Overview

ID MAG03386
Name SHD3_bin.10
Sample SMP0084
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Micropepsales
Family Micropepsaceae
Genus Rhizomicrobium
Species
Assembly information
Completeness (%) 91.54
Contamination (%) 0.37
GC content (%) 61.0
N50 (bp) 27,240
Genome size (bp) 2,946,901

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2863

Gene name Description KEGG GOs EC E-value Score Sequence
SHD3_k127_1008329_0 Osmosensitive K channel histidine kinase K07646 - 2.7.13.3 1.313e-210 669.0
SHD3_k127_1008329_1 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 325.0
SHD3_k127_1008329_2 DDE domain K07498 - - 0.0000000000000000000000000000000000000000000000000001192 189.0
SHD3_k127_104398_0 PFAM carboxyl transferase K01966 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 6.255e-265 823.0
SHD3_k127_104398_1 MgsA AAA+ ATPase C terminal K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 2.231e-213 669.0
SHD3_k127_104398_10 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 286.0
SHD3_k127_104398_11 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001367 257.0
SHD3_k127_104398_12 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000234 248.0
SHD3_k127_104398_13 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000003268 243.0
SHD3_k127_104398_14 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000145 231.0
SHD3_k127_104398_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000001645 220.0
SHD3_k127_104398_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002995 213.0
SHD3_k127_104398_17 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001267 210.0
SHD3_k127_104398_18 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000009555 209.0
SHD3_k127_104398_19 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000273 208.0
SHD3_k127_104398_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.576e-197 623.0
SHD3_k127_104398_20 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001682 195.0
SHD3_k127_104398_21 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000001129 185.0
SHD3_k127_104398_22 COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.00000000000000000000000000000000000000000000000003039 195.0
SHD3_k127_104398_23 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000006926 182.0
SHD3_k127_104398_24 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000001289 168.0
SHD3_k127_104398_25 Cupin domain - - - 0.0000000000000000000000000000000000000000000003822 181.0
SHD3_k127_104398_26 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000002273 165.0
SHD3_k127_104398_27 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000238 159.0
SHD3_k127_104398_28 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000212 161.0
SHD3_k127_104398_29 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000000001945 142.0
SHD3_k127_104398_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 572.0
SHD3_k127_104398_30 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000002815 132.0
SHD3_k127_104398_31 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000006931 136.0
SHD3_k127_104398_32 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000009575 116.0
SHD3_k127_104398_33 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000007303 117.0
SHD3_k127_104398_34 Beta-lactamase - - - 0.0000000000000000000002898 108.0
SHD3_k127_104398_35 ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000005648 90.0
SHD3_k127_104398_36 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000005023 83.0
SHD3_k127_104398_37 peptidase - - - 0.0000000000000009281 83.0
SHD3_k127_104398_38 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000007223 80.0
SHD3_k127_104398_4 Trypsin K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 482.0
SHD3_k127_104398_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 448.0
SHD3_k127_104398_6 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 429.0
SHD3_k127_104398_7 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 381.0
SHD3_k127_104398_8 RNA pseudouridylate synthase K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 355.0
SHD3_k127_104398_9 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 316.0
SHD3_k127_1055990_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1671.0
SHD3_k127_1055990_1 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 3.865e-273 862.0
SHD3_k127_1055990_10 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 483.0
SHD3_k127_1055990_11 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 454.0
SHD3_k127_1055990_12 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 419.0
SHD3_k127_1055990_13 Peptidase family M13 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 370.0
SHD3_k127_1055990_14 TIGRFAM FeS assembly ATPase SufC K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 367.0
SHD3_k127_1055990_15 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 369.0
SHD3_k127_1055990_16 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 341.0
SHD3_k127_1055990_17 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 339.0
SHD3_k127_1055990_18 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 294.0
SHD3_k127_1055990_19 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 316.0
SHD3_k127_1055990_2 Uncharacterized protein family (UPF0051) K09014 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 2.073e-253 788.0
SHD3_k127_1055990_20 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001543 288.0
SHD3_k127_1055990_21 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001269 269.0
SHD3_k127_1055990_22 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000005518 266.0
SHD3_k127_1055990_23 Belongs to the EutC family K03736 - 4.3.1.7 0.0000000000000000000000000000000000000000000000000000000000000000001543 238.0
SHD3_k127_1055990_24 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000417 218.0
SHD3_k127_1055990_25 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000003512 223.0
SHD3_k127_1055990_26 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000001071 210.0
SHD3_k127_1055990_27 transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000009341 209.0
SHD3_k127_1055990_28 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000002248 188.0
SHD3_k127_1055990_29 NADH ubiquinone oxidoreductase 17.2 kD subunit - - - 0.000000000000000000000000000000000000000000000002212 176.0
SHD3_k127_1055990_3 Ethanolamine ammonia-lyase large subunit K03735 - 4.3.1.7 1.026e-223 702.0
SHD3_k127_1055990_30 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000006823 175.0
SHD3_k127_1055990_31 iron-sulfur transferase activity K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.00000000000000000000000000000000000000000000001536 174.0
SHD3_k127_1055990_32 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000000000000000000001052 169.0
SHD3_k127_1055990_33 Protein of unknown function (DUF1203) - - - 0.00000000000000000000000000000000000000000005811 164.0
SHD3_k127_1055990_34 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.000000000000000000000000000000000000000001119 158.0
SHD3_k127_1055990_35 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000006368 162.0
SHD3_k127_1055990_36 MlaD protein K02067 - - 0.000000000000000000000000000000000000009791 151.0
SHD3_k127_1055990_37 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000009202 148.0
SHD3_k127_1055990_38 DoxX K15977 - - 0.00000000000000000000000000000000003884 139.0
SHD3_k127_1055990_39 Dsba oxidoreductase - - - 0.000000000000000000000000000000002725 139.0
SHD3_k127_1055990_4 Biotin carboxylase C-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 4.325e-223 702.0
SHD3_k127_1055990_40 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000000001367 113.0
SHD3_k127_1055990_41 SnoaL-like polyketide cyclase - - - 0.000000000000000000000003372 108.0
SHD3_k127_1055990_42 TfoX N-terminal domain K07343 - - 0.00000000000000001176 87.0
SHD3_k127_1055990_43 Pentapeptide repeats (9 copies) - - - 0.00000000000000003543 90.0
SHD3_k127_1055990_44 Transcription regulator MerR, DNA binding - - - 0.000000000002234 74.0
SHD3_k127_1055990_45 Protein of unknown function - - - 0.0000001546 63.0
SHD3_k127_1055990_5 peptidase M13 K07386 - - 4.358e-222 708.0
SHD3_k127_1055990_6 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.418e-200 659.0
SHD3_k127_1055990_7 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 5.355e-194 642.0
SHD3_k127_1055990_8 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 550.0
SHD3_k127_1055990_9 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 540.0
SHD3_k127_1067871_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000001713 264.0
SHD3_k127_1067871_1 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000006579 154.0
SHD3_k127_1067871_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000267 62.0
SHD3_k127_1205249_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 6.433e-286 891.0
SHD3_k127_1205249_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.252e-256 805.0
SHD3_k127_1205249_10 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000001461 143.0
SHD3_k127_1205249_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000001141 135.0
SHD3_k127_1205249_12 - - - - 0.000000000000000000000008097 103.0
SHD3_k127_1205249_13 Cation transport regulator K06197 - - 0.00000000000000000000003578 101.0
SHD3_k127_1205249_2 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 556.0
SHD3_k127_1205249_3 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 552.0
SHD3_k127_1205249_4 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 467.0
SHD3_k127_1205249_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 321.0
SHD3_k127_1205249_6 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 299.0
SHD3_k127_1205249_7 Lipoprotein-releasing system ATP-binding protein LolD K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 295.0
SHD3_k127_1205249_8 L,D-transpeptidase catalytic domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001208 288.0
SHD3_k127_1205249_9 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000001843 194.0
SHD3_k127_1217532_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1058.0
SHD3_k127_1217532_1 helicase superfamily c-terminal domain K17675 - 3.6.4.13 3.003e-270 857.0
SHD3_k127_1217532_2 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 389.0
SHD3_k127_1217532_3 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001189 277.0
SHD3_k127_1217532_4 transcriptional regulator K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000005618 232.0
SHD3_k127_1217532_5 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000003755 212.0
SHD3_k127_1217532_6 Staphylococcal nuclease homologue - - - 0.000000000000000000000000000000000000007459 154.0
SHD3_k127_1217532_7 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.0000000000000000000000000839 109.0
SHD3_k127_1217532_8 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000003934 99.0
SHD3_k127_1217532_9 Protein of unknown function (DUF3108) - - - 0.00000000000000000002829 102.0
SHD3_k127_1267684_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 9.541e-293 927.0
SHD3_k127_1267684_1 PQQ enzyme repeat K17760 - 1.1.9.1 1.034e-227 728.0
SHD3_k127_1267684_10 Bacterial regulatory helix-turn-helix protein, lysR family K03566,K17850 - - 0.0000000000000000000000000000000000000000000000000000000006078 213.0
SHD3_k127_1267684_11 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.0000000000000000000000000000000000000000000000000007285 197.0
SHD3_k127_1267684_12 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000152 164.0
SHD3_k127_1267684_13 PilZ domain - - - 0.000000000000000000000001642 111.0
SHD3_k127_1267684_14 sequence-specific DNA binding - - - 0.00001571 57.0
SHD3_k127_1267684_2 Sugar (and other) transporter K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 614.0
SHD3_k127_1267684_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 425.0
SHD3_k127_1267684_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 412.0
SHD3_k127_1267684_5 Putrescine transport system permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 371.0
SHD3_k127_1267684_6 Transcriptional regulatory protein, C terminal K02483 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 351.0
SHD3_k127_1267684_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 326.0
SHD3_k127_1267684_8 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 317.0
SHD3_k127_1267684_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003856 258.0
SHD3_k127_1320149_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 5.338e-320 994.0
SHD3_k127_1320149_1 Proton-conducting membrane transporter - - - 8.504e-286 892.0
SHD3_k127_1320149_10 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 338.0
SHD3_k127_1320149_11 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 295.0
SHD3_k127_1320149_12 Riboflavin synthase alpha chain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 282.0
SHD3_k127_1320149_13 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007699 260.0
SHD3_k127_1320149_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000004626 239.0
SHD3_k127_1320149_15 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000002349 226.0
SHD3_k127_1320149_16 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000000000000000000000000000007842 178.0
SHD3_k127_1320149_17 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000002114 177.0
SHD3_k127_1320149_18 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000001019 171.0
SHD3_k127_1320149_19 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000000000002143 153.0
SHD3_k127_1320149_2 Proton-conducting membrane transporter K12141 - - 2.428e-244 764.0
SHD3_k127_1320149_20 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000002591 153.0
SHD3_k127_1320149_21 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000001081 143.0
SHD3_k127_1320149_22 COG2913 Small protein A (tmRNA-binding) - - - 0.0000000000000000000000000000000007151 136.0
SHD3_k127_1320149_23 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000005319 121.0
SHD3_k127_1320149_24 transcriptional regulator - - - 0.0000000000000000000000000007829 118.0
SHD3_k127_1320149_25 Cytochrome c - - - 0.000000000000000000000000003666 114.0
SHD3_k127_1320149_26 Ubiquinol-cytochrome C chaperone K17662 - - 0.00000000000000000000000002385 115.0
SHD3_k127_1320149_27 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000004082 104.0
SHD3_k127_1320149_28 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000007184 96.0
SHD3_k127_1320149_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 3.29e-228 715.0
SHD3_k127_1320149_30 - - - - 0.000000004342 63.0
SHD3_k127_1320149_31 - - - - 0.00004626 46.0
SHD3_k127_1320149_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.107e-210 660.0
SHD3_k127_1320149_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 520.0
SHD3_k127_1320149_6 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 454.0
SHD3_k127_1320149_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 451.0
SHD3_k127_1320149_8 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 374.0
SHD3_k127_1320149_9 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 354.0
SHD3_k127_1347339_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 5.085e-281 885.0
SHD3_k127_1347339_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 5.991e-267 836.0
SHD3_k127_1347339_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 290.0
SHD3_k127_1347339_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001111 282.0
SHD3_k127_1347339_12 Domain of unknown function (DUF3291) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007822 256.0
SHD3_k127_1347339_13 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001323 238.0
SHD3_k127_1347339_14 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000005029 250.0
SHD3_k127_1347339_15 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000001214 235.0
SHD3_k127_1347339_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000603 195.0
SHD3_k127_1347339_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000008662 164.0
SHD3_k127_1347339_18 MSS3 MSS3 (multicopy suppressors of snf4 deficiency in yeast 3) K13448 GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0010008,GO:0012505,GO:0016020,GO:0016021,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031302,GO:0031303,GO:0031410,GO:0031982,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0097708,GO:0098588,GO:0098805 - 0.000006755 55.0
SHD3_k127_1347339_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 1.01e-232 731.0
SHD3_k127_1347339_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 1.043e-224 704.0
SHD3_k127_1347339_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 3.08e-215 678.0
SHD3_k127_1347339_5 Metallo-beta-lactamase superfamily K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 531.0
SHD3_k127_1347339_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 512.0
SHD3_k127_1347339_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 453.0
SHD3_k127_1347339_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 339.0
SHD3_k127_1347339_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 325.0
SHD3_k127_1387958_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.246e-280 867.0
SHD3_k127_1387958_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.861e-266 823.0
SHD3_k127_1387958_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 429.0
SHD3_k127_1387958_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 376.0
SHD3_k127_1387958_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 287.0
SHD3_k127_1387958_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02113,K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000001413 150.0
SHD3_k127_1387958_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000395 147.0
SHD3_k127_1387958_7 Heparinase II/III-like protein - - - 0.000000000000000000000000002073 116.0
SHD3_k127_1387958_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000105 108.0
SHD3_k127_1389672_0 Pfam Glycosyl transferase family 2 - - - 1.412e-205 665.0
SHD3_k127_1389672_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 382.0
SHD3_k127_1389672_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000001185 164.0
SHD3_k127_1389672_3 Peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000102 151.0
SHD3_k127_1389672_4 Predicted membrane protein (DUF2306) - - - 0.00000000000000000000000000000004102 133.0
SHD3_k127_1434629_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 403.0
SHD3_k127_1434629_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001655 287.0
SHD3_k127_1434629_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000003615 235.0
SHD3_k127_1434629_3 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000004238 205.0
SHD3_k127_1434629_4 Domain of unknown function (DUF202) K00389 - - 0.0000000000000000000000000000002813 127.0
SHD3_k127_1434629_5 Sulfotransferase domain K01014 - 2.8.2.1 0.0000000000000000001457 90.0
SHD3_k127_1434629_6 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.000000004164 65.0
SHD3_k127_143905_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 4.408e-215 676.0
SHD3_k127_143905_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 535.0
SHD3_k127_143905_10 DNA-binding transcription factor activity - - - 0.00000000000000000001357 96.0
SHD3_k127_143905_11 Amidase K01426 - 3.5.1.4 0.000000000000000009972 83.0
SHD3_k127_143905_12 - - - - 0.00000000001505 67.0
SHD3_k127_143905_13 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000004479 58.0
SHD3_k127_143905_2 ATPase (AAA K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 376.0
SHD3_k127_143905_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 332.0
SHD3_k127_143905_4 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003416 246.0
SHD3_k127_143905_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000001283 243.0
SHD3_k127_143905_6 Squalene/phytoene synthase K02291,K18163 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000001741 213.0
SHD3_k127_143905_7 Lysin motif - - - 0.000000000000000000000000000000000000000000000353 175.0
SHD3_k127_143905_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000001993 165.0
SHD3_k127_143905_9 Preprotein translocase subunit K03210 - - 0.00000000000000000000001584 107.0
SHD3_k127_1453909_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.709e-240 764.0
SHD3_k127_1453909_1 lysine 2,3-aminomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 591.0
SHD3_k127_1453909_10 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003251 230.0
SHD3_k127_1453909_11 - - - - 0.000000000000000000000001261 108.0
SHD3_k127_1453909_12 Lipid A Biosynthesis N-terminal domain - - - 0.000000000000000000003744 100.0
SHD3_k127_1453909_13 metal cluster binding K06940,K18475 - - 0.00000000000003591 80.0
SHD3_k127_1453909_14 - - - - 0.00000672 56.0
SHD3_k127_1453909_16 - - - - 0.00003453 51.0
SHD3_k127_1453909_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 385.0
SHD3_k127_1453909_3 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 361.0
SHD3_k127_1453909_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 368.0
SHD3_k127_1453909_5 PFAM Mg2 transporter protein CorA family protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 316.0
SHD3_k127_1453909_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 316.0
SHD3_k127_1453909_7 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000003334 271.0
SHD3_k127_1453909_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000009845 257.0
SHD3_k127_1453909_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000001138 232.0
SHD3_k127_1458402_0 Luciferase-like monooxygenase - - - 1.634e-228 713.0
SHD3_k127_1458402_1 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 617.0
SHD3_k127_1458402_10 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 295.0
SHD3_k127_1458402_11 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 291.0
SHD3_k127_1458402_12 Protein of unknown function (DUF861) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000133 281.0
SHD3_k127_1458402_13 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 273.0
SHD3_k127_1458402_14 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000005881 176.0
SHD3_k127_1458402_15 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000001312 151.0
SHD3_k127_1458402_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 545.0
SHD3_k127_1458402_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 476.0
SHD3_k127_1458402_4 4-coumarate--CoA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 461.0
SHD3_k127_1458402_5 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 413.0
SHD3_k127_1458402_6 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 393.0
SHD3_k127_1458402_7 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 359.0
SHD3_k127_1458402_8 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 351.0
SHD3_k127_1458402_9 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 332.0
SHD3_k127_1463345_0 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 324.0
SHD3_k127_1463345_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005183 279.0
SHD3_k127_1463345_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000195 273.0
SHD3_k127_1463345_3 lipid-transfer protein - - - 0.00000000000000000000000000000000000000000000000051 180.0
SHD3_k127_1463345_5 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00001139 54.0
SHD3_k127_1534694_0 C-terminal, D2-small domain, of ClpB protein K03695 - - 0.0 1286.0
SHD3_k127_1534694_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 449.0
SHD3_k127_1534694_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 314.0
SHD3_k127_1534694_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008899 291.0
SHD3_k127_1534694_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000006295 247.0
SHD3_k127_1534694_5 Domain of unknown function (DUF4167) - - - 0.0000000000000000000007405 101.0
SHD3_k127_1572435_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 9.871e-226 715.0
SHD3_k127_1572435_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 7.357e-209 669.0
SHD3_k127_1572435_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 606.0
SHD3_k127_1572435_3 Glycine cleavage T-protein C-terminal barrel domain K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 419.0
SHD3_k127_1572435_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000003431 169.0
SHD3_k127_1572435_5 CDGSH-type zinc finger. Function unknown. - - - 0.000000000000000000000000000001824 124.0
SHD3_k127_1572435_6 - - - - 0.00000000000007636 78.0
SHD3_k127_1572435_7 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000005754 49.0
SHD3_k127_1589630_0 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 469.0
SHD3_k127_1589630_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001496 285.0
SHD3_k127_1589630_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.0000000000000000000000000000000000000000000000000000001029 205.0
SHD3_k127_1589630_3 - - - - 0.0000000000000000000000000000000000000000000001311 180.0
SHD3_k127_1599982_0 Elongator protein 3, MiaB family, Radical SAM - - - 1.526e-241 769.0
SHD3_k127_1599982_1 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 372.0
SHD3_k127_1599982_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 337.0
SHD3_k127_1599982_3 Outer mitochondrial membrane transport complex protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001933 280.0
SHD3_k127_1599982_4 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006323 279.0
SHD3_k127_1599982_5 InterPro IPR014922 - - - 0.000000000000000000000000000000000000000000002563 169.0
SHD3_k127_1599982_6 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000002872 146.0
SHD3_k127_1599982_7 integral membrane protein - - - 0.00000009658 61.0
SHD3_k127_1599982_8 Uncharacterized protein family, UPF0114 - - - 0.0004488 47.0
SHD3_k127_161168_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 9.567e-272 844.0
SHD3_k127_161168_1 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 1.856e-229 719.0
SHD3_k127_161168_10 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000002344 188.0
SHD3_k127_161168_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000007712 179.0
SHD3_k127_161168_12 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000006759 166.0
SHD3_k127_161168_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000005938 170.0
SHD3_k127_161168_14 Usg-like family - - - 0.00000000000000000000000000000004523 126.0
SHD3_k127_161168_15 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000006127 127.0
SHD3_k127_161168_16 Thioesterase superfamily - - - 0.00000000000000000000000000002918 124.0
SHD3_k127_161168_17 Methyltransferase FkbM domain - - - 0.000000000000000000000001791 117.0
SHD3_k127_161168_18 Dienelactone hydrolase family - - - 0.0006817 46.0
SHD3_k127_161168_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 572.0
SHD3_k127_161168_3 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 559.0
SHD3_k127_161168_4 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 421.0
SHD3_k127_161168_5 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 374.0
