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Overview

ID MAG03382
Name SHD2_bin.7
Sample SMP0083
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Anaerolineales
Family Villigracilaceae
Genus Defluviilinea
Species
Assembly information
Completeness (%) 57.78
Contamination (%) 1.51
GC content (%) 53.0
N50 (bp) 7,709
Genome size (bp) 3,361,312

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3197

Gene name Description KEGG GOs EC E-value Score Sequence
SHD2_k127_100286_0 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 435.0
SHD2_k127_100286_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 385.0
SHD2_k127_100286_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 359.0
SHD2_k127_100286_3 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 300.0
SHD2_k127_100286_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000001131 224.0
SHD2_k127_100286_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000005102 229.0
SHD2_k127_100286_6 DNA-binding transcription factor activity K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000613 199.0
SHD2_k127_100286_7 Glycoside hydrolase family 16 - - - 0.00000000000000000000000000000000000000000000004732 176.0
SHD2_k127_100286_8 transcriptional regulator - - - 0.000000000000000000000000000000000001041 146.0
SHD2_k127_100286_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000001429 137.0
SHD2_k127_1079933_0 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 615.0
SHD2_k127_1079933_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 344.0
SHD2_k127_1079933_2 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 335.0
SHD2_k127_1079933_3 sequence-specific DNA binding - - - 0.000000000000000000000000003706 118.0
SHD2_k127_1079933_4 - - - - 0.0000000000000000000001128 101.0
SHD2_k127_1079933_5 Pilus assembly protein TadZ N-terminal K02282 - - 0.0000000000000007196 90.0
SHD2_k127_1082548_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.941e-248 774.0
SHD2_k127_1082548_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000002207 267.0
SHD2_k127_1082548_2 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001576 246.0
SHD2_k127_1090281_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 324.0
SHD2_k127_1090281_1 - - - - 0.000000000000000000000000000000000000001954 154.0
SHD2_k127_1090281_3 - - - - 0.0006183 48.0
SHD2_k127_1092733_0 DEAD DEAH box helicase domain protein K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 530.0
SHD2_k127_1092733_1 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003602 278.0
SHD2_k127_1092733_2 PFAM peptidase, membrane zinc metallopeptidase K06973 - - 0.0000000000000000000000000000000000000000000000000000000000000006303 226.0
SHD2_k127_1092733_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000162 190.0
SHD2_k127_1093746_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 403.0
SHD2_k127_1093746_1 Domain of unknown function (DUF4870) - - - 0.00000000000000000000000000000000000001201 147.0
SHD2_k127_1093746_2 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000001134 122.0
SHD2_k127_1093746_3 Protein of unknown function (DUF4013) - - - 0.000000000000000000001293 104.0
SHD2_k127_1093746_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000002486 92.0
SHD2_k127_1100739_0 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000000007054 219.0
SHD2_k127_1100739_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000002463 216.0
SHD2_k127_1100739_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K00657 - 2.3.1.57 0.00000004781 54.0
SHD2_k127_1107916_0 DNA methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000673 233.0
SHD2_k127_1107916_1 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000000000000000001958 175.0
SHD2_k127_1107916_2 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000000008042 154.0
SHD2_k127_1107916_3 - - - - 0.0000000000000000000000000000000000000002665 160.0
SHD2_k127_1107916_4 PFAM peptidase - - - 0.00000000000000000000000000001042 129.0
SHD2_k127_1115063_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 342.0
SHD2_k127_1115063_1 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000001709 171.0
SHD2_k127_1115063_2 PFAM AMP-dependent synthetase and ligase - - - 0.0001367 53.0
SHD2_k127_1115588_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 449.0
SHD2_k127_1115588_1 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009579 355.0
SHD2_k127_1115588_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 311.0
SHD2_k127_1115588_3 Fumarase C-terminus K01676,K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 299.0
SHD2_k127_1115588_4 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000007464 112.0
SHD2_k127_1128510_0 Serine carboxypeptidase - - - 2.562e-200 634.0
SHD2_k127_1128510_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001424 283.0
SHD2_k127_1128510_10 Peptidase family S58 K01266 - 3.4.11.19 0.000004617 50.0
SHD2_k127_1128510_2 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000004366 234.0
SHD2_k127_1128510_3 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000001275 155.0
SHD2_k127_1128510_4 TIGRFAM proline-specific peptidases, Bacillus coagulans-type subfamily K01259 - 3.4.11.5 0.0000000000000000000000000000000002295 143.0
SHD2_k127_1128510_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000002853 123.0
SHD2_k127_1128510_6 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000006227 111.0
SHD2_k127_1128510_7 Anti-sigma-K factor rskA - - - 0.00000000000000000000005142 108.0
SHD2_k127_1128510_8 - - - - 0.000000000000000004718 90.0
SHD2_k127_1128510_9 - - - - 0.00000006961 61.0
SHD2_k127_1132525_0 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 407.0
SHD2_k127_1132525_1 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 388.0
SHD2_k127_1132525_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 372.0
SHD2_k127_1132525_3 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000001901 164.0
SHD2_k127_1133894_0 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000001041 241.0
SHD2_k127_1133894_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000009387 153.0
SHD2_k127_1133894_2 Cyclic-di-AMP receptor - - - 0.0000000000000000000000000000006673 124.0
SHD2_k127_1133894_3 Cyclic-di-AMP receptor - - - 0.00000000000000004062 83.0
SHD2_k127_1133894_4 Involved in the tonB-independent uptake of proteins - - - 0.00000000001147 77.0
SHD2_k127_1138367_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 476.0
SHD2_k127_1138367_1 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 411.0
SHD2_k127_1138367_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 349.0
SHD2_k127_1138367_3 - - - - 0.00000000000000000000000000000000000007302 145.0
SHD2_k127_1138367_4 - - - - 0.000000000000000000000000009198 112.0
SHD2_k127_1148827_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.104e-201 635.0
SHD2_k127_1148827_1 Peptidase family M41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 346.0
SHD2_k127_1148827_2 succinate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004417 291.0
SHD2_k127_1148827_3 - - - - 0.00000000000000000000000000000000000000000000000000000002426 203.0
SHD2_k127_1148827_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000001992 164.0
SHD2_k127_1148827_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000004685 113.0
SHD2_k127_1148827_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00005141 54.0
SHD2_k127_1150431_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 291.0
SHD2_k127_1150431_1 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001449 281.0
SHD2_k127_1150431_2 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000004997 236.0
SHD2_k127_1150431_3 Cna protein B-type domain - - - 0.0000000000000002632 93.0
SHD2_k127_1150431_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000004342 83.0
SHD2_k127_1150431_5 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000001112 78.0
SHD2_k127_1150431_6 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000009838 68.0
SHD2_k127_1157230_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 2.245e-278 866.0
SHD2_k127_1157230_1 His Kinase A (phosphoacceptor - - - 9.128e-198 655.0
SHD2_k127_1157230_2 Cellulose biosynthesis protein BcsQ K02282 - - 0.000000000000000000000000000002321 125.0
SHD2_k127_1157230_3 methyltransferase - - - 0.000000000000002484 78.0
SHD2_k127_1157230_4 PFAM regulatory protein LuxR - - - 0.0000008475 53.0
SHD2_k127_1162571_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 7.428e-213 669.0
SHD2_k127_1162571_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 469.0
SHD2_k127_1162571_2 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000003081 267.0
SHD2_k127_1162571_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000005031 194.0
SHD2_k127_1162571_4 antisigma factor binding K04749 - - 0.0004013 49.0
SHD2_k127_1162672_0 AAA ATPase domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 586.0
SHD2_k127_1162672_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 456.0
SHD2_k127_1162672_2 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000006617 236.0
SHD2_k127_1162672_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000003586 194.0
SHD2_k127_1162672_4 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000001678 173.0
SHD2_k127_1162672_5 Cysteine-rich secretory protein family - - - 0.0000000000000000000003691 108.0
SHD2_k127_1165188_0 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 488.0
SHD2_k127_1165188_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 394.0
SHD2_k127_1165188_2 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 387.0
SHD2_k127_1165188_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 356.0
SHD2_k127_1165188_4 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 295.0
SHD2_k127_1165188_5 Polysaccharide biosynthesis protein K01784,K02473,K03274 - 5.1.3.2,5.1.3.20,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001559 281.0
SHD2_k127_1165188_6 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000000001057 186.0
SHD2_k127_1165188_7 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000006556 162.0
SHD2_k127_1198062_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 345.0
SHD2_k127_1198062_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000001193 216.0
SHD2_k127_1198062_2 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000002263 209.0
SHD2_k127_1198062_3 PFAM regulatory protein GntR HTH - - - 0.000000000000000000000000000009669 128.0
SHD2_k127_120221_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 327.0
SHD2_k127_120221_1 TIGRFAM DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000004243 243.0
SHD2_k127_120221_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000001628 188.0
SHD2_k127_120221_4 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000001365 129.0
SHD2_k127_120221_5 - - - - 0.000000000000000000000000008666 116.0
SHD2_k127_120221_6 - - - - 0.00000000000000000000000003994 116.0
SHD2_k127_120221_7 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.00000000000001605 76.0
SHD2_k127_1202861_0 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 574.0
SHD2_k127_1202861_1 PFAM peptidase M4 thermolysin K08603 - 3.4.24.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 480.0
SHD2_k127_1202861_2 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 421.0
SHD2_k127_1202861_3 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 344.0
SHD2_k127_1202861_4 CYTH domain K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000000000426 177.0
SHD2_k127_1202861_5 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.00000000000000000000000000000576 125.0
SHD2_k127_1202861_6 - - - - 0.00000004911 59.0
SHD2_k127_1218897_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 314.0
SHD2_k127_1218897_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001072 248.0
SHD2_k127_1218897_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000003555 216.0
SHD2_k127_1218897_3 methyltransferase activity K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000001125 205.0
SHD2_k127_1218897_4 stage II sporulation K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000003657 187.0
SHD2_k127_125859_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 488.0
SHD2_k127_125859_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 355.0
SHD2_k127_125859_2 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 310.0
SHD2_k127_125859_3 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000005163 205.0
SHD2_k127_125859_4 glyoxalase - - - 0.0000000000000000000000000000000000000000000000000002452 188.0
SHD2_k127_125859_5 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000001366 186.0
SHD2_k127_125859_6 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' K09879 - - 0.00000000000000000000000000000000000003694 156.0
SHD2_k127_125859_7 - - - - 0.0005726 51.0
SHD2_k127_1277006_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 543.0
SHD2_k127_1277006_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 501.0
SHD2_k127_1277006_2 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000005859 220.0
SHD2_k127_1277006_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000001668 209.0
SHD2_k127_1277006_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000002025 207.0
SHD2_k127_1277006_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000001459 131.0
SHD2_k127_1289961_0 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 566.0
SHD2_k127_1289961_1 diguanylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 442.0
SHD2_k127_1289961_10 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000005319 163.0
SHD2_k127_1289961_11 regulation of single-species biofilm formation K02342,K03763,K13573 - 2.7.7.7 0.000000000000000000000000000000000002567 148.0
SHD2_k127_1289961_12 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000003545 134.0
SHD2_k127_1289961_13 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.0000000000000000002429 96.0
SHD2_k127_1289961_14 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000005663 93.0
SHD2_k127_1289961_15 PFAM NHL repeat containing protein - - - 0.0000000000000001545 91.0
SHD2_k127_1289961_16 Diguanylate cyclase - - - 0.00000000006179 75.0
SHD2_k127_1289961_17 Protein of unknown function (DUF3592) - - - 0.000000002405 64.0
SHD2_k127_1289961_18 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.000000002554 60.0
SHD2_k127_1289961_2 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 380.0
SHD2_k127_1289961_3 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 346.0
SHD2_k127_1289961_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000005782 261.0
SHD2_k127_1289961_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001499 259.0
SHD2_k127_1289961_6 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000008159 264.0
SHD2_k127_1289961_7 Adenosine/AMP deaminase K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000001984 215.0
SHD2_k127_1289961_8 lipolytic protein G-D-S-L family K01179,K01183 - 3.2.1.14,3.2.1.4 0.00000000000000000000000000000000000000000000000000000001815 205.0
SHD2_k127_1289961_9 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000714 175.0
SHD2_k127_129193_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.373e-273 879.0
SHD2_k127_129193_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.074e-267 829.0
SHD2_k127_129193_10 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000001069 199.0
SHD2_k127_129193_11 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000000000001118 182.0
SHD2_k127_129193_12 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000000000000000000002485 167.0
SHD2_k127_129193_13 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000003682 153.0
SHD2_k127_129193_14 DNA-binding transcription factor activity K02470,K03833 - 5.99.1.3 0.00000000000000000000000000000000004502 148.0
SHD2_k127_129193_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000001136 128.0
SHD2_k127_129193_16 TIR domain - - - 0.00000000000000000000004936 113.0
SHD2_k127_129193_17 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000005238 85.0
SHD2_k127_129193_2 (ABC) transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008791 443.0
SHD2_k127_129193_3 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 435.0
SHD2_k127_129193_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 321.0
SHD2_k127_129193_5 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 323.0
SHD2_k127_129193_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000001135 250.0
SHD2_k127_129193_7 Arginase family - - - 0.00000000000000000000000000000000000000000000000000000007082 205.0
SHD2_k127_129193_8 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000008422 207.0
SHD2_k127_129193_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000002951 194.0
SHD2_k127_1295886_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 5.585e-230 719.0
SHD2_k127_1295886_2 Domain of unknown function (DUF4203) - - - 0.00000000000001038 78.0
SHD2_k127_1295886_3 Domain of unknown function (DUF4203) - - - 0.00000000009615 69.0
SHD2_k127_1310040_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 609.0
SHD2_k127_1310040_1 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 329.0
SHD2_k127_1310040_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000001856 175.0
SHD2_k127_1334508_0 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 295.0
SHD2_k127_1334508_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000009431 253.0
SHD2_k127_1334508_2 PFAM Haloacid dehalogenase domain protein hydrolase K01101 - 3.1.3.41 0.0000000000000000000000000000000000000000000000000000000000000000001139 239.0
SHD2_k127_1334508_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000003091 117.0
SHD2_k127_1381548_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575 5.3.1.25,5.3.1.3 2.695e-308 953.0
SHD2_k127_1381548_1 carbohydrate kinase FGGY K00848 - 2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 516.0
SHD2_k127_1381548_2 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 481.0
SHD2_k127_1381548_3 Tagatose 6 phosphate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 424.0
SHD2_k127_1381548_4 Class ii aldolase K01628,K01629 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008994,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.17,4.1.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 349.0
SHD2_k127_1381548_5 PHP domain protein - - - 0.00000000000000000000000000000000000000000000004326 173.0
SHD2_k127_1381548_6 DeoR C terminal sensor domain - GO:0005975,GO:0006066,GO:0006071,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016052,GO:0019219,GO:0019222,GO:0019400,GO:0019405,GO:0019563,GO:0019751,GO:0031323,GO:0031326,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901575,GO:1901615,GO:1901616,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000002476 177.0
SHD2_k127_1381548_7 Fructose-1,6-bisphosphate aldolase, class II K01624 - 4.1.2.13 0.000000000000000000000000009486 111.0
SHD2_k127_1392224_0 Peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 413.0
SHD2_k127_1392224_1 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 348.0
SHD2_k127_1392224_2 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 338.0
SHD2_k127_1392224_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000002864 194.0
SHD2_k127_1392224_4 PFAM inositol monophosphatase - - - 0.00000000000000000000000000000000000000000000000000007498 191.0
SHD2_k127_1392224_5 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000009373 185.0
SHD2_k127_1392224_6 Haem-binding domain - - - 0.00000000000000000000000000000000000003004 148.0
SHD2_k127_1392224_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000005256 138.0
SHD2_k127_1392224_8 regulation of RNA biosynthetic process K22109,K22301 - - 0.00000000000000000000000002018 115.0
SHD2_k127_139759_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 308.0
SHD2_k127_139759_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000002211 155.0
SHD2_k127_139759_2 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.0000000000000000000000000000000000000003389 151.0
SHD2_k127_139759_3 Peptidase_C39 like family - - - 0.00001771 48.0
SHD2_k127_1405122_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000003046 146.0
SHD2_k127_1405122_1 to YegS from E. coli K07029 GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 0.00000000000004755 80.0
SHD2_k127_1419021_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 368.0
SHD2_k127_1419021_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 346.0
SHD2_k127_1419021_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 331.0
SHD2_k127_1419021_3 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 298.0
SHD2_k127_1419021_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003571 281.0
SHD2_k127_1419021_5 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001098 259.0
SHD2_k127_1419021_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009512 249.0
SHD2_k127_1419021_7 TIGRFAM phosphate ABC transporter, permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000002631 245.0
SHD2_k127_1419021_8 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000573 213.0
SHD2_k127_1419021_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000002455 186.0
SHD2_k127_1430918_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 4.77e-220 705.0
SHD2_k127_1430918_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 529.0
SHD2_k127_1430918_2 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 312.0
SHD2_k127_1430918_3 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 295.0
SHD2_k127_1430918_4 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001679 283.0
SHD2_k127_1430918_5 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000000000000000000000000000000000000000000000000000000000001768 222.0
SHD2_k127_1430918_7 Belongs to the ParA family K03609 - - 0.000000000000000000000000006167 110.0
SHD2_k127_1430918_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000001977 67.0
SHD2_k127_1441269_0 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 625.0
SHD2_k127_1441269_1 Beta-eliminating lyase - - - 0.000000000000000000000000000000000000000000000000175 179.0
SHD2_k127_1441269_2 Membrane - - - 0.0000000000000000000000000009333 126.0
SHD2_k127_1441269_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000054 76.0
SHD2_k127_1441269_4 - K03006 - 2.7.7.6 0.0008753 49.0
SHD2_k127_1473228_0 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 355.0
SHD2_k127_1473228_1 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 332.0
SHD2_k127_1473228_2 transcriptional regulator K21903 - - 0.0000000000000000000000006911 108.0
SHD2_k127_1473228_3 Lamin Tail Domain - - - 0.00000000000002073 79.0
SHD2_k127_1473228_4 Hydrolase of X-linked nucleoside diphosphate N terminal K01515 - 3.6.1.13 0.000000000001826 74.0
SHD2_k127_1473228_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000236 52.0
SHD2_k127_1476444_0 Alanine-glyoxylate amino-transferase K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 442.0
SHD2_k127_1476444_1 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 432.0
SHD2_k127_1476444_2 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001117 250.0
SHD2_k127_1476444_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000001387 209.0
SHD2_k127_1476444_4 SdpI/YhfL protein family - - - 0.000000000000000000000000000000000000000000000000007762 190.0
SHD2_k127_1476444_5 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000006487 187.0
SHD2_k127_1476444_6 Putative membrane peptidase family (DUF2324) - - - 0.0000000000000000000000000000000000000000009744 166.0
SHD2_k127_1476444_7 PFAM regulatory protein GntR HTH K07979 - - 0.00000000000000000000000000000000000001468 149.0
SHD2_k127_1476444_8 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000002712 146.0
SHD2_k127_1477696_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007672 572.0
SHD2_k127_1486050_0 Aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 463.0
SHD2_k127_1486050_1 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000001585 200.0
SHD2_k127_1486050_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000003565 172.0
SHD2_k127_1486050_3 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000001507 59.0
SHD2_k127_1486050_4 Squalene--hopene cyclase - - - 0.0001508 50.0
SHD2_k127_1493725_0 PFAM Enoyl-CoA hydratase isomerase K07516 - 1.1.1.35 1.567e-249 793.0
SHD2_k127_1493725_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 520.0
SHD2_k127_1493725_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00003002 48.0
SHD2_k127_1525611_0 Citrate lyase K11390 GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019222,GO:0022607,GO:0030656,GO:0031323,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046912,GO:0047777,GO:0050789,GO:0050794,GO:0051171,GO:0051193,GO:0051259,GO:0051260,GO:0062012,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0071840,GO:0106064,GO:1901401 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004475 280.0
SHD2_k127_1525611_1 cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000005362 233.0
SHD2_k127_1525611_2 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.000000000000000000000000000000000000000000000000000000000000006905 220.0
SHD2_k127_1525611_4 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.0000000000000001154 86.0
SHD2_k127_1543858_0 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 426.0
SHD2_k127_1543858_1 response regulator - - - 0.0000000000000000000000000000008181 125.0
SHD2_k127_1543858_2 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.000000000000000000009167 95.0
SHD2_k127_1543858_3 methyltransferase activity - - - 0.00000000004185 66.0
SHD2_k127_1543858_4 Transposase DDE domain - - - 0.000000007512 61.0
SHD2_k127_1543858_5 Phytoene synthase K21678 - 2.5.1.103 0.000001225 60.0
SHD2_k127_1559375_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 417.0
SHD2_k127_1559375_1 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000007305 184.0
SHD2_k127_1559375_2 - - - - 0.00000000000000000000000000000000000000000000002376 183.0
SHD2_k127_1559375_3 Belongs to the MenA family. Type 1 subfamily K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.00000000009717 64.0
SHD2_k127_1562834_0 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009898 280.0
SHD2_k127_1562834_1 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002423 266.0
SHD2_k127_1562834_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000003445 121.0
SHD2_k127_1562834_3 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000126 104.0
SHD2_k127_15636_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 423.0
SHD2_k127_15636_1 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000275 245.0
SHD2_k127_15636_2 OsmC-like protein K09136 - - 0.0000000000000000000000000000000000000000000000001535 179.0
SHD2_k127_15636_3 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000001574 158.0
SHD2_k127_15636_4 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000001464 113.0
SHD2_k127_15636_5 YacP-like NYN domain K06962 - - 0.00000000000000000000000002297 121.0
SHD2_k127_15636_8 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000001547 53.0
SHD2_k127_15636_9 - - - - 0.0002321 53.0
SHD2_k127_1571467_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 438.0
SHD2_k127_1571467_2 exodeoxyribonuclease I activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004817 227.0
SHD2_k127_1571467_3 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000584 224.0
SHD2_k127_1577445_0 Domain present in PSD-95, Dlg, and ZO-1/2. K04771,K08070 - 1.3.1.74,3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 320.0
SHD2_k127_1577445_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000002503 260.0
SHD2_k127_1577445_2 Short-chain Dehydrogenase reductase - - - 0.0000000000000000000000000000009839 127.0
SHD2_k127_1577445_3 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000002047 103.0
SHD2_k127_1577445_4 NUDIX domain - - - 0.00000007387 59.0
SHD2_k127_1592538_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 2.394e-250 785.0
SHD2_k127_1592538_1 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 1.066e-201 634.0
SHD2_k127_1592538_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000002192 91.0
SHD2_k127_1592538_11 Involved in the tonB-independent uptake of proteins - - - 0.00005458 49.0
SHD2_k127_1592538_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 536.0
SHD2_k127_1592538_3 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 482.0
SHD2_k127_1592538_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 444.0
SHD2_k127_1592538_6 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 318.0
SHD2_k127_1592538_7 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009707 250.0
SHD2_k127_1592538_8 Amidohydrolase family - - - 0.000000000000000000000000000000000000005102 148.0
SHD2_k127_1592538_9 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000001494 122.0
SHD2_k127_16036_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 559.0
SHD2_k127_16036_1 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 408.0
SHD2_k127_16036_2 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 389.0
SHD2_k127_16036_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000366 217.0
SHD2_k127_16036_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000008027 74.0
SHD2_k127_16036_6 RNA binding motif protein 19 K14787 GO:0000003,GO:0000469,GO:0000478,GO:0002119,GO:0002164,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0007275,GO:0007548,GO:0008150,GO:0008152,GO:0008406,GO:0009791,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0018996,GO:0022414,GO:0022613,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0034470,GO:0034641,GO:0034660,GO:0040002,GO:0040008,GO:0040009,GO:0040010,GO:0040019,GO:0040025,GO:0042254,GO:0042303,GO:0042335,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045137,GO:0045927,GO:0045995,GO:0046483,GO:0048513,GO:0048518,GO:0048569,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0051094,GO:0051239,GO:0051240,GO:0061458,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:1901360,GO:1901363,GO:2000026 - 0.0002294 44.0
SHD2_k127_1604755_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000002916 169.0
SHD2_k127_1604755_1 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000994 83.0
SHD2_k127_1604755_2 Alpha beta hydrolase - - - 0.0000000000003391 70.0
SHD2_k127_1604755_3 TIGRFAM C_GCAxxG_C_C family protein - - - 0.000000004375 58.0
SHD2_k127_1605421_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 363.0
SHD2_k127_1605421_1 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001402 257.0
SHD2_k127_1605421_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000006296 246.0
SHD2_k127_1613982_0 histidine kinase A domain protein - - - 6.355e-222 723.0
SHD2_k127_1613982_1 Hexapeptide repeat of succinyl-transferase - - - 3.351e-199 627.0
SHD2_k127_1613982_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 456.0
SHD2_k127_1613982_3 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 417.0
SHD2_k127_1613982_4 Shikimate quinate 5-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 384.0
SHD2_k127_1613982_5 4-vinyl reductase, 4VR - - - 0.00000000000000000000000000000000000000000000000000000000003081 212.0
SHD2_k127_1613982_6 TIGRFAM small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000003495 167.0
SHD2_k127_1621531_0 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 589.0
SHD2_k127_1621531_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 485.0
SHD2_k127_1621531_10 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000006714 175.0
SHD2_k127_1621531_11 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000172 152.0
SHD2_k127_1621531_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000003007 149.0
SHD2_k127_1621531_14 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000001187 143.0
SHD2_k127_1621531_15 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000009201 131.0
SHD2_k127_1621531_2 protein histidine kinase activity K10819 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 402.0
SHD2_k127_1621531_3 PFAM response regulator receiver K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 314.0
SHD2_k127_1621531_4 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 301.0
SHD2_k127_1621531_5 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004765 243.0
SHD2_k127_1621531_6 bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006542 227.0
SHD2_k127_1621531_7 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000000004838 203.0
SHD2_k127_1621531_8 Domain of unknown function (DUF4111) - - - 0.00000000000000000000000000000000000000000000000000000004488 205.0
SHD2_k127_1621531_9 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000007072 171.0
SHD2_k127_1624743_0 PFAM VanW family protein - - - 2.068e-199 639.0
SHD2_k127_1624743_1 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 322.0
SHD2_k127_1624743_2 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000008199 187.0
SHD2_k127_1624743_3 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.000000000000000000000003274 105.0
SHD2_k127_1624743_4 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000003027 103.0
SHD2_k127_1624743_6 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0001279 52.0
SHD2_k127_1629819_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 2.855e-216 686.0
SHD2_k127_1629819_1 PFAM ABC transporter related K02049,K15555,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 608.0
SHD2_k127_1629819_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 481.0
SHD2_k127_1629819_3 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 344.0
SHD2_k127_1629819_4 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001834 289.0
SHD2_k127_1629819_5 Transcriptional regulatory protein, C terminal K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000002193 233.0
SHD2_k127_1629819_6 histidine kinase HAMP region domain protein K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000005119 220.0
SHD2_k127_1629819_7 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000003531 141.0
SHD2_k127_1629819_8 cellular response to heat K09807 - - 0.000000000000000000000005254 113.0
SHD2_k127_1629819_9 This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria K19223 - - 0.000005372 58.0
SHD2_k127_1652932_0 PFAM ABC transporter K06020 - 3.6.3.25 1.078e-258 807.0
SHD2_k127_1652932_1 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 476.0
SHD2_k127_1652932_2 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 339.0
SHD2_k127_1652932_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 300.0
SHD2_k127_1652932_4 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000001259 228.0
SHD2_k127_1652932_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000001069 178.0
SHD2_k127_1652932_6 N-Acetylmuramoyl-L-alanine amidase - - - 0.000000000000007198 83.0
SHD2_k127_1652932_7 - - - - 0.00000000000002836 85.0
SHD2_k127_1652932_8 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000000147 70.0
SHD2_k127_1682389_0 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 590.0
SHD2_k127_1682389_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 379.0
SHD2_k127_1682389_2 arylsulfatase activity K07014 - - 0.000000000000000000000533 108.0
SHD2_k127_1697403_0 Nucleotidyl transferase K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 421.0
SHD2_k127_1697403_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000002559 227.0
SHD2_k127_1697403_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000167 189.0
SHD2_k127_1726029_0 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 424.0
SHD2_k127_1726029_1 Probable transposase K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 422.0
SHD2_k127_1726029_2 major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 327.0
SHD2_k127_1726029_3 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 319.0
SHD2_k127_1726029_4 Transposase K07491 - - 0.000000000000000000000000000000000000000000000000000000000007301 209.0
SHD2_k127_1726029_5 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000001996 181.0
SHD2_k127_1726029_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000005302 159.0
SHD2_k127_1726029_7 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000000001251 96.0
SHD2_k127_1730454_0 Beta-eliminating lyase - - - 1.25e-238 753.0
SHD2_k127_1730454_1 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000517 175.0
SHD2_k127_1730454_2 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000000000206 171.0
SHD2_k127_1730454_3 Zinc-binding dehydrogenase - - - 0.0000000000000000026 85.0
SHD2_k127_1732175_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 536.0
SHD2_k127_1732175_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 405.0
SHD2_k127_1732175_10 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000000000000118 185.0
SHD2_k127_1732175_11 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000165 169.0
SHD2_k127_1732175_13 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.000000000003547 66.0
SHD2_k127_1732175_14 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000008057 58.0
SHD2_k127_1732175_2 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 343.0
SHD2_k127_1732175_3 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 339.0
SHD2_k127_1732175_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 337.0
