.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 323.0
SHD2_k127_1123274_1 GtrA-like protein K00995 - 2.7.8.5 0.000000000000000000000000000000584 139.0
SHD2_k127_1123274_2 Signal transduction histidine kinase K11711 - 2.7.13.3 0.00000000000000000000000000003843 134.0
SHD2_k127_1123274_3 acyltransferase K00655 - 2.3.1.51 0.00000000000000000001215 101.0
SHD2_k127_1123274_4 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000001146 105.0
SHD2_k127_1123274_5 acetyltransferase - - - 0.00000000000000008399 93.0
SHD2_k127_1123274_6 response regulator, receiver - - - 0.00000000000002866 87.0
SHD2_k127_1123274_7 lipid kinase, YegS Rv2252 BmrU family - - - 0.000000002296 69.0
SHD2_k127_1123274_8 negative regulation of growth rate K02599 - - 0.00000179 60.0
SHD2_k127_1132408_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 475.0
SHD2_k127_1132408_1 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 346.0
SHD2_k127_1132408_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001237 277.0
SHD2_k127_1132408_3 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 0.0000000000000000000000000000000000000000000006307 180.0
SHD2_k127_1132408_4 Smr domain - - - 0.00000000000000000000001676 116.0
SHD2_k127_1132408_5 PFAM DRTGG domain - - - 0.0000000000000000000003996 103.0
SHD2_k127_1132408_6 DRTGG domain - - - 0.000000000000000002635 89.0
SHD2_k127_1132408_7 PFAM ATP-binding region - - - 0.000000000008288 73.0
SHD2_k127_1144738_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 4.989e-249 793.0
SHD2_k127_1144738_1 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 489.0
SHD2_k127_1144738_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose - - - 0.000000000000000000000000000000007964 143.0
SHD2_k127_1144738_3 PFAM DoxX K15977 - - 0.00000000000000000000000000001235 133.0
SHD2_k127_1144738_4 Leucine Rich repeats (2 copies) - - - 0.000000000000000000000000000141 130.0
SHD2_k127_1144738_5 transmembrane transport - - - 0.00000000000000001413 88.0
SHD2_k127_1144738_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000006135 92.0
SHD2_k127_1144738_7 - - - - 0.000000000000005737 79.0
SHD2_k127_1144738_9 Methionine biosynthesis protein MetW - - - 0.0000000000008325 80.0
SHD2_k127_1157797_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 1.034e-269 842.0
SHD2_k127_1157797_1 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 415.0
SHD2_k127_1157797_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000001588 166.0
SHD2_k127_1157797_3 - - - - 0.00000000000000000000000000000000000000000349 156.0
SHD2_k127_1157797_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000002688 125.0
SHD2_k127_117205_0 Polysulphide reductase K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 597.0
SHD2_k127_117205_1 Molybdopterin oxidoreductase, iron-sulfur binding subunit K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 520.0
SHD2_k127_1173749_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 393.0
SHD2_k127_1173749_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005142 257.0
SHD2_k127_1173749_2 - - - - 0.000000000000000000000000000000000000000000000007507 182.0
SHD2_k127_1173749_3 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000007243 140.0
SHD2_k127_1173749_4 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000002932 107.0
SHD2_k127_1184103_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 402.0
SHD2_k127_1184103_1 PFAM oxidoreductase domain protein K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 397.0
SHD2_k127_1184103_10 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000114 117.0
SHD2_k127_1184103_11 response regulator receiver K02490 - - 0.00000000000000004499 86.0
SHD2_k127_1184103_12 - - - - 0.0000000000003451 80.0
SHD2_k127_1184103_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 395.0
SHD2_k127_1184103_3 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 391.0
SHD2_k127_1184103_4 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003038 293.0
SHD2_k127_1184103_5 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 276.0
SHD2_k127_1184103_6 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000655 274.0
SHD2_k127_1184103_7 PAS domain K07710 - 2.7.13.3 0.000000000000000000000000000000000000000000000000006911 196.0
SHD2_k127_1184103_8 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000000000000000000002615 135.0
SHD2_k127_1184103_9 Beta-Casp domain K07576 - - 0.00000000000000000000000000000005904 136.0
SHD2_k127_1190521_0 Belongs to the peptidase S8 family - - - 1.146e-229 733.0
SHD2_k127_1190521_1 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 466.0
SHD2_k127_1190521_10 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000002958 214.0
SHD2_k127_1190521_11 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000004567 221.0
SHD2_k127_1190521_12 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000008141 181.0
SHD2_k127_1190521_13 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000000000000000000000004438 157.0
SHD2_k127_1190521_14 - - - - 0.0000000000000000000000000000000001796 139.0
SHD2_k127_1190521_15 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000003664 150.0
SHD2_k127_1190521_16 - - - - 0.0000000000000000000000000000002168 135.0
SHD2_k127_1190521_17 Fibronectin type 3 domain - - - 0.000000000000000004989 99.0
SHD2_k127_1190521_18 Domain of unknown function (DUF4395) - - - 0.000000000003373 72.0
SHD2_k127_1190521_19 cellulose binding K00505 - 1.14.18.1 0.00000000003629 72.0
SHD2_k127_1190521_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 411.0
SHD2_k127_1190521_20 Transposase - - - 0.00000001207 66.0
SHD2_k127_1190521_21 cellulase activity - - - 0.00000009576 66.0
SHD2_k127_1190521_22 - - - - 0.00004539 56.0
SHD2_k127_1190521_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 402.0
SHD2_k127_1190521_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 341.0
SHD2_k127_1190521_5 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 343.0
SHD2_k127_1190521_6 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 314.0
SHD2_k127_1190521_7 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 334.0
SHD2_k127_1190521_8 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000012 279.0
SHD2_k127_1190521_9 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000001928 223.0
SHD2_k127_1210142_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 411.0
SHD2_k127_1210142_1 MMPL family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 361.0
SHD2_k127_1210142_2 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000495 193.0
SHD2_k127_1210142_3 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000003387 128.0
SHD2_k127_1210142_4 Transglutaminase-like superfamily - - - 0.00000000000000000001759 106.0
SHD2_k127_1210142_5 Adenylate cyclase - - - 0.00001431 58.0
SHD2_k127_1232546_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 1026.0
SHD2_k127_1260826_0 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000002775 176.0
SHD2_k127_1260826_1 COG1520 FOG WD40-like repeat - - - 0.000000000000000000000000000004316 123.0
SHD2_k127_1268403_0 CarboxypepD_reg-like domain K13276 - - 0.0000000000000000003862 103.0
SHD2_k127_1268403_2 Evidence 5 No homology to any previously reported sequences K07752 - 3.4.17.22 0.00000007974 66.0
SHD2_k127_1268403_3 PFAM transglutaminase domain protein - - - 0.0007315 53.0
SHD2_k127_1280348_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 342.0
SHD2_k127_1305965_0 GTP-binding protein TypA K06207 - - 7.536e-312 964.0
SHD2_k127_1305965_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 583.0
SHD2_k127_1305965_10 Carbohydrate family 9 binding domain-like - - - 0.000000000000000001856 100.0
SHD2_k127_1305965_11 - - - - 0.000005176 57.0
SHD2_k127_1305965_2 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 381.0
SHD2_k127_1305965_3 N-terminal domain of Peptidase_S41 in eukaryotic IRBP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 338.0
SHD2_k127_1305965_4 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004458 277.0
SHD2_k127_1305965_5 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000002034 267.0
SHD2_k127_1305965_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000004557 205.0
SHD2_k127_1305965_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000002124 171.0
SHD2_k127_1305965_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000192 148.0
SHD2_k127_1305965_9 chlorophyll binding - - - 0.0000000000000000000000000003582 134.0
SHD2_k127_1332633_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 2.71e-321 997.0
SHD2_k127_1332633_1 Belongs to the peptidase M16 family K07263 - - 2.586e-308 972.0
SHD2_k127_1332633_10 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000006647 236.0
SHD2_k127_1332633_11 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000001223 218.0
SHD2_k127_1332633_12 PFAM hydroxyneurosporene synthase K09844 - 4.2.1.131 0.0000000000000000000000000000004856 138.0
SHD2_k127_1332633_13 GCN5 family acetyltransferase K22477 - 2.3.1.1 0.000000000000000000000000000865 119.0
SHD2_k127_1332633_14 Thioredoxin - - - 0.00000000000000000000006264 111.0
SHD2_k127_1332633_15 haloacid dehalogenase-like hydrolase K01243 - 3.2.2.9 0.000000000000000000001163 104.0
SHD2_k127_1332633_16 amine dehydrogenase activity - - - 0.0000000000002296 85.0
SHD2_k127_1332633_17 cell redox homeostasis K03671 - - 0.000000000002611 79.0
SHD2_k127_1332633_18 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000001438 63.0
SHD2_k127_1332633_19 Hydrogenase maturation protease K03605 - - 0.00007049 53.0
SHD2_k127_1332633_2 cellulose binding - - - 4.542e-209 679.0
SHD2_k127_1332633_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 450.0
SHD2_k127_1332633_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 359.0
SHD2_k127_1332633_5 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 363.0
SHD2_k127_1332633_6 peptidase activity, acting on L-amino acid peptides K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 337.0
SHD2_k127_1332633_7 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000001284 224.0
SHD2_k127_1332633_8 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004911 228.0
SHD2_k127_1332633_9 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000974 250.0
SHD2_k127_136135_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 3974.0
SHD2_k127_136135_1 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000005693 145.0
SHD2_k127_136135_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001599 151.0
SHD2_k127_136135_3 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000001159 125.0
SHD2_k127_136135_4 DNA-templated transcription, initiation K03088 - - 0.00000000000004372 81.0
SHD2_k127_136135_5 Evidence 5 No homology to any previously reported sequences K03088 - - 0.000004079 61.0
SHD2_k127_136135_6 IrrE N-terminal-like domain K07110 - - 0.00003945 54.0
SHD2_k127_1383766_0 Major Facilitator Superfamily K02445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 482.0
SHD2_k127_1383766_1 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 297.0
SHD2_k127_1383766_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004711 279.0
SHD2_k127_1383766_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000002908 228.0
SHD2_k127_1383766_4 ATP-dependent helicase deoxyribonuclease subunit B K16899 - 3.6.4.12 0.000000000000000000000004032 111.0
SHD2_k127_1402288_0 PFAM peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 608.0
SHD2_k127_1402288_1 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 362.0
SHD2_k127_1402288_2 ROK family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000181 285.0
SHD2_k127_1402288_3 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000001588 200.0
SHD2_k127_1402288_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000635 133.0
SHD2_k127_1402288_5 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000003536 90.0
SHD2_k127_1402288_6 Rubrerythrin - - - 0.00004571 52.0
SHD2_k127_1439577_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 331.0
SHD2_k127_1439577_1 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 298.0
SHD2_k127_1439577_2 Parallel beta-helix repeats - - - 0.0000000000000000000000001505 125.0
SHD2_k127_1457888_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 477.0
SHD2_k127_1457888_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 381.0
SHD2_k127_1457888_2 ABC transporter K02003 - - 0.000000000000000000000000000007311 121.0
SHD2_k127_1457888_3 Site-specific recombinase, DNA invertase Pin K06400 - - 0.0000000000000000006944 91.0
SHD2_k127_146752_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 396.0
SHD2_k127_146752_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 299.0
SHD2_k127_146752_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000005408 184.0
SHD2_k127_146752_3 - - - - 0.0000001022 62.0
SHD2_k127_150497_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.237e-237 753.0
SHD2_k127_150497_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 451.0
SHD2_k127_150497_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000002588 190.0
SHD2_k127_150497_11 - K01992 - - 0.00000000000000000000000000000000000000002667 175.0
SHD2_k127_150497_12 TilS substrate binding domain K04075 - 6.3.4.19 0.00000000000000000000000000000000000001415 159.0
SHD2_k127_150497_13 zinc metalloprotease K11749 - - 0.0000000000000000000000000000001347 128.0
SHD2_k127_150497_14 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000001103 121.0
SHD2_k127_150497_15 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.000000000000000001096 100.0
SHD2_k127_150497_16 Domain of unknown function (DUF4340) - - - 0.000000000006937 77.0
SHD2_k127_150497_2 TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 318.0
SHD2_k127_150497_3 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 310.0
SHD2_k127_150497_4 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 292.0
SHD2_k127_150497_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005302 282.0
SHD2_k127_150497_6 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000002519 273.0
SHD2_k127_150497_7 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000004154 243.0
SHD2_k127_150497_8 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000001309 224.0
SHD2_k127_150497_9 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000001582 211.0
SHD2_k127_1555381_0 methionyl-tRNA aminoacylation K01874,K01890,K04566,K06878 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20,6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 565.0
SHD2_k127_1555381_1 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004217 283.0
SHD2_k127_1555381_2 - - - - 0.000000000000000000000000000000000000000000001095 173.0
SHD2_k127_1555381_3 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000792 96.0
SHD2_k127_1555381_4 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000009413 91.0
SHD2_k127_1593046_0 Belongs to the RNA methyltransferase TrmD family K00554,K01770 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000002102 248.0
SHD2_k127_1593046_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001089 154.0
SHD2_k127_1593046_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000002005 128.0
SHD2_k127_1617463_0 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 524.0
SHD2_k127_1617463_1 PFAM Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000002004 174.0
SHD2_k127_1617463_2 Belongs to the peptidase S8 family K01400,K01417,K20274 - 3.4.24.28 0.000000000000000005013 101.0
SHD2_k127_1617463_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000001595 66.0
SHD2_k127_1617463_4 extracellular matrix structural constituent - - - 0.0001732 54.0
SHD2_k127_1669755_0 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 342.0
SHD2_k127_1669755_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005827 271.0
SHD2_k127_1669755_2 formate dehydrogenase K00127 - - 0.0000000000000000009503 98.0
SHD2_k127_1669755_3 - - - - 0.0000000000005972 70.0
SHD2_k127_168612_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 432.0
SHD2_k127_168612_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 361.0
SHD2_k127_183759_0 PglZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 533.0
SHD2_k127_183759_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 524.0
SHD2_k127_183759_10 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000001994 120.0
SHD2_k127_183759_11 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000224 111.0
SHD2_k127_183759_12 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K01000,K02851,K13007 - 2.7.8.13,2.7.8.33,2.7.8.35 0.000000000000000000000001994 116.0
SHD2_k127_183759_13 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.0000000000000000000003225 100.0
SHD2_k127_183759_14 Universal bacterial protein YeaZ K14742 - - 0.00000000000000000000748 105.0
SHD2_k127_183759_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 502.0
SHD2_k127_183759_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 374.0
SHD2_k127_183759_4 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 325.0
SHD2_k127_183759_5 Integral membrane sensor signal transduction histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 314.0
SHD2_k127_183759_6 RmlD substrate binding domain K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 307.0
SHD2_k127_183759_7 WxcM-like, C-terminal K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000007682 220.0
SHD2_k127_183759_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000003638 179.0
SHD2_k127_183759_9 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000007862 171.0
SHD2_k127_188099_0 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 551.0
SHD2_k127_188099_1 Phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 354.0
SHD2_k127_188099_10 metallopeptidase activity K07282,K11005 - - 0.000004515 60.0
SHD2_k127_188099_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000008597 173.0
SHD2_k127_188099_3 - - - - 0.000000000000000000000000000000000000000000006665 169.0
SHD2_k127_188099_4 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000000000003327 142.0
SHD2_k127_188099_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000006561 145.0
SHD2_k127_188099_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000001129 126.0
SHD2_k127_188099_7 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000008977 111.0
SHD2_k127_188099_8 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000003453 93.0
SHD2_k127_188327_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 611.0
SHD2_k127_188327_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004483 292.0
SHD2_k127_188327_10 PFAM Stage II sporulation E family protein - - - 0.00004439 54.0
SHD2_k127_188327_11 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0007865 52.0
SHD2_k127_188327_2 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002056 265.0
SHD2_k127_188327_3 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000000021 174.0
SHD2_k127_188327_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000003101 140.0
SHD2_k127_188327_5 domain, Protein K20276 - - 0.0000000000000000000000000000009923 135.0
SHD2_k127_188327_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000001582 137.0
SHD2_k127_188327_7 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000002703 127.0
SHD2_k127_188327_8 Cytochrome c K17223 - - 0.0000000000329 77.0
SHD2_k127_188327_9 helix_turn_helix, Lux Regulon K07684 - - 0.000000001677 68.0
SHD2_k127_1930748_0 Tricorn protease homolog - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 304.0
SHD2_k127_1930748_1 GrpB protein - - - 0.000000001932 70.0
SHD2_k127_1949220_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1136.0
SHD2_k127_1949220_1 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 2.525e-259 818.0
SHD2_k127_1949220_10 cellulose binding K12132 - 2.7.11.1 0.000002566 60.0
SHD2_k127_1949220_2 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 531.0
SHD2_k127_1949220_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 481.0
SHD2_k127_1949220_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18306 - - 0.00000000000000000000000000000000000000000007116 174.0
SHD2_k127_1949220_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000001221 119.0
SHD2_k127_1949220_6 outer membrane efflux protein - - - 0.00000000000000000000000917 116.0
SHD2_k127_1949220_7 Protein of unknown function (DUF2892) - - - 0.0000000000000000004065 87.0
SHD2_k127_1949220_8 4Fe-4S binding domain - - - 0.00000000000006797 76.0
SHD2_k127_1949220_9 domain, Protein K01113,K12373 - 3.1.3.1,3.2.1.52 0.00000002998 66.0
SHD2_k127_196242_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 325.0
SHD2_k127_196242_1 - - - - 0.00000000000000000000000000000000000000000000000000004867 197.0
SHD2_k127_196242_2 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000006477 169.0
SHD2_k127_196242_3 - - - - 0.00000000000000000000000000000000000000000007188 173.0
SHD2_k127_196242_4 - - - - 0.0000000000000000000000000000000000000000001739 170.0
SHD2_k127_2114543_0 elongation factor G K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 596.0
SHD2_k127_2114543_1 ABC transporter transmembrane K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 552.0
SHD2_k127_2114543_10 Protein of unknown function (DUF2905) - - - 0.000000000005084 78.0
SHD2_k127_2114543_11 - - - - 0.00000001819 61.0
SHD2_k127_2114543_2 ABC transporter transmembrane region K06147,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 470.0
SHD2_k127_2114543_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 408.0
SHD2_k127_2114543_4 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 298.0
SHD2_k127_2114543_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000003154 218.0
SHD2_k127_2114543_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000002262 132.0
SHD2_k127_2114543_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.0000000000000000000000000000005687 133.0
SHD2_k127_2114543_8 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000001981 117.0
SHD2_k127_2135903_0 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 370.0
SHD2_k127_2135903_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 329.0
SHD2_k127_2135903_10 - - - - 0.0000000000005699 80.0
SHD2_k127_2135903_11 - - - - 0.000000686 59.0
SHD2_k127_2135903_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002011 256.0
SHD2_k127_2135903_3 Kinase/pyrophosphorylase K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000005477 228.0
SHD2_k127_2135903_4 PFAM Bacterial transferase hexapeptide (three repeats) K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000005244 216.0
SHD2_k127_2135903_5 - - - - 0.0000000000000000000005806 113.0
SHD2_k127_2135903_6 metallopeptidase activity K01179,K01186 - 3.2.1.18,3.2.1.4 0.00000000000000000002303 102.0
SHD2_k127_2135903_7 Gram-negative-bacterium-type cell wall biogenesis - - - 0.00000000000000000006107 98.0
SHD2_k127_2135903_8 - - - - 0.00000000000000001715 83.0
SHD2_k127_2135903_9 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.000000000000004118 87.0
SHD2_k127_2141915_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 552.0
SHD2_k127_2141915_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 422.0
SHD2_k127_2141915_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 321.0
SHD2_k127_2141915_3 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.00000000000000000000000000000000000000000001733 164.0
SHD2_k127_2141915_4 PFAM Protein-tyrosine phosphatase, low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.0000000000000000000000002575 111.0
SHD2_k127_2141915_5 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000154 109.0
SHD2_k127_2163354_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 490.0
SHD2_k127_2163354_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 359.0
SHD2_k127_2163354_10 - - - - 0.0007624 51.0
SHD2_k127_2163354_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 294.0
SHD2_k127_2163354_3 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009441 269.0
SHD2_k127_2163354_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004386 254.0
SHD2_k127_2163354_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000001117 216.0
SHD2_k127_2163354_6 membrane - - - 0.0000000000000000000000000000000000000000000000000003392 194.0
SHD2_k127_2163354_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000001383 179.0
SHD2_k127_2163354_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.000000000000000001895 99.0
SHD2_k127_2163354_9 - - - - 0.000000000000000003418 101.0
SHD2_k127_2164842_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 4.087e-205 660.0
SHD2_k127_2164842_1 (ABC) transporter K06147,K06148,K11085,K16787,K18104,K18889 - 3.6.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 398.0
SHD2_k127_2164842_10 translation initiation factor activity K06996 - - 0.000000000000000001257 90.0
SHD2_k127_2164842_11 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000001075 75.0
SHD2_k127_2164842_12 gas vesicle protein - - - 0.0000001562 57.0
SHD2_k127_2164842_13 ATP-independent chaperone mediated protein folding K02005 - - 0.00006128 52.0
SHD2_k127_2164842_14 LysM domain - - - 0.000117 55.0
SHD2_k127_2164842_2 ABC transporter transmembrane region K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 365.0
SHD2_k127_2164842_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 346.0
SHD2_k127_2164842_5 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000003973 227.0
SHD2_k127_2164842_6 - - - - 0.000000000000000000000000000000000000000000000000001235 211.0
SHD2_k127_2164842_7 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000006939 141.0
SHD2_k127_2164842_8 cellulose binding - - - 0.00000000000000000000000000000263 138.0
SHD2_k127_2164842_9 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000007217 108.0
SHD2_k127_2169209_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 451.0
SHD2_k127_2169209_1 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 323.0
SHD2_k127_2169209_10 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000002248 124.0
SHD2_k127_2169209_11 Oxygen tolerance - - - 0.00000000000000004527 96.0
SHD2_k127_2169209_12 tetratricopeptide repeat - - - 0.0000000000000004109 91.0
SHD2_k127_2169209_13 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000005867 80.0
SHD2_k127_2169209_14 - - - - 0.0000000000004437 81.0
SHD2_k127_2169209_15 LVIVD repeat K01179 - 3.2.1.4 0.0000000000007916 82.0
SHD2_k127_2169209_16 Tetratricopeptide repeat protein - - - 0.000000000001048 82.0
SHD2_k127_2169209_17 - - - - 0.00000000001226 77.0
SHD2_k127_2169209_18 Belongs to the 5'-nucleotidase family K01081,K07004,K11751 - 3.1.3.5,3.6.1.45 0.000000002473 70.0
SHD2_k127_2169209_19 C4-type zinc ribbon domain K07164 - - 0.0000003469 58.0
SHD2_k127_2169209_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 323.0
SHD2_k127_2169209_20 WD40 repeats - - - 0.0000552 56.0
SHD2_k127_2169209_3 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009431 290.0
SHD2_k127_2169209_4 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003071 261.0
SHD2_k127_2169209_5 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000005711 231.0
SHD2_k127_2169209_6 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000503 200.0
SHD2_k127_2169209_7 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000001986 190.0
SHD2_k127_2169209_8 Rhomboid family - - - 0.0000000000000000000000000000000000000000000003095 175.0
SHD2_k127_2169209_9 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000004037 145.0
SHD2_k127_2184314_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 9.267e-217 685.0
SHD2_k127_2184314_1 RNase H K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000002326 184.0
SHD2_k127_2184314_10 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000003328 83.0
SHD2_k127_2184314_12 PFAM filamentation induced by cAMP protein Fic - - - 0.00003261 55.0
SHD2_k127_2184314_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000009344 156.0
SHD2_k127_2184314_3 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000003216 139.0
SHD2_k127_2184314_4 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000001599 142.0
SHD2_k127_2184314_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000001365 129.0
SHD2_k127_2184314_6 transcription factor binding - - - 0.000000000000000000000000000002297 124.0
SHD2_k127_2184314_7 DoxX family K15977 - - 0.00000000000000000001838 105.0
SHD2_k127_2184314_8 cheY-homologous receiver domain - - - 0.00000000000000000007515 91.0
SHD2_k127_2184314_9 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000005527 87.0
SHD2_k127_2185503_0 Belongs to the ClpA ClpB family K03696 - - 3.708e-293 915.0
SHD2_k127_2185503_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 541.0
SHD2_k127_2185503_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000005856 175.0
SHD2_k127_2185503_11 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000009971 165.0
SHD2_k127_2185503_12 protein with conserved CXXC pairs K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000000000000004282 121.0
SHD2_k127_2185503_13 Trypsin-like serine protease K01337 - 3.4.21.50 0.000000000000000000006756 110.0
SHD2_k127_2185503_14 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000001903 97.0
SHD2_k127_2185503_15 Bacterial Ig-like domain (group 1) - - - 0.00000001332 70.0
SHD2_k127_2185503_16 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000002815 55.0
SHD2_k127_2185503_17 Bacterial Ig-like domain (group 1) - - - 0.00000005262 68.0
SHD2_k127_2185503_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 505.0
SHD2_k127_2185503_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 450.0
SHD2_k127_2185503_4 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009692 347.0
SHD2_k127_2185503_5 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 306.0
SHD2_k127_2185503_6 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000505 279.0
SHD2_k127_2185503_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002019 275.0
SHD2_k127_2185503_8 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000001883 239.0
SHD2_k127_2185503_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000006742 201.0
SHD2_k127_2205302_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 512.0
SHD2_k127_2205302_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 395.0
SHD2_k127_2205302_2 bacterial-type flagellum-dependent cell motility K01119,K06113,K12685,K20276 - 3.1.3.6,3.1.4.16,3.2.1.99 0.0000001823 65.0
SHD2_k127_2213150_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 453.0
SHD2_k127_2213150_1 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000001583 225.0
SHD2_k127_2213150_2 transferase activity, transferring glycosyl groups K01179,K01356,K13735,K21449 - 3.2.1.4,3.4.21.88 0.0000000000000000000000000000003408 136.0
SHD2_k127_2213150_3 cellulose binding - - - 0.000000006397 65.0
SHD2_k127_22241_0 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 486.0
SHD2_k127_22241_1 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 337.0
SHD2_k127_22241_10 Tellurite resistance protein TehB - - - 0.0000000000000001507 91.0
SHD2_k127_22241_11 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.00000001717 66.0
SHD2_k127_22241_12 AAA domain - - - 0.00000007183 65.0
SHD2_k127_22241_13 extracellular matrix structural constituent - - - 0.0000004059 63.0
SHD2_k127_22241_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0004008 52.0
SHD2_k127_22241_2 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003625 279.0
SHD2_k127_22241_3 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000001253 224.0
SHD2_k127_22241_4 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000002078 224.0
SHD2_k127_22241_5 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000006561 195.0
SHD2_k127_22241_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.00000000000000000000000000000000000002152 149.0
SHD2_k127_22241_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.000000000000000000000000000000006137 144.0
SHD2_k127_22241_8 phosphorelay signal transduction system - - - 0.0000000000000000000000000004451 120.0
SHD2_k127_22241_9 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L - - - 0.00000000000000000000000002038 117.0
SHD2_k127_2238372_0 OPT oligopeptide transporter protein - - - 6.457e-200 644.0
SHD2_k127_2238372_1 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 398.0
SHD2_k127_2238372_10 Molybdate ABC transporter K02018 - - 0.0000000000000000000000000000000000000000000000006222 186.0
SHD2_k127_2238372_11 ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - 0.000000000000000000000000000006105 129.0
SHD2_k127_2238372_12 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000009703 103.0
SHD2_k127_2238372_13 - - - - 0.00000001128 66.0
SHD2_k127_2238372_14 Bacterial pre-peptidase C-terminal domain - - - 0.0004168 52.0
SHD2_k127_2238372_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 304.0
SHD2_k127_2238372_3 ABC-type polar amino acid transport system ATPase component K09972 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007036 293.0
SHD2_k127_2238372_4 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000005787 247.0
SHD2_k127_2238372_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000001515 194.0
SHD2_k127_2238372_6 PFAM binding-protein-dependent transport systems inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000002118 192.0
SHD2_k127_2238372_7 transcriptional regulator K13572 - - 0.0000000000000000000000000000000000000000000000000002888 199.0
SHD2_k127_2238372_8 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000006387 190.0
SHD2_k127_2238372_9 amino acid transport K02029,K02030 - - 0.00000000000000000000000000000000000000000000000002372 195.0
SHD2_k127_2246351_0 Multicopper oxidase K22349 - 1.16.3.3 9.758e-235 737.0
SHD2_k127_2250679_0 ABC transporter K02021,K06147,K06148,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000136 237.0
SHD2_k127_2250679_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000007715 127.0
SHD2_k127_2250679_2 O-Antigen ligase K18814 - - 0.0000000003042 71.0
SHD2_k127_2261870_0 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 5.765e-213 691.0
SHD2_k127_2261870_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 568.0