SHD3_k127_161168_6 Ribosomal RNA adenine dimethylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005339 275.0
SHD3_k127_161168_7 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002825 267.0
SHD3_k127_161168_8 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000000000000002736 209.0
SHD3_k127_161168_9 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000002748 191.0
SHD3_k127_1618637_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 1.115e-201 634.0
SHD3_k127_1618637_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001506 266.0
SHD3_k127_1618637_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008329 252.0
SHD3_k127_1618637_3 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000001803 160.0
SHD3_k127_1618637_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001215 142.0
SHD3_k127_1625384_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1044.0
SHD3_k127_1625384_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.315e-264 838.0
SHD3_k127_1625384_10 DegT/DnrJ/EryC1/StrS aminotransferase family K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 476.0
SHD3_k127_1625384_11 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 480.0
SHD3_k127_1625384_12 Metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 451.0
SHD3_k127_1625384_13 Electron transfer flavoprotein domain K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 445.0
SHD3_k127_1625384_14 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 434.0
SHD3_k127_1625384_15 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 427.0
SHD3_k127_1625384_16 Aminotransferase class I and II K14261,K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 425.0
SHD3_k127_1625384_17 Domain of unknown function (DUF4175) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 442.0
SHD3_k127_1625384_18 Enoyl-(Acyl carrier protein) reductase K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 403.0
SHD3_k127_1625384_19 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 395.0
SHD3_k127_1625384_2 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 2.486e-247 788.0
SHD3_k127_1625384_20 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 378.0
SHD3_k127_1625384_21 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 368.0
SHD3_k127_1625384_22 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 363.0
SHD3_k127_1625384_23 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 342.0
SHD3_k127_1625384_24 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 322.0
SHD3_k127_1625384_25 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 326.0
SHD3_k127_1625384_26 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 315.0
SHD3_k127_1625384_27 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 310.0
SHD3_k127_1625384_28 COG1592 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006641 262.0
SHD3_k127_1625384_29 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000004508 259.0
SHD3_k127_1625384_3 Belongs to the beta-ketoacyl-ACP synthases family K00647 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 3.813e-199 628.0
SHD3_k127_1625384_30 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000002474 254.0
SHD3_k127_1625384_31 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003382 256.0
SHD3_k127_1625384_32 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005256 248.0
SHD3_k127_1625384_33 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000001215 241.0
SHD3_k127_1625384_34 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000001203 214.0
SHD3_k127_1625384_35 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000005861 212.0
SHD3_k127_1625384_36 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000007978 190.0
SHD3_k127_1625384_38 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000001942 190.0
SHD3_k127_1625384_39 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000218 182.0
SHD3_k127_1625384_4 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 610.0
SHD3_k127_1625384_40 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000000005034 185.0
SHD3_k127_1625384_41 hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000008097 183.0
SHD3_k127_1625384_42 Belongs to the Fur family K09826 - - 0.000000000000000000000000000000000000000000000001328 178.0
SHD3_k127_1625384_43 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000005879 177.0
SHD3_k127_1625384_44 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000004299 173.0
SHD3_k127_1625384_45 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000006299 169.0
SHD3_k127_1625384_46 chorismate mutase - - - 0.00000000000000000000000000000000000000000008375 170.0
SHD3_k127_1625384_47 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000003818 165.0
SHD3_k127_1625384_48 Cell division protein K09811 - - 0.000000000000000000000000000000000000000486 160.0
SHD3_k127_1625384_49 DUF218 domain - - - 0.0000000000000000000000000000000000000005864 155.0
SHD3_k127_1625384_5 Cysteine-rich domain K00113 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 606.0
SHD3_k127_1625384_50 membrane - - - 0.000000000000000000000000000000000005378 142.0
SHD3_k127_1625384_51 DJ-1/PfpI family - - - 0.0000000000000000000000000000000004562 148.0
SHD3_k127_1625384_52 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 0.000000000000000000000000000000776 128.0
SHD3_k127_1625384_53 Bacterial PH domain - - - 0.000000000000000000000000000001764 126.0
SHD3_k127_1625384_54 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000002394 130.0
SHD3_k127_1625384_55 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.00000000000000000000000000001021 123.0
SHD3_k127_1625384_56 Putative adhesin - - - 0.00000000000000000000000000001293 132.0
SHD3_k127_1625384_57 Cytochrome c2 K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000005303 121.0
SHD3_k127_1625384_58 Domain of unknown function (DUF4893) - - - 0.000000000000000000000000006937 119.0
SHD3_k127_1625384_59 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000001669 115.0
SHD3_k127_1625384_6 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 594.0
SHD3_k127_1625384_60 Putative toxin of bacterial toxin-antitoxin pair K09982 - - 0.000000000000000000000000144 109.0
SHD3_k127_1625384_61 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000009596 107.0
SHD3_k127_1625384_62 Cupin 2, conserved barrel - - - 0.000000000000000000000002559 108.0
SHD3_k127_1625384_63 Dodecin K09165 - - 0.00000000000000000000002486 105.0
SHD3_k127_1625384_64 Peptidase propeptide and YPEB domain - - - 0.00000000000000000000003039 105.0
SHD3_k127_1625384_65 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.000000001813 69.0
SHD3_k127_1625384_7 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 549.0
SHD3_k127_1625384_8 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 547.0
SHD3_k127_1625384_9 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 508.0
SHD3_k127_1716820_0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 536.0
SHD3_k127_1716820_1 Homogentisate 1,2-dioxygenase K00451 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0004411,GO:0005488,GO:0005506,GO:0005575,GO:0006082,GO:0006355,GO:0006520,GO:0006558,GO:0006559,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0019219,GO:0019222,GO:0019439,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051213,GO:0051252,GO:0051253,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 1.13.11.5 0.00000000000000000000000000005351 121.0
SHD3_k127_1716820_2 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000001991 111.0
SHD3_k127_1716820_3 - - - - 0.0000000000000000000344 93.0
SHD3_k127_1716820_4 Copper resistance protein D K07245 - - 0.000000000000000524 89.0
SHD3_k127_1716820_5 Copper resistance protein K07156 - - 0.00000000000002858 83.0
SHD3_k127_1717790_0 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 360.0
SHD3_k127_1717790_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 328.0
SHD3_k127_1717790_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002282 257.0
SHD3_k127_1717790_3 Cold shock protein domain K03704 - - 0.000000000000000000000000000000000000000000000000000007296 195.0
SHD3_k127_1717790_5 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.000000000000000000000000000000000000000000000001905 183.0
SHD3_k127_1717790_6 ETC complex I subunit conserved region K00329 - 1.6.5.3 0.000000000000000000000000000000000001563 142.0
SHD3_k127_1717790_7 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000003764 141.0
SHD3_k127_1717790_8 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000127 63.0
SHD3_k127_1781823_0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 1.159e-251 786.0
SHD3_k127_1781823_1 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 429.0
SHD3_k127_1781823_2 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 374.0
SHD3_k127_1781823_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 300.0
SHD3_k127_1781823_4 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002944 269.0
SHD3_k127_1781823_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000003056 257.0
SHD3_k127_1781823_6 Methyltransferase small domain K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000000005294 193.0
SHD3_k127_1781823_7 Putative prokaryotic signal transducing protein - - - 0.000000000001996 80.0
SHD3_k127_1781823_8 amine dehydrogenase activity - - - 0.00006046 46.0
SHD3_k127_1785385_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1485.0
SHD3_k127_1785385_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1073.0
SHD3_k127_1785385_10 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 502.0
SHD3_k127_1785385_11 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 477.0
SHD3_k127_1785385_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14980 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 474.0
SHD3_k127_1785385_13 pyridine nucleotide-disulfide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 430.0
SHD3_k127_1785385_14 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 389.0
SHD3_k127_1785385_15 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 378.0
SHD3_k127_1785385_16 Transcriptional regulatory protein, C terminal K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 370.0
SHD3_k127_1785385_17 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 372.0
SHD3_k127_1785385_18 ABC transporter permease K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 348.0
SHD3_k127_1785385_19 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 354.0
SHD3_k127_1785385_2 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 5.757e-272 874.0
SHD3_k127_1785385_20 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 347.0
SHD3_k127_1785385_21 ABC transporter K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 297.0
SHD3_k127_1785385_22 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 296.0
SHD3_k127_1785385_23 Phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 299.0
SHD3_k127_1785385_24 Nucleotidyl transferase K00966,K00992 - 2.7.7.13,2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 291.0
SHD3_k127_1785385_25 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 291.0
SHD3_k127_1785385_26 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007982 278.0
SHD3_k127_1785385_27 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000004677 258.0
SHD3_k127_1785385_28 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000085 255.0
SHD3_k127_1785385_29 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001407 251.0
SHD3_k127_1785385_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 2.596e-263 816.0
SHD3_k127_1785385_30 Histidine kinase K11357 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000008614 241.0
SHD3_k127_1785385_31 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000009994 227.0
SHD3_k127_1785385_32 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000001244 219.0
SHD3_k127_1785385_33 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000002304 212.0
SHD3_k127_1785385_34 NAD(P)H-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000003249 181.0
SHD3_k127_1785385_35 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000693 183.0
SHD3_k127_1785385_36 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000003974 175.0
SHD3_k127_1785385_37 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.00000000000000000000000000000000000000000000001122 174.0
SHD3_k127_1785385_38 ferredoxin K04755 - - 0.000000000000000000000000000000000000000000001229 166.0
SHD3_k127_1785385_39 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000005019 163.0
SHD3_k127_1785385_4 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 1.193e-238 774.0
SHD3_k127_1785385_40 Threonylcarbamoyl adenosine biosynthesis protein TsaE K07102 - 2.7.1.221 0.00000000000000000000000000000000000000129 153.0
SHD3_k127_1785385_41 PAS domain - - - 0.000000000000000000000000000000000000001462 153.0
SHD3_k127_1785385_42 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000001378 147.0
SHD3_k127_1785385_43 Glutathione peroxidase K02199 - - 0.000000000000000000000000000000000000187 150.0
SHD3_k127_1785385_44 Protein of unknown function (DUF2794) - - - 0.0000000000000000000000000000000000003739 145.0
SHD3_k127_1785385_45 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000004183 124.0
SHD3_k127_1785385_46 Serine kinase of the HPr protein, regulates carbohydrate metabolism - - - 0.00000000000000000000000001174 115.0
SHD3_k127_1785385_47 Ankyrin repeat - - - 0.000000000000000000000005411 110.0
SHD3_k127_1785385_48 MerR, DNA binding K13639 - - 0.0000000000000000000003996 103.0
SHD3_k127_1785385_49 glyoxalase III activity - - - 0.000000000000000000003949 97.0
SHD3_k127_1785385_5 FtsX-like permease family K02004 - - 3.952e-229 740.0
SHD3_k127_1785385_50 TIGRFAM phosphocarrier, HPr family K11189 - - 0.00000000000000000001563 100.0
SHD3_k127_1785385_51 Domain of unknown function (DUF4340) - - - 0.00000000000000000002154 104.0
SHD3_k127_1785385_52 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000002581 77.0
SHD3_k127_1785385_54 - - - - 0.00000000004211 70.0
SHD3_k127_1785385_55 PilZ domain - - - 0.000003005 54.0
SHD3_k127_1785385_56 smart pdz dhr glgf K04771,K08372 - 3.4.21.107 0.0003497 47.0
SHD3_k127_1785385_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 2.173e-212 670.0
SHD3_k127_1785385_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.625e-202 637.0
SHD3_k127_1785385_8 PAS fold - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 566.0
SHD3_k127_1785385_9 ABC-type uncharacterized transport system K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 546.0
SHD3_k127_1840265_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.625e-267 830.0
SHD3_k127_1840265_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 3.723e-203 644.0
SHD3_k127_1840265_2 Peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 318.0
SHD3_k127_1840265_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 293.0
SHD3_k127_1840265_4 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 291.0
SHD3_k127_1840265_5 protein conserved in bacteria K09798 - - 0.0000000000000000000000000000000000000000000000000000000000005215 219.0
SHD3_k127_1840265_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000008771 146.0
SHD3_k127_1840265_7 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000001633 98.0
SHD3_k127_1840265_8 Transcriptional regulator - - - 0.0000000000000000001971 93.0
SHD3_k127_1877155_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 3.429e-254 797.0
SHD3_k127_1877155_1 Acyl-CoA dehydrogenase N terminal - - - 3.824e-253 794.0
SHD3_k127_1877155_10 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 295.0
SHD3_k127_1877155_11 extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001272 288.0
SHD3_k127_1877155_12 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000007625 245.0
SHD3_k127_1877155_13 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000004004 239.0
SHD3_k127_1877155_14 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000003088 225.0
SHD3_k127_1877155_15 Protein of unknown function (DUF2585) - - - 0.0000000000000000000000000000000000000000000000000166 188.0
SHD3_k127_1877155_16 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000001524 108.0
SHD3_k127_1877155_17 - - - - 0.0000000001896 66.0
SHD3_k127_1877155_18 - - - - 0.0000007273 59.0
SHD3_k127_1877155_2 COG4166 ABC-type oligopeptide transport system, periplasmic component K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 508.0
SHD3_k127_1877155_3 Acyl-CoA synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 482.0
SHD3_k127_1877155_4 COG4166 ABC-type oligopeptide transport system, periplasmic component K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 455.0
SHD3_k127_1877155_5 COG4166 ABC-type oligopeptide transport system, periplasmic component K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 452.0
SHD3_k127_1877155_6 Binding-protein-dependent transport system inner membrane component K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 417.0
SHD3_k127_1877155_7 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 416.0
SHD3_k127_1877155_8 Aspartyl protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 349.0
SHD3_k127_1877155_9 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 313.0
SHD3_k127_1897150_0 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 370.0
SHD3_k127_1897150_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 318.0
SHD3_k127_1897150_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000007326 208.0
SHD3_k127_1897150_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000002592 197.0
SHD3_k127_1897150_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000008666 187.0
SHD3_k127_1897150_5 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000008889 100.0
SHD3_k127_1897150_6 Flp Fap pilin component K02651 - - 0.000002439 51.0
SHD3_k127_1908375_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1199.0
SHD3_k127_1908375_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 5.119e-318 980.0
SHD3_k127_1908375_10 FAD dependent oxidoreductase K09471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 357.0
SHD3_k127_1908375_11 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 341.0
SHD3_k127_1908375_12 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 327.0
SHD3_k127_1908375_13 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 329.0
SHD3_k127_1908375_14 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 317.0
SHD3_k127_1908375_15 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 317.0
SHD3_k127_1908375_16 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 320.0
SHD3_k127_1908375_17 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002056 273.0
SHD3_k127_1908375_18 hydrolases of HD superfamily K06952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001196 252.0
SHD3_k127_1908375_19 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000003335 228.0
SHD3_k127_1908375_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 1.962e-227 714.0
SHD3_k127_1908375_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000002251 237.0
SHD3_k127_1908375_21 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000026 214.0
SHD3_k127_1908375_22 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000005528 209.0
SHD3_k127_1908375_23 Cupin domain - - - 0.00000000000000000000000000000000000000000000002737 177.0
SHD3_k127_1908375_24 - - - - 0.0000000000000000000000000000000000000000002059 171.0
SHD3_k127_1908375_25 - - - - 0.00000000000000000000000000000000000008684 152.0
SHD3_k127_1908375_26 protein tyrosine phosphatase - - - 0.0000000000000000000000000000000000001198 147.0
SHD3_k127_1908375_27 MAPEG family - - - 0.00000000000000000000000000000000006993 138.0
SHD3_k127_1908375_28 Succinate dehydrogenase Fumarate reductase K00241 - - 0.0000000000000000000000000000000005268 145.0
SHD3_k127_1908375_29 Cell Wall Hydrolase - - - 0.00000000000000000000000000008147 124.0
SHD3_k127_1908375_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 555.0
SHD3_k127_1908375_30 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000002377 111.0
SHD3_k127_1908375_31 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.00000000000000000000000009725 117.0
SHD3_k127_1908375_32 - - - - 0.000000000000000000000000667 112.0
SHD3_k127_1908375_33 Protein of unknown function (DUF3126) - - - 0.000000000000000000004894 94.0
SHD3_k127_1908375_34 - - - - 0.00000361 53.0
SHD3_k127_1908375_35 17 kDa outer membrane surface antigen - - - 0.000007815 54.0
SHD3_k127_1908375_4 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K16872 - 2.3.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 526.0
SHD3_k127_1908375_5 Quinolinate synthetase A protein K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 491.0
SHD3_k127_1908375_6 belongs to the nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 394.0
SHD3_k127_1908375_7 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 383.0
SHD3_k127_1908375_8 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 364.0
SHD3_k127_1908375_9 Serine acetyltransferase, N-terminal K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 364.0
SHD3_k127_1916338_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 3.998e-195 618.0
SHD3_k127_1916338_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 512.0
SHD3_k127_1916338_10 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000009871 235.0
SHD3_k127_1916338_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000005729 219.0
SHD3_k127_1916338_12 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000007908 221.0
SHD3_k127_1916338_13 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000333 190.0
SHD3_k127_1916338_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.0000000000000000000000000000000000000000000002663 184.0
SHD3_k127_1916338_15 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000202 70.0
SHD3_k127_1916338_16 phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000017 75.0
SHD3_k127_1916338_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 492.0
SHD3_k127_1916338_3 COG0625 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 433.0
SHD3_k127_1916338_4 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 400.0
SHD3_k127_1916338_5 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 324.0
SHD3_k127_1916338_6 S4 RNA-binding domain K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 322.0
SHD3_k127_1916338_7 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172 288.0
SHD3_k127_1916338_8 COG0861 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001155 264.0
SHD3_k127_1916338_9 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005575 236.0
SHD3_k127_194200_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 7.395e-266 833.0
SHD3_k127_194200_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 355.0
SHD3_k127_194200_2 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000336 273.0
SHD3_k127_194200_3 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000002068 188.0
SHD3_k127_194200_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000008084 169.0
SHD3_k127_194200_5 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000003823 120.0
SHD3_k127_194200_6 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000001977 117.0
SHD3_k127_194200_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000006274 96.0
SHD3_k127_194200_8 - - - - 0.000000001292 65.0
SHD3_k127_1948783_0 Belongs to the enoyl-CoA hydratase isomerase family K00022,K07514 - 1.1.1.35,4.2.1.17,5.3.3.8 0.0 1104.0
SHD3_k127_1948783_1 ABC transporter K15738 - - 2.517e-283 879.0
SHD3_k127_1948783_10 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000002562 138.0
SHD3_k127_1948783_11 MlaC protein K07323 - - 0.000000000000000000000000000000001044 139.0
SHD3_k127_1948783_2 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 402.0
SHD3_k127_1948783_3 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 360.0
SHD3_k127_1948783_4 KR domain K00218 - 1.3.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009027 357.0
SHD3_k127_1948783_5 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 332.0
SHD3_k127_1948783_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 313.0
SHD3_k127_1948783_7 Methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 313.0
SHD3_k127_1948783_8 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000002088 212.0
SHD3_k127_1948783_9 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000003692 150.0
SHD3_k127_1992711_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0 1145.0
SHD3_k127_1992711_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1006.0
SHD3_k127_1992711_10 Imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 309.0
SHD3_k127_1992711_11 HAD-hyrolase-like K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 297.0
SHD3_k127_1992711_12 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000169 282.0
SHD3_k127_1992711_13 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005699 269.0
SHD3_k127_1992711_14 COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006205 265.0
SHD3_k127_1992711_15 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000006713 263.0
SHD3_k127_1992711_16 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000001409 248.0
SHD3_k127_1992711_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002223 256.0
SHD3_k127_1992711_18 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000004184 209.0
SHD3_k127_1992711_19 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000008342 192.0
SHD3_k127_1992711_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.397e-293 925.0
SHD3_k127_1992711_20 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000003029 183.0
SHD3_k127_1992711_21 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - 0.00000000000000000000000000000000000000000000002231 179.0
SHD3_k127_1992711_22 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000003149 174.0
SHD3_k127_1992711_23 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000000000000000000000000000008217 176.0
SHD3_k127_1992711_24 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000003857 150.0
SHD3_k127_1992711_25 DNA repair protein MmcB-like - - - 0.0000000000000000000000000000000000007483 144.0
SHD3_k127_1992711_26 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000001185 138.0
SHD3_k127_1992711_27 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000008439 138.0
SHD3_k127_1992711_28 ASCH - - - 0.000000000000000000000000000007962 122.0
SHD3_k127_1992711_29 PFAM acid phosphatase (Class B) - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000007994 112.0
SHD3_k127_1992711_3 Participates in both transcription termination and antitermination K02600 - - 2.324e-237 744.0
SHD3_k127_1992711_30 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate - - - 0.00000000000000000000001502 106.0
SHD3_k127_1992711_31 YGGT family K02221 - - 0.00000000000000000004592 94.0
SHD3_k127_1992711_32 Protein conserved in bacteria - - - 0.0000000000000000007561 89.0
SHD3_k127_1992711_33 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000007696 93.0