SHD2_k127_1732175_5 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 329.0
SHD2_k127_1732175_6 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 320.0
SHD2_k127_1732175_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 329.0
SHD2_k127_1732175_8 PFAM secretion protein HlyD family protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 304.0
SHD2_k127_1732175_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000001312 205.0
SHD2_k127_1773111_0 Aldo/keto reductase family K06222 - 1.1.1.346 0.000000000000000000000000000000000000000000000000004744 191.0
SHD2_k127_1773111_1 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000004502 108.0
SHD2_k127_1773111_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000006243 95.0
SHD2_k127_1773111_3 PFAM phospholipid glycerol acyltransferase - - - 0.0005006 48.0
SHD2_k127_1784276_0 energy transducer activity K03531,K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 311.0
SHD2_k127_1784276_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000002393 95.0
SHD2_k127_1784276_2 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000006584 59.0
SHD2_k127_17982_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 455.0
SHD2_k127_17982_1 acetyltransferase - - - 0.000000000000000003362 89.0
SHD2_k127_183136_0 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 566.0
SHD2_k127_183136_1 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 551.0
SHD2_k127_183136_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 545.0
SHD2_k127_183136_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 505.0
SHD2_k127_183136_4 Extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 426.0
SHD2_k127_183136_5 ABC-type spermidine putrescine transport system, permease component I K02054,K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 342.0
SHD2_k127_183136_6 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001787 286.0
SHD2_k127_183136_7 sequence-specific DNA binding K03718,K03719 - - 0.000000000000000000000000000000000000000003212 159.0
SHD2_k127_183136_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000001528 64.0
SHD2_k127_1839235_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 336.0
SHD2_k127_1839235_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000001929 235.0
SHD2_k127_1860061_0 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 417.0
SHD2_k127_1860061_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 333.0
SHD2_k127_1860061_2 Glyoxalase-like domain K07032 - - 0.0000000000000000000000000000000000000000000000000000576 191.0
SHD2_k127_1860061_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000002288 174.0
SHD2_k127_18716_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 0.0 1189.0
SHD2_k127_18716_1 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 5.139e-240 749.0
SHD2_k127_18716_10 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000009448 100.0
SHD2_k127_18716_2 PhoQ Sensor - - - 1.425e-216 697.0
SHD2_k127_18716_3 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 593.0
SHD2_k127_18716_4 phosphorelay signal transduction system - GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 311.0
SHD2_k127_18716_5 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001128 251.0
SHD2_k127_18716_6 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000007623 239.0
SHD2_k127_18716_7 Phosphinothricin acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000002348 190.0
SHD2_k127_18716_8 LysE type translocator - - - 0.00000000000000000000000000000000000000000008262 167.0
SHD2_k127_18716_9 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000007326 126.0
SHD2_k127_188919_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 621.0
SHD2_k127_188919_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 396.0
SHD2_k127_188919_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000003995 252.0
SHD2_k127_189832_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009488 274.0
SHD2_k127_189832_1 Trypsin-like peptidase domain K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000002574 268.0
SHD2_k127_189832_10 Ribosomal RNA adenine dimethylase - - - 0.00009106 46.0
SHD2_k127_189832_2 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001653 242.0
SHD2_k127_189832_3 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000001835 196.0
SHD2_k127_189832_4 - - - - 0.0000000000000000000000000000000000000000003343 162.0
SHD2_k127_189832_5 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000946 132.0
SHD2_k127_189832_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000008954 128.0
SHD2_k127_189832_7 F420H(2)-dependent quinone reductase - GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363 - 0.0000000000000000000000000000586 120.0
SHD2_k127_189832_8 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000000000000000000002409 120.0
SHD2_k127_189832_9 pyridoxamine 5'-phosphate K05558,K07005 - - 0.00000008825 55.0
SHD2_k127_1913236_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 586.0
SHD2_k127_1913236_1 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 382.0
SHD2_k127_1913236_2 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003868 278.0
SHD2_k127_1913236_3 PFAM Maf family protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000003403 228.0
SHD2_k127_1913236_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000001248 224.0
SHD2_k127_1913236_5 HIT family hydrolase K02503 - - 0.000000000006395 70.0
SHD2_k127_1985577_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 7.825e-227 708.0
SHD2_k127_1985577_1 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 426.0
SHD2_k127_1985577_2 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 389.0
SHD2_k127_1985577_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 369.0
SHD2_k127_1985577_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 369.0
SHD2_k127_1985577_5 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006288 244.0
SHD2_k127_1985577_6 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000004919 155.0
SHD2_k127_1985577_7 23S rRNA-intervening sequence protein - - - 0.000000000000000000000171 101.0
SHD2_k127_1985577_8 PFAM phosphate transporter K03306 - - 0.00000000000000000001698 91.0
SHD2_k127_2010133_0 Domain of unknown function (DUF4157) - - - 0.00000000000000000000496 107.0
SHD2_k127_2033349_0 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002874 250.0
SHD2_k127_2033349_1 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000002672 250.0
SHD2_k127_2033349_2 PFAM aminotransferase class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000001797 238.0
SHD2_k127_2033349_3 Predicted membrane protein (DUF2127) - - - 0.000000000000000000000000000000002799 136.0
SHD2_k127_2033349_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000006435 106.0
SHD2_k127_2033349_5 Belongs to the bacterial histone-like protein family - - - 0.00000000000000000000006367 102.0
SHD2_k127_2033349_6 PFAM Alcohol dehydrogenase GroES-like - - - 0.000007822 48.0
SHD2_k127_2050601_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 516.0
SHD2_k127_2050601_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 451.0
SHD2_k127_2050601_2 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002576 266.0
SHD2_k127_2050601_3 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000003026 196.0
SHD2_k127_207339_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 441.0
SHD2_k127_207339_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 387.0
SHD2_k127_207339_2 anaphase-promoting complex binding K07491 - - 0.0000000000000000000002247 105.0
SHD2_k127_207339_3 - - - - 0.00003862 53.0
SHD2_k127_2115777_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 505.0
SHD2_k127_2115777_1 Malate synthase K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 479.0
SHD2_k127_2115777_10 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.00000000000000000000000000000003988 139.0
SHD2_k127_2115777_11 DinB superfamily - - - 0.000000000000000000000000000001257 130.0
SHD2_k127_2115777_12 Two component regulator propeller - - - 0.000000000000000000000000000003783 139.0
SHD2_k127_2115777_13 Histidine kinase K07678,K10909 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 0.00000000000000000000000001174 128.0
SHD2_k127_2115777_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000003979 110.0
SHD2_k127_2115777_15 Domain of unknown function (DUF4342) - - - 0.00000000000000001497 85.0
SHD2_k127_2115777_16 - - - - 0.0000000000000001633 85.0
SHD2_k127_2115777_17 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000005485 61.0
SHD2_k127_2115777_18 PFAM Glycoside hydrolase, family 13 - - - 0.000000004152 61.0
SHD2_k127_2115777_2 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 479.0
SHD2_k127_2115777_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 448.0
SHD2_k127_2115777_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 437.0
SHD2_k127_2115777_5 histidinol dehydrogenase activity K00013,K14152 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009314,GO:0009411,GO:0009416,GO:0009507,GO:0009532,GO:0009536,GO:0009555,GO:0009570,GO:0009628,GO:0009987,GO:0016053,GO:0016462,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030145,GO:0032501,GO:0032502,GO:0034641,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0048229,GO:0048856,GO:0050896,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 422.0
SHD2_k127_2115777_6 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000009697 260.0
SHD2_k127_2115777_7 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000004142 226.0
SHD2_k127_2115777_8 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000003008 174.0
SHD2_k127_2115777_9 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000001428 170.0
SHD2_k127_2135860_0 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 7.706e-265 837.0
SHD2_k127_2135860_1 Periplasmic binding protein domain K10543,K10546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 419.0
SHD2_k127_2135860_2 Sugar kinase of the NBD HSP70 family, may containing an N-terminal HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 325.0
SHD2_k127_2135860_3 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 0.000000000000000000000000000000000000000000000000000000009684 199.0
SHD2_k127_2161483_0 Dehydrogenase E1 component K00615 - 2.2.1.1 5.774e-312 974.0
SHD2_k127_2161483_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 562.0
SHD2_k127_2161483_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000147 70.0
SHD2_k127_2161483_12 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00001512 48.0
SHD2_k127_2161483_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 541.0
SHD2_k127_2161483_3 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 531.0
SHD2_k127_2161483_4 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 482.0
SHD2_k127_2161483_5 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 474.0
SHD2_k127_2161483_6 Catalytic domain of components of various dehydrogenase complexes K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 402.0
SHD2_k127_2161483_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004935 167.0
SHD2_k127_2161483_8 - - - - 0.000000000000000000000000000000003708 131.0
SHD2_k127_2168325_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 497.0
SHD2_k127_2168325_1 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 385.0
SHD2_k127_2168325_10 reversible hydration of carbon dioxide - - - 0.00000272 54.0
SHD2_k127_2168325_2 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 370.0
SHD2_k127_2168325_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 342.0
SHD2_k127_2168325_4 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001158 262.0
SHD2_k127_2168325_5 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000009111 182.0
SHD2_k127_2168325_6 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000008755 171.0
SHD2_k127_2168325_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000004201 150.0
SHD2_k127_2168325_8 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000005362 87.0
SHD2_k127_2168325_9 response regulator, receiver K07814,K13815 - - 0.00000000000004525 77.0
SHD2_k127_2170834_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 9.664e-237 741.0
SHD2_k127_2170834_1 Dehydrogenase K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 398.0
SHD2_k127_2170834_2 Dehydrogenase E1 component K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 397.0
SHD2_k127_2170834_3 Sugar ABC transporter permease K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 376.0
SHD2_k127_2170834_4 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 357.0
SHD2_k127_2170834_5 Ribose ABC transporter substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002309 267.0
SHD2_k127_2170834_6 Xylose isomerase-like TIM barrel K03079 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016857,GO:0019752,GO:0019852,GO:0034015,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051186,GO:0071704 5.1.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000001134 268.0
SHD2_k127_2170834_7 PFAM Class II aldolase adducin K03077 - 5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003773 255.0
SHD2_k127_2170834_8 Transcriptional regulator, contains sigma factor-related N-terminal domain K11531 - - 0.0000000000000000000000000000000000000000000000000000000000000000001214 241.0
SHD2_k127_2170834_9 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000003691 192.0
SHD2_k127_2190569_0 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 517.0
SHD2_k127_2190569_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 420.0
SHD2_k127_2190569_2 aminopeptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 411.0
SHD2_k127_2190569_3 WD40 repeat, subgroup - - - 0.0000000000000000000000000000000000000000000000000000000000000005755 227.0
SHD2_k127_2190569_4 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000001411 224.0
SHD2_k127_2190569_5 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000007975 220.0
SHD2_k127_2190569_6 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000133 218.0
SHD2_k127_2190569_7 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000004361 132.0
SHD2_k127_2190569_8 PFAM NHL repeat containing protein - - - 0.0000000006881 68.0
SHD2_k127_2193913_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 446.0
SHD2_k127_2193913_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 392.0
SHD2_k127_2193913_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 325.0
SHD2_k127_2193913_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 312.0
SHD2_k127_2193913_4 Iron-sulfur cluster-binding domain K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 296.0
SHD2_k127_2193913_5 peroxidase activity K09162 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114 1.13.11.49 0.000000000000000000000000000000000000000000000000000000001991 207.0
SHD2_k127_2205071_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 453.0
SHD2_k127_2205071_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 315.0
SHD2_k127_2205071_2 DegV family - - - 0.000000000000000000000000000000000000000000000003774 183.0
SHD2_k127_2205071_3 Protein of unknown function (DUF2089) - - - 0.000000000000000000000000000000000001644 141.0
SHD2_k127_2205071_4 - - - - 0.00000000000000000000000000000000475 132.0
SHD2_k127_2205071_6 - - - - 0.0000000000003906 81.0
SHD2_k127_2208329_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 524.0
SHD2_k127_2208329_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 408.0
SHD2_k127_2208329_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000002305 155.0
SHD2_k127_2208329_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 387.0
SHD2_k127_2208329_3 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 392.0
SHD2_k127_2208329_4 periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 312.0
SHD2_k127_2208329_5 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000004904 260.0
SHD2_k127_2208329_6 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000647 256.0
SHD2_k127_2208329_7 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000037 253.0
SHD2_k127_2208329_8 PFAM cobalbumin biosynthesis protein K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000001179 165.0
SHD2_k127_2208329_9 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000003243 164.0
SHD2_k127_2214779_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 459.0
SHD2_k127_2214779_1 PFAM Glycosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 335.0
SHD2_k127_2214779_2 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000002164 250.0
SHD2_k127_2214779_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000008415 156.0
SHD2_k127_2214779_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000001112 152.0
SHD2_k127_2214779_5 Domain of unknown function (DUF1905) - - - 0.0000000000000000000000000000000000001137 145.0
SHD2_k127_2215579_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 343.0
SHD2_k127_2215579_1 Glycoside hydrolase family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 311.0
SHD2_k127_2215579_2 methyltransferase K18846 - 2.1.1.180 0.000000000000000001455 94.0
SHD2_k127_2215579_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000085 65.0
SHD2_k127_2215579_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0002535 50.0
SHD2_k127_2234703_0 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 422.0
SHD2_k127_2234703_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 365.0
SHD2_k127_2234703_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - 0.0000000000000000000000000000005166 126.0
SHD2_k127_2234703_3 - - - - 0.000000000000000002641 88.0
SHD2_k127_2234703_4 photosynthesis - - - 0.000001305 61.0
SHD2_k127_2241953_0 Hsp70 protein K04046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001189 295.0
SHD2_k127_2241953_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000001106 226.0
SHD2_k127_2241953_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000181 170.0
SHD2_k127_2241953_3 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000006967 132.0
SHD2_k127_2241953_4 Signal transduction histidine kinase - - - 0.000004012 60.0
SHD2_k127_2251442_0 Tetratricopeptide repeat - - - 3.518e-223 717.0
SHD2_k127_2251442_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000003383 156.0
SHD2_k127_2251442_2 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 0.0003087 50.0
SHD2_k127_2265993_0 Aminotransferase K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 484.0
SHD2_k127_2265993_1 Aldo/keto reductase family K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 371.0
SHD2_k127_2265993_2 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 360.0
SHD2_k127_2265993_3 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000007373 139.0
SHD2_k127_2265993_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000003769 129.0
SHD2_k127_2265993_5 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000005608 110.0
SHD2_k127_2287376_0 Domain of unknown function (DUF4129) - - - 0.00000001018 67.0
SHD2_k127_2287376_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00004886 53.0
SHD2_k127_2301364_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 8.951e-261 814.0
SHD2_k127_2301364_1 PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 554.0
SHD2_k127_2301364_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 539.0
SHD2_k127_2301364_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 471.0
SHD2_k127_2301364_4 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 326.0
SHD2_k127_2301364_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001828 280.0
SHD2_k127_2301364_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000001053 151.0
SHD2_k127_2301364_7 CoA carboxylase activity K01615,K01965,K02160,K17490 - 2.1.3.1,4.1.1.70,6.4.1.3 0.00000000000000000003639 95.0
SHD2_k127_2311748_0 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 301.0
SHD2_k127_2311748_1 PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003729 287.0
SHD2_k127_2311748_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000009235 175.0
SHD2_k127_2311748_3 Protein of unknown function (DUF4230) - - - 0.0000000000000000000000000000000000286 141.0
SHD2_k127_2311748_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000005899 149.0
SHD2_k127_2315115_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.844e-252 790.0
SHD2_k127_2315115_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.963e-216 679.0
SHD2_k127_2315115_2 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 379.0
SHD2_k127_2315115_3 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 341.0
SHD2_k127_2315115_4 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 292.0
SHD2_k127_2315115_5 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001266 278.0
SHD2_k127_2315115_6 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000004494 221.0
SHD2_k127_2315115_7 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000002304 131.0
SHD2_k127_2315115_8 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 0.000000000000000001756 95.0
SHD2_k127_2315115_9 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.000000000000000004837 86.0
SHD2_k127_2354869_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.217e-290 901.0
SHD2_k127_2354869_1 Cellulose 1,4-beta-cellobiosidase - - - 0.000000000000003535 89.0
SHD2_k127_2354869_2 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.000000002229 61.0
SHD2_k127_2354869_3 Putative Flp pilus-assembly TadE/G-like - - - 0.000001623 60.0
SHD2_k127_2354869_4 TadE-like protein - - - 0.00001739 54.0
SHD2_k127_2359650_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000007859 243.0
SHD2_k127_2359650_1 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000004757 213.0
SHD2_k127_2359650_2 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000000000000000000000000000000000001429 211.0
SHD2_k127_2359650_3 Protein of unknown function (DUF402) K07586 - - 0.0000000000000000000000000000000004259 136.0
SHD2_k127_2391911_0 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 323.0
SHD2_k127_2391911_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000002391 233.0
SHD2_k127_2391911_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000009507 173.0
SHD2_k127_2391911_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000005581 119.0
SHD2_k127_2391911_4 PFAM conserved K07027 - - 0.000002219 50.0
SHD2_k127_2401737_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1569.0
SHD2_k127_2401737_1 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004494 236.0
SHD2_k127_2401737_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000000003993 208.0
SHD2_k127_2401737_3 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.000000000000000000000000000000000000000000003097 173.0
SHD2_k127_2401737_4 acetyltransferase K03823 - 2.3.1.183 0.00000000000000000000000000000000002088 141.0
SHD2_k127_2401737_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000001548 121.0
SHD2_k127_2401737_6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000004638 107.0
SHD2_k127_2401737_7 - - - - 0.0000000000000000123 86.0
SHD2_k127_2401738_0 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 501.0
SHD2_k127_2404467_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.407e-273 863.0
SHD2_k127_2404467_1 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 452.0
SHD2_k127_2404467_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 385.0
SHD2_k127_2404467_3 Dehydrogenase reductase SDR family member - - - 0.00000000000000000000000000000000000000000000001337 181.0
SHD2_k127_2404467_4 bis(5'-adenosyl)-triphosphatase activity - - - 0.000000000000000000000000002472 115.0
SHD2_k127_2404467_5 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000001799 112.0
SHD2_k127_2404467_6 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000003253 81.0
SHD2_k127_2407871_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 602.0
SHD2_k127_2407871_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 289.0
SHD2_k127_2407871_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000001358 216.0
SHD2_k127_2407871_3 enterobactin catabolic process K07214 - - 0.0000000000000000000000000000000000000000000000472 184.0
SHD2_k127_2407871_5 Nuclease-related domain - - - 0.0008318 51.0
SHD2_k127_2418223_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 572.0
SHD2_k127_2418223_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 540.0
SHD2_k127_2418223_10 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000003612 172.0
SHD2_k127_2418223_11 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000004905 157.0
SHD2_k127_2418223_12 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000004814 85.0
SHD2_k127_2418223_13 His Kinase A (phosphoacceptor) domain - - - 0.000000000007667 77.0
SHD2_k127_2418223_14 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00000000007652 72.0
SHD2_k127_2418223_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 558.0
SHD2_k127_2418223_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 502.0
SHD2_k127_2418223_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 471.0
SHD2_k127_2418223_5 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 450.0
SHD2_k127_2418223_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 436.0
SHD2_k127_2418223_7 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 413.0
SHD2_k127_2418223_8 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 372.0
SHD2_k127_2418223_9 ABC-type dipeptide oligopeptide nickel transport K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 297.0
SHD2_k127_2419833_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 5.17e-320 994.0
SHD2_k127_2419833_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 8.191e-279 871.0
SHD2_k127_2419833_10 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 325.0
SHD2_k127_2419833_11 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004252 247.0
SHD2_k127_2419833_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000007829 181.0
SHD2_k127_2419833_13 Belongs to the bacterial solute-binding protein 3 family K02030 - - 0.00000000000000000000000000000000000008785 155.0
SHD2_k127_2419833_14 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000005603 151.0
SHD2_k127_2419833_15 - - - - 0.0003415 46.0
SHD2_k127_2419833_2 Belongs to the glycosyl hydrolase 43 family - - - 5.726e-223 701.0
SHD2_k127_2419833_3 Fibronectin type III-like domain K05349 - 3.2.1.21 5.899e-200 633.0
SHD2_k127_2419833_4 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 499.0
SHD2_k127_2419833_5 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 496.0
SHD2_k127_2419833_6 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 477.0
SHD2_k127_2419833_7 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 424.0
SHD2_k127_2419833_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 405.0
SHD2_k127_2419833_9 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 352.0
SHD2_k127_2432003_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 339.0
SHD2_k127_2432003_1 L-asparaginase II K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 323.0
SHD2_k127_2432003_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 321.0
SHD2_k127_2432003_3 PFAM Translin K07477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004183 246.0
SHD2_k127_2432003_4 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.000000000000000000000000000001705 126.0
SHD2_k127_2432003_5 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.000000000000001277 81.0
SHD2_k127_2432003_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000005543 51.0
SHD2_k127_2459829_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 446.0
SHD2_k127_2459829_1 Squalene--hopene cyclase K17811 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576 5.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 439.0
SHD2_k127_2459829_10 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000008095 76.0
SHD2_k127_2459829_11 Lipopolysaccharide biosynthesis protein - - - 0.00000000002859 74.0
SHD2_k127_2459829_12 response regulator K11443 - - 0.0000002805 57.0
SHD2_k127_2459829_13 Pfam Aminotransferase class I and II K00639 - 2.3.1.29 0.00005845 55.0
SHD2_k127_2459829_2 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 335.0
SHD2_k127_2459829_3 transferase activity, transferring alkyl or aryl (other than methyl) groups K15911,K22313 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016101,GO:0016102,GO:0016114,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0035440,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0075136,GO:1901576 3.1.7.12,3.1.7.8,3.1.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005316 277.0
SHD2_k127_2459829_4 PFAM YibE F-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000007681 248.0
SHD2_k127_2459829_5 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000001306 199.0
SHD2_k127_2459829_6 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000008122 207.0
SHD2_k127_2459829_7 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000001925 190.0
SHD2_k127_2459829_8 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000001764 154.0
SHD2_k127_2459829_9 ATPases associated with a variety of cellular activities K16787 - - 0.00000000000000000000000000001888 120.0
SHD2_k127_25043_0 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 299.0
SHD2_k127_25043_1 ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004312 265.0
SHD2_k127_25043_2 TIGRFAM uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000001846 206.0
SHD2_k127_25043_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000643 99.0
SHD2_k127_25043_4 Helix-turn-helix XRE-family like proteins K15256 - - 0.0000000000000000003271 89.0
SHD2_k127_2510133_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.00000000000000000000000000002424 117.0
SHD2_k127_2510133_1 Transcriptional regulator - - - 0.0000000000000000000000000002593 117.0
SHD2_k127_2510133_2 alcohol dehydrogenase - - - 0.000000002395 68.0
SHD2_k127_2510133_3 lipolytic protein G-D-S-L family - - - 0.000828 50.0
SHD2_k127_2520413_0 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 411.0
SHD2_k127_2520413_1 transferase activity, transferring acyl groups K03824 - - 0.0000000000000000000000000000000000000000000000000000000000000003226 224.0
SHD2_k127_2520413_2 Protein of unknown function (DUF3298) - - - 0.00000000000000007339 91.0
SHD2_k127_2520413_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000003165 62.0
SHD2_k127_2640594_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 482.0
SHD2_k127_2640594_1 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 407.0
SHD2_k127_2640594_10 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000006203 150.0
SHD2_k127_2640594_11 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000002249 137.0
SHD2_k127_2640594_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000007897 127.0
SHD2_k127_2640594_13 Response regulator receiver K11443 - - 0.0000000000000000000009446 102.0
SHD2_k127_2640594_2 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 309.0
SHD2_k127_2640594_3 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002132 296.0
SHD2_k127_2640594_4 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003765 254.0
SHD2_k127_2640594_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000003972 248.0
SHD2_k127_2640594_6 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000005057 244.0
SHD2_k127_2640594_7 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000209 213.0
SHD2_k127_2640594_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000006619 193.0
SHD2_k127_2640594_9 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000002805 178.0
SHD2_k127_2692040_0 Beta-Casp domain K07576 - - 1.6e-200 633.0
SHD2_k127_2692040_1 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 423.0
SHD2_k127_2692040_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 433.0
SHD2_k127_2692040_3 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 316.0
SHD2_k127_2692040_4 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000001009 252.0
SHD2_k127_2692040_5 acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000001219 140.0
SHD2_k127_2692040_6 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000001132 90.0
SHD2_k127_2699413_0 Molydopterin dinucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 425.0
SHD2_k127_2699413_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 382.0
SHD2_k127_2699413_2 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 321.0
SHD2_k127_2701249_0 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009565 299.0
SHD2_k127_2701249_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000006442 150.0
SHD2_k127_270291_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 485.0
SHD2_k127_270291_1 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 302.0
SHD2_k127_270291_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000002379 232.0
SHD2_k127_270291_3 23S rRNA-intervening sequence protein - - - 0.0000000000000000000002188 102.0
SHD2_k127_270291_4 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000189 89.0
SHD2_k127_270291_5 - - - - 0.0000000000005787 73.0
SHD2_k127_2709790_0 uridine kinase K00876 - 2.7.1.48 4.228e-223 705.0
SHD2_k127_2709790_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K02805 GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576 2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 580.0
SHD2_k127_2709790_10 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00105,K00111 - 1.1.3.21,1.1.5.3 0.000000000000000000000000003172 115.0
SHD2_k127_2709790_2 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 405.0
SHD2_k127_2709790_3 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 359.0
SHD2_k127_2709790_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 346.0
SHD2_k127_2709790_5 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 307.0
SHD2_k127_2709790_6 trans-aconitate 2-methyltransferase activity K02169 GO:0002682,GO:0002683,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046467,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000251 235.0
SHD2_k127_2709790_7 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000000002542 211.0
SHD2_k127_2709790_8 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.0000000000000000000000000000000001777 143.0
SHD2_k127_2709790_9 VIT family - - - 0.000000000000000000000000000001148 131.0
SHD2_k127_2715041_0 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 303.0
SHD2_k127_2715041_1 TIGRFAM metal dependent phophohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 291.0
SHD2_k127_2715041_3 Endonuclease containing a URI domain K07461 - - 0.00000000000000000000000000000005729 126.0
SHD2_k127_2715041_4 - - - - 0.000000000000006982 76.0
SHD2_k127_2735850_0 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 318.0
SHD2_k127_2735850_1 PFAM inositol monophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002713 262.0
SHD2_k127_2735850_2 COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000007703 226.0
SHD2_k127_2735850_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000128 197.0
SHD2_k127_2735850_4 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000001506 184.0
SHD2_k127_2735850_5 MazG-like family - - - 0.000000000000000000000000000000002942 132.0
SHD2_k127_2735850_6 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.000000001742 62.0
SHD2_k127_2745881_0 Inosine-uridine preferring nucleoside hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 338.0
SHD2_k127_2745881_1 Domain of unknown function (DUF4111) K00984 - 2.7.7.47 0.0000000000000000000000000000000000000000000000000000000000000002382 240.0
SHD2_k127_2745881_2 GrpB protein - - - 0.00000000000000000000000000000000000000000000004439 188.0
SHD2_k127_2745881_3 Domain of unknown function (DUF348) - - - 0.0000000000000000000000000000001118 133.0
SHD2_k127_2745881_4 PFAM ABC transporter related K06158 - - 0.0000000000000000000000007279 106.0
SHD2_k127_278484_0 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 479.0
SHD2_k127_278484_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 440.0
SHD2_k127_278484_2 PFAM GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 290.0
SHD2_k127_278484_3 Molybdenum cofactor sulfurase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005235 270.0
SHD2_k127_278484_4 LysM domain - - - 0.00000000000000000000000000000000000000000000000000009927 203.0
SHD2_k127_278484_5 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000004629 165.0
SHD2_k127_278484_6 LysM domain - - - 0.00000000000000000000000000000000000000001804 169.0
SHD2_k127_278484_7 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000001319 129.0
SHD2_k127_27858_0 PFAM TPR repeat-containing protein - - - 4.103e-217 698.0
SHD2_k127_27858_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 517.0
SHD2_k127_27858_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000127 250.0
SHD2_k127_2831317_0 PFAM Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 537.0
SHD2_k127_2831317_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000003046 231.0
SHD2_k127_2831317_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000006061 194.0
SHD2_k127_2831317_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000003355 187.0
SHD2_k127_2831317_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000000675 149.0
SHD2_k127_2831317_5 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000002676 138.0
SHD2_k127_2831317_6 zinc-ribbon domain - - - 0.000000000000000000000000001503 118.0