SHD2_k127_2261870_10 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009274 268.0
SHD2_k127_2261870_11 cellulase activity K06882 - - 0.00000000000000000000000000000000000000000000000000000007573 207.0
SHD2_k127_2261870_12 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000008355 192.0
SHD2_k127_2261870_13 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000002068 198.0
SHD2_k127_2261870_14 peptidase activity, acting on L-amino acid peptides K07752 - 3.4.17.22 0.0000000000000000000000000000000000000000000001459 188.0
SHD2_k127_2261870_15 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000003296 162.0
SHD2_k127_2261870_16 PFAM peptidase - - - 0.000000000000000000000000000000000000001185 160.0
SHD2_k127_2261870_17 ECF sigma factor K03088 - - 0.0000000000000000000000000000000005555 138.0
SHD2_k127_2261870_18 Secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000000001629 129.0
SHD2_k127_2261870_19 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000002997 145.0
SHD2_k127_2261870_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 561.0
SHD2_k127_2261870_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000459 116.0
SHD2_k127_2261870_21 carbon dioxide binding K04653 - - 0.0000000000000000000000003725 107.0
SHD2_k127_2261870_22 long-chain fatty acid transport protein - - - 0.000000000000000000000007529 113.0
SHD2_k127_2261870_23 Polymer-forming cytoskeletal - - - 0.00000000002456 75.0
SHD2_k127_2261870_24 - - - - 0.000000001687 67.0
SHD2_k127_2261870_25 cellulose binding - - - 0.0000002778 64.0
SHD2_k127_2261870_26 FlgD Ig-like domain - - - 0.000000555 61.0
SHD2_k127_2261870_29 Putative zinc-finger - - - 0.00001292 57.0
SHD2_k127_2261870_3 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 455.0
SHD2_k127_2261870_30 AntiSigma factor K03088 - - 0.0000607 53.0
SHD2_k127_2261870_4 PFAM Transketolase central region K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 335.0
SHD2_k127_2261870_5 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001603 296.0
SHD2_k127_2261870_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001273 287.0
SHD2_k127_2261870_7 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002659 291.0
SHD2_k127_2261870_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000007744 276.0
SHD2_k127_2261870_9 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005308 280.0
SHD2_k127_2264040_0 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 353.0
SHD2_k127_2264040_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 342.0
SHD2_k127_2264040_2 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000002859 186.0
SHD2_k127_2265672_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 1564.0
SHD2_k127_2265672_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 404.0
SHD2_k127_2271937_0 positive regulation of proteasomal protein catabolic process - - - 0.0000000000000000000000001202 125.0
SHD2_k127_2273402_0 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000001631 169.0
SHD2_k127_2276841_0 PFAM ABC transporter related K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 333.0
SHD2_k127_2276841_1 ABC-2 family transporter protein K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003493 267.0
SHD2_k127_2276841_2 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000001378 185.0
SHD2_k127_2276841_3 SMART Tetratricopeptide domain protein - - - 0.000001314 61.0
SHD2_k127_2308630_0 soluble inorganic K01507 GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0008150,GO:0010035,GO:0010038,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0050896 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006023 248.0
SHD2_k127_2308630_1 COG3794 Plastocyanin - - - 0.0001963 53.0
SHD2_k127_2320343_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 430.0
SHD2_k127_2320343_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 415.0
SHD2_k127_2320343_10 adenylate kinase activity - - - 0.000000000000000000000000000000000008651 144.0
SHD2_k127_2320343_11 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000001434 139.0
SHD2_k127_2320343_12 Protein of unknown function (DUF3788) - - - 0.000000000000000000000000000000001233 134.0
SHD2_k127_2320343_13 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000003211 126.0
SHD2_k127_2320343_14 transcription activator, effector binding - - - 0.00000000000000000000000009513 113.0
SHD2_k127_2320343_16 - - - - 0.00000002088 65.0
SHD2_k127_2320343_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001262 274.0
SHD2_k127_2320343_3 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003787 262.0
SHD2_k127_2320343_4 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004541 240.0
SHD2_k127_2320343_5 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000336 193.0
SHD2_k127_2320343_6 Uncharacterised protein family UPF0066 K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000001173 184.0
SHD2_k127_2320343_7 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000001817 181.0
SHD2_k127_2320343_9 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000905 164.0
SHD2_k127_2336155_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 422.0
SHD2_k127_2336155_1 mRNA catabolic process K06950,K09163 - - 0.00000000000000000000000000000000000000000000000000000000000007644 222.0
SHD2_k127_2336155_2 Parallel beta-helix repeats - - - 0.000000000000000000000000007649 121.0
SHD2_k127_2336155_3 amine dehydrogenase activity K21449 - - 0.0000000000000000000000008077 121.0
SHD2_k127_2336155_4 - - - - 0.0001277 49.0
SHD2_k127_233686_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 395.0
SHD2_k127_233686_1 PFAM ABC transporter K02003,K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000009005 227.0
SHD2_k127_233686_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000001676 218.0
SHD2_k127_233686_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000002882 169.0
SHD2_k127_233686_4 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.000000000000000000000003747 113.0
SHD2_k127_233686_5 - - - - 0.0000000000000000000005335 99.0
SHD2_k127_233686_6 integral membrane protein K00728 - 2.4.1.109 0.00000000000002382 86.0
SHD2_k127_2347039_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1233.0
SHD2_k127_2347039_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 3.512e-275 866.0
SHD2_k127_2347039_10 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000001816 241.0
SHD2_k127_2347039_11 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000002629 226.0
SHD2_k127_2347039_12 Hep Hag repeat protein - - - 0.000000000000000000000000000000000000000000000000000005416 210.0
SHD2_k127_2347039_13 Glyoxalase bleomycin resistance protein dioxygenase superfamily protein 19 - - - 0.00000000000000000000000000000000000000000000000001323 184.0
SHD2_k127_2347039_14 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000003032 179.0
SHD2_k127_2347039_15 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000013 158.0
SHD2_k127_2347039_16 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000003458 144.0
SHD2_k127_2347039_17 membrane transporter protein K07090 - - 0.000000000000000000000000000001341 126.0
SHD2_k127_2347039_18 Domain of unknown function (DUF4389) - - - 0.00000000000000009356 86.0
SHD2_k127_2347039_19 cellulose binding K00505 - 1.14.18.1 0.000000002539 65.0
SHD2_k127_2347039_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 585.0
SHD2_k127_2347039_20 DNA-templated transcription, initiation K03088 - - 0.000001046 53.0
SHD2_k127_2347039_21 - - - - 0.000002783 56.0
SHD2_k127_2347039_3 Peptidase S9, prolyl oligopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 457.0
SHD2_k127_2347039_4 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 448.0
SHD2_k127_2347039_5 Zinc metalloprotease (Elastase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 410.0
SHD2_k127_2347039_6 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 355.0
SHD2_k127_2347039_7 TIGR00266 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003287 269.0
SHD2_k127_2347039_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002777 265.0
SHD2_k127_2347039_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004747 250.0
SHD2_k127_2371610_0 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 1.884e-207 673.0
SHD2_k127_2371610_1 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 429.0
SHD2_k127_2371610_10 Membrane - - - 0.0000001592 61.0
SHD2_k127_2371610_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 311.0
SHD2_k127_2371610_3 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000003118 195.0
SHD2_k127_2371610_4 RNase_H superfamily K07502 - - 0.00000000000000000000000000000009769 133.0
SHD2_k127_2371610_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000001617 127.0
SHD2_k127_2371610_7 PFAM acylphosphatase K01512 - 3.6.1.7 0.0000000000000001154 94.0
SHD2_k127_2371610_8 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000001019 57.0
SHD2_k127_2371610_9 glutamine amidotransferase K07008 - 3.5.1.118 0.00000007206 65.0
SHD2_k127_2377226_0 ABC transporter K02021,K06147,K06148,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 437.0
SHD2_k127_2377226_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 336.0
SHD2_k127_2377226_2 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.000000000000000000001062 105.0
SHD2_k127_2384945_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 287.0
SHD2_k127_2388818_0 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000001502 218.0
SHD2_k127_2388818_1 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000001606 219.0
SHD2_k127_2388818_2 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000004908 184.0
SHD2_k127_2388818_3 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000001771 180.0
SHD2_k127_2388818_4 nucleotidyltransferase activity - - - 0.00000000000000000000000007542 116.0
SHD2_k127_2388818_5 - - - - 0.000000000007065 74.0
SHD2_k127_2388818_6 COG0457 FOG TPR repeat - - - 0.0002828 52.0
SHD2_k127_2389461_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 2.429e-195 617.0
SHD2_k127_2389461_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 540.0
SHD2_k127_2389461_10 Glycosyl transferase family 41 - - - 0.00002887 57.0
SHD2_k127_2389461_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 414.0
SHD2_k127_2389461_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 319.0
SHD2_k127_2389461_4 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002784 299.0
SHD2_k127_2389461_5 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008738 266.0
SHD2_k127_2389461_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000003007 231.0
SHD2_k127_2389461_7 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000002137 191.0
SHD2_k127_2389461_8 Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro K07025 - - 0.0000000000000000000000000001732 124.0
SHD2_k127_2389461_9 - - - - 0.0000000000000000000000001047 107.0
SHD2_k127_2404445_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 3.859e-210 671.0
SHD2_k127_2404445_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 344.0
SHD2_k127_2404445_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000006013 193.0
SHD2_k127_2404445_3 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000003154 174.0
SHD2_k127_2404445_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000002584 130.0
SHD2_k127_2404445_5 Domain of unknown function (DUF4870) - - - 0.0000000003501 66.0
SHD2_k127_2404445_6 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02342,K03763 - 2.7.7.7 0.0004207 45.0
SHD2_k127_2426135_0 DNA-binding response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 529.0
SHD2_k127_2426135_1 HAMP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 430.0
SHD2_k127_2426135_2 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 306.0
SHD2_k127_2426135_3 cheY-homologous receiver domain - - - 0.0000000000000000000000005248 114.0
SHD2_k127_2441986_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 4.408e-312 979.0
SHD2_k127_2441986_1 ATPase domain of DNA mismatch repair MUTS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 572.0
SHD2_k127_2441986_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000002214 206.0
SHD2_k127_2441986_11 peptide-methionine (R)-S-oxide reductase activity K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000002994 197.0
SHD2_k127_2441986_12 - - - - 0.000000000000000000000000000000000000000000000146 177.0
SHD2_k127_2441986_13 STAS-like domain of unknown function (DUF4325) - - - 0.000000000000000000000000000000000000000000002049 179.0
SHD2_k127_2441986_14 histidine kinase A domain protein - - - 0.0000000000000000000000005615 123.0
SHD2_k127_2441986_15 methionine synthase K00548 - 2.1.1.13 0.00000000000000588 86.0
SHD2_k127_2441986_16 PFAM Outer membrane efflux protein - - - 0.000000000000007355 88.0
SHD2_k127_2441986_17 Diguanylate cyclase - - - 0.00000000001931 78.0
SHD2_k127_2441986_18 Cell Wall K01448 - 3.5.1.28 0.000002324 59.0
SHD2_k127_2441986_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 398.0
SHD2_k127_2441986_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 374.0
SHD2_k127_2441986_4 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 371.0
SHD2_k127_2441986_5 GNAT acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003624 269.0
SHD2_k127_2441986_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003204 251.0
SHD2_k127_2441986_7 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000002569 237.0
SHD2_k127_2441986_8 cobalamin binding K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000001568 223.0
SHD2_k127_2441986_9 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000002702 218.0
SHD2_k127_245587_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.301e-292 922.0
SHD2_k127_245587_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001156 274.0
SHD2_k127_245587_2 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000108 200.0
SHD2_k127_245587_3 - - - - 0.0000000000000000000000000000000000000000000000006152 183.0
SHD2_k127_245587_4 - - - - 0.000000000000000000000000000000000000001615 151.0
SHD2_k127_245587_5 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0002703 51.0
SHD2_k127_2461775_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 516.0
SHD2_k127_2461775_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family K13687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 404.0
SHD2_k127_2461775_2 Carotene biosynthesis associated membrane protein K14337,K14339 GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000003636 63.0
SHD2_k127_2461775_3 - - - - 0.000004026 59.0
SHD2_k127_2461775_4 domain, Protein - - - 0.000007026 59.0
SHD2_k127_2461775_5 cellulose binding - - - 0.0002 53.0
SHD2_k127_2475608_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 434.0
SHD2_k127_2475608_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000005438 130.0
SHD2_k127_2496362_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000002421 233.0
SHD2_k127_2496362_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000002764 237.0
SHD2_k127_2496362_2 transposition, DNA-mediated K02342 - 2.7.7.7 0.00000000000000000000000000000000000004908 157.0
SHD2_k127_2496362_3 Sigma-70, region 4 K03088 - - 0.00000007353 64.0
SHD2_k127_2497217_0 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 587.0
SHD2_k127_2497217_2 Belongs to the metal hydrolase YfiT family - - - 0.00000000000000000000000000000000000000000000000000000000000000005607 228.0
SHD2_k127_2500801_0 threonyl-tRNA aminoacylation K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 7.918e-209 669.0
SHD2_k127_2500801_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 489.0
SHD2_k127_2500801_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000003649 228.0
SHD2_k127_2500801_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000001686 110.0
SHD2_k127_2500801_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000003824 113.0
SHD2_k127_2500801_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000001805 98.0
SHD2_k127_2500801_6 - - - - 0.000000000004641 72.0
SHD2_k127_2504047_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 345.0
SHD2_k127_2504047_1 diguanylate cyclase - - - 0.000000000000000000000000169 121.0
SHD2_k127_2504047_2 TIGRFAM sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family K13006,K19429 - - 0.000000000000000000009296 95.0
SHD2_k127_2504047_3 Multicopper oxidase - - - 0.00001963 56.0
SHD2_k127_2504047_4 Protein of unknown function (DUF1003) - - - 0.0005261 46.0
SHD2_k127_2508490_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 432.0
SHD2_k127_2508490_1 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000009607 99.0
SHD2_k127_2550432_0 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 345.0
SHD2_k127_2550432_1 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000003224 119.0
SHD2_k127_2573931_0 CHAD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000257 282.0
SHD2_k127_2573931_1 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000000000000000000000000000000003424 212.0
SHD2_k127_2621667_0 mannose metabolic process K01191 - 3.2.1.24 2.115e-301 968.0
SHD2_k127_2621667_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 507.0
SHD2_k127_2621667_2 ABC transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 486.0
SHD2_k127_2621667_3 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 440.0
SHD2_k127_2621667_4 PFAM periplasmic binding protein LacI transcriptional regulator K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001659 276.0
SHD2_k127_2621667_5 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002312 244.0
SHD2_k127_2621667_6 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.0000000000000000000000824 116.0
SHD2_k127_2627393_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 434.0
SHD2_k127_2627393_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 315.0
SHD2_k127_2627393_10 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000001039 182.0
SHD2_k127_2627393_11 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000218 143.0
SHD2_k127_2627393_12 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000005678 124.0
SHD2_k127_2627393_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000005831 117.0
SHD2_k127_2627393_14 AAA domain K16554 - - 0.00000000000000001815 95.0
SHD2_k127_2627393_15 Chain length determinant protein - - - 0.0000000009094 71.0
SHD2_k127_2627393_16 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0004271 50.0
SHD2_k127_2627393_2 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 317.0
SHD2_k127_2627393_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003261 268.0
SHD2_k127_2627393_4 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000001916 255.0
SHD2_k127_2627393_5 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001725 249.0
SHD2_k127_2627393_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000005869 238.0
SHD2_k127_2627393_7 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000002729 227.0
SHD2_k127_2627393_8 Sugar nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000009126 226.0
SHD2_k127_2627393_9 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000001238 221.0
SHD2_k127_2653966_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 553.0
SHD2_k127_2653966_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 386.0
SHD2_k127_2653966_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000004859 186.0
SHD2_k127_2653966_11 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000624 188.0
SHD2_k127_2653966_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000001669 171.0
SHD2_k127_2653966_13 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000001888 172.0
SHD2_k127_2653966_14 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000004636 149.0
SHD2_k127_2653966_15 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000002313 142.0
SHD2_k127_2653966_16 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000002154 142.0
SHD2_k127_2653966_17 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000007014 115.0
SHD2_k127_2653966_18 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000001678 113.0
SHD2_k127_2653966_19 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000007467 102.0
SHD2_k127_2653966_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 303.0
SHD2_k127_2653966_20 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000008549 106.0
SHD2_k127_2653966_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000008817 84.0
SHD2_k127_2653966_22 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001308 76.0
SHD2_k127_2653966_23 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000004629 68.0
SHD2_k127_2653966_24 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000005319 68.0
SHD2_k127_2653966_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005588 274.0
SHD2_k127_2653966_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000001279 239.0
SHD2_k127_2653966_5 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000002771 238.0
SHD2_k127_2653966_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000192 238.0
SHD2_k127_2653966_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000005422 213.0
SHD2_k127_2653966_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000002353 212.0
SHD2_k127_2653966_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001063 188.0
SHD2_k127_2669513_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 574.0
SHD2_k127_2669513_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 309.0
SHD2_k127_2669513_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595,K06883 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004755 282.0
SHD2_k127_2669513_3 PFAM EamA-like transporter family - - - 0.000000000000000000000000000000001864 142.0
SHD2_k127_2669513_4 Biliverdin reductase A K00214 GO:0000166,GO:0003674,GO:0003824,GO:0004074,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0019439,GO:0033013,GO:0033015,GO:0034641,GO:0036094,GO:0042167,GO:0042168,GO:0042440,GO:0044237,GO:0044248,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.3.1.24 0.000000000000000000000007862 111.0
SHD2_k127_2673584_0 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000006788 153.0
SHD2_k127_2673584_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000008982 150.0
SHD2_k127_2675804_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 492.0
SHD2_k127_2675804_1 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 441.0
SHD2_k127_2675804_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000415 135.0
SHD2_k127_2675804_11 Belongs to the UPF0102 family K07460 - - 0.00000000000000002874 87.0
SHD2_k127_2675804_12 coenzyme A transferase K01028 - 2.8.3.5 0.000000000003478 74.0
SHD2_k127_2675804_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 406.0
SHD2_k127_2675804_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 389.0
SHD2_k127_2675804_4 Coenzyme A transferase K01027,K01028,K01034 - 2.8.3.5,2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 346.0
SHD2_k127_2675804_5 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000181 283.0
SHD2_k127_2675804_6 PFAM Glycosyl transferases group 1 K16703 - - 0.0000000000000000000000000000000000000000000000000000000000616 210.0
SHD2_k127_2675804_7 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000001892 201.0
SHD2_k127_2675804_8 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000001045 195.0
SHD2_k127_2675804_9 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000001774 141.0
SHD2_k127_2708709_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1349.0
SHD2_k127_2708709_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1170.0
SHD2_k127_2708709_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 289.0
SHD2_k127_2708709_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000001085 221.0
SHD2_k127_2708709_4 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000006501 196.0
SHD2_k127_2708709_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000001314 144.0
SHD2_k127_2708709_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000005572 138.0
SHD2_k127_2708709_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001308 76.0
SHD2_k127_2708709_8 Ribosomal protein L33 K02913 - - 0.00000000000000209 78.0
SHD2_k127_2708709_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000007764 55.0
SHD2_k127_2724535_0 PFAM Diacylglycerol kinase, catalytic - - - 0.000000000000000000000000005509 121.0
SHD2_k127_2724535_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000002081 87.0
SHD2_k127_2725514_0 M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 454.0
SHD2_k127_2725514_1 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000008452 181.0
SHD2_k127_2725514_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000002891 173.0
SHD2_k127_2725514_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000003038 177.0
SHD2_k127_2725514_4 Predicted membrane protein (DUF2079) - - - 0.00000000000000000000000000000000000000004971 172.0
SHD2_k127_2725514_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000001476 92.0
SHD2_k127_2725514_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000007156 62.0
SHD2_k127_2774594_0 Belongs to the Orn Lys Arg decarboxylase class-II family K00928,K12526 - 2.7.2.4,4.1.1.20 5.559e-316 990.0
SHD2_k127_2774594_1 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 441.0
SHD2_k127_2774594_2 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 391.0
SHD2_k127_2774594_3 ATPase BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 350.0
SHD2_k127_2774594_4 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000002724 257.0
SHD2_k127_2774594_5 Leucine-rich repeat K13730 - - 0.000000000000000000000003995 116.0
SHD2_k127_2774594_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000002543 63.0
SHD2_k127_2776462_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 552.0
SHD2_k127_2776462_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 354.0
SHD2_k127_2776462_10 Redoxin - - - 0.0000000000000000000000000000000000009834 144.0
SHD2_k127_2776462_11 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000003388 152.0
SHD2_k127_2776462_12 Domain of unknown function (DUF4266) - - - 0.000000000000004839 84.0
SHD2_k127_2776462_13 Tetratricopeptide repeat - - - 0.00000000002473 69.0
SHD2_k127_2776462_2 ApbE family K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 321.0
SHD2_k127_2776462_3 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000001152 243.0
SHD2_k127_2776462_4 Phosphoesterase family K21302 GO:0003674,GO:0003824,GO:0003993,GO:0004438,GO:0004805,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006139,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006742,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009109,GO:0009117,GO:0009166,GO:0009987,GO:0016310,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019203,GO:0019362,GO:0019364,GO:0019438,GO:0019439,GO:0019637,GO:0030258,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046486,GO:0046488,GO:0046496,GO:0046700,GO:0046834,GO:0046854,GO:0050189,GO:0050192,GO:0051186,GO:0051187,GO:0052744,GO:0052866,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072526,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.3.64 0.00000000000000000000000000000000000000000000000000000000000006524 228.0
SHD2_k127_2776462_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000004541 228.0
SHD2_k127_2776462_6 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000004813 188.0
SHD2_k127_2776462_7 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000000000000000002564 164.0
SHD2_k127_2776462_8 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000003402 170.0
SHD2_k127_2776462_9 peptidyl-tyrosine sulfation K13992 - - 0.00000000000000000000000000000000000002178 156.0
SHD2_k127_2782866_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 626.0
SHD2_k127_2782866_1 transmembrane transporter activity K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 599.0
SHD2_k127_2782866_10 PFAM response regulator receiver K07667 - - 0.00000000000000000000000000000000000000000000000000000002986 206.0
SHD2_k127_2782866_11 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000008128 191.0
SHD2_k127_2782866_12 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.00000000000000000000000000000000001375 154.0
SHD2_k127_2782866_13 Response regulator, receiver - - - 0.00000000000000000000009878 102.0
SHD2_k127_2782866_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000001507 61.0
SHD2_k127_2782866_15 PFAM outer membrane efflux protein K15725 - - 0.000302 48.0
SHD2_k127_2782866_2 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 546.0
SHD2_k127_2782866_3 plastoquinone (Complex I) K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 503.0
SHD2_k127_2782866_4 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 424.0
SHD2_k127_2782866_5 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 376.0
SHD2_k127_2782866_6 NADH ubiquinone oxidoreductase, 20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 335.0
SHD2_k127_2782866_7 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 306.0
SHD2_k127_2782866_8 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002709 274.0
SHD2_k127_2782866_9 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000003759 218.0
SHD2_k127_2784256_0 Tricorn protease homolog K08676 - - 0.0 1217.0
SHD2_k127_2784256_1 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 5.285e-237 750.0
SHD2_k127_2784256_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000005402 152.0
SHD2_k127_2784256_11 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000009861 145.0
SHD2_k127_2784256_12 - - - - 0.0000000000000000000003604 103.0
SHD2_k127_2784256_13 Protein of unknown function, DUF255 - - - 0.00000000002011 75.0
SHD2_k127_2784256_14 - - - - 0.00001303 50.0
SHD2_k127_2784256_15 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00008383 51.0
SHD2_k127_2784256_2 ABC transporter transmembrane region K06147 - - 1.716e-209 667.0
SHD2_k127_2784256_3 Protein of unknown function, DUF255 K06888 - - 4.394e-206 662.0
SHD2_k127_2784256_4 ABC transporter transmembrane region K06147 - - 8.816e-194 622.0
SHD2_k127_2784256_5 YidE YbjL duplication domain protein K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 416.0
SHD2_k127_2784256_6 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 380.0
SHD2_k127_2784256_7 MmgE/PrpD family K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 344.0
SHD2_k127_2784256_8 DinB family - - - 0.0000000000000000000000000000000000000000000000001171 184.0
SHD2_k127_2784256_9 PIN domain K18828 - - 0.0000000000000000000000000000000000000000001951 166.0
SHD2_k127_2786026_0 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 437.0
SHD2_k127_2786026_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004509 259.0
SHD2_k127_2812572_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000002073 240.0
SHD2_k127_2812572_1 EamA-like transporter family - - - 0.00002937 50.0
SHD2_k127_286004_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 520.0
SHD2_k127_286004_1 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 472.0
SHD2_k127_286004_10 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 350.0
SHD2_k127_286004_11 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 335.0
SHD2_k127_286004_12 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 350.0
SHD2_k127_286004_13 Glycosyltransferase like family 2 K03606,K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 332.0
SHD2_k127_286004_14 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 300.0
SHD2_k127_286004_15 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 307.0
SHD2_k127_286004_16 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003983 286.0
SHD2_k127_286004_17 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001773 263.0
SHD2_k127_286004_18 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007959 256.0
SHD2_k127_286004_19 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000004148 248.0
SHD2_k127_286004_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 467.0
SHD2_k127_286004_20 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000005107 225.0
SHD2_k127_286004_21 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000001473 224.0
SHD2_k127_286004_22 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000002381 225.0
SHD2_k127_286004_23 Belongs to the ParA family K04562 - - 0.00000000000000000000000000000000000000000000000000000000004163 217.0
SHD2_k127_286004_24 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000001351 226.0
SHD2_k127_286004_25 histidine kinase HAMP region domain protein K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000007221 214.0
SHD2_k127_286004_26 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000004174 210.0
SHD2_k127_286004_27 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000005022 200.0
SHD2_k127_286004_28 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000002433 203.0
SHD2_k127_286004_29 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000002187 192.0
SHD2_k127_286004_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 447.0
SHD2_k127_286004_30 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000005974 184.0
SHD2_k127_286004_31 transposition, DNA-mediated K02342 - 2.7.7.7 0.000000000000000000000000000000003404 149.0
SHD2_k127_286004_32 Tetratricopeptide repeat - - - 0.000000000000000000000000001952 125.0
SHD2_k127_286004_33 peptidyl-tyrosine sulfation - - - 0.000000000000000000000001897 119.0
SHD2_k127_286004_34 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000000000000000000001012 105.0
SHD2_k127_286004_35 Belongs to the MraZ family K03925 - - 0.0000000000000000001564 95.0
SHD2_k127_286004_36 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000002917 93.0
SHD2_k127_286004_37 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563,K13626 - - 0.00000000000000008932 83.0
SHD2_k127_286004_38 Y_Y_Y domain K11527 - 2.7.13.3 0.00000000002842 78.0
SHD2_k127_286004_39 Cell division protein FtsQ K03589 - - 0.0000002546 62.0
SHD2_k127_286004_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 404.0
SHD2_k127_286004_40 translation initiation factor activity - - - 0.0008446 50.0
SHD2_k127_286004_41 antisigma factor binding - - - 0.0008567 50.0