SHD3_k127_1992711_34 Belongs to the UPF0235 family K09131 - - 0.000000000000000004941 94.0
SHD3_k127_1992711_36 PFAM YCII-related - - - 0.00002136 52.0
SHD3_k127_1992711_4 S-adenosylmethionine synthetase, C-terminal domain K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.53e-211 663.0
SHD3_k127_1992711_5 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 9.768e-203 638.0
SHD3_k127_1992711_6 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 551.0
SHD3_k127_1992711_7 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 421.0
SHD3_k127_1992711_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 380.0
SHD3_k127_1992711_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 351.0
SHD3_k127_2024490_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1055.0
SHD3_k127_2024490_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000182 256.0
SHD3_k127_2024490_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000005182 231.0
SHD3_k127_2024490_3 nUDIX hydrolase K01518,K08296 - 3.6.1.17 0.0000000000000000000000000000000000007295 145.0
SHD3_k127_2024490_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000001209 90.0
SHD3_k127_2039384_0 AMP-binding enzyme K12508 - 6.2.1.34 1.679e-254 798.0
SHD3_k127_2039384_1 acyl-CoA dehydrogenase - - - 1.844e-212 666.0
SHD3_k127_2039384_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000003892 196.0
SHD3_k127_2039384_11 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000008222 198.0
SHD3_k127_2039384_12 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000008283 186.0
SHD3_k127_2039384_13 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000001412 190.0
SHD3_k127_2039384_14 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000006423 176.0
SHD3_k127_2039384_15 MOSC domain - - - 0.000000000000000000000000000000000000005288 149.0
SHD3_k127_2039384_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000001019 143.0
SHD3_k127_2039384_17 COG3631 Ketosteroid isomerase-related protein K06893 - - 0.00007684 52.0
SHD3_k127_2039384_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038,K21977 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 566.0
SHD3_k127_2039384_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 518.0
SHD3_k127_2039384_4 Cysteine synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 499.0
SHD3_k127_2039384_5 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 340.0
SHD3_k127_2039384_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 331.0
SHD3_k127_2039384_7 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 317.0
SHD3_k127_2039384_8 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 317.0
SHD3_k127_2039384_9 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000004585 258.0
SHD3_k127_2053293_0 ATPases associated with a variety of cellular activities K02003,K05685 - - 5.789e-268 842.0
SHD3_k127_2053293_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.756e-263 821.0
SHD3_k127_2053293_10 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 473.0
SHD3_k127_2053293_11 Rieske 2Fe-2S domain protein K16319,K18242 - 1.14.12.1,1.14.13.172 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 455.0
SHD3_k127_2053293_12 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 451.0
SHD3_k127_2053293_13 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 430.0
SHD3_k127_2053293_14 HlyD family secretion protein K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 410.0
SHD3_k127_2053293_15 Gentisate 1,2-dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 396.0
SHD3_k127_2053293_16 ABC transporter, ATP-binding protein K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 387.0
SHD3_k127_2053293_17 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 381.0
SHD3_k127_2053293_18 cytochrome P450 K15468 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 387.0
SHD3_k127_2053293_19 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009027 390.0
SHD3_k127_2053293_2 PQQ enzyme repeat K17760 - 1.1.9.1 9.319e-232 739.0
SHD3_k127_2053293_20 4-hydroxy-tetrahydrodipicolinate synthase K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 381.0
SHD3_k127_2053293_21 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 370.0
SHD3_k127_2053293_22 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 352.0
SHD3_k127_2053293_23 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 339.0
SHD3_k127_2053293_24 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 342.0
SHD3_k127_2053293_25 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 334.0
SHD3_k127_2053293_26 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 321.0
SHD3_k127_2053293_27 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 311.0
SHD3_k127_2053293_28 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 312.0
SHD3_k127_2053293_29 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 316.0
SHD3_k127_2053293_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.208e-221 701.0
SHD3_k127_2053293_30 Histidyl-tRNA synthetase K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 317.0
SHD3_k127_2053293_32 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003658 277.0
SHD3_k127_2053293_33 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000001501 270.0
SHD3_k127_2053293_34 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000003065 262.0
SHD3_k127_2053293_35 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000393 243.0
SHD3_k127_2053293_36 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001436 251.0
SHD3_k127_2053293_37 TfuA-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004548 243.0
SHD3_k127_2053293_38 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003677 231.0
SHD3_k127_2053293_39 Cytidylate kinase K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000001349 228.0
SHD3_k127_2053293_4 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 562.0
SHD3_k127_2053293_40 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000000000000000004355 226.0
SHD3_k127_2053293_41 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000001977 201.0
SHD3_k127_2053293_42 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000004881 204.0
SHD3_k127_2053293_43 Hsp20/alpha crystallin family K04080 - - 0.000000000000000000000000000000000000000000000000002674 185.0
SHD3_k127_2053293_44 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000000000000009531 167.0
SHD3_k127_2053293_45 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000005152 168.0
SHD3_k127_2053293_46 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000008454 153.0
SHD3_k127_2053293_47 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000001204 146.0
SHD3_k127_2053293_48 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000000000000182 144.0
SHD3_k127_2053293_49 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000165 146.0
SHD3_k127_2053293_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 563.0
SHD3_k127_2053293_50 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000004413 134.0
SHD3_k127_2053293_51 Ring hydroxylating beta subunit K16320 - 1.14.12.1 0.000000000000000000000000002442 119.0
SHD3_k127_2053293_52 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000005579 116.0
SHD3_k127_2053293_53 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000003264 109.0
SHD3_k127_2053293_54 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000002274 103.0
SHD3_k127_2053293_55 - - - - 0.00000000001688 68.0
SHD3_k127_2053293_56 Flp pilus assembly protein, pilin Flp K02651 - - 0.00000000009285 64.0
SHD3_k127_2053293_57 Protein of unknown function (DUF1150) - - - 0.0000000004917 64.0
SHD3_k127_2053293_58 OstA-like protein K09774 - - 0.0000000006397 68.0
SHD3_k127_2053293_59 Histidine kinase - - - 0.00000001654 61.0
SHD3_k127_2053293_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 547.0
SHD3_k127_2053293_60 PAS domain - - - 0.00000001913 63.0
SHD3_k127_2053293_61 Cupin domain - - - 0.00000002141 57.0
SHD3_k127_2053293_62 - - - - 0.00000003652 55.0
SHD3_k127_2053293_64 Protein of unknown function (FYDLN_acid) - - - 0.000004756 56.0
SHD3_k127_2053293_65 Cupin domain - - - 0.0003634 47.0
SHD3_k127_2053293_7 chorismate binding enzyme K13950 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 546.0
SHD3_k127_2053293_8 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 530.0
SHD3_k127_2053293_9 4Fe-4S double cluster binding domain K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 483.0
SHD3_k127_20703_0 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 1.487e-245 768.0
SHD3_k127_20703_1 Ring hydroxylating alpha subunit (catalytic domain) - - - 1.41e-213 671.0
SHD3_k127_20703_10 DUF35 OB-fold domain, acyl-CoA-associated K07549 - - 0.000000000000000000000000000000000000006211 150.0
SHD3_k127_20703_2 acetyl-coa acetyltransferase - - - 1.999e-207 649.0
SHD3_k127_20703_3 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 524.0
SHD3_k127_20703_4 Short-chain dehydrogenase reductase (SDR) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 396.0
SHD3_k127_20703_5 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 346.0
SHD3_k127_20703_6 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 323.0
SHD3_k127_20703_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001718 255.0
SHD3_k127_20703_8 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000004806 237.0
SHD3_k127_20703_9 - - - - 0.000000000000000000000000000000000000002923 153.0
SHD3_k127_2095726_0 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 302.0
SHD3_k127_2095726_1 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005726 269.0
SHD3_k127_2095726_2 methyltransferase - - - 0.0000000000000000000000000000000000000004344 162.0
SHD3_k127_2095726_3 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000001884 157.0
SHD3_k127_2095726_4 - - - - 0.0000000000000000002618 93.0
SHD3_k127_2095726_5 membrane - - - 0.00000000000000007632 89.0
SHD3_k127_2095726_6 membrane - - - 0.0000000001984 67.0
SHD3_k127_2095726_7 sequence-specific DNA binding - - - 0.00000007156 57.0
SHD3_k127_2139949_0 Required for chromosome condensation and partitioning K03529 - - 5.261e-314 998.0
SHD3_k127_2139949_1 GAD domain K01876 - 6.1.1.12 5.297e-284 885.0
SHD3_k127_2139949_10 Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002305 284.0
SHD3_k127_2139949_11 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007642 280.0
SHD3_k127_2139949_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004585 266.0
SHD3_k127_2139949_13 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002435 264.0
SHD3_k127_2139949_14 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000614 245.0
SHD3_k127_2139949_15 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000002824 226.0
SHD3_k127_2139949_16 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001797 229.0
SHD3_k127_2139949_17 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000513 218.0
SHD3_k127_2139949_18 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000002488 199.0
SHD3_k127_2139949_19 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000132 199.0
SHD3_k127_2139949_2 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 541.0
SHD3_k127_2139949_20 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000001822 173.0
SHD3_k127_2139949_21 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000009025 155.0
SHD3_k127_2139949_22 Belongs to the HesB IscA family K13628,K15724 - - 0.000000000000000000000000000000000000001804 149.0
SHD3_k127_2139949_23 COG1651 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000003708 155.0
SHD3_k127_2139949_24 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000007836 148.0
SHD3_k127_2139949_25 cellulose binding - - - 0.0000000000000000000000000000000000006022 145.0
SHD3_k127_2139949_26 SnoaL-like domain - - - 0.0000000000000000000000000000000005759 134.0
SHD3_k127_2139949_27 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000002769 124.0
SHD3_k127_2139949_28 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000003509 123.0
SHD3_k127_2139949_29 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000001433 113.0
SHD3_k127_2139949_3 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 541.0
SHD3_k127_2139949_30 Sporulation related domain - - - 0.000000000000000000000000007676 121.0
SHD3_k127_2139949_31 KR domain - - - 0.00000000000000000000000007695 109.0
SHD3_k127_2139949_32 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) K02109 - - 0.000000000000000000000004822 108.0
SHD3_k127_2139949_33 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000000000009978 93.0
SHD3_k127_2139949_34 ThiS family K03636 - - 0.00000000004425 67.0
SHD3_k127_2139949_35 Protein of unknown function (DUF721) - - - 0.00000000008311 69.0
SHD3_k127_2139949_36 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000004084 66.0
SHD3_k127_2139949_37 - - - - 0.000001425 55.0
SHD3_k127_2139949_38 Psort location CytoplasmicMembrane, score - - - 0.000003514 54.0
SHD3_k127_2139949_39 SpoIIAA-like - - - 0.00001419 54.0
SHD3_k127_2139949_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 484.0
SHD3_k127_2139949_5 deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 445.0
SHD3_k127_2139949_6 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 426.0
SHD3_k127_2139949_7 COG1194 A G-specific DNA glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 398.0
SHD3_k127_2139949_8 Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 387.0
SHD3_k127_2139949_9 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 344.0
SHD3_k127_2199975_0 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 1.145e-230 717.0
SHD3_k127_2199975_1 Belongs to the peptidase M16 family K07263 - - 5.128e-227 736.0
SHD3_k127_2281631_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1397.0
SHD3_k127_2281631_1 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 3e-323 999.0
SHD3_k127_2281631_10 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000000000000000000000003585 198.0
SHD3_k127_2281631_11 - - - - 0.000000000000000000000000000000000000000000000000005469 199.0
SHD3_k127_2281631_12 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000007421 145.0
SHD3_k127_2281631_13 Protein of unknown function (DUF3297) - - - 0.0000000000000000000000000000000001215 138.0
SHD3_k127_2281631_14 - - - - 0.000000000000000000000000000000004326 137.0
SHD3_k127_2281631_15 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.000000000000000000003763 94.0
SHD3_k127_2281631_16 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000001096 92.0
SHD3_k127_2281631_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 1.661e-284 889.0
SHD3_k127_2281631_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.972e-196 620.0
SHD3_k127_2281631_4 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 555.0
SHD3_k127_2281631_5 NAD(P)H-binding K15894 - 4.2.1.115 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 488.0
SHD3_k127_2281631_6 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 462.0
SHD3_k127_2281631_7 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 360.0
SHD3_k127_2281631_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001485 268.0
SHD3_k127_2281631_9 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002802 240.0
SHD3_k127_2291807_0 Transposase - - - 1.959e-246 763.0
SHD3_k127_2291807_1 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 294.0
SHD3_k127_2291807_2 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000001215 189.0
SHD3_k127_2291807_3 transcriptional regulator, XRE family K07726 - - 0.000000000000000000002404 94.0
SHD3_k127_2291807_4 - - - - 0.0000000000000008973 83.0
SHD3_k127_2357251_0 Cys/Met metabolism PLP-dependent enzyme K00643 - 2.3.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 578.0
SHD3_k127_2357251_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 571.0
SHD3_k127_2357251_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000009735 211.0
SHD3_k127_2357251_3 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000005113 154.0
SHD3_k127_2357251_4 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000008517 95.0
SHD3_k127_2357251_5 - - - - 0.0000001214 55.0
SHD3_k127_2372157_0 Homogentisate 1,2-dioxygenase K00451 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0004411,GO:0005488,GO:0005506,GO:0005575,GO:0006082,GO:0006355,GO:0006520,GO:0006558,GO:0006559,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0019219,GO:0019222,GO:0019439,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051213,GO:0051252,GO:0051253,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 464.0
SHD3_k127_2372157_1 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 458.0
SHD3_k127_2372157_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 306.0
SHD3_k127_2372157_3 Maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003083 274.0
SHD3_k127_2372157_4 PFAM Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000002901 198.0
SHD3_k127_2372157_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000004183 151.0
SHD3_k127_2372157_6 PFAM alpha beta hydrolase K00641 - 2.3.1.31 0.00000000000001583 73.0
SHD3_k127_2413016_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.576e-314 971.0
SHD3_k127_2413016_1 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 2.443e-295 916.0
SHD3_k127_2413016_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 599.0
SHD3_k127_2413016_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 551.0
SHD3_k127_2413016_4 PFAM tRNA synthetase, class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 481.0
SHD3_k127_2413016_5 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001481 253.0
SHD3_k127_2413016_6 unsaturated fatty acid biosynthetic process K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000001742 115.0
SHD3_k127_2492760_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 6.855e-257 796.0
SHD3_k127_2492760_1 acyl-CoA transferases carnitine dehydratase K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 471.0
SHD3_k127_2492760_2 Sodium/hydrogen exchanger family K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 349.0
SHD3_k127_2492760_3 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 338.0
SHD3_k127_2492760_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007768 288.0
SHD3_k127_2492760_5 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000003358 182.0
SHD3_k127_2492760_6 Stringent starvation protein B K09985 - - 0.00000000000000000000000000000000000000000001357 168.0
SHD3_k127_2492760_7 Ribbon-helix-helix domain - - - 0.00000000000004233 79.0
SHD3_k127_2492760_9 amine dehydrogenase activity - - - 0.0004509 46.0
SHD3_k127_2498554_0 ABC transporter C-terminal domain K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 2.181e-253 794.0
SHD3_k127_2498554_1 ABC transporter - - - 1.644e-196 627.0
SHD3_k127_2498554_10 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000357 192.0
SHD3_k127_2498554_11 MlaD protein K02067,K06192 - - 0.000000000000000000000000000000000000000000001271 176.0
SHD3_k127_2498554_12 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000551 126.0
SHD3_k127_2498554_13 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000008538 130.0
SHD3_k127_2498554_14 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000008766 85.0
SHD3_k127_2498554_2 Phosphoinositide phospholipase C, Ca2+-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 400.0
SHD3_k127_2498554_3 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 347.0
SHD3_k127_2498554_4 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 344.0
SHD3_k127_2498554_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 329.0
SHD3_k127_2498554_6 KR domain K18009 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 327.0
SHD3_k127_2498554_7 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 301.0
SHD3_k127_2498554_8 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.000000000000000000000000000000000000000000000000000000000000000000009379 243.0
SHD3_k127_2498554_9 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000001327 207.0
SHD3_k127_2527241_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.952e-222 696.0
SHD3_k127_2527241_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 5.421e-216 689.0
SHD3_k127_2527241_10 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 360.0
SHD3_k127_2527241_11 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 340.0
SHD3_k127_2527241_12 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 320.0
SHD3_k127_2527241_13 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 298.0
SHD3_k127_2527241_14 Anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 286.0
SHD3_k127_2527241_15 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001171 289.0
SHD3_k127_2527241_16 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004366 261.0
SHD3_k127_2527241_17 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000191 259.0
SHD3_k127_2527241_18 protein conserved in bacteria K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000303 253.0
SHD3_k127_2527241_19 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000644 187.0
SHD3_k127_2527241_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 611.0
SHD3_k127_2527241_20 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000002658 163.0
SHD3_k127_2527241_21 membrane - - - 0.000000000000000000005187 100.0
SHD3_k127_2527241_22 unfolded protein binding K06142 - - 0.00000000003276 72.0
SHD3_k127_2527241_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 572.0
SHD3_k127_2527241_4 Competence protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 489.0
SHD3_k127_2527241_5 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 456.0
SHD3_k127_2527241_6 PFAM aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 447.0
SHD3_k127_2527241_7 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 419.0
SHD3_k127_2527241_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 395.0
SHD3_k127_2527241_9 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 399.0
SHD3_k127_254050_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.366e-236 741.0
SHD3_k127_254050_1 Binding-protein-dependent transport systems inner membrane component K02050 - - 3.46e-233 736.0
SHD3_k127_254050_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 590.0
SHD3_k127_254050_3 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 587.0
SHD3_k127_254050_4 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 585.0
SHD3_k127_254050_5 Rod shape-determining protein (MreB) K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 482.0
SHD3_k127_254050_6 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003619 262.0
SHD3_k127_254050_7 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000002591 222.0
SHD3_k127_254050_8 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000355 175.0
SHD3_k127_2540613_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 2.744e-207 652.0
SHD3_k127_2540613_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 541.0
SHD3_k127_2540613_2 4-coumarate--CoA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 499.0
SHD3_k127_2540613_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 475.0
SHD3_k127_2540613_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000003363 237.0
SHD3_k127_256678_0 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002658 253.0
SHD3_k127_256678_1 TIM-barrel signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000003233 223.0
SHD3_k127_256678_2 Protein of unknown function (DUF861) - - - 0.0000000000000000000000000000000000000000000000000000000288 198.0
SHD3_k127_256678_3 Resolvase, N terminal domain K06400 - - 0.00000000000000000000000001675 113.0
SHD3_k127_256678_4 ABC transporter - - - 0.0000000000000000001041 90.0
SHD3_k127_256678_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000003921 75.0
SHD3_k127_256678_6 HNH endonuclease K07451,K07453 - - 0.000002343 51.0
SHD3_k127_256678_7 - - - - 0.00002197 50.0
SHD3_k127_2579113_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 9.735e-221 694.0
SHD3_k127_2579113_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 533.0
SHD3_k127_2579113_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 536.0
SHD3_k127_2579113_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 304.0
SHD3_k127_2579113_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 290.0
SHD3_k127_2579113_5 Class II aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008122 236.0
SHD3_k127_2579113_6 Bacterial transcriptional regulator K05818 - - 0.000000000000000000000000000000000000000000000001734 183.0
SHD3_k127_2579113_7 Belongs to the UPF0306 family K09979 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000001307 169.0
SHD3_k127_2579113_8 Cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000000006384 83.0
SHD3_k127_260097_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18989 - - 0.0 1062.0
SHD3_k127_260097_1 DNA helicase K03654 - 3.6.4.12 1.892e-244 769.0
SHD3_k127_260097_10 Cold shock protein domain K03704 - - 0.000000000000000000000000000000000000000000001014 173.0
SHD3_k127_260097_11 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000004535 171.0
SHD3_k127_260097_12 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000006596 169.0
SHD3_k127_260097_13 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000001026 156.0
SHD3_k127_260097_2 ABC transporter transmembrane region K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 3.304e-226 718.0
SHD3_k127_260097_3 Belongs to the IlvD Edd family K22186 - 4.2.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 503.0
SHD3_k127_260097_4 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 497.0
SHD3_k127_260097_5 Taurine catabolism dioxygenase TauD, TfdA family K03119,K22303 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 383.0
SHD3_k127_260097_6 Gluconolaconase K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 355.0
SHD3_k127_260097_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 304.0
SHD3_k127_260097_8 Barrel-sandwich domain of CusB or HlyD membrane-fusion K18990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 301.0
SHD3_k127_260097_9 Uncharacterized BCR, YaiI/YqxD family COG1671 K09768 - - 0.00000000000000000000000000000000000000000000000000000000006789 207.0
SHD3_k127_2713151_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 5.47e-223 713.0
SHD3_k127_2713151_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001888 269.0
SHD3_k127_2713151_2 P-aminobenzoate N-oxygenase AurF - - - 0.000000000009657 66.0
SHD3_k127_276535_0 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 383.0
SHD3_k127_276535_1 Lipoprotein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000003632 211.0
SHD3_k127_2853433_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1158.0
SHD3_k127_2853433_1 Carboxyl transferase domain K01969 - 6.4.1.4 3.904e-269 837.0
SHD3_k127_2853433_2 carboxylase K01965,K01968 - 6.4.1.3,6.4.1.4 5.241e-227 720.0
SHD3_k127_2853433_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 310.0
SHD3_k127_2853433_4 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000001809 230.0
SHD3_k127_2853433_5 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000001569 193.0