SHD2_k127_284670_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 1.49e-198 628.0
SHD2_k127_284670_1 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 537.0
SHD2_k127_284670_10 Cytochrome c554 and c-prime - - - 0.0000000000000438 86.0
SHD2_k127_284670_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000002478 79.0
SHD2_k127_284670_12 PFAM Cyclic nucleotide-binding domain - - - 0.000000001292 65.0
SHD2_k127_284670_2 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 513.0
SHD2_k127_284670_3 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 454.0
SHD2_k127_284670_4 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 397.0
SHD2_k127_284670_5 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 336.0
SHD2_k127_284670_6 FR47-like protein - - - 0.0000000000000000000000000000000000000000005283 162.0
SHD2_k127_284670_7 - - - - 0.00000000000000000000000000000001249 134.0
SHD2_k127_284670_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000363 129.0
SHD2_k127_284670_9 - - - - 0.000000000000000000000103 105.0
SHD2_k127_2850099_0 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000002764 173.0
SHD2_k127_2884427_0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009722 445.0
SHD2_k127_2884427_1 - - - - 0.0000000000000000000000001057 112.0
SHD2_k127_2899786_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 563.0
SHD2_k127_2899786_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 538.0
SHD2_k127_2899786_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 308.0
SHD2_k127_2899786_3 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 299.0
SHD2_k127_2899786_4 Responsible for synthesis of pseudouridine from uracil K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000134 190.0
SHD2_k127_2899786_5 lactoylglutathione lyase activity - - - 0.000000000000000000000000009675 115.0
SHD2_k127_2961630_0 PFAM ThiJ PfpI domain protein K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009018 269.0
SHD2_k127_2961630_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000001554 185.0
SHD2_k127_2961630_2 WD40 domain protein beta Propeller K03641 - - 0.00000000000000000000000000007527 128.0
SHD2_k127_2961630_3 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000009184 107.0
SHD2_k127_2964489_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 3.603e-220 698.0
SHD2_k127_2964489_1 COG1063 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 387.0
SHD2_k127_2964489_2 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007702 256.0
SHD2_k127_2964489_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000002182 184.0
SHD2_k127_2964489_4 GGDEF domain - - - 0.00000000000000000000000000000000000000001078 166.0
SHD2_k127_3013909_0 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000006286 111.0
SHD2_k127_3013909_1 NmrA-like family - - - 0.000000000000000000000004918 109.0
SHD2_k127_3013909_2 NmrA-like family - - - 0.000000000608 61.0
SHD2_k127_3013909_3 - - - - 0.000000001004 71.0
SHD2_k127_3013909_4 NmrA-like family - - - 0.00005384 48.0
SHD2_k127_301755_0 Castor and Pollux, part of voltage-gated ion channel - - - 1.237e-194 627.0
SHD2_k127_301755_1 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 342.0
SHD2_k127_301755_2 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000005577 196.0
SHD2_k127_301755_3 - - - - 0.00000000002042 64.0
SHD2_k127_3036764_0 Tetratricopeptide TPR_2 repeat protein - - - 2.641e-276 893.0
SHD2_k127_3036764_1 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 544.0
SHD2_k127_3036764_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000674 249.0
SHD2_k127_3036764_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000001279 187.0
SHD2_k127_3036764_4 Methyltransferase domain - - - 0.000000000000000000005244 102.0
SHD2_k127_3042381_0 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 351.0
SHD2_k127_3042381_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 358.0
SHD2_k127_3042381_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003284 251.0
SHD2_k127_3042381_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000004611 239.0
SHD2_k127_3042381_4 PFAM Bacterial regulatory proteins, tetR family K09017 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000009081 203.0
SHD2_k127_3042381_5 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000802 148.0
SHD2_k127_3042381_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000001203 104.0
SHD2_k127_3114220_0 PFAM Transketolase central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 542.0
SHD2_k127_3114220_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 452.0
SHD2_k127_3114220_10 - - - - 0.00000000000000000000000000000004617 130.0
SHD2_k127_3114220_11 MerR, DNA binding - - - 0.00000000000000000000000003786 112.0
SHD2_k127_3114220_12 ROK family K00847 - 2.7.1.4 0.0000000000000000000000002684 107.0
SHD2_k127_3114220_13 - - - - 0.000000000000000001596 91.0
SHD2_k127_3114220_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000003299 71.0
SHD2_k127_3114220_15 Response regulator receiver K02483,K07658,K07668 - - 0.00000007152 59.0
SHD2_k127_3114220_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 343.0
SHD2_k127_3114220_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 316.0
SHD2_k127_3114220_4 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000001184 234.0
SHD2_k127_3114220_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000001982 212.0
SHD2_k127_3114220_7 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000001246 188.0
SHD2_k127_3114220_8 S-adenosyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000844 184.0
SHD2_k127_3114220_9 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000000003287 166.0
SHD2_k127_3117214_0 deoxyribonuclease IV (phage-T4-induced) activity K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 361.0
SHD2_k127_3117214_1 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 324.0
SHD2_k127_3117214_2 hydrolase (HAD superfamily) K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.00000000000000000000000000000000000000000000000000001553 196.0
SHD2_k127_3117214_3 PFAM diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000000165 146.0
SHD2_k127_3145424_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 481.0
SHD2_k127_3145424_1 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000134 140.0
SHD2_k127_3145424_2 antisigma factor binding K04749 - - 0.000000000000000002873 89.0
SHD2_k127_3148003_0 Protein of unknown function DUF115 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 349.0
SHD2_k127_3148003_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 323.0
SHD2_k127_3184636_0 ABC transporter K15738 - - 1.162e-223 707.0
SHD2_k127_3184636_1 FAD binding domain in molybdopterin dehydrogenase K03519,K12529 - 1.2.5.3 0.000000000000000002529 88.0
SHD2_k127_3185351_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 502.0
SHD2_k127_3185351_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 435.0
SHD2_k127_3185351_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 382.0
SHD2_k127_3185351_4 polysaccharide biosynthetic process K16694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 328.0
SHD2_k127_3185351_6 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000000000000000001553 221.0
SHD2_k127_3185351_7 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000004165 194.0
SHD2_k127_3193499_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1146.0
SHD2_k127_3193499_1 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 375.0
SHD2_k127_3193499_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000003507 231.0
SHD2_k127_3193499_3 Hydrolase, alpha beta fold family K00433 - 1.11.1.10 0.0000000000000000000000001487 116.0
SHD2_k127_3193499_4 rRNA binding K02879,K02888,K02890,K02899,K02967,K04074 - - 0.0000000005575 66.0
SHD2_k127_3193499_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000002296 60.0
SHD2_k127_320196_0 PHP domain protein K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 339.0
SHD2_k127_320196_1 methyltransferase activity - - - 0.0000000000000000000000000000000000211 140.0
SHD2_k127_320196_2 methyltransferase activity - - - 0.000000000001005 72.0
SHD2_k127_3209106_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 560.0
SHD2_k127_3209106_1 - - - - 0.000000000000000000000000000000000000000000000000003146 187.0
SHD2_k127_3209106_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000006439 163.0
SHD2_k127_3209106_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000001176 164.0
SHD2_k127_3209106_4 PFAM aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000074 134.0
SHD2_k127_3212796_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 557.0
SHD2_k127_3212796_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 324.0
SHD2_k127_3212796_2 transcription factor binding K11527 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 317.0
SHD2_k127_3212796_3 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006562 259.0
SHD2_k127_3212796_4 Pfam:DUF422 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009357 254.0
SHD2_k127_3212796_5 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000000000001683 252.0
SHD2_k127_3212796_6 overlaps another CDS with the same product name K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000217 246.0
SHD2_k127_3212796_7 Low molecular weight phosphatase family - - - 0.0000000000000000000000007309 109.0
SHD2_k127_3212796_8 Major Facilitator Superfamily - - - 0.00000000000000001573 90.0
SHD2_k127_3212796_9 sterol carrier protein - - - 0.000158 44.0
SHD2_k127_3213518_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 8.857e-214 686.0
SHD2_k127_3213518_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 409.0
SHD2_k127_3213518_2 PFAM aminotransferase class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 313.0
SHD2_k127_3213518_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000976 231.0
SHD2_k127_3213518_4 Blue (Type 1) copper domain protein - - - 0.0000000000000000000000000000000008248 134.0
SHD2_k127_3214365_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 599.0
SHD2_k127_3214365_1 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001468 284.0
SHD2_k127_3214365_2 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000472 81.0
SHD2_k127_3214365_3 serine threonine protein kinase K03587,K08884,K12132 - 2.7.11.1,3.4.16.4 0.0000000000004927 82.0
SHD2_k127_3235555_0 Immune inhibitor A peptidase M6 - - - 9.138e-206 660.0
SHD2_k127_3235555_1 Oxidoreductase FAD-binding domain K00523,K05784 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 306.0
SHD2_k127_3235555_10 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000002309 81.0
SHD2_k127_3235555_12 Transcriptional regulator K02529,K07506 - - 0.00001983 49.0
SHD2_k127_3235555_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 309.0
SHD2_k127_3235555_3 Oxidoreductase molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 289.0
SHD2_k127_3235555_4 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002913 268.0
SHD2_k127_3235555_5 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001027 281.0
SHD2_k127_3235555_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000008863 181.0
SHD2_k127_3235555_7 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000001086 172.0
SHD2_k127_3235555_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000001253 144.0
SHD2_k127_3235555_9 - - - - 0.000000000000000006414 87.0
SHD2_k127_3239303_0 PFAM ABC transporter related K06158 - - 1.19e-200 645.0
SHD2_k127_3239303_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 327.0
SHD2_k127_3239303_2 ATP hydrolysis coupled proton transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001129 270.0
SHD2_k127_3239303_3 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000000000001588 207.0
SHD2_k127_3239303_4 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000000005831 198.0
SHD2_k127_3239303_5 - - - - 0.000000000000000000000000000000000009123 138.0
SHD2_k127_3239303_6 - - - - 0.00000000000000000000000000000000001 138.0
SHD2_k127_3276671_0 PFAM type II secretion system protein E K02283 - - 1.958e-233 729.0
SHD2_k127_3276671_1 PFAM response regulator receiver K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 499.0
SHD2_k127_3276671_10 Flp pilus assembly protein CpaB K02279 - - 0.00000000002077 66.0
SHD2_k127_3276671_2 PFAM type II secretion system protein K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 376.0
SHD2_k127_3276671_3 PFAM type II secretion system protein K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 358.0
SHD2_k127_3276671_4 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000009995 256.0
SHD2_k127_3276671_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000000000009362 206.0
SHD2_k127_3276671_6 competence protein - - - 0.000000000000000000000000000000000000000000000000004739 190.0
SHD2_k127_3276671_7 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.000000000000000000000000004171 119.0
SHD2_k127_3276671_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.000000000000000000003071 97.0
SHD2_k127_3276671_9 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000003074 100.0
SHD2_k127_3281294_0 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 596.0
SHD2_k127_3281294_1 Transcriptional regulator K02529,K07506 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 331.0
SHD2_k127_3281294_2 Gaf domain - - - 0.0000000000000000000000000000000001331 153.0
SHD2_k127_3282900_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 535.0
SHD2_k127_3282900_1 ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 316.0
SHD2_k127_3282900_10 - - - - 0.00000000000000000000000001879 112.0
SHD2_k127_3282900_11 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000002353 109.0
SHD2_k127_3282900_2 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006306 304.0
SHD2_k127_3282900_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001439 273.0
SHD2_k127_3282900_4 Psort location Cytoplasmic, score 8.96 K19286 - 1.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000003477 269.0
SHD2_k127_3282900_5 phospholipase C K21302 - 3.1.3.64 0.0000000000000000000000000000000000000000000000000000000000000001553 250.0
SHD2_k127_3282900_6 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000003808 227.0
SHD2_k127_3282900_7 Integral membrane - - - 0.00000000000000000000000000000001496 134.0
SHD2_k127_3282900_8 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000001659 124.0
SHD2_k127_3282900_9 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000005161 120.0
SHD2_k127_3287224_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 1.615e-312 974.0
SHD2_k127_3287224_1 ferrous iron binding K06990,K15755 - - 0.00000000000000000000000000000000000000000000000000000002206 206.0
SHD2_k127_3287224_2 - - - - 0.000000000000000000000000000000000000000000000000000008342 192.0
SHD2_k127_3287224_3 S-adenosylmethionine decarboxylase - - - 0.0000000000000000000000000000000000000006377 151.0
SHD2_k127_3287224_4 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000205 131.0
SHD2_k127_330226_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.955e-253 790.0
SHD2_k127_330226_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 548.0
SHD2_k127_330226_10 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.000000000000000000000000598 108.0
SHD2_k127_330226_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 376.0
SHD2_k127_330226_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 363.0
SHD2_k127_330226_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 370.0
SHD2_k127_330226_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 331.0
SHD2_k127_330226_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 319.0
SHD2_k127_330226_7 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000006079 229.0
SHD2_k127_330226_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000001612 149.0
SHD2_k127_33079_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 459.0
SHD2_k127_33079_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 331.0
SHD2_k127_33079_2 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000000000000002334 179.0
SHD2_k127_33079_3 - - - - 0.000000000000000000000000000000388 125.0
SHD2_k127_33079_4 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000001044 117.0
SHD2_k127_33079_5 CAAX protease self-immunity K07052,K09696 - - 0.00000000000000000000000003145 117.0
SHD2_k127_3309060_0 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000004512 243.0
SHD2_k127_3309060_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000002742 189.0
SHD2_k127_3309060_2 TIR domain - - - 0.0000000000000000000000000000000000000009138 170.0
SHD2_k127_3309060_3 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.00000000000000000000000000000000417 135.0
SHD2_k127_3324216_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 526.0
SHD2_k127_3324216_1 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001036 259.0
SHD2_k127_3324216_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000166 208.0
SHD2_k127_3324216_3 chitin catabolic process K01183,K03933,K13381 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.14,3.2.1.17 0.0000000000000000000000000000000000000000000000000002732 203.0
SHD2_k127_3324216_4 MFS/sugar transport protein K03292 - - 0.000000000000000000000000000000000000000000000006497 189.0
SHD2_k127_3324216_5 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000001745 169.0
SHD2_k127_3324216_6 -acetyltransferase - - - 0.00007896 53.0
SHD2_k127_3328653_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000001286 239.0
SHD2_k127_3328653_2 PFAM NB-ARC domain K16247 - - 0.0000000000000008514 91.0
SHD2_k127_3331298_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008597 265.0
SHD2_k127_3331298_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006824 257.0
SHD2_k127_3331298_2 transcriptional regulator - - - 0.0000000000000000000000000009825 119.0
SHD2_k127_3331298_3 Protein of unknown function (DUF2877) - - - 0.000000000000000000000002727 113.0
SHD2_k127_3334842_0 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 370.0
SHD2_k127_3334842_1 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000964 171.0
SHD2_k127_3334842_3 Domain of unknown function DUF11 - - - 0.0001577 49.0
SHD2_k127_3342194_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 5.254e-250 802.0
SHD2_k127_3342194_1 SMART AAA ATPase - - - 7.43e-217 680.0
SHD2_k127_3342194_10 Tfp pilus assembly protein FimV - - - 0.0002629 52.0
SHD2_k127_3342194_2 Serine threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 469.0
SHD2_k127_3342194_3 AAA-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 445.0
SHD2_k127_3342194_4 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 325.0
SHD2_k127_3342194_5 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001711 266.0
SHD2_k127_3342194_6 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000764 259.0
SHD2_k127_3342194_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000006937 173.0
SHD2_k127_3342194_8 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000001647 139.0
SHD2_k127_3342194_9 Cytochrome c - - - 0.000001304 58.0
SHD2_k127_3357052_0 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 436.0
SHD2_k127_3357052_1 Family 4 glycosyl hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 375.0
SHD2_k127_3357052_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 361.0
SHD2_k127_3357052_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000003671 267.0
SHD2_k127_3357052_4 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000183 178.0
SHD2_k127_3367355_0 SMART alpha amylase, catalytic sub domain K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 2.431e-223 705.0
SHD2_k127_3367355_1 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 402.0
SHD2_k127_3367355_2 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 327.0
SHD2_k127_3367355_3 Acyltransferase family - - - 0.000000000000000000000000000000000005654 149.0
SHD2_k127_3367355_4 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000001215 138.0
SHD2_k127_3367355_5 Pkd domain containing protein - - - 0.0000000000002875 71.0
SHD2_k127_3367355_6 Cytochrome b5-like Heme Steroid binding domain - - - 0.0000000009616 64.0
SHD2_k127_3367355_7 monooxygenase activity K06966 - 3.2.2.10 0.0002488 47.0
SHD2_k127_3389986_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 464.0
SHD2_k127_3389986_1 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 416.0
SHD2_k127_3389986_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 406.0
SHD2_k127_3389986_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000005513 134.0
SHD2_k127_3421055_0 Helicase conserved C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 426.0
SHD2_k127_3421055_1 Short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 349.0
SHD2_k127_3421055_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 304.0
SHD2_k127_3421254_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 502.0
SHD2_k127_3421254_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 364.0
SHD2_k127_3421254_10 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000002486 81.0
SHD2_k127_3421254_11 Ribosomal protein L36 K02919 - - 0.0000000000003433 69.0
SHD2_k127_3421254_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001295 277.0
SHD2_k127_3421254_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005239 267.0
SHD2_k127_3421254_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000009788 239.0
SHD2_k127_3421254_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000284 224.0
SHD2_k127_3421254_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001768 210.0
SHD2_k127_3421254_7 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000919 199.0
SHD2_k127_3421254_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001103 173.0
SHD2_k127_3421254_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000001506 155.0
SHD2_k127_3425768_0 Protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 1.2e-240 788.0
SHD2_k127_3425768_1 Catalyzes the release of L-lysine from LysW -gamma-L- lysine K05831 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 371.0
SHD2_k127_3425768_2 Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine K05830 - - 0.000000000000000000000000000000000000000000003744 168.0
SHD2_k127_3425768_3 PFAM Stage V sporulation protein S K06416 - - 0.00000000000000000000000000000157 124.0
SHD2_k127_3425768_4 response regulator K07689 - - 0.00000000000000000000000000006498 120.0
SHD2_k127_3425768_5 response regulator K07689 - - 0.000000000000000000000001933 107.0
SHD2_k127_3425768_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000001228 95.0
SHD2_k127_3425768_7 GIY-YIG catalytic domain K07461 - - 0.000000000000001053 79.0
SHD2_k127_3444117_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.444e-290 919.0
SHD2_k127_3444117_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000003161 119.0
SHD2_k127_3454525_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1318.0
SHD2_k127_3454525_1 Protein of unknown function (DUF418) K07148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 539.0
SHD2_k127_3454525_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 327.0
SHD2_k127_3454525_3 - - - - 0.00000000000000000000134 96.0
SHD2_k127_3454525_4 PFAM Bacterial regulatory protein, arsR family K21903 - - 0.00000000000000000002456 95.0
SHD2_k127_3454525_5 Transcriptional activator domain - - - 0.00003292 49.0
SHD2_k127_3467442_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 598.0
SHD2_k127_3467442_2 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000003293 164.0
SHD2_k127_3467442_3 LysM domain K07273,K22278 - 3.5.1.104 0.0000000000000000000003597 106.0
SHD2_k127_3474719_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 4.097e-223 700.0
SHD2_k127_3474719_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K10545,K10548 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015148,GO:0015749,GO:0015750,GO:0015753,GO:0017076,GO:0019321,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042732,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 9.998e-199 631.0
SHD2_k127_3474719_2 COG1070 Sugar (pentulose and hexulose) kinases K00854,K00862 - 2.7.1.17,2.7.1.215 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 423.0
SHD2_k127_3474719_3 PFAM Branched-chain amino acid transport system permease component K10544,K10547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 370.0
SHD2_k127_3474719_4 Domain of unknown function (DUF4380) - - - 0.000000000000000000000000000000000000000000000000000000000000000776 229.0
SHD2_k127_3474719_5 Periplasmic binding protein domain K10543,K10546 - - 0.00000000000861 66.0
SHD2_k127_3484363_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 610.0
SHD2_k127_3484363_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000002712 213.0
SHD2_k127_3484363_2 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000003434 189.0
SHD2_k127_3487063_0 Multicopper oxidase K08100 - 1.3.3.5 0.0 1007.0
SHD2_k127_3487063_1 (ABC) transporter K06147 - - 5.117e-211 671.0
SHD2_k127_3487063_2 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 522.0
SHD2_k127_3487063_3 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 344.0
SHD2_k127_3487063_4 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000007679 205.0
SHD2_k127_3487063_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000002012 192.0
SHD2_k127_3487063_6 transcriptional - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000001561 61.0
SHD2_k127_3511072_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 2.414e-298 925.0
SHD2_k127_3511072_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 357.0
SHD2_k127_3511072_2 PFAM MerR family regulatory protein - - - 0.00000000000000000000000000000000000000000000000006532 188.0
SHD2_k127_3511072_3 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000845 161.0
SHD2_k127_3511072_4 - - - - 0.0000000000003275 76.0
SHD2_k127_3514939_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 359.0
SHD2_k127_3514939_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 334.0
SHD2_k127_3514939_10 Transcriptional regulator K13653 - - 0.0000000000000002449 86.0
SHD2_k127_3514939_11 ubiquitin binding K17987 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005829,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016043,GO:0016236,GO:0022607,GO:0031410,GO:0031982,GO:0032182,GO:0034622,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0051258,GO:0051259,GO:0061919,GO:0065003,GO:0071840,GO:0097708 - 0.0000000000009065 82.0
SHD2_k127_3514939_2 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 296.0
SHD2_k127_3514939_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000003673 269.0
SHD2_k127_3514939_4 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003162 254.0
SHD2_k127_3514939_5 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000002718 261.0
SHD2_k127_3514939_6 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000000000008155 183.0
SHD2_k127_3514939_7 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.00000000000000000000000000000000000000000000000001003 192.0
SHD2_k127_3514939_8 sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000231 184.0
SHD2_k127_3514939_9 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000004201 130.0
SHD2_k127_3519935_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 496.0
SHD2_k127_3519935_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 364.0
SHD2_k127_3519935_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001971 231.0
SHD2_k127_3519935_3 pseudouridine 5'-phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000004839 200.0
SHD2_k127_3519935_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000002552 189.0
SHD2_k127_3519935_5 alpha beta - - - 0.0000000000000000000000000000000000000000000000002685 189.0
SHD2_k127_3519935_6 - - - - 0.000000000000000000000000000000000000000000000000908 180.0
SHD2_k127_3519935_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000001864 125.0
SHD2_k127_3519935_8 EamA-like transporter family - - - 0.000000000000009754 76.0
SHD2_k127_3530968_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 328.0
SHD2_k127_3530968_1 Hydrolase Family 16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 308.0
SHD2_k127_3530968_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001012 281.0
SHD2_k127_3530968_3 ATPase AAA-2 domain protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001438 276.0
SHD2_k127_3530968_4 ATPase AAA-2 domain protein K03696 - - 0.000000000000000000000000000000000000000000004368 163.0
SHD2_k127_3530968_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000002838 104.0
SHD2_k127_35318_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1272.0
SHD2_k127_35318_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 428.0
SHD2_k127_35318_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 380.0
SHD2_k127_35318_3 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000004439 56.0
SHD2_k127_3544841_0 PFAM glycoside hydrolase, family 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 561.0
SHD2_k127_3544841_1 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 413.0
SHD2_k127_3544841_10 Thioredoxin - - - 0.0000000000000000000000000000000000001081 152.0
SHD2_k127_3544841_11 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000002075 100.0
SHD2_k127_3544841_12 - - - - 0.00000000000005213 74.0
SHD2_k127_3544841_13 antisigma factor binding K04749 - - 0.000006428 56.0
SHD2_k127_3544841_14 Involved in the tonB-independent uptake of proteins - - - 0.00001031 57.0
SHD2_k127_3544841_3 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 348.0
SHD2_k127_3544841_4 PFAM deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 298.0
SHD2_k127_3544841_5 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 303.0
SHD2_k127_3544841_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002495 291.0
SHD2_k127_3544841_7 Transcriptional regulatory protein, C terminal K07668,K07775 - - 0.00000000000000000000000000000000000000000000000000000000000000000333 233.0
SHD2_k127_3544841_8 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000001429 194.0
SHD2_k127_3544841_9 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000003052 176.0
SHD2_k127_3563677_0 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000001726 158.0
SHD2_k127_3563677_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000004182 165.0
SHD2_k127_3563677_2 - K01992 - - 0.00000000000000000000000000000404 128.0
SHD2_k127_3563677_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000306 124.0
SHD2_k127_3563677_4 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000001622 113.0
SHD2_k127_3563677_5 AntiSigma factor - - - 0.000000000000005312 85.0
SHD2_k127_3563677_6 PFAM Cyclic nucleotide-binding domain - - - 0.00000000002269 66.0
SHD2_k127_3572215_0 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 452.0
SHD2_k127_3572215_1 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 367.0
SHD2_k127_3572215_2 import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000146 272.0
SHD2_k127_3572215_3 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000001422 240.0
SHD2_k127_3572215_4 Cupin domain - - - 0.00000000000000000000000000000000005089 137.0
SHD2_k127_3581017_0 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 303.0
SHD2_k127_3581017_1 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002299 263.0
SHD2_k127_3581017_10 Pfam:DUF385 - - - 0.00000000001283 72.0
SHD2_k127_3581017_11 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.000002733 55.0
SHD2_k127_3581017_12 Belongs to the anti-sigma-factor antagonist family - - - 0.0001663 49.0
SHD2_k127_3581017_2 FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000003009 226.0
SHD2_k127_3581017_3 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000002132 203.0
SHD2_k127_3581017_4 Putative esterase K07017 - - 0.0000000000000000000000000000000000000000000000000001713 197.0
SHD2_k127_3581017_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000002074 175.0
SHD2_k127_3581017_6 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000008742 142.0
SHD2_k127_3581017_8 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000005846 121.0
SHD2_k127_3581176_0 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 479.0
SHD2_k127_3581176_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 319.0
SHD2_k127_3581176_2 enzyme binding K00567,K07443 - 2.1.1.63 0.000000000000005639 81.0
SHD2_k127_3581176_3 - - - - 0.0000000000004289 72.0
SHD2_k127_3581176_5 WD40-like Beta Propeller Repeat K03641 - - 0.000127 53.0
SHD2_k127_3598314_0 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 578.0
SHD2_k127_3725010_0 Elongator protein 3, MiaB family, Radical SAM - - - 1.292e-261 820.0
SHD2_k127_3725010_1 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 494.0
SHD2_k127_3725010_10 Ferritin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000001671 233.0
SHD2_k127_3725010_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000007928 223.0
SHD2_k127_3725010_12 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002136 221.0
SHD2_k127_3725010_13 - K14340 - - 0.00000000000000000000000000000000000000000000000000000000001101 226.0
SHD2_k127_3725010_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000001892 184.0
SHD2_k127_3725010_15 radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000001735 176.0
SHD2_k127_3725010_16 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000000000397 173.0
SHD2_k127_3725010_17 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000002054 160.0
SHD2_k127_3725010_18 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000002412 128.0
SHD2_k127_3725010_19 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000019 108.0
SHD2_k127_3725010_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 382.0
SHD2_k127_3725010_20 Protein of unknown function (DUF1706) - - - 0.0000000000001878 77.0
SHD2_k127_3725010_21 DinB superfamily - - - 0.000000002268 61.0
SHD2_k127_3725010_22 Ami_3 K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.00000007581 64.0
SHD2_k127_3725010_23 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain K05989 - 3.2.1.40 0.00002039 56.0
SHD2_k127_3725010_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 359.0
SHD2_k127_3725010_4 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001797 276.0
SHD2_k127_3725010_5 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001742 263.0
SHD2_k127_3725010_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007485 269.0
SHD2_k127_3725010_7 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003939 254.0
SHD2_k127_3725010_8 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000009923 247.0
SHD2_k127_3725010_9 PFAM response regulator receiver K02483,K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000004007 236.0
SHD2_k127_3725686_0 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 422.0
SHD2_k127_3725686_1 FGGY family of carbohydrate kinases, N-terminal domain K00854,K00862,K00880 - 2.7.1.17,2.7.1.215,2.7.1.53 0.000000000000000000000000000000000000000000000000000000000005379 212.0
SHD2_k127_3757806_0 Pfam:KaiC K08482 - - 1.979e-198 629.0
SHD2_k127_3757806_1 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000002799 188.0
SHD2_k127_3757806_2 KaiB K08481 - - 0.0000000000000000000000000000000000000004752 157.0
SHD2_k127_3757806_3 response regulator K07689 - - 0.00000000000000000000000002018 115.0
SHD2_k127_3762703_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 574.0
SHD2_k127_3762703_1 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000001852 179.0
SHD2_k127_3762703_2 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000000006394 106.0
SHD2_k127_3762703_3 Belongs to the glycosyl hydrolase 18 family K01183 - 3.2.1.14 0.0000001152 64.0
SHD2_k127_3833931_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 448.0
SHD2_k127_3833931_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 435.0
SHD2_k127_3833931_2 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
SHD2_k127_3833931_3 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000001177 128.0
SHD2_k127_3833931_4 Ig-like domain from next to BRCA1 gene - GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919 - 0.000000000000001106 86.0
SHD2_k127_3833931_5 - - - - 0.00000000000004053 77.0
SHD2_k127_3833931_6 ABC-2 type transporter K01992 - - 0.0000000000005019 72.0
SHD2_k127_3855590_0 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000001809 230.0
SHD2_k127_3855590_1 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.0000000000000000000000000000000000000000000009704 169.0
SHD2_k127_3855590_2 TIR domain - - - 0.0000000000000000000000000000000000000001281 161.0
SHD2_k127_3855590_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000005732 51.0
SHD2_k127_3877713_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 8.112e-253 798.0
SHD2_k127_3877713_1 Uncharacterised ACR (DUF711) K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 381.0
SHD2_k127_3877713_10 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000004431 70.0
SHD2_k127_3877713_2 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 381.0
SHD2_k127_3877713_3 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 320.0
SHD2_k127_3877713_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004924 251.0