SHD2_k127_286004_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 397.0
SHD2_k127_286004_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 344.0
SHD2_k127_286004_7 NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 340.0
SHD2_k127_286004_8 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 364.0
SHD2_k127_286004_9 Protein of unknown function (DUF2723) K16928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 355.0
SHD2_k127_2910242_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 583.0
SHD2_k127_2910242_1 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 400.0
SHD2_k127_2910242_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 378.0
SHD2_k127_2910242_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000009593 140.0
SHD2_k127_2910242_4 subfamily IA, variant 1 K08723 - 3.1.3.5 0.0000000000000000000000001747 124.0
SHD2_k127_2910242_5 Cupin 2, conserved barrel domain protein - - - 0.000000001545 69.0
SHD2_k127_2916211_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 7.857e-249 779.0
SHD2_k127_292455_0 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 472.0
SHD2_k127_292455_1 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 326.0
SHD2_k127_292455_2 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 310.0
SHD2_k127_292455_3 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000477 289.0
SHD2_k127_292455_4 - - - - 0.000000000000000000000000000000000000000000000002575 179.0
SHD2_k127_292455_5 DNA methylase K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000002283 168.0
SHD2_k127_292455_6 2 iron, 2 sulfur cluster binding - - - 0.000000000000000000000000000000002227 136.0
SHD2_k127_292455_7 - - - - 0.00000000000000000000000000001165 123.0
SHD2_k127_292455_8 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.00000000000000000000003048 116.0
SHD2_k127_292687_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 327.0
SHD2_k127_292687_1 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.0000000000000000000000000000000000006795 147.0
SHD2_k127_292687_2 SNARE associated Golgi protein - - - 0.000005198 59.0
SHD2_k127_2931524_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 370.0
SHD2_k127_2931524_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001867 282.0
SHD2_k127_2931524_2 ABC transporter, permease protein K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003493 265.0
SHD2_k127_2931524_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000001283 248.0
SHD2_k127_2931524_4 pfam abc K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000004509 245.0
SHD2_k127_2984885_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1150.0
SHD2_k127_2984885_1 BNR Asp-box repeat - - - 4.557e-217 704.0
SHD2_k127_2984885_2 DNA polymerase type-B family K02336 - 2.7.7.7 1.295e-205 666.0
SHD2_k127_2984885_3 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002035 291.0
SHD2_k127_2984885_4 AdoMet dependent proline di-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005813 289.0
SHD2_k127_2984885_5 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000956 167.0
SHD2_k127_2984885_6 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000003019 154.0
SHD2_k127_2984885_7 Belongs to the 5'-nucleotidase family - - - 0.00000000000005852 84.0
SHD2_k127_2999408_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.585e-216 679.0
SHD2_k127_2999408_1 O-methyltransferase activity - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 617.0
SHD2_k127_2999408_10 cellulose binding K00505 - 1.14.18.1 0.00000000000000001363 97.0
SHD2_k127_2999408_11 PFAM Bacterial Ig-like domain (group 2) - - - 0.0000000000000005227 92.0
SHD2_k127_2999408_12 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000003044 79.0
SHD2_k127_2999408_13 cellulose binding K00505 - 1.14.18.1 0.00000000003154 78.0
SHD2_k127_2999408_14 STAS domain K04749 - - 0.000000002622 63.0
SHD2_k127_2999408_15 PFAM Ubiquitin-conjugating - - - 0.0000002627 59.0
SHD2_k127_2999408_16 metallopeptidase activity K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000007043 55.0
SHD2_k127_2999408_17 proteolysis K03665 - - 0.00003285 55.0
SHD2_k127_2999408_18 Psort location CytoplasmicMembrane, score 9.99 - - - 0.0001609 54.0
SHD2_k127_2999408_19 Peptidase, M16 K07263 - - 0.0001942 53.0
SHD2_k127_2999408_2 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 608.0
SHD2_k127_2999408_3 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 424.0
SHD2_k127_2999408_4 PFAM Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 371.0
SHD2_k127_2999408_5 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000004134 246.0
SHD2_k127_2999408_6 PFAM EamA-like transporter family - - - 0.00000000000000000000007458 113.0
SHD2_k127_2999408_7 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00000000000000000000398 108.0
SHD2_k127_2999408_8 Bacterial Ig-like domain (group 1) - - - 0.000000000000000000005138 109.0
SHD2_k127_2999408_9 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000001254 96.0
SHD2_k127_3017_0 PFAM peptidase M13 K07386 - - 6.138e-238 793.0
SHD2_k127_3017_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 590.0
SHD2_k127_3017_2 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 374.0
SHD2_k127_3017_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000002676 85.0
SHD2_k127_3017_4 cellulose binding K00505 - 1.14.18.1 0.000000004748 63.0
SHD2_k127_303963_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 518.0
SHD2_k127_303963_1 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 349.0
SHD2_k127_303963_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 344.0
SHD2_k127_303963_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000001059 215.0
SHD2_k127_303963_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000001327 186.0
SHD2_k127_303963_5 GrpB protein - - - 0.000000000000000000000000000003805 124.0
SHD2_k127_303963_6 Response regulator, receiver - - - 0.000000000000000000000000007412 121.0
SHD2_k127_303963_7 Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family - - - 0.00000000000000000000001008 115.0
SHD2_k127_303963_8 Phosphopantetheine attachment site - - - 0.00009621 51.0
SHD2_k127_303963_9 Protein of unknown function, DUF255 K06888 - - 0.000631 52.0
SHD2_k127_3142602_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 423.0
SHD2_k127_3142602_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 382.0
SHD2_k127_3142602_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0007315 52.0
SHD2_k127_3142602_2 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002897 271.0
SHD2_k127_3142602_3 Peptidase family M1 domain K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000005183 238.0
SHD2_k127_3142602_4 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000003487 207.0
SHD2_k127_3142602_5 Acid phosphatase homologues - - - 0.00000000000000000000000000000000000001049 164.0
SHD2_k127_3142602_6 - - - - 0.0000000000000000000000000000000003052 147.0
SHD2_k127_3142602_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000004167 84.0
SHD2_k127_3142602_8 regulatory protein, FmdB family - - - 0.0000000004122 62.0
SHD2_k127_3142602_9 - - - - 0.00001306 56.0
SHD2_k127_3172182_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 598.0
SHD2_k127_3172182_1 PFAM translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000004539 94.0
SHD2_k127_318250_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.377e-268 835.0
SHD2_k127_318250_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 3.665e-209 674.0
SHD2_k127_318250_10 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 348.0
SHD2_k127_318250_11 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 348.0
SHD2_k127_318250_12 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 342.0
SHD2_k127_318250_13 helicase involved in DNA repair and perhaps also replication K02342,K03722 - 2.7.7.7,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 349.0
SHD2_k127_318250_14 Tfp pilus assembly protein pilus retraction ATPase PilT K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 304.0
SHD2_k127_318250_15 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004887 288.0
SHD2_k127_318250_16 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002315 283.0
SHD2_k127_318250_17 Type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000001157 247.0
SHD2_k127_318250_18 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001041 229.0
SHD2_k127_318250_19 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000001271 228.0
SHD2_k127_318250_2 General secretory system II protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 584.0
SHD2_k127_318250_20 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000003534 220.0
SHD2_k127_318250_21 Glycoside hydrolase family 24 - - - 0.00000000000000000000000000000000000000000000000000000007317 225.0
SHD2_k127_318250_22 Secretin and TonB N terminus short domain K02453,K02507,K02666 - - 0.0000000000000000000000000000000000000000000000000000001406 213.0
SHD2_k127_318250_23 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000001649 178.0
SHD2_k127_318250_24 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000007215 182.0
SHD2_k127_318250_25 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000001418 164.0
SHD2_k127_318250_26 hemolysin activation secretion protein K11016 - - 0.00000000000000000000000000000000001515 156.0
SHD2_k127_318250_27 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000001691 154.0
SHD2_k127_318250_28 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000003779 141.0
SHD2_k127_318250_29 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000001255 133.0
SHD2_k127_318250_3 type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 492.0
SHD2_k127_318250_30 CHAP domain - - - 0.00000000000000000000000000000007968 130.0
SHD2_k127_318250_31 membrane organization K07277 - - 0.0000000000000000000000952 113.0
SHD2_k127_318250_32 Regulatory protein, FmdB family - - - 0.0000000000000000000001546 101.0
SHD2_k127_318250_33 Pilus assembly protein, PilO K02664 - - 0.00000000000000000006313 98.0
SHD2_k127_318250_34 ABC-2 type transporter - - - 0.0000000000000002112 93.0
SHD2_k127_318250_35 Helix-hairpin-helix motif K02237 - - 0.0000000000000003276 84.0
SHD2_k127_318250_36 Tetratricopeptide repeat - - - 0.000000000000002772 90.0
SHD2_k127_318250_37 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000004827 82.0
SHD2_k127_318250_38 S-layer homology domain K01181 - 3.2.1.8 0.00000000000007204 86.0
SHD2_k127_318250_39 peptidyl-tyrosine sulfation - - - 0.00000000003931 76.0
SHD2_k127_318250_4 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 457.0
SHD2_k127_318250_40 LVIVD repeat K01179 - 3.2.1.4 0.0000000001069 75.0
SHD2_k127_318250_41 cellulase activity K01387 - 3.4.24.3 0.000000001119 72.0
SHD2_k127_318250_43 - - - - 0.000000001998 65.0
SHD2_k127_318250_44 Pilin (bacterial filament) K02650 - - 0.000000003221 64.0
SHD2_k127_318250_45 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000001675 61.0
SHD2_k127_318250_46 Tetratricopeptide repeats - - - 0.00000002104 67.0
SHD2_k127_318250_47 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000001456 64.0
SHD2_k127_318250_48 TIGRFAM general secretion pathway protein H K08084 - - 0.0000001687 59.0
SHD2_k127_318250_49 Prokaryotic N-terminal methylation motif - - - 0.0000002718 59.0
SHD2_k127_318250_5 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 451.0
SHD2_k127_318250_50 Cytochrome c554 and c-prime - - - 0.0000003785 63.0
SHD2_k127_318250_51 amine dehydrogenase activity K08884 - 2.7.11.1 0.000004104 59.0
SHD2_k127_318250_52 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000843 57.0
SHD2_k127_318250_53 Type IV pilus assembly protein PilM; K02662 - - 0.00002951 55.0
SHD2_k127_318250_54 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00003202 57.0
SHD2_k127_318250_55 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00004227 56.0
SHD2_k127_318250_57 Type IV Pilus-assembly protein W K02672 - - 0.0007678 48.0
SHD2_k127_318250_6 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 460.0
SHD2_k127_318250_7 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 433.0
SHD2_k127_318250_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 453.0
SHD2_k127_318250_9 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 378.0
SHD2_k127_3192821_0 ABC transporter K06020 - 3.6.3.25 8.244e-248 776.0
SHD2_k127_3192821_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 529.0
SHD2_k127_3192821_10 Thioredoxin - - - 0.000000000000000000000000001453 130.0
SHD2_k127_3192821_11 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000004901 83.0
SHD2_k127_3192821_12 protein secretion K09800 - - 0.00000000117 71.0
SHD2_k127_3192821_13 Protein of unknown function (DUF3494) - - - 0.000009457 57.0
SHD2_k127_3192821_2 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 334.0
SHD2_k127_3192821_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000003756 256.0
SHD2_k127_3192821_4 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001382 266.0
SHD2_k127_3192821_5 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000115 228.0
SHD2_k127_3192821_6 - - - - 0.0000000000000000000000000000000000000000000000000001262 195.0
SHD2_k127_3192821_7 MafB19-like deaminase K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.000000000000000000000000000000000000000003026 167.0
SHD2_k127_3192821_8 Hsp33 protein K04083 - - 0.00000000000000000000000000000000000003945 154.0
SHD2_k127_3192821_9 CHAT domain - - - 0.000000000000000000000000000000000003604 160.0
SHD2_k127_3193178_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 4.038e-258 829.0
SHD2_k127_3193178_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 601.0
SHD2_k127_3193178_10 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000000000000000000000000000000000000101 247.0
SHD2_k127_3193178_11 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000007391 242.0
SHD2_k127_3193178_12 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000401 215.0
SHD2_k127_3193178_13 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000001512 188.0
SHD2_k127_3193178_14 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000003844 202.0
SHD2_k127_3193178_15 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000001416 155.0
SHD2_k127_3193178_16 Acetyltransferase (GNAT) domain - - - 0.000000000000000000001281 109.0
SHD2_k127_3193178_17 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.000000000476 63.0
SHD2_k127_3193178_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 526.0
SHD2_k127_3193178_3 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 467.0
SHD2_k127_3193178_4 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 479.0
SHD2_k127_3193178_5 benzoyl-CoA reductase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 412.0
SHD2_k127_3193178_6 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 387.0
SHD2_k127_3193178_7 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 382.0
SHD2_k127_3193178_8 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 303.0
SHD2_k127_3193178_9 polyketide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 309.0
SHD2_k127_3205661_0 Evidence 5 No homology to any previously reported sequences K17713 - - 0.0000000000000000000000000000000000000000000000000001168 203.0
SHD2_k127_3205661_1 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000007965 182.0
SHD2_k127_3205661_2 cellulose binding K13735 - - 0.0000000000003255 82.0
SHD2_k127_3211022_0 Poly-gamma-glutamate hydrolase - - - 0.000000000000000000000000000000000000000007833 164.0
SHD2_k127_3211022_1 NHL repeat containing protein - - - 0.00000000000000000000002339 109.0
SHD2_k127_3211022_2 metallocarboxypeptidase activity - - - 0.00000001572 68.0
SHD2_k127_3230608_0 siderophore transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 513.0
SHD2_k127_3230608_1 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 396.0
SHD2_k127_3230608_10 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.000004201 57.0
SHD2_k127_3230608_11 Predicted membrane protein (DUF2207) - - - 0.000007118 59.0
SHD2_k127_3230608_2 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000673 254.0
SHD2_k127_3230608_3 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000002484 232.0
SHD2_k127_3230608_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000007888 138.0
SHD2_k127_3230608_5 PFAM Protein kinase K12132 - 2.7.11.1 0.00000000000000000000009496 108.0
SHD2_k127_3230608_6 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000004251 101.0
SHD2_k127_3230608_7 ubiE/COQ5 methyltransferase family - - - 0.000000000000002836 85.0
SHD2_k127_3230608_8 NfeD-like C-terminal, partner-binding - - - 0.0000004238 58.0
SHD2_k127_3230608_9 cellulase activity - - - 0.000003425 60.0
SHD2_k127_3231607_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 416.0
SHD2_k127_3231607_1 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 353.0
SHD2_k127_3231607_2 YXWGXW repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 350.0
SHD2_k127_3231607_3 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 337.0
SHD2_k127_3231607_4 protein secretion K20276 - - 0.0000000000000000000000000000000009429 153.0
SHD2_k127_3231607_5 DNA-binding transcription factor activity - - - 0.00000000000000000000000000003938 124.0
SHD2_k127_3231607_6 PFAM Response regulator receiver domain - - - 0.00000000000005213 74.0
SHD2_k127_323629_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 3.602e-256 804.0
SHD2_k127_323629_1 NADH:flavin oxidoreductase / NADH oxidase family K00354 - 1.6.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 447.0
SHD2_k127_323629_2 Glycosyl transferases group 1 - - - 0.0000000000000001842 91.0
SHD2_k127_323629_3 oxidoreductase activity - - - 0.0001367 54.0
SHD2_k127_323629_4 PFAM S-layer domain protein - - - 0.0003508 50.0
SHD2_k127_3242521_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 3.58e-230 736.0
SHD2_k127_3242521_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000005452 252.0
SHD2_k127_3242521_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000001984 111.0
SHD2_k127_3250573_2 Beta-propeller repeat - - - 0.000000000000000000000000003031 125.0
SHD2_k127_3250573_4 amine dehydrogenase activity K12287 - - 0.0000000002382 73.0
SHD2_k127_3250573_5 protein secretion - - - 0.0000000009776 70.0
SHD2_k127_3250573_6 cellulose binding - - - 0.0000001138 64.0
SHD2_k127_3250573_7 cellulose binding K00505 - 1.14.18.1 0.0000001697 60.0
SHD2_k127_3334285_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 626.0
SHD2_k127_3334285_1 Putative citrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 445.0
SHD2_k127_3334285_2 phosphate ion binding K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 437.0
SHD2_k127_3334285_3 phosphate transport system permease protein K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 411.0
SHD2_k127_3334285_4 PFAM peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002029 263.0
SHD2_k127_3334285_5 Methyltransferase domain - - - 0.000000000000000000007862 102.0
SHD2_k127_333492_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 377.0
SHD2_k127_333492_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 329.0
SHD2_k127_333492_2 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000001808 248.0
SHD2_k127_333492_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000003192 123.0
SHD2_k127_333492_4 Glycoprotease family K14742 - - 0.0000103 53.0
SHD2_k127_3369599_0 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002731 274.0
SHD2_k127_3369599_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000767 270.0
SHD2_k127_3369599_2 lipid kinase activity - - - 0.000000000000000000000000000000000000000000000000000001705 204.0
SHD2_k127_3369599_3 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000006948 161.0
SHD2_k127_3369599_4 PFAM Acid phosphatase vanadium-dependent haloperoxidase related K09775 - - 0.0000000000000000000000000000002043 129.0
SHD2_k127_3369799_0 heat shock protein binding - - - 2.722e-224 722.0
SHD2_k127_3369799_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 492.0
SHD2_k127_3369799_2 protease - - - 0.000000000000000000000000000000000000000000001442 173.0
SHD2_k127_3369799_3 Metallo-beta-lactamase domain protein - - - 0.0000000000000000000000000000000000004502 156.0
SHD2_k127_3369799_4 - - - - 0.00000000000000000000000000000000102 142.0
SHD2_k127_3369799_5 heat shock protein binding - - - 0.00000000000000000000000000000001023 149.0
SHD2_k127_3369799_6 Glutamine amidotransferases class-II - - - 0.000000000000003705 85.0
SHD2_k127_3369799_7 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000002947 76.0
SHD2_k127_3375752_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 338.0
SHD2_k127_3375752_1 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000001647 261.0
SHD2_k127_3375752_2 hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000001859 218.0
SHD2_k127_3375752_3 PSP1 C-terminal conserved region - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000008189 202.0
SHD2_k127_3375752_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000001161 191.0
SHD2_k127_3375752_5 Histidine kinase - - - 0.0000000000000000000133 102.0
SHD2_k127_3385221_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 289.0
SHD2_k127_3385221_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003188 282.0
SHD2_k127_3385221_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000286 141.0
SHD2_k127_3385221_11 - - - - 0.0000000000000000000000000000000001398 140.0
SHD2_k127_3385221_12 NmrA-like family - - - 0.0000000000000000000000000000000001493 141.0
SHD2_k127_3385221_13 N-acetyltransferase - - - 0.0000000000000000000000000003251 124.0
SHD2_k127_3385221_14 - - - - 0.000000000001502 74.0
SHD2_k127_3385221_15 Protein of unknown function (DUF1698) - - - 0.0000003058 61.0
SHD2_k127_3385221_16 protein conserved in bacteria K09923 - - 0.000003869 56.0
SHD2_k127_3385221_19 - - - - 0.0002382 50.0
SHD2_k127_3385221_2 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009809 264.0
SHD2_k127_3385221_3 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000001413 234.0
SHD2_k127_3385221_4 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K20444 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000005506 221.0
SHD2_k127_3385221_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000002836 212.0
SHD2_k127_3385221_6 DinB family - - - 0.00000000000000000000000000000000000000000000006038 175.0
SHD2_k127_3385221_7 PFAM CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000000000003503 159.0
SHD2_k127_3385221_8 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000006938 168.0
SHD2_k127_3385221_9 homoserine transmembrane transporter activity K06600,K06895 - - 0.000000000000000000000000000000000000001784 159.0
SHD2_k127_3425495_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 589.0
SHD2_k127_3425495_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 526.0
SHD2_k127_3425495_10 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000002468 152.0
SHD2_k127_3425495_11 glycosyl transferase, family 39 - - - 0.000000000000000000000000000000001742 147.0
SHD2_k127_3425495_12 Glycosyl transferase K00728 - 2.4.1.109 0.00000000000000000000000000007111 134.0
SHD2_k127_3425495_13 ribonuclease BN K07058 - - 0.000000000000000000000000003726 123.0
SHD2_k127_3425495_14 Heparinase II/III-like protein - - - 0.000000000000000000000001973 120.0
SHD2_k127_3425495_2 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 417.0
SHD2_k127_3425495_3 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 424.0
SHD2_k127_3425495_4 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 392.0
SHD2_k127_3425495_5 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000007895 247.0
SHD2_k127_3425495_6 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008816 249.0
SHD2_k127_3425495_7 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000001483 203.0
SHD2_k127_3425495_8 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000008831 188.0
SHD2_k127_3425495_9 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000003054 186.0
SHD2_k127_3425714_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 543.0
SHD2_k127_3425714_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 492.0
SHD2_k127_3425714_10 protein-disulfide reductase activity - - - 0.0000000000000000000007175 110.0
SHD2_k127_3425714_11 protein trimerization - - - 0.0000000000000002236 87.0
SHD2_k127_3425714_12 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000000006165 85.0
SHD2_k127_3425714_13 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000671 57.0
SHD2_k127_3425714_2 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 464.0
SHD2_k127_3425714_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 415.0
SHD2_k127_3425714_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 413.0
SHD2_k127_3425714_5 Polysaccharide biosynthesis protein K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 379.0
SHD2_k127_3425714_6 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 362.0
SHD2_k127_3425714_7 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 328.0
SHD2_k127_3425714_8 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000232 254.0
SHD2_k127_3425714_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000391 181.0
SHD2_k127_3438106_0 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002771 248.0
SHD2_k127_3438106_1 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000008634 140.0
SHD2_k127_3438106_2 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000002861 116.0
SHD2_k127_3438106_3 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.0000000000000000005432 90.0
SHD2_k127_3444650_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000002244 218.0
SHD2_k127_3444650_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000001369 176.0
SHD2_k127_3444650_2 - - - - 0.0000000000000000000000002578 115.0
SHD2_k127_3444650_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000162 104.0
SHD2_k127_3444650_4 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.00000000002822 74.0
SHD2_k127_3444650_5 S-layer homology domain - - - 0.0000001261 65.0
SHD2_k127_3450136_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 582.0
SHD2_k127_3450136_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 337.0
SHD2_k127_3450136_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000001261 251.0
SHD2_k127_3450136_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000001809 241.0
SHD2_k127_3450136_4 sporulation resulting in formation of a cellular spore K06381 - - 0.000000000000000000000000000000000000000000000000006906 199.0
SHD2_k127_3450136_5 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000001458 169.0
SHD2_k127_3450136_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000001459 156.0
SHD2_k127_3450136_7 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000003375 123.0
SHD2_k127_3450136_8 Methylated dna-protein cysteine methyltransferase K07443 - - 0.00000000000000000000000001226 115.0
SHD2_k127_3450136_9 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000007548 83.0
SHD2_k127_3468886_0 AcrB/AcrD/AcrF family K03296 - - 2.792e-314 994.0
SHD2_k127_3468886_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 346.0
SHD2_k127_3468886_2 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000003413 196.0
SHD2_k127_3468886_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000002251 161.0
SHD2_k127_3468886_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000009461 160.0
SHD2_k127_3468886_5 Papain family cysteine protease - - - 0.00000000000000000000000000000000006505 154.0
SHD2_k127_3468886_6 Thioredoxin - - - 0.000000000000000003521 96.0
SHD2_k127_3468886_7 Bacterial regulatory proteins, tetR family - - - 0.00000000001182 73.0
SHD2_k127_3468886_8 - - - - 0.0000000005616 72.0
SHD2_k127_3468886_9 cell redox homeostasis K03671 - - 0.0000000008854 70.0
SHD2_k127_3475848_0 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.292e-282 882.0
SHD2_k127_3475848_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 503.0
SHD2_k127_3475848_2 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 316.0
SHD2_k127_3475848_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003034 274.0
SHD2_k127_3475848_4 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000003777 225.0
SHD2_k127_3475848_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000001015 216.0
SHD2_k127_3475848_6 Secondary thiamine-phosphate synthase enzyme - - - 0.0000000000000000000000000000000000000000000000000003689 190.0
SHD2_k127_3475848_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000179 126.0
SHD2_k127_3475848_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000004617 98.0
SHD2_k127_3475848_9 Domain of unknown function (DUF1844) - - - 0.000000000000001742 80.0
SHD2_k127_3475950_0 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000002619 128.0
SHD2_k127_3476568_0 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 406.0
SHD2_k127_3476568_1 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 321.0
SHD2_k127_3476568_2 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000009625 157.0
SHD2_k127_3476568_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669,K07672 - - 0.0000000000000000000001202 111.0
SHD2_k127_3476568_4 cellulose binding - - - 0.000000000000000004637 98.0
SHD2_k127_3476568_5 pectinesterase activity K10117 - - 0.000028 57.0
SHD2_k127_3489831_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 397.0
SHD2_k127_3489831_1 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 366.0
SHD2_k127_3489831_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 346.0
SHD2_k127_3489831_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 336.0
SHD2_k127_3489831_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 316.0
SHD2_k127_3489831_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000003703 222.0
SHD2_k127_3489831_6 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000005476 206.0
SHD2_k127_3489831_7 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000001917 181.0
SHD2_k127_3508583_0 PFAM Sodium sulphate symporter K14445 - - 9.064e-228 718.0
SHD2_k127_3508583_1 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 607.0
SHD2_k127_3508583_10 - - - - 0.0000005075 62.0
SHD2_k127_3508583_11 cellulose binding - - - 0.0000005578 63.0
SHD2_k127_3508583_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00002134 52.0
SHD2_k127_3508583_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K20427 - 2.7.7.27,2.7.7.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 424.0
SHD2_k127_3508583_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 375.0
SHD2_k127_3508583_4 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 287.0
SHD2_k127_3508583_5 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000196 278.0
SHD2_k127_3508583_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003261 296.0
SHD2_k127_3508583_7 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000001064 218.0
SHD2_k127_3508583_8 Domain of unknown function (DUF4404) - - - 0.00000000000000005251 85.0
SHD2_k127_3508583_9 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 0.00000002879 63.0
SHD2_k127_3524027_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1150.0
SHD2_k127_354741_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 590.0
SHD2_k127_354741_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 505.0
SHD2_k127_354741_2 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 497.0
SHD2_k127_354741_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 378.0
SHD2_k127_354741_4 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 334.0
SHD2_k127_354741_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006522 295.0
SHD2_k127_354741_6 Bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000001061 137.0
SHD2_k127_354741_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000008233 74.0
SHD2_k127_3605149_0 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000004772 172.0
SHD2_k127_3605149_1 Biotin-protein ligase, N terminal - - - 0.000000000000000000000000000000000005736 152.0
SHD2_k127_3605149_2 Belongs to the peptidase S8 family - - - 0.0000000000000000179 97.0
SHD2_k127_3605149_3 metallopeptidase activity K01387,K01730,K20276 - 3.4.24.3,4.2.2.6 0.000001221 62.0
SHD2_k127_3645813_0 chromosome segregation K03497 - - 0.00000000000000000000000000000000007645 148.0
SHD2_k127_3645813_1 Phosphate acyltransferases K15781 - 2.3.1.51,3.1.3.3 0.0000000000000000000003764 108.0
SHD2_k127_3645813_2 - - - - 0.0000000000000732 81.0
SHD2_k127_3651842_0 Thymidylate synthase complementing protein - - - 0.0000000000000000000000000000000000000000000000000003572 192.0
SHD2_k127_3651842_1 Protein conserved in bacteria - - - 0.00000000000000002792 87.0
SHD2_k127_3651842_2 peptidyl-tyrosine sulfation - - - 0.00000000001992 78.0
SHD2_k127_3651842_3 Calx-beta domain - - - 0.000000001195 71.0
SHD2_k127_3679635_0 regulator of chromosome condensation, RCC1 - - - 0.0006832 51.0
SHD2_k127_376659_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.144e-237 763.0
SHD2_k127_376659_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.152e-218 689.0
SHD2_k127_376659_2 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 478.0
SHD2_k127_376659_3 Aldo/keto reductase family K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 441.0
SHD2_k127_376659_4 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 321.0
SHD2_k127_376659_5 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003331 291.0
SHD2_k127_376659_6 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000002386 209.0
SHD2_k127_376659_7 Putative adhesin - - - 0.00000000000000000000000000000000000007606 156.0
SHD2_k127_376659_8 ATPase activity - - - 0.000000000000000000000002498 116.0
SHD2_k127_376659_9 pectinesterase activity K10117 - - 0.0000006166 63.0
SHD2_k127_3792019_0 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000223 163.0
SHD2_k127_3792019_1 cheY-homologous receiver domain K07658 - - 0.0000000000000000000000000000000000006592 147.0
SHD2_k127_3792019_2 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000377 146.0
SHD2_k127_3792019_3 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000001028 124.0
SHD2_k127_3792019_4 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000004047 76.0