SHD3_k127_2853433_6 Beta-lactamase enzyme family K01286 - 3.4.16.4 0.00000000000000000000000000000000000000007017 165.0
SHD3_k127_2853433_7 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000005806 130.0
SHD3_k127_2853433_8 Protein of unknown function (DUF1489) - - - 0.000000000000000000007624 93.0
SHD3_k127_2853433_9 Protein of unknown function (DUF1489) - - - 0.000000000000000002415 86.0
SHD3_k127_2855090_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 4.951e-228 715.0
SHD3_k127_2855090_1 NADP-dependent oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 449.0
SHD3_k127_2855090_2 Bacterial transcription activator, effector binding domain K13652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 304.0
SHD3_k127_2855090_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001332 262.0
SHD3_k127_2855090_4 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000104 213.0
SHD3_k127_2855090_5 - - - - 0.0000000801 61.0
SHD3_k127_2895767_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1140.0
SHD3_k127_2895767_1 DEAD/H associated K03724 - - 0.0 1085.0
SHD3_k127_2895767_10 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 549.0
SHD3_k127_2895767_11 And related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 530.0
SHD3_k127_2895767_12 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 493.0
SHD3_k127_2895767_13 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 464.0
SHD3_k127_2895767_14 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 445.0
SHD3_k127_2895767_15 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 438.0
SHD3_k127_2895767_16 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 450.0
SHD3_k127_2895767_17 Alpha beta hydrolase K01253,K08253 - 2.7.10.2,3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 432.0
SHD3_k127_2895767_18 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 423.0
SHD3_k127_2895767_19 Taurine catabolism dioxygenase TauD, TfdA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 424.0
SHD3_k127_2895767_2 Luciferase-like monooxygenase - - - 1.628e-252 783.0
SHD3_k127_2895767_20 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 420.0
SHD3_k127_2895767_21 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 381.0
SHD3_k127_2895767_22 (Fe-S) oxidoreductase K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 335.0
SHD3_k127_2895767_23 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 304.0
SHD3_k127_2895767_24 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 307.0
SHD3_k127_2895767_25 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 291.0
SHD3_k127_2895767_26 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009441 275.0
SHD3_k127_2895767_27 Thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004633 272.0
SHD3_k127_2895767_28 infection protein K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008828 265.0
SHD3_k127_2895767_29 Calcineurin-like phosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004186 254.0
SHD3_k127_2895767_3 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 1.045e-251 788.0
SHD3_k127_2895767_30 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001354 250.0
SHD3_k127_2895767_31 Sel1-like repeats. K07126,K13582 - - 0.000000000000000000000000000000000000000000000000000000000000000000005154 264.0
SHD3_k127_2895767_32 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000000000000000000000592 233.0
SHD3_k127_2895767_33 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000002557 233.0
SHD3_k127_2895767_34 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000005999 219.0
SHD3_k127_2895767_35 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000004263 220.0
SHD3_k127_2895767_36 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000002224 218.0
SHD3_k127_2895767_37 Putative transmembrane protein (Alph_Pro_TM) - - - 0.0000000000000000000000000000000000000000000000000000001924 210.0
SHD3_k127_2895767_38 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000004074 201.0
SHD3_k127_2895767_39 probably involved in intracellular septation - - - 0.0000000000000000000000000000000002475 138.0
SHD3_k127_2895767_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K18688 - 6.2.1.42 4.564e-214 676.0
SHD3_k127_2895767_40 Thioesterase superfamily - - - 0.000000000000000000000000000000001901 135.0
SHD3_k127_2895767_41 phosphoglycerate mutase - - - 0.000000000000000000000000000001468 131.0
SHD3_k127_2895767_42 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000001244 118.0
SHD3_k127_2895767_43 Tetratricopeptide repeat - - - 0.000000000000000000000000002703 126.0
SHD3_k127_2895767_44 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000557 119.0
SHD3_k127_2895767_45 LUD domain K00782 - - 0.000000000000000000000002185 117.0
SHD3_k127_2895767_46 Thioesterase superfamily - - - 0.0000000000000000000008003 100.0
SHD3_k127_2895767_47 probably involved in intracellular septation - - - 0.000000000000000008536 91.0
SHD3_k127_2895767_48 membrane - - - 0.000000000000003879 78.0
SHD3_k127_2895767_49 - - - - 0.0000000000001017 76.0
SHD3_k127_2895767_5 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 1.815e-213 674.0
SHD3_k127_2895767_50 Cysteine-rich secretory protein family - - - 0.0000000001048 70.0
SHD3_k127_2895767_51 Protein of unknown function (DUF962) - - - 0.0000004342 58.0
SHD3_k127_2895767_53 phosphinothricin N-acetyltransferase activity K18816 - 2.3.1.82 0.000008044 52.0
SHD3_k127_2895767_54 WHG domain - - - 0.0003189 51.0
SHD3_k127_2895767_55 - - - - 0.0004035 45.0
SHD3_k127_2895767_6 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 610.0
SHD3_k127_2895767_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 587.0
SHD3_k127_2895767_8 LUD domain K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 551.0
SHD3_k127_2895767_9 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 542.0
SHD3_k127_2919513_0 Bacterial protein of unknown function (DUF885) - - - 5.605e-210 673.0
SHD3_k127_2919513_1 ferredoxin--NADP reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 492.0
SHD3_k127_2919513_10 Histidine kinase K07647 - 2.7.13.3 0.000000000002113 72.0
SHD3_k127_2919513_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007472 268.0
SHD3_k127_2919513_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000006961 264.0
SHD3_k127_2919513_4 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002478 254.0
SHD3_k127_2919513_5 methyltransferase - - - 0.00000000000000000000000000000000000000001916 160.0
SHD3_k127_2919513_6 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000001632 149.0
SHD3_k127_2919513_7 FR47-like protein - - - 0.000000000000000000000000000000009724 137.0
SHD3_k127_2919513_8 transmembrane signaling receptor activity - - - 0.0000000000000000000000000000001619 142.0
SHD3_k127_2919513_9 histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000004801 87.0
SHD3_k127_2930084_0 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 1.903e-243 771.0
SHD3_k127_2930084_1 elongation factor G K02355 - - 2.331e-241 764.0
SHD3_k127_2930084_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005634 252.0
SHD3_k127_2930084_11 Transcriptional - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000009827 213.0
SHD3_k127_2930084_12 TPM domain - - - 0.00000000000000000000000000000000000000000000000000006751 201.0
SHD3_k127_2930084_13 PAS domain - - - 0.00000000000000007492 88.0
SHD3_k127_2930084_14 membrane K08988 - - 0.0000000000001164 81.0
SHD3_k127_2930084_15 - - - - 0.0000000003606 69.0
SHD3_k127_2930084_2 Major Facilitator - - - 6.404e-210 666.0
SHD3_k127_2930084_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 452.0
SHD3_k127_2930084_4 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 428.0
SHD3_k127_2930084_5 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 337.0
SHD3_k127_2930084_6 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 319.0
SHD3_k127_2930084_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007714 281.0
SHD3_k127_2930084_8 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002768 266.0
SHD3_k127_2930084_9 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007109 268.0
SHD3_k127_2934122_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1091.0
SHD3_k127_2934122_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.154e-256 813.0
SHD3_k127_2934122_10 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 409.0
SHD3_k127_2934122_11 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 403.0
SHD3_k127_2934122_12 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 361.0
SHD3_k127_2934122_13 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 318.0
SHD3_k127_2934122_14 alpha/beta hydrolase fold K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 321.0
SHD3_k127_2934122_15 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 315.0
SHD3_k127_2934122_16 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 291.0
SHD3_k127_2934122_17 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 295.0
SHD3_k127_2934122_18 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009334 284.0
SHD3_k127_2934122_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002135 278.0
SHD3_k127_2934122_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 7.057e-239 759.0
SHD3_k127_2934122_20 Ndr family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001917 274.0
SHD3_k127_2934122_21 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000002725 257.0
SHD3_k127_2934122_22 Diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003344 263.0
SHD3_k127_2934122_23 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000002348 223.0
SHD3_k127_2934122_24 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000006676 222.0
SHD3_k127_2934122_25 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000001092 220.0
SHD3_k127_2934122_26 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000734 208.0
SHD3_k127_2934122_27 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000000000586 199.0
SHD3_k127_2934122_28 nuclease activity K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000002541 193.0
SHD3_k127_2934122_29 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000003379 177.0
SHD3_k127_2934122_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 8.225e-227 712.0
SHD3_k127_2934122_30 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000007061 159.0
SHD3_k127_2934122_31 RNA polymerase Rpb6 K03060 - 2.7.7.6 0.0000000000000000000000000000004601 126.0
SHD3_k127_2934122_32 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000002201 124.0
SHD3_k127_2934122_33 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000003507 121.0
SHD3_k127_2934122_34 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000002361 111.0
SHD3_k127_2934122_35 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000002752 92.0
SHD3_k127_2934122_36 protein conserved in bacteria K09984 - - 0.00000000000000000008614 91.0
SHD3_k127_2934122_37 Protein of unknown function (DUF1453) - - - 0.00002547 53.0
SHD3_k127_2934122_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.496e-221 703.0
SHD3_k127_2934122_5 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 576.0
SHD3_k127_2934122_6 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 519.0
SHD3_k127_2934122_7 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 498.0
SHD3_k127_2934122_8 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 467.0
SHD3_k127_2934122_9 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 434.0
SHD3_k127_2937513_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1174.0
SHD3_k127_2937513_1 argininosuccinate synthase activity K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.153e-225 702.0
SHD3_k127_2937513_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 460.0
SHD3_k127_2937513_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 357.0
SHD3_k127_2937513_4 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001801 265.0
SHD3_k127_2937513_5 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000006955 214.0
SHD3_k127_2937513_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000009305 197.0
SHD3_k127_2938979_0 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 515.0
SHD3_k127_2938979_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 501.0
SHD3_k127_2938979_2 MaoC like domain K14449 GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 494.0
SHD3_k127_2938979_3 AFG1-like ATPase K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 403.0
SHD3_k127_2938979_4 FAD binding domain K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 374.0
SHD3_k127_2938979_5 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 368.0
SHD3_k127_2938979_6 Belongs to the HpcH HpaI aldolase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 361.0
SHD3_k127_2938979_7 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 313.0
SHD3_k127_2938979_8 Protein of unknown function (DUF992) - - - 0.00000000000000000000000000000001385 141.0
SHD3_k127_2996134_0 AAA domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 418.0
SHD3_k127_2996134_1 - - - - 0.00000000000000000000000000000002176 132.0
SHD3_k127_3010378_0 Acetyltransferase (GNAT) domain K01905,K09181,K22224 - 6.2.1.13 3.136e-297 936.0
SHD3_k127_3010378_1 Thymidine phosphorylase K00758 - 2.4.2.4 5.715e-194 617.0
SHD3_k127_3010378_10 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000003263 188.0
SHD3_k127_3010378_11 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000131 187.0
SHD3_k127_3010378_12 Universal stress protein family - - - 0.0000000000000000000000000000000000000000003382 170.0
SHD3_k127_3010378_13 Universal stress protein family - - - 0.000000000000000000000000000000000000000007464 166.0
SHD3_k127_3010378_14 Universal stress protein - - - 0.000000000000000000000000000002103 132.0
SHD3_k127_3010378_15 Caspase domain - - - 0.0000000000000000000000001188 118.0
SHD3_k127_3010378_16 4-hydroxy-3-methylbut-2-enyl diphosphate reductase - - - 0.0000000000000000005022 89.0
SHD3_k127_3010378_17 Response regulator receiver domain - - - 0.000000000000000007688 88.0
SHD3_k127_3010378_18 - - - - 0.000000000004501 71.0
SHD3_k127_3010378_19 Cytochrome C oxidase, cbb3-type, subunit III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000008911 52.0
SHD3_k127_3010378_2 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 593.0
SHD3_k127_3010378_3 PAS fold K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 389.0
SHD3_k127_3010378_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 346.0
SHD3_k127_3010378_5 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 300.0
SHD3_k127_3010378_6 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001968 286.0
SHD3_k127_3010378_7 Flavodoxin-like fold K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000183 209.0
SHD3_k127_3010378_8 helix_turn_helix, cAMP Regulatory protein K01420,K15861 - - 0.00000000000000000000000000000000000000000000000000001369 199.0
SHD3_k127_3010378_9 - - - - 0.000000000000000000000000000000000000000000000000001733 187.0
SHD3_k127_3034635_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K05939 - 2.3.1.40,6.2.1.20 5.467e-217 686.0
SHD3_k127_3034635_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 491.0
SHD3_k127_3034635_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 316.0
SHD3_k127_3034635_3 Competence-damaged protein K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000004407 220.0
SHD3_k127_3034635_4 oligoketide cyclase lipid transport protein K18588 - - 0.000000000000000000000000000000000009976 147.0
SHD3_k127_3034635_5 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000001483 127.0
SHD3_k127_3043086_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1076.0
SHD3_k127_3043086_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000001695 218.0
SHD3_k127_3043086_2 Acyltransferase family - - - 0.00000000000000000000000000000000000009678 153.0
SHD3_k127_3043086_3 Trypsin - - - 0.0001602 53.0
SHD3_k127_3129609_0 Dehydrogenase K15371 - 1.4.1.2 0.0 1410.0
SHD3_k127_3129609_1 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1295.0
SHD3_k127_3129609_10 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 512.0
SHD3_k127_3129609_11 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 506.0
SHD3_k127_3129609_12 YHS domain K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 497.0
SHD3_k127_3129609_13 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 491.0
SHD3_k127_3129609_14 SMART AAA ATPase K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 428.0
SHD3_k127_3129609_15 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 423.0
SHD3_k127_3129609_16 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 402.0
SHD3_k127_3129609_17 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 397.0
SHD3_k127_3129609_18 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 365.0
SHD3_k127_3129609_19 KR domain K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 356.0
SHD3_k127_3129609_2 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1224.0
SHD3_k127_3129609_20 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 355.0
SHD3_k127_3129609_21 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 357.0
SHD3_k127_3129609_22 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 313.0
SHD3_k127_3129609_23 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 304.0
SHD3_k127_3129609_24 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 297.0
SHD3_k127_3129609_25 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001162 287.0
SHD3_k127_3129609_26 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003442 280.0
SHD3_k127_3129609_27 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004574 260.0
SHD3_k127_3129609_28 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006711 249.0
SHD3_k127_3129609_29 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003147 249.0
SHD3_k127_3129609_3 GMC oxidoreductase K00108 - 1.1.99.1 1.87e-242 759.0
SHD3_k127_3129609_30 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006622 241.0
SHD3_k127_3129609_31 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000001 233.0
SHD3_k127_3129609_32 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000002313 217.0
SHD3_k127_3129609_33 Polyhydroxyalkanoate synthesis repressor - - - 0.00000000000000000000000000000000000000000000000000000000001353 212.0
SHD3_k127_3129609_34 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000000000002101 216.0
SHD3_k127_3129609_35 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000000000000000003857 193.0
SHD3_k127_3129609_36 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000003527 198.0
SHD3_k127_3129609_37 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000001506 181.0
SHD3_k127_3129609_38 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000009684 175.0
SHD3_k127_3129609_39 Periplasmic protein thiol disulfide oxidoreductase K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000008858 171.0
SHD3_k127_3129609_4 ABC transporter transmembrane region K06147 - - 2.158e-200 641.0
SHD3_k127_3129609_40 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000494 166.0
SHD3_k127_3129609_41 phosphinothricin N-acetyltransferase activity K03825 - - 0.00000000000000000000000000000000000000000003346 166.0
SHD3_k127_3129609_42 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000006176 163.0
SHD3_k127_3129609_43 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000005548 169.0
SHD3_k127_3129609_44 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000002988 158.0
SHD3_k127_3129609_45 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000001218 159.0
SHD3_k127_3129609_46 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000007819 156.0
SHD3_k127_3129609_47 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000004082 151.0
SHD3_k127_3129609_48 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000001562 143.0
SHD3_k127_3129609_49 PilZ domain - - - 0.000000000000000000000000000000000002862 146.0
SHD3_k127_3129609_5 Belongs to the thiolase family K00626 - 2.3.1.9 6.127e-196 617.0
SHD3_k127_3129609_50 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000003854 142.0
SHD3_k127_3129609_51 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000004624 147.0
SHD3_k127_3129609_52 Belongs to the bacterial histone-like protein family K03530 - - 0.00000000000000000000000000000004243 128.0
SHD3_k127_3129609_53 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000002942 126.0
SHD3_k127_3129609_54 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - 0.00000000000000000000000000005308 129.0
SHD3_k127_3129609_55 Domain of unknown function (DUF4442) - - - 0.00000000000000000000002059 108.0
SHD3_k127_3129609_56 YjbR - - - 0.0000000000000000000000219 106.0
SHD3_k127_3129609_57 - - - - 0.00000000000000000003478 97.0
SHD3_k127_3129609_58 Class II flagellar assembly regulator - - - 0.00000000000000000004293 96.0
SHD3_k127_3129609_59 PAS domain - - - 0.00000000000000000006486 98.0
SHD3_k127_3129609_6 peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01322 - 3.4.21.26 7.441e-194 627.0
SHD3_k127_3129609_60 - - - - 0.00000000000000000007004 101.0
SHD3_k127_3129609_61 - - - - 0.00000000000000001821 89.0
SHD3_k127_3129609_62 Domain of unknown function (DUF4908) - - - 0.000004092 58.0
SHD3_k127_3129609_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 598.0
SHD3_k127_3129609_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 561.0
SHD3_k127_3129609_9 MiaB-like tRNA modifying enzyme K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 529.0
SHD3_k127_3174103_0 dioxygenase K11159 - - 7.251e-257 797.0
SHD3_k127_3174103_1 FAD dependent oxidoreductase K07137 - - 8.231e-257 803.0
SHD3_k127_3174103_10 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 498.0
SHD3_k127_3174103_11 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 481.0
SHD3_k127_3174103_12 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 446.0
SHD3_k127_3174103_13 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 416.0
SHD3_k127_3174103_14 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 388.0
SHD3_k127_3174103_15 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 385.0
SHD3_k127_3174103_16 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 362.0
SHD3_k127_3174103_17 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 354.0
SHD3_k127_3174103_18 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 345.0
SHD3_k127_3174103_19 proteins, homologs of microcin C7 resistance protein MccF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 325.0
SHD3_k127_3174103_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 7.187e-228 710.0
SHD3_k127_3174103_20 VirC1 protein K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 303.0
SHD3_k127_3174103_21 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 295.0
SHD3_k127_3174103_22 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007797 276.0
SHD3_k127_3174103_23 Major Facilitator Superfamily K08169 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001496 273.0
SHD3_k127_3174103_24 WHG domain - - - 0.000000000000000000000000000000000000000000000001106 187.0
SHD3_k127_3174103_25 PFAM GumN family protein - - - 0.00000000000000000000000000000000000000000000001206 184.0
SHD3_k127_3174103_26 Psort location OuterMembrane, score 9.92 K03772 - 5.2.1.8 0.00000000000000000000000000000000008873 139.0
SHD3_k127_3174103_28 endonuclease containing a URI domain K07461 - - 0.000000000000000004259 89.0
SHD3_k127_3174103_3 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 1.953e-209 665.0
SHD3_k127_3174103_4 acyl-CoA dehydrogenase - - - 1.093e-204 643.0
SHD3_k127_3174103_5 Mur ligase family, catalytic domain - - - 5.976e-198 626.0
SHD3_k127_3174103_6 Belongs to the thiolase family K00626 - 2.3.1.9 1.155e-195 616.0
SHD3_k127_3174103_7 TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 602.0
SHD3_k127_3174103_8 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 505.0
SHD3_k127_3174103_9 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 504.0
SHD3_k127_3199212_0 DNA polymerase alpha chain like domain K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1262.0
SHD3_k127_3199212_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 7.197e-254 796.0
SHD3_k127_3199212_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 285.0
SHD3_k127_3199212_11 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003356 280.0
SHD3_k127_3199212_12 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000007639 237.0
SHD3_k127_3199212_13 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001211 217.0
SHD3_k127_3199212_14 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000001006 147.0
SHD3_k127_3199212_15 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000002798 128.0
SHD3_k127_3199212_16 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000006971 75.0
SHD3_k127_3199212_17 Protein of unknown function (DUF1467) - - - 0.0000003463 54.0
SHD3_k127_3199212_2 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 574.0
SHD3_k127_3199212_3 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 499.0
SHD3_k127_3199212_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 432.0
SHD3_k127_3199212_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 377.0
SHD3_k127_3199212_6 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 377.0
SHD3_k127_3199212_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 368.0
SHD3_k127_3199212_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 359.0
SHD3_k127_3199212_9 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 364.0
SHD3_k127_3247269_0 Flavin-binding monooxygenase-like - - - 2.557e-316 976.0
SHD3_k127_3247269_1 amine dehydrogenase activity - - - 3.165e-314 990.0
SHD3_k127_3247269_10 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 535.0
SHD3_k127_3247269_11 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 484.0
SHD3_k127_3247269_12 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 463.0
SHD3_k127_3247269_13 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 455.0
SHD3_k127_3247269_14 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 442.0
SHD3_k127_3247269_15 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 428.0
SHD3_k127_3247269_16 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 413.0
SHD3_k127_3247269_17 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 404.0
SHD3_k127_3247269_18 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 404.0
SHD3_k127_3247269_19 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 400.0
SHD3_k127_3247269_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 5.558e-277 860.0
SHD3_k127_3247269_20 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 389.0
SHD3_k127_3247269_21 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 393.0
SHD3_k127_3247269_22 carboxylic ester hydrolase activity K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 384.0
SHD3_k127_3247269_23 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 364.0
SHD3_k127_3247269_24 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 351.0
SHD3_k127_3247269_25 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 351.0
SHD3_k127_3247269_26 Glutathione S-transferase, C-terminal domain K00799,K03599 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 340.0