SHD2_k127_3877713_5 Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation - GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231 - 0.000000000000000000000000000000000000000000000000000000678 198.0
SHD2_k127_3877713_6 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000001927 193.0
SHD2_k127_3877713_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000002319 179.0
SHD2_k127_3877713_8 PFAM CHAD domain containing protein K08296 - - 0.000000000000000000000000000000000000000004141 166.0
SHD2_k127_3877713_9 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000009416 108.0
SHD2_k127_3887419_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 327.0
SHD2_k127_3887419_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000006654 148.0
SHD2_k127_3887419_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000002527 78.0
SHD2_k127_389539_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 321.0
SHD2_k127_389539_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000001572 173.0
SHD2_k127_3919650_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 4.297e-199 635.0
SHD2_k127_3919650_1 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 334.0
SHD2_k127_3919650_2 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 303.0
SHD2_k127_3919650_3 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000353 88.0
SHD2_k127_3920397_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 302.0
SHD2_k127_3920397_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008516 267.0
SHD2_k127_3920397_10 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000001258 125.0
SHD2_k127_3920397_2 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001512 267.0
SHD2_k127_3920397_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000009532 267.0
SHD2_k127_3920397_5 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000007161 171.0
SHD2_k127_3920397_6 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000000001005 171.0
SHD2_k127_3920397_7 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000907 159.0
SHD2_k127_3920397_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000005735 146.0
SHD2_k127_3920397_9 NUDIX domain - - - 0.00000000000000000000000000004595 121.0
SHD2_k127_3972481_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 362.0
SHD2_k127_3972481_1 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 363.0
SHD2_k127_3972481_2 conserved protein (DUF2174) - - - 0.000000000000000000000000000000000000000000000000000000000000144 218.0
SHD2_k127_3972481_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000002669 160.0
SHD2_k127_3972481_4 Protein of unknown function (DUF1706) - - - 0.0000000000000000000000000000005432 127.0
SHD2_k127_3972481_6 - - - - 0.00000000000000000000000009635 118.0
SHD2_k127_3972481_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000002729 83.0
SHD2_k127_3972481_8 PspC domain K03973 - - 0.0000000000004363 73.0
SHD2_k127_3985457_0 protein flavinylation K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000304 281.0
SHD2_k127_3985457_1 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000003775 177.0
SHD2_k127_3985457_2 FMN_bind - - - 0.000000000000000000000001344 110.0
SHD2_k127_400769_0 Putative glucoamylase K13688 - - 0.0 2178.0
SHD2_k127_400769_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000006561 123.0
SHD2_k127_400769_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000113 115.0
SHD2_k127_400769_3 UPF0391 membrane protein - - - 0.000000000005528 68.0
SHD2_k127_400769_4 sh3 domain protein K01448,K04771 - 3.4.21.107,3.5.1.28 0.0000008022 59.0
SHD2_k127_400769_5 PRC-barrel domain - - - 0.0005959 50.0
SHD2_k127_4034854_0 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 572.0
SHD2_k127_4034854_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K18005 - 1.12.1.2,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 528.0
SHD2_k127_4034854_2 Belongs to the glycosyl hydrolase 12 (cellulase H) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 360.0
SHD2_k127_4034854_3 formate dehydrogenase (NAD+) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 341.0
SHD2_k127_4034854_4 Class II Aldolase and Adducin N-terminal domain K01629 - 4.1.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 302.0
SHD2_k127_4034854_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000007529 159.0
SHD2_k127_4034854_6 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000005078 129.0
SHD2_k127_4034854_7 Nodulation protein S (NodS) - - - 0.00000000003495 74.0
SHD2_k127_4034854_8 integron gene cassette protein - - - 0.0000004411 55.0
SHD2_k127_404088_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1082.0
SHD2_k127_404088_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 530.0
SHD2_k127_404088_11 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000004706 51.0
SHD2_k127_404088_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 323.0
SHD2_k127_404088_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008694 250.0
SHD2_k127_404088_4 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000003794 218.0
SHD2_k127_404088_5 - - - - 0.000000000000000000000000000000000000000000002093 168.0
SHD2_k127_404088_6 acetyltransferase K03826 - - 0.0000000000000000000000000000002934 127.0
SHD2_k127_404088_7 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000005169 117.0
SHD2_k127_404088_8 - - - - 0.00000000000000000000000000961 114.0
SHD2_k127_404088_9 response regulator K03413,K07719 - - 0.000000000000000000000000116 110.0
SHD2_k127_4050334_0 SMART alpha amylase, catalytic sub domain K01176 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 489.0
SHD2_k127_4050334_1 PFAM binding-protein-dependent transport systems inner membrane component K15771 - - 0.00000000000000000000000005828 125.0
SHD2_k127_4055042_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 501.0
SHD2_k127_4055042_3 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.000000000000000000001565 98.0
SHD2_k127_406135_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 377.0
SHD2_k127_406135_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 364.0
SHD2_k127_406135_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000001148 117.0
SHD2_k127_4068523_0 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 303.0
SHD2_k127_4068523_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000001239 241.0
SHD2_k127_4068523_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000641 147.0
SHD2_k127_4103065_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 383.0
SHD2_k127_4103065_1 Ribose ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006479 282.0
SHD2_k127_4103065_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000007913 258.0
SHD2_k127_4103065_3 BMC - - - 0.0000000000000000000000000000000000000000000000000000000000004745 216.0
SHD2_k127_4103065_4 Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization K03078 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009056,GO:0009109,GO:0009111,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0019852,GO:0019854,GO:0033982,GO:0042365,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0051186,GO:0051187,GO:0071704,GO:1901575 4.1.1.85 0.0000000000000000000000000000000000000000000000000001708 199.0
SHD2_k127_4103065_5 PFAM microcompartments protein K04027 - - 0.00000000000000000000000000004037 120.0
SHD2_k127_4103065_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000001235 124.0
SHD2_k127_4103065_7 BMC domain - - - 0.0000000000000000000000000004458 116.0
SHD2_k127_4103065_8 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.00000000000000000000001525 102.0
SHD2_k127_4191988_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733,K22010 - 4.2.3.1 7.426e-219 691.0
SHD2_k127_4191988_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 451.0
SHD2_k127_4191988_2 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005837 259.0
SHD2_k127_4191988_3 PFAM response regulator receiver K11443 - - 0.000000000000000000000000000000000000001261 150.0
SHD2_k127_42264_0 PFAM regulatory protein, MerR K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 347.0
SHD2_k127_42264_1 PFAM Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 331.0
SHD2_k127_42264_2 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002045 273.0
SHD2_k127_42264_3 PFAM GDSL-like Lipase Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000004451 220.0
SHD2_k127_42264_4 Putative zincin peptidase - - - 0.00009998 48.0
SHD2_k127_4234313_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 423.0
SHD2_k127_4234313_1 oxidoreductase activity K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000001576 227.0
SHD2_k127_4234313_10 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000001494 56.0
SHD2_k127_4234313_11 SdpI/YhfL protein family - - - 0.0000002574 57.0
SHD2_k127_4234313_12 - - - - 0.000007552 55.0
SHD2_k127_4234313_13 sequence-specific DNA binding - - - 0.00003666 56.0
SHD2_k127_4234313_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins K02674,K07004 - - 0.000000000000000000000000000000000003585 155.0
SHD2_k127_4234313_3 - - - - 0.0000000000000000000000000001378 117.0
SHD2_k127_4234313_4 cellulose binding - - - 0.0000000000000000002794 101.0
SHD2_k127_4234313_5 Domain in cystathionine beta-synthase and other proteins. K07448 - - 0.00000000000001036 87.0
SHD2_k127_4234313_6 - - - - 0.0000000000005657 81.0
SHD2_k127_4234313_7 photosynthesis - - - 0.0000000000257 74.0
SHD2_k127_4234313_8 peptidyl-tyrosine sulfation - - - 0.0000000001135 68.0
SHD2_k127_4234313_9 Sugar (and other) transporter - - - 0.00000002241 62.0
SHD2_k127_4241082_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 2.486e-235 740.0
SHD2_k127_4241082_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 548.0
SHD2_k127_4241082_2 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 466.0
SHD2_k127_4241082_3 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 299.0
SHD2_k127_4241082_4 TIGRFAM Competence protein ComEA, helix-hairpin-helix K17717 - 3.1.4.4 0.0000000000000000000000000000000000007308 142.0
SHD2_k127_4241082_5 META domain K03668 - - 0.00000000004471 70.0
SHD2_k127_4246607_0 domain, Protein K01219,K17624 - 3.2.1.81,3.2.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005216 283.0
SHD2_k127_4246607_1 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000001266 230.0
SHD2_k127_4246607_2 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000007495 182.0
SHD2_k127_4246607_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000001386 169.0
SHD2_k127_4246607_4 - - - - 0.00000000000000000000000000000008975 136.0
SHD2_k127_4255979_0 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 1.246e-238 750.0
SHD2_k127_4255979_1 PFAM alpha-2-macroglobulin domain protein K06894 - - 1.534e-196 662.0
SHD2_k127_4255979_2 N-terminal domain of oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 310.0
SHD2_k127_4255979_3 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000008634 184.0
SHD2_k127_4255979_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001438 153.0
SHD2_k127_4255979_5 PFAM regulatory protein TetR - - - 0.00000000000000000000000000006617 123.0
SHD2_k127_4273526_0 Transcriptional activator domain - - - 1.781e-243 782.0
SHD2_k127_4273526_1 Alcohol dehydrogenase, class IV K00217 - 1.3.1.32 0.000000000000000000000000000000000000000000000000000000000000004673 230.0
SHD2_k127_4273526_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000001396 168.0
SHD2_k127_4310346_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 572.0
SHD2_k127_4310346_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000001094 111.0
SHD2_k127_4310346_2 Transcriptional regulatory protein, C terminal K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000001047 69.0
SHD2_k127_431093_0 photoreceptor activity K02476 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 383.0
SHD2_k127_431093_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005132 263.0
SHD2_k127_431093_2 response regulator, receiver K02485 - - 0.00000000000000000000000000000000000000000000001165 175.0
SHD2_k127_433240_0 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 312.0
SHD2_k127_433240_1 Putative cell wall binding repeat - - - 0.00002511 55.0
SHD2_k127_4363101_0 Porphobilinogen deaminase, dipyromethane cofactor binding domain K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000001857 264.0
SHD2_k127_4363101_1 precorrin-2 dehydrogenase activity K02302,K02303,K02304,K03795,K04719,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79,1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.3,4.99.1.4 0.0000000000000000000000000000000000000003846 153.0
SHD2_k127_4363101_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000002313 137.0
SHD2_k127_4398807_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 582.0
SHD2_k127_4398807_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 469.0
SHD2_k127_4398807_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 472.0
SHD2_k127_4398807_3 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 340.0
SHD2_k127_4405852_0 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 2.119e-303 942.0
SHD2_k127_4405852_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.427e-284 887.0
SHD2_k127_4405852_10 Psort location CytoplasmicMembrane, score - - - 0.000000000000000001109 100.0
SHD2_k127_4405852_11 Sporulation and spore germination - - - 0.0000000000000001414 94.0
SHD2_k127_4405852_12 von Willebrand factor (vWF) type A domain - - - 0.00000000000232 67.0
SHD2_k127_4405852_2 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 492.0
SHD2_k127_4405852_3 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 368.0
SHD2_k127_4405852_5 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000003095 247.0
SHD2_k127_4405852_6 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002781 214.0
SHD2_k127_4405852_7 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000003628 186.0
SHD2_k127_4405852_8 - - - - 0.0000000000000000000000000000000000000000000000005476 183.0
SHD2_k127_4405852_9 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.0000000000000000000000000002946 122.0
SHD2_k127_4407626_0 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 451.0
SHD2_k127_4407626_1 belongs to the aldehyde dehydrogenase family K00132 - 1.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 317.0
SHD2_k127_4407626_2 PFAM BMC domain K04026 - - 0.000000000000000000000000000000000000000000000000000000000000000000001581 242.0
SHD2_k127_441937_0 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 320.0
SHD2_k127_441937_1 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 322.0
SHD2_k127_441937_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000162 257.0
SHD2_k127_441937_4 response regulator K07669 - - 0.0000000000000000000000000000000000000000000000000000004919 201.0
SHD2_k127_441937_5 histidine kinase dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000002356 165.0
SHD2_k127_441937_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000007356 145.0
SHD2_k127_441937_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000008491 85.0
SHD2_k127_441937_8 Anti-sigma-K factor rskA - - - 0.000002641 51.0
SHD2_k127_4422847_0 PFAM ABC transporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 614.0
SHD2_k127_4422847_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004667 288.0
SHD2_k127_4422847_2 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002258 274.0
SHD2_k127_4422847_3 FtsZ-dependent cytokinesis K03975,K18292,K19302 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944 3.6.1.27,4.1.3.25 0.0000000000000000000107 103.0
SHD2_k127_4431114_0 histidine kinase A domain protein - - - 1.192e-196 623.0
SHD2_k127_4431114_1 FIST N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001054 283.0
SHD2_k127_4431114_2 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000001255 235.0
SHD2_k127_4431114_3 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000002876 134.0
SHD2_k127_4439785_0 Selenocysteine-specific translation elongation factor K03833 - - 7.856e-238 753.0
SHD2_k127_4439785_1 Proton-conducting membrane transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 303.0
SHD2_k127_4439785_2 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002527 288.0
SHD2_k127_4440785_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 2.491e-230 720.0
SHD2_k127_4440785_1 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 370.0
SHD2_k127_4440785_2 Stage II sporulation K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 359.0
SHD2_k127_4440785_3 PFAM deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 325.0
SHD2_k127_4440785_4 Cellulose biosynthesis protein BcsQ K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000004171 239.0
SHD2_k127_4440785_5 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000002543 235.0
SHD2_k127_4440785_6 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000003951 166.0
SHD2_k127_4440785_7 - - - - 0.0000000000000000000000000000000000005357 147.0
SHD2_k127_4440785_8 - - - - 0.000009522 52.0
SHD2_k127_4440785_9 O-acetylhomoserine K01740 - 2.5.1.49 0.00001483 47.0
SHD2_k127_4442621_0 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 397.0
SHD2_k127_4442621_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 319.0
SHD2_k127_4446319_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 460.0
SHD2_k127_4446319_1 3-carboxyethylcatechol 2,3-dioxygenase activity K04100 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000009619 230.0
SHD2_k127_4446319_2 - - - - 0.0000000000000000000000000000000000000000000008325 171.0
SHD2_k127_4446319_3 - - - - 0.0000000000000000000009181 101.0
SHD2_k127_4446319_4 Transglycosylase associated protein - - - 0.0000000000000000000168 93.0
SHD2_k127_4446319_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000002074 95.0
SHD2_k127_4446319_6 transposition K07497 - - 0.00000000001397 69.0
SHD2_k127_4446319_7 transposition K07497 - - 0.0000000003574 62.0
SHD2_k127_4446319_8 CsbD-like - - - 0.0005303 44.0
SHD2_k127_4446815_0 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 322.0
SHD2_k127_4446815_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001374 251.0
SHD2_k127_4446815_2 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000009483 138.0
SHD2_k127_4446815_3 Protein of unknown function (DUF998) - - - 0.0000000000001503 79.0
SHD2_k127_4447757_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 390.0
SHD2_k127_4449350_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 471.0
SHD2_k127_4449350_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 430.0
SHD2_k127_4449350_2 cytidylyl-transferase K00983 - 2.7.7.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 301.0
SHD2_k127_4449350_3 alpha-galactosidase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003215 278.0
SHD2_k127_4449350_4 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000002892 236.0
SHD2_k127_4449350_5 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000001101 211.0
SHD2_k127_4449350_6 Sulfotransferase domain - - - 0.00000000000000000000000000000000254 140.0
SHD2_k127_446995_0 PFAM fumarate lyase K01679 - 4.2.1.2 1.908e-197 625.0
SHD2_k127_446995_1 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 378.0
SHD2_k127_446995_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000003854 119.0
SHD2_k127_446995_3 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0000000000000000008479 89.0
SHD2_k127_4483893_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1059.0
SHD2_k127_4483893_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 538.0
SHD2_k127_4483893_10 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000211 133.0
SHD2_k127_4483893_11 Beta-lactamase superfamily domain - - - 0.00000000004444 65.0
SHD2_k127_4483893_12 amine dehydrogenase activity - - - 0.000000001535 70.0
SHD2_k127_4483893_13 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.00000001766 57.0
SHD2_k127_4483893_2 FGGY family of carbohydrate kinases, N-terminal domain K00880 - 2.7.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 509.0
SHD2_k127_4483893_3 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 439.0
SHD2_k127_4483893_4 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 313.0
SHD2_k127_4483893_5 PFAM ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000005599 247.0
SHD2_k127_4483893_6 transcriptional regulator K13641 - - 0.000000000000000000000000000000000000000000000000000000000000000000008361 243.0
SHD2_k127_4483893_7 Belongs to the HAD-like hydrolase superfamily K01101 - 3.1.3.41 0.00000000000000000000000000000000000000000000000000000000000000000007439 239.0
SHD2_k127_4483893_8 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000001776 238.0
SHD2_k127_4483893_9 6-phospho 3-hexuloisomerase K08094 - 5.3.1.27 0.0000000000000000000000000000000000000001373 157.0
SHD2_k127_4489682_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 7.576e-259 807.0
SHD2_k127_4489682_1 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 1.732e-200 630.0
SHD2_k127_4489682_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 434.0
SHD2_k127_4489682_3 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000002059 123.0
SHD2_k127_4489682_4 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000001001 121.0
SHD2_k127_4496642_0 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 395.0
SHD2_k127_4496642_1 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 368.0
SHD2_k127_4496642_2 Putative zincin peptidase - - - 0.00000000000000000000000000000000000000001209 156.0
SHD2_k127_4496655_0 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 289.0
SHD2_k127_4496655_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000001236 246.0
SHD2_k127_4496655_2 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000000000000000000001848 183.0
SHD2_k127_4496655_3 Ribosomal L27 protein K02899 - - 0.00000000000000002656 82.0
SHD2_k127_4496655_5 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000003085 63.0
SHD2_k127_4511339_0 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 464.0
SHD2_k127_4511339_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000009943 113.0
SHD2_k127_4530016_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 1.031e-216 691.0
SHD2_k127_4530016_1 transferase activity, transferring acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 343.0
SHD2_k127_4530016_10 Transcriptional regulatory protein, C terminal K07667 - - 0.0000002551 59.0
SHD2_k127_4530016_2 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000009557 234.0
SHD2_k127_4530016_3 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000002314 207.0
SHD2_k127_4530016_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025,K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000006872 164.0
SHD2_k127_4530016_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000217 151.0
SHD2_k127_4530016_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000171 139.0
SHD2_k127_4530016_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000001829 125.0
SHD2_k127_4530016_8 ABC transporter substrate-binding protein PnrA-like K02058,K05519,K07335 - - 0.0000000000000000002512 100.0
SHD2_k127_4530016_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000001895 88.0
SHD2_k127_453810_0 Histidine kinase K07646 - 2.7.13.3 1.816e-195 627.0
SHD2_k127_453810_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004662 250.0
SHD2_k127_453810_2 Amino acid permease - - - 0.000000004828 69.0
SHD2_k127_4540438_0 - - - - 0.0000000000000000000000000000000002584 134.0
SHD2_k127_4540438_1 NB-ARC domain - - - 0.0000000000000000004738 100.0
SHD2_k127_4554042_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 414.0
SHD2_k127_4554042_1 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 338.0
SHD2_k127_4554042_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000001116 191.0
SHD2_k127_4554042_3 GGDEF domain K01768,K20977 - 4.6.1.1 0.000000000000000000000000000000000000000004817 168.0
SHD2_k127_4567111_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 309.0
SHD2_k127_4567111_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000001659 236.0
SHD2_k127_4567111_2 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000003258 230.0
SHD2_k127_4567111_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000002468 228.0
SHD2_k127_4567111_4 mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000000000000003738 192.0
SHD2_k127_4567111_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000001957 84.0
SHD2_k127_4567111_6 - - - - 0.00000000000005642 75.0
SHD2_k127_4599427_0 amino acid K03294 - - 5.131e-225 709.0
SHD2_k127_4599427_1 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 397.0
SHD2_k127_4599427_2 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 353.0
SHD2_k127_4599427_3 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 306.0
SHD2_k127_4599427_4 - - - - 0.00000000000000000000000000000000000000000000000003521 188.0
SHD2_k127_4599427_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000001445 158.0
SHD2_k127_4599427_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000003845 130.0
SHD2_k127_4599427_7 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.0000000000000000000000008212 109.0
SHD2_k127_4599427_8 Protein of unknown function DUF47 K07220 - - 0.0000000000003316 71.0
SHD2_k127_4601990_0 SERine Proteinase INhibitors K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 380.0
SHD2_k127_4601990_1 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000002051 141.0
SHD2_k127_4620531_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 455.0
SHD2_k127_4620531_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 421.0
SHD2_k127_4620531_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 422.0
SHD2_k127_4620531_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 377.0
SHD2_k127_4620531_4 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 312.0
SHD2_k127_4620531_5 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000005663 268.0
SHD2_k127_4620531_6 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000003197 246.0
SHD2_k127_4620531_7 PFAM Transglycosylase associated protein - - - 0.000000000000000000000000105 109.0
SHD2_k127_4620531_8 Type II restriction enzyme, methylase subunits - - - 0.000000000000000000259 92.0
SHD2_k127_4623347_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0 1137.0
SHD2_k127_4623347_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 404.0
SHD2_k127_4623347_2 PFAM Ribose galactose isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000005394 205.0
SHD2_k127_4623347_3 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000002833 200.0
SHD2_k127_4623347_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000002703 171.0
SHD2_k127_4623347_5 Cupin domain protein - - - 0.000008726 53.0
SHD2_k127_4624058_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 560.0
SHD2_k127_4624058_1 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 329.0
SHD2_k127_4624058_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005444 278.0
SHD2_k127_4624058_3 lipid binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001739 257.0
SHD2_k127_4624058_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000001369 209.0
SHD2_k127_4624058_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000003494 185.0
SHD2_k127_4624058_6 - - - - 0.0000000000000000000012 109.0
SHD2_k127_4624058_7 - - - - 0.00000000000000000001275 107.0
SHD2_k127_4624058_8 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000001694 61.0
SHD2_k127_4632333_0 Bacterial extracellular solute-binding protein K10117 - - 3.356e-219 687.0
SHD2_k127_4632333_1 Glycosyl hydrolases family 43 K01198,K01209 - 3.2.1.37,3.2.1.55 1.491e-216 688.0
SHD2_k127_4632333_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 492.0
SHD2_k127_4632333_3 Binding-protein-dependent transport system inner membrane component K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 373.0
SHD2_k127_4632333_4 Binding-protein-dependent transport system inner membrane component K10119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 370.0
SHD2_k127_4632333_5 Belongs to the glycosyl hydrolase 8 (cellulase D) family K15531 - 3.2.1.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003344 268.0
SHD2_k127_4634867_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 546.0
SHD2_k127_4634867_1 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 363.0
SHD2_k127_4634867_2 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001064 256.0
SHD2_k127_4634867_3 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.000000000000000000000000000000000000000000000003497 186.0
SHD2_k127_4634867_4 integral membrane protein - - - 0.00000000000000000232 88.0
SHD2_k127_4634965_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 368.0
SHD2_k127_4634965_1 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001279 290.0
SHD2_k127_4634965_2 methenyltetrahydrofolate cyclohydrolase activity - - - 0.00000000000000000000000000000000000001645 145.0
SHD2_k127_4644575_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 311.0
SHD2_k127_4644575_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 297.0
SHD2_k127_4644575_2 MacB-like periplasmic core domain - - - 0.00000000000000000000002532 103.0
SHD2_k127_4644575_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00008969 51.0
SHD2_k127_4648227_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 466.0
SHD2_k127_4648227_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 379.0
SHD2_k127_4648227_2 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 306.0
SHD2_k127_4648227_3 - - - - 0.0000000000000000000000000009088 114.0
SHD2_k127_4648227_4 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000009558 96.0
SHD2_k127_4648227_5 - - - - 0.00003134 48.0
SHD2_k127_4679119_0 PFAM AAA ATPase central domain protein K07478 - - 1.578e-209 661.0
SHD2_k127_4679119_1 - - - - 0.00000000000000000000131 102.0
SHD2_k127_4686065_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 299.0
SHD2_k127_4686065_1 geranylgeranyl reductase activity - - - 0.000000000000000000000000000000000003738 148.0
SHD2_k127_470538_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) K00164 GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 449.0
SHD2_k127_47179_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 616.0
SHD2_k127_47179_1 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 583.0
SHD2_k127_47179_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000007857 140.0
SHD2_k127_47179_2 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 491.0
SHD2_k127_47179_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 424.0
SHD2_k127_47179_4 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 406.0
SHD2_k127_47179_5 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 335.0
SHD2_k127_47179_6 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005654 284.0
SHD2_k127_47179_7 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000001159 241.0
SHD2_k127_47179_8 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000008181 188.0
SHD2_k127_47179_9 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000003034 134.0
SHD2_k127_4724642_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.326e-220 694.0
SHD2_k127_4724642_1 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 615.0
SHD2_k127_4724642_10 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000001273 167.0
SHD2_k127_4724642_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.00000000000000000000000000000001123 131.0
SHD2_k127_4724642_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000004391 117.0
SHD2_k127_4724642_13 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0006339 46.0
SHD2_k127_4724642_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 575.0
SHD2_k127_4724642_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 451.0
SHD2_k127_4724642_4 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 444.0
SHD2_k127_4724642_5 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 320.0
SHD2_k127_4724642_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 301.0
SHD2_k127_4724642_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 255.0
SHD2_k127_4724642_8 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009512 252.0
SHD2_k127_4724642_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000012 213.0
SHD2_k127_4737318_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein K01354 - 3.4.21.83 5.245e-208 667.0
SHD2_k127_4737318_1 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 371.0
SHD2_k127_474281_0 Lysophospholipase K01048 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000007952 234.0
SHD2_k127_474281_1 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000005729 171.0
SHD2_k127_474281_2 Thioredoxin - - - 0.000000000000000000000000000000000006509 147.0
SHD2_k127_474281_3 peptidyl-tyrosine sulfation - - - 0.0000000000000001278 83.0
SHD2_k127_474281_4 4-vinyl reductase, 4VR K07013,K17763 - - 0.00000000000007016 81.0
SHD2_k127_474281_5 DSBA-like thioredoxin domain - - - 0.0000000001107 68.0
SHD2_k127_474281_6 V4R K07013 - - 0.0007289 49.0
SHD2_k127_4758647_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 298.0
SHD2_k127_4758647_1 PFAM major facilitator superfamily MFS_1 K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000002538 252.0
SHD2_k127_4758647_2 membrane K08987 - - 0.00000000000000000000000000000000000001106 151.0
SHD2_k127_4758647_3 Methyltransferase - - - 0.000000000000000000000000000007599 126.0
SHD2_k127_4758647_4 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000073 109.0
SHD2_k127_4758647_5 Protein of unknown function (DUF998) - - - 0.000124 51.0
SHD2_k127_4759703_0 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 331.0
SHD2_k127_4759703_1 COG3639 ABC-type phosphate phosphonate transport system, permease component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000007653 252.0
SHD2_k127_4759703_2 organic phosphonate transport K02044 - - 0.000000000000000000000000000000000000000000000000001126 197.0
SHD2_k127_4759703_3 PFAM Stage V sporulation protein S K06416 - - 0.00000000000000000000000000000000006624 136.0
SHD2_k127_4772301_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 1.599e-240 749.0
SHD2_k127_4772301_1 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000001572 200.0
SHD2_k127_4772301_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000001389 175.0
SHD2_k127_4772301_3 lipid binding - - - 0.0000000000000000000003655 104.0
SHD2_k127_4772301_4 DegV family - - - 0.000000000000000000001319 98.0
SHD2_k127_4772301_5 -acetyltransferase K06975 - - 0.000000000000009071 79.0
SHD2_k127_4772942_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 9.016e-219 686.0
SHD2_k127_4772942_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.527e-216 683.0
SHD2_k127_4772942_10 - - - - 0.00000001025 68.0
SHD2_k127_4772942_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 310.0
SHD2_k127_4772942_3 PFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001259 262.0
SHD2_k127_4772942_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000001369 209.0
SHD2_k127_4772942_5 PFAM Pyruvate K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000005333 196.0
SHD2_k127_4772942_6 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000005326 164.0
SHD2_k127_4772942_7 Dual specificity phosphatase, catalytic domain - - - 0.000000000000000000000000000000000000003694 152.0
SHD2_k127_4772942_8 methyltransferase - - - 0.000000000000000000000000006465 115.0
SHD2_k127_4778278_0 ATPase activity K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000118 199.0
SHD2_k127_4778278_1 Cobalt transport protein K02008,K16785 - - 0.000000000000000000000000000000000000000000000000003066 190.0
SHD2_k127_4778278_2 phosphorelay sensor kinase activity K16923,K18967 - 2.7.7.65 0.00000000000000000000000000000000000000000000001074 181.0
SHD2_k127_4778278_3 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.000000000000000000000000000000000004276 141.0
SHD2_k127_4786164_0 - - - - 8.551e-235 747.0
SHD2_k127_4786164_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 377.0
SHD2_k127_4786164_2 succinate dehydrogenase K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000002524 173.0
SHD2_k127_4794156_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 588.0
SHD2_k127_4794156_1 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000001591 228.0
SHD2_k127_4794156_2 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000001099 154.0
SHD2_k127_4794156_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K20810 - 3.5.4.40 0.000000000000000000000000001803 115.0
SHD2_k127_4794156_4 - - - - 0.000001976 58.0
SHD2_k127_4801800_0 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 346.0
SHD2_k127_4801800_1 Peptidase family S51 - - - 0.00000000000000000000000000000000000000004115 160.0
SHD2_k127_4801800_2 Protein of unknown function (DUF456) K09793 - - 0.0000000000000004526 81.0
SHD2_k127_4801800_3 Bacterial extracellular solute-binding protein K02027 - - 0.000000009264 68.0
SHD2_k127_4801800_4 M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.000001576 51.0
SHD2_k127_4810702_0 'PFAM Alpha amylase, catalytic K00690 GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615 2.4.1.7 3.008e-218 685.0
SHD2_k127_4810702_1 Bacterial extracellular solute-binding protein K02027,K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 531.0
SHD2_k127_4810702_10 glyoxalase III activity - - - 0.0000000000000044 82.0
SHD2_k127_4810702_11 to M. xanthus CarD K07736 - - 0.000000000157 69.0