SHD2_k127_3792019_5 chitin binding K01183 - 3.2.1.14 0.0000001487 64.0
SHD2_k127_3792019_6 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01535 - 3.6.3.2,3.6.3.6 0.0001562 45.0
SHD2_k127_3865060_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 381.0
SHD2_k127_3865060_1 Recombinase zinc beta ribbon domain - - - 0.000001126 57.0
SHD2_k127_3865060_2 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00004682 47.0
SHD2_k127_3910730_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 458.0
SHD2_k127_3910730_1 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 351.0
SHD2_k127_3910730_10 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000006163 157.0
SHD2_k127_3910730_11 Peptidase M56 - - - 0.0000000000000000000000000000000000000605 158.0
SHD2_k127_3910730_12 Belongs to the ClpA ClpB family K03695,K03696 - - 0.0000000000000000000000000000000000009305 156.0
SHD2_k127_3910730_13 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000001618 124.0
SHD2_k127_3910730_14 NlpC P60 family protein - - - 0.00000000000000000000000001665 121.0
SHD2_k127_3910730_2 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 360.0
SHD2_k127_3910730_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003634 274.0
SHD2_k127_3910730_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002499 265.0
SHD2_k127_3910730_5 thymidine kinase activity K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000007035 245.0
SHD2_k127_3910730_6 Cytidine monophosphokinase K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000008216 236.0
SHD2_k127_3910730_7 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000001184 255.0
SHD2_k127_3910730_8 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000134 241.0
SHD2_k127_3910730_9 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000000000000000001204 189.0
SHD2_k127_3915218_0 alginic acid biosynthetic process - - - 0.00000002583 63.0
SHD2_k127_3915218_1 Peptidase family C25 - - - 0.0003243 53.0
SHD2_k127_3915218_2 Epidermal growth factor-like domain. - - - 0.0007176 49.0
SHD2_k127_401723_0 Ribosomal protein S1 K02945,K03527,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 2.342e-213 679.0
SHD2_k127_401723_1 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 426.0
SHD2_k127_401723_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000002161 166.0
SHD2_k127_401723_11 lipopolysaccharide metabolic process K07502,K08309,K19804,K21572 - - 0.000000000000000000000000004084 124.0
SHD2_k127_401723_12 Mut7-C RNAse domain K09122 - - 0.000000000000000000001352 102.0
SHD2_k127_401723_13 succinate dehydrogenase K00239 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 0.00001292 57.0
SHD2_k127_401723_14 PrcB C-terminal - - - 0.00003212 55.0
SHD2_k127_401723_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 347.0
SHD2_k127_401723_3 HAMP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009564 291.0
SHD2_k127_401723_4 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001388 269.0
SHD2_k127_401723_5 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000002285 222.0
SHD2_k127_401723_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000002669 227.0
SHD2_k127_401723_7 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000001709 209.0
SHD2_k127_401723_8 succinate dehydrogenase K00241 - - 0.0000000000000000000000000000000000000000000000003281 183.0
SHD2_k127_401723_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000007914 168.0
SHD2_k127_4030569_0 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 541.0
SHD2_k127_4030569_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000001145 234.0
SHD2_k127_4036271_0 PFAM Enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000002806 235.0
SHD2_k127_4036271_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000006686 169.0
SHD2_k127_4036271_2 3-hydroxyacyl-CoA dehydrogenase K00074 GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.1.1.157 0.00000000000001953 73.0
SHD2_k127_4036271_3 Receptor family ligand binding region K01999 - - 0.000000002124 62.0
SHD2_k127_4058706_0 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 523.0
SHD2_k127_4058706_1 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 388.0
SHD2_k127_4058706_10 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000004788 72.0
SHD2_k127_4058706_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 370.0
SHD2_k127_4058706_3 Bacterial regulatory protein, Fis family K02584 - - 0.000000000000000000000000000000000000000000000000006385 201.0
SHD2_k127_4058706_4 Glycine oxidase K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 0.00000000000000000000000000000000000000003033 166.0
SHD2_k127_4058706_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000002126 153.0
SHD2_k127_4058706_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000006874 147.0
SHD2_k127_4058706_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000004012 136.0
SHD2_k127_4058706_8 Belongs to the peptidase S8 family - - - 0.000000000000000005989 98.0
SHD2_k127_4058706_9 ThiS family K03154 - - 0.0000000000004194 81.0
SHD2_k127_4073608_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 516.0
SHD2_k127_4073608_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000003011 235.0
SHD2_k127_4073608_10 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000002183 67.0
SHD2_k127_4073608_11 peptidyl-tyrosine sulfation - - - 0.0000001002 64.0
SHD2_k127_4073608_12 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00009182 55.0
SHD2_k127_4073608_13 Histidine Phosphotransfer domain - - - 0.0002709 52.0
SHD2_k127_4073608_14 Cytochrome c - - - 0.0005401 43.0
SHD2_k127_4073608_2 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000003945 222.0
SHD2_k127_4073608_3 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000004841 200.0
SHD2_k127_4073608_4 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000003101 176.0
SHD2_k127_4073608_5 Encoded by - - - 0.000000000000000000000000000000000000000007942 166.0
SHD2_k127_4073608_6 CYTH domain - - - 0.00000000000000000000000000000003748 132.0
SHD2_k127_4073608_7 lipid a biosynthesis - - - 0.0000000000000000000000000009294 125.0
SHD2_k127_4073608_8 Gram-negative-bacterium-type cell outer membrane assembly - - - 0.00000000000000000000005047 103.0
SHD2_k127_4073608_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000001381 80.0
SHD2_k127_4078395_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - 2.093e-306 974.0
SHD2_k127_4078395_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 1.231e-228 719.0
SHD2_k127_4078395_10 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000001209 185.0
SHD2_k127_4078395_11 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000004123 156.0
SHD2_k127_4078395_12 Peptidase family M48 - - - 0.000000000000000000000000000006262 136.0
SHD2_k127_4078395_13 - - - - 0.00000000000001043 87.0
SHD2_k127_4078395_14 Domain of unknown function (DUF222) K07451 - - 0.0000005349 58.0
SHD2_k127_4078395_15 Prokaryotic N-terminal methylation motif - - - 0.000004905 57.0
SHD2_k127_4078395_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 447.0
SHD2_k127_4078395_3 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 397.0
SHD2_k127_4078395_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 333.0
SHD2_k127_4078395_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 280.0
SHD2_k127_4078395_6 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008678 269.0
SHD2_k127_4078395_7 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001893 251.0
SHD2_k127_4078395_8 Domain of unknown function (DUF4912) K09942 - - 0.0000000000000000000000000000000000000000000000000000000001466 222.0
SHD2_k127_4078395_9 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000002309 200.0
SHD2_k127_409297_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 5.598e-270 841.0
SHD2_k127_4101596_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 463.0
SHD2_k127_4101596_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 390.0
SHD2_k127_4101596_10 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000001406 86.0
SHD2_k127_4101596_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002746 263.0
SHD2_k127_4101596_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000001701 217.0
SHD2_k127_4101596_4 PFAM Ribulose-phosphate 3-epimerase K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000003481 193.0
SHD2_k127_4101596_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000008161 174.0
SHD2_k127_4101596_6 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000009858 114.0
SHD2_k127_4101596_7 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000001069 118.0
SHD2_k127_4101596_8 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000309 91.0
SHD2_k127_4101596_9 Ribosomal protein S16 K02959 - - 0.0000000000000000007138 89.0
SHD2_k127_4110374_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 4.486e-205 647.0
SHD2_k127_4110374_1 helicase superfamily c-terminal domain K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 469.0
SHD2_k127_4110374_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 399.0
SHD2_k127_4110374_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000141 246.0
SHD2_k127_4110374_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000006552 208.0
SHD2_k127_4110374_5 Binds the 23S rRNA K02909 - - 0.000000000000000000000002674 108.0
SHD2_k127_4110374_6 pyrroloquinoline quinone binding K12349 - 3.5.1.23 0.00000000000000000000009184 115.0
SHD2_k127_4110374_7 Elongation factor SelB, winged helix K03833 - - 0.0000001166 54.0
SHD2_k127_4110374_8 Tetratricopeptide repeat - - - 0.00003382 57.0
SHD2_k127_4112754_0 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 351.0
SHD2_k127_4112754_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007468 285.0
SHD2_k127_4112754_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000752 272.0
SHD2_k127_4112754_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000001373 166.0
SHD2_k127_4112754_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000002472 149.0
SHD2_k127_4112754_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000001311 143.0
SHD2_k127_4112754_6 SAM-dependent methyltransferase - - - 0.000000000000000000000000000000003651 147.0
SHD2_k127_4112754_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000403 126.0
SHD2_k127_4112754_8 Bacterial Ig-like domain - - - 0.0000000116 67.0
SHD2_k127_4112754_9 Binds directly to 16S ribosomal RNA K02968 - - 0.0000001717 58.0
SHD2_k127_4161630_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 593.0
SHD2_k127_4161630_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 531.0
SHD2_k127_4161630_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 418.0
SHD2_k127_4161630_3 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 392.0
SHD2_k127_4161630_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 345.0
SHD2_k127_4161630_5 NADH dehydrogenase (quinone) activity K03943 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0007399,GO:0007507,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009888,GO:0009987,GO:0010257,GO:0014706,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048513,GO:0048731,GO:0048738,GO:0048856,GO:0050136,GO:0055086,GO:0055114,GO:0060537,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072359,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000008905 157.0
SHD2_k127_4161630_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000003262 167.0
SHD2_k127_4161630_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000002363 138.0
SHD2_k127_4161630_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000001255 98.0
SHD2_k127_4161630_9 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000001581 93.0
SHD2_k127_4233783_0 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 518.0
SHD2_k127_4233783_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 387.0
SHD2_k127_4233783_10 Methyltransferase domain - - - 0.00000000000000000001393 102.0
SHD2_k127_4233783_11 Cupredoxin-like domain - - - 0.00000000000003222 78.0
SHD2_k127_4233783_2 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 307.0
SHD2_k127_4233783_3 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002665 263.0
SHD2_k127_4233783_4 Glucose inhibited division protein A K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000008838 256.0
SHD2_k127_4233783_5 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000001417 212.0
SHD2_k127_4233783_6 3-hydroxyacyl-CoA dehydrogenase K00074 GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.1.1.157 0.000000000000000000000000000000000000000000000002288 199.0
SHD2_k127_4233783_7 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519,K18021 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.5.3,1.2.99.8 0.00000000000000000000000000000007643 130.0
SHD2_k127_4233783_8 YceI-like domain - - - 0.000000000000000000000000000005309 130.0
SHD2_k127_4233783_9 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000002779 107.0
SHD2_k127_4241345_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000007667 77.0
SHD2_k127_4241345_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0002001 48.0
SHD2_k127_4251865_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 6.849e-197 624.0
SHD2_k127_4251865_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 336.0
SHD2_k127_4251865_10 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000002906 166.0
SHD2_k127_4251865_11 Glycosyltransferase Family 4 - - - 0.0000000000000000000002384 106.0
SHD2_k127_4251865_12 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000001312 109.0
SHD2_k127_4251865_13 - - - - 0.0005528 49.0
SHD2_k127_4251865_2 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 309.0
SHD2_k127_4251865_3 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006701 292.0
SHD2_k127_4251865_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006482 286.0
SHD2_k127_4251865_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 278.0
SHD2_k127_4251865_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001141 270.0
SHD2_k127_4251865_7 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000009292 240.0
SHD2_k127_4251865_8 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000003802 248.0
SHD2_k127_4251865_9 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000002234 218.0
SHD2_k127_4275457_0 Peptidase family M1 domain K01992 - - 0.0 1216.0
SHD2_k127_4275457_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 507.0
SHD2_k127_4275457_10 Transcriptional regulatory protein, C terminal K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000006861 219.0
SHD2_k127_4275457_11 COGs COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.000000000000000000000000000000000000000000000000653 184.0
SHD2_k127_4275457_12 PFAM ATP-binding region, ATPase domain protein K07651 - 2.7.13.3 0.000000000000000000000000000000000000000000000005438 191.0
SHD2_k127_4275457_13 COG0822 NifU homolog involved in Fe-S cluster formation K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.0000000000000000000000000000000001091 145.0
SHD2_k127_4275457_14 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000021 113.0
SHD2_k127_4275457_15 of nitrite reductase and ring-hydroxylating K05710 - - 0.0000000000000000000006325 96.0
SHD2_k127_4275457_16 Pfam:DUF59 K02612 - - 0.0000000000000000001167 97.0
SHD2_k127_4275457_17 Domain of Unknown Function with PDB structure (DUF3858) - - - 0.000000000000001771 91.0
SHD2_k127_4275457_18 Domain of unknown function (DUF4154) - - - 0.000000000004421 75.0
SHD2_k127_4275457_19 Domain of unknown function (DUF4154) - - - 0.00000008327 61.0
SHD2_k127_4275457_2 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 426.0
SHD2_k127_4275457_3 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 410.0
SHD2_k127_4275457_4 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 411.0
SHD2_k127_4275457_5 (ABC) transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 384.0
SHD2_k127_4275457_6 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 373.0
SHD2_k127_4275457_7 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 359.0
SHD2_k127_4275457_8 PFAM ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 291.0
SHD2_k127_4275457_9 PFAM RNA binding S1 domain protein K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006874 278.0
SHD2_k127_4284441_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.701e-226 733.0
SHD2_k127_4284441_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.429e-219 701.0
SHD2_k127_4284441_10 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 306.0
SHD2_k127_4284441_11 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001401 259.0
SHD2_k127_4284441_12 Male sterility protein K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000003592 211.0
SHD2_k127_4284441_13 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000297 208.0
SHD2_k127_4284441_14 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000004358 203.0
SHD2_k127_4284441_15 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000818 175.0
SHD2_k127_4284441_16 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000001283 145.0
SHD2_k127_4284441_17 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000002604 139.0
SHD2_k127_4284441_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000153 143.0
SHD2_k127_4284441_19 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000109 128.0
SHD2_k127_4284441_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 476.0
SHD2_k127_4284441_20 Could be involved in septation K06412 - - 0.00000000000000000000000005076 109.0
SHD2_k127_4284441_21 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001059 106.0
SHD2_k127_4284441_22 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000001095 96.0
SHD2_k127_4284441_23 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000001592 94.0
SHD2_k127_4284441_24 peptidyl-prolyl isomerase K07533 - 5.2.1.8 0.00000000000001177 86.0
SHD2_k127_4284441_25 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000001539 78.0
SHD2_k127_4284441_26 Regulatory protein recX K03565 - - 0.00000008389 65.0
SHD2_k127_4284441_27 protein trimerization - - - 0.00001923 57.0
SHD2_k127_4284441_28 repeat-containing protein - - - 0.00002817 57.0
SHD2_k127_4284441_3 SMC proteins Flexible Hinge Domain K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 498.0
SHD2_k127_4284441_4 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 434.0
SHD2_k127_4284441_5 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 370.0
SHD2_k127_4284441_6 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 351.0
SHD2_k127_4284441_7 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 365.0
SHD2_k127_4284441_8 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 344.0
SHD2_k127_4284441_9 ABC transporter, ATP-binding protein K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 304.0
SHD2_k127_431409_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.603e-242 774.0
SHD2_k127_431409_1 DNA polymerase K02337,K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 548.0
SHD2_k127_431409_10 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000753 175.0
SHD2_k127_431409_11 - - - - 0.0000000000000000000000000000000000000005692 157.0
SHD2_k127_431409_12 Cytochrome C assembly protein - - - 0.00000000000000000000000000000003964 136.0
SHD2_k127_431409_13 - - - - 0.00000000000000000000000005007 121.0
SHD2_k127_431409_14 Uncharacterized protein family UPF0016 - - - 0.000000000000000002427 89.0
SHD2_k127_431409_15 Uroporphyrinogen-III synthase HemD K13542 - 2.1.1.107,4.2.1.75 0.000000309 55.0
SHD2_k127_431409_16 sporulation resulting in formation of a cellular spore - - - 0.0003798 44.0
SHD2_k127_431409_2 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 514.0
SHD2_k127_431409_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 448.0
SHD2_k127_431409_4 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 449.0
SHD2_k127_431409_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 371.0
SHD2_k127_431409_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 359.0
SHD2_k127_431409_7 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000519 289.0
SHD2_k127_431409_8 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001471 258.0
SHD2_k127_431409_9 - - - - 0.00000000000000000000000000000000000000000000000004463 197.0
SHD2_k127_4332618_0 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 396.0
SHD2_k127_4332618_1 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 400.0
SHD2_k127_4332618_2 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006558 274.0
SHD2_k127_4332618_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000009221 225.0
SHD2_k127_4332618_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000003475 193.0
SHD2_k127_4332618_5 protein conserved in bacteria - - - 0.000000000000000000005435 107.0
SHD2_k127_4332618_6 Trypsin-like serine protease K01337 - 3.4.21.50 0.0000000000002056 84.0
SHD2_k127_4332618_7 DnaJ domain protein K05801 - - 0.000008721 57.0
SHD2_k127_4337938_0 Peptidase family M1 domain K01256,K08776 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 556.0
SHD2_k127_4337938_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 380.0
SHD2_k127_4337938_10 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000007458 137.0
SHD2_k127_4337938_11 Cache domain - - - 0.0000000000000001981 90.0
SHD2_k127_4337938_12 DUF167 - - - 0.000000000000003178 79.0
SHD2_k127_4337938_13 - - - - 0.0000000001766 65.0
SHD2_k127_4337938_2 DNA methyltransferase K07318 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 365.0
SHD2_k127_4337938_3 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000667 288.0
SHD2_k127_4337938_4 major pilin protein fima - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001213 290.0
SHD2_k127_4337938_5 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003464 278.0
SHD2_k127_4337938_6 PFAM tRNA pseudouridine synthase D TruD K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000002117 258.0
SHD2_k127_4337938_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000001868 248.0
SHD2_k127_4337938_8 Peroxiredoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000002175 204.0
SHD2_k127_4337938_9 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000002413 202.0
SHD2_k127_4342429_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 315.0
SHD2_k127_4342429_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000006719 240.0
SHD2_k127_4342429_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000003672 100.0
SHD2_k127_4342429_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000005042 94.0
SHD2_k127_4342429_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000001156 84.0
SHD2_k127_4342429_5 PFAM SpoVT AbrB like domain K07172 - - 0.00000000000001689 74.0
SHD2_k127_4342429_6 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000313 55.0
SHD2_k127_4367231_0 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 394.0
SHD2_k127_4367231_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 351.0
SHD2_k127_4367231_2 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 310.0
SHD2_k127_4373025_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1279.0
SHD2_k127_4373025_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 1.706e-242 780.0
SHD2_k127_4373025_10 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 343.0
SHD2_k127_4373025_11 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 312.0
SHD2_k127_4373025_12 PFAM peptidase S58, DmpA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 317.0
SHD2_k127_4373025_13 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 322.0
SHD2_k127_4373025_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 310.0
SHD2_k127_4373025_15 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 296.0
SHD2_k127_4373025_16 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002205 284.0
SHD2_k127_4373025_17 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003344 269.0
SHD2_k127_4373025_18 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006442 259.0
SHD2_k127_4373025_19 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001358 269.0
SHD2_k127_4373025_2 Tricorn protease C1 domain K08676 - - 1.305e-216 737.0
SHD2_k127_4373025_20 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000005462 254.0
SHD2_k127_4373025_21 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000127 233.0
SHD2_k127_4373025_22 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000002021 231.0
SHD2_k127_4373025_23 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000422 225.0
SHD2_k127_4373025_24 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000002778 233.0
SHD2_k127_4373025_25 PFAM HhH-GPD K07457 - - 0.00000000000000000000000000000000000000000000000000004105 202.0
SHD2_k127_4373025_26 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000005475 204.0
SHD2_k127_4373025_27 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000002543 195.0
SHD2_k127_4373025_28 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000294 206.0
SHD2_k127_4373025_29 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08256 - 2.4.1.345,2.7.8.5 0.000000000000000000000000000000000000000000000000003494 206.0
SHD2_k127_4373025_3 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 614.0
SHD2_k127_4373025_30 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000009462 190.0
SHD2_k127_4373025_31 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000481 171.0
SHD2_k127_4373025_32 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000001049 164.0
SHD2_k127_4373025_33 PFAM Beta-lactamase - - - 0.00000000000000000000001485 113.0
SHD2_k127_4373025_35 -O-antigen K18814 - - 0.0000000000000000007182 100.0
SHD2_k127_4373025_36 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000004381 88.0
SHD2_k127_4373025_37 Bacterial regulatory proteins, tetR family - - - 0.00000000003729 71.0
SHD2_k127_4373025_38 TIGRFAM TIGR03032 family protein - - - 0.000000001945 72.0
SHD2_k127_4373025_39 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000003062 66.0
SHD2_k127_4373025_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 596.0
SHD2_k127_4373025_40 Methyltransferase domain K14374,K18896 - 2.1.1.156 0.0000002029 61.0
SHD2_k127_4373025_41 extracellular matrix structural constituent - - - 0.0000009967 62.0
SHD2_k127_4373025_42 - - - - 0.0000178 55.0
SHD2_k127_4373025_43 to plant photosystem II stability assembly factor - - - 0.0001917 55.0
SHD2_k127_4373025_44 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001918 54.0
SHD2_k127_4373025_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 440.0
SHD2_k127_4373025_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 389.0
SHD2_k127_4373025_7 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 353.0
SHD2_k127_4373025_8 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 334.0
SHD2_k127_4373025_9 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 331.0
SHD2_k127_4381378_0 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000362 194.0
SHD2_k127_4381378_1 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000001666 86.0
SHD2_k127_4396794_0 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 312.0
SHD2_k127_4396794_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000008251 173.0
SHD2_k127_4396794_2 Transcriptional regulator - - - 0.00000000000008397 82.0
SHD2_k127_4397116_0 Evidence 5 No homology to any previously reported sequences K17713 - - 0.00000000000000000000005166 115.0
SHD2_k127_4397116_1 - - - - 0.000000000000002394 87.0
SHD2_k127_4402084_0 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 492.0
SHD2_k127_4402084_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005706 293.0
SHD2_k127_4402084_2 Histidine kinase K02480 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000127 222.0
SHD2_k127_4402084_3 Cation efflux family - - - 0.000000000000000000000000000000000000000000000106 189.0
SHD2_k127_4402084_4 Domain of unknown function (DUF4403) - - - 0.00000000000000000008822 94.0
SHD2_k127_4402084_5 Histidine kinase - - - 0.000000001802 72.0
SHD2_k127_440432_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 563.0
SHD2_k127_440432_1 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.0000000000000000000002953 109.0
SHD2_k127_440432_2 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.0000000000000000007733 100.0
SHD2_k127_440432_3 Protein conserved in bacteria - - - 0.000000000000008399 85.0
SHD2_k127_440432_4 COG1956 GAF domain-containing protein K08968 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0033745,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.8.4.14 0.00000002989 65.0
SHD2_k127_4410585_0 SMART serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 469.0
SHD2_k127_4410585_1 Histidine kinase - - - 0.00000000000000000000000000000001139 141.0
SHD2_k127_4410585_2 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000001146 96.0
SHD2_k127_4423745_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1028.0
SHD2_k127_4423745_1 DNA topoisomerase II activity K02469 - 5.99.1.3 7.335e-316 989.0
SHD2_k127_4423745_10 Methanol dehydrogenase K06872 - - 0.00000000000000000000000000000001196 139.0
SHD2_k127_4423745_11 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000001414 118.0
SHD2_k127_4423745_12 PFAM Peptidase family M23 K21471 - - 0.00000000000000000000002454 112.0
SHD2_k127_4423745_13 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000007678 101.0
SHD2_k127_4423745_14 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001812 70.0
SHD2_k127_4423745_15 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000001977 81.0
SHD2_k127_4423745_16 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000009715 73.0
SHD2_k127_4423745_17 Protein of unknown function (DUF721) - - - 0.000000005892 62.0
SHD2_k127_4423745_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.584e-273 871.0
SHD2_k127_4423745_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 409.0
SHD2_k127_4423745_4 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 290.0
SHD2_k127_4423745_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.0000000000000000000000000000000000000000000000000000000000000000000000006874 267.0
SHD2_k127_4423745_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000008288 245.0
SHD2_k127_4423745_7 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000006223 237.0
SHD2_k127_4423745_8 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000006749 197.0
SHD2_k127_4423745_9 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000002276 147.0
SHD2_k127_4449459_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000002752 240.0
SHD2_k127_4449459_1 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000005295 107.0
SHD2_k127_4449459_2 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.000000000000004402 85.0
SHD2_k127_4449459_3 STAS domain K04749 - - 0.00000000000004822 76.0
SHD2_k127_4451047_0 aminopeptidase K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 446.0
SHD2_k127_4451047_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000001375 204.0
SHD2_k127_4451047_10 homoserine transmembrane transporter activity K06600,K06895 - - 0.00000015 64.0
SHD2_k127_4451047_12 cytochrome complex assembly K02198,K02200,K04018,K19225,K20543,K21007 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 3.4.21.105 0.00001828 56.0
SHD2_k127_4451047_2 Glycosyl Transferase - - - 0.00000000000000000000000000000000000000000000000000001393 209.0
SHD2_k127_4451047_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000002212 175.0
SHD2_k127_4451047_4 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000000000000000000001507 155.0
SHD2_k127_4451047_5 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000001066 157.0
SHD2_k127_4451047_6 PAP2 superfamily - - - 0.000000000000000000000001139 113.0
SHD2_k127_4451047_7 Glycosyl transferases group 1 - - - 0.0000000000000000000001676 112.0
SHD2_k127_4451047_8 metallopeptidase activity K01181,K05994 - 3.2.1.8,3.4.11.10 0.00000000000000000004067 106.0
SHD2_k127_4451047_9 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.00000000003752 71.0
SHD2_k127_4456498_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 348.0
SHD2_k127_4456498_1 Peptidase family M28 - - - 0.0000005593 55.0
SHD2_k127_4459426_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 603.0
SHD2_k127_4459426_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 359.0
SHD2_k127_4459426_10 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000007978 176.0
SHD2_k127_4459426_11 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000003544 177.0
SHD2_k127_4459426_12 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000002163 168.0
SHD2_k127_4459426_13 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002778 147.0
SHD2_k127_4459426_14 Zinc metalloprotease (Elastase) - - - 0.0000000000000000000000000000003557 143.0
SHD2_k127_4459426_15 extracellular matrix structural constituent - - - 0.0000000000000000004823 103.0
SHD2_k127_4459426_16 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000002917 98.0
SHD2_k127_4459426_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 328.0
SHD2_k127_4459426_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008417 307.0
SHD2_k127_4459426_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 299.0
SHD2_k127_4459426_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 296.0
SHD2_k127_4459426_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 297.0
SHD2_k127_4459426_7 Ribosome recycling factor K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000168 216.0
SHD2_k127_4459426_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000001922 204.0
SHD2_k127_4459426_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000699 179.0
SHD2_k127_4502861_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 387.0
SHD2_k127_4502861_1 cellulose binding - - - 0.0000009184 62.0
SHD2_k127_4573551_0 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 389.0
SHD2_k127_4573551_1 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 314.0
SHD2_k127_4573551_2 helix_turn_helix multiple antibiotic resistance protein K15973 - - 0.000000000000000000000000000000000000000006103 159.0
SHD2_k127_4573551_3 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000003487 142.0