SHD3_k127_3247269_27 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 277.0
SHD3_k127_3247269_28 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000001518 239.0
SHD3_k127_3247269_29 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000001162 233.0
SHD3_k127_3247269_3 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01576,K01652 - 2.2.1.6,4.1.1.7 1.639e-248 775.0
SHD3_k127_3247269_30 BetI-type transcriptional repressor, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000001051 219.0
SHD3_k127_3247269_31 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000006347 215.0
SHD3_k127_3247269_32 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000003686 207.0
SHD3_k127_3247269_33 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000000000000000001874 192.0
SHD3_k127_3247269_34 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000002109 194.0
SHD3_k127_3247269_35 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000003171 188.0
SHD3_k127_3247269_36 Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000000000000000000000000000005641 177.0
SHD3_k127_3247269_37 Protease prsW family - - - 0.000000000000000000000000000000000000000000000002342 186.0
SHD3_k127_3247269_38 PFAM Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000004758 177.0
SHD3_k127_3247269_39 Secretion protein K01993 - - 0.00000000000000000000000000000000000000000000002138 181.0
SHD3_k127_3247269_4 cytochrome P450 - - - 8.093e-221 691.0
SHD3_k127_3247269_40 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000005256 178.0
SHD3_k127_3247269_41 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000008493 169.0
SHD3_k127_3247269_42 protein conserved in bacteria K09973 - - 0.000000000000000000000000000000000000000000001271 176.0
SHD3_k127_3247269_43 CHAP domain - - - 0.000000000000000000000000000000000007613 145.0
SHD3_k127_3247269_44 Isochorismatase family - - - 0.00000000000000000000000000000000002512 142.0
SHD3_k127_3247269_45 Domain of unknown function (DUF4180) - - - 0.0000000000000000000000000000000001305 138.0
SHD3_k127_3247269_46 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000002361 135.0
SHD3_k127_3247269_47 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000153 134.0
SHD3_k127_3247269_48 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000007097 138.0
SHD3_k127_3247269_49 nitric oxide dioxygenase activity - - - 0.00000000000000000000000000000001227 132.0
SHD3_k127_3247269_5 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 8.078e-210 663.0
SHD3_k127_3247269_50 - - - - 0.0000000000000000000000000000002517 130.0
SHD3_k127_3247269_51 Rubredoxin - - - 0.000000000000000000000000000003082 121.0
SHD3_k127_3247269_52 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000001224 104.0
SHD3_k127_3247269_54 Sulfurtransferase TusA K04085 - - 0.0000000000004753 72.0
SHD3_k127_3247269_55 PAS domain - - - 0.00000000004244 70.0
SHD3_k127_3247269_56 PAS domain - - - 0.000004676 56.0
SHD3_k127_3247269_57 PAS domain - - - 0.00006615 51.0
SHD3_k127_3247269_6 Transport of potassium into the cell K03549 - - 3.034e-199 638.0
SHD3_k127_3247269_7 FAD linked oxidases, C-terminal domain - - - 1.384e-198 629.0
SHD3_k127_3247269_8 K+ potassium transporter - - - 3.764e-197 634.0
SHD3_k127_3247269_9 AMP-binding enzyme K08746,K08749 - 6.2.1.3 3.273e-196 628.0
SHD3_k127_324944_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 555.0
SHD3_k127_324944_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000003874 199.0
SHD3_k127_324944_2 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000003526 80.0
SHD3_k127_324944_3 - - - - 0.00000003677 55.0
SHD3_k127_3283316_0 phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.928e-283 894.0
SHD3_k127_3283316_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K03921,K20087 - 1.14.19.11,1.14.19.2,1.14.19.26,1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 569.0
SHD3_k127_3283316_10 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001765 276.0
SHD3_k127_3283316_11 phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005459 254.0
SHD3_k127_3283316_12 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001007 247.0
SHD3_k127_3283316_13 Pfam Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000002575 236.0
SHD3_k127_3283316_14 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000001451 214.0
SHD3_k127_3283316_15 COG1956 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000000000000000004345 211.0
SHD3_k127_3283316_16 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000000000000000000000000000000000000000000000000009616 195.0
SHD3_k127_3283316_17 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0000000000000000000000000000000000000000002255 160.0
SHD3_k127_3283316_18 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000002302 163.0
SHD3_k127_3283316_19 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000009792 164.0
SHD3_k127_3283316_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 497.0
SHD3_k127_3283316_20 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000002052 151.0
SHD3_k127_3283316_21 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000001712 141.0
SHD3_k127_3283316_22 Sel1-like repeats. K07126,K13582 - - 0.00000000000000000000000000002602 138.0
SHD3_k127_3283316_23 protein conserved in bacteria K09973 - - 0.0000000000000000000000000004657 125.0
SHD3_k127_3283316_24 - - - - 0.000000000000000000000007425 112.0
SHD3_k127_3283316_25 oxidoreductase - - - 0.000000000000000003782 87.0
SHD3_k127_3283316_26 - - - - 0.00000000000000008629 85.0
SHD3_k127_3283316_28 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000001494 70.0
SHD3_k127_3283316_29 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 - - - 0.000000001233 61.0
SHD3_k127_3283316_3 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 486.0
SHD3_k127_3283316_4 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 413.0
SHD3_k127_3283316_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 385.0
SHD3_k127_3283316_6 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 372.0
SHD3_k127_3283316_7 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 357.0
SHD3_k127_3283316_8 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 338.0
SHD3_k127_3283316_9 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
SHD3_k127_3342147_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1346.0
SHD3_k127_3342147_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1151.0
SHD3_k127_3342147_10 Phosphoglucose isomerase K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 395.0
SHD3_k127_3342147_11 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 377.0
SHD3_k127_3342147_12 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 379.0
SHD3_k127_3342147_13 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 356.0
SHD3_k127_3342147_14 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 355.0
SHD3_k127_3342147_15 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 350.0
SHD3_k127_3342147_16 Putative diguanylate phosphodiesterase K13593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 314.0
SHD3_k127_3342147_17 taurine catabolism dioxygenase K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 298.0
SHD3_k127_3342147_18 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000134 284.0
SHD3_k127_3342147_19 sugar phosphatases of the HAD superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007501 274.0
SHD3_k127_3342147_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 1.152e-249 783.0
SHD3_k127_3342147_20 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000001596 249.0
SHD3_k127_3342147_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000001043 228.0
SHD3_k127_3342147_22 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000007302 209.0
SHD3_k127_3342147_23 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000009484 206.0
SHD3_k127_3342147_24 Acetyltransferase (GNAT) domain K03830 - - 0.00000000000000000000000000000000000000000000000000000009565 199.0
SHD3_k127_3342147_25 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.00000000000000000000000000000000000000000000006505 172.0
SHD3_k127_3342147_26 acetyltransferase - - - 0.000000000000000000000000000000000000000000004236 172.0
SHD3_k127_3342147_27 ferredoxin K04755 - - 0.00000000000000000000000000000000000000000007324 162.0
SHD3_k127_3342147_28 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000006991 154.0
SHD3_k127_3342147_29 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000006683 117.0
SHD3_k127_3342147_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.047e-224 712.0
SHD3_k127_3342147_30 - - - - 0.000000000000000000000005796 108.0
SHD3_k127_3342147_31 Protein of unknown function (DUF3035) - - - 0.000000000000000000001027 103.0
SHD3_k127_3342147_32 - - - - 0.000000000000000002275 95.0
SHD3_k127_3342147_33 Belongs to the ompA family - - - 0.00000000000000003327 93.0
SHD3_k127_3342147_34 PilZ domain - - - 0.0000000005509 65.0
SHD3_k127_3342147_35 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20940 - 1.14.13.218 0.00000001018 59.0
SHD3_k127_3342147_36 Protein of unknown function (DUF3096) - - - 0.00000001305 59.0
SHD3_k127_3342147_4 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 9.752e-215 669.0
SHD3_k127_3342147_5 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 600.0
SHD3_k127_3342147_6 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 570.0
SHD3_k127_3342147_7 Long-chain fatty aldehyde decarbonylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 559.0
SHD3_k127_3342147_8 cytochrome c biogenesis protein K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 555.0
SHD3_k127_3342147_9 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 422.0
SHD3_k127_3456543_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 299.0
SHD3_k127_3456543_1 Thioesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005877 261.0
SHD3_k127_3456543_2 Dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000001852 179.0
SHD3_k127_3456543_3 arsenate reductase K00537 - 1.20.4.1 0.00000000000000000000000000000000000000005329 154.0
SHD3_k127_3456543_4 Sel1-like repeats. K07126,K13582 - - 0.00000000000000000000000000000000002666 154.0
SHD3_k127_3456543_5 alpha beta - - - 0.0000000000003743 73.0
SHD3_k127_3456543_6 PAS domain - - - 0.0006281 49.0
SHD3_k127_3460158_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 9.449e-220 690.0
SHD3_k127_3460158_1 Aminotransferase class-III K12256 - 2.6.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 578.0
SHD3_k127_3460158_10 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000005151 215.0
SHD3_k127_3460158_11 Thioesterase - - - 0.0000000000000000000000000000000000000000000000000000000000007826 213.0
SHD3_k127_3460158_12 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000001129 210.0
SHD3_k127_3460158_13 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000002839 209.0
SHD3_k127_3460158_14 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000008059 202.0
SHD3_k127_3460158_15 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000001416 165.0
SHD3_k127_3460158_16 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000003305 162.0
SHD3_k127_3460158_17 - - - - 0.00000000000000000000000000000000000000003885 154.0
SHD3_k127_3460158_18 transcriptional regulator - - - 0.0000000000000000000000000000000000000002418 151.0
SHD3_k127_3460158_19 NADP transhydrogenase K00324 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 0.0000000000000000000000000000000000000004609 151.0
SHD3_k127_3460158_2 Sigma-54 interaction domain - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 507.0
SHD3_k127_3460158_20 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000001685 146.0
SHD3_k127_3460158_21 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000003803 139.0
SHD3_k127_3460158_22 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000005498 130.0
SHD3_k127_3460158_23 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000003079 133.0
SHD3_k127_3460158_24 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000335 115.0
SHD3_k127_3460158_25 YCII-related domain K09780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000001336 100.0
SHD3_k127_3460158_26 COG2365 Protein tyrosine serine phosphatase - - - 0.0000000000000000005708 96.0
SHD3_k127_3460158_3 transhydrogenase subunit alpha K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 501.0
SHD3_k127_3460158_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 482.0
SHD3_k127_3460158_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 470.0
SHD3_k127_3460158_6 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 337.0
SHD3_k127_3460158_7 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 301.0
SHD3_k127_3460158_8 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.000000000000000000000000000000000000000000000000000000000000000000000000001791 260.0
SHD3_k127_3460158_9 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.0000000000000000000000000000000000000000000000000000000000004489 223.0
SHD3_k127_3517058_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 595.0
SHD3_k127_3517058_1 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 543.0
SHD3_k127_3517058_2 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 450.0
SHD3_k127_3517058_3 ISXO2-like transposase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 389.0
SHD3_k127_3517058_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000008258 156.0
SHD3_k127_3517058_5 Regulator - - - 0.0000000000000000000000000000000001297 136.0
SHD3_k127_3517058_6 - - - - 0.000000002553 64.0
SHD3_k127_3661161_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 382.0
SHD3_k127_3661161_1 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 374.0
SHD3_k127_3661161_10 cheY-homologous receiver domain K13589 - - 0.000000000000000000000000000000000000000000003145 167.0
SHD3_k127_3661161_11 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000007391 163.0
SHD3_k127_3661161_12 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000002949 148.0
SHD3_k127_3661161_13 Autotransporter beta-domain - - - 0.00000000000000000000000000000000000047 163.0
SHD3_k127_3661161_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000002539 152.0
SHD3_k127_3661161_15 GtrA-like protein - - - 0.0000000000000000001289 101.0
SHD3_k127_3661161_16 TIGRFAM TonB family protein K03832 - - 0.000000000000003702 83.0
SHD3_k127_3661161_17 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000001434 67.0
SHD3_k127_3661161_18 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.0009593 44.0
SHD3_k127_3661161_2 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 362.0
SHD3_k127_3661161_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 345.0
SHD3_k127_3661161_4 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 333.0
SHD3_k127_3661161_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 311.0
SHD3_k127_3661161_6 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 294.0
SHD3_k127_3661161_7 Binding-protein-dependent transport system inner membrane component K02018 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 284.0
SHD3_k127_3661161_8 Glyoxalase bleomycin resistance protein dioxygenase K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000009323 244.0
SHD3_k127_3661161_9 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbD K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002102 248.0
SHD3_k127_3687812_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1017.0
SHD3_k127_3687812_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.239e-262 814.0
SHD3_k127_3687812_10 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 316.0
SHD3_k127_3687812_11 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 303.0
SHD3_k127_3687812_12 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003006 267.0
SHD3_k127_3687812_13 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000004124 274.0
SHD3_k127_3687812_14 transporter K07238,K11021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006279 265.0
SHD3_k127_3687812_15 Dienelactone hydrolase family K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006058 252.0
SHD3_k127_3687812_16 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000001212 199.0
SHD3_k127_3687812_17 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000005754 188.0
SHD3_k127_3687812_18 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000007747 175.0
SHD3_k127_3687812_19 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000001307 174.0
SHD3_k127_3687812_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 8.228e-238 743.0
SHD3_k127_3687812_20 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000000000483 165.0
SHD3_k127_3687812_21 Protein of unknown function (DUF992) - - - 0.000000000000000000000000000000000000004139 153.0
SHD3_k127_3687812_22 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000001384 144.0
SHD3_k127_3687812_23 Protein required for attachment to host cells - - - 0.0000000000000000000000000000000008978 136.0
SHD3_k127_3687812_24 Uncharacterized conserved protein (DUF2267) - - - 0.00000000000000000000000000003126 129.0
SHD3_k127_3687812_25 PFAM Transglycosylase-associated protein - - - 0.000000000000000000000000003458 115.0
SHD3_k127_3687812_26 Colicin V production protein K03558 - - 0.000000000000000000000005416 109.0
SHD3_k127_3687812_27 ChaB K06197 - - 0.000000000000000000007624 93.0
SHD3_k127_3687812_28 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.0000000000000002662 86.0
SHD3_k127_3687812_29 PAS domain - - - 0.00000000131 65.0
SHD3_k127_3687812_3 DNA polymerase X family K02347 - - 7.142e-209 664.0
SHD3_k127_3687812_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 571.0
SHD3_k127_3687812_5 Glutamine amidotransferase domain K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 552.0
SHD3_k127_3687812_6 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 506.0
SHD3_k127_3687812_7 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 390.0
SHD3_k127_3687812_8 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 357.0
SHD3_k127_3687812_9 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 332.0
SHD3_k127_3715329_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 2.794e-298 920.0
SHD3_k127_3715329_1 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 3.368e-234 732.0
SHD3_k127_3715329_10 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000004961 274.0
SHD3_k127_3715329_11 Nucleotidyltransferase K09962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000625 243.0
SHD3_k127_3715329_12 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000003447 215.0
SHD3_k127_3715329_13 SURF1 family K14998 - - 0.0000000000000000000000000000000000000000000000002049 184.0
SHD3_k127_3715329_14 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000002161 183.0
SHD3_k127_3715329_15 Threonine synthase K01733 GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000001107 164.0
SHD3_k127_3715329_16 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000002063 135.0
SHD3_k127_3715329_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000011 111.0
SHD3_k127_3715329_18 Protein of unknown function (DUF952) - - - 0.00000000000000000000000003365 120.0
SHD3_k127_3715329_19 Activator of Hsp90 ATPase homolog 1-like - - - 0.000000000000003651 87.0
SHD3_k127_3715329_2 Glutamate-cysteine ligase family 2(GCS2) K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 592.0
SHD3_k127_3715329_20 - - - - 0.00000000004611 67.0
SHD3_k127_3715329_21 - - - - 0.0000695 46.0
SHD3_k127_3715329_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 510.0
SHD3_k127_3715329_4 cytochrome c oxidase subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 393.0
SHD3_k127_3715329_5 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 343.0
SHD3_k127_3715329_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 343.0
SHD3_k127_3715329_7 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 335.0
SHD3_k127_3715329_8 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 328.0
SHD3_k127_3715329_9 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 317.0
SHD3_k127_3756007_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1534.0
SHD3_k127_3756007_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004549 272.0
SHD3_k127_3756007_2 Protein of unknown function (DUF992) - - - 0.00000000000000000000000000000000000001523 151.0
SHD3_k127_3756007_3 Glycine zipper 2TM domain - - - 0.000000000000000000000006149 109.0
SHD3_k127_3772749_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 492.0
SHD3_k127_3772749_1 PFAM Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008646 283.0
SHD3_k127_3772749_2 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000001441 216.0
SHD3_k127_3772749_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000006303 158.0
SHD3_k127_3772749_4 Acetyltransferase (GNAT) domain K03823 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 2.3.1.183 0.0000000000000000000000000000000000007646 142.0
SHD3_k127_3772772_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 615.0
SHD3_k127_3772772_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 486.0
SHD3_k127_3772772_2 NADP-dependent K00001,K07119 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 417.0
SHD3_k127_3772772_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 328.0
SHD3_k127_3772772_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000003357 176.0
SHD3_k127_3772772_5 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286,K08641 - 3.4.13.22,3.4.16.4 0.00000000000000000000000000000000000001094 148.0
SHD3_k127_3772772_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000003776 104.0
SHD3_k127_3824159_0 Type II/IV secretion system protein K02283 - - 4.957e-236 737.0
SHD3_k127_3824159_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 607.0
SHD3_k127_3824159_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 358.0
SHD3_k127_3824159_11 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 359.0
SHD3_k127_3824159_12 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 342.0
SHD3_k127_3824159_13 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 338.0
SHD3_k127_3824159_14 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 327.0
SHD3_k127_3824159_15 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 299.0
SHD3_k127_3824159_16 Protein conserved in bacteria K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 295.0
SHD3_k127_3824159_17 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 297.0
SHD3_k127_3824159_18 trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 288.0
SHD3_k127_3824159_19 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001191 282.0
SHD3_k127_3824159_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 579.0
SHD3_k127_3824159_20 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006648 274.0
SHD3_k127_3824159_21 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003578 279.0
SHD3_k127_3824159_22 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002509 271.0
SHD3_k127_3824159_23 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002683 244.0
SHD3_k127_3824159_24 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000003121 236.0
SHD3_k127_3824159_25 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000006563 241.0
SHD3_k127_3824159_26 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000009125 229.0
SHD3_k127_3824159_27 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004086 228.0
SHD3_k127_3824159_28 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000001101 216.0
SHD3_k127_3824159_29 PFAM cytochrome c class I K08738 - - 0.0000000000000000000000000000000000000000000000000001571 194.0
SHD3_k127_3824159_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 571.0
SHD3_k127_3824159_30 Protein of unknown function (DUF1036) - - - 0.0000000000000000000000000000000000000000000000001638 190.0
SHD3_k127_3824159_31 Hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000019 184.0
SHD3_k127_3824159_32 Pilus assembly protein CpaE K02282 - - 0.000000000000000000000000000000000000000000001159 168.0
SHD3_k127_3824159_33 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000002088 115.0
SHD3_k127_3824159_34 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000003951 105.0
SHD3_k127_3824159_35 COG0457 FOG TPR repeat - - - 0.0000000000000000001082 102.0
SHD3_k127_3824159_36 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000526 64.0
SHD3_k127_3824159_37 Protein of unknown function (DUF805) - - - 0.0002229 48.0
SHD3_k127_3824159_38 Protein of unknown function (DUF805) - - - 0.0006689 46.0
SHD3_k127_3824159_4 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 499.0
SHD3_k127_3824159_5 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 484.0
SHD3_k127_3824159_6 PFAM transferase hexapeptide repeat containing protein K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 409.0
SHD3_k127_3824159_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 380.0
SHD3_k127_3824159_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 380.0
SHD3_k127_3824159_9 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 367.0
SHD3_k127_3968577_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 513.0
SHD3_k127_3968577_1 MlaC protein K07323 - - 0.00000000000000000000000004175 116.0
SHD3_k127_3968577_2 - - - - 0.00000000000000000000002853 112.0
SHD3_k127_3968577_3 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000001076 83.0
SHD3_k127_3968577_4 Terminase RNaseH-like domain - - - 0.0000000007258 65.0
SHD3_k127_3968577_5 TadE-like protein - - - 0.000001054 56.0
SHD3_k127_3968577_6 TadE-like protein - - - 0.0001404 53.0
SHD3_k127_3985251_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 470.0
SHD3_k127_3985251_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 450.0
SHD3_k127_3985251_10 Flagellar hook protein flgE K02390 - - 0.0000000000001293 75.0
SHD3_k127_3985251_11 Peptidase family M48 - - - 0.00000000001141 78.0
SHD3_k127_3985251_12 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000006821 57.0
SHD3_k127_3985251_13 TIGRFAM Flagellar hook-associated protein 3 K02397 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000008301 60.0
SHD3_k127_3985251_14 YjbR - - - 0.0000184 51.0
SHD3_k127_3985251_2 Belongs to the flagella basal body rod proteins family K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 430.0
SHD3_k127_3985251_3 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000001827 173.0
SHD3_k127_3985251_4 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000004714 138.0
SHD3_k127_3985251_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K04786,K04791,K10714,K12440,K12441,K15320,K15395,K15641,K16128,K16396,K16417 - 2.3.1.165 0.00000000000000000000000000000001074 133.0
SHD3_k127_3985251_6 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000003397 129.0
SHD3_k127_3985251_7 Transmembrane sensor domain - - - 0.00000000000000000000001887 115.0
SHD3_k127_3985251_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000004437 100.0