SHD2_k127_4810702_2 COG1668 ABC-type Na efflux pump, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 426.0
SHD2_k127_4810702_3 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 387.0
SHD2_k127_4810702_4 Binding-protein-dependent transport system inner membrane component K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 383.0
SHD2_k127_4810702_5 Binding-protein-dependent transport system inner membrane component K10119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 370.0
SHD2_k127_4810702_6 PFAM Bacterial regulatory proteins, lacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 332.0
SHD2_k127_4810702_7 COG COG1073 Hydrolases of the alpha beta superfamily - - - 0.00000000000000000000000000000005046 128.0
SHD2_k127_4810702_8 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000629 130.0
SHD2_k127_4810702_9 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000003836 108.0
SHD2_k127_4840965_0 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 513.0
SHD2_k127_4840965_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 451.0
SHD2_k127_4840965_10 SnoaL-like polyketide cyclase K15945 - - 0.000000000000000000000000000000000000007054 151.0
SHD2_k127_4840965_11 Belongs to the UPF0173 family - - - 0.0000000000000000000000000006875 123.0
SHD2_k127_4840965_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 406.0
SHD2_k127_4840965_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 408.0
SHD2_k127_4840965_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 287.0
SHD2_k127_4840965_5 Stf0 sulphotransferase K21014 - 2.8.2.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000251 261.0
SHD2_k127_4840965_6 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000294 224.0
SHD2_k127_4840965_7 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000004562 221.0
SHD2_k127_4840965_8 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000003223 191.0
SHD2_k127_4840965_9 DinB superfamily - - - 0.00000000000000000000000000000000000000000002698 167.0
SHD2_k127_4843967_0 Protein of unknown function, DUF255 K06888 - - 6.517e-219 698.0
SHD2_k127_4843967_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 495.0
SHD2_k127_4843967_2 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 454.0
SHD2_k127_4843967_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 384.0
SHD2_k127_4843967_4 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 317.0
SHD2_k127_4880271_0 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 551.0
SHD2_k127_4880271_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 469.0
SHD2_k127_4880271_2 - - - - 0.00000000000000000000000000000000001059 147.0
SHD2_k127_4880271_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000004233 123.0
SHD2_k127_4880271_4 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000001143 120.0
SHD2_k127_4880271_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000004415 100.0
SHD2_k127_4883648_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 1.055e-217 707.0
SHD2_k127_4883648_1 ethanolamine catabolic process K04024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 348.0
SHD2_k127_4883648_10 - - - - 0.000003644 54.0
SHD2_k127_4883648_2 Aldehyde dehydrogenase family K00132 - 1.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 336.0
SHD2_k127_4883648_3 ethanolamine catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 324.0
SHD2_k127_4883648_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 323.0
SHD2_k127_4883648_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 293.0
SHD2_k127_4883648_6 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000009289 198.0
SHD2_k127_4883648_7 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000008493 169.0
SHD2_k127_4883648_8 ethanolamine catabolic process K04027 - - 0.00000000000000000000000000000000000000003625 153.0
SHD2_k127_4883648_9 ethanolamine catabolic process K04019,K04030 - - 0.000000000000000000000000000003694 126.0
SHD2_k127_4898218_0 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001478 266.0
SHD2_k127_4898218_1 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000005975 235.0
SHD2_k127_4898218_10 zinc-ribbon domain - - - 0.00009794 52.0
SHD2_k127_4898218_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000004395 229.0
SHD2_k127_4898218_3 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000001335 219.0
SHD2_k127_4898218_4 - - - - 0.000000000000000000000001 119.0
SHD2_k127_4898218_5 Protein tyrosine kinase - - - 0.000000000000000000000001833 111.0
SHD2_k127_4898218_6 Pentapeptide repeats (9 copies) - - - 0.00000000000000000001646 106.0
SHD2_k127_4898218_7 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000001071 81.0
SHD2_k127_4898218_8 cAMP-dependent protein kinase regulator activity K04739 GO:0000003,GO:0000166,GO:0000187,GO:0000226,GO:0000280,GO:0001704,GO:0001707,GO:0001932,GO:0001933,GO:0001934,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003006,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0005952,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006469,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007049,GO:0007143,GO:0007154,GO:0007162,GO:0007163,GO:0007165,GO:0007267,GO:0007268,GO:0007274,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007369,GO:0007389,GO:0007498,GO:0007507,GO:0007591,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007635,GO:0008103,GO:0008150,GO:0008152,GO:0008283,GO:0008285,GO:0008306,GO:0008355,GO:0008603,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0009994,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0010721,GO:0010738,GO:0010927,GO:0010948,GO:0014706,GO:0014855,GO:0015630,GO:0016020,GO:0016043,GO:0016310,GO:0016325,GO:0017076,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0021700,GO:0022402,GO:0022407,GO:0022408,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030029,GO:0030036,GO:0030104,GO:0030154,GO:0030155,GO:0030234,GO:0030239,GO:0030291,GO:0030435,GO:0030551,GO:0030552,GO:0030554,GO:0030587,GO:0030951,GO:0030952,GO:0031032,GO:0031154,GO:0031156,GO:0031285,GO:0031288,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031594,GO:0031625,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032878,GO:0032944,GO:0032945,GO:0032989,GO:0032991,GO:0033002,GO:0033043,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035265,GO:0035556,GO:0036094,GO:0036211,GO:0040007,GO:0040020,GO:0042048,GO:0042060,GO:0042127,GO:0042129,GO:0042130,GO:0042221,GO:0042303,GO:0042325,GO:0042326,GO:0042327,GO:0042493,GO:0042592,GO:0042692,GO:0042802,GO:0042995,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043434,GO:0043549,GO:0043900,GO:0043901,GO:0043934,GO:0043949,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044853,GO:0045121,GO:0045202,GO:0045214,GO:0045471,GO:0045595,GO:0045596,GO:0045786,GO:0045835,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046006,GO:0046007,GO:0046677,GO:0048285,GO:0048332,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048520,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048598,GO:0048599,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0048871,GO:0048878,GO:0050670,GO:0050672,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050817,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051321,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051447,GO:0051703,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0055001,GO:0055002,GO:0055017,GO:0060038,GO:0060255,GO:0060259,GO:0060281,GO:0060283,GO:0060284,GO:0060419,GO:0060537,GO:0061061,GO:0061695,GO:0061939,GO:0065007,GO:0065008,GO:0065009,GO:0070663,GO:0070664,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071902,GO:0071944,GO:0072359,GO:0072375,GO:0080090,GO:0090036,GO:0090038,GO:0090702,GO:0097159,GO:0097305,GO:0097367,GO:0097435,GO:0097546,GO:0098589,GO:0098590,GO:0098772,GO:0098805,GO:0098857,GO:0098916,GO:0099120,GO:0099536,GO:0099537,GO:0120025,GO:0120038,GO:0140013,GO:1900193,GO:1900194,GO:1901265,GO:1901363,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902531,GO:1902532,GO:1902533,GO:1902911,GO:1903037,GO:1903038,GO:1903046,GO:1903429,GO:1903430,GO:1903506,GO:1903538,GO:1905879,GO:1905880,GO:1990234,GO:2000112,GO:2000114,GO:2000241,GO:2000242,GO:2000253,GO:2000479,GO:2000480,GO:2001141 - 0.000000000000002679 81.0
SHD2_k127_4909298_0 cobalamin binding - - - 2.385e-268 837.0
SHD2_k127_4909298_1 glycoside hydrolase family 37 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 418.0
SHD2_k127_4909298_2 transferase activity, transferring glycosyl groups K21369 - 2.4.1.270 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 401.0
SHD2_k127_4909298_3 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 383.0
SHD2_k127_4909298_5 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.0000000000000000000000002332 110.0
SHD2_k127_4934375_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 3.589e-230 726.0
SHD2_k127_4934375_1 PFAM membrane-flanked domain - - - 0.00000000000000000000000000000000000000000000000000002445 195.0
SHD2_k127_4934375_2 Putative regulatory protein - - - 0.000000000000000000000000000000000000003561 149.0
SHD2_k127_4934375_3 lysyltransferase activity K07027 - - 0.00000000000000000008638 99.0
SHD2_k127_4937717_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 327.0
SHD2_k127_4937717_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 291.0
SHD2_k127_4937717_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006121 250.0
SHD2_k127_4937717_3 histidine kinase A domain protein K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005981 254.0
SHD2_k127_4937717_4 - - - - 0.0000000000000000000000000000000000000000000000000000000006404 209.0
SHD2_k127_4949661_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000005201 200.0
SHD2_k127_4963591_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 479.0
SHD2_k127_4963591_1 Membrane protein involved in D-alanine export K03739,K19294 - - 0.0000000000000000000000000000000000000000000000000008224 201.0
SHD2_k127_498395_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 588.0
SHD2_k127_498395_1 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 500.0
SHD2_k127_498395_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 403.0
SHD2_k127_5007681_0 Domain of unknown function (DUF5110) K01811 - 3.2.1.177 0.0 1127.0
SHD2_k127_5007681_1 alpha-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000002898 226.0
SHD2_k127_5014813_0 Glucuronate isomerase K01812 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 618.0
SHD2_k127_5014813_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 308.0
SHD2_k127_5014813_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000003039 238.0
SHD2_k127_5014813_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.00000000000000000000004654 99.0
SHD2_k127_5014813_4 tagaturonate epimerase K21619 - 5.1.2.7 0.0000122 48.0
SHD2_k127_5018810_0 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 553.0
SHD2_k127_5018810_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K19969 - 4.2.3.152 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 488.0
SHD2_k127_5018810_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000001116 261.0
SHD2_k127_5018810_3 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000007959 214.0
SHD2_k127_5018810_4 S-ribosylhomocysteine lyase activity K07173 GO:0008150,GO:0043900,GO:0043901,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900191,GO:1900231,GO:1900232 4.4.1.21 0.00000000000000000000000000000000000000000000000000000008035 199.0
SHD2_k127_5026146_0 transposition K07497 - - 0.00000000000000000000000000000000000002878 148.0
SHD2_k127_5026146_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000008905 157.0
SHD2_k127_5026146_2 Transposase IS200 like K07491 - - 0.00002135 48.0
SHD2_k127_5035735_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002635 251.0
SHD2_k127_5035735_1 PFAM DinB family protein - - - 0.0000000000000000000000000000000000000000005927 168.0
SHD2_k127_5035735_2 Protein of unknown function (DUF1361) - - - 0.00000000000000000000000000000000000005158 151.0
SHD2_k127_5035735_3 Protein of unknown function (DUF1361) - - - 0.0000000000000000000000000000000000001731 151.0
SHD2_k127_5035735_4 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000002377 97.0
SHD2_k127_5047776_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 500.0
SHD2_k127_5047776_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000006544 74.0
SHD2_k127_505123_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 340.0
SHD2_k127_505123_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007783 278.0
SHD2_k127_505123_2 Acyltransferase family - - - 0.0000000001528 64.0
SHD2_k127_5100005_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 514.0
SHD2_k127_5100005_1 SAF K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 432.0
SHD2_k127_5100005_2 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 298.0
SHD2_k127_5100005_3 Domain of unknown function (DUF4260) - - - 0.00000000000000000000000000000000000001977 147.0
SHD2_k127_5100005_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000001234 83.0
SHD2_k127_5100005_5 helix_turn_helix, mercury resistance - - - 0.0005491 44.0
SHD2_k127_5130691_0 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 618.0
SHD2_k127_5130691_1 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 495.0
SHD2_k127_5130691_2 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 422.0
SHD2_k127_5130691_3 Transcriptional regulator - - - 0.000000000000000000004087 99.0
SHD2_k127_5130691_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000005947 74.0
SHD2_k127_513823_0 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 343.0
SHD2_k127_513823_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 321.0
SHD2_k127_513823_10 LysM domain K21449,K22278 - 3.5.1.104 0.00000000000000000000003883 109.0
SHD2_k127_513823_2 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000001171 262.0
SHD2_k127_513823_3 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001104 266.0
SHD2_k127_513823_4 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000006918 226.0
SHD2_k127_513823_5 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000001942 205.0
SHD2_k127_513823_6 - - - - 0.000000000000000000000000000000000000000000000000000000002708 202.0
SHD2_k127_513823_7 - - - - 0.0000000000000000000000000000000000000000000000000000004281 200.0
SHD2_k127_513823_8 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000161 164.0
SHD2_k127_513823_9 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000001893 114.0
SHD2_k127_5143916_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 2.477e-215 678.0
SHD2_k127_5143916_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 501.0
SHD2_k127_5143916_2 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000009317 174.0
SHD2_k127_5143916_3 helix_turn_helix, arabinose operon control protein K21701 - - 0.0000000000000000000000000000000000000000000001337 171.0
SHD2_k127_515014_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 1.134e-195 618.0
SHD2_k127_515014_1 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 634.0
SHD2_k127_515014_2 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 317.0
SHD2_k127_515014_3 Flavodoxin-like fold K00355 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 287.0
SHD2_k127_515014_4 - - - - 0.000000000002524 70.0
SHD2_k127_5150585_0 aldo keto reductase - - - 0.0000000000000000000000000000000000000000001855 165.0
SHD2_k127_5150585_1 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000001484 131.0
SHD2_k127_5150585_2 Predicted membrane protein (DUF2142) - - - 0.00000000000000001808 95.0
SHD2_k127_5151563_0 Alpha amylase, catalytic domain - - - 5.651e-320 1005.0
SHD2_k127_5151563_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 513.0
SHD2_k127_5151563_2 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 425.0
SHD2_k127_5151563_3 PFAM major facilitator superfamily MFS_1 K08162 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 353.0
SHD2_k127_5151563_4 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 308.0
SHD2_k127_5151563_5 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 0.0000000000000000000000000000000000988 135.0
SHD2_k127_5151563_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000004068 134.0
SHD2_k127_5157742_0 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000000000001851 150.0
SHD2_k127_5157742_1 PFAM DinB family protein - - - 0.000000000000000000000000000002334 126.0
SHD2_k127_5161270_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 532.0
SHD2_k127_5161270_1 HhH-GPD family K03575 - - 0.000000000000000000000000000000000000000000000000001463 190.0
SHD2_k127_5223994_1 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 526.0
SHD2_k127_5223994_2 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 489.0
SHD2_k127_5223994_3 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006961 282.0
SHD2_k127_5223994_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000001578 200.0
SHD2_k127_5223994_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000236 196.0
SHD2_k127_5223994_6 Protein of unknown function (DUF1461) - - - 0.000000000000000000000000000000000000000000000006994 180.0
SHD2_k127_5223994_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.00003453 51.0
SHD2_k127_5223994_8 protein conserved in bacteria - - - 0.00003689 53.0
SHD2_k127_5224173_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 385.0
SHD2_k127_5224173_1 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000001244 219.0
SHD2_k127_5224173_2 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000003968 211.0
SHD2_k127_5224173_3 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000000000000000002196 130.0
SHD2_k127_5224173_4 serine threonine protein kinase - - - 0.0000000552 63.0
SHD2_k127_5248758_0 - K07138 - - 2.106e-197 621.0
SHD2_k127_5248758_1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000001646 140.0
SHD2_k127_5248758_2 F420H(2)-dependent quinone reductase - - - 0.0000000000001472 72.0
SHD2_k127_5259568_0 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 3.645e-281 878.0
SHD2_k127_5259568_1 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 3.959e-237 749.0
SHD2_k127_5259568_2 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 304.0
SHD2_k127_5259568_3 TrkA-N domain K03499,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001071 257.0
SHD2_k127_5259568_4 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000252 257.0
SHD2_k127_5259568_5 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000008151 90.0
SHD2_k127_5259568_6 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001599 87.0
SHD2_k127_5281831_0 PFAM homogentisate 12-dioxygenase K00451 - 1.13.11.5 4.824e-199 625.0
SHD2_k127_5281831_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 383.0
SHD2_k127_5285346_0 Voltage gated chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 375.0
SHD2_k127_5285346_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000004285 228.0
SHD2_k127_5285346_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000008417 208.0
SHD2_k127_5288958_0 DNA restriction-modification system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 384.0
SHD2_k127_5288958_1 - - - - 0.00000000000001009 80.0
SHD2_k127_5295818_0 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity K01954,K01955,K03660,K11540,K11541,K19656 GO:0000050,GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003922,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006142,GO:0006206,GO:0006207,GO:0006220,GO:0006244,GO:0006259,GO:0006281,GO:0006282,GO:0006284,GO:0006285,GO:0006289,GO:0006304,GO:0006355,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0008652,GO:0009056,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009166,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009889,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010605,GO:0016020,GO:0016021,GO:0016053,GO:0016363,GO:0016604,GO:0016607,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019104,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019627,GO:0019637,GO:0019692,GO:0019752,GO:0019856,GO:0031224,GO:0031323,GO:0031324,GO:0031326,GO:0031974,GO:0031981,GO:0032356,GO:0032357,GO:0032991,GO:0033554,GO:0033683,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045007,GO:0045008,GO:0045738,GO:0045934,GO:0045984,GO:0046112,GO:0046386,GO:0046394,GO:0046434,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0051716,GO:0055086,GO:0060255,GO:0062012,GO:0062014,GO:0065007,GO:0070013,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0072529,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901135,GO:1901136,GO:1901291,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2000779,GO:2000780,GO:2001020,GO:2001021,GO:2001141 2.1.3.2,3.5.2.3,4.2.99.18,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 417.0
SHD2_k127_5295818_1 Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase K11540 GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905 2.1.3.2,3.5.2.3,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 357.0
SHD2_k127_5295818_2 DMT(Drug metabolite transporter) superfamily permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 358.0
SHD2_k127_5295818_3 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005313 278.0
SHD2_k127_5295818_4 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000271 223.0
SHD2_k127_5295818_5 cog cog3323 - - - 0.000000000000000000000000000000000000007633 147.0
SHD2_k127_5295818_7 - - - - 0.00000002611 65.0
SHD2_k127_5298694_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 380.0
SHD2_k127_5298694_1 Lipid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 326.0
SHD2_k127_5298694_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000001304 216.0
SHD2_k127_5298694_4 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000008239 203.0
SHD2_k127_5298694_6 transferase activity, transferring glycosyl groups K00754 - - 0.000000003588 59.0
SHD2_k127_5300857_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 597.0
SHD2_k127_5300857_1 conserved protein (DUF2156) K14205 - 2.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 581.0
SHD2_k127_5300857_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 346.0
SHD2_k127_5300857_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000000000001608 143.0
SHD2_k127_5300857_4 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000001293 147.0
SHD2_k127_5300857_5 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000001654 106.0
SHD2_k127_5300857_6 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0000000000000000000659 102.0
SHD2_k127_5302295_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 481.0
SHD2_k127_5302295_1 Flavin-binding monooxygenase-like K07222,K18277 - 1.14.13.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 413.0
SHD2_k127_5302295_10 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000000000000000001924 158.0
SHD2_k127_5302295_11 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000003312 116.0
SHD2_k127_5302295_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 407.0
SHD2_k127_5302295_3 Bacitracin ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 327.0
SHD2_k127_5302295_4 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 320.0
SHD2_k127_5302295_5 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 311.0
SHD2_k127_5302295_6 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 291.0
SHD2_k127_5302295_7 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000195 232.0
SHD2_k127_5302295_8 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000006839 232.0
SHD2_k127_5302295_9 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000004974 153.0
SHD2_k127_5303031_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 593.0
SHD2_k127_5303031_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 527.0
SHD2_k127_5303031_10 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000002686 180.0
SHD2_k127_5303031_11 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000003986 128.0
SHD2_k127_5303031_12 Domain of unknown function DUF11 - - - 0.0000000000000000000000000003087 116.0
SHD2_k127_5303031_13 - - - - 0.00001435 52.0
SHD2_k127_5303031_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 502.0
SHD2_k127_5303031_3 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 441.0
SHD2_k127_5303031_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 357.0
SHD2_k127_5303031_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 307.0
SHD2_k127_5303031_6 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 303.0
SHD2_k127_5303031_7 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 297.0
SHD2_k127_5303031_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004636 257.0
SHD2_k127_5303031_9 - - - - 0.00000000000000000000000000000000000000000000000000000003038 205.0
SHD2_k127_5313666_0 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 9.316e-294 926.0
SHD2_k127_5313666_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000009146 221.0
SHD2_k127_5313666_2 - K08223 - - 0.000000000000000000000000000000000000005493 163.0
SHD2_k127_5313666_3 TIGRFAM primosome, DnaD subunit - - - 0.000000000000000000000000000000000001384 144.0
SHD2_k127_5320231_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 522.0
SHD2_k127_5320231_1 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000004674 183.0
SHD2_k127_5320231_2 Smr domain - - - 0.00000000000000000000000000001707 119.0
SHD2_k127_5325272_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1097.0
SHD2_k127_5325272_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 481.0
SHD2_k127_5325272_2 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 295.0
SHD2_k127_5325272_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000001468 207.0
SHD2_k127_5325272_4 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000001848 151.0
SHD2_k127_5325272_5 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000002125 115.0
SHD2_k127_5325272_6 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000005708 109.0
SHD2_k127_532718_0 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 345.0
SHD2_k127_532718_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 334.0
SHD2_k127_532718_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 292.0
SHD2_k127_532718_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004346 253.0
SHD2_k127_532718_4 NurA - - - 0.00000000000000000000000000000000000000000000000000000000000000000001048 248.0
SHD2_k127_532718_5 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000002235 176.0
SHD2_k127_532718_6 YhhN family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000002544 106.0
SHD2_k127_5327955_0 Transcriptional activator domain - - - 5.762e-200 661.0
SHD2_k127_5327955_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 396.0
SHD2_k127_5327955_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01476,K01480 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 366.0
SHD2_k127_5327955_3 Response regulator, receiver K02487,K03407,K03413,K06596,K11526,K13490 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001141 276.0
SHD2_k127_5327955_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000007293 259.0
SHD2_k127_5327955_5 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000003284 229.0
SHD2_k127_5327955_6 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000001708 121.0
SHD2_k127_5330312_0 Oxidoreductase family, C-terminal alpha/beta domain K13016 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 435.0
SHD2_k127_5330312_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 436.0
SHD2_k127_5330312_2 transferase hexapeptide K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001724 275.0
SHD2_k127_5330312_3 Glycosyl transferases group 1 - - - 0.0000004084 53.0
SHD2_k127_5330312_4 Transport permease protein K09690 - - 0.0002298 44.0
SHD2_k127_5353497_0 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 412.0
SHD2_k127_5353497_1 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000001255 221.0
SHD2_k127_5353770_0 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 356.0
SHD2_k127_5353770_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 313.0
SHD2_k127_5353770_2 spore germination K03298 - - 0.0000000000000000000000000000000000000000000000000000000000000004566 230.0
SHD2_k127_5353770_3 Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring K18816 - 2.3.1.82 0.00000000000000000000000000000000005356 140.0
SHD2_k127_5353770_4 Protein of unknown function (DUF1275) - - - 0.0000000000000000000000000000000002234 136.0
SHD2_k127_5353770_5 methyltransferase activity - - - 0.00000000000000000009917 90.0
SHD2_k127_5353770_6 methyltransferase activity - - - 0.000008278 48.0
SHD2_k127_536802_0 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 380.0
SHD2_k127_536802_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 365.0
SHD2_k127_536802_2 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 293.0
SHD2_k127_536802_3 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000000000008618 187.0
SHD2_k127_536802_4 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000000000000000001368 166.0
SHD2_k127_5374850_0 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000002361 216.0
SHD2_k127_5374850_1 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000007058 190.0
SHD2_k127_5374850_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000001667 199.0
SHD2_k127_5374850_3 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000007773 121.0
SHD2_k127_5376725_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1335.0
SHD2_k127_5376725_1 Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine K05830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 327.0
SHD2_k127_5376725_2 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000000001432 133.0
SHD2_k127_5376725_3 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000002114 79.0
SHD2_k127_5382710_0 PFAM amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 589.0
SHD2_k127_5382710_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000001847 255.0
SHD2_k127_5382710_2 Protein of unknown function (DUF429) - - - 0.00000000000000000000000000000000000000000000000000000000000004535 220.0
SHD2_k127_5382710_3 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000000000000001375 154.0
SHD2_k127_5382710_4 PFAM response regulator receiver K02282 - - 0.0000000000000000000000004689 114.0
SHD2_k127_5430825_0 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001678 250.0
SHD2_k127_5430825_1 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000002207 228.0
SHD2_k127_5430825_2 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002809 145.0
SHD2_k127_5430825_3 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000002368 123.0
SHD2_k127_5430825_4 Tissue inhibitor of metalloproteinase - - - 0.00000000000000000002011 100.0
SHD2_k127_5430825_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000131 86.0
SHD2_k127_5430825_6 - - - - 0.000000000000001155 79.0
SHD2_k127_5430825_7 Belongs to the UPF0109 family K06960 - - 0.00005131 46.0
SHD2_k127_5434473_0 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 434.0
SHD2_k127_5434473_1 polysaccharide deacetylase K01406 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 342.0
SHD2_k127_5439113_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000001445 194.0
SHD2_k127_5439113_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000006973 177.0
SHD2_k127_5439113_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000001826 171.0
SHD2_k127_5439295_0 TIGRFAM dihydroxyacetone kinase, DhaK subunit K05878 - 2.7.1.121 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 584.0
SHD2_k127_5439295_1 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 469.0
SHD2_k127_5439295_2 TIGRFAM dihydroxyacetone kinase, L subunit K05879 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003712 280.0
SHD2_k127_5439295_3 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 - 2.1.1.182,2.1.1.184 0.000000000000007149 81.0
SHD2_k127_5450771_0 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000005975 168.0
SHD2_k127_5450771_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000008281 132.0
SHD2_k127_5450771_2 - - - - 0.000000000000008507 76.0
SHD2_k127_5454498_0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 569.0
SHD2_k127_5454498_1 hydrolase activity, hydrolyzing O-glycosyl compounds K00690 - 2.4.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 412.0
SHD2_k127_5454498_2 cobalamin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000171 225.0
SHD2_k127_5459466_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 1.75e-312 970.0
SHD2_k127_5459466_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 5.758e-268 837.0
SHD2_k127_5459466_3 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000004661 174.0
SHD2_k127_5459466_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000001694 163.0
SHD2_k127_5459466_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000003844 144.0
SHD2_k127_5459466_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000002526 135.0
SHD2_k127_5487557_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 481.0
SHD2_k127_5487557_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000004881 231.0
SHD2_k127_5487557_2 TIGRFAM channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000000000001532 199.0
SHD2_k127_5487557_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000004476 178.0
SHD2_k127_5487557_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000007994 154.0
SHD2_k127_5487557_5 YsiA-like protein, C-terminal region - - - 0.000000000000000000000000000000000001188 147.0
SHD2_k127_5487557_6 - - - - 0.00000000000000000000000000004442 122.0
SHD2_k127_5487557_7 gas vesicle protein - - - 0.0000000000000000000789 94.0
SHD2_k127_5493582_0 Aminotransferase class-III K15372 - 2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 468.0
SHD2_k127_5493582_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000003464 217.0
SHD2_k127_5493582_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000003845 112.0
SHD2_k127_5493582_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000007075 114.0
SHD2_k127_5493582_4 hydrolase family 20, catalytic K12373 - 3.2.1.52 0.0000000000000000000000005489 105.0
SHD2_k127_5499118_0 ABC transporter transmembrane region K06147 - - 5.374e-248 780.0
SHD2_k127_5499118_1 ABC transporter transmembrane region K06147 - - 8.296e-241 758.0
SHD2_k127_5499118_10 Peptidase_C39 like family - - - 0.000005543 51.0
SHD2_k127_5499118_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 464.0
SHD2_k127_5499118_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 438.0
SHD2_k127_5499118_4 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 423.0
SHD2_k127_5499118_5 ABC transporter permease K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 413.0
SHD2_k127_5499118_6 drug transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 405.0
SHD2_k127_5499118_7 SpoU rRNA Methylase family K03218,K03437,K21514 - 2.1.1.185,2.1.1.208 0.00000000000000000000000000000000000000000000000000000000000000000000000000231 261.0
SHD2_k127_5499118_8 -acetyltransferase - - - 0.00000000000000000000000000000000000000000001894 172.0
SHD2_k127_5499118_9 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000002115 108.0
SHD2_k127_5499290_0 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 578.0
SHD2_k127_5499290_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 561.0
SHD2_k127_5499290_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 424.0
SHD2_k127_5499290_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000003464 239.0
SHD2_k127_5499290_4 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000308 188.0
SHD2_k127_5499290_5 - - - - 0.00000000000000000000000000000000000000000001164 165.0
SHD2_k127_5499290_6 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000000000001043 174.0
SHD2_k127_5499290_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000003894 116.0
SHD2_k127_5499290_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000000000000000001873 110.0
SHD2_k127_5499290_9 pathogenesis K01447,K21471 - 3.5.1.28 0.00000000004357 74.0
SHD2_k127_5501782_0 Phosphotransferase enzyme family K18844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 311.0
SHD2_k127_5501782_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002551 255.0
SHD2_k127_5501782_2 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000001269 203.0
SHD2_k127_5501782_3 InterPro IPR014922 - - - 0.00000000000000000000000000000000000000000000002189 174.0
SHD2_k127_5501782_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000003291 167.0
SHD2_k127_5501782_5 DinB family - - - 0.0000000000000000000000000000000000000001007 153.0
SHD2_k127_5501782_6 YCII-related domain - - - 0.00000000000000000000000000003384 120.0
SHD2_k127_5527448_0 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 323.0
SHD2_k127_5527448_1 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 336.0
SHD2_k127_5527448_2 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000001961 253.0
SHD2_k127_5527448_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000002542 145.0
SHD2_k127_5527448_4 Domain of unknown function (DUF4349) - - - 0.000000000009106 69.0
SHD2_k127_555393_0 Alpha-amylase domain K01182,K01187 - 3.2.1.10,3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 516.0