SHD2_k127_4573551_4 - - - - 0.00000000000000000000000000000003959 133.0
SHD2_k127_4575579_0 tryptophanase activity K01667 - 4.1.99.1 4.238e-196 621.0
SHD2_k127_4575579_1 FlgD Ig-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 617.0
SHD2_k127_4575579_10 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000008106 230.0
SHD2_k127_4575579_11 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000001077 212.0
SHD2_k127_4575579_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000502 218.0
SHD2_k127_4575579_13 Zinc metalloprotease (Elastase) - - - 0.0000000000000000000000000000000000000000000000000005209 212.0
SHD2_k127_4575579_14 peptidase activity, acting on L-amino acid peptides K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000004675 196.0
SHD2_k127_4575579_15 aminopeptidase activity - - - 0.000000000000000000000000000000000002096 161.0
SHD2_k127_4575579_16 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000003457 137.0
SHD2_k127_4575579_17 COGs COG1629 Outer membrane receptor protein mostly Fe transport - - - 0.0000000000000000000000000000006583 137.0
SHD2_k127_4575579_18 Belongs to the Fur family K09825,K22297 - - 0.000000000000000000000000002349 117.0
SHD2_k127_4575579_19 Ferredoxin - - - 0.00000000000103 73.0
SHD2_k127_4575579_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 535.0
SHD2_k127_4575579_20 Trypsin-like serine protease K01337 - 3.4.21.50 0.0000000000042 79.0
SHD2_k127_4575579_21 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000004293 63.0
SHD2_k127_4575579_3 TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 393.0
SHD2_k127_4575579_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 380.0
SHD2_k127_4575579_5 DHH family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003325 276.0
SHD2_k127_4575579_6 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001804 277.0
SHD2_k127_4575579_7 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000001191 243.0
SHD2_k127_4575579_8 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001599 273.0
SHD2_k127_4575579_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000001017 248.0
SHD2_k127_4590223_0 Belongs to the carbamoyltransferase HypF family K04656 - - 8.29e-218 702.0
SHD2_k127_4590223_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 488.0
SHD2_k127_4590223_10 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000002095 224.0
SHD2_k127_4590223_11 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.0000000000000000000000000000000000000000000000000003427 207.0
SHD2_k127_4590223_12 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000002317 177.0
SHD2_k127_4590223_13 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.00000000000000000000000000000000000000002539 160.0
SHD2_k127_4590223_14 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000000006911 111.0
SHD2_k127_4590223_15 Hydrogenase maturation protease K08315 - 3.4.23.51 0.00000000000000000002212 106.0
SHD2_k127_4590223_16 hydrogen uptake protein K03605 - - 0.0000000000004816 79.0
SHD2_k127_4590223_17 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000002415 73.0
SHD2_k127_4590223_18 Histidine kinase - - - 0.0007209 48.0
SHD2_k127_4590223_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 479.0
SHD2_k127_4590223_3 Proton-conducting membrane transporter K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 472.0
SHD2_k127_4590223_4 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 452.0
SHD2_k127_4590223_5 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K12139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 384.0
SHD2_k127_4590223_6 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 296.0
SHD2_k127_4590223_7 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003807 282.0
SHD2_k127_4590223_8 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007092 272.0
SHD2_k127_4590223_9 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000191 249.0
SHD2_k127_4614784_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 556.0
SHD2_k127_4614784_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 347.0
SHD2_k127_4614784_10 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000001515 57.0
SHD2_k127_4614784_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000003403 248.0
SHD2_k127_4614784_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001787 207.0
SHD2_k127_4614784_4 riboflavin synthase alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000002482 188.0
SHD2_k127_4614784_5 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000001568 196.0
SHD2_k127_4614784_6 Protein of unknown function (DUF2723) K16928 - - 0.000000000000000000000000000000000000000000000001164 197.0
SHD2_k127_4614784_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000017 172.0
SHD2_k127_4614784_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000002286 94.0
SHD2_k127_4614784_9 Bacterial Ig-like domain (group 3) K20276 - - 0.000000001336 73.0
SHD2_k127_464597_0 arsenical-resistance protein K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 477.0
SHD2_k127_464597_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000001325 209.0
SHD2_k127_464597_2 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000004753 132.0
SHD2_k127_464597_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000006298 84.0
SHD2_k127_464597_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000002924 53.0
SHD2_k127_4671000_0 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 331.0
SHD2_k127_4671000_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000001456 192.0
SHD2_k127_4671000_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000001352 72.0
SHD2_k127_4671000_11 O-Antigen ligase - - - 0.0000001857 64.0
SHD2_k127_4671000_2 - - - - 0.000000000000000000000000000000000000000000005074 179.0
SHD2_k127_4671000_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000003294 173.0
SHD2_k127_4671000_4 extracellular polysaccharide biosynthetic process K01153,K05789,K07011,K16554 - 3.1.21.3 0.0000000000000000000000000000000000000139 164.0
SHD2_k127_4671000_5 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000003394 164.0
SHD2_k127_4671000_6 AAA domain - - - 0.0000000000000000000000000000000000004487 163.0
SHD2_k127_4671000_7 Polysaccharide biosynthesis C-terminal domain - - - 0.00000000000000000000000000000773 138.0
SHD2_k127_4671000_8 Calcineurin-like phosphoesterase K03547 - - 0.00000000000000000000001181 111.0
SHD2_k127_4671000_9 Heparinase II - - - 0.000000000628 68.0
SHD2_k127_4686537_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 9.425e-255 796.0
SHD2_k127_4686537_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 355.0
SHD2_k127_4686537_2 Outer membrane efflux protein - - - 0.000001302 55.0
SHD2_k127_4705730_0 Tetratricopeptide repeat - - - 0.0000000000000000000004095 112.0
SHD2_k127_4705730_1 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000006275 103.0
SHD2_k127_4705730_2 WD-40 repeat - - - 0.000000000000485 82.0
SHD2_k127_4705730_3 Belongs to the peptidase S8 family K06113,K12685 - 3.2.1.99 0.000000008237 68.0
SHD2_k127_4705730_4 - - - - 0.00000001597 66.0
SHD2_k127_4705730_5 - - - - 0.000002714 61.0
SHD2_k127_4714252_0 - - - - 0.0000000000000000000000000000000002603 144.0
SHD2_k127_4714252_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000001553 57.0
SHD2_k127_4727608_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000001901 134.0
SHD2_k127_4727608_1 chalcone and stilbene synthase domain protein - - - 0.0000000000000000000007096 100.0
SHD2_k127_4727608_2 - - - - 0.00000008285 55.0
SHD2_k127_47289_0 PFAM Uncharacterised protein family (UPF0164) - - - 0.00000000000000000000000000000000000000000000000000005143 197.0
SHD2_k127_47289_1 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000599 150.0
SHD2_k127_4755757_0 Amidase K01426 - 3.5.1.4 5.902e-213 677.0
SHD2_k127_4755757_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 485.0
SHD2_k127_4755757_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 437.0
SHD2_k127_4755757_3 translation elongation factor activity K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000004449 205.0
SHD2_k127_4755757_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000004353 192.0
SHD2_k127_4755757_5 iron-sulfur cluster assembly K07400 - - 0.0000000000000000000000000000000000000003112 164.0
SHD2_k127_4755757_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000005959 157.0
SHD2_k127_4755757_7 PEP-CTERM motif - - - 0.0002252 49.0
SHD2_k127_4810765_0 PFAM MgsA AAA ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 420.0
SHD2_k127_4810765_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
SHD2_k127_4810765_2 - - - - 0.000009161 49.0
SHD2_k127_485187_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 2.682e-282 889.0
SHD2_k127_485187_1 lyase activity K01387,K03301 - 3.4.24.3 0.000000000000000000000000000000000000000000000000003315 206.0
SHD2_k127_4854531_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.497e-223 706.0
SHD2_k127_4854531_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 494.0
SHD2_k127_4854531_10 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000001789 121.0
SHD2_k127_4854531_11 - - - - 0.0000000000000000007831 91.0
SHD2_k127_4854531_12 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000004693 77.0
SHD2_k127_4854531_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000003034 64.0
SHD2_k127_4854531_14 TIGRFAM cell envelope-related function transcriptional attenuator - - - 0.000004213 55.0
SHD2_k127_4854531_15 calcium ion binding K17307 - - 0.00004733 56.0
SHD2_k127_4854531_16 Sec-independent protein translocase protein (TatC) K03118 - - 0.0001233 46.0
SHD2_k127_4854531_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 298.0
SHD2_k127_4854531_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004617 264.0
SHD2_k127_4854531_4 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000003639 248.0
SHD2_k127_4854531_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000001256 235.0
SHD2_k127_4854531_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000004382 221.0
SHD2_k127_4854531_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000002771 162.0
SHD2_k127_4854531_8 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000001776 149.0
SHD2_k127_4854531_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000001308 118.0
SHD2_k127_4870506_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 370.0
SHD2_k127_4870506_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000007267 193.0
SHD2_k127_4870506_2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000002254 141.0
SHD2_k127_4870506_3 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000001484 115.0
SHD2_k127_4870506_4 RNA-binding protein - - - 0.0000000000000000000001197 102.0
SHD2_k127_4870506_5 Major facilitator Superfamily - - - 0.00000008431 64.0
SHD2_k127_4874999_0 lipolytic protein G-D-S-L family K00612 - - 0.000000000000000000000000000000001222 144.0
SHD2_k127_4879356_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 409.0
SHD2_k127_4888873_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 567.0
SHD2_k127_4888873_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 448.0
SHD2_k127_4888873_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000001036 201.0
SHD2_k127_4888873_3 BON domain - - - 0.0000000000005216 79.0
SHD2_k127_4891885_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 471.0
SHD2_k127_4891885_1 PFAM Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000000000000000000000002067 201.0
SHD2_k127_4891885_2 RNA recognition motif - - - 0.000000000000000000000000000000000000000611 152.0
SHD2_k127_4891885_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000002166 72.0
SHD2_k127_4892638_0 NAD binding K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 502.0
SHD2_k127_4892638_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 372.0
SHD2_k127_4892638_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.0000000000000000000000000000000000007024 144.0
SHD2_k127_4892638_11 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000005028 113.0
SHD2_k127_4892638_12 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000109 109.0
SHD2_k127_4892638_13 Transglutaminase-like superfamily - - - 0.00000000000000000003329 106.0
SHD2_k127_4892638_2 Subtilase family K13276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 355.0
SHD2_k127_4892638_3 Subtilase family K13276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 341.0
SHD2_k127_4892638_4 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003134 289.0
SHD2_k127_4892638_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001337 237.0
SHD2_k127_4892638_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000216 166.0
SHD2_k127_4892638_7 SMART protein phosphatase 2C domain protein K20074 GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 0.00000000000000000000000000000000000000003303 163.0
SHD2_k127_4892638_8 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000172 158.0
SHD2_k127_4892638_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000007024 144.0
SHD2_k127_489795_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 9.673e-197 631.0
SHD2_k127_4909333_0 amino acid - - - 1.519e-212 681.0
SHD2_k127_4909333_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 510.0
SHD2_k127_4909333_10 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 334.0
SHD2_k127_4909333_11 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 321.0
SHD2_k127_4909333_12 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 322.0
SHD2_k127_4909333_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001143 268.0
SHD2_k127_4909333_14 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000007687 207.0
SHD2_k127_4909333_15 domain, Protein K20276 - - 0.00000000000000000000000000000000000000000000000002935 204.0
SHD2_k127_4909333_16 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000863 173.0
SHD2_k127_4909333_17 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.00000000000000000000000000000000000002927 156.0
SHD2_k127_4909333_18 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000008892 159.0
SHD2_k127_4909333_19 alpha beta - - - 0.0000000000000000000007892 108.0
SHD2_k127_4909333_2 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 513.0
SHD2_k127_4909333_20 Dodecin K09165 - - 0.000000000000000001179 89.0
SHD2_k127_4909333_21 polysaccharide catabolic process K01179,K01218 - 3.2.1.4,3.2.1.78 0.00000000000000002973 97.0
SHD2_k127_4909333_22 efflux transmembrane transporter activity K12340,K15725 - - 0.0000000000000001864 94.0
SHD2_k127_4909333_23 - - - - 0.0000001449 62.0
SHD2_k127_4909333_3 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 496.0
SHD2_k127_4909333_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 490.0
SHD2_k127_4909333_5 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 477.0
SHD2_k127_4909333_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 459.0
SHD2_k127_4909333_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 425.0
SHD2_k127_4909333_8 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 415.0
SHD2_k127_4909333_9 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 383.0
SHD2_k127_5079538_0 OPT oligopeptide transporter protein - - - 3.365e-203 649.0
SHD2_k127_5079538_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 372.0
SHD2_k127_5079538_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 355.0
SHD2_k127_5079538_3 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000006401 168.0
SHD2_k127_5079538_4 - - - - 0.0000000000000000000004577 101.0
SHD2_k127_5079538_5 PFAM transcriptional regulator domain protein - - - 0.000000000000000000001593 111.0
SHD2_k127_508011_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 1.337e-223 723.0
SHD2_k127_508011_1 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 583.0
SHD2_k127_508011_10 scavenger receptor activity - GO:0003674,GO:0005044,GO:0006810,GO:0006897,GO:0006898,GO:0007155,GO:0007157,GO:0008150,GO:0016192,GO:0022610,GO:0038024,GO:0051179,GO:0051234,GO:0098609,GO:0098657,GO:0098742 - 0.0000106 57.0
SHD2_k127_508011_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 402.0
SHD2_k127_508011_3 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 358.0
SHD2_k127_508011_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 324.0
SHD2_k127_508011_5 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 263.0
SHD2_k127_508011_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000009416 176.0
SHD2_k127_508011_7 metallocarboxypeptidase activity K14054 - - 0.00000000000000000000002572 111.0
SHD2_k127_508011_8 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000004594 103.0
SHD2_k127_508011_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000001483 52.0
SHD2_k127_5156830_0 Parallel beta-helix repeats - - - 0.000000000000000000000000000009346 138.0
SHD2_k127_5156830_1 FlgD Ig-like domain - - - 0.00000000004208 77.0
SHD2_k127_5156830_2 extracellular matrix structural constituent - - - 0.0000005119 62.0
SHD2_k127_5156830_3 alpha beta - - - 0.00005497 57.0
SHD2_k127_5188935_0 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 516.0
SHD2_k127_5188935_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 402.0
SHD2_k127_5188935_10 Helix-turn-helix XRE-family like proteins - - - 0.000000001065 66.0
SHD2_k127_5188935_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000001472 71.0
SHD2_k127_5188935_2 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000035 259.0
SHD2_k127_5188935_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000218 220.0
SHD2_k127_5188935_4 PFAM MazG nucleotide pyrophosphohydrolase K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000392 209.0
SHD2_k127_5188935_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000001226 206.0
SHD2_k127_5188935_6 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000002653 120.0
SHD2_k127_5188935_7 Transcriptional regulator, XRE family with cupin sensor - - - 0.00000000000000000000008069 105.0
SHD2_k127_5188935_8 - - - - 0.000000000000000002238 87.0
SHD2_k127_5188935_9 3D domain protein - - - 0.0000000000003378 79.0
SHD2_k127_5202176_0 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000007156 190.0
SHD2_k127_5202176_1 Cupin domain - - - 0.0005068 49.0
SHD2_k127_5205793_0 cellulose binding - - - 0.0000000000000000000000000000000000000007171 163.0
SHD2_k127_5205793_1 Lamin Tail Domain - - - 0.0000001515 63.0
SHD2_k127_5285796_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1180.0
SHD2_k127_5285796_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.743e-241 771.0
SHD2_k127_5285796_10 tyrosine recombinase XerC K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000008988 220.0
SHD2_k127_5285796_11 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000003514 191.0
SHD2_k127_5285796_12 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000745 196.0
SHD2_k127_5285796_13 ComEC Rec2-related protein K02238 - - 0.000000000000000000000000000000000000000000003082 188.0
SHD2_k127_5285796_14 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000007078 163.0
SHD2_k127_5285796_15 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000001483 139.0
SHD2_k127_5285796_16 TonB-dependent receptor - - - 0.00000000000000000000000000000008961 143.0
SHD2_k127_5285796_17 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.000000000000000000000000000009584 129.0
SHD2_k127_5285796_18 FlgD Ig-like domain K15924 - 3.2.1.136 0.0000000000000000000000382 117.0
SHD2_k127_5285796_19 Peptidase family M23 - - - 0.0000000000000000000005631 112.0
SHD2_k127_5285796_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 583.0
SHD2_k127_5285796_20 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.0000000000000000001958 104.0
SHD2_k127_5285796_21 Trm112p-like protein K09791 - - 0.0000000000000001375 81.0
SHD2_k127_5285796_22 PFAM PEGA domain - - - 0.0000004161 63.0
SHD2_k127_5285796_23 Belongs to the small heat shock protein (HSP20) family - - - 0.000001334 57.0
SHD2_k127_5285796_24 PA14 domain - - - 0.000002985 59.0
SHD2_k127_5285796_25 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.0002032 51.0
SHD2_k127_5285796_26 - - - - 0.0003617 44.0
SHD2_k127_5285796_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 521.0
SHD2_k127_5285796_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 452.0
SHD2_k127_5285796_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 390.0
SHD2_k127_5285796_6 Propeptide_C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 377.0
SHD2_k127_5285796_7 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 354.0
SHD2_k127_5285796_8 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 297.0
SHD2_k127_5285796_9 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000004321 226.0
SHD2_k127_5350019_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1724.0
SHD2_k127_5350019_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 610.0
SHD2_k127_5350019_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003552 239.0
SHD2_k127_5350019_11 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000003351 242.0
SHD2_k127_5350019_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000001923 232.0
SHD2_k127_5350019_13 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000001374 224.0
SHD2_k127_5350019_14 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000005633 217.0
SHD2_k127_5350019_15 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.00000000000000000000000000000000000000000000000003443 200.0
SHD2_k127_5350019_16 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000007655 199.0
SHD2_k127_5350019_17 Capsule biosynthesis CapC K22116 - - 0.0000000000000000000000000000000000808 138.0
SHD2_k127_5350019_18 B3/4 domain - - - 0.00000000000000000000000000000001286 137.0
SHD2_k127_5350019_19 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000003894 135.0
SHD2_k127_5350019_2 Cytochrome b subunit of formate dehydrogenase-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 562.0
SHD2_k127_5350019_20 Tellurite resistance protein TehB - - - 0.00000000000000000000000000002362 129.0
SHD2_k127_5350019_21 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000002748 131.0
SHD2_k127_5350019_22 amine dehydrogenase activity K21449 - - 0.0000000000000000000001922 104.0
SHD2_k127_5350019_23 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000006201 78.0
SHD2_k127_5350019_24 cell adhesion involved in biofilm formation - - - 0.00000000005148 77.0
SHD2_k127_5350019_25 - - - - 0.0000000001176 76.0
SHD2_k127_5350019_26 - - - - 0.00000007899 66.0
SHD2_k127_5350019_27 protein secretion - - - 0.00001333 57.0
SHD2_k127_5350019_28 Pkd domain containing protein - - - 0.00007732 57.0
SHD2_k127_5350019_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 458.0
SHD2_k127_5350019_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 404.0
SHD2_k127_5350019_5 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 297.0
SHD2_k127_5350019_6 Mur ligase middle domain K01932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002342 284.0
SHD2_k127_5350019_7 PFAM MOSC domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008573 257.0
SHD2_k127_5350019_8 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000001396 277.0
SHD2_k127_5350019_9 Proteasomal ATPase OB/ID domain K13527 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001399 261.0
SHD2_k127_5365305_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 1.583e-235 736.0
SHD2_k127_5365305_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 604.0
SHD2_k127_5365305_10 Tetratricopeptide repeat - - - 0.000000001164 72.0
SHD2_k127_5365305_12 extracellular matrix structural constituent - - - 0.0003002 53.0
SHD2_k127_5365305_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family K13687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 425.0
SHD2_k127_5365305_3 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001658 266.0
SHD2_k127_5365305_4 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000003044 173.0
SHD2_k127_5365305_5 PFAM Hemerythrin HHE cation binding domain protein - - - 0.00000000000000000000000000000000000000003215 159.0
SHD2_k127_5365305_6 TonB-dependent receptor - - - 0.000000000000000000000000000000000001339 159.0
SHD2_k127_5365305_7 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000001499 135.0
SHD2_k127_5365305_8 site-specific DNA-methyltransferase (adenine-specific) activity - - - 0.00000000000000008399 93.0
SHD2_k127_5365305_9 hemerythrin HHE cation binding domain - - - 0.000000000000002753 82.0
SHD2_k127_5416401_0 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 374.0
SHD2_k127_5416401_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 355.0
SHD2_k127_5416401_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 302.0
SHD2_k127_5416401_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000001092 220.0
SHD2_k127_5483434_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 476.0
SHD2_k127_5483434_1 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 330.0
SHD2_k127_5486514_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 304.0
SHD2_k127_5486514_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000008954 245.0
SHD2_k127_5486514_10 Methyltransferase domain - - - 0.00000000005944 73.0
SHD2_k127_5486514_11 Polysaccharide biosynthesis protein - - - 0.000213 55.0
SHD2_k127_5486514_2 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000003723 202.0
SHD2_k127_5486514_3 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000001801 154.0
SHD2_k127_5486514_4 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000003333 158.0
SHD2_k127_5486514_5 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000006479 132.0
SHD2_k127_5486514_6 Heparinase II/III-like protein K19051 GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510 4.2.2.7,4.2.2.8 0.0000000000000000000000000009849 131.0
SHD2_k127_5486514_7 Bacterial capsule synthesis protein PGA_cap - - - 0.000000000000000000000000001864 125.0
SHD2_k127_5486514_8 Polysaccharide deacetylase - - - 0.000000000000000000000001631 115.0
SHD2_k127_5486514_9 Polysaccharide deacetylase - - - 0.0000000000000000000002375 110.0
SHD2_k127_5528180_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 547.0
SHD2_k127_5528180_1 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.0000000000000000000000000000000000000000000000000000000000000001899 230.0
SHD2_k127_5528180_2 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 - - 0.00000000000003035 84.0
SHD2_k127_5528180_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000002356 70.0
SHD2_k127_5528180_4 peptidase activity, acting on L-amino acid peptides - - - 0.00000000227 69.0
SHD2_k127_5528180_5 - - - - 0.0000003963 57.0
SHD2_k127_5533037_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 2.058e-260 819.0
SHD2_k127_5533037_1 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 4.169e-242 756.0
SHD2_k127_5533037_10 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0003914 53.0
SHD2_k127_5533037_2 Oxidoreductase molybdopterin binding domain - - - 3.764e-197 625.0
SHD2_k127_5533037_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 557.0
SHD2_k127_5533037_4 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 520.0
SHD2_k127_5533037_5 hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 348.0
SHD2_k127_5533037_6 glucosamine-6-phosphate deaminase activity K00851,K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000005777 244.0
SHD2_k127_5533037_7 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000002815 166.0
SHD2_k127_5533037_8 cellulose binding - - - 0.0000000008705 71.0
SHD2_k127_5570935_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 612.0
SHD2_k127_5570935_1 RNA recognition motif - - - 0.00000000000000000000000000000000004486 139.0
SHD2_k127_5570935_2 Psort location Cytoplasmic, score - - - 0.0000000000000000000001197 102.0
SHD2_k127_5570935_3 Protein conserved in bacteria - - - 0.000000000001128 78.0
SHD2_k127_5570935_4 heat shock protein binding - - - 0.00001788 55.0
SHD2_k127_5574040_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 574.0
SHD2_k127_5574040_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 500.0
SHD2_k127_5574040_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000001125 66.0
SHD2_k127_5574040_11 Domain of unknown function (DUF4394) - - - 0.000002676 61.0
SHD2_k127_5574040_12 Protein conserved in bacteria K09800 - - 0.0005097 54.0
SHD2_k127_5574040_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 421.0
SHD2_k127_5574040_3 Participates in initiation and elongation during chromosome replication - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 430.0
SHD2_k127_5574040_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 381.0
SHD2_k127_5574040_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 295.0
SHD2_k127_5574040_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000006848 178.0
SHD2_k127_5574040_7 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000784 167.0
SHD2_k127_5574040_8 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000002556 167.0
SHD2_k127_5574040_9 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000004864 153.0
SHD2_k127_5595595_0 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 361.0
SHD2_k127_5595595_1 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000002796 103.0
SHD2_k127_5595595_2 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.0000000000000000001033 98.0
SHD2_k127_5595595_3 protein secretion K09800 - - 0.00000000002427 79.0
SHD2_k127_5595595_4 Metallo-peptidase family M12B Reprolysin-like - - - 0.000004268 62.0
SHD2_k127_561031_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000222 262.0
SHD2_k127_561031_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000001998 229.0
SHD2_k127_561031_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000009656 166.0
SHD2_k127_5618265_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000001596 125.0
SHD2_k127_5618265_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000006748 96.0
SHD2_k127_5618265_2 cellulase activity - - - 0.0000000002756 68.0
SHD2_k127_5620570_0 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 302.0
SHD2_k127_5620570_1 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000000000009163 238.0
SHD2_k127_5620570_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000001676 83.0
SHD2_k127_5645634_0 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 357.0
SHD2_k127_5645634_1 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000003137 201.0
SHD2_k127_5645634_2 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000169 195.0
SHD2_k127_5645634_3 Polysulphide reductase K00185 - - 0.0000000000000000000000000000000002704 134.0
SHD2_k127_5657801_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002834 266.0
SHD2_k127_5657801_1 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000008385 156.0
SHD2_k127_5657801_2 Parallel beta-helix repeats - - - 0.00000000000000000000009306 107.0
SHD2_k127_5663904_0 ATPase BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 459.0
SHD2_k127_5663904_1 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 403.0
SHD2_k127_5663904_2 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006635 279.0
SHD2_k127_5663904_3 Calcium ion binding - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.000000000007039 79.0
SHD2_k127_5663904_4 Helix-turn-helix domain K21903 - - 0.000000002217 63.0
SHD2_k127_5669597_0 RNA ligase activity K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 568.0
SHD2_k127_5669597_1 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 484.0
SHD2_k127_5669597_10 Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.00000000000000000000001772 111.0
SHD2_k127_5669597_11 RNA methyltransferase TrmH family K00556 - 2.1.1.34 0.00000000000000000002517 107.0
SHD2_k127_5669597_12 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000829 96.0
SHD2_k127_5669597_13 domain protein K14194 - - 0.00004431 57.0
SHD2_k127_5669597_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 361.0
SHD2_k127_5669597_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000001384 243.0
SHD2_k127_5669597_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000001099 187.0
SHD2_k127_5669597_5 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000009058 178.0
SHD2_k127_5669597_6 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000002284 171.0
SHD2_k127_5669597_7 Eco57I restriction-modification methylase - - - 0.0000000000000000000000000000000000000000001142 184.0
SHD2_k127_5669597_8 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000006743 163.0
SHD2_k127_5669597_9 amino acid activation for nonribosomal peptide biosynthetic process K01113 - 3.1.3.1 0.0000000000000000000000000000000008398 148.0
SHD2_k127_5753631_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 576.0
SHD2_k127_5753631_1 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 445.0
SHD2_k127_5753631_10 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000203 250.0
SHD2_k127_5753631_11 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000003144 226.0
SHD2_k127_5753631_12 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000006123 192.0
SHD2_k127_5753631_13 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000006475 161.0
SHD2_k127_5753631_14 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000002433 172.0
SHD2_k127_5753631_15 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000001331 153.0
SHD2_k127_5753631_16 PFAM glycosyl transferase family 9 K02843 - - 0.000000000000000000000000000000000001607 151.0
SHD2_k127_5753631_17 Mg2 transporter-C family protein K07507 - - 0.000000000000000000000000001786 128.0
SHD2_k127_5753631_18 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000006354 105.0
SHD2_k127_5753631_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 426.0
SHD2_k127_5753631_20 - - - - 0.000000000000000000003367 99.0
SHD2_k127_5753631_21 MerR family transcriptional regulator - - - 0.00000000000000000246 98.0
SHD2_k127_5753631_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 391.0
SHD2_k127_5753631_4 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 367.0
SHD2_k127_5753631_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 368.0