SHD3_k127_3985251_9 Flagellar hook-length control protein FliK K10565 - - 0.000000000000000000001012 110.0
SHD3_k127_3993521_0 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 407.0
SHD3_k127_3993521_1 Prolyl oligopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001165 285.0
SHD3_k127_3993521_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002276 271.0
SHD3_k127_3993521_4 Peptidase S9 prolyl oligopeptidase active site - - - 0.000000000003227 79.0
SHD3_k127_3993521_5 - - - - 0.0002502 51.0
SHD3_k127_4001138_0 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 563.0
SHD3_k127_4001138_1 Methionine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 518.0
SHD3_k127_4001138_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 414.0
SHD3_k127_4001138_3 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 395.0
SHD3_k127_4001138_4 Citrate synthase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009703 338.0
SHD3_k127_4001138_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001642 279.0
SHD3_k127_4001138_6 integrase family - - - 0.000000000000000000000007341 103.0
SHD3_k127_4020521_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 7.545e-249 777.0
SHD3_k127_4020521_1 EamA-like transporter family K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000178 252.0
SHD3_k127_4020521_2 tRNA synthetases class I (C) catalytic domain K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000001653 183.0
SHD3_k127_4043595_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 2.625e-201 636.0
SHD3_k127_4043595_1 tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 501.0
SHD3_k127_4043595_10 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000000000001377 172.0
SHD3_k127_4043595_11 Integral membrane protein (intg_mem_TP0381) - - - 0.000000000000000000000000000000000000003708 155.0
SHD3_k127_4043595_12 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000000002565 109.0
SHD3_k127_4043595_13 Protein of unknown function (DUF2842) - - - 0.000000003662 60.0
SHD3_k127_4043595_2 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 450.0
SHD3_k127_4043595_3 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 444.0
SHD3_k127_4043595_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 383.0
SHD3_k127_4043595_5 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 381.0
SHD3_k127_4043595_6 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 347.0
SHD3_k127_4043595_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 320.0
SHD3_k127_4043595_8 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007184 229.0
SHD3_k127_4043595_9 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000003874 199.0
SHD3_k127_4049460_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 1673.0
SHD3_k127_4049460_1 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 615.0
SHD3_k127_4049460_2 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 525.0
SHD3_k127_4049460_3 Phosphofructokinase K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 517.0
SHD3_k127_4049460_4 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 308.0
SHD3_k127_4049460_5 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000001187 259.0
SHD3_k127_4049460_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000003616 190.0
SHD3_k127_4049460_7 Haem-degrading - - - 0.00000000000001635 82.0
SHD3_k127_4049460_8 - - - - 0.00000000000003001 78.0
SHD3_k127_4049460_9 Belongs to the ompA family - - - 0.00003012 50.0
SHD3_k127_4052717_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 4.782e-209 660.0
SHD3_k127_4052717_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 314.0
SHD3_k127_4052717_2 NnrS protein K07234 - - 0.000000000000000000002944 94.0
SHD3_k127_4055450_0 amine dehydrogenase activity - - - 7.586e-276 876.0
SHD3_k127_4055450_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 605.0
SHD3_k127_4055450_10 Transcriptional regulator K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000006737 104.0
SHD3_k127_4055450_2 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 491.0
SHD3_k127_4055450_3 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 441.0
SHD3_k127_4055450_4 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 426.0
SHD3_k127_4055450_5 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 362.0
SHD3_k127_4055450_6 Enoyl-CoA hydratase isomerase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 344.0
SHD3_k127_4055450_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 293.0
SHD3_k127_4055450_8 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002728 271.0
SHD3_k127_4055450_9 Protein of unknown function (DUF1134) - - - 0.00000000000000000000000000000000000000000000000000000000001629 211.0
SHD3_k127_4063215_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.035e-238 765.0
SHD3_k127_4063215_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.48e-229 724.0
SHD3_k127_4063215_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 445.0
SHD3_k127_4063215_11 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 396.0
SHD3_k127_4063215_12 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 376.0
SHD3_k127_4063215_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 364.0
SHD3_k127_4063215_14 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 325.0
SHD3_k127_4063215_15 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 313.0
SHD3_k127_4063215_16 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004845 245.0
SHD3_k127_4063215_17 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000007996 249.0
SHD3_k127_4063215_18 FAD dependent oxidoreductase K00285,K03153 - 1.4.3.19,1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000003455 241.0
SHD3_k127_4063215_19 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351 - - 0.000000000000000000000000000000000000000000000000000000000000000004451 239.0
SHD3_k127_4063215_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 5.675e-209 658.0
SHD3_k127_4063215_20 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000002471 222.0
SHD3_k127_4063215_21 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000009666 224.0
SHD3_k127_4063215_22 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000000000000007199 209.0
SHD3_k127_4063215_23 Lytic transglycosylase - - - 0.000000000000000000000000000000000000000000000000001897 197.0
SHD3_k127_4063215_24 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000007575 188.0
SHD3_k127_4063215_25 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000002256 177.0
SHD3_k127_4063215_26 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000008154 172.0
SHD3_k127_4063215_27 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.0000000000000000000000000000000000000003682 153.0
SHD3_k127_4063215_28 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000006172 152.0
SHD3_k127_4063215_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 2.11e-196 621.0
SHD3_k127_4063215_30 MAPEG family - - - 0.000000000000000000000000000006149 124.0
SHD3_k127_4063215_31 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000005978 126.0
SHD3_k127_4063215_32 Cupredoxin-like domain - - - 0.0000000000000000000000001996 111.0
SHD3_k127_4063215_33 COG0457 FOG TPR repeat - - - 0.000000000000000000000001953 111.0
SHD3_k127_4063215_34 - K20326 - - 0.000000000000000000000004758 114.0
SHD3_k127_4063215_35 PFAM Cytochrome P450 - - - 0.000000000000001969 86.0
SHD3_k127_4063215_36 Septum formation initiator - - - 0.0000000000002225 74.0
SHD3_k127_4063215_37 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000003798 70.0
SHD3_k127_4063215_38 CDP-alcohol phosphatidyltransferase - - - 0.000000000009587 73.0
SHD3_k127_4063215_39 PAS domain - - - 0.0002382 50.0
SHD3_k127_4063215_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 9.109e-194 617.0
SHD3_k127_4063215_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 517.0
SHD3_k127_4063215_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 496.0
SHD3_k127_4063215_7 Glycosyl transferase family group 2 K20327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 494.0
SHD3_k127_4063215_8 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 457.0
SHD3_k127_4063215_9 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 464.0
SHD3_k127_4117013_0 Threonyl and Alanyl tRNA synthetase second additional domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1148.0
SHD3_k127_4117013_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1019.0
SHD3_k127_4117013_10 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 508.0
SHD3_k127_4117013_11 His Kinase A (phosphoacceptor) domain K13587 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 518.0
SHD3_k127_4117013_12 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 453.0
SHD3_k127_4117013_13 Major facilitator Superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 439.0
SHD3_k127_4117013_14 GtrA-like protein K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 430.0
SHD3_k127_4117013_15 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 420.0
SHD3_k127_4117013_16 nitrite reductase [NAD(P)H] activity K15762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 430.0
SHD3_k127_4117013_17 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 416.0
SHD3_k127_4117013_18 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 417.0
SHD3_k127_4117013_19 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 404.0
SHD3_k127_4117013_2 Penicillin amidase K01434,K07116 - 3.5.1.11,3.5.1.97 5.337e-299 933.0
SHD3_k127_4117013_20 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 400.0
SHD3_k127_4117013_21 Phytanoyl-CoA dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 377.0
SHD3_k127_4117013_22 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 351.0
SHD3_k127_4117013_23 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 360.0
SHD3_k127_4117013_24 Catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide K03119 GO:0000907,GO:0000908,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0044237,GO:0044248,GO:0044273,GO:0044424,GO:0044464,GO:0051213,GO:0055114 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 340.0
SHD3_k127_4117013_25 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 330.0
SHD3_k127_4117013_26 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 318.0
SHD3_k127_4117013_27 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 323.0
SHD3_k127_4117013_28 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 312.0
SHD3_k127_4117013_29 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 306.0
SHD3_k127_4117013_3 peptidase K07386 - - 5.427e-268 842.0
SHD3_k127_4117013_30 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 302.0
SHD3_k127_4117013_31 abc transporter atp-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 307.0
SHD3_k127_4117013_32 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 301.0
SHD3_k127_4117013_33 Ion channel K10716 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 312.0
SHD3_k127_4117013_34 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 292.0
SHD3_k127_4117013_35 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008614 282.0
SHD3_k127_4117013_36 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003667 285.0
SHD3_k127_4117013_37 Transmembrane protein 43 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008634 281.0
SHD3_k127_4117013_38 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000001074 266.0
SHD3_k127_4117013_39 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000003215 264.0
SHD3_k127_4117013_4 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 2.471e-241 749.0
SHD3_k127_4117013_40 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001767 254.0
SHD3_k127_4117013_41 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000002371 255.0
SHD3_k127_4117013_42 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004354 251.0
SHD3_k127_4117013_43 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000001994 237.0
SHD3_k127_4117013_44 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000156 236.0
SHD3_k127_4117013_45 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000001011 231.0
SHD3_k127_4117013_46 Bacterial export proteins, family 1 K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000009761 227.0
SHD3_k127_4117013_47 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000009766 218.0
SHD3_k127_4117013_48 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001009 204.0
SHD3_k127_4117013_49 Flagellar basal body rod FlgEFG protein C-terminal K02388 - - 0.00000000000000000000000000000000000000000000000003041 181.0
SHD3_k127_4117013_5 PQQ-like domain K00117 - 1.1.5.2 5.337e-218 695.0
SHD3_k127_4117013_50 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.0000000000000000000000000000000000000000000000002423 198.0
SHD3_k127_4117013_52 COQ9 K18587 - - 0.000000000000000000000000000000000000000000002613 172.0
SHD3_k127_4117013_53 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000004209 183.0
SHD3_k127_4117013_54 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000004473 163.0
SHD3_k127_4117013_55 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000006012 167.0
SHD3_k127_4117013_56 PFAM Cupin 2 conserved barrel domain protein K05913 - 1.13.11.41 0.0000000000000000000000000000000000000000001433 163.0
SHD3_k127_4117013_57 - - - - 0.000000000000000000000000000000000000000001893 162.0
SHD3_k127_4117013_58 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000004554 147.0
SHD3_k127_4117013_59 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000199 149.0
SHD3_k127_4117013_6 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 4.168e-208 654.0
SHD3_k127_4117013_60 transcriptional regulators K03892 - - 0.00000000000000000000000000000001001 130.0
SHD3_k127_4117013_61 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000004787 135.0
SHD3_k127_4117013_62 Domain of unknown function (DUF1476) - - - 0.0000000000000000000000000000005087 124.0
SHD3_k127_4117013_63 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000001885 120.0
SHD3_k127_4117013_64 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000007977 115.0
SHD3_k127_4117013_65 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000446 108.0
SHD3_k127_4117013_66 PQ loop repeat K15383 - - 0.0000000000000000000000000702 109.0
SHD3_k127_4117013_67 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000131 102.0
SHD3_k127_4117013_68 lactoylglutathione lyase activity - - - 0.0000000000000000000009765 102.0
SHD3_k127_4117013_69 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000001388 106.0
SHD3_k127_4117013_7 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 612.0
SHD3_k127_4117013_70 Acetyltransferase (GNAT) domain - - - 0.000000000000000000009735 98.0
SHD3_k127_4117013_71 Flagellar biosynthesis K02420 - - 0.00000000000000000004174 92.0
SHD3_k127_4117013_72 Flavin containing amine oxidoreductase K06954 - - 0.0000000000000000002113 89.0
SHD3_k127_4117013_73 - - - - 0.0000000000000000003791 90.0
SHD3_k127_4117013_74 Glycosyl transferase, family 2 - - - 0.000000000000003704 87.0
SHD3_k127_4117013_75 Protein of unknown function (DUF465) - - - 0.00000000000001023 79.0
SHD3_k127_4117013_76 Flagellar biosynthesis protein, FliO K02418 - - 0.00000000000006026 75.0
SHD3_k127_4117013_77 Flagellar hook-basal body K02408 - - 0.0000000000005289 72.0
SHD3_k127_4117013_79 small protein - - - 0.0000000405 56.0
SHD3_k127_4117013_8 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 569.0
SHD3_k127_4117013_81 - - - - 0.0000002118 59.0
SHD3_k127_4117013_82 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000607 58.0
SHD3_k127_4117013_83 Bacterial protein of unknown function (DUF883) - - - 0.0000105 52.0
SHD3_k127_4117013_9 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 541.0
SHD3_k127_4224568_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 504.0
SHD3_k127_4224568_1 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000316 213.0
SHD3_k127_4224568_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000001925 174.0
SHD3_k127_4224568_3 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000002818 160.0
SHD3_k127_4224568_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0008996 43.0
SHD3_k127_4229474_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1369.0
SHD3_k127_4229474_1 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1260.0
SHD3_k127_4229474_10 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000751 475.0
SHD3_k127_4229474_11 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 468.0
SHD3_k127_4229474_12 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 469.0
SHD3_k127_4229474_13 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 468.0
SHD3_k127_4229474_14 D-ala D-ala ligase N-terminus K00075,K01921 - 1.3.1.98,6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 426.0
SHD3_k127_4229474_15 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 415.0
SHD3_k127_4229474_16 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 405.0
SHD3_k127_4229474_17 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 373.0
SHD3_k127_4229474_18 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 353.0
SHD3_k127_4229474_19 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 344.0
SHD3_k127_4229474_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1057.0
SHD3_k127_4229474_20 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 331.0
SHD3_k127_4229474_21 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 319.0
SHD3_k127_4229474_22 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 310.0
SHD3_k127_4229474_23 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004273 270.0
SHD3_k127_4229474_24 Tellurite resistance protein TerB K05801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009284 274.0
SHD3_k127_4229474_25 COG3023 Negative regulator of beta-lactamase expression K01447 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000002258 263.0
SHD3_k127_4229474_26 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000002776 256.0
SHD3_k127_4229474_27 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000001705 238.0
SHD3_k127_4229474_28 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000000008692 224.0
SHD3_k127_4229474_29 Siderophore-interacting protein - - - 0.000000000000000000000000000000000000000000000000000000000000003047 228.0
SHD3_k127_4229474_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.187e-267 843.0
SHD3_k127_4229474_30 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000000000000000000000000000000004432 198.0
SHD3_k127_4229474_31 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000003836 203.0
SHD3_k127_4229474_32 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000001475 202.0
SHD3_k127_4229474_33 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890,K04566,K06878 - 6.1.1.10,6.1.1.20,6.1.1.6 0.0000000000000000000000000000000000000000000000006334 176.0
SHD3_k127_4229474_34 - - - - 0.000000000000000000000000000000000000000000000000679 177.0
SHD3_k127_4229474_35 Cell division protein FtsQ K03589 - - 0.0000000000000000000000000000000000000000001626 172.0
SHD3_k127_4229474_36 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000001786 140.0
SHD3_k127_4229474_37 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000003918 116.0
SHD3_k127_4229474_38 Ribbon-helix-helix protein, copG family - - - 0.0000000000000000000000508 104.0
SHD3_k127_4229474_39 - - - - 0.000000000000000000002146 97.0
SHD3_k127_4229474_4 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 6.808e-251 789.0
SHD3_k127_4229474_41 secreted (periplasmic) protein - - - 0.000001405 55.0
SHD3_k127_4229474_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 614.0
SHD3_k127_4229474_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 535.0
SHD3_k127_4229474_7 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 534.0
SHD3_k127_4229474_8 PFAM Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 516.0
SHD3_k127_4229474_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 497.0
SHD3_k127_4248341_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 3.057e-309 958.0
SHD3_k127_4248341_1 MMPL family K07003 - - 6.904e-268 850.0
SHD3_k127_4248341_10 hopanoid biosynthesis associated membrane protein HpnM K07323 - - 0.0000000000000000000000000000000000000000001708 168.0
SHD3_k127_4248341_11 PFAM purine or other phosphorylase family 1 - - - 0.000000000000000000000000000000000004501 148.0
SHD3_k127_4248341_12 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000009536 121.0
SHD3_k127_4248341_13 Phytoene synthase K21678 - 2.5.1.103 0.000000000000002014 77.0
SHD3_k127_4248341_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.041e-266 833.0
SHD3_k127_4248341_3 Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 601.0
SHD3_k127_4248341_4 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 559.0
SHD3_k127_4248341_5 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 520.0
SHD3_k127_4248341_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 466.0
SHD3_k127_4248341_7 Amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 318.0
SHD3_k127_4248341_8 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 305.0
SHD3_k127_4248341_9 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001032 220.0
SHD3_k127_4292807_0 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 524.0
SHD3_k127_4292807_1 Belongs to the arylamine N-acetyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003676 252.0
SHD3_k127_4292807_2 Putative sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004176 254.0
SHD3_k127_4292807_3 PadR family transcriptional regulator K10947 - - 0.000000000000000000000000000000003 133.0
SHD3_k127_4292807_4 Peptidase family M23 - - - 0.000000000000000013 93.0
SHD3_k127_4292807_5 - - - - 0.000006902 57.0
SHD3_k127_4327450_0 PFAM luciferase family protein - - - 5.339e-210 658.0
SHD3_k127_4327450_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 476.0
SHD3_k127_4327450_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 430.0
SHD3_k127_4327450_3 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 333.0
SHD3_k127_4327450_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000002921 218.0
SHD3_k127_4330368_0 AMP-binding enzyme C-terminal domain - - - 1.776e-223 703.0
SHD3_k127_4330368_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 535.0
SHD3_k127_4330368_10 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000002694 145.0
SHD3_k127_4330368_11 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000001906 128.0
SHD3_k127_4330368_12 PAS domain - - - 0.0000000000000002741 86.0
SHD3_k127_4330368_13 Zinc-dependent metalloprotease - - - 0.0000001969 61.0
SHD3_k127_4330368_14 - - - - 0.00001538 55.0
SHD3_k127_4330368_2 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 525.0
SHD3_k127_4330368_3 Alkane 1-monooxygenase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 522.0
SHD3_k127_4330368_4 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 440.0
SHD3_k127_4330368_5 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 402.0
SHD3_k127_4330368_6 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 376.0
SHD3_k127_4330368_7 Histidine kinase-like ATPases K14980 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 368.0
SHD3_k127_4330368_8 Transcriptional regulatory protein, C terminal K14981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 291.0
SHD3_k127_4330368_9 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000000000000000000000000000252 180.0
SHD3_k127_4341884_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.964e-284 877.0
SHD3_k127_4341884_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 297.0
SHD3_k127_4341884_2 IS66 Orf2 like protein K07484 - - 0.000000000000000000000000000000000000000000000000000000000000003638 219.0
SHD3_k127_4341884_3 Transposase K07483 - - 0.000000000000000000000000000000000007251 137.0
SHD3_k127_4341884_4 Sodium Bile acid symporter family - - - 0.00000000000000000000000000000003666 137.0
SHD3_k127_4348537_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 528.0
SHD3_k127_4348537_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 354.0
SHD3_k127_4348537_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007274 261.0
SHD3_k127_445641_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 1.099e-202 653.0
SHD3_k127_445641_1 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 419.0
SHD3_k127_445641_11 YnbE-like lipoprotein - - - 0.000000000000000005968 85.0
SHD3_k127_445641_12 Flp/Fap pilin component K02651 - - 0.000000000002485 68.0
SHD3_k127_445641_2 Dicarboxylate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 362.0
SHD3_k127_445641_3 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000006151 268.0
SHD3_k127_445641_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000002698 240.0
SHD3_k127_445641_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000002458 181.0
SHD3_k127_445641_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000002525 180.0
SHD3_k127_445641_7 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.000000000000000000000000000000000000000002148 160.0
SHD3_k127_445641_8 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000001488 139.0
SHD3_k127_445641_9 Protein of unknown function (DUF1318) K09978 - - 0.00000000000000000000000001681 115.0
SHD3_k127_4521066_0 Serine carboxypeptidase - - - 8.939e-219 691.0
SHD3_k127_4521066_1 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 582.0
SHD3_k127_4521066_10 Haem-binding domain - - - 0.000000000000000000000000422 113.0
SHD3_k127_4521066_11 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000009293 102.0
SHD3_k127_4521066_12 PAS domain - - - 0.000000000005092 72.0
SHD3_k127_4521066_13 PFAM Flp Fap pilin component K02651 - - 0.0000000003406 62.0
SHD3_k127_4521066_14 CAAX protease self-immunity K07052 - - 0.000007242 57.0
SHD3_k127_4521066_15 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0001155 49.0
SHD3_k127_4521066_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 453.0
SHD3_k127_4521066_3 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 335.0
SHD3_k127_4521066_4 DoxX - - - 0.000000000000000000000000000000000000000000000000000001119 197.0
SHD3_k127_4521066_5 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000239 174.0
SHD3_k127_4521066_6 - - - - 0.0000000000000000000000000000000000000000000005215 181.0
SHD3_k127_4521066_7 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000008586 165.0
SHD3_k127_4521066_8 acetyltransferase - - - 0.000000000000000000000000000000000000000006138 160.0
SHD3_k127_4521066_9 - - - - 0.0000000000000000000000000000001549 127.0
SHD3_k127_4553658_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2148.0
SHD3_k127_4553658_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2075.0
SHD3_k127_4553658_2 Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000008632 221.0
SHD3_k127_4553658_3 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000001294 216.0
SHD3_k127_4553658_4 MAPEG family - - - 0.00000000000000000000000000000000000000000000005285 174.0
SHD3_k127_4553658_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000003648 116.0
SHD3_k127_4553658_6 nUDIX hydrolase K01518,K08296 - 3.6.1.17 0.0000000001623 62.0