SHD2_k127_555393_1 Domain of unknown function (DUF3520) K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 469.0
SHD2_k127_555393_2 Baseplate J-like protein K01218 - 3.2.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000001168 269.0
SHD2_k127_555393_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000001497 151.0
SHD2_k127_5603506_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.785e-301 936.0
SHD2_k127_5603506_1 stress-induced mitochondrial fusion - - - 7.659e-272 850.0
SHD2_k127_5603506_10 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000001755 145.0
SHD2_k127_5603506_11 Involved in the tonB-independent uptake of proteins K01771 - 4.6.1.13 0.00000000000000000000000000000000001073 153.0
SHD2_k127_5603506_12 RNA polymerase, sigma-24 subunit, ECF subfamily - - - 0.00000000000000000000000000000000007056 139.0
SHD2_k127_5603506_13 WD-40 repeat - - - 0.000000000000000000001667 108.0
SHD2_k127_5603506_14 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000001697 89.0
SHD2_k127_5603506_15 - - - - 0.000000000000000000516 96.0
SHD2_k127_5603506_17 Putative zinc-finger - - - 0.000000004182 65.0
SHD2_k127_5603506_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 477.0
SHD2_k127_5603506_3 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 336.0
SHD2_k127_5603506_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002796 269.0
SHD2_k127_5603506_5 Protein of unknown function (DUF981) K08980 - - 0.000000000000000000000000000000000000000000000000000000000000000647 224.0
SHD2_k127_5603506_6 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001815 203.0
SHD2_k127_5603506_8 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000002372 174.0
SHD2_k127_5603506_9 Ribosomal protein L11 methyltransferase (PrmA) K05929 - 2.1.1.103 0.0000000000000000000000000000000000000009926 156.0
SHD2_k127_5634508_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 9.602e-287 889.0
SHD2_k127_5634508_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 554.0
SHD2_k127_5634508_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 530.0
SHD2_k127_5634508_3 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000002082 158.0
SHD2_k127_5634508_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000003722 116.0
SHD2_k127_5634508_5 Histidine Phosphotransfer domain - - - 0.000000000000000000000000001589 119.0
SHD2_k127_5634508_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000007068 82.0
SHD2_k127_5644321_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2059.0
SHD2_k127_5644321_1 PFAM major facilitator superfamily MFS_1 K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 478.0
SHD2_k127_5644321_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001035 245.0
SHD2_k127_5644321_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001283 212.0
SHD2_k127_5644321_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000005204 164.0
SHD2_k127_5653229_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 359.0
SHD2_k127_5653229_1 - - - - 0.00000000000000000000000000000000000000000000007997 173.0
SHD2_k127_5653489_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.362e-221 696.0
SHD2_k127_5653489_1 Aminotransferase class-III K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 542.0
SHD2_k127_5653489_10 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000386 51.0
SHD2_k127_5653489_11 Phosphopantetheine attachment site - - - 0.000006201 51.0
SHD2_k127_5653489_2 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821,K05830,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 533.0
SHD2_k127_5653489_3 Psort location Cytoplasmic, score 8.87 K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 486.0
SHD2_k127_5653489_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 383.0
SHD2_k127_5653489_5 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 394.0
SHD2_k127_5653489_6 PFAM RNA binding S1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000004328 225.0
SHD2_k127_5653489_7 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000005515 136.0
SHD2_k127_5653489_8 Transcription regulator K03718 - - 0.00000000000000000000000000000004593 131.0
SHD2_k127_5653489_9 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000417 83.0
SHD2_k127_5660035_0 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 590.0
SHD2_k127_5660035_1 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 317.0
SHD2_k127_5660035_2 peptidase M24 K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006337 274.0
SHD2_k127_5660035_3 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000001263 152.0
SHD2_k127_5660035_4 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000002549 119.0
SHD2_k127_5711015_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1168.0
SHD2_k127_5711015_1 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 336.0
SHD2_k127_5711015_10 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00001338 58.0
SHD2_k127_5711015_2 Leucine Rich Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001669 273.0
SHD2_k127_5711015_3 Catechol dioxygenase N terminus K03381 - 1.13.11.1 0.0000000000000000000000000000000000000000000000000000000008949 209.0
SHD2_k127_5711015_5 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000165 183.0
SHD2_k127_5711015_6 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000002755 179.0
SHD2_k127_5711015_7 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000002251 144.0
SHD2_k127_5711015_8 metallopeptidase activity K20276 - - 0.00000000000000000001157 107.0
SHD2_k127_5711015_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.000002522 55.0
SHD2_k127_5715775_0 Class II Aldolase and Adducin N-terminal domain K01845 - 5.4.3.8 6.398e-217 681.0
SHD2_k127_5715775_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 493.0
SHD2_k127_5715775_2 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000006333 237.0
SHD2_k127_5715775_3 Sodium bile acid symporter family protein K03453 - - 0.000000000000000000000000000000000000000000000000000000001768 211.0
SHD2_k127_5715775_4 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000001093 146.0
SHD2_k127_5715775_5 transmembrane transporter activity - - - 0.00000000000000000000000002543 109.0
SHD2_k127_5744776_0 ATPase activity K02045 - 3.6.3.25 9.111e-217 690.0
SHD2_k127_5744776_1 PFAM Pyridoxal-dependent decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 599.0
SHD2_k127_5744776_10 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 312.0
SHD2_k127_5744776_11 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000004495 263.0
SHD2_k127_5744776_12 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000001321 170.0
SHD2_k127_5744776_13 - - - - 0.0000000000000000000000000000000000000002896 156.0
SHD2_k127_5744776_14 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000002569 143.0
SHD2_k127_5744776_15 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000003036 141.0
SHD2_k127_5744776_16 - - - - 0.00000000000000000000000000000000002833 149.0
SHD2_k127_5744776_17 nitrate reductase activity - - - 0.0000000000000000000000000000000425 133.0
SHD2_k127_5744776_18 Squalene/phytoene synthase K00801 - 2.5.1.21 0.0000000000000000000000000000001868 136.0
SHD2_k127_5744776_19 Major Facilitator Superfamily - - - 0.0000000000000000000000001864 113.0
SHD2_k127_5744776_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 521.0
SHD2_k127_5744776_20 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000001234 109.0
SHD2_k127_5744776_21 Sulfurtransferase TusA - - - 0.000000000000000003646 86.0
SHD2_k127_5744776_22 efflux transmembrane transporter activity K02004 - - 0.0000002031 63.0
SHD2_k127_5744776_3 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 477.0
SHD2_k127_5744776_4 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 437.0
SHD2_k127_5744776_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 389.0
SHD2_k127_5744776_6 ATPase-coupled sulfate transmembrane transporter activity K02046,K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 359.0
SHD2_k127_5744776_7 phosphate transport system permease protein K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 334.0
SHD2_k127_5744776_8 ATPase-coupled sulfate transmembrane transporter activity K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 325.0
SHD2_k127_5744776_9 phosphate ion binding K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 317.0
SHD2_k127_5776026_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 310.0
SHD2_k127_5776026_1 ABC transporter K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 296.0
SHD2_k127_5776026_2 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 291.0
SHD2_k127_5776026_3 ABC transporter, permease protein K02029,K02030,K09971,K17062 - - 0.00000000000000000000000000000000000000000000000000000000008741 214.0
SHD2_k127_5776026_4 amino acid transport K02030 - - 0.000000000000000000000000000000000000000000000000000154 198.0
SHD2_k127_5776026_5 SCP-2 sterol transfer family - - - 0.00000000000000000000000000173 116.0
SHD2_k127_578196_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 323.0
SHD2_k127_5785083_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.06e-221 709.0
SHD2_k127_5785083_1 N-terminal 7TM region of histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 574.0
SHD2_k127_5785083_10 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005005 267.0
SHD2_k127_5785083_11 PFAM RNA binding S1 domain protein K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001912 275.0
SHD2_k127_5785083_12 NAD-dependent epimerase dehydratase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004843 256.0
SHD2_k127_5785083_13 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000005632 248.0
SHD2_k127_5785083_14 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000002316 176.0
SHD2_k127_5785083_15 - - - - 0.0000000000000000000000000000000000002029 149.0
SHD2_k127_5785083_16 acetyltransferase K06889,K19273 - - 0.00000000000000000000000000000000001786 141.0
SHD2_k127_5785083_17 Belongs to the TPP enzyme family K04103 - 4.1.1.74 0.000001979 49.0
SHD2_k127_5785083_2 response regulator, receiver K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 493.0
SHD2_k127_5785083_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 385.0
SHD2_k127_5785083_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 394.0
SHD2_k127_5785083_5 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 380.0
SHD2_k127_5785083_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 347.0
SHD2_k127_5785083_7 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 322.0
SHD2_k127_5785083_8 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 333.0
SHD2_k127_5785083_9 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006126 284.0
SHD2_k127_5792237_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 327.0
SHD2_k127_5792237_1 PFAM ABC transporter transmembrane region K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001092 271.0
SHD2_k127_5792237_2 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003465 235.0
SHD2_k127_5792237_3 F420H(2)-dependent quinone reductase - - - 0.00000000000008796 77.0
SHD2_k127_5792237_4 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000002126 64.0
SHD2_k127_5792237_5 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000001335 53.0
SHD2_k127_5794491_0 elongation factor Tu domain 2 protein K02355 - - 1.324e-290 909.0
SHD2_k127_5794491_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 520.0
SHD2_k127_5794491_10 TIGRFAM competence protein ComEA helix-hairpin-helix K02237 - - 0.000000000000000000000000000000000009912 142.0
SHD2_k127_5794491_11 JAB/MPN domain - - - 0.00000000000000000000000000002657 124.0
SHD2_k127_5794491_12 COG0526, thiol-disulfide isomerase and thioredoxins K03671 - - 0.0000000000000000000000000002391 122.0
SHD2_k127_5794491_13 ThiS family K03636 - - 0.00000000000000000000002505 102.0
SHD2_k127_5794491_14 ThiS family K03636 - - 0.000000000000006968 78.0
SHD2_k127_5794491_15 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000344 82.0
SHD2_k127_5794491_16 Acetyltransferase (GNAT) domain - - - 0.0000000000752 68.0
SHD2_k127_5794491_2 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 493.0
SHD2_k127_5794491_3 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 404.0
SHD2_k127_5794491_4 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 357.0
SHD2_k127_5794491_5 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009217 265.0
SHD2_k127_5794491_6 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.00000000000000000000000000000000000000000000000000000000005626 212.0
SHD2_k127_5794491_7 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000002011 211.0
SHD2_k127_5794491_8 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000000002974 174.0
SHD2_k127_5794491_9 methyltransferase activity K00569 - 2.1.1.67 0.00000000000000000000000000000000000000001651 160.0
SHD2_k127_5802873_0 Penicillin-Binding Protein C-terminus Family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 607.0
SHD2_k127_5802873_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 358.0
SHD2_k127_5802873_2 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000006021 184.0
SHD2_k127_5802873_3 DMSO reductase anchor subunit (DmsC) K07308 - - 0.00000000000000001722 93.0
SHD2_k127_5854654_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 372.0
SHD2_k127_5854654_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 298.0
SHD2_k127_5854654_10 OsmC-like protein - - - 0.0000000000000000000000000000000004833 136.0
SHD2_k127_5854654_11 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000001979 114.0
SHD2_k127_5854654_12 DGC domain - - - 0.000000000000000000000000002341 116.0
SHD2_k127_5854654_13 4Fe-4S dicluster domain - - - 0.00000000000000000000000005882 114.0
SHD2_k127_5854654_14 Thioredoxin domain - - - 0.0000000000000000000001381 99.0
SHD2_k127_5854654_15 DNA-binding transcription factor activity - - - 0.000000000000000000007252 97.0
SHD2_k127_5854654_16 - - - - 0.000003812 51.0
SHD2_k127_5854654_2 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000006061 194.0
SHD2_k127_5854654_3 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000006238 179.0
SHD2_k127_5854654_4 trisaccharide binding K03556 - - 0.0000000000000000000000000000000000000000000003149 177.0
SHD2_k127_5854654_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000007083 171.0
SHD2_k127_5854654_6 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000008775 172.0
SHD2_k127_5854654_7 Predicted permease - - - 0.000000000000000000000000000000000000006265 154.0
SHD2_k127_5854654_8 DGC domain - - - 0.00000000000000000000000000000000000279 147.0
SHD2_k127_5854654_9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000002103 139.0
SHD2_k127_5862684_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649,K02594 - 2.3.3.13,2.3.3.14 8.646e-212 667.0
SHD2_k127_5862684_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 580.0
SHD2_k127_5862684_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 496.0
SHD2_k127_5862684_3 Alpha beta hydrolase K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 417.0
SHD2_k127_5862684_4 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000002417 179.0
SHD2_k127_5862684_5 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000002219 156.0
SHD2_k127_5862684_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.00000000000000000000000000002623 118.0
SHD2_k127_5878470_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 491.0
SHD2_k127_5878470_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000313 258.0
SHD2_k127_5878470_2 Dual specificity phosphatase, catalytic domain - - - 0.000000005184 63.0
SHD2_k127_5962363_0 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 514.0
SHD2_k127_5962363_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001543 260.0
SHD2_k127_5962363_2 transcription factor binding - - - 0.0000000000000000000000000000000000000000005555 159.0
SHD2_k127_5973421_0 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 364.0
SHD2_k127_6001386_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 480.0
SHD2_k127_6001386_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004862 267.0
SHD2_k127_6001386_2 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000009913 241.0
SHD2_k127_6001386_3 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000002668 243.0
SHD2_k127_6001386_4 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000001014 229.0
SHD2_k127_6001386_5 Rdx family K07401 - - 0.00000000002801 65.0
SHD2_k127_6020682_0 Glycosyl hydrolase family 115 - - - 0.0 1299.0
SHD2_k127_6020682_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 447.0
SHD2_k127_6020682_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001092 279.0
SHD2_k127_6020682_3 Ribosomal RNA adenine dimethylase - - - 0.00000004596 56.0
SHD2_k127_6021185_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 560.0
SHD2_k127_6021185_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 469.0
SHD2_k127_6021185_2 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 430.0
SHD2_k127_6021185_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000002182 73.0
SHD2_k127_6049587_0 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 590.0
SHD2_k127_6049587_1 beta-1,4-mannooligosaccharide phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 512.0
SHD2_k127_6049587_10 - - - - 0.0000001027 61.0
SHD2_k127_6049587_2 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 481.0
SHD2_k127_6049587_3 PFAM Cytochrome P450 - GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 417.0
SHD2_k127_6049587_4 PFAM regulatory protein, MerR K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 361.0
SHD2_k127_6049587_5 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 335.0
SHD2_k127_6049587_6 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001229 263.0
SHD2_k127_6049587_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001193 244.0
SHD2_k127_6049587_8 Membrane K22502 - 5.5.1.19 0.0000000000002729 74.0
SHD2_k127_6049587_9 Transcription factor K07736 - - 0.0000000005485 66.0
SHD2_k127_6060470_0 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 611.0
SHD2_k127_6060470_1 PFAM Monogalactosyldiacylglycerol synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 400.0
SHD2_k127_6060470_2 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001517 282.0
SHD2_k127_6060470_3 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001367 257.0
SHD2_k127_6060470_4 PFAM peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000003465 235.0
SHD2_k127_6060470_5 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000000000000002044 207.0
SHD2_k127_6060470_6 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000002715 156.0
SHD2_k127_6060470_7 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000000000004228 141.0
SHD2_k127_6060470_8 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000005606 88.0
SHD2_k127_6096076_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 390.0
SHD2_k127_6096076_1 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000004495 205.0
SHD2_k127_6096076_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000149 197.0
SHD2_k127_6096076_3 Highly conserved protein containing a thioredoxin domain K18581 - 3.2.1.180 0.000000000000000000000000000000000000000006491 160.0
SHD2_k127_6096076_4 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000001418 164.0
SHD2_k127_6111624_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 566.0
SHD2_k127_6111624_1 Periplasmic binding protein-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 386.0
SHD2_k127_6111624_2 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 361.0
SHD2_k127_6111624_3 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002182 281.0
SHD2_k127_6111624_4 AI-2E family transporter - - - 0.00000000003053 76.0
SHD2_k127_6122446_0 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000003392 171.0
SHD2_k127_6122446_1 dihydroorotate dehydrogenase activity K17828 - 1.3.1.14 0.0000000000000000000000000000000000000008003 158.0
SHD2_k127_6122446_2 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000006826 136.0
SHD2_k127_6122446_3 methyltransferase - - - 0.000006327 51.0
SHD2_k127_620674_0 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 468.0
SHD2_k127_620674_1 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003283 256.0
SHD2_k127_620674_2 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000007083 247.0
SHD2_k127_620674_3 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000001502 224.0
SHD2_k127_6207103_0 PFAM Dak phosphatase K07030 - - 1.884e-219 693.0
SHD2_k127_6207103_1 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 366.0
SHD2_k127_6207103_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 316.0
SHD2_k127_6207103_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004237 252.0
SHD2_k127_6207103_4 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000002794 245.0
SHD2_k127_6207103_5 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000557 156.0
SHD2_k127_6207103_6 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000000004544 134.0
SHD2_k127_6207103_7 - - - - 0.00000000000000000000000000000312 127.0
SHD2_k127_6207103_8 ribosomal protein L28 K02902 - - 0.00000000000000000001014 93.0
SHD2_k127_6207103_9 Nucleotidyltransferase domain K07076 - - 0.000000000000000003064 88.0
SHD2_k127_6211842_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.924e-212 677.0
SHD2_k127_6211842_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 445.0
SHD2_k127_6211842_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006397 252.0
SHD2_k127_6211842_3 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000000000000000000000000008042 207.0
SHD2_k127_6211842_4 iron dependent repressor K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000002141 146.0
SHD2_k127_6211842_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000003972 148.0
SHD2_k127_6211842_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000005669 117.0
SHD2_k127_6211842_7 YHS domain - - - 0.000000000000002874 86.0
SHD2_k127_6211842_8 PFAM FeoA family protein K04758 - - 0.000000004152 61.0
SHD2_k127_6211842_9 methyltransferase K01921 - 6.3.2.4 0.000007203 57.0
SHD2_k127_6224875_0 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006879 271.0
SHD2_k127_6224875_1 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000007498 180.0
SHD2_k127_6224875_2 AntiSigma factor - - - 0.000000000000000000000000000002776 135.0
SHD2_k127_6224875_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000007862 112.0
SHD2_k127_6224875_4 - - - - 0.0000000000002599 75.0
SHD2_k127_622716_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 3.985e-204 643.0
SHD2_k127_622716_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 2.151e-198 627.0
SHD2_k127_622716_2 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 391.0
SHD2_k127_622716_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 343.0
SHD2_k127_622716_4 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 303.0
SHD2_k127_622716_5 PFAM glutamine amidotransferase class-I K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000004797 236.0
SHD2_k127_622716_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000005464 183.0
SHD2_k127_622716_7 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000009137 144.0
SHD2_k127_6245266_0 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 327.0
SHD2_k127_6245266_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 327.0
SHD2_k127_6245266_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 325.0
SHD2_k127_6245266_3 4-vinyl reductase, 4VR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 300.0
SHD2_k127_6245266_4 Domain of unknown function (DUF348) - - - 0.0000000000000000000000000000000000000000000000000000000000000000218 229.0
SHD2_k127_6245266_5 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000000000000000003094 201.0
SHD2_k127_6245266_6 LytR cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000001728 126.0
SHD2_k127_62533_0 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002905 282.0
SHD2_k127_62533_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000003882 209.0
SHD2_k127_62533_3 bleomycin resistance protein - - - 0.0000000000000000000000000000000000001581 146.0
SHD2_k127_62533_4 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.000000000000001478 87.0
SHD2_k127_62533_5 - - - - 0.0000000002991 70.0
SHD2_k127_62533_6 mRNA catabolic process K06950 - - 0.0000001495 60.0
SHD2_k127_62557_0 SMART Elongator protein 3 MiaB NifB - - - 6.908e-221 696.0
SHD2_k127_62557_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 304.0
SHD2_k127_62557_10 -O-antigen K02847 - - 0.00000000000000005435 96.0
SHD2_k127_62557_11 Ig-like domain from next to BRCA1 gene K17987 - - 0.00000000000001335 88.0
SHD2_k127_62557_12 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase - - - 0.000000000001511 75.0
SHD2_k127_62557_13 Involved in the tonB-independent uptake of proteins - - - 0.000000007008 68.0
SHD2_k127_62557_14 Stage V sporulation protein S (SpoVS) K06416 - - 0.000000389 53.0
SHD2_k127_62557_15 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000004438 60.0
SHD2_k127_62557_16 Uridine phosphorylase K00757 - 2.4.2.3 0.0000478 49.0
SHD2_k127_62557_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002268 307.0
SHD2_k127_62557_3 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005558 273.0
SHD2_k127_62557_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003478 263.0
SHD2_k127_62557_5 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001203 274.0
SHD2_k127_62557_6 Integral membrane protein (intg_mem_TP0381) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003301 246.0
SHD2_k127_62557_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000003414 207.0
SHD2_k127_62557_8 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000007883 160.0
SHD2_k127_62557_9 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase - - - 0.0000000000000000004516 91.0
SHD2_k127_629581_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000008457 203.0
SHD2_k127_629581_1 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000001145 94.0
SHD2_k127_630661_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 517.0
SHD2_k127_630661_1 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000001048 218.0
SHD2_k127_630661_2 PFAM ABC transporter related K01990 - - 0.0000000000000004526 81.0
SHD2_k127_6310413_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 5.598e-204 644.0
SHD2_k127_6310413_1 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 585.0
SHD2_k127_6310413_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000009877 226.0
SHD2_k127_6310413_11 transport system permease K01998 - - 0.00000000000000000000000000000000000000000000000000008644 200.0
SHD2_k127_6310413_12 Catalyzes the transfer of electrons from NADH to quinone K00336 - 1.6.5.3 0.000000000000167 81.0
SHD2_k127_6310413_13 binding domain protein K07138 - - 0.000003318 52.0
SHD2_k127_6310413_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 564.0
SHD2_k127_6310413_3 PFAM Aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 563.0
SHD2_k127_6310413_4 FAD binding domain K00481 - 1.14.13.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 506.0
SHD2_k127_6310413_5 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 398.0
SHD2_k127_6310413_6 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 315.0
SHD2_k127_6310413_7 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002673 271.0
SHD2_k127_6310413_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003817 268.0
SHD2_k127_6310413_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000003044 239.0
SHD2_k127_6313150_0 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 561.0
SHD2_k127_6313150_1 PFAM ROK family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 426.0
SHD2_k127_6313150_2 PFAM binding-protein-dependent transport systems inner membrane component K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 366.0
SHD2_k127_6313150_3 PFAM extracellular solute-binding protein family 1 K15770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 330.0
SHD2_k127_6313150_4 EamA-like transporter family - - - 0.000000000000000000001211 96.0
SHD2_k127_6313150_5 PFAM binding-protein-dependent transport systems inner membrane component K15772 - - 0.000000000000000000002958 99.0
SHD2_k127_6328212_0 3-deoxy-manno-octulosonate-8-phosphatase activity K00983,K03270 - 2.7.7.43,3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 483.0
SHD2_k127_6328212_1 NeuB family K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 432.0
SHD2_k127_6328212_2 UDP-N-acetylglucosamine 2-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000457 279.0
SHD2_k127_6328212_3 PFAM Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000005314 199.0
SHD2_k127_6328212_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000003177 137.0
SHD2_k127_6342472_0 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 381.0
SHD2_k127_6342472_1 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000001453 194.0
SHD2_k127_6342472_2 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.0000000000000000000000000000000000000000000000000796 184.0
SHD2_k127_6342472_3 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000000000002072 126.0
SHD2_k127_636371_0 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 333.0
SHD2_k127_636371_1 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 303.0
SHD2_k127_636371_2 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 310.0
SHD2_k127_636371_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001832 256.0
SHD2_k127_636371_4 phospholipase Carboxylesterase K06999 - - 0.000000000000000000000004796 110.0
SHD2_k127_636371_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000001132 58.0
SHD2_k127_6369557_0 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001365 243.0
SHD2_k127_6369557_1 dolichyl monophosphate biosynthetic process - - - 0.000000000000000000001341 97.0
SHD2_k127_6378532_0 PFAM CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 422.0
SHD2_k127_6378532_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000002795 209.0
SHD2_k127_6378532_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00000000000000000000000000000001026 138.0
SHD2_k127_6378532_3 - - - - 0.000000000008288 76.0
SHD2_k127_6378532_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000003752 49.0
SHD2_k127_6378532_5 STAS domain K04749 - - 0.000006541 53.0
SHD2_k127_637955_0 Flavin containing amine oxidoreductase K15745 - 1.3.99.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 345.0
SHD2_k127_637955_1 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004238 242.0
SHD2_k127_637955_2 Cellulase (glycosyl hydrolase family 5) - - - 0.00000000000000000000000000000000000000000000000000000000000002922 218.0
SHD2_k127_637955_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000004869 71.0
SHD2_k127_637955_4 Psort location Cytoplasmic, score 8.96 - - - 0.000007097 54.0
SHD2_k127_6381215_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 316.0
SHD2_k127_6381215_1 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000001909 218.0
SHD2_k127_6381215_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000003157 211.0
SHD2_k127_6381215_5 - - - - 0.0000000000000000000000000001336 121.0
SHD2_k127_6381215_6 Cupin domain - - - 0.0000000000000000000002198 104.0
SHD2_k127_6381215_7 PFAM membrane protein of K08972 - - 0.00000000000000000000269 98.0
SHD2_k127_6381215_8 PFAM Glycoside hydrolase 15-related - - - 0.000001895 60.0
SHD2_k127_6381522_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 474.0
SHD2_k127_6381522_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 447.0
SHD2_k127_6381522_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 306.0
SHD2_k127_6381522_3 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000001833 251.0
SHD2_k127_6381522_4 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000006802 231.0
SHD2_k127_6381522_5 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 - 5.4.99.5 0.000000000000000000000000000000000000000003729 157.0
SHD2_k127_6381522_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.000000000000000000000000000000005045 135.0
SHD2_k127_6396009_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.082e-199 640.0
SHD2_k127_6396009_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006834 277.0
SHD2_k127_6396009_2 4Fe-4S binding domain K14091 - - 0.0000000000000000000000000000000000003707 149.0
SHD2_k127_6396009_3 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000001045 114.0
SHD2_k127_6396009_4 hydrogenase maturation protease K08315 - 3.4.23.51 0.000000000000000000000004761 109.0
SHD2_k127_6397867_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 407.0
SHD2_k127_6397867_1 endonuclease III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 381.0
SHD2_k127_6397867_2 Thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000004715 212.0
SHD2_k127_6397867_3 adenosylhomocysteine nucleosidase activity K01239,K01243,K03716 - 3.2.2.1,3.2.2.9,4.1.99.14 0.0000000000000000000000000000000000000000000000002457 187.0
SHD2_k127_6397867_4 Acetyltransferase (GNAT) domain K03828 - - 0.0000000000000000000000000000000006658 139.0
SHD2_k127_6397867_5 FAD binding domain in molybdopterin dehydrogenase K03519,K12529 - 1.2.5.3 0.000000000000000000003545 99.0
SHD2_k127_6397867_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000008273 94.0
SHD2_k127_6397867_7 SERine Proteinase INhibitors K13963 - - 0.0000000000002467 70.0
SHD2_k127_6397867_8 Lysin motif - - - 0.0004977 53.0
SHD2_k127_6410769_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 508.0
SHD2_k127_6410769_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K03918,K07250,K20428 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 350.0
SHD2_k127_6410769_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003188 269.0
SHD2_k127_6410769_4 Alanine-glyoxylate amino-transferase K00375 - - 0.0000000000000000000001406 103.0
SHD2_k127_6418676_0 MFS/sugar transport protein K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 602.0
SHD2_k127_6418676_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 329.0
SHD2_k127_6418676_2 PFAM aminotransferase class V K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000004281 239.0
SHD2_k127_6418676_3 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000000000000000000000000000000638 206.0
SHD2_k127_6418676_4 PFAM Diacylglycerol kinase, catalytic - - - 0.0000000000000000000000000000000000000000002703 175.0
SHD2_k127_6418676_5 PFAM Diacylglycerol kinase, catalytic - - - 0.0000000000000000000000000000000000000001259 163.0
SHD2_k127_6418676_6 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000004594 117.0
SHD2_k127_6418676_7 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000004153 111.0
SHD2_k127_6418676_8 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000008621 116.0
SHD2_k127_6418676_9 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000001231 80.0
SHD2_k127_6421937_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 4.748e-212 665.0
SHD2_k127_6421937_1 oligoendopeptidase F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 501.0
SHD2_k127_6421937_10 Rhodanese Homology Domain K03972 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.0001568 48.0
SHD2_k127_6421937_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 354.0
SHD2_k127_6421937_3 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 297.0
SHD2_k127_6421937_5 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 - 1.3.5.2,1.3.98.1 0.00000000000000000000000000000000000006599 146.0
SHD2_k127_6421937_6 - - - - 0.0000000000000000000000000000000216 133.0
SHD2_k127_6421937_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000004484 123.0
SHD2_k127_6421937_8 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000006377 122.0
SHD2_k127_6421937_9 SNARE associated Golgi protein - - - 0.0001086 45.0
SHD2_k127_6436087_0 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 418.0
SHD2_k127_6436087_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 284.0
SHD2_k127_6436087_2 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) - - - 0.000000000000000000000000000000000000000000000000000000004742 209.0
SHD2_k127_6436087_3 helicase activity K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000007588 157.0
SHD2_k127_6436087_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000003497 139.0
SHD2_k127_6450865_0 PFAM IstB domain protein ATP-binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 561.0
SHD2_k127_6450865_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 464.0
SHD2_k127_6450865_2 FAD linked oxidase domain protein K00103,K16653 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.3.8,1.1.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 458.0
SHD2_k127_6450865_3 PFAM diacylglycerol kinase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 313.0
SHD2_k127_6450865_4 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000002571 233.0
SHD2_k127_6450865_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000001741 209.0
SHD2_k127_6450865_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000005956 192.0
SHD2_k127_6450865_7 Helicase conserved C-terminal domain - - - 0.0000000000000000000000000000000000000001573 159.0
SHD2_k127_6450865_8 diguanylate cyclase - - - 0.0000000000000000000000000000000000000411 158.0