SHD2_k127_5753631_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 335.0
SHD2_k127_5753631_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 306.0
SHD2_k127_5753631_8 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001471 283.0
SHD2_k127_5753631_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000001222 268.0
SHD2_k127_5764742_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 3.129e-301 943.0
SHD2_k127_5764742_1 iron-nicotianamine transmembrane transporter activity - - - 2.79e-295 931.0
SHD2_k127_5764742_10 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 317.0
SHD2_k127_5764742_11 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 320.0
SHD2_k127_5764742_12 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 304.0
SHD2_k127_5764742_13 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 310.0
SHD2_k127_5764742_14 Bacterial sugar transferase K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002207 295.0
SHD2_k127_5764742_15 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001993 310.0
SHD2_k127_5764742_16 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000003924 274.0
SHD2_k127_5764742_17 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004459 272.0
SHD2_k127_5764742_18 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000002611 240.0
SHD2_k127_5764742_19 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000309 247.0
SHD2_k127_5764742_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 7.251e-256 802.0
SHD2_k127_5764742_20 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001796 254.0
SHD2_k127_5764742_21 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004291 244.0
SHD2_k127_5764742_22 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000012 228.0
SHD2_k127_5764742_23 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000003465 216.0
SHD2_k127_5764742_24 serine-type endopeptidase activity K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000003214 194.0
SHD2_k127_5764742_25 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000001596 203.0
SHD2_k127_5764742_26 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000001408 188.0
SHD2_k127_5764742_27 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000005159 183.0
SHD2_k127_5764742_28 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000001198 183.0
SHD2_k127_5764742_29 Prephenate dehydrogenase K00210 - 1.3.1.12 0.0000000000000000000000000000000000000000009416 176.0
SHD2_k127_5764742_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.415e-248 781.0
SHD2_k127_5764742_30 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.0000000000000000000000000000000000002862 152.0
SHD2_k127_5764742_31 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000382 148.0
SHD2_k127_5764742_32 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000005068 133.0
SHD2_k127_5764742_33 PFAM response regulator receiver - - - 0.000000000000000000000000002748 116.0
SHD2_k127_5764742_34 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000005142 108.0
SHD2_k127_5764742_35 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.0000000000000000006405 91.0
SHD2_k127_5764742_36 protein conserved in bacteria (DUF2087) - - - 0.00000000000000000459 91.0
SHD2_k127_5764742_37 domain, Protein - - - 0.00000000004111 76.0
SHD2_k127_5764742_38 - - - - 0.00000009954 62.0
SHD2_k127_5764742_4 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.556e-208 658.0
SHD2_k127_5764742_40 DNA binding domain, excisionase family - - - 0.000135 51.0
SHD2_k127_5764742_41 - - - - 0.0008134 46.0
SHD2_k127_5764742_43 PFAM Glycosyl transferase, group 1 - - - 0.0009704 51.0
SHD2_k127_5764742_5 Aminotransferase class-V K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 431.0
SHD2_k127_5764742_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 407.0
SHD2_k127_5764742_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 380.0
SHD2_k127_5764742_8 Phenylalanyl-tRNA synthetase beta K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 375.0
SHD2_k127_5764742_9 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 344.0
SHD2_k127_5790715_0 NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein - - - 2.48e-261 824.0
SHD2_k127_5790715_1 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 651.0
SHD2_k127_5790715_10 Involved in the tonB-independent uptake of proteins - - - 0.0000007434 63.0
SHD2_k127_5790715_11 TIGRFAM TOMM propeptide domain - - - 0.00001508 53.0
SHD2_k127_5790715_12 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000258 54.0
SHD2_k127_5790715_14 Transcription initiation factor TFIID complex subunit TAF8 - - - 0.0009153 44.0
SHD2_k127_5790715_2 Lanthionine synthetase C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 497.0
SHD2_k127_5790715_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002829 278.0
SHD2_k127_5790715_4 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000003636 228.0
SHD2_k127_5790715_5 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.00000000000000000000000000000000000000000000000000000002118 222.0
SHD2_k127_5790715_6 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000001379 174.0
SHD2_k127_5790715_7 HlyD family secretion protein K02022 - - 0.0000000000000000000000003627 119.0
SHD2_k127_5790715_8 Outer membrane efflux protein - - - 0.000000000000000000002481 109.0
SHD2_k127_5790715_9 Outer membrane efflux protein - - - 0.000000000000000004475 99.0
SHD2_k127_5820862_0 Beta-ketoacyl synthase - - - 5.117e-318 1001.0
SHD2_k127_5820862_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 425.0
SHD2_k127_5820862_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 288.0
SHD2_k127_5820862_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000722 302.0
SHD2_k127_5820862_4 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007435 263.0
SHD2_k127_5820862_5 Protein of unknown function (DUF1579) - - - 0.000000000000000005012 92.0
SHD2_k127_5820862_6 Cupin 2, conserved barrel domain protein - - - 0.0000009344 54.0
SHD2_k127_5882155_0 LVIVD repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 350.0
SHD2_k127_5882155_1 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000001682 259.0
SHD2_k127_5882155_2 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000001568 181.0
SHD2_k127_5882155_3 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000004179 143.0
SHD2_k127_5882155_4 endonuclease activity K07451 - - 0.00000000001618 68.0
SHD2_k127_5882674_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003524 275.0
SHD2_k127_5908450_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.717e-279 874.0
SHD2_k127_5908450_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 5.662e-195 628.0
SHD2_k127_5908450_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000213 213.0
SHD2_k127_5908450_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000003258 203.0
SHD2_k127_5908450_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000008817 81.0
SHD2_k127_5922537_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.274e-262 826.0
SHD2_k127_5922537_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.507e-205 663.0
SHD2_k127_5922537_10 Protein of unknown function (DUF503) K09764 - - 0.0000000000004052 74.0
SHD2_k127_5922537_2 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 392.0
SHD2_k127_5922537_3 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 340.0
SHD2_k127_5922537_4 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000001971 228.0
SHD2_k127_5922537_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177,K03483 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000004481 215.0
SHD2_k127_5922537_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000001648 206.0
SHD2_k127_5922537_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000006658 121.0
SHD2_k127_5922537_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000002595 111.0
SHD2_k127_5922537_9 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000005622 101.0
SHD2_k127_5985204_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 9.8e-236 741.0
SHD2_k127_5985204_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.991e-217 687.0
SHD2_k127_5985204_10 Acetyl-CoA carboxylase, central region - - - 0.000000000634 72.0
SHD2_k127_5985204_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 505.0
SHD2_k127_5985204_3 PFAM Glycosyl transferases group 1 K16703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 375.0
SHD2_k127_5985204_4 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 312.0
SHD2_k127_5985204_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 296.0
SHD2_k127_5985204_6 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 288.0
SHD2_k127_5985204_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000001463 209.0
SHD2_k127_5985204_8 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000007115 102.0
SHD2_k127_5985204_9 PFAM thioesterase superfamily - - - 0.00000000000000000000356 109.0
SHD2_k127_6091551_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.979e-209 664.0
SHD2_k127_6091551_1 PFAM 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 1.54e-199 633.0
SHD2_k127_6091551_10 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000007635 132.0
SHD2_k127_6091551_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.0000000001465 71.0
SHD2_k127_6091551_12 extracellular matrix structural constituent - - - 0.0000002419 61.0
SHD2_k127_6091551_13 Belongs to the glycosyl hydrolase 13 family - - - 0.00000102 63.0
SHD2_k127_6091551_14 cellulose binding K00505 - 1.14.18.1 0.000007046 59.0
SHD2_k127_6091551_2 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 475.0
SHD2_k127_6091551_3 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 420.0
SHD2_k127_6091551_4 PFAM Xanthine uracil vitamin C permease K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 394.0
SHD2_k127_6091551_5 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 325.0
SHD2_k127_6091551_6 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 331.0
SHD2_k127_6091551_7 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000008377 172.0
SHD2_k127_6091551_8 SPTR Peptidase S8 and S53 subtilisin kexin sedolisin K01113,K14645,K17713 - 3.1.3.1 0.00000000000000000000000000000000000000005093 170.0
SHD2_k127_6091551_9 - - - - 0.00000000000000000000000000000002583 141.0
SHD2_k127_6091776_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 1.521e-311 974.0
SHD2_k127_6091776_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 327.0
SHD2_k127_6091776_2 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000001652 164.0
SHD2_k127_6131812_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1184.0
SHD2_k127_6131812_1 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 4.124e-226 706.0
SHD2_k127_6131812_10 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000002888 147.0
SHD2_k127_6131812_11 Cysteine-type peptidase activity. It is involved in the biological process described with proteolysis K01365,K01368,K01371 GO:0000003,GO:0000323,GO:0002376,GO:0003674,GO:0003824,GO:0004175,GO:0004177,GO:0004197,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0006508,GO:0006807,GO:0006915,GO:0006919,GO:0006955,GO:0008047,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0008238,GO:0008656,GO:0009056,GO:0009057,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0016504,GO:0016505,GO:0016787,GO:0019222,GO:0019538,GO:0023051,GO:0023056,GO:0030162,GO:0030163,GO:0030234,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0032501,GO:0032504,GO:0042981,GO:0043028,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043280,GO:0043281,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051603,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0098772,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:2000116,GO:2001056,GO:2001233,GO:2001235 3.4.22.15,3.4.22.27,3.4.22.38 0.00000000000000000000000000000002642 140.0
SHD2_k127_6131812_12 ThiS family K03636 - - 0.00000000000000000000001296 112.0
SHD2_k127_6131812_13 CARDB - - - 0.0000000000000000005402 103.0
SHD2_k127_6131812_14 Parallel beta-helix repeats - - - 0.00000000000000003676 94.0
SHD2_k127_6131812_15 Cation transport ATPase K17686 - 3.6.3.54 0.00000000163 66.0
SHD2_k127_6131812_2 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 3.119e-212 689.0
SHD2_k127_6131812_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 1.636e-208 664.0
SHD2_k127_6131812_4 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 599.0
SHD2_k127_6131812_5 response regulator K02481,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 452.0
SHD2_k127_6131812_6 metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 355.0
SHD2_k127_6131812_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 291.0
SHD2_k127_6131812_8 Domains HisKA, HATPase_c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001228 270.0
SHD2_k127_6131812_9 ferredoxin iron-sulfur binding - - - 0.0000000000000000000000000000000000000001014 159.0
SHD2_k127_614647_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000003208 216.0
SHD2_k127_614647_1 PFAM NUDIX domain - - - 0.00000000000000000000000000001364 136.0
SHD2_k127_614647_2 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000003198 104.0
SHD2_k127_614647_3 Spore coat protein CotH K20276 - - 0.00000001077 69.0
SHD2_k127_6165527_0 CHAD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009742 278.0
SHD2_k127_6165527_1 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000000007574 132.0
SHD2_k127_6188763_0 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 1.067e-196 632.0
SHD2_k127_6188763_1 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000008026 108.0
SHD2_k127_6188763_2 Sulfotransferase family - - - 0.00001439 57.0
SHD2_k127_6194041_0 heat shock protein binding - - - 1.435e-233 747.0
SHD2_k127_6194041_1 phosphorelay sensor kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 567.0
SHD2_k127_6205467_0 SMART Integrin alpha beta-propellor repeat protein - - - 7.116e-216 724.0
SHD2_k127_6205467_1 chelatase, subunit ChlI K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 482.0
SHD2_k127_6205467_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 379.0
SHD2_k127_6205467_3 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008046 300.0
SHD2_k127_6205467_4 - - - - 0.00000000000000000000000007758 119.0
SHD2_k127_6205467_5 sequence-specific DNA binding K18830 - - 0.00000001397 59.0
SHD2_k127_6205467_6 - - - - 0.00002471 58.0
SHD2_k127_6205467_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0002148 51.0
SHD2_k127_621312_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.56e-231 730.0
SHD2_k127_621312_1 PFAM tRNA synthetase class II (D K and N), nucleic acid binding OB-fold tRNA helicase-type K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 572.0
SHD2_k127_621312_10 Diguanylate cyclase - - - 0.00000000000000000000000000022 118.0
SHD2_k127_621312_11 Tetratricopeptide repeat - - - 0.00000000001496 78.0
SHD2_k127_621312_12 Domain of unknown function (DUF4388) - - - 0.0000000722 64.0
SHD2_k127_621312_13 Periplasmic component of the Tol biopolymer transport system - - - 0.00001884 48.0
SHD2_k127_621312_14 Cytochrome c554 and c-prime - - - 0.0007981 52.0
SHD2_k127_621312_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 535.0
SHD2_k127_621312_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 315.0
SHD2_k127_621312_4 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 322.0
SHD2_k127_621312_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 314.0
SHD2_k127_621312_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000005344 242.0
SHD2_k127_621312_7 D,D-heptose 1,7-bisphosphate phosphatase K03273,K15669 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 2.7.7.71,3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000003956 181.0
SHD2_k127_621312_8 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000007389 182.0
SHD2_k127_621312_9 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000004691 132.0
SHD2_k127_6224229_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.247e-308 969.0
SHD2_k127_6224229_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 3.128e-269 843.0
SHD2_k127_6224229_10 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000002227 141.0
SHD2_k127_6224229_11 translation initiation factor activity - - - 0.0000000000000000000001502 111.0
SHD2_k127_6224229_12 repeat protein - - - 0.000003939 56.0
SHD2_k127_6224229_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 480.0
SHD2_k127_6224229_3 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 427.0
SHD2_k127_6224229_4 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 408.0
SHD2_k127_6224229_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 314.0
SHD2_k127_6224229_6 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001146 283.0
SHD2_k127_6224229_7 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 - 1.4.3.16,2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000649 237.0
SHD2_k127_6224229_8 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000003816 196.0
SHD2_k127_6224229_9 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000005918 183.0
SHD2_k127_6257234_0 Thymidylate synthase complementing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 306.0
SHD2_k127_6257234_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000002866 267.0
SHD2_k127_6257234_2 Belongs to the peptidase S11 family K01286,K07258 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000005572 220.0
SHD2_k127_6257234_3 Trypsin-like serine protease K01337 - 3.4.21.50 0.000000000000000000000000000001249 140.0
SHD2_k127_6257234_4 Subtilase family - - - 0.00000000001777 78.0
SHD2_k127_6257234_5 Subtilase family - - - 0.000000001136 72.0
SHD2_k127_6316316_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 376.0
SHD2_k127_6316316_1 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000002486 246.0
SHD2_k127_6316316_2 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000002968 188.0
SHD2_k127_6316316_3 Lamin Tail Domain - - - 0.00000000000000000000000001194 126.0
SHD2_k127_6353926_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 368.0
SHD2_k127_6353926_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 362.0
SHD2_k127_6353926_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000212 274.0
SHD2_k127_6353926_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000006312 131.0
SHD2_k127_6353926_4 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000002504 83.0
SHD2_k127_6353926_5 Glycosyl transferases group 1 - - - 0.0000002068 63.0
SHD2_k127_6356239_0 Seven times multi-haem cytochrome CxxCH K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 3.695e-214 671.0
SHD2_k127_6356239_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 4.529e-197 639.0
SHD2_k127_6356239_10 PFAM response regulator receiver K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001104 254.0
SHD2_k127_6356239_11 Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009893,GO:0009987,GO:0019216,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045828,GO:0045834,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:0080090,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003814 257.0
SHD2_k127_6356239_12 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001677 258.0
SHD2_k127_6356239_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000005148 248.0
SHD2_k127_6356239_14 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000005606 177.0
SHD2_k127_6356239_15 domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000007004 181.0
SHD2_k127_6356239_16 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000001239 182.0
SHD2_k127_6356239_17 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.00000000000000000000000000000000000000000001229 171.0
SHD2_k127_6356239_18 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000005919 126.0
SHD2_k127_6356239_19 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000003997 123.0
SHD2_k127_6356239_2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 610.0
SHD2_k127_6356239_20 iron-sulfur cluster assembly - - - 0.000000000000000005258 87.0
SHD2_k127_6356239_21 Glutaredoxin - - - 0.00000000000000491 79.0
SHD2_k127_6356239_22 peroxiredoxin activity - - - 0.00000000002906 76.0
SHD2_k127_6356239_23 - - - - 0.0004205 51.0
SHD2_k127_6356239_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 421.0
SHD2_k127_6356239_4 FIST C domain K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 410.0
SHD2_k127_6356239_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 387.0
SHD2_k127_6356239_6 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 346.0
SHD2_k127_6356239_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002027 291.0
SHD2_k127_6356239_8 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000733 285.0
SHD2_k127_6356239_9 PHP domain protein K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006802 266.0
SHD2_k127_6364881_0 peptidase activity, acting on L-amino acid peptides K20276 - - 0.0000000000000000000000000000000008475 139.0
SHD2_k127_6364881_1 extracellular matrix structural constituent - - - 0.00000000158 71.0
SHD2_k127_6372237_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 582.0
SHD2_k127_6372237_1 PFAM glycosyl transferase family 9 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 311.0
SHD2_k127_6372237_11 Integrase - - - 0.0004827 44.0
SHD2_k127_6372237_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000949 279.0
SHD2_k127_6372237_3 agmatine deiminase activity K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000002656 239.0
SHD2_k127_6372237_4 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000001745 198.0
SHD2_k127_6372237_5 Clp amino terminal domain, pathogenicity island component K03696 - - 0.0000000000000000005795 92.0
SHD2_k127_6372237_6 amine dehydrogenase activity - - - 0.0000000003322 72.0
SHD2_k127_6372237_7 - - - - 0.0000000006271 72.0
SHD2_k127_6372237_8 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000001344 62.0
SHD2_k127_6372237_9 Integrase - - - 0.000004066 54.0
SHD2_k127_6393273_0 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 9.811e-208 666.0
SHD2_k127_6393273_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 473.0
SHD2_k127_6393273_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 409.0
SHD2_k127_6393273_3 Aminopeptidase K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 338.0
SHD2_k127_6393273_4 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000002615 135.0
SHD2_k127_6393273_5 ATP synthesis coupled electron transport K00340,K05576 - 1.6.5.3 0.0000000000000000000000001306 118.0
SHD2_k127_6393273_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.0000000005444 63.0
SHD2_k127_6408178_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 401.0
SHD2_k127_6408178_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000007453 207.0
SHD2_k127_6408178_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000001691 179.0
SHD2_k127_6408178_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000427 100.0
SHD2_k127_6411694_0 Amp-dependent synthetase and ligase K00797,K01897 - 2.5.1.16,6.2.1.3 3.151e-308 1000.0
SHD2_k127_6411694_1 Citrate lyase, alpha subunit (CitF) K01643 - 2.8.3.10 2.217e-252 807.0
SHD2_k127_6411694_10 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 316.0
SHD2_k127_6411694_11 Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 285.0
SHD2_k127_6411694_12 PFAM response regulator receiver ATP-binding region, ATPase-like histidine kinase A-like Hpt PAS fold-3 PAS fold-4 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000001072 254.0
SHD2_k127_6411694_13 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000001054 163.0
SHD2_k127_6411694_14 Bacterial pre-peptidase C-terminal domain - - - 0.000000000000000000000000000000000000000002672 173.0
SHD2_k127_6411694_15 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000008629 149.0
SHD2_k127_6411694_16 domain, Protein K20276 - - 0.0000000000000000000000000000000000005982 156.0
SHD2_k127_6411694_17 AI-2E family transporter - - - 0.000000000000000000000000000000000009201 151.0
SHD2_k127_6411694_18 Exonuclease - - - 0.000000000000000000000000000000001052 137.0
SHD2_k127_6411694_19 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000008603 133.0
SHD2_k127_6411694_2 Carbon starvation protein K06200 - - 3.858e-215 728.0
SHD2_k127_6411694_20 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000006718 115.0
SHD2_k127_6411694_21 - - - - 0.000000000000000000004349 95.0
SHD2_k127_6411694_22 Iron-sulfur cluster-binding domain - - - 0.000000000000000003126 96.0
SHD2_k127_6411694_23 Glutathione peroxidase - - - 0.000000000000001413 80.0
SHD2_k127_6411694_24 PFAM Prokaryotic dksA traR C4-type zinc finger - - - 0.00000000000001466 81.0
SHD2_k127_6411694_25 cellulose binding K00505 - 1.14.18.1 0.0000000000001244 85.0
SHD2_k127_6411694_26 Glycosyltransferase family 87 - - - 0.0000000000006942 82.0
SHD2_k127_6411694_27 Bacterial Ig-like domain (group 1) - - - 0.000000005534 68.0
SHD2_k127_6411694_28 subunit of a heme lyase K02200 - - 0.00000001839 64.0
SHD2_k127_6411694_29 cellulose binding - - - 0.0000005311 61.0
SHD2_k127_6411694_3 3-isopropylmalate dehydrogenase activity K00052 - 1.1.1.85 5.824e-205 642.0
SHD2_k127_6411694_30 Glutathione peroxidase - - - 0.0009541 50.0
SHD2_k127_6411694_4 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 618.0
SHD2_k127_6411694_5 HpcH/HpaI aldolase/citrate lyase family K01644,K01646,K18292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008815,GO:0009346,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0032991,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 473.0
SHD2_k127_6411694_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 437.0
SHD2_k127_6411694_7 citrate synthase K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 400.0
SHD2_k127_6411694_8 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 371.0
SHD2_k127_6411694_9 Subtilase family K13276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 332.0
SHD2_k127_6421006_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.362e-214 700.0
SHD2_k127_6421006_1 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 464.0
SHD2_k127_6421006_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000002052 112.0
SHD2_k127_6421006_11 - - - - 0.00000000000000000447 100.0
SHD2_k127_6421006_12 outer membrane assembly lipoprotein YfiO K05807 - - 0.0000000000000006288 89.0
SHD2_k127_6421006_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07671 GO:0000287,GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043167,GO:0043169,GO:0044110,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051704,GO:0071944 - 0.000000000000004696 84.0
SHD2_k127_6421006_14 Preprotein translocase, subunit SecG K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000003084 75.0
SHD2_k127_6421006_15 Peptidase M56 - - - 0.0000000000003966 82.0
SHD2_k127_6421006_16 formate dehydrogenase K00127,K03620 - - 0.000000000000637 81.0
SHD2_k127_6421006_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 388.0
SHD2_k127_6421006_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 330.0
SHD2_k127_6421006_4 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 298.0
SHD2_k127_6421006_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003478 279.0
SHD2_k127_6421006_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000294 243.0
SHD2_k127_6421006_7 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000005815 205.0
SHD2_k127_6421006_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000003295 143.0
SHD2_k127_6421006_9 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000002297 143.0
SHD2_k127_6424739_0 Predicted ATPase of the ABC class - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 389.0
SHD2_k127_6424739_1 Zinc metalloprotease (Elastase) K20274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000184 292.0
SHD2_k127_6424739_2 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000006082 249.0
SHD2_k127_6424739_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000009831 158.0
SHD2_k127_6424739_4 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000002278 148.0
SHD2_k127_6424739_5 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000009911 154.0
SHD2_k127_6424739_6 Outer membrane lipoprotein - - - 0.0000000000000000000000005138 115.0
SHD2_k127_6424739_7 MFS_1 like family - - - 0.00000000008317 74.0
SHD2_k127_6424739_8 TonB C terminal K03832 - - 0.0007475 51.0
SHD2_k127_6451223_0 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 466.0
SHD2_k127_6451223_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000005141 217.0
SHD2_k127_6451223_2 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000003951 188.0
SHD2_k127_6451223_5 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000002051 92.0
SHD2_k127_6451223_6 Protein of unknown function (DUF2723) - - - 0.00000000000000005804 94.0
SHD2_k127_6451223_7 dehydrogenase reductase - - - 0.0003328 44.0
SHD2_k127_6451223_8 Anti-sigma-K factor rskA - - - 0.000619 50.0
SHD2_k127_6461464_0 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004499 289.0
SHD2_k127_6461464_1 lyase activity K01387,K03301 - 3.4.24.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005735 278.0
SHD2_k127_6461464_10 bacterial (prokaryotic) histone like domain - - - 0.000000000000000001048 89.0
SHD2_k127_6461464_11 Evidence 5 No homology to any previously reported sequences K01083,K01729,K12287 - 3.1.3.8,4.2.2.3 0.000000000000000001673 100.0
SHD2_k127_6461464_12 LVIVD repeat K01179 - 3.2.1.4 0.0000000002536 76.0
SHD2_k127_6461464_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000004755 220.0
SHD2_k127_6461464_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000002046 155.0
SHD2_k127_6461464_4 Yqey-like protein K09117 - - 0.0000000000000000000000000000003266 128.0
SHD2_k127_6461464_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000004802 133.0
SHD2_k127_6461464_6 Histidine kinase - - - 0.000000000000000000000002026 106.0
SHD2_k127_6461464_7 auxin efflux carrier family protein K07088 - - 0.0000000000000000000005026 106.0
SHD2_k127_6461464_8 Glycosyl transferases group 1 K00786 - - 0.000000000000000000002084 100.0
SHD2_k127_6461464_9 PFAM nucleic acid binding, OB-fold, tRNA K02390 - - 0.000000000000000000006323 108.0
SHD2_k127_6464491_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001254 283.0
SHD2_k127_6464491_1 Belongs to the peptidase S8 family K08651,K14743 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000005147 218.0
SHD2_k127_6464491_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000002265 113.0
SHD2_k127_6464491_3 cellulose binding - - - 0.000000005736 60.0
SHD2_k127_6481063_0 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 477.0
SHD2_k127_6481063_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 470.0
SHD2_k127_6481063_10 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000001593 176.0
SHD2_k127_6481063_11 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000002821 182.0
SHD2_k127_6481063_12 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000001567 160.0
SHD2_k127_6481063_13 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000002012 166.0
SHD2_k127_6481063_14 Fibronectin-binding protein A N-terminus (FbpA) K01153,K15524 - 3.1.21.3,3.2.1.170 0.0000000000000000000000000002068 132.0
SHD2_k127_6481063_15 - - - - 0.000000000686 66.0
SHD2_k127_6481063_16 - - - - 0.00001857 47.0
SHD2_k127_6481063_2 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 455.0
SHD2_k127_6481063_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 446.0
SHD2_k127_6481063_4 Selenocysteine-specific translation elongation factor K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 404.0
SHD2_k127_6481063_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 328.0
SHD2_k127_6481063_6 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000001286 226.0
SHD2_k127_6481063_7 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000001706 216.0
SHD2_k127_6481063_8 stage II sporulation K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000005272 206.0
SHD2_k127_6481063_9 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000001326 176.0
SHD2_k127_6495949_0 phosphorelay sensor kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 560.0
SHD2_k127_6495949_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000003504 246.0
SHD2_k127_6495949_2 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000000004588 199.0
SHD2_k127_6496859_0 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 602.0
SHD2_k127_6496859_1 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 562.0
SHD2_k127_6496859_10 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000004123 220.0
SHD2_k127_6496859_11 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000001473 222.0
SHD2_k127_6496859_12 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.0000000000000000000000000000001943 144.0
SHD2_k127_6496859_13 - - - - 0.000000000000000000000000000002412 130.0
SHD2_k127_6496859_14 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000236 95.0
SHD2_k127_6496859_15 - - - - 0.0000000000000005308 88.0
SHD2_k127_6496859_16 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000254 88.0
SHD2_k127_6496859_17 extracellular matrix structural constituent - - - 0.000000000001002 81.0
SHD2_k127_6496859_18 Domain of unknown function (DUF4082) - - - 0.00000000003847 76.0
SHD2_k127_6496859_19 cellulose binding - - - 0.00000000009865 73.0
SHD2_k127_6496859_2 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 530.0
SHD2_k127_6496859_20 Evidence 5 No homology to any previously reported sequences - - - 0.00000003382 68.0
SHD2_k127_6496859_21 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.00006977 57.0
SHD2_k127_6496859_3 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 482.0
SHD2_k127_6496859_4 aminoacyl-histidine dipeptidase K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 413.0
SHD2_k127_6496859_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 342.0
SHD2_k127_6496859_6 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 316.0
SHD2_k127_6496859_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001007 294.0
SHD2_k127_6496859_8 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005975 299.0