SHD3_k127_4580108_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 1.294e-246 783.0
SHD3_k127_4580108_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 587.0
SHD3_k127_4580108_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 569.0
SHD3_k127_4580108_3 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 334.0
SHD3_k127_4580108_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 327.0
SHD3_k127_4580108_5 protein conserved in bacteria K15539 - - 0.0000000000000000000000000000000000000000000008615 178.0
SHD3_k127_4580108_6 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000001099 151.0
SHD3_k127_4580108_7 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000001427 140.0
SHD3_k127_4580216_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1105.0
SHD3_k127_4580216_1 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 3.772e-279 871.0
SHD3_k127_4580216_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 398.0
SHD3_k127_4580216_11 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 374.0
SHD3_k127_4580216_12 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 351.0
SHD3_k127_4580216_13 COG0708 Exonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 338.0
SHD3_k127_4580216_14 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 333.0
SHD3_k127_4580216_15 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 337.0
SHD3_k127_4580216_16 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 320.0
SHD3_k127_4580216_17 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 312.0
SHD3_k127_4580216_18 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 304.0
SHD3_k127_4580216_19 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 300.0
SHD3_k127_4580216_2 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 5.302e-232 729.0
SHD3_k127_4580216_20 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 291.0
SHD3_k127_4580216_21 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001218 284.0
SHD3_k127_4580216_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003295 275.0
SHD3_k127_4580216_23 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000001218 273.0
SHD3_k127_4580216_24 PFAM Scaffold protein Nfu NifU N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002882 263.0
SHD3_k127_4580216_25 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005707 261.0
SHD3_k127_4580216_26 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003175 257.0
SHD3_k127_4580216_27 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.000000000000000000000000000000000000000000000000000000000000000003716 234.0
SHD3_k127_4580216_28 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000001231 230.0
SHD3_k127_4580216_29 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000333 215.0
SHD3_k127_4580216_3 reductase K00001,K14446 - 1.1.1.1,1.3.1.85 1.459e-194 609.0
SHD3_k127_4580216_30 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000001412 212.0
SHD3_k127_4580216_31 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06991 - - 0.000000000000000000000000000000000000000000000000000000000364 207.0
SHD3_k127_4580216_32 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000002828 198.0
SHD3_k127_4580216_33 Flagellar protein FlbT K06601 - - 0.0000000000000000000000000000000000000000000000009812 178.0
SHD3_k127_4580216_34 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000003108 176.0
SHD3_k127_4580216_35 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000002934 172.0
SHD3_k127_4580216_36 Alcohol dehydrogenase GroES-like domain K00001,K14446 - 1.1.1.1,1.3.1.85 0.00000000000000000000000000000000000000000000472 164.0
SHD3_k127_4580216_37 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000001705 159.0
SHD3_k127_4580216_38 Domain of unknown function (DUF3576) - - - 0.000000000000000000000000000000000000000512 153.0
SHD3_k127_4580216_39 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000158 150.0
SHD3_k127_4580216_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 595.0
SHD3_k127_4580216_40 PFAM peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000004709 150.0
SHD3_k127_4580216_41 PFAM CHAD domain containing protein - - - 0.000000000000000000000000000000001145 142.0
SHD3_k127_4580216_42 protein, possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000003428 130.0
SHD3_k127_4580216_43 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000006986 130.0
SHD3_k127_4580216_44 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000002268 128.0
SHD3_k127_4580216_45 Disulfide bond formation protein - - - 0.0000000000000000000000000000002968 130.0
SHD3_k127_4580216_46 - - - - 0.0000000000000000000000000002346 119.0
SHD3_k127_4580216_47 Flagellar protein FlaF K06602 - - 0.0000000000000000000000000008767 115.0
SHD3_k127_4580216_48 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.0000000000000000000000001427 112.0
SHD3_k127_4580216_49 FR47-like protein - - - 0.00000000000000000000001712 112.0
SHD3_k127_4580216_5 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 574.0
SHD3_k127_4580216_50 Thiamine monophosphate synthase - - - 0.0000000000000000000003102 104.0
SHD3_k127_4580216_51 - - - - 0.0000000000000000001667 99.0
SHD3_k127_4580216_52 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000114 94.0
SHD3_k127_4580216_53 - - - - 0.0000000000000006455 87.0
SHD3_k127_4580216_54 Gram-negative porin K08720 - - 0.000000000000001053 90.0
SHD3_k127_4580216_55 Lipopolysaccharide-assembly K03643 - - 0.000000000000007529 82.0
SHD3_k127_4580216_56 Protein involved in outer membrane biogenesis - - - 0.0000000000004858 81.0
SHD3_k127_4580216_57 Protein of unknown function (DUF1674) - - - 0.00000000001051 67.0
SHD3_k127_4580216_58 Chagasin family peptidase inhibitor I42 K14475 - - 0.0003197 48.0
SHD3_k127_4580216_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 416.0
SHD3_k127_4580216_7 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 417.0
SHD3_k127_4580216_8 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 415.0
SHD3_k127_4580216_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 393.0
SHD3_k127_4665235_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 6.594e-194 611.0
SHD3_k127_4665235_1 Belongs to the thiolase family K07823 - 2.3.1.174 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 586.0
SHD3_k127_4665235_10 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 372.0
SHD3_k127_4665235_11 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002361 258.0
SHD3_k127_4665235_12 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000003569 220.0
SHD3_k127_4665235_13 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000009565 213.0
SHD3_k127_4665235_14 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.0000000000000000000000000000000000000000000000000000001449 202.0
SHD3_k127_4665235_15 Autoinducer synthase K18096 - 2.3.1.228,2.3.1.229 0.000000000000000000000000000000000000000000002413 171.0
SHD3_k127_4665235_16 COG2771 DNA-binding HTH domain-containing proteins - - - 0.0000000000000000000000000000000000000009563 158.0
SHD3_k127_4665235_17 Cupin domain - - - 0.00000000000000000000000004901 114.0
SHD3_k127_4665235_18 amine oxidase K06954 - - 0.00000000000000000000003438 101.0
SHD3_k127_4665235_19 transcriptional regulator - - - 0.00000000000001141 83.0
SHD3_k127_4665235_2 Major facilitator Superfamily K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 569.0
SHD3_k127_4665235_3 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 552.0
SHD3_k127_4665235_4 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 549.0
SHD3_k127_4665235_5 isovaleryl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 503.0
SHD3_k127_4665235_6 Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 488.0
SHD3_k127_4665235_7 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 458.0
SHD3_k127_4665235_8 Chalcone and stilbene synthases, C-terminal domain K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 420.0
SHD3_k127_4665235_9 synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 389.0
SHD3_k127_4705742_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1047.0
SHD3_k127_4705742_1 MreB/Mbl protein K04043 - - 9.544e-314 970.0
SHD3_k127_4705742_10 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 355.0
SHD3_k127_4705742_11 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 353.0
SHD3_k127_4705742_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 329.0
SHD3_k127_4705742_13 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 315.0
SHD3_k127_4705742_14 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 309.0
SHD3_k127_4705742_15 Carbon-nitrogen hydrolase K01502 - 3.5.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004017 281.0
SHD3_k127_4705742_16 MFS_1 like family K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002306 269.0
SHD3_k127_4705742_17 ribosomal RNA adenine methylase transferase K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000004971 166.0
SHD3_k127_4705742_18 Universal stress protein family - - - 0.000000000000000000000000000000000000000001462 162.0
SHD3_k127_4705742_19 Acyltransferase family - - - 0.0000000000000000000000000000000000006889 153.0
SHD3_k127_4705742_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.582e-313 983.0
SHD3_k127_4705742_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000001961 116.0
SHD3_k127_4705742_21 - - - - 0.0000000000000001995 89.0
SHD3_k127_4705742_22 - - - - 0.0000000000002516 74.0
SHD3_k127_4705742_23 Hypoxia induced protein conserved region - - - 0.0000000003037 66.0
SHD3_k127_4705742_24 protein conserved in bacteria K09921 - - 0.000001261 59.0
SHD3_k127_4705742_3 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.038e-262 818.0
SHD3_k127_4705742_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.027e-262 826.0
SHD3_k127_4705742_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.878e-224 703.0
SHD3_k127_4705742_6 Peptidase dimerisation domain - - - 1.163e-213 672.0
SHD3_k127_4705742_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 510.0
SHD3_k127_4705742_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 485.0
SHD3_k127_4705742_9 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 406.0
SHD3_k127_4712165_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.753e-232 728.0
SHD3_k127_4712165_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001271 281.0
SHD3_k127_4712165_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003994 280.0
SHD3_k127_4712165_3 Peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000001311 235.0
SHD3_k127_4712165_4 - - - - 0.0000000000000000000000000000000000000000000000004171 179.0
SHD3_k127_4712165_5 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000001266 130.0
SHD3_k127_4712165_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000212 131.0
SHD3_k127_4712165_7 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000001139 57.0
SHD3_k127_4712165_8 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0008195 42.0
SHD3_k127_4712165_9 peptidyl-tyrosine sulfation - - - 0.0009133 46.0
SHD3_k127_4729595_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 588.0
SHD3_k127_4729595_1 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 463.0
SHD3_k127_4729595_10 - - - - 0.0004643 49.0
SHD3_k127_4729595_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 - 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 371.0
SHD3_k127_4729595_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003938 285.0
SHD3_k127_4729595_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004551 264.0
SHD3_k127_4729595_5 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000006433 211.0
SHD3_k127_4729595_6 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000004615 191.0
SHD3_k127_4729595_7 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000001548 186.0
SHD3_k127_4729595_8 Protein phosphatase 2C - - - 0.000000000000000000000000000000000003007 148.0
SHD3_k127_4729595_9 NUDIX domain - - - 0.00000000000000000000000000000000247 132.0
SHD3_k127_4732296_0 Transposase and inactivated derivatives - - - 1.055e-319 983.0
SHD3_k127_4732296_1 IstB-like ATP binding N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 513.0
SHD3_k127_4732296_2 Cytochrome c K19713 - 1.8.2.2 0.00000000000000000000002505 102.0
SHD3_k127_4739223_0 belongs to the aldehyde dehydrogenase family - - - 3.835e-252 782.0
SHD3_k127_4739223_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 5.566e-219 691.0
SHD3_k127_4739223_10 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 333.0
SHD3_k127_4739223_11 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 317.0
SHD3_k127_4739223_12 short-chain dehydrogenase K05296 - 1.1.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 315.0
SHD3_k127_4739223_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000002293 196.0
SHD3_k127_4739223_14 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000008407 151.0
SHD3_k127_4739223_15 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000001212 147.0
SHD3_k127_4739223_16 Alpha beta hydrolase - - - 0.0000000000000000000000000000000002671 142.0
SHD3_k127_4739223_17 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000002661 138.0
SHD3_k127_4739223_18 'PFAM Response regulator receiver - - - 0.0000000000000000000000404 106.0
SHD3_k127_4739223_19 Membrane - - - 0.0000000000000008313 87.0
SHD3_k127_4739223_2 Belongs to the thiolase family K00626 - 2.3.1.9 6.177e-211 665.0
SHD3_k127_4739223_22 PilZ domain - - - 0.0000000000159 68.0
SHD3_k127_4739223_23 - - - - 0.00000000002754 69.0
SHD3_k127_4739223_24 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000788 59.0
SHD3_k127_4739223_25 methyltransferase - - - 0.00000004684 57.0
SHD3_k127_4739223_26 - - - - 0.00000007274 57.0
SHD3_k127_4739223_3 - - - - 1.063e-202 634.0
SHD3_k127_4739223_4 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 585.0
SHD3_k127_4739223_5 Alcohol dehydrogenase GroES-like domain K00055 - 1.1.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 569.0
SHD3_k127_4739223_6 COG3552 Protein containing von Willebrand factor type A (vWA) domain K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 444.0
SHD3_k127_4739223_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 445.0
SHD3_k127_4739223_8 AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 438.0
SHD3_k127_4739223_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 411.0
SHD3_k127_4865192_0 acetyl-coa acetyltransferase K00626 - 2.3.1.9 2.615e-206 646.0
SHD3_k127_4865192_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 476.0
SHD3_k127_4865192_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 457.0
SHD3_k127_4865192_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000001563 189.0
SHD3_k127_4865192_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000001068 171.0
SHD3_k127_4865192_5 - - - - 0.00000000000000000000000000000000000000000001011 168.0
SHD3_k127_4865192_6 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000001377 166.0
SHD3_k127_4865192_7 RND efflux system, outer membrane lipoprotein - - - 0.00000000000000000000006367 102.0
SHD3_k127_4865192_8 Nodulation protein S (NodS) - - - 0.000000001291 61.0
SHD3_k127_4865192_9 Protein of unknown function (DUF1365) K09701 - - 0.0000002574 57.0
SHD3_k127_4868295_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.029e-290 908.0
SHD3_k127_4868295_1 glutamine synthetase K01915 - 6.3.1.2 9.584e-239 744.0
SHD3_k127_4868295_10 PFAM Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000184 267.0
SHD3_k127_4868295_11 signal transduction histidine kinase K07716 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000003216 256.0
SHD3_k127_4868295_12 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000000000000000000000000001499 201.0
SHD3_k127_4868295_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000004791 181.0
SHD3_k127_4868295_14 Aminoglycoside/hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.000000000000000000000000000000000002304 151.0
SHD3_k127_4868295_15 enoyl-CoA hydratase K15866 - 5.3.3.18 0.0003688 44.0
SHD3_k127_4868295_2 belongs to the aldehyde dehydrogenase family K00154,K22445 - 1.2.1.68,1.2.99.10 2.506e-219 689.0
SHD3_k127_4868295_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 552.0
SHD3_k127_4868295_4 Belongs to the DEAD box helicase family K03732,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 546.0
SHD3_k127_4868295_5 KR domain K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 417.0
SHD3_k127_4868295_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 428.0
SHD3_k127_4868295_7 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 334.0
SHD3_k127_4868295_8 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002574 299.0
SHD3_k127_4868295_9 COG2199 FOG GGDEF domain K07216,K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001901 282.0
SHD3_k127_4889325_0 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 579.0
SHD3_k127_4889325_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000002538 242.0
SHD3_k127_4889325_2 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000002068 188.0
SHD3_k127_4889325_3 Aspartate tyrosine aromatic aminotransferase - - - 0.00000000002421 65.0
SHD3_k127_4904928_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 557.0
SHD3_k127_4904928_1 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 474.0
SHD3_k127_4904928_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000001284 184.0
SHD3_k127_4904928_11 DNA polymerase III chi subunit, HolC K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000004562 181.0
SHD3_k127_4904928_12 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000006916 143.0
SHD3_k127_4904928_2 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 477.0
SHD3_k127_4904928_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 353.0
SHD3_k127_4904928_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 316.0
SHD3_k127_4904928_5 ABC transporter K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 303.0
SHD3_k127_4904928_6 Chaperone SurA K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000009149 261.0
SHD3_k127_4904928_7 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000002758 246.0
SHD3_k127_4904928_8 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000996 208.0
SHD3_k127_4904928_9 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000009084 196.0
SHD3_k127_490530_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.752e-291 904.0
SHD3_k127_490530_1 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 588.0
SHD3_k127_490530_10 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001388 227.0
SHD3_k127_490530_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000000000000000000000000000000624 199.0
SHD3_k127_490530_12 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000005203 174.0
SHD3_k127_490530_13 Lactoylglutathione lyase - - - 0.00000000000000000000000000000000000000000000007933 174.0
SHD3_k127_490530_14 OmpA family K03640 - - 0.000000000000000000000000000000000000000000002318 169.0
SHD3_k127_490530_15 Biopolymer transport protein K03559,K03560 - - 0.00000000000000000000000000000000000000000001124 171.0
SHD3_k127_490530_16 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000974 156.0
SHD3_k127_490530_17 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000001024 141.0
SHD3_k127_490530_18 TIGRFAM protein TolA - - - 0.00000000000000000000000000002825 130.0
SHD3_k127_490530_19 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000002078 109.0
SHD3_k127_490530_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 499.0
SHD3_k127_490530_3 YmdB-like protein K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 397.0
SHD3_k127_490530_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 398.0
SHD3_k127_490530_5 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 325.0
SHD3_k127_490530_6 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 314.0
SHD3_k127_490530_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941,K18824 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 312.0
SHD3_k127_490530_8 COG0811 Biopolymer transport proteins K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003159 264.0
SHD3_k127_490530_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000009938 244.0
SHD3_k127_4906187_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.713e-233 729.0
SHD3_k127_4906187_1 NADH:flavin oxidoreductase / NADH oxidase family K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 476.0
SHD3_k127_4906187_10 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 313.0
SHD3_k127_4906187_11 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 309.0
SHD3_k127_4906187_12 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 293.0
SHD3_k127_4906187_13 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000125 291.0
SHD3_k127_4906187_14 Protein of unknown function (DUF1428) - - - 0.000000000000000000000000000000000000000000000000000000000000003718 217.0
SHD3_k127_4906187_15 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.0000000000000000000000000000000000000000000000000000000000001855 215.0
SHD3_k127_4906187_16 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000005847 201.0
SHD3_k127_4906187_17 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000001225 187.0
SHD3_k127_4906187_18 Cupin domain - - - 0.000000000000000000000000000000000000000000001321 169.0
SHD3_k127_4906187_19 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000004978 157.0
SHD3_k127_4906187_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 489.0
SHD3_k127_4906187_20 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000002141 154.0
SHD3_k127_4906187_21 - - - - 0.000000000000000000000000000000000000002204 153.0
SHD3_k127_4906187_22 - - - - 0.000000000000000000000000000000000002687 146.0
SHD3_k127_4906187_23 response to cobalt ion - - - 0.0000000000000000001298 98.0
SHD3_k127_4906187_24 - - - - 0.00000007658 55.0
SHD3_k127_4906187_27 - - - - 0.000005218 54.0
SHD3_k127_4906187_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 465.0
SHD3_k127_4906187_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 449.0
SHD3_k127_4906187_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 425.0
SHD3_k127_4906187_6 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 382.0
SHD3_k127_4906187_7 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 357.0
SHD3_k127_4906187_8 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 354.0
SHD3_k127_4906187_9 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 330.0
SHD3_k127_4970778_0 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K02182 - 6.2.1.48 1.196e-270 845.0
SHD3_k127_4970778_1 ABC transporter transmembrane region K06147 - - 7.373e-205 653.0
SHD3_k127_4970778_10 SMP-30/Gluconolaconase/LRE-like region K01045 - 3.1.1.2,3.1.8.1 0.0000000000000000000000000000000000000000000000000000000001661 217.0
SHD3_k127_4970778_11 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000183 209.0
SHD3_k127_4970778_12 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000003205 201.0
SHD3_k127_4970778_13 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000003483 183.0
SHD3_k127_4970778_14 Protein of unknown function (DUF1465) K13592 - - 0.000000000000000000000000000000000000000003758 160.0
SHD3_k127_4970778_15 - - - - 0.00000000000000000000000000000001775 128.0
SHD3_k127_4970778_16 50S ribosomal protein L31 K02909 - - 0.0000000000000000000000000001013 121.0
SHD3_k127_4970778_17 - - - - 0.0000000000000000000001678 104.0
SHD3_k127_4970778_18 TIGRFAM flagellar export protein FliJ - - - 0.0000000000000000006177 91.0
SHD3_k127_4970778_19 - - - - 0.000000000000000008043 84.0
SHD3_k127_4970778_2 flagellum-specific ATP synthase K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 567.0
SHD3_k127_4970778_20 PFAM DoxX family protein K15977 - - 0.000000000009018 71.0
SHD3_k127_4970778_21 Protein of unknown function (DUF1192) - - - 0.0003713 51.0
SHD3_k127_4970778_3 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 460.0
SHD3_k127_4970778_4 Transcriptional regulatory protein, C terminal K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 404.0
SHD3_k127_4970778_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 387.0
SHD3_k127_4970778_6 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 318.0
SHD3_k127_4970778_7 Chloramphenicol phosphotransferase-like protein K18554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 294.0
SHD3_k127_4970778_8 Protein of unknown function (DUF1013) K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000138 268.0
SHD3_k127_4970778_9 DedA family - - - 0.000000000000000000000000000000000000000000000000000000000009131 214.0
SHD3_k127_5024124_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 8.241e-293 913.0
SHD3_k127_5024124_1 Sigma-54 interaction domain K10943 - - 6.852e-201 634.0
SHD3_k127_5024124_2 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 499.0
SHD3_k127_5024124_3 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 427.0
SHD3_k127_5024124_4 Flagellar hook protein FlgE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005353 267.0
SHD3_k127_5024124_5 Protein of unknown function (DUF1153) - - - 0.0000000000000000000000000000000000000000005297 158.0
SHD3_k127_5024124_6 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000197 146.0
SHD3_k127_5024124_7 Flagellar assembly protein FliH K02411 - - 0.00000000000000000002562 99.0
SHD3_k127_5024124_8 COG1419 Flagellar GTP-binding protein K02404 - - 0.000000000000000003405 94.0
SHD3_k127_5043924_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.336e-267 837.0
SHD3_k127_5043924_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 573.0
SHD3_k127_5043924_10 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 292.0
SHD3_k127_5043924_11 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001249 262.0
SHD3_k127_5043924_12 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000946 248.0
SHD3_k127_5043924_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000001003 207.0
SHD3_k127_5043924_14 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000003807 184.0
SHD3_k127_5043924_15 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000007349 160.0
SHD3_k127_5043924_16 PAP2 superfamily - - - 0.000000000000000000000000000003074 132.0
SHD3_k127_5043924_17 - - - - 0.00000000000000000000000000001201 124.0
SHD3_k127_5043924_18 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000001447 118.0
SHD3_k127_5043924_19 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000008251 123.0
SHD3_k127_5043924_2 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 572.0
SHD3_k127_5043924_20 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000792 96.0
SHD3_k127_5043924_21 - - - - 0.000000000000000004235 89.0
SHD3_k127_5043924_22 COG2885 outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - 0.0000000001026 73.0
SHD3_k127_5043924_3 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 548.0
SHD3_k127_5043924_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 511.0
SHD3_k127_5043924_5 Major facilitator superfamily MFS_1 K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 497.0