SHD2_k127_6450865_9 TIGRFAM primosome, DnaD subunit - - - 0.00000000000002204 75.0
SHD2_k127_645097_0 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 399.0
SHD2_k127_645097_1 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000001676 230.0
SHD2_k127_645097_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000002528 64.0
SHD2_k127_6464710_0 Endoribonuclease that initiates mRNA decay K18682 - - 4.174e-215 678.0
SHD2_k127_6464710_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000001034 203.0
SHD2_k127_6464710_2 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000000003359 183.0
SHD2_k127_6464710_3 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000001779 149.0
SHD2_k127_6485509_0 PFAM peptidase S58, DmpA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 369.0
SHD2_k127_6485509_2 glucan 1,4-alpha-glucosidase activity - - - 0.0006455 53.0
SHD2_k127_6496184_0 SMART Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 505.0
SHD2_k127_6509227_0 ABC transporter, transmembrane region K06147 - - 5.687e-283 882.0
SHD2_k127_6509227_1 Serine threonine protein kinase K12132 - 2.7.11.1 9.749e-276 860.0
SHD2_k127_6509227_10 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000001932 185.0
SHD2_k127_6509227_11 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000000000004596 175.0
SHD2_k127_6509227_12 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000001667 176.0
SHD2_k127_6509227_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000001347 143.0
SHD2_k127_6509227_14 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000004955 140.0
SHD2_k127_6509227_15 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000001428 136.0
SHD2_k127_6509227_16 - - - - 0.0000000000000000000001589 99.0
SHD2_k127_6509227_17 DNA-binding transcription factor activity - - - 0.000000000000000002031 91.0
SHD2_k127_6509227_18 TIR domain - - - 0.0000000000000007196 90.0
SHD2_k127_6509227_2 ABC transporter K06147 - - 4.454e-263 829.0
SHD2_k127_6509227_3 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 398.0
SHD2_k127_6509227_4 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 408.0
SHD2_k127_6509227_5 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 345.0
SHD2_k127_6509227_6 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 308.0
SHD2_k127_6509227_7 DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004135 256.0
SHD2_k127_6509227_8 TIGR00266 family - - - 0.0000000000000000000000000000000000000000000000000000000000000003893 226.0
SHD2_k127_6509227_9 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000008918 188.0
SHD2_k127_6512692_0 PFAM Glycosyl transferase, group 1 - - - 7.037e-296 927.0
SHD2_k127_6512692_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 471.0
SHD2_k127_6512692_2 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 436.0
SHD2_k127_6512692_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 295.0
SHD2_k127_6512692_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000003016 211.0
SHD2_k127_6512692_5 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000009002 224.0
SHD2_k127_6512692_6 - - - - 0.00000000000000000000000000000000000000000000000004709 187.0
SHD2_k127_6512692_7 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10440,K10441 - 3.6.3.17 0.00000000000000000000000000000000000000751 152.0
SHD2_k127_6512692_8 - - - - 0.00000000000000000000000000000000000000971 153.0
SHD2_k127_6512692_9 acid phosphatase activity - - - 0.00000000000000003459 85.0
SHD2_k127_6515954_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000002655 229.0
SHD2_k127_6515954_1 Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000006079 130.0
SHD2_k127_6515954_2 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000000000000637 124.0
SHD2_k127_6515954_3 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000006735 97.0
SHD2_k127_6517639_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 571.0
SHD2_k127_6517639_1 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000007166 241.0
SHD2_k127_6517639_2 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.0000000000000000000000000000000000000000008985 161.0
SHD2_k127_6517639_3 response to abiotic stimulus - - - 0.0000000000000000000006401 101.0
SHD2_k127_6517639_4 - - - - 0.00000006037 64.0
SHD2_k127_6517639_5 PFAM Glycosyl transferase family 2 K14597 - - 0.000003812 51.0
SHD2_k127_6531451_0 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 445.0
SHD2_k127_6531451_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000576 228.0
SHD2_k127_6531451_2 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000005465 224.0
SHD2_k127_6531451_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000003294 184.0
SHD2_k127_6531451_4 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000006322 113.0
SHD2_k127_6531451_5 PFAM response regulator receiver K07664 - - 0.0000000000000004267 82.0
SHD2_k127_6531451_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464 - 3.5.2.2 0.000000000000001328 78.0
SHD2_k127_6535346_0 Aconitase family (aconitate hydratase) - - - 6.66e-299 928.0
SHD2_k127_6535346_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 454.0
SHD2_k127_6535346_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658,K09699 - 2.3.1.12,2.3.1.168,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006596 429.0
SHD2_k127_6545574_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 549.0
SHD2_k127_6545574_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 393.0
SHD2_k127_6545574_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000207 271.0
SHD2_k127_6545574_3 - K09700 - - 0.00000000000000000000000000000000000002048 146.0
SHD2_k127_6545574_4 - - - - 0.00000000000000000005897 99.0
SHD2_k127_6545574_5 Maltose permease K05820,K07112 - - 0.0000000000000000003664 101.0
SHD2_k127_6545574_6 PFAM Amylo-alpha-16-glucosidase - - - 0.000000001261 70.0
SHD2_k127_6550218_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 475.0
SHD2_k127_6550218_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000000000000007502 218.0
SHD2_k127_6550218_2 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851,K13007 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000002591 160.0
SHD2_k127_6555936_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 619.0
SHD2_k127_6555936_1 CpXC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 372.0
SHD2_k127_6555936_2 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 300.0
SHD2_k127_6555936_3 PLD-like domain K03205 - - 0.000000000000004593 76.0
SHD2_k127_6566706_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000007552 177.0
SHD2_k127_6566706_1 GDP-mannose mannosyl hydrolase activity K01515,K03574,K13669,K19710 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.53,3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000000000001289 170.0
SHD2_k127_6566706_2 - - - - 0.000000000000000000000003747 113.0
SHD2_k127_6566706_3 PFAM Methyltransferase type K15256 - - 0.000002986 50.0
SHD2_k127_6568112_0 histidine kinase A domain protein - - - 0.0 1234.0
SHD2_k127_6568112_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002129 282.0
SHD2_k127_6568112_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000002771 176.0
SHD2_k127_6568112_3 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.00000000002669 65.0
SHD2_k127_6570346_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005448 274.0
SHD2_k127_6570346_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000003732 226.0
SHD2_k127_6570346_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000006376 195.0
SHD2_k127_6570346_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000004469 139.0
SHD2_k127_6570346_4 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.0000000000000000000000000001574 119.0
SHD2_k127_6570346_5 YwiC-like protein - - - 0.00000000001356 74.0
SHD2_k127_6570346_6 Cytochrome C oxidase, cbb3-type, subunit III K19713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016669,GO:0050338,GO:0055114 1.8.2.2 0.00002432 55.0
SHD2_k127_6570346_7 Glycosyltransferase like family 2 - - - 0.0001668 44.0
SHD2_k127_6580066_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 7.323e-269 837.0
SHD2_k127_6580066_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.589e-248 773.0
SHD2_k127_6580066_10 subunit (C K02119 - - 0.0000000000000000000000000000000000000002043 163.0
SHD2_k127_6580066_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000001067 153.0
SHD2_k127_6580066_12 ATP synthase subunit C K02124 - - 0.000000000000000000006158 98.0
SHD2_k127_6580066_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000006266 93.0
SHD2_k127_6580066_14 -ATPase subunit F K02122 - - 0.000000000000008969 81.0
SHD2_k127_6580066_15 transferase activity, transferring alkyl or aryl (other than methyl) groups - - - 0.000003229 59.0
SHD2_k127_6580066_16 H subunit K02107 - - 0.0000478 49.0
SHD2_k127_6580066_17 Vacuolar ATP synthase subunit E K02150 GO:0000221,GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006885,GO:0007035,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015988,GO:0015991,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016471,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019725,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030641,GO:0031090,GO:0031224,GO:0032991,GO:0033176,GO:0033178,GO:0033180,GO:0034220,GO:0036442,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044422,GO:0044424,GO:0044425,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044769,GO:0045851,GO:0046961,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0090662,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098796,GO:0098805,GO:0098852,GO:0099131,GO:0099132,GO:1902600 - 0.0004045 50.0
SHD2_k127_6580066_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.054e-234 739.0
SHD2_k127_6580066_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 601.0
SHD2_k127_6580066_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 469.0
SHD2_k127_6580066_5 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 373.0
SHD2_k127_6580066_6 ATP hydrolysis coupled proton transport K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 340.0
SHD2_k127_6580066_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 308.0
SHD2_k127_6580066_8 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000007471 222.0
SHD2_k127_6580066_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000004697 170.0
SHD2_k127_6591267_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 371.0
SHD2_k127_6591267_1 PFAM Shikimate quinate 5-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 359.0
SHD2_k127_6591267_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 334.0
SHD2_k127_6591267_3 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.0000000000000000000000000000000000000000000000000000006962 204.0
SHD2_k127_6591267_4 Cache domain - - - 0.000000000000000000000000000000000000007116 168.0
SHD2_k127_6591267_5 Sporulation and spore germination - - - 0.000000000000005311 89.0
SHD2_k127_6591267_6 peptidase - - - 0.000000000001376 81.0
SHD2_k127_6591267_7 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00001519 55.0
SHD2_k127_6604001_0 thiolester hydrolase activity K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000001089 160.0
SHD2_k127_6604001_1 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.00000000000000000000000000000001987 135.0
SHD2_k127_6604001_2 Protein of unknown function (DUF1572) - - - 0.00000000000000000006941 95.0
SHD2_k127_6608782_0 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' K00231,K00514,K02293,K09879,K21677 - 1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 424.0
SHD2_k127_6608782_1 Putative glutamine amidotransferase K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001455 286.0
SHD2_k127_6608782_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000204 72.0
SHD2_k127_6615540_0 Histidine kinase K07680,K07778,K11617,K14988 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 399.0
SHD2_k127_6615540_1 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 349.0
SHD2_k127_6615540_11 Domain of unknown function (DUF4118) - - - 0.00000000000000000000000000000000000121 156.0
SHD2_k127_6615540_12 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000000000000428 133.0
SHD2_k127_6615540_13 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000001734 118.0
SHD2_k127_6615540_14 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000000000000000000000286 116.0
SHD2_k127_6615540_16 PFAM NAD dependent epimerase dehydratase family - - - 0.0000000000000007036 79.0
SHD2_k127_6615540_17 - - - - 0.0000003013 60.0
SHD2_k127_6615540_2 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 327.0
SHD2_k127_6615540_3 PFAM DJ-1 PfpI family K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001301 283.0
SHD2_k127_6615540_4 response regulator K02479,K07695 GO:0001666,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009405,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0018995,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030312,GO:0030430,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032502,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0036293,GO:0043656,GO:0043657,GO:0044174,GO:0044215,GO:0044216,GO:0044217,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070482,GO:0071944,GO:0072493,GO:0080090,GO:0080134,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1902882,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004682 280.0
SHD2_k127_6615540_5 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001116 276.0
SHD2_k127_6615540_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003988 275.0
SHD2_k127_6615540_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001844 262.0
SHD2_k127_6615540_8 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01501,K12251 - 3.5.1.53,3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000001624 247.0
SHD2_k127_6615540_9 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004908 237.0
SHD2_k127_6616636_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 593.0
SHD2_k127_6616636_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 443.0
SHD2_k127_6616636_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000006834 265.0
SHD2_k127_6616636_3 methyltransferase activity - - - 0.000000000000000000000000000000000000167 147.0
SHD2_k127_6616636_4 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000001252 126.0
SHD2_k127_6616636_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000005235 84.0
SHD2_k127_6616636_6 Protein of unknown function (DUF2905) - - - 0.000000000000001316 78.0
SHD2_k127_6616636_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000007562 48.0
SHD2_k127_6629301_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 482.0
SHD2_k127_6629301_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 414.0
SHD2_k127_6629301_2 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000137 194.0
SHD2_k127_6629301_3 Divergent PAP2 family K09775 - - 0.0000000000000000000000000000000000000000000000006521 179.0
SHD2_k127_6629301_4 PLD-like domain - - - 0.00000000000000000000000000003529 127.0
SHD2_k127_6629301_5 Cna B domain protein - - - 0.0000000000001008 81.0
SHD2_k127_6629301_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00001818 50.0
SHD2_k127_6639286_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 9.921e-197 655.0
SHD2_k127_6639286_1 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001957 279.0
SHD2_k127_6639286_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000005744 185.0
SHD2_k127_6644891_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 374.0
SHD2_k127_6644891_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000009763 172.0
SHD2_k127_6644891_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000008779 161.0
SHD2_k127_6644891_3 cellular response to heat K09807 - - 0.00000000000000000000003807 105.0
SHD2_k127_6651677_0 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 370.0
SHD2_k127_6651677_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 357.0
SHD2_k127_6651677_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.000000000000000000000000001559 113.0
SHD2_k127_6651677_3 - - - - 0.00000000000000003644 83.0
SHD2_k127_6651677_4 Domain of unknown function DUF11 - - - 0.0000000000216 67.0
SHD2_k127_6670858_0 ABC transporter transmembrane region K06147 - - 1.551e-215 683.0
SHD2_k127_6670858_1 - - - - 0.0000000000007521 78.0
SHD2_k127_6683161_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 344.0
SHD2_k127_6683161_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 340.0
SHD2_k127_6683161_2 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 348.0
SHD2_k127_6683161_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 300.0
SHD2_k127_6683161_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000005647 234.0
SHD2_k127_6683161_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000006151 196.0
SHD2_k127_6683161_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000003135 181.0
SHD2_k127_6683161_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000002306 99.0
SHD2_k127_6683161_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000001499 61.0
SHD2_k127_6695704_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008848 303.0
SHD2_k127_6695704_1 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008295 280.0
SHD2_k127_6695704_2 Protein of unknown function (DUF952) K00799,K01560,K21420 - 2.3.2.29,2.5.1.18,3.8.1.2 0.00000000000000000000000002606 112.0
SHD2_k127_6702878_0 SMART Adenylyl cyclase class-3 4 guanylyl cyclase - - - 4.189e-272 887.0
SHD2_k127_6702878_1 homoserine transmembrane transporter activity K06600,K06895 - - 0.0000000000000000000000000000000000000000000000000000000000000001611 228.0
SHD2_k127_6702878_2 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000000000000000000000000000000000000004465 203.0
SHD2_k127_6702878_3 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000554 137.0
SHD2_k127_6702878_4 Psort location CytoplasmicMembrane, score - - - 0.000000004924 65.0
SHD2_k127_6712421_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000108 200.0
SHD2_k127_6712421_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000003996 166.0
SHD2_k127_6712421_3 Methyltransferase - - - 0.000000000000000007645 93.0
SHD2_k127_6718761_0 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.0000000000000000000000000000000000000000003292 163.0
SHD2_k127_6718761_1 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000000000006925 150.0
SHD2_k127_6756736_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000002721 215.0
SHD2_k127_6757779_0 Aminotransferase K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 608.0
SHD2_k127_6757779_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 336.0
SHD2_k127_6757779_2 Cytochrome c, class I - - - 0.0000000000000001181 85.0
SHD2_k127_6757779_3 Rubrerythrin - - - 0.0009234 48.0
SHD2_k127_6765050_0 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 543.0
SHD2_k127_6765050_1 Nacht domain K13730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 426.0
SHD2_k127_6765050_2 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 297.0
SHD2_k127_6765050_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008034 282.0
SHD2_k127_6765050_4 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000003465 215.0
SHD2_k127_6765050_5 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000000000000000000000000000000000000000001283 185.0
SHD2_k127_6794304_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 500.0
SHD2_k127_6794304_1 DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 397.0
SHD2_k127_6794304_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 377.0
SHD2_k127_6794304_3 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000003537 177.0
SHD2_k127_6794304_4 Virulence activator alpha C-term - - - 0.000000000000000000000000000000003533 134.0
SHD2_k127_6794304_5 Transglycosylase associated protein - - - 0.00000000000000000000003289 102.0
SHD2_k127_6798963_0 response to pH - - - 0.0000000000000000000000000000000000000000000000000000001054 200.0
SHD2_k127_6798963_1 deoxyhypusine monooxygenase activity K03301 - - 0.000000000000000000000000000000000000000002981 179.0
SHD2_k127_6798963_2 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000002209 156.0
SHD2_k127_6803315_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 302.0
SHD2_k127_6803315_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 304.0
SHD2_k127_6803315_2 Redoxin K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 289.0
SHD2_k127_6803315_3 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 306.0
SHD2_k127_6803315_4 amino acid-binding ACT domain protein K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000848 258.0
SHD2_k127_6825305_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 352.0
SHD2_k127_6825305_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000008301 248.0
SHD2_k127_6825305_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000003634 137.0
SHD2_k127_6825305_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000008651 125.0
SHD2_k127_682849_0 Belongs to the SEDS family - - - 1.609e-214 691.0
SHD2_k127_682849_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 417.0
SHD2_k127_682849_10 - - - - 0.00000000006023 67.0
SHD2_k127_682849_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 294.0
SHD2_k127_682849_3 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004218 271.0
SHD2_k127_682849_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000308 191.0
SHD2_k127_682849_5 sh3 domain protein K01448 - 3.5.1.28 0.000000000000000000000000000000000001145 147.0
SHD2_k127_682849_6 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000009103 117.0
SHD2_k127_682849_7 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000006511 105.0
SHD2_k127_682849_8 PFAM Forkhead-associated protein - - - 0.00000000000000000000002281 110.0
SHD2_k127_682849_9 sh3 domain protein K01448 - 3.5.1.28 0.00000000000000000000007766 107.0
SHD2_k127_6830540_0 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 289.0
SHD2_k127_6830540_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000008945 164.0
SHD2_k127_6886657_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 1.587e-246 774.0
SHD2_k127_6886657_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 595.0
SHD2_k127_6886657_2 histidine kinase A domain protein K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001612 284.0
SHD2_k127_6886657_3 response regulator K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003521 250.0
SHD2_k127_6886657_4 amino acid - - - 0.000000000000000001477 100.0
SHD2_k127_6896120_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006773 248.0
SHD2_k127_6896120_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000002651 231.0
SHD2_k127_6896120_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000422 238.0
SHD2_k127_6896120_3 - - - - 0.000000000000000000000000000000000000000000000006585 183.0
SHD2_k127_6913064_0 Methyltransferase domain - - - 0.00000000000000000000004123 109.0
SHD2_k127_6929225_0 proline dipeptidase activity - - - 2.211e-227 711.0
SHD2_k127_6929225_1 PFAM WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 589.0
SHD2_k127_6929225_2 PFAM Transketolase central region K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 520.0
SHD2_k127_6929225_3 PFAM dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 464.0
SHD2_k127_6929225_4 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 306.0
SHD2_k127_6929225_5 Cupin domain - - - 0.00000000000000000000000000000000002836 143.0
SHD2_k127_6929225_6 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000002833 116.0
SHD2_k127_6929225_7 Putative stress-induced transcription regulator - - - 0.0000000000008017 68.0
SHD2_k127_6949086_0 radical SAM domain protein - - - 5.772e-198 626.0
SHD2_k127_6949086_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 582.0
SHD2_k127_6949086_10 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000003096 204.0
SHD2_k127_6949086_11 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.000000000000000000000000000000000000000000000000000001347 199.0
SHD2_k127_6949086_12 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000002252 139.0
SHD2_k127_6949086_13 - - - - 0.00000000000000000000003702 113.0
SHD2_k127_6949086_2 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 455.0
SHD2_k127_6949086_3 GH3 auxin-responsive promoter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 439.0
SHD2_k127_6949086_4 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 342.0
SHD2_k127_6949086_5 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003876 263.0
SHD2_k127_6949086_6 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008787 263.0
SHD2_k127_6949086_7 PFAM methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000004215 247.0
SHD2_k127_6949086_8 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000003788 245.0
SHD2_k127_6949086_9 - - - - 0.000000000000000000000000000000000000000000000000000000000002914 216.0
SHD2_k127_6950888_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 493.0
SHD2_k127_6950888_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 287.0
SHD2_k127_6950888_2 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000005999 247.0
SHD2_k127_6950888_3 transcriptional regulator domain protein - - - 0.00000000000000000000000000000000001983 143.0
SHD2_k127_6950888_4 YbaB/EbfC DNA-binding family K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000007967 136.0
SHD2_k127_6950888_5 - - - - 0.00000006309 59.0
SHD2_k127_6950888_6 - - - - 0.000006244 57.0
SHD2_k127_696878_0 - K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 489.0
SHD2_k127_696878_1 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001534 271.0
SHD2_k127_6969017_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 332.0
SHD2_k127_6969017_1 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 319.0
SHD2_k127_6969017_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000001371 155.0
SHD2_k127_6969017_3 nuclease - - - 0.000000000000272 78.0
SHD2_k127_6969017_4 - - - - 0.0000000000005976 77.0
SHD2_k127_7011734_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 395.0
SHD2_k127_7011734_1 LysM domain - - - 0.00000000000000000000000000000000000000000000001927 181.0
SHD2_k127_7011734_2 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000001706 142.0
SHD2_k127_7011734_3 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000000001592 126.0
SHD2_k127_7011734_4 Peptidase family M50 K11749 - - 0.000128 53.0
SHD2_k127_7015203_0 Belongs to the carbamoyltransferase HypF family K04656 - - 8.691e-218 702.0
SHD2_k127_7015203_1 Formate/nitrite transporter K06212 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 371.0
SHD2_k127_7015203_2 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 350.0
SHD2_k127_7015203_3 Hydrogenase accessory protein HypB K03189,K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 312.0
SHD2_k127_7015203_4 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000001986 181.0
SHD2_k127_7015203_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000009785 116.0
SHD2_k127_7015203_6 Hydrogenase expression formation protein K04653 - - 0.000000000000000000000002314 104.0
SHD2_k127_7015203_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000002755 76.0
SHD2_k127_7018017_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 532.0
SHD2_k127_7018017_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 364.0
SHD2_k127_7018017_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000024 196.0
SHD2_k127_7018017_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000001451 159.0
SHD2_k127_7034560_0 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 331.0
SHD2_k127_7034560_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000002967 125.0
SHD2_k127_7034560_2 - - - - 0.0000000000000000000000006071 108.0
SHD2_k127_7034560_3 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000001204 115.0
SHD2_k127_7034560_4 SPFH domain Band 7 family - - - 0.000000003965 63.0
SHD2_k127_7039573_0 PFAM Amidohydrolase 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 584.0
SHD2_k127_7039573_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 353.0
SHD2_k127_7039573_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000004997 61.0
SHD2_k127_7039573_2 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 326.0
SHD2_k127_7039573_3 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001875 274.0
SHD2_k127_7039573_4 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
SHD2_k127_7039573_5 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.000000000000000000000000000000000000000000000000000000000002023 219.0
SHD2_k127_7039573_6 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000005912 185.0
SHD2_k127_7039573_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000000000000000003504 158.0
SHD2_k127_7039573_8 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000006651 96.0
SHD2_k127_7039573_9 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002655 86.0
SHD2_k127_7048365_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 368.0
SHD2_k127_7048365_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002369 257.0
SHD2_k127_7048365_2 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000000000000002914 213.0
SHD2_k127_7048365_3 Domain of unknown function (DUF333) K14475 - - 0.00000000000005382 78.0
SHD2_k127_7048365_4 Zinc-binding dehydrogenase - - - 0.00000000000636 66.0
SHD2_k127_7053976_0 PFAM Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 291.0
SHD2_k127_7053976_1 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 291.0
SHD2_k127_7053976_2 PFAM ABC transporter related K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000002585 199.0
SHD2_k127_7066838_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 581.0
SHD2_k127_710217_0 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 369.0
SHD2_k127_710217_1 Cupin domain - - - 0.0000000000000000000000000000003062 124.0
SHD2_k127_710217_2 TIR domain - - - 0.000000000000000475 90.0
SHD2_k127_7127357_0 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 447.0
SHD2_k127_7127357_1 ATPase activity K10111,K10112,K17240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001579 283.0
SHD2_k127_7127357_10 HEAT repeat - - - 0.0000007656 60.0
SHD2_k127_7127357_2 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009381 250.0
SHD2_k127_7127357_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000003971 168.0
SHD2_k127_7127357_4 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000007998 158.0
SHD2_k127_7127357_5 - - - - 0.000000000000000000000000000000000003279 143.0
SHD2_k127_7127357_6 Phospholipid methyltransferase - - - 0.0000000000000000000000000003004 115.0
SHD2_k127_7127357_7 GDP-mannose mannosyl hydrolase activity K00974,K03574,K18445 - 2.7.7.72,3.6.1.55,3.6.1.61 0.0000000000000000000002499 102.0
SHD2_k127_7127357_8 Short chain dehydrogenase - - - 0.00000000002752 69.0
SHD2_k127_7127357_9 ubiE/COQ5 methyltransferase family - - - 0.0000000001237 66.0
SHD2_k127_7157468_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 578.0
SHD2_k127_7157468_1 helix_turn_helix, Lux Regulon K02479 - - 0.00000000000000000000000000000000000000000845 161.0
SHD2_k127_7157468_2 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000143 155.0
SHD2_k127_7157468_3 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000001998 139.0
SHD2_k127_7157468_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000839 48.0
SHD2_k127_716010_0 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002513 281.0
SHD2_k127_716010_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004941 295.0
SHD2_k127_716010_2 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000000000000002384 100.0
SHD2_k127_7161_0 oxidoreductase activity K02012,K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 434.0
SHD2_k127_7161_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 393.0
SHD2_k127_7161_10 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000006479 175.0
SHD2_k127_7161_11 DinB family - - - 0.000000000000000000000000000000000000000000006226 168.0
SHD2_k127_7161_12 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000004243 160.0
SHD2_k127_7161_13 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000002288 164.0
SHD2_k127_7161_15 Sulfatase-modifying factor enzyme 1 K20333 - - 0.000000000000000000000000000000003332 138.0
SHD2_k127_7161_16 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000001217 101.0
SHD2_k127_7161_18 Represses a number of genes involved in the response to DNA damage (SOS response) - - - 0.000000002222 69.0
SHD2_k127_7161_19 4Fe-4S dicluster domain - - - 0.000000003527 61.0
SHD2_k127_7161_2 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 376.0
SHD2_k127_7161_20 PFAM DUF218 domain - - - 0.0002141 51.0
SHD2_k127_7161_3 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009921 352.0
SHD2_k127_7161_4 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 336.0
SHD2_k127_7161_5 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001026 284.0
SHD2_k127_7161_6 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001178 242.0
SHD2_k127_7161_7 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000001475 222.0
SHD2_k127_7161_8 PHP-associated - - - 0.0000000000000000000000000000000000000000000000003416 184.0
SHD2_k127_7161_9 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000003066 179.0
SHD2_k127_721637_0 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 448.0
SHD2_k127_721637_1 Bacterial cellulose synthase subunit K20541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 348.0
SHD2_k127_721637_2 Helix-turn-helix domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001832 266.0
SHD2_k127_721637_3 lipopolysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001056 239.0
SHD2_k127_721637_4 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001046 209.0
SHD2_k127_721637_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000001492 129.0
SHD2_k127_729025_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.753e-226 707.0
SHD2_k127_729025_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 454.0
SHD2_k127_729025_2 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 355.0
SHD2_k127_729025_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000004439 156.0
SHD2_k127_729025_4 - - - - 0.000001477 56.0
SHD2_k127_729025_5 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00002533 48.0
SHD2_k127_7299817_0 PFAM CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 319.0
SHD2_k127_7299817_1 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000001576 123.0
SHD2_k127_7299817_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000228 97.0
SHD2_k127_7299817_3 - - - - 0.00000000000000007795 81.0
SHD2_k127_7299817_4 Protease prsW family - - - 0.000000000002899 78.0
SHD2_k127_7299817_5 Psort location CytoplasmicMembrane, score K03406,K07315,K07675,K16924,K17763 - 2.7.13.3,3.1.3.3 0.00001071 56.0
SHD2_k127_7348353_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 371.0
SHD2_k127_7348353_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000009739 111.0
SHD2_k127_7389279_0 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 447.0
SHD2_k127_7389279_1 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 411.0
SHD2_k127_7389279_10 glyoxalase III activity - - - 0.000000000000000703 83.0
SHD2_k127_7389279_11 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) K11294 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000002609 80.0
SHD2_k127_7389279_12 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000114 70.0
SHD2_k127_7389279_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 380.0
SHD2_k127_7389279_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 358.0
SHD2_k127_7389279_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 334.0
SHD2_k127_7389279_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006491 262.0
SHD2_k127_7389279_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005093 257.0
SHD2_k127_7389279_7 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000003486 217.0
SHD2_k127_7389279_8 response regulator K07686,K07689,K20264 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000006085 122.0
SHD2_k127_7389279_9 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000391 105.0
SHD2_k127_7407466_0 Belongs to the RtcB family K14415 - 6.5.1.3 2.005e-237 743.0
SHD2_k127_7407466_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 531.0
SHD2_k127_7407466_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 404.0
SHD2_k127_7407466_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 345.0
SHD2_k127_7407466_4 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 0.0000000000000000000000000000000000006044 141.0
SHD2_k127_7407466_5 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000375 136.0
SHD2_k127_7407466_6 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000472 111.0
SHD2_k127_7407466_7 PFAM TadE family protein - - - 0.00000000000001704 86.0
SHD2_k127_7419867_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000007189 216.0
SHD2_k127_7419867_1 2 iron, 2 sulfur cluster binding K02823,K05368 - 1.16.1.3,1.5.1.41 0.000000000000000000000000000000000003421 146.0
SHD2_k127_7419867_2 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000009509 141.0
SHD2_k127_7419867_3 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000007417 143.0