SHD2_k127_6496859_9 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000001058 261.0
SHD2_k127_6505934_0 FlgD Ig-like domain - - - 0.0000000000000000000000000000000000000000000000000003834 210.0
SHD2_k127_6505934_1 Cytochrome c - - - 0.0000000000000002628 91.0
SHD2_k127_6505934_2 PFAM Outer membrane efflux protein - - - 0.0000000001218 70.0
SHD2_k127_6505934_4 Predicted membrane protein (DUF2231) - - - 0.000006992 58.0
SHD2_k127_6507929_0 NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein - - - 3.972e-261 824.0
SHD2_k127_6507929_1 Peptidase C39 family K06147 - - 1.42e-199 672.0
SHD2_k127_6507929_10 efflux transmembrane transporter activity - - - 0.0000004272 63.0
SHD2_k127_6507929_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 514.0
SHD2_k127_6507929_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000001284 239.0
SHD2_k127_6507929_4 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000005453 224.0
SHD2_k127_6507929_5 PFAM Protein phosphatase 2C K20074 - 3.1.3.16 0.00000000000000000000000000000000000000006878 162.0
SHD2_k127_6507929_6 Parallel beta-helix repeats - - - 0.0000000000000000000000000000001324 143.0
SHD2_k127_6507929_7 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000001759 128.0
SHD2_k127_6507929_8 Outer membrane efflux protein - - - 0.00000000000000000000003836 110.0
SHD2_k127_6507929_9 chlorophyll binding - - - 0.000000000006388 79.0
SHD2_k127_6560054_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 8.574e-194 649.0
SHD2_k127_6560054_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 522.0
SHD2_k127_6560054_10 PFAM Mandelate racemase muconate lactonizing K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000004307 194.0
SHD2_k127_6560054_11 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000001517 141.0
SHD2_k127_6560054_12 belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000001002 124.0
SHD2_k127_6560054_13 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000852 124.0
SHD2_k127_6560054_14 Oxidoreductase FAD-binding domain K18225 - - 0.0000000000000000000000001596 119.0
SHD2_k127_6560054_15 PFAM glycine cleavage H-protein - - - 0.00000000000000000000005937 108.0
SHD2_k127_6560054_16 Adenine glycosylase K03574,K03575 - 3.6.1.55 0.0000000000000000000002007 110.0
SHD2_k127_6560054_17 Peptidylprolyl isomerase K01802,K03769 - 5.2.1.8 0.0000000000000000001107 104.0
SHD2_k127_6560054_18 phosphorelay signal transduction system K02437 - - 0.0000000000000001729 91.0
SHD2_k127_6560054_19 Lipoprotein - - - 0.000000000000001145 84.0
SHD2_k127_6560054_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 396.0
SHD2_k127_6560054_20 Psort location Cytoplasmic, score - - - 0.0000000611 65.0
SHD2_k127_6560054_21 Glutathione peroxidase K02199 - - 0.0000001737 61.0
SHD2_k127_6560054_22 cellulose binding - - - 0.0000002649 64.0
SHD2_k127_6560054_23 amine dehydrogenase activity - - - 0.0000003545 62.0
SHD2_k127_6560054_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 388.0
SHD2_k127_6560054_4 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 314.0
SHD2_k127_6560054_5 4 iron, 4 sulfur cluster binding K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000125 284.0
SHD2_k127_6560054_6 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000011 292.0
SHD2_k127_6560054_7 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000009003 257.0
SHD2_k127_6560054_8 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000137 248.0
SHD2_k127_6560054_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002239 246.0
SHD2_k127_6580296_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 480.0
SHD2_k127_6580296_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 406.0
SHD2_k127_6580296_10 PFAM Membrane protein of K08972 - - 0.000000000000000001775 94.0
SHD2_k127_6580296_2 PFAM Pyridoxal-dependent decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 376.0
SHD2_k127_6580296_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001115 261.0
SHD2_k127_6580296_4 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000004625 192.0
SHD2_k127_6580296_5 ATPases associated with a variety of cellular activities K02074,K09817 - - 0.000000000000000000000000000000000000000000000000153 191.0
SHD2_k127_6580296_6 ABC-type Mn2 Zn2 transport system, permease component K09816,K09819,K19976 - - 0.00000000000000000000000000000000000000000000000108 189.0
SHD2_k127_6580296_7 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000002196 160.0
SHD2_k127_6580296_8 cellulase activity K20276 - - 0.0000000000000000000000000000000000001121 164.0
SHD2_k127_6580296_9 Belongs to the Fur family K03711 - - 0.0000000000000000007368 92.0
SHD2_k127_6649256_0 Bacterial transcriptional activator domain K03556 - - 0.00000000000000000000000000000000000000000000000000000002257 226.0
SHD2_k127_6649256_1 DinB family - - - 0.000000000000000000000000000000000000000001275 162.0
SHD2_k127_6649256_2 negative regulation of transcription, DNA-templated - - - 0.000000000000001565 82.0
SHD2_k127_6649256_3 Passenger-associated-transport-repeat - - - 0.000000000000003797 91.0
SHD2_k127_6649256_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000002384 63.0
SHD2_k127_6657413_0 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000000000002374 237.0
SHD2_k127_6657413_1 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000001156 224.0
SHD2_k127_6667316_0 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 580.0
SHD2_k127_6667316_1 adenosine deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 394.0
SHD2_k127_6667316_10 COG0457 FOG TPR repeat - - - 0.000000003047 70.0
SHD2_k127_6667316_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 320.0
SHD2_k127_6667316_3 Subtilase family K13276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007108 310.0
SHD2_k127_6667316_4 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002484 288.0
SHD2_k127_6667316_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000191 209.0
SHD2_k127_6667316_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000005594 212.0
SHD2_k127_6667316_7 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000002557 197.0
SHD2_k127_6667316_8 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000008469 164.0
SHD2_k127_6667316_9 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000003593 87.0
SHD2_k127_6667349_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000001211 233.0
SHD2_k127_6667349_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000756 191.0
SHD2_k127_6667349_2 S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl K13622 - - 0.00026 53.0
SHD2_k127_6669231_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1230.0
SHD2_k127_6669231_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.007e-234 738.0
SHD2_k127_6669231_10 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 300.0
SHD2_k127_6669231_11 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000001559 278.0
SHD2_k127_6669231_12 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000001455 251.0
SHD2_k127_6669231_13 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004236 256.0
SHD2_k127_6669231_14 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.000000000000000000000000000000000000000000000000000000000001069 231.0
SHD2_k127_6669231_15 Catalyzes the conversion of chorismate to isochorismate K02552 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 5.4.4.2 0.00000000000000000000000000000000000000000000000000000006089 205.0
SHD2_k127_6669231_17 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000119 210.0
SHD2_k127_6669231_18 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000479 182.0
SHD2_k127_6669231_19 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) - - - 0.00000000000000000000000000000000000000000001028 182.0
SHD2_k127_6669231_2 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 4.508e-212 666.0
SHD2_k127_6669231_20 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000004047 117.0
SHD2_k127_6669231_21 protein maturation K13628 - - 0.00000000000000000000000004073 114.0
SHD2_k127_6669231_22 PFAM thioesterase superfamily K12073 - 3.1.2.28 0.0000000000000000000000006282 111.0
SHD2_k127_6669231_23 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000006336 113.0
SHD2_k127_6669231_24 - - - - 0.0000000000000000003484 94.0
SHD2_k127_6669231_25 Carboxylesterase K06999 - - 0.00000000000000001263 96.0
SHD2_k127_6669231_26 methyltransferase - - - 0.000000000004222 74.0
SHD2_k127_6669231_27 Evidence 5 No homology to any previously reported sequences - - - 0.0000000005247 74.0
SHD2_k127_6669231_28 Protease prsW family - - - 0.000000001784 69.0
SHD2_k127_6669231_29 Tetratricopeptide repeat - - - 0.00000000267 71.0
SHD2_k127_6669231_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 505.0
SHD2_k127_6669231_30 transcriptional regulator, SARP family - - - 0.00002032 55.0
SHD2_k127_6669231_4 Enoyl-CoA hydratase/isomerase K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 420.0
SHD2_k127_6669231_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 416.0
SHD2_k127_6669231_6 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 359.0
SHD2_k127_6669231_7 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 347.0
SHD2_k127_6669231_8 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 336.0
SHD2_k127_6669231_9 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 308.0
SHD2_k127_6683450_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 1.045e-289 897.0
SHD2_k127_6683450_1 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 570.0
SHD2_k127_6683450_10 PFAM Glycosyl transferase, group 1 K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.000000000000000000000005028 119.0
SHD2_k127_6683450_2 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 531.0
SHD2_k127_6683450_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 360.0
SHD2_k127_6683450_4 alanine dehydrogenase activity K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 331.0
SHD2_k127_6683450_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 327.0
SHD2_k127_6683450_6 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009294 297.0
SHD2_k127_6683450_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000001305 209.0
SHD2_k127_6683450_8 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000001603 141.0
SHD2_k127_6683450_9 MviN-like protein K03980 - - 0.0000000000000000000000000007695 132.0
SHD2_k127_6686656_0 Aldehyde dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 467.0
SHD2_k127_6686656_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000001651 214.0
SHD2_k127_6686656_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000002344 147.0
SHD2_k127_6686656_3 PFAM Integrase catalytic region K07497 - - 0.00000000000000002028 97.0
SHD2_k127_6689039_0 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000001403 213.0
SHD2_k127_6689039_1 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000032 188.0
SHD2_k127_6689039_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000001994 194.0
SHD2_k127_6689039_3 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000002633 158.0
SHD2_k127_6689039_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000004581 135.0
SHD2_k127_6689039_5 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000003319 109.0
SHD2_k127_6689039_6 Part of the ABC transporter FtsEX involved in K09811 - - 0.00000000000000000006497 101.0
SHD2_k127_6689039_7 pfkB family carbohydrate kinase - - - 0.00000000000001075 84.0
SHD2_k127_6689039_8 S4 RNA-binding domain - GO:0008150,GO:0040007 - 0.0000000007297 64.0
SHD2_k127_6689039_9 Molybdopterin converting factor small subunit K03636 - - 0.000000001204 62.0
SHD2_k127_6704086_0 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 511.0
SHD2_k127_6704086_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 375.0
SHD2_k127_6704086_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 298.0
SHD2_k127_6704086_3 Histidine kinase K11383 - 2.7.13.3 0.00000000000000000000000000000000000004721 159.0
SHD2_k127_6704086_4 TonB dependent receptor - - - 0.000000000000000000000003318 119.0
SHD2_k127_6704086_5 Histidine kinase K14986 - 2.7.13.3 0.000000000000000000003261 97.0
SHD2_k127_6704086_6 PFAM response regulator receiver K02483,K07667 - - 0.0000000000000000001056 100.0
SHD2_k127_6704086_7 Histidine kinase - - - 0.0002323 49.0
SHD2_k127_6723772_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 469.0
SHD2_k127_6723772_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 449.0
SHD2_k127_6723772_10 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768,K02769,K02770 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 0.000000000000000002326 92.0
SHD2_k127_6723772_11 - - - - 0.00000003677 55.0
SHD2_k127_6723772_12 FHA domain - - - 0.00000008422 65.0
SHD2_k127_6723772_13 Peptidase family C25 - - - 0.000597 52.0
SHD2_k127_6723772_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 320.0
SHD2_k127_6723772_3 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 304.0
SHD2_k127_6723772_4 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003235 249.0
SHD2_k127_6723772_5 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000001082 183.0
SHD2_k127_6723772_6 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000006733 158.0
SHD2_k127_6723772_7 Transport permease protein - - - 0.0000000000000000000000000001804 129.0
SHD2_k127_6723772_8 cheY-homologous receiver domain - - - 0.0000000000000000000000001293 111.0
SHD2_k127_6723772_9 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000003399 116.0
SHD2_k127_6733740_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 415.0
SHD2_k127_6757735_0 Glycosyltransferase family 20 K16055 - 2.4.1.15,3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 565.0
SHD2_k127_6757735_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000004571 227.0
SHD2_k127_6757735_2 metallopeptidase activity K06974 - - 0.000000000000000000000000000000000000001375 155.0
SHD2_k127_6757735_3 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000106 152.0
SHD2_k127_6757735_4 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000001591 128.0
SHD2_k127_6757735_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000211 79.0
SHD2_k127_6757735_6 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.00000000006739 72.0
SHD2_k127_6757735_7 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000157 56.0
SHD2_k127_6757990_0 CoA binding domain protein K09181 - - 0.0 1063.0
SHD2_k127_6757990_1 Response regulator, receiver K01007 - 2.7.9.2 6.806e-294 944.0
SHD2_k127_6757990_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 2.001e-213 718.0
SHD2_k127_6757990_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 417.0
SHD2_k127_6757990_4 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002908 277.0
SHD2_k127_6757990_5 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000005429 221.0
SHD2_k127_6757990_6 Histidine kinase K20973 - 2.7.13.3 0.00000000000000000000000003023 116.0
SHD2_k127_6757990_7 Transcriptional regulatory protein, C terminal - - - 0.00000000001137 78.0
SHD2_k127_6757990_8 Glutamine amidotransferases class-II - - - 0.0001277 55.0
SHD2_k127_6758893_0 ATPase (P-type) K01535 - 3.6.3.6 0.0 1289.0
SHD2_k127_6758893_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.947e-202 645.0
SHD2_k127_6758893_10 Integrase core domain - - - 0.00000000000000000000000000001244 120.0
SHD2_k127_6758893_11 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000006622 126.0
SHD2_k127_6758893_12 DGC domain K02437 - - 0.000000000000000000000000003769 116.0
SHD2_k127_6758893_13 regulatory protein, arsR - - - 0.000000000000000000000003431 104.0
SHD2_k127_6758893_14 Tellurite resistance protein TehB - - - 0.000000000000000000000008652 106.0
SHD2_k127_6758893_15 DGC domain - - - 0.00000000000000000000001713 108.0
SHD2_k127_6758893_16 complex i intermediate-associated protein 30 - - - 0.00000000000000000000357 98.0
SHD2_k127_6758893_17 Thioredoxin domain - - - 0.000000000000000001563 89.0
SHD2_k127_6758893_18 transferase activity, transferring glycosyl groups - - - 0.000000000000001058 87.0
SHD2_k127_6758893_19 - - - - 0.00000000000007685 77.0
SHD2_k127_6758893_2 PFAM NAD-dependent epimerase dehydratase - - - 1.406e-198 631.0
SHD2_k127_6758893_20 transferase activity, transferring glycosyl groups - - - 0.0000006001 55.0
SHD2_k127_6758893_21 COG2963 Transposase and inactivated derivatives K07483 - - 0.00003936 56.0
SHD2_k127_6758893_22 COG2801 Transposase and inactivated derivatives - - - 0.00004167 49.0
SHD2_k127_6758893_23 Rubrerythrin - - - 0.0001609 47.0
SHD2_k127_6758893_3 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 479.0
SHD2_k127_6758893_4 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 460.0
SHD2_k127_6758893_5 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000007364 180.0
SHD2_k127_6758893_6 lipid binding K03098 - - 0.000000000000000000000000000000000000000000000002679 184.0
SHD2_k127_6758893_7 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000000000000000381 161.0
SHD2_k127_6758893_8 DGC domain - - - 0.0000000000000000000000000000000002617 146.0
SHD2_k127_6758893_9 OsmC-like protein - - - 0.000000000000000000000000000000004061 139.0
SHD2_k127_6759238_0 Carbamoyltransferase C-terminus K00612 - - 8.123e-270 842.0
SHD2_k127_6759238_1 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 567.0
SHD2_k127_6759238_10 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000004492 69.0
SHD2_k127_6759238_11 - - - - 0.000000001735 65.0
SHD2_k127_6759238_12 COG3119 Arylsulfatase A - - - 0.00000001522 68.0
SHD2_k127_6759238_13 Tetratricopeptide repeat - - - 0.0000005549 63.0
SHD2_k127_6759238_2 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 418.0
SHD2_k127_6759238_3 PFAM sigma-54 factor interaction domain-containing protein K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 404.0
SHD2_k127_6759238_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000001131 220.0
SHD2_k127_6759238_5 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000000000000734 192.0
SHD2_k127_6759238_6 HAMP domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000005708 172.0
SHD2_k127_6759238_7 cellulase activity - - - 0.000000000000000000000000001514 131.0
SHD2_k127_6759238_8 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.000000000000000000000001353 117.0
SHD2_k127_6759238_9 - - - - 0.00000000000000001816 98.0
SHD2_k127_6790705_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 429.0
SHD2_k127_6790705_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 363.0
SHD2_k127_6790705_2 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 288.0
SHD2_k127_6790705_3 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000005655 171.0
SHD2_k127_6790705_4 Protein of unknown function (DUF971) - - - 0.00000000000000000001563 100.0
SHD2_k127_6790705_5 Multidrug Resistance protein - - - 0.000000000000000005592 97.0
SHD2_k127_6790705_6 Membrane - - - 0.00000000606 68.0
SHD2_k127_6790705_7 PPIC-type PPIASE domain K01802,K03769 - 5.2.1.8 0.000002363 61.0
SHD2_k127_6790705_8 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00003776 57.0
SHD2_k127_6790705_9 Peptidase family C25 - - - 0.000083 56.0
SHD2_k127_6832667_0 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 451.0
SHD2_k127_6832667_1 Putative neutral zinc metallopeptidase K06973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009887 252.0
SHD2_k127_6832667_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001294 226.0
SHD2_k127_6832667_3 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000001424 178.0
SHD2_k127_6832667_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000003418 97.0
SHD2_k127_6846645_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 426.0
SHD2_k127_6846645_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 315.0
SHD2_k127_6846645_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000005008 272.0
SHD2_k127_6846645_3 Transcriptional regulator, TraR DksA family K06204 - - 0.00000000000000000000000000000961 123.0
SHD2_k127_6846645_4 phosphatidylinositol metabolic process K13671 - - 0.00000000000000000000000000001694 133.0
SHD2_k127_6846645_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000004 111.0
SHD2_k127_6846645_6 LVIVD repeat - - - 0.000000000000000000000003046 114.0
SHD2_k127_6846645_7 Carboxymuconolactone decarboxylase family - - - 0.00000000000000001443 96.0
SHD2_k127_6846645_8 PFAM DivIVA K04074 - - 0.0000000000000001222 91.0
SHD2_k127_6846645_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000001327 79.0
SHD2_k127_6856787_0 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 374.0
SHD2_k127_6856787_1 biosynthesis protein ThiH K03150 - 4.1.99.19 0.000000000000000000000000000000000000000000002475 173.0
SHD2_k127_6856787_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000016 126.0
SHD2_k127_6856787_3 Anti-sigma-K factor rskA - - - 0.0006602 52.0
SHD2_k127_6866256_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 606.0
SHD2_k127_6866256_1 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000618 271.0
SHD2_k127_6866256_2 PKD domain - - - 0.00000000000006089 86.0
SHD2_k127_6866256_3 Subtilase family - - - 0.00000107 62.0
SHD2_k127_6869392_0 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 382.0
SHD2_k127_6869392_1 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001659 292.0
SHD2_k127_6869392_10 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000001112 123.0
SHD2_k127_6869392_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K05788 - - 0.00000000000000000000000001731 111.0
SHD2_k127_6869392_12 CoA-binding protein K06929 - - 0.00000000000000000000002565 107.0
SHD2_k127_6869392_13 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K10857 - 2.7.7.7 0.0000000000000000000001205 106.0
SHD2_k127_6869392_14 YbbR-like protein - - - 0.0000000009967 69.0
SHD2_k127_6869392_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 273.0
SHD2_k127_6869392_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000171 235.0
SHD2_k127_6869392_4 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000004167 227.0
SHD2_k127_6869392_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000002678 184.0
SHD2_k127_6869392_6 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000003212 171.0
SHD2_k127_6869392_7 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000001732 173.0
SHD2_k127_6869392_8 Memo-like protein K06990 - - 0.00000000000000000000000000001789 131.0
SHD2_k127_6869392_9 CDP-alcohol phosphatidyltransferase K00995,K00999 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 0.0000000000000000000000000001689 122.0
SHD2_k127_6882581_0 Belongs to the peptidase M28 family - - - 0.0000000000000000000000000000003019 143.0
SHD2_k127_6882581_1 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000003928 121.0
SHD2_k127_6882581_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000118 119.0
SHD2_k127_6882581_3 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan - - - 0.000000000561 73.0
SHD2_k127_6882581_4 metallopeptidase activity K01387,K01730,K20276 - 3.4.24.3,4.2.2.6 0.0001819 55.0
SHD2_k127_6908929_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 561.0
SHD2_k127_6908929_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 494.0
SHD2_k127_6908929_2 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 336.0
SHD2_k127_6908929_3 asparaginase activity K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000002762 173.0
SHD2_k127_6908929_4 IMG reference gene - - - 0.000000000000000000000000000000000000000003272 179.0
SHD2_k127_6908929_5 histone H2A K63-linked ubiquitination K10914 - - 0.000000000000000000000000000000004761 139.0
SHD2_k127_6908929_6 radical SAM domain protein - - - 0.0000000000000008379 91.0
SHD2_k127_6908929_7 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000001177 61.0
SHD2_k127_6908929_8 Tetratricopeptide repeat - - - 0.0000003027 64.0
SHD2_k127_6908929_9 Outer membrane efflux protein - - - 0.000001692 58.0
SHD2_k127_6923535_0 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 323.0
SHD2_k127_6923535_1 PFAM lipopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000879 160.0
SHD2_k127_6923535_10 Urate oxidase N-terminal - - - 0.00000001416 62.0
SHD2_k127_6923535_11 PFAM Polysaccharide export protein K01991 - - 0.0001198 54.0
SHD2_k127_6923535_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000001286 128.0
SHD2_k127_6923535_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000002862 119.0
SHD2_k127_6923535_4 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000000000000005856 114.0
SHD2_k127_6923535_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000006666 112.0
SHD2_k127_6923535_6 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000000000000000004299 104.0
SHD2_k127_6923535_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 0.000000000000000000000006397 101.0
SHD2_k127_6923535_9 Redoxin K03564 - 1.11.1.15 0.000000000004877 66.0
SHD2_k127_6924847_0 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006078 292.0
SHD2_k127_6924847_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000001199 224.0
SHD2_k127_6924847_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000001107 116.0
SHD2_k127_6924847_3 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000002404 124.0
SHD2_k127_6924847_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000002207 90.0
SHD2_k127_6942101_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.079e-313 972.0
SHD2_k127_6942101_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 2.735e-213 677.0
SHD2_k127_6942101_10 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000002095 265.0
SHD2_k127_6942101_11 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003016 254.0
SHD2_k127_6942101_12 Coenzyme F420 hydrogenase dehydrogenase, beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000001772 236.0
SHD2_k127_6942101_13 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000002374 210.0
SHD2_k127_6942101_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000004976 171.0
SHD2_k127_6942101_15 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000002129 156.0
SHD2_k127_6942101_16 SMART metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.00000000000000000000000000001801 136.0
SHD2_k127_6942101_17 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000477 123.0
SHD2_k127_6942101_18 ComF family K02242 - - 0.0000000000000000000000001093 115.0
SHD2_k127_6942101_19 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000002171 119.0
SHD2_k127_6942101_2 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 497.0
SHD2_k127_6942101_20 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000005025 99.0
SHD2_k127_6942101_21 Cell shape-determining protein MreC K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.00000000000000000001962 102.0
SHD2_k127_6942101_22 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00000008123 64.0
SHD2_k127_6942101_23 Lipopolysaccharide-assembly, LptC-related - - - 0.0000004668 61.0
SHD2_k127_6942101_3 MreB/Mbl protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 445.0
SHD2_k127_6942101_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 410.0
SHD2_k127_6942101_5 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 410.0
SHD2_k127_6942101_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 386.0
SHD2_k127_6942101_7 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 309.0
SHD2_k127_6942101_8 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001132 298.0
SHD2_k127_6942101_9 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001632 287.0
SHD2_k127_6954223_0 Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 289.0
SHD2_k127_6954223_1 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004505 296.0
SHD2_k127_6954223_2 protein secretion - - - 0.00003487 47.0
SHD2_k127_6968628_0 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000001357 221.0
SHD2_k127_6982240_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 314.0
SHD2_k127_6982240_1 binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002746 247.0
SHD2_k127_6982240_2 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000005925 194.0
SHD2_k127_6982240_4 Pectate lyase K01179 - 3.2.1.4 0.00000000000000000268 98.0
SHD2_k127_6994029_0 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000001347 193.0
SHD2_k127_6994029_1 - - - - 0.00000000002762 68.0
SHD2_k127_6994029_2 Wd40 repeat-containing protein - - - 0.000004147 59.0
SHD2_k127_6998228_0 C-terminal AAA-associated domain K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 533.0
SHD2_k127_6998228_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 366.0
SHD2_k127_6998228_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 323.0
SHD2_k127_6998228_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 232.0
SHD2_k127_6998228_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000003598 89.0
SHD2_k127_7032295_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.907e-202 650.0
SHD2_k127_7032295_1 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 410.0
SHD2_k127_7032295_2 HD domain - - - 0.000000000000000000000000000000000000003556 165.0
SHD2_k127_7032295_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000004792 57.0
SHD2_k127_70448_0 RNA recognition motif - - - 0.000000000000000000000000000000000005076 139.0
SHD2_k127_70448_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000001056 114.0
SHD2_k127_70448_2 - - - - 0.00000000000001949 78.0
SHD2_k127_7048348_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 2.768e-197 647.0
SHD2_k127_7048348_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 580.0
SHD2_k127_7048348_10 Methylamine utilisation protein MauE - - - 0.0000000000000004094 89.0
SHD2_k127_7048348_11 chlorophyll binding K16191,K20276 - - 0.0000000000000008504 89.0
SHD2_k127_7048348_12 - - - - 0.0000000009961 64.0
SHD2_k127_7048348_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000005042 66.0
SHD2_k127_7048348_14 Rhodanese Homology Domain - - - 0.000006622 55.0
SHD2_k127_7048348_15 PQQ enzyme repeat - - - 0.00008426 55.0
SHD2_k127_7048348_2 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 484.0
SHD2_k127_7048348_3 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 433.0
SHD2_k127_7048348_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 368.0
SHD2_k127_7048348_5 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009342 347.0
SHD2_k127_7048348_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000005722 205.0
SHD2_k127_7048348_7 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000001937 179.0
SHD2_k127_7048348_8 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000007075 156.0
SHD2_k127_7048348_9 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.0000000000000000005269 93.0
SHD2_k127_7079351_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 1814.0
SHD2_k127_7086745_0 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 424.0
SHD2_k127_7086745_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 376.0
SHD2_k127_7086745_2 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008721 291.0
SHD2_k127_7086745_3 PFAM PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009149 261.0
SHD2_k127_7086745_4 PFAM Glycosyltransferase 28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005196 260.0
SHD2_k127_7086745_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000004862 131.0
SHD2_k127_7086745_6 Sigma-54 interaction domain - - - 0.00000001764 59.0
SHD2_k127_7086745_7 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00002961 58.0
SHD2_k127_7199617_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 363.0
SHD2_k127_7199617_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 314.0
SHD2_k127_7247250_0 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 492.0
SHD2_k127_7247250_1 Cystathionine beta-synthase K01697 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 466.0
SHD2_k127_7247250_10 HEPN domain K00392 - 1.8.7.1 0.00000005619 61.0
SHD2_k127_7247250_11 Elongation factor Tu GTP binding domain - - - 0.0000002749 62.0
SHD2_k127_7247250_12 C-terminal domain of CHU protein family K20276 - - 0.0005604 55.0
SHD2_k127_7247250_2 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 390.0
SHD2_k127_7247250_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000003239 279.0
SHD2_k127_7247250_4 membrane protein (homolog of Drosophila rhomboid) - - - 0.0000000000000000000000000000000000000000000000000000000354 204.0
SHD2_k127_7247250_5 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000002202 217.0
SHD2_k127_7247250_6 5'-nucleotidase - - - 0.000000000000000000000000000007129 133.0
SHD2_k127_7247250_7 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.00000000000004106 78.0
SHD2_k127_7247250_8 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000004192 79.0
SHD2_k127_7247250_9 extracellular matrix structural constituent - - - 0.000000001836 73.0
SHD2_k127_7248403_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001153 240.0
SHD2_k127_7304841_0 TIGRFAM ornithine aminotransferase K00819 - 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 580.0
SHD2_k127_7304841_1 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 323.0
SHD2_k127_7304841_2 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002534 251.0
SHD2_k127_7304841_3 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000003287 224.0
SHD2_k127_7304841_4 Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000003183 225.0
SHD2_k127_7304841_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000004398 137.0
SHD2_k127_7304841_6 Peptidase family M48 - - - 0.000000000000000000003023 110.0
SHD2_k127_7304841_7 Tetratricopeptide repeat - - - 0.000000000000000002518 100.0
SHD2_k127_731683_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 527.0
SHD2_k127_7398428_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 535.0
SHD2_k127_7398428_1 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 540.0
SHD2_k127_7398428_10 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002901 281.0
SHD2_k127_7398428_11 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000002927 273.0
SHD2_k127_7398428_12 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000007196 217.0
SHD2_k127_7398428_13 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000003377 205.0
SHD2_k127_7398428_14 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000009327 172.0
SHD2_k127_7398428_15 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000003924 172.0
SHD2_k127_7398428_16 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000283 153.0
SHD2_k127_7398428_17 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000001187 152.0
SHD2_k127_7398428_18 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K00627,K01571,K02160 - 2.3.1.12,4.1.1.3 0.000000000000000000000000000000000288 137.0
SHD2_k127_7398428_19 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000007183 130.0
SHD2_k127_7398428_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 435.0
SHD2_k127_7398428_20 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000003649 109.0
SHD2_k127_7398428_21 methyltransferase - - - 0.0000000000000000000001182 111.0
SHD2_k127_7398428_22 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000164 105.0
SHD2_k127_7398428_23 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000002114 79.0
SHD2_k127_7398428_24 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000002371 89.0
SHD2_k127_7398428_25 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.0000000000000003535 91.0
SHD2_k127_7398428_26 Domain of unknown function (DUF4349) - - - 0.0002224 51.0
SHD2_k127_7398428_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 429.0
SHD2_k127_7398428_4 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 400.0
SHD2_k127_7398428_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 394.0
SHD2_k127_7398428_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 383.0
SHD2_k127_7398428_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 332.0
SHD2_k127_7398428_8 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004646 291.0
SHD2_k127_7398428_9 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003038 280.0
SHD2_k127_7413893_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000001575 256.0
SHD2_k127_7413893_1 phosphatidylcholine synthase K01004 - 2.7.8.24 0.00000000007252 72.0
SHD2_k127_7413893_2 Peptidogalycan biosysnthesis/recognition - - - 0.000002286 60.0
SHD2_k127_7456093_0 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000007192 171.0
SHD2_k127_7456093_2 PFAM Alpha beta hydrolase of - - - 0.0006113 50.0
SHD2_k127_7486480_0 agmatine deiminase activity K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 323.0
SHD2_k127_7486480_1 histone H2A K63-linked ubiquitination K10914 - - 0.0000000000000000000000000000000000000000000003949 176.0
SHD2_k127_7486480_3 Glycosyl hydrolase family 70 K01142,K01176 - 3.1.11.2,3.2.1.1 0.00000000000000008947 94.0
SHD2_k127_7486480_4 Outer membrane protein beta-barrel domain - - - 0.000118 56.0
SHD2_k127_7486480_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0008605 49.0
SHD2_k127_7508774_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 300.0
SHD2_k127_7508774_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000002057 250.0
SHD2_k127_7508774_10 - - - - 0.00005127 46.0
SHD2_k127_7508774_2 lyase activity K01387,K03301 - 3.4.24.3 0.0000000000000000000000000000000000000000000000000000000000000000000003151 261.0
SHD2_k127_7508774_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000008223 208.0
SHD2_k127_7508774_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000009413 195.0
SHD2_k127_7508774_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000002199 165.0
SHD2_k127_7508774_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000002844 149.0
SHD2_k127_7508774_7 peroxiredoxin activity - - - 0.000000000000000000000002891 109.0
SHD2_k127_7508774_8 - - - - 0.0000000007917 63.0
SHD2_k127_7508774_9 Sporulation and spore germination - - - 0.0000002173 63.0
SHD2_k127_7515838_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 540.0
SHD2_k127_7515838_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13308,K20429 GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771 2.6.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000137 294.0
SHD2_k127_7515838_10 biopolymer transport protein K03559 - - 0.000000000000000000000000000000001553 135.0
SHD2_k127_7515838_11 biopolymer transport protein - - - 0.000000000000000000000000000005073 124.0
SHD2_k127_7515838_12 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000009937 125.0
SHD2_k127_7515838_13 Involved in resistance toward heavy metals K03926 GO:0003674,GO:0005488,GO:0005507,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840 - 0.00000000000000000000000001264 114.0
SHD2_k127_7515838_14 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000000004539 110.0
SHD2_k127_7515838_15 STAS domain - - - 0.00000000000000000001652 94.0
SHD2_k127_7515838_16 -O-antigen - - - 0.00000000000005908 85.0
SHD2_k127_7515838_17 C-terminal domain of histone - - - 0.0000000000001846 78.0
SHD2_k127_7515838_18 TPR repeat - - - 0.0000000001981 75.0
SHD2_k127_7515838_19 PBP superfamily domain K02040 - - 0.0000000009505 70.0
SHD2_k127_7515838_2 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000006156 239.0
SHD2_k127_7515838_20 Psort location CytoplasmicMembrane, score K03558 - - 0.000000001089 67.0
SHD2_k127_7515838_21 cellulase activity - - - 0.0000002861 63.0
SHD2_k127_7515838_22 Histidine kinase - - - 0.0000003597 63.0
SHD2_k127_7515838_23 Protein of unknown function (DUF3485) - - - 0.000000419 63.0
SHD2_k127_7515838_24 - - - - 0.0001503 53.0
SHD2_k127_7515838_25 PFAM TPR repeat-containing protein - - - 0.0004647 53.0
SHD2_k127_7515838_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000008151 242.0
SHD2_k127_7515838_4 sugar transferase - - - 0.00000000000000000000000000000000000000000000000000232 205.0
SHD2_k127_7515838_5 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000000001006 184.0
SHD2_k127_7515838_6 eight transmembrane protein EpsH - - - 0.000000000000000000000000000000000000000801 169.0
SHD2_k127_7515838_7 AI-2E family transporter - - - 0.000000000000000000000000000000000000001567 164.0
SHD2_k127_7515838_8 AAA domain K16554 - - 0.00000000000000000000000000000000001088 156.0
SHD2_k127_7515838_9 transport system involved in gliding motility auxiliary component-like K01992 - - 0.00000000000000000000000000000000001191 151.0
SHD2_k127_7523093_0 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 452.0
SHD2_k127_7523093_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 376.0
SHD2_k127_7523093_2 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 326.0
SHD2_k127_7523093_3 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000008146 247.0
SHD2_k127_7523093_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000001336 189.0
SHD2_k127_7523093_5 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000008065 172.0
SHD2_k127_7523093_6 NUDIX domain - - - 0.0000000000000000000000000000003183 131.0
SHD2_k127_7523093_7 phosphorelay sensor kinase activity K13924 - 2.1.1.80,3.1.1.61 0.000000000000000004752 94.0
SHD2_k127_7523093_8 - - - - 0.0000007783 59.0
SHD2_k127_7523093_9 Protein of unknown function (DUF2752) - - - 0.000002282 55.0
SHD2_k127_7553599_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 1.368e-238 760.0
SHD2_k127_7553599_1 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 343.0
SHD2_k127_7553599_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000843 134.0
SHD2_k127_7553599_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000004648 83.0
SHD2_k127_7553599_12 IrrE N-terminal-like domain - - - 0.000000004132 68.0
SHD2_k127_7553599_13 Glycosyl transferase 4-like domain - - - 0.00000001436 67.0
SHD2_k127_7553599_14 guanyl-nucleotide exchange factor activity - - - 0.00000002397 65.0
SHD2_k127_7553599_16 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.000001185 58.0
SHD2_k127_7553599_17 long-chain fatty acid transporting porin activity - - - 0.000001831 55.0
SHD2_k127_7553599_18 - - - - 0.00000726 56.0
SHD2_k127_7553599_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 314.0
SHD2_k127_7553599_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 301.0
SHD2_k127_7553599_4 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 295.0
SHD2_k127_7553599_5 BtpA family K06971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002204 284.0
SHD2_k127_7553599_6 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000003334 243.0
SHD2_k127_7553599_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000001229 239.0
SHD2_k127_7553599_8 PFAM sigma-54 factor interaction domain-containing protein K10126,K10941 - - 0.000000000000000000000000000000000000000000000000000000000006611 232.0
SHD2_k127_7553599_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000032 224.0
SHD2_k127_7565806_0 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000001328 204.0
SHD2_k127_7565806_1 Cold shock K03704 GO:0001072,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0003727,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008143,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043242,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051087,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0070717,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000002286 98.0
SHD2_k127_7565806_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.00000001722 68.0
SHD2_k127_7566313_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1051.0
SHD2_k127_7566313_1 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 3.057e-261 816.0
SHD2_k127_7566313_2 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 449.0
SHD2_k127_7566313_3 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 317.0
SHD2_k127_7566313_4 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.0000000000000000000000000000000000000000002154 174.0
SHD2_k127_7566313_5 Alginate export - - - 0.0000000000000000000000000000001561 139.0
SHD2_k127_7566313_6 anti-sigma regulatory factor - - - 0.000000000000000000000000000001967 123.0
SHD2_k127_7574331_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.006e-315 980.0
SHD2_k127_7574331_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.188e-260 827.0
SHD2_k127_7574331_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 490.0
SHD2_k127_7574331_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000003665 220.0
SHD2_k127_7574331_4 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000006014 162.0
SHD2_k127_7574331_5 TIGRFAM 2-oxoglutarate dehydrogenase, E2 component K00658 - 2.3.1.61 0.00000000000000000000000009426 112.0
SHD2_k127_7574331_6 GAF domain - - - 0.00005142 55.0
SHD2_k127_7599353_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 321.0
SHD2_k127_7599353_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000007952 88.0
SHD2_k127_7612517_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 6.135e-307 955.0
SHD2_k127_7634837_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008017 281.0
SHD2_k127_7634837_1 PFAM Transmembrane proteins 14C - - - 0.0000000000007519 73.0
SHD2_k127_7634837_2 extracellular matrix structural constituent - - - 0.0000000002116 74.0
SHD2_k127_7670972_0 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 516.0
SHD2_k127_7670972_1 Glycosyl transferases group 1 - - - 0.00000000000000000003025 96.0
SHD2_k127_7670972_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000002829 75.0
SHD2_k127_7670972_4 - - - - 0.000000001003 63.0
SHD2_k127_7689734_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 351.0
SHD2_k127_7689734_1 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 317.0
SHD2_k127_7689734_2 Putative modulator of DNA gyrase K03592 - - 0.000004821 60.0
SHD2_k127_7697737_0 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000065 274.0
SHD2_k127_7697737_1 amine dehydrogenase activity K20276,K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000002463 255.0
SHD2_k127_7697737_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000005227 224.0
SHD2_k127_7697737_3 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000003017 177.0
SHD2_k127_7697737_4 pectinesterase activity K10117 - - 0.00000000000000007629 96.0
SHD2_k127_7697737_5 DinB family - - - 0.000006357 59.0
SHD2_k127_7754409_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 9.01e-302 940.0
SHD2_k127_7754409_1 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 587.0
SHD2_k127_7754409_10 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 319.0
SHD2_k127_7754409_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 316.0
SHD2_k127_7754409_12 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 299.0
SHD2_k127_7754409_13 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 291.0
SHD2_k127_7754409_14 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004599 254.0
SHD2_k127_7754409_15 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000001328 230.0
SHD2_k127_7754409_16 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000008838 228.0
SHD2_k127_7754409_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000001864 216.0
SHD2_k127_7754409_18 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000001724 218.0
SHD2_k127_7754409_19 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000001116 204.0
SHD2_k127_7754409_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 503.0
SHD2_k127_7754409_20 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000001581 162.0
SHD2_k127_7754409_21 haloacid dehalogenase-like hydrolase K01091 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 0.00000000000000000000000000000000000000002689 161.0
SHD2_k127_7754409_22 protein-(glutamine-N5) methyltransferase activity - - - 0.000000000000000000000000009306 124.0
SHD2_k127_7754409_23 DinB superfamily - - - 0.000000000000000000000001045 110.0
SHD2_k127_7754409_24 PspC domain K03973 - - 0.000000000000000005501 85.0
SHD2_k127_7754409_25 Methyltransferase domain - - - 0.0000000000000009996 88.0
SHD2_k127_7754409_26 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000002822 85.0
SHD2_k127_7754409_27 acyl carrier protein - - - 0.00000001459 62.0
SHD2_k127_7754409_28 Rdx family K07401 - - 0.00000001946 57.0
SHD2_k127_7754409_29 - - - - 0.000008983 57.0
SHD2_k127_7754409_3 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 449.0
SHD2_k127_7754409_4 belongs to the iron- containing alcohol dehydrogenase family K04072 - 1.1.1.1,1.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 426.0
SHD2_k127_7754409_5 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 405.0
SHD2_k127_7754409_6 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 401.0
SHD2_k127_7754409_7 drug transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 372.0
SHD2_k127_7754409_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 358.0
SHD2_k127_7754409_9 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 334.0
SHD2_k127_7769366_0 Peptidylprolyl isomerase K01802,K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000002501 237.0
SHD2_k127_7769366_1 Polysaccharide biosynthesis C-terminal domain - - - 0.000000000000000000000000000000001315 146.0
SHD2_k127_7769366_2 methyltransferase - - - 0.000000000000000000000000000001838 128.0
SHD2_k127_7769366_3 FemAB family - - - 0.00000000000000001131 98.0
SHD2_k127_7801044_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 398.0
SHD2_k127_7801044_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 321.0
SHD2_k127_7801044_11 - - - - 0.0001043 55.0
SHD2_k127_7801044_12 - - - - 0.0001147 53.0
SHD2_k127_7801044_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000001576 246.0
SHD2_k127_7801044_3 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000005257 218.0
SHD2_k127_7801044_4 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 0.0000000000000000000000000000000000000000000001191 189.0
SHD2_k127_7801044_5 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000000000000000008671 158.0
SHD2_k127_7801044_6 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000391 150.0
SHD2_k127_7801044_7 DinB family - - - 0.00000000000000000000000000003789 126.0
SHD2_k127_7801044_8 AsnC family - - - 0.00000000000000000000000008787 109.0
SHD2_k127_7801044_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000004368 110.0
SHD2_k127_7881036_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000887 222.0
SHD2_k127_7881036_1 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000001215 228.0
SHD2_k127_7881036_2 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000001831 144.0
SHD2_k127_7881036_3 Elements of external origin K07497 - - 0.00000000000000000001608 100.0
SHD2_k127_7881036_4 Belongs to the peptidase S8 family - - - 0.0000063 60.0
SHD2_k127_788751_0 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 501.0
SHD2_k127_788751_1 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 349.0
SHD2_k127_788751_2 deoxyhypusine monooxygenase activity K08884 - 2.7.11.1 0.000000000000000000000000001906 128.0
SHD2_k127_788751_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000001525 80.0
SHD2_k127_788751_4 - - - - 0.0000000002355 71.0
SHD2_k127_7888936_0 MutL protein K00854 - 2.7.1.17 8.328e-255 799.0
SHD2_k127_7888936_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 557.0
SHD2_k127_7888936_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 522.0
SHD2_k127_7888936_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 415.0
SHD2_k127_7888936_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 357.0
SHD2_k127_7888936_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000004873 149.0
SHD2_k127_7888936_6 - - - - 0.00000000000000000003209 106.0
SHD2_k127_7888936_7 - - - - 0.0000000000000001288 90.0
SHD2_k127_7888936_8 - - - - 0.00000000006459 76.0
SHD2_k127_7904318_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 5.578e-291 923.0
SHD2_k127_7904318_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 5.682e-273 874.0
SHD2_k127_7904318_10 peroxiredoxin activity - - - 0.0000000000000000000000000000007733 129.0
SHD2_k127_7904318_11 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000001186 136.0
SHD2_k127_7904318_12 ligase activity, forming carbon-carbon bonds K00627,K00645,K01572,K02160 - 2.3.1.12,2.3.1.39,4.1.1.3 0.0000000000000000000004675 103.0
SHD2_k127_7904318_13 - - - - 0.00000000000000003005 91.0
SHD2_k127_7904318_14 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000004027 82.0
SHD2_k127_7904318_15 Papain family cysteine protease K14647 - - 0.0000001714 64.0
SHD2_k127_7904318_2 PFAM carboxyl transferase K01615 - 4.1.1.70 4.547e-248 777.0
SHD2_k127_7904318_3 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 533.0
SHD2_k127_7904318_4 PolyA polymerase K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 385.0
SHD2_k127_7904318_5 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 372.0
SHD2_k127_7904318_6 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 349.0
SHD2_k127_7904318_7 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000006644 265.0
SHD2_k127_7904318_8 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000233 224.0
SHD2_k127_7904318_9 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000009256 159.0
SHD2_k127_7919553_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 513.0
SHD2_k127_7919553_1 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 489.0
SHD2_k127_7919553_10 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001567 291.0
SHD2_k127_7919553_11 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003358 264.0
SHD2_k127_7919553_12 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000004871 257.0
SHD2_k127_7919553_13 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004267 249.0
SHD2_k127_7919553_14 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000009369 241.0
SHD2_k127_7919553_15 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000002239 248.0
SHD2_k127_7919553_16 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000001207 226.0
SHD2_k127_7919553_17 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000001141 224.0
SHD2_k127_7919553_18 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000003887 213.0
SHD2_k127_7919553_19 SAM-dependent methyltransferase - - - 0.0000000000000000000000000000000000000003297 158.0
SHD2_k127_7919553_2 transferase activity, transferring glycosyl groups K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 381.0
SHD2_k127_7919553_20 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000004504 153.0
SHD2_k127_7919553_21 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000009886 144.0
SHD2_k127_7919553_22 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000001627 124.0
SHD2_k127_7919553_23 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000002953 125.0
SHD2_k127_7919553_24 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000003286 124.0
SHD2_k127_7919553_25 Histidine kinase - - - 0.00000000000000000000000005138 123.0
SHD2_k127_7919553_26 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.000000000000000000004361 108.0
SHD2_k127_7919553_27 - - - - 0.00000000000003783 82.0
SHD2_k127_7919553_28 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000002655 60.0
SHD2_k127_7919553_29 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000001842 59.0
SHD2_k127_7919553_3 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 374.0
SHD2_k127_7919553_30 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.000002304 59.0
SHD2_k127_7919553_31 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00001213 51.0
SHD2_k127_7919553_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 333.0
SHD2_k127_7919553_5 PFAM Metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 310.0
SHD2_k127_7919553_6 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 312.0
SHD2_k127_7919553_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 327.0
SHD2_k127_7919553_8 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 314.0
SHD2_k127_7919553_9 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000512 300.0
SHD2_k127_7932577_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 520.0
SHD2_k127_7932577_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007959 442.0
SHD2_k127_7932577_10 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0001264 55.0
SHD2_k127_7932577_11 PTS system sorbose-specific iic component K02795 - - 0.0003535 52.0
SHD2_k127_7932577_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 310.0
SHD2_k127_7932577_3 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000002109 192.0
SHD2_k127_7932577_4 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000004077 152.0
SHD2_k127_7932577_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000008402 114.0
SHD2_k127_7932577_6 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000000007789 98.0
SHD2_k127_7932577_7 PTS mannose transporter subunit IID K02793,K02794,K11194 - 2.7.1.191,2.7.1.202 0.000000000000001762 81.0
SHD2_k127_7932577_8 PTS system sorbose subfamily IIB component K19507 - - 0.00000000000006913 85.0
SHD2_k127_7932577_9 system, mannose fructose sorbose family IID component K02747 - - 0.0000003325 63.0
SHD2_k127_7934837_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 391.0
SHD2_k127_7934837_1 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 349.0
SHD2_k127_7934837_2 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000008412 203.0
SHD2_k127_7934837_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000001451 181.0
SHD2_k127_7934837_4 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000001395 105.0
SHD2_k127_7934837_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000000001482 84.0
SHD2_k127_7940170_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 3.715e-214 674.0
SHD2_k127_7940170_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 529.0
SHD2_k127_7940170_10 Carboxypeptidase regulatory-like domain - - - 0.000004569 61.0
SHD2_k127_7940170_11 Amb_all K01728 - 4.2.2.2 0.00003892 55.0
SHD2_k127_7940170_2 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 436.0
SHD2_k127_7940170_3 Major facilitator Superfamily K16210 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 356.0
SHD2_k127_7940170_4 Memo-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 331.0
SHD2_k127_7940170_5 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004905 248.0
SHD2_k127_7940170_6 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000004965 252.0
SHD2_k127_7940170_7 PhoD-like phosphatase - - - 0.0000000000000000000000000000000000000000000000000000004643 215.0
SHD2_k127_7940170_8 nucleotide catabolic process K05996 - 3.4.17.18 0.0000000000000001218 95.0
SHD2_k127_7940170_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000691 63.0
SHD2_k127_798_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K06987,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 336.0
SHD2_k127_798_1 Phosphoserine phosphatase K01079 GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.3 0.000000000000000000001572 104.0
SHD2_k127_798_2 Putative zinc ribbon domain - - - 0.00000000000001228 82.0
SHD2_k127_7989239_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 9.019e-254 792.0
SHD2_k127_7989239_1 Dehydrogenase E1 component K11381 - 1.2.4.4 6.063e-211 677.0
SHD2_k127_7989239_10 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000002808 92.0
SHD2_k127_7989239_11 endonuclease activity K07451 - - 0.00000000001954 67.0
SHD2_k127_7989239_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 372.0
SHD2_k127_7989239_3 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002188 287.0
SHD2_k127_7989239_4 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000119 265.0
SHD2_k127_7989239_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000004507 224.0
SHD2_k127_7989239_6 transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000001164 227.0
SHD2_k127_7989239_7 Protein of unknown function (DUF3179) - - - 0.00000000000000000000000000000000000000000000000000001872 210.0
SHD2_k127_7989239_8 Cytochrome oxidase assembly protein K02259,K03110 - - 0.00000000000000000000000000000000000000002933 169.0
SHD2_k127_7989239_9 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000003704 104.0
SHD2_k127_8028421_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000001224 166.0
SHD2_k127_8053728_0 Secretin and TonB N terminus short domain - - - 0.0000001764 65.0
SHD2_k127_8053728_1 - - - - 0.000001914 59.0
SHD2_k127_8053728_2 - - - - 0.000002009 61.0
SHD2_k127_8053728_3 Non-ribosomal peptide synthetase modules and related proteins - - - 0.00002808 57.0
SHD2_k127_8053728_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K22110 - - 0.00004814 56.0
SHD2_k127_8072487_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 447.0
SHD2_k127_8072487_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 421.0
SHD2_k127_8072487_10 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000003153 147.0
SHD2_k127_8072487_11 NUDIX domain - - - 0.0000000000000000000000000316 117.0
SHD2_k127_8072487_12 protein conserved in bacteria K09859 - - 0.0000000000000000000002921 111.0
SHD2_k127_8072487_13 - - - - 0.0000000007843 67.0
SHD2_k127_8072487_14 cellulose binding - - - 0.00000001839 66.0
SHD2_k127_8072487_15 cellulose binding K00505 - 1.14.18.1 0.00003695 55.0
SHD2_k127_8072487_2 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 383.0
SHD2_k127_8072487_3 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 348.0
SHD2_k127_8072487_4 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 297.0
SHD2_k127_8072487_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 290.0
SHD2_k127_8072487_6 KR domain K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000001699 210.0
SHD2_k127_8072487_7 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337,K21008 GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000001194 204.0
SHD2_k127_8072487_8 Conserved protein of dim6 ntab family - - - 0.0000000000000000000000000000000000000000000000001545 185.0
SHD2_k127_8072487_9 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000002065 152.0
SHD2_k127_8092118_0 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000194 263.0
SHD2_k127_8092118_1 - - - - 0.000000000000000000000000000000000000000000000003772 192.0
SHD2_k127_8092118_2 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000001622 164.0
SHD2_k127_8092118_3 phosphohistidine phosphatase, SixA K08296 - - 0.0000006385 58.0
SHD2_k127_8092118_4 PFAM Peptidase family M20 M25 M40 K01436 - - 0.00007494 46.0
SHD2_k127_8092118_5 Putative sugar-binding domain K05346 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0007824 51.0
SHD2_k127_8119740_0 aconitate hydratase K01681 - 4.2.1.3 7.477e-317 986.0
SHD2_k127_8119740_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 352.0
SHD2_k127_8119740_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001757 278.0
SHD2_k127_8119740_3 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000003698 166.0
SHD2_k127_8119740_4 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000001207 132.0
SHD2_k127_8171142_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1350.0
SHD2_k127_8171142_1 - - - - 0.0000000000000000000000000000001586 130.0
SHD2_k127_8171142_2 Evidence 5 No homology to any previously reported sequences K20952 - - 0.000000000000000000000009884 117.0
SHD2_k127_8171142_3 Belongs to the peptidase M10A family K08002,K08006 - - 0.00000001942 67.0
SHD2_k127_8171142_4 - - - - 0.0001166 53.0
SHD2_k127_8171142_5 PFAM SNARE associated Golgi protein - - - 0.0006651 43.0
SHD2_k127_818562_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1197.0
SHD2_k127_818562_1 PFAM Cytochrome c assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 561.0
SHD2_k127_818562_10 cellulose binding - - - 0.0000000000009579 79.0
SHD2_k127_818562_11 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000001041 80.0
SHD2_k127_818562_12 Transcription factor zinc-finger K09981 - - 0.0000001478 62.0
SHD2_k127_818562_2 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000001361 226.0
SHD2_k127_818562_3 Metal-dependent phosphoesterase K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000615 226.0
SHD2_k127_818562_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000002625 232.0
SHD2_k127_818562_5 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000002006 228.0
SHD2_k127_818562_6 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000385 198.0
SHD2_k127_818562_7 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000005734 196.0
SHD2_k127_818562_8 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000001008 196.0
SHD2_k127_818562_9 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000617 101.0
SHD2_k127_8249813_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 7.527e-296 920.0
SHD2_k127_8249813_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 8.297e-261 827.0
SHD2_k127_8249813_2 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 521.0
SHD2_k127_8249813_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 374.0
SHD2_k127_8249813_4 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 303.0
SHD2_k127_8249813_5 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000003374 251.0
SHD2_k127_8249813_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000001283 229.0
SHD2_k127_8249813_7 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.000000000000000000000000000000000000002741 164.0
SHD2_k127_8249813_8 - - - - 0.000001047 61.0
SHD2_k127_850003_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1033.0
SHD2_k127_850003_1 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 3.347e-200 642.0
SHD2_k127_850003_10 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001716 245.0
SHD2_k127_850003_11 - - - - 0.00000000000000000000000000000000000000000000000000008196 205.0
SHD2_k127_850003_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000002234 155.0
SHD2_k127_850003_13 Transporter associated domain - - - 0.000000000000000000000000000000000003831 151.0
SHD2_k127_850003_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000003264 144.0
SHD2_k127_850003_15 diguanylate cyclase - - - 0.0000000000000000000000000000128 134.0
SHD2_k127_850003_16 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000001307 126.0
SHD2_k127_850003_17 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768 - 2.7.1.202 0.00000000000000000000000128 109.0
SHD2_k127_850003_18 Propeptide_C25 - - - 0.00000000000000000000002702 117.0
SHD2_k127_850003_19 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000001267 95.0
SHD2_k127_850003_2 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 528.0
SHD2_k127_850003_20 CBS domain containing protein K06189 - - 0.000000000000000000583 98.0
SHD2_k127_850003_21 VanZ like family - - - 0.0000000001797 69.0
SHD2_k127_850003_22 Bacterial Ig-like domain (group 1) - - - 0.000003906 59.0
SHD2_k127_850003_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 419.0
SHD2_k127_850003_4 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 398.0
SHD2_k127_850003_5 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 328.0
SHD2_k127_850003_6 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 343.0
SHD2_k127_850003_7 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 321.0
SHD2_k127_850003_8 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 312.0
SHD2_k127_850003_9 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001688 273.0
SHD2_k127_883230_0 PFAM Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 299.0
SHD2_k127_883230_1 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001148 288.0
SHD2_k127_883230_2 PhoQ Sensor - - - 0.000000000000000000000000000000000001607 160.0
SHD2_k127_883230_3 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000001943 133.0
SHD2_k127_883230_4 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000003048 113.0
SHD2_k127_883230_5 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000007507 79.0
SHD2_k127_936918_0 Tripeptidyl peptidase II K01280 - 3.4.14.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 337.0
SHD2_k127_936918_1 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000002698 154.0
SHD2_k127_936918_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000001319 143.0
SHD2_k127_936918_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000549 138.0
SHD2_k127_936918_4 - - - - 0.0000000000001056 76.0
SHD2_k127_958500_0 peptidase activity, acting on L-amino acid peptides K01448,K07260,K09955,K13276 GO:0005575,GO:0005576 3.4.17.14,3.5.1.28 0.0000000000004071 83.0