SHD2_k127_7426840_0 Type I site-specific restriction-modification system, R (Restriction) subunit and related - - - 4.224e-289 910.0
SHD2_k127_7426840_1 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000139 208.0
SHD2_k127_7426840_2 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000003373 138.0
SHD2_k127_7426840_3 GUN4-like - - - 0.0000000000000000000000000002527 125.0
SHD2_k127_7426840_4 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.000000000000000000000000001524 116.0
SHD2_k127_7426840_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000007817 100.0
SHD2_k127_7426840_6 - - - - 0.000000000006677 68.0
SHD2_k127_7426840_7 Protein of unknown function (DUF1648) - - - 0.00000004137 61.0
SHD2_k127_7426840_8 PFAM N-6 DNA methylase K03427 - 2.1.1.72 0.0001764 46.0
SHD2_k127_7428356_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 599.0
SHD2_k127_7428356_1 PFAM Penicillin binding protein transpeptidase domain K17838 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000006469 258.0
SHD2_k127_7428356_2 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000002218 187.0
SHD2_k127_7428356_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000006399 131.0
SHD2_k127_7439490_0 short-chain dehydrogenase reductase SDR K12454 - 5.1.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 443.0
SHD2_k127_7439490_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006439 266.0
SHD2_k127_7439490_2 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004274 235.0
SHD2_k127_7439490_3 lysyltransferase activity K07027 - - 0.000000000000000000002628 103.0
SHD2_k127_7456668_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 589.0
SHD2_k127_7456668_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 564.0
SHD2_k127_7456668_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 320.0
SHD2_k127_7456668_3 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000001288 221.0
SHD2_k127_7456668_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000003676 126.0
SHD2_k127_7456668_5 single-species biofilm formation K01790,K03806,K06175 GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 3.5.1.28,5.1.3.13,5.4.99.26 0.0000000000000000000000001251 109.0
SHD2_k127_7456668_6 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.0000000000000008133 88.0
SHD2_k127_748205_0 PFAM glycosidase PH1107-related K18785,K20885 - 2.4.1.319,2.4.1.320,2.4.1.339,2.4.1.340 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 543.0
SHD2_k127_748205_1 Family 4 glycosyl hydrolase K01222 - 3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 521.0
SHD2_k127_748205_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 301.0
SHD2_k127_748205_3 Glyco_18 K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000006526 243.0
SHD2_k127_748205_4 PFAM extracellular solute-binding protein family 1 K02027 - - 0.00000000000000000000000000000000000000000001238 177.0
SHD2_k127_748205_5 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000235 137.0
SHD2_k127_7492588_0 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000158 205.0
SHD2_k127_7492588_1 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - 0.000000000000000000000000000000000000000002607 162.0
SHD2_k127_7492588_2 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000188 147.0
SHD2_k127_7492588_3 thiolester hydrolase activity K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000001036 118.0
SHD2_k127_7492588_4 - - - - 0.0000000000000000002435 100.0
SHD2_k127_7492588_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000181 81.0
SHD2_k127_749626_0 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 563.0
SHD2_k127_749626_1 Glycosyl transferase family 4 K02851,K13007 - 2.7.8.33,2.7.8.35 0.00000000000000000000009624 105.0
SHD2_k127_7513749_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 316.0
SHD2_k127_7513749_1 Nacht domain K06147 - - 0.0000000000000000000000000000000000003478 150.0
SHD2_k127_7513749_2 Protein of unknown function (DUF2568) - - - 0.00000000000000000000002042 104.0
SHD2_k127_7513749_3 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000004982 93.0
SHD2_k127_7513749_4 PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml - - - 0.00000000004565 68.0
SHD2_k127_7513749_5 Endoribonuclease L-PSP - - - 0.0000003388 51.0
SHD2_k127_7561162_0 Creatinine amidohydrolase - - - 0.00000000000000000000000001793 122.0
SHD2_k127_7561162_1 ornithine carbamoyltransferase K00611 - 2.1.3.3 0.0000000000009902 70.0
SHD2_k127_7561162_2 Acetyltransferase (GNAT) domain K03824 - - 0.00000008056 55.0
SHD2_k127_7562512_0 PFAM ABC transporter related K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 463.0
SHD2_k127_7562512_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 422.0
SHD2_k127_7562512_2 PFAM basic membrane lipoprotein K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 331.0
SHD2_k127_7562512_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001345 267.0
SHD2_k127_7562512_4 PFAM ABC transporter related K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000002009 217.0
SHD2_k127_7572319_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 432.0
SHD2_k127_7572319_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001 272.0
SHD2_k127_7572319_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000145 257.0
SHD2_k127_7572319_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000001057 246.0
SHD2_k127_7572319_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000001203 124.0
SHD2_k127_7572319_5 Alcohol dehydrogenase GroES-like domain - - - 0.000000000006631 68.0
SHD2_k127_7572319_6 - - - - 0.00000000002205 76.0
SHD2_k127_7580711_0 Natural resistance-associated macrophage protein K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 574.0
SHD2_k127_7580711_1 PFAM aminotransferase class V K01634 - 4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 407.0
SHD2_k127_7580711_2 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 310.0
SHD2_k127_7580711_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000005465 203.0
SHD2_k127_7580711_4 D-ala D-ala ligase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000001234 206.0
SHD2_k127_7580711_5 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000001898 110.0
SHD2_k127_7620232_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1217.0
SHD2_k127_7620232_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 6.458e-316 983.0
SHD2_k127_7620232_10 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000000000004757 167.0
SHD2_k127_7620232_11 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000004673 130.0
SHD2_k127_7620232_12 ABC-2 family transporter protein K01992 - - 0.00000000000000005854 94.0
SHD2_k127_7620232_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 518.0
SHD2_k127_7620232_3 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 467.0
SHD2_k127_7620232_4 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 354.0
SHD2_k127_7620232_5 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 340.0
SHD2_k127_7620232_6 ligase activity K01469 - 3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 295.0
SHD2_k127_7620232_7 Methionine synthase B12-binding module cap domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009997 251.0
SHD2_k127_7620232_8 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000002796 244.0
SHD2_k127_7620232_9 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000004096 231.0
SHD2_k127_76260_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 323.0
SHD2_k127_76260_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 321.0
SHD2_k127_76260_2 Uncharacterized protein family UPF0029 K00560,K01271 - 2.1.1.45,3.4.13.9 0.00000000000000000000000000000000000000000000000000005785 194.0
SHD2_k127_76260_3 - - - - 0.0000000000000000000000000000000002789 147.0
SHD2_k127_76260_4 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000001248 69.0
SHD2_k127_76260_5 - - - - 0.0002964 44.0
SHD2_k127_765202_0 phosphorelay sensor kinase activity K01768,K02482,K02584,K07673,K10819 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 391.0
SHD2_k127_765202_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 337.0
SHD2_k127_765202_10 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000009767 260.0
SHD2_k127_765202_11 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000002832 237.0
SHD2_k127_765202_12 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000002165 224.0
SHD2_k127_765202_13 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000004044 226.0
SHD2_k127_765202_14 cheY-homologous receiver domain K11443 - - 0.0000000000000000000000000000000000000000001896 162.0
SHD2_k127_765202_15 Histidine kinase K01768,K03406,K11617 - 2.7.13.3,4.6.1.1 0.000000000000000005848 99.0
SHD2_k127_765202_17 diguanylate cyclase K19168 - - 0.0002987 53.0
SHD2_k127_765202_2 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 338.0
SHD2_k127_765202_3 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 307.0
SHD2_k127_765202_4 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 301.0
SHD2_k127_765202_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003282 267.0
SHD2_k127_765202_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001327 268.0
SHD2_k127_765202_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000247 251.0
SHD2_k127_765202_8 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003379 239.0
SHD2_k127_765202_9 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001913 256.0
SHD2_k127_7663467_0 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009557 385.0
SHD2_k127_7663467_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 344.0
SHD2_k127_7663467_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 301.0
SHD2_k127_7663467_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006346 277.0
SHD2_k127_7663467_4 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004603 259.0
SHD2_k127_7663467_5 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000001191 142.0
SHD2_k127_7663467_6 Transcriptional regulator - - - 0.000000000000000000000000007841 119.0
SHD2_k127_7663467_7 PR domain containing 9 K20796 - 2.1.1.43 0.000006327 51.0
SHD2_k127_7699218_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 378.0
SHD2_k127_7699218_1 transmembrane transport K01992,K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001188 277.0
SHD2_k127_7699218_10 - - - - 0.000000000001588 73.0
SHD2_k127_7699218_11 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.0000000006523 62.0
SHD2_k127_7699218_12 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000002022 59.0
SHD2_k127_7699218_2 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002191 259.0
SHD2_k127_7699218_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000003483 237.0
SHD2_k127_7699218_4 PFAM DoxX family protein K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000000000000000007702 216.0
SHD2_k127_7699218_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000007104 169.0
SHD2_k127_7699218_6 PFAM Stage V sporulation protein S K06416 - - 0.00000000000000000000000000000004441 128.0
SHD2_k127_7699218_7 Regulatory protein, FmdB family - - - 0.000000000000000000001536 96.0
SHD2_k127_7699218_8 - - - - 0.00000000000000006049 82.0
SHD2_k127_7699218_9 - - - - 0.0000000000009053 74.0
SHD2_k127_7716587_0 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004636 257.0
SHD2_k127_7716587_1 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001456 252.0
SHD2_k127_7716587_2 Serine Threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000006253 241.0
SHD2_k127_7716587_3 Gaf domain - - - 0.00000000000000000007864 104.0
SHD2_k127_7716587_4 histidine kinase A domain protein - - - 0.000002812 61.0
SHD2_k127_7718737_0 Zn-dependent proteases and their inactivated homologs K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 399.0
SHD2_k127_7718737_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000003454 135.0
SHD2_k127_7719213_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.048e-247 777.0
SHD2_k127_7719213_1 PFAM ABC transporter related K16786,K16787 - - 5.533e-197 627.0
SHD2_k127_7719213_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 355.0
SHD2_k127_7719213_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005665 263.0
SHD2_k127_7719213_4 Methyltransferase small domain K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000008148 200.0
SHD2_k127_7719213_5 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000003141 183.0
SHD2_k127_7719213_6 ECF-type riboflavin transporter, S component K16924 - - 0.00000000000000000002852 96.0
SHD2_k127_7719213_7 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00002569 47.0
SHD2_k127_7745579_0 PFAM amidohydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 538.0
SHD2_k127_7745579_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 436.0
SHD2_k127_7745579_2 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 0.0000000000000000000000000003284 118.0
SHD2_k127_7745579_3 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000002366 102.0
SHD2_k127_7746578_0 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 511.0
SHD2_k127_7746578_1 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 314.0
SHD2_k127_7746578_2 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 291.0
SHD2_k127_7746578_3 PFAM polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000742 205.0
SHD2_k127_7746578_4 - - - - 0.000000000000000000000000000000000000000000001067 179.0
SHD2_k127_7746578_5 -O-antigen - - - 0.000000000000000000000000000003246 136.0
SHD2_k127_7746578_6 YCII-related domain - - - 0.00000000000000000000000007254 110.0
SHD2_k127_7746578_7 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000004298 87.0
SHD2_k127_7746578_9 GGDEF domain - - - 0.0003492 51.0
SHD2_k127_7766456_0 GTPase subunit of restriction endonuclease K07452 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015666,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0017111,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 406.0
SHD2_k127_7766456_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 299.0
SHD2_k127_7766456_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000924 196.0
SHD2_k127_7766456_3 McrBC 5-methylcytosine restriction system component K19147 - - 0.000000000000000000000000000000000000000000000000001275 197.0
SHD2_k127_7766456_4 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000001309 179.0
SHD2_k127_7766456_5 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000009113 166.0
SHD2_k127_779337_0 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 449.0
SHD2_k127_779337_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 400.0
SHD2_k127_779337_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000002411 181.0
SHD2_k127_779337_3 iron-sulfur cluster assembly K02426,K07125 - - 0.0000000000000000000000000000000000000000003112 164.0
SHD2_k127_779337_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000001062 172.0
SHD2_k127_779337_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000001721 138.0
SHD2_k127_779337_7 YCII-related domain - - - 0.00000000000000000000000000000004806 127.0
SHD2_k127_779337_8 RNHCP domain - - - 0.000000000000000001071 93.0
SHD2_k127_779337_9 Helix-turn-helix XRE-family like proteins - - - 0.0002551 49.0
SHD2_k127_7817707_0 Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 307.0
SHD2_k127_7817707_1 Fe-S protein K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004787 252.0
SHD2_k127_7817707_2 Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000000000000000001177 207.0
SHD2_k127_7817707_3 PFAM Nitroreductase - - - 0.00000000000000000000000000000000124 136.0
SHD2_k127_7821898_0 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 329.0
SHD2_k127_7821898_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000001172 216.0
SHD2_k127_7821898_2 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000001252 179.0
SHD2_k127_7832059_0 PFAM luciferase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 355.0
SHD2_k127_7832059_1 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 299.0
SHD2_k127_7832059_2 Crp-like helix-turn-helix domain K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000002738 235.0
SHD2_k127_7832059_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000001589 187.0
SHD2_k127_7832059_4 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000000000000000002126 160.0
SHD2_k127_7832059_5 acetyltransferase K00621 - 2.3.1.4 0.0000000000000000000000000000000000000000008921 168.0
SHD2_k127_7832059_6 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000000000000000000005954 159.0
SHD2_k127_7832059_7 DUF218 domain - - - 0.000000000000000000001051 103.0
SHD2_k127_7832059_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000002663 87.0
SHD2_k127_7832059_9 peptidase K06889 - - 0.0007365 43.0
SHD2_k127_7844816_0 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 583.0
SHD2_k127_7844816_1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile K01241 - 3.2.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 421.0
SHD2_k127_7844816_3 - - - - 0.000000003855 59.0
SHD2_k127_7856778_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 601.0
SHD2_k127_7856778_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 532.0
SHD2_k127_7856778_2 Aldo/keto reductase family - - - 0.00000000000000000000000000009055 115.0
SHD2_k127_7863619_0 Oxidoreductase - - - 7.702e-282 874.0
SHD2_k127_7863619_1 Glycine cleavage T-protein C-terminal barrel domain - - - 5.991e-198 622.0
SHD2_k127_7863619_10 TIR domain - - - 0.00000000000000000000000000000000000000007674 161.0
SHD2_k127_7863619_11 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000008997 134.0
SHD2_k127_7863619_12 HEPN domain - - - 0.000000000000000000000000000000001404 134.0
SHD2_k127_7863619_13 DNA polymerase beta domain protein region - - - 0.00000000000000000000000000002645 123.0
SHD2_k127_7863619_14 PBS lyase HEAT domain protein repeat-containing protein K22221 - - 0.00005705 54.0
SHD2_k127_7863619_2 Thi4 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 602.0
SHD2_k127_7863619_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K14696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003236 288.0
SHD2_k127_7863619_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000003884 257.0
SHD2_k127_7863619_5 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000007952 234.0
SHD2_k127_7863619_6 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000003593 212.0
SHD2_k127_7863619_7 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000000000000000000000000000000000000000000006358 189.0
SHD2_k127_7863619_8 - - - - 0.0000000000000000000000000000000000000000000000001094 193.0
SHD2_k127_7863619_9 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000009979 162.0
SHD2_k127_7892395_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 3.132e-211 661.0
SHD2_k127_7892395_1 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 363.0
SHD2_k127_7892395_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075,K15780 - 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 346.0
SHD2_k127_7892395_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000002856 239.0
SHD2_k127_7892395_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000003367 216.0
SHD2_k127_7892395_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000001561 192.0
SHD2_k127_7892395_6 Septum formation initiator - - - 0.000000000001664 72.0
SHD2_k127_7895677_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 516.0
SHD2_k127_7895677_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000001837 246.0
SHD2_k127_7895677_2 - - - - 0.0000000000000000000000000000000000000000000006312 174.0
SHD2_k127_7895677_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000001113 178.0
SHD2_k127_7914188_0 PFAM carboxyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 546.0
SHD2_k127_7914188_1 PFAM peptidase M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 438.0
SHD2_k127_7914188_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 411.0
SHD2_k127_7914188_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 396.0
SHD2_k127_7914188_4 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000002337 189.0
SHD2_k127_7914188_5 Secretion protein - - - 0.00004705 51.0
SHD2_k127_7942771_0 modification enzyme, MiaB family K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 516.0
SHD2_k127_7942771_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000592 229.0
SHD2_k127_7942771_2 serine threonine protein kinase - - - 0.0000000000000002583 88.0
SHD2_k127_7942771_4 Tetratricopeptide repeat - - - 0.000002468 57.0
SHD2_k127_7958418_0 Sodium:sulfate symporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 533.0
SHD2_k127_7958418_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 351.0
SHD2_k127_7958418_10 Bacterial protein of unknown function (DUF922) - - - 0.0000000000000000006631 94.0
SHD2_k127_7958418_11 - - - - 0.000002413 56.0
SHD2_k127_7958418_2 Belongs to the Pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 327.0
SHD2_k127_7958418_3 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.00000000000000000000000000000000000000000000000000000000000000000000000006319 251.0
SHD2_k127_7958418_4 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000002804 218.0
SHD2_k127_7958418_5 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000000000000001437 195.0
SHD2_k127_7958418_6 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000007404 186.0
SHD2_k127_7958418_7 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000003791 179.0
SHD2_k127_7958418_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000005027 147.0
SHD2_k127_7958418_9 phosphatase (DUF442) - - - 0.0000000000000000000000000000000004346 136.0
SHD2_k127_79587_0 histidine kinase A domain protein - - - 1.341e-251 790.0
SHD2_k127_79587_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 1.767e-236 743.0
SHD2_k127_79587_2 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 312.0
SHD2_k127_79587_3 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000005919 203.0
SHD2_k127_79587_4 Histidine kinase - - - 0.000000000000000000000000000001389 125.0
SHD2_k127_7963764_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.47e-277 863.0
SHD2_k127_7963764_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 597.0
SHD2_k127_7963764_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000009659 162.0
SHD2_k127_7963764_3 DNA-binding transcription factor activity - - - 0.00002662 48.0
SHD2_k127_7967494_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 4.549e-223 699.0
SHD2_k127_7967494_1 Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase K11540 GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905 2.1.3.2,3.5.2.3,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 450.0
SHD2_k127_7967494_2 Cytochrome b/b6/petB K00412,K03888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001449 247.0
SHD2_k127_7967494_3 Rieske [2Fe-2S] domain K03886 - - 0.0000000000000000000000001109 114.0
SHD2_k127_7967494_4 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000001103 93.0
SHD2_k127_7967494_5 Protein of unknown function (DUF1653) K03574 - 3.6.1.55 0.00000000007634 64.0
SHD2_k127_7967494_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00005651 55.0
SHD2_k127_7967494_7 Planctomycete cytochrome C - - - 0.0001304 54.0
SHD2_k127_7967494_8 Copper binding proteins, plastocyanin/azurin family - - - 0.000579 49.0
SHD2_k127_7985185_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 436.0
SHD2_k127_7985185_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 309.0
SHD2_k127_7985185_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007887 257.0
SHD2_k127_7985185_3 sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000146 177.0
SHD2_k127_7985185_4 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000005678 128.0
SHD2_k127_7985185_5 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000001667 105.0
SHD2_k127_8000712_0 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 374.0
SHD2_k127_8000712_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 367.0
SHD2_k127_8000712_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 357.0
SHD2_k127_8000712_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000001022 236.0
SHD2_k127_8000712_4 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000000000000000000000000000000000000000000000003595 200.0
SHD2_k127_8000712_5 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000004606 177.0
SHD2_k127_8000712_6 Virulence activator alpha C-term - - - 0.00000000000000000000000000000000005338 139.0
SHD2_k127_8000712_7 - - - - 0.00000000000000000000009209 103.0
SHD2_k127_800178_0 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 385.0
SHD2_k127_800178_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000356 134.0
SHD2_k127_800178_2 Putative esterase - - - 0.0002103 45.0
SHD2_k127_8007453_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 437.0
SHD2_k127_8007453_1 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005215 271.0
SHD2_k127_8007453_2 Von Willebrand factor type A K07114 - - 0.0001341 45.0
SHD2_k127_8023367_0 PFAM single-stranded nucleic acid binding R3H domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 457.0
SHD2_k127_8023367_1 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.0003912 43.0
SHD2_k127_8038322_0 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000002833 226.0
SHD2_k127_8038322_1 Domain of unknown function (DUF2437) - - - 0.0000000000000003712 81.0
SHD2_k127_8038322_2 COG2199 FOG GGDEF domain - - - 0.00000001469 62.0
SHD2_k127_8092909_0 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 306.0
SHD2_k127_8092909_1 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000003308 173.0
SHD2_k127_8092909_2 - - - - 0.00000000000000000000000000000000000000000003084 163.0
SHD2_k127_8092909_3 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000001453 146.0
SHD2_k127_8092909_4 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000001648 120.0
SHD2_k127_8092909_5 Major facilitator superfamily - - - 0.0000000000000000000000000003768 123.0
SHD2_k127_8147_0 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 509.0
SHD2_k127_8147_1 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 320.0
SHD2_k127_8147_2 COGs COG1653 ABC-type sugar transport system periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000004491 203.0
SHD2_k127_8170915_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 1.652e-246 777.0
SHD2_k127_8170915_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 590.0
SHD2_k127_8170915_4 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000001513 174.0
SHD2_k127_8170915_5 proteolysis K21140 - 3.13.1.6 0.000000000000000000002817 98.0
SHD2_k127_817348_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 369.0
SHD2_k127_817348_1 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 359.0
SHD2_k127_817348_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 329.0
SHD2_k127_817348_3 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 307.0
SHD2_k127_817348_4 amino acid-binding ACT domain protein K04767 - - 0.000000653 53.0
SHD2_k127_8175359_0 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 382.0
SHD2_k127_8175359_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 332.0
SHD2_k127_8175359_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003277 263.0
SHD2_k127_8200190_0 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 549.0
SHD2_k127_8200190_2 - - - - 0.0000000000000000000000000000000000000000000000001409 179.0
SHD2_k127_8200190_3 PFAM DnaJ homologue, subfamily C, member 28, conserved domain - - - 0.00000000000000000005268 93.0
SHD2_k127_822547_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.469e-260 819.0
SHD2_k127_822547_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 451.0
SHD2_k127_822547_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003508 287.0
SHD2_k127_822547_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000003624 240.0
SHD2_k127_822547_4 Pfam:DUF385 - - - 0.0000000000000000000000004903 109.0
SHD2_k127_822547_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000006279 61.0
SHD2_k127_822547_6 Transposase IS200 like K07491 - - 0.00000001476 57.0
SHD2_k127_8251791_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 471.0
SHD2_k127_8251791_1 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 362.0
SHD2_k127_8251791_2 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005362 278.0
SHD2_k127_8251791_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000002858 164.0
SHD2_k127_8251791_4 - - - - 0.000000000000000000049 99.0
SHD2_k127_8251791_5 O-Antigen ligase - - - 0.0000000000000000002322 103.0
SHD2_k127_8251791_6 protein involved in exopolysaccharide biosynthesis - - - 0.000499 50.0
SHD2_k127_8258350_0 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 1.493e-262 813.0
SHD2_k127_8258350_1 PFAM ABC transporter related K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 448.0
SHD2_k127_8258350_2 PFAM regulatory protein, ArsR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008136 265.0
SHD2_k127_8258350_3 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000001559 189.0
SHD2_k127_8259842_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 1.002e-194 619.0
SHD2_k127_8259842_1 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 452.0
SHD2_k127_8259842_2 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000003122 156.0
SHD2_k127_8259842_3 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA - - - 0.000000000000000000000000000000000000000009893 159.0
SHD2_k127_8259842_4 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000000000000000001919 142.0
SHD2_k127_8259842_5 - - - - 0.0000000000000000001323 93.0
SHD2_k127_826385_0 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 350.0
SHD2_k127_826385_1 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000664 236.0
SHD2_k127_826385_2 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000627 228.0
SHD2_k127_826385_3 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.000002897 49.0
SHD2_k127_826385_4 CAAX protease self-immunity - - - 0.00004443 53.0
SHD2_k127_8298303_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 587.0
SHD2_k127_8298303_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 302.0
SHD2_k127_8298303_2 GGDEF domain K13069 - 2.7.7.65 0.00000000000000000000000000000000000000000007734 174.0
SHD2_k127_8298303_3 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000002537 138.0
SHD2_k127_8298303_4 ABC-2 type transporter K01992 - - 0.00000000000000000000000006778 117.0
SHD2_k127_8298303_5 CAAX protease self-immunity K07052 - - 0.000000000000000000000001346 113.0
SHD2_k127_830876_0 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 394.0
SHD2_k127_830876_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001633 256.0
SHD2_k127_8347176_0 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 404.0
SHD2_k127_8347176_1 Two component transcriptional regulator, winged helix family K07669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 378.0
SHD2_k127_8347176_2 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000002053 201.0
SHD2_k127_8378680_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.863e-294 908.0
SHD2_k127_8378680_1 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000000000000000000001382 200.0
SHD2_k127_8378680_2 membrane - - - 0.000000000000000000000000000000000000000000000000000006408 196.0
SHD2_k127_8385289_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 1.032e-194 618.0
SHD2_k127_8385289_1 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 495.0
SHD2_k127_8385289_10 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000001556 235.0
SHD2_k127_8385289_11 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000001385 203.0
SHD2_k127_8385289_12 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.000000000000000000000000000000000002575 141.0
SHD2_k127_8385289_14 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000004817 96.0
SHD2_k127_8385289_15 - - - - 0.0000000000000005916 83.0
SHD2_k127_8385289_16 Hydrogenase maturation protease K03605 - - 0.00000000086 66.0
SHD2_k127_8385289_2 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 461.0
SHD2_k127_8385289_3 TIGRFAM FeS assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 438.0
SHD2_k127_8385289_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 400.0
SHD2_k127_8385289_5 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 341.0
SHD2_k127_8385289_6 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 329.0
SHD2_k127_8385289_7 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 316.0
SHD2_k127_8385289_8 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 312.0
SHD2_k127_8385289_9 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 304.0
SHD2_k127_8403839_0 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 475.0
SHD2_k127_8403839_1 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 459.0
SHD2_k127_8403839_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 430.0
SHD2_k127_8403839_3 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000009823 226.0
SHD2_k127_8412896_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 2.9e-209 677.0
SHD2_k127_8412896_1 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000003299 226.0
SHD2_k127_8412896_2 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 - 2.1.1.182,2.1.1.184 0.000000000000000000000002671 107.0
SHD2_k127_8434331_0 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 395.0
SHD2_k127_8434331_1 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 336.0
SHD2_k127_8434331_2 Cupin 2, conserved barrel domain protein K21700 - - 0.000000000000000000000000000000000000000000000000000000000000004659 218.0
SHD2_k127_8434331_3 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000361 183.0
SHD2_k127_8434331_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000003165 173.0
SHD2_k127_8434331_5 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 0.000000000000000000000000000000000000000001011 170.0
SHD2_k127_861451_0 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K11618 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005754 281.0
SHD2_k127_861451_1 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007686 296.0
SHD2_k127_861451_2 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00000000000000000000000000000001221 127.0
SHD2_k127_928640_0 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 465.0
SHD2_k127_928640_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 381.0
SHD2_k127_928640_10 serine threonine protein kinase - - - 0.000007447 57.0
SHD2_k127_928640_11 - - - - 0.00000878 56.0
SHD2_k127_928640_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 359.0
SHD2_k127_928640_3 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 292.0
SHD2_k127_928640_4 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000008301 215.0
SHD2_k127_928640_5 - - - - 0.0000000000000000000000000000000000000000000000000007867 189.0
SHD2_k127_928640_6 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000001656 173.0
SHD2_k127_928640_7 EamA-like transporter family - - - 0.000000000000000000000000000000002466 140.0
SHD2_k127_928640_8 Transcriptional regulator - - - 0.00000000000000000000000000000005312 127.0
SHD2_k127_928640_9 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000002683 102.0
SHD2_k127_937783_0 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 586.0
SHD2_k127_937783_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 445.0
SHD2_k127_937783_2 Glycosyl transferase, family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 332.0
SHD2_k127_937783_3 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 323.0
SHD2_k127_937783_4 Cytidylyltransferase K07257 - - 0.0000000000000000000000000000000000000000000000000000000000000000002522 238.0
SHD2_k127_937783_5 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000009506 201.0
SHD2_k127_937783_6 membrane-anchored protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000008889 178.0
SHD2_k127_937783_7 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.0000000000000000000000000000000000000004568 156.0
SHD2_k127_937783_8 PFAM EamA-like transporter family - - - 0.00000000000000000000000000000003878 130.0
SHD2_k127_937783_9 inositol 2-dehydrogenase activity K18431 - 2.7.7.82 0.00000000000000000000000000000005074 127.0
SHD2_k127_96792_0 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 386.0
SHD2_k127_96792_1 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 307.0
SHD2_k127_96792_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004592 282.0
SHD2_k127_96792_3 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000006044 222.0
SHD2_k127_96792_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000008504 114.0
SHD2_k127_96792_5 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000002156 107.0
SHD2_k127_96792_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000006695 91.0
SHD2_k127_96792_7 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000003822 86.0
SHD2_k127_993184_0 SMART alpha amylase, catalytic sub domain K01176 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 555.0
SHD2_k127_993184_1 Alpha-amylase domain K01182 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 546.0
SHD2_k127_993184_2 phosphatase activity K07025,K18816 - 2.3.1.82 0.000000000000000000001019 102.0
SHD2_k127_993184_3 FecR protein - - - 0.0003229 52.0