SHD3_k127_5043924_6 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 477.0
SHD3_k127_5043924_7 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 463.0
SHD3_k127_5043924_8 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 445.0
SHD3_k127_5043924_9 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 353.0
SHD3_k127_5049542_0 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein - - - 1.545e-265 826.0
SHD3_k127_5049542_1 Cellulase (glycosyl hydrolase family 5) - - - 6.158e-245 772.0
SHD3_k127_5049542_10 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 451.0
SHD3_k127_5049542_11 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 427.0
SHD3_k127_5049542_12 Sigma-70 factor, region 1.2 K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 413.0
SHD3_k127_5049542_13 enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 391.0
SHD3_k127_5049542_14 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 388.0
SHD3_k127_5049542_15 LysR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 384.0
SHD3_k127_5049542_16 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 372.0
SHD3_k127_5049542_17 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 363.0
SHD3_k127_5049542_18 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 356.0
SHD3_k127_5049542_19 Esterase lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 346.0
SHD3_k127_5049542_2 Flavin-binding monooxygenase-like K14520 - 1.14.13.84 2.726e-243 767.0
SHD3_k127_5049542_20 Tetrapyrrole (Corrin/Porphyrin) Methylases K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 325.0
SHD3_k127_5049542_21 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 315.0
SHD3_k127_5049542_22 Aldo/keto reductase family K00064 - 1.1.1.122 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 310.0
SHD3_k127_5049542_23 Protein of unknown function (DUF1348) K09958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 292.0
SHD3_k127_5049542_24 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 295.0
SHD3_k127_5049542_25 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009655 278.0
SHD3_k127_5049542_26 Enoyl-(Acyl carrier protein) reductase K18335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000016 284.0
SHD3_k127_5049542_27 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006282 271.0
SHD3_k127_5049542_28 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003135 280.0
SHD3_k127_5049542_29 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001893 267.0
SHD3_k127_5049542_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain K15778 - 5.4.2.2,5.4.2.8 3.889e-242 758.0
SHD3_k127_5049542_30 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005001 262.0
SHD3_k127_5049542_31 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004204 251.0
SHD3_k127_5049542_32 Pyridoxamine 5'-phosphate K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004624 246.0
SHD3_k127_5049542_33 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001409 242.0
SHD3_k127_5049542_34 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000002292 256.0
SHD3_k127_5049542_35 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000000000000000000000000000000001865 232.0
SHD3_k127_5049542_36 LysE type translocator - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0042968,GO:0042970,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000619 205.0
SHD3_k127_5049542_37 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000004821 198.0
SHD3_k127_5049542_38 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000008714 194.0
SHD3_k127_5049542_39 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000002938 175.0
SHD3_k127_5049542_4 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 4.045e-233 731.0
SHD3_k127_5049542_40 dioxygenase activity K00477 - 1.14.11.18 0.00000000000000000000000000000000000000001046 171.0
SHD3_k127_5049542_41 chorismate mutase K04092 - 5.4.99.5 0.000000000000000000000000000000000000000641 151.0
SHD3_k127_5049542_42 Protein of unknown function (DUF3775) - - - 0.00000000000000000000000000000000000002711 148.0
SHD3_k127_5049542_43 Sulfatase - - - 0.000000000000000000000000000008978 122.0
SHD3_k127_5049542_44 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000003087 116.0
SHD3_k127_5049542_45 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000005997 111.0
SHD3_k127_5049542_46 Cytochrome c - - - 0.0000000000000000000000009195 111.0
SHD3_k127_5049542_47 - - - - 0.0000000000000000000001718 102.0
SHD3_k127_5049542_48 Protein of unknown function (DUF1289) K06938 - - 0.0000000000000001038 81.0
SHD3_k127_5049542_49 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000008313 79.0
SHD3_k127_5049542_5 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 591.0
SHD3_k127_5049542_50 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000004072 78.0
SHD3_k127_5049542_6 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 576.0
SHD3_k127_5049542_7 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 573.0
SHD3_k127_5049542_8 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 559.0
SHD3_k127_5049542_9 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 524.0
SHD3_k127_5053379_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1385.0
SHD3_k127_5053379_1 Peptidase family M1 domain - - - 0.0 1349.0
SHD3_k127_5053379_10 beta-N-acetylglucosaminidase K01197 - 3.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 452.0
SHD3_k127_5053379_11 Dienelactone hydrolase and related enzymes K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 327.0
SHD3_k127_5053379_12 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 317.0
SHD3_k127_5053379_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 305.0
SHD3_k127_5053379_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002066 259.0
SHD3_k127_5053379_15 regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000001893 206.0
SHD3_k127_5053379_16 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000004167 187.0
SHD3_k127_5053379_17 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000116 165.0
SHD3_k127_5053379_18 Dehydrogenase - - - 0.000000000000000000000000000000000000533 158.0
SHD3_k127_5053379_19 SOS response K14160 - - 0.000000000000000005054 94.0
SHD3_k127_5053379_2 in Yersinia the HmsR protein is an inner membrane protein K11936 - - 0.0 1267.0
SHD3_k127_5053379_20 Bacterial regulatory proteins, tetR family - - - 0.000000000000211 76.0
SHD3_k127_5053379_21 - - - - 0.00005568 52.0
SHD3_k127_5053379_3 Sulfatase - - - 4.22e-257 800.0
SHD3_k127_5053379_4 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 554.0
SHD3_k127_5053379_5 impB/mucB/samB family K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 530.0
SHD3_k127_5053379_6 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 471.0
SHD3_k127_5053379_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 467.0
SHD3_k127_5053379_8 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 458.0
SHD3_k127_5053379_9 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 485.0
SHD3_k127_5098665_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1002.0
SHD3_k127_5098665_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 7.036e-277 862.0
SHD3_k127_5098665_10 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 488.0
SHD3_k127_5098665_11 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 452.0
SHD3_k127_5098665_12 Binding-protein-dependent transport system inner membrane component K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 436.0
SHD3_k127_5098665_13 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 440.0
SHD3_k127_5098665_14 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 444.0
SHD3_k127_5098665_15 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 424.0
SHD3_k127_5098665_16 ABC transporter K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 413.0
SHD3_k127_5098665_17 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 406.0
SHD3_k127_5098665_18 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 396.0
SHD3_k127_5098665_19 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 392.0
SHD3_k127_5098665_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.552e-232 725.0
SHD3_k127_5098665_20 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 376.0
SHD3_k127_5098665_21 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 374.0
SHD3_k127_5098665_22 phosphate transport system permease K02038 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 365.0
SHD3_k127_5098665_23 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 364.0
SHD3_k127_5098665_24 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 359.0
SHD3_k127_5098665_25 Chromosome partitioning protein ParA K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 361.0
SHD3_k127_5098665_26 PFAM pfkB family carbohydrate kinase K00847,K00856 - 2.7.1.20,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 355.0
SHD3_k127_5098665_27 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 323.0
SHD3_k127_5098665_28 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 319.0
SHD3_k127_5098665_29 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 321.0
SHD3_k127_5098665_3 VWA domain containing CoxE-like protein K09989 - - 4.911e-203 640.0
SHD3_k127_5098665_30 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 317.0
SHD3_k127_5098665_31 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 312.0
SHD3_k127_5098665_32 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 308.0
SHD3_k127_5098665_33 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 312.0
SHD3_k127_5098665_34 Acetyltransferase (GNAT) domain K22310 - 2.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 302.0
SHD3_k127_5098665_35 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 296.0
SHD3_k127_5098665_36 PFAM Phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 308.0
SHD3_k127_5098665_37 Methyltransferase K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 293.0
SHD3_k127_5098665_38 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004384 291.0
SHD3_k127_5098665_39 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005323 284.0
SHD3_k127_5098665_4 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 8.397e-202 649.0
SHD3_k127_5098665_40 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001128 280.0
SHD3_k127_5098665_41 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005691 286.0
SHD3_k127_5098665_42 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001775 276.0
SHD3_k127_5098665_43 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007171 270.0
SHD3_k127_5098665_44 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001505 268.0
SHD3_k127_5098665_45 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000001631 260.0
SHD3_k127_5098665_46 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000242 254.0
SHD3_k127_5098665_47 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000001716 245.0
SHD3_k127_5098665_48 Molybdenum ABC transporter K02020 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - 0.0000000000000000000000000000000000000000000000000000000000000000000002858 247.0
SHD3_k127_5098665_49 EamA-like transporter family K08978 - - 0.0000000000000000000000000000000000000000000000000000000000000000459 225.0
SHD3_k127_5098665_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.06e-196 627.0
SHD3_k127_5098665_50 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000001505 198.0
SHD3_k127_5098665_51 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000005511 191.0
SHD3_k127_5098665_52 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000003181 192.0
SHD3_k127_5098665_53 import inner membrane translocase, subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000001747 194.0
SHD3_k127_5098665_54 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000002113 187.0
SHD3_k127_5098665_55 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000002482 188.0
SHD3_k127_5098665_56 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000003762 185.0
SHD3_k127_5098665_57 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000003355 175.0
SHD3_k127_5098665_58 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000001133 174.0
SHD3_k127_5098665_59 Etoposide-induced protein 2.4 (EI24) K06203 - - 0.00000000000000000000000000000006924 133.0
SHD3_k127_5098665_6 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 492.0
SHD3_k127_5098665_60 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000002993 127.0
SHD3_k127_5098665_61 Integral membrane protein (DUF2244) - - - 0.000000000000000000000000000865 119.0
SHD3_k127_5098665_62 protein conserved in bacteria - - - 0.000000000000000000000000001391 120.0
SHD3_k127_5098665_63 domain, Protein - - - 0.00000000000000002631 85.0
SHD3_k127_5098665_64 - - - - 0.0000000000000002294 86.0
SHD3_k127_5098665_65 Protein of unknown function (DUF3311) - - - 0.000000000000001707 79.0
SHD3_k127_5098665_66 - - - - 0.000000000000007514 87.0
SHD3_k127_5098665_68 His Kinase A (phosphoacceptor) domain - - - 0.0000007315 59.0
SHD3_k127_5098665_7 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 489.0
SHD3_k127_5098665_70 - - - - 0.0006003 48.0
SHD3_k127_5098665_8 PFAM Major Facilitator Superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 492.0
SHD3_k127_5098665_9 Major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 489.0
SHD3_k127_5103447_0 Flavin containing amine oxidoreductase - - - 1.636e-255 801.0
SHD3_k127_5103447_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 3.157e-203 640.0
SHD3_k127_5103447_2 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 458.0
SHD3_k127_5103447_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000001445 255.0
SHD3_k127_5103447_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000002057 250.0
SHD3_k127_5103447_6 Flavin containing amine oxidoreductase - - - 0.00000000000000000008351 90.0
SHD3_k127_5110537_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 488.0
SHD3_k127_5110537_1 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 433.0
SHD3_k127_5110537_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 356.0
SHD3_k127_5110537_3 Phytoene synthase K21678 - 2.5.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 338.0
SHD3_k127_5110537_4 Squalene/phytoene synthase K21679 - 4.2.3.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 332.0
SHD3_k127_5201217_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1157.0
SHD3_k127_5201217_1 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1079.0
SHD3_k127_5201217_10 Cytochrome P450 K15877 - 1.7.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 611.0
SHD3_k127_5201217_11 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18334 - 4.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 589.0
SHD3_k127_5201217_12 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 600.0
SHD3_k127_5201217_13 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 530.0
SHD3_k127_5201217_14 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 532.0
SHD3_k127_5201217_15 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 512.0
SHD3_k127_5201217_16 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 484.0
SHD3_k127_5201217_17 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 469.0
SHD3_k127_5201217_18 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 434.0
SHD3_k127_5201217_19 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 430.0
SHD3_k127_5201217_2 Flavoprotein involved in K transport - - - 1.548e-285 881.0
SHD3_k127_5201217_20 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 417.0
SHD3_k127_5201217_21 Enoyl-CoA hydratase/isomerase K01692,K05605 - 3.1.2.4,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 414.0
SHD3_k127_5201217_22 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 398.0
SHD3_k127_5201217_23 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 384.0
SHD3_k127_5201217_24 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 380.0
SHD3_k127_5201217_25 Domain of unknown function (DUF1794) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 340.0
SHD3_k127_5201217_26 TIGRFAM hopanoid biosynthesis associated protein HpnK K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 341.0
SHD3_k127_5201217_27 Hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 336.0
SHD3_k127_5201217_28 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 327.0
SHD3_k127_5201217_29 - - - - 0.00000000000000000000000000000000000000000000000000136 198.0
SHD3_k127_5201217_3 hopanoid biosynthesis associated radical SAM protein HpnJ - - - 1.77e-266 824.0
SHD3_k127_5201217_30 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000001315 173.0
SHD3_k127_5201217_31 transmembrane transport - - - 0.00000000000000000000000000000000000000002913 170.0
SHD3_k127_5201217_32 Thioesterase superfamily - - - 0.000000000000000000000000000000000000009824 152.0
SHD3_k127_5201217_33 L-rhamnose mutarotase K03534 - 5.1.3.32 0.0000000000000000000000000000000000001202 145.0
SHD3_k127_5201217_34 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000007437 132.0
SHD3_k127_5201217_35 Protein of unknown function (DUF3307) - - - 0.000000000000000000000000008933 115.0
SHD3_k127_5201217_36 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000002359 95.0
SHD3_k127_5201217_4 Aldehyde dehydrogenase family K00140 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896 1.2.1.18,1.2.1.27 3.637e-263 820.0
SHD3_k127_5201217_5 CHAT domain - - - 1.302e-262 843.0
SHD3_k127_5201217_6 mannose metabolic process K01191 - 3.2.1.24 9.926e-238 770.0
SHD3_k127_5201217_7 Alkyl sulfatase dimerisation - - - 1.794e-215 685.0
SHD3_k127_5201217_8 acyl-CoA dehydrogenase K00249,K06446 - 1.3.8.7 8.333e-215 671.0
SHD3_k127_5201217_9 Alcohol dehydrogenase GroES-like domain K00001,K00055,K00121 - 1.1.1.1,1.1.1.284,1.1.1.90 1.434e-195 614.0
SHD3_k127_5217031_0 Belongs to the heme-copper respiratory oxidase family K04561 - 1.7.2.5 9.077e-215 674.0
SHD3_k127_5217031_1 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 386.0
SHD3_k127_5217031_2 Histidine kinase K11357 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 318.0
SHD3_k127_5217031_3 Cytochrome c K02305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006787 262.0
SHD3_k127_5217031_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004001 258.0
SHD3_k127_5217031_5 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000001171 210.0
SHD3_k127_5217031_6 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000001128 160.0
SHD3_k127_5217031_7 PFAM Chromosomal replication initiator DnaA domain - - - 0.0000000000000000002049 92.0
SHD3_k127_5227488_0 ABC transporter transmembrane region K06147,K18890 - - 1.31e-268 844.0
SHD3_k127_5227488_1 ABC transporter, transmembrane region K06147,K18889 - - 1.122e-232 737.0
SHD3_k127_5227488_2 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 379.0
SHD3_k127_5227488_3 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 314.0
SHD3_k127_5227488_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000004863 268.0
SHD3_k127_5227488_5 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002386 262.0
SHD3_k127_5227488_6 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000008048 231.0
SHD3_k127_5227488_7 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000000000000000000000000939 196.0
SHD3_k127_5227488_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000007399 189.0
SHD3_k127_5227488_9 dioxygenase activity - - - 0.000000000000000000000000000000298 134.0
SHD3_k127_5235807_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 4.67e-321 1014.0
SHD3_k127_5235807_1 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 449.0
SHD3_k127_5235807_10 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000003429 78.0
SHD3_k127_5235807_11 - - - - 0.0000000000002113 77.0
SHD3_k127_5235807_12 - - - - 0.000000000004499 72.0
SHD3_k127_5235807_2 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 323.0
SHD3_k127_5235807_3 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000004719 242.0
SHD3_k127_5235807_4 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000001037 221.0
SHD3_k127_5235807_5 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000003155 173.0
SHD3_k127_5235807_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000001486 148.0
SHD3_k127_5235807_7 Cold shock protein domain K03704 - - 0.00000000000000000000000006914 108.0
SHD3_k127_5235807_8 Cold shock K03704 - - 0.00000000000000000000000481 102.0
SHD3_k127_5235807_9 Cold shock K03704 - - 0.0000000000000000000001006 99.0
SHD3_k127_5236934_0 SpoVR family K06415 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 2.481e-206 653.0
SHD3_k127_5236934_1 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 596.0
SHD3_k127_5236934_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 407.0
SHD3_k127_5236934_11 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 396.0
SHD3_k127_5236934_12 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 374.0
SHD3_k127_5236934_13 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 362.0
SHD3_k127_5236934_14 transcriptional regulator K02624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 312.0
SHD3_k127_5236934_15 transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 305.0
SHD3_k127_5236934_16 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 292.0
SHD3_k127_5236934_17 Lysophospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000044 286.0
SHD3_k127_5236934_18 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007479 279.0
SHD3_k127_5236934_19 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 274.0
SHD3_k127_5236934_2 Acyl-CoA dehydrogenase, C-terminal domain K06446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 587.0
SHD3_k127_5236934_20 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008345 254.0
SHD3_k127_5236934_21 nicotinamide mononucleotide transporter K03811 - - 0.00000000000000000000000000000000000000000000000000000002335 203.0
SHD3_k127_5236934_22 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000002987 198.0
SHD3_k127_5236934_23 AAA domain - - - 0.0000000000000000000000000000000000000001854 156.0
SHD3_k127_5236934_24 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000258 138.0
SHD3_k127_5236934_25 Acyl-transferase - - - 0.0000000000000000000000006604 118.0
SHD3_k127_5236934_26 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000006756 109.0
SHD3_k127_5236934_27 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.0000000000000000000004576 104.0
SHD3_k127_5236934_28 PIN domain - - - 0.0000000000007903 74.0
SHD3_k127_5236934_29 PAS domain - - - 0.0000000003456 68.0
SHD3_k127_5236934_3 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 566.0
SHD3_k127_5236934_30 PAS domain - - - 0.000000002753 65.0
SHD3_k127_5236934_31 Plasmid stability protein K21495 - - 0.000005871 52.0
SHD3_k127_5236934_32 - - - - 0.000007195 53.0
SHD3_k127_5236934_4 Cobalamin-independent synthase, Catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 544.0
SHD3_k127_5236934_5 Prolyl oligopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 538.0
SHD3_k127_5236934_6 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 472.0
SHD3_k127_5236934_7 Nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 441.0
SHD3_k127_5236934_8 TonB-dependent Receptor Plug Domain K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 452.0
SHD3_k127_5236934_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 419.0
SHD3_k127_5237753_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 439.0
SHD3_k127_5237753_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 314.0
SHD3_k127_5237753_10 - - - - 0.00002812 46.0
SHD3_k127_5237753_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000002388 194.0
SHD3_k127_5237753_3 CBS domain - - - 0.000000000000000000000000000000000002701 143.0
SHD3_k127_5237753_4 translation initiation factor activity K06996 - - 0.0000000000000000000000000000001347 128.0
SHD3_k127_5237753_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000001923 105.0
SHD3_k127_5237753_6 - - - - 0.00000000000000000000569 92.0
SHD3_k127_5237753_7 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000000005557 78.0
SHD3_k127_5237753_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000007417 77.0
SHD3_k127_5237753_9 transcriptional regulator - - - 0.00000001305 58.0
SHD3_k127_5270421_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1230.0
SHD3_k127_5270421_1 COG2826 Transposase and inactivated derivatives, IS30 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 526.0
SHD3_k127_5270421_2 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000000002632 129.0
SHD3_k127_5270421_3 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.0000000000000000000000001508 111.0
SHD3_k127_5270421_4 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000004971 87.0
SHD3_k127_5270421_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000001358 83.0
SHD3_k127_5283697_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 1.584e-244 771.0
SHD3_k127_5283697_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001319 284.0
SHD3_k127_5283697_2 Curli production assembly/transport component CsgG K06214,K13586 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
SHD3_k127_5283697_3 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007016 228.0
SHD3_k127_5283697_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000134 223.0
SHD3_k127_5283697_5 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000004049 212.0
SHD3_k127_5297805_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.014e-231 730.0
SHD3_k127_5297805_1 Sugar (and other) transporter K03446 - - 2.761e-197 632.0
SHD3_k127_5297805_10 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000003322 183.0
SHD3_k127_5297805_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000003613 142.0
SHD3_k127_5297805_12 WHG domain - - - 0.000000000000000000000000000000271 130.0
SHD3_k127_5297805_13 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000292 109.0
SHD3_k127_5297805_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000002079 98.0
SHD3_k127_5297805_2 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 428.0
SHD3_k127_5297805_3 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 405.0
SHD3_k127_5297805_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 411.0
SHD3_k127_5297805_5 HlyD family secretion protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 334.0
SHD3_k127_5297805_6 chemotaxis MotB protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 321.0
SHD3_k127_5297805_7 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 310.0
SHD3_k127_5297805_8 PFAM Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000002526 250.0
SHD3_k127_5297805_9 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000001379 196.0
SHD3_k127_5331303_0 Amidohydrolase K22213 - 4.1.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 345.0
SHD3_k127_5331303_1 Transporter, major facilitator family protein K08369 - - 0.0000000000000000000000000000000000000000000000000000000000005142 222.0
SHD3_k127_5331303_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000145 165.0
SHD3_k127_5331937_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 6.663e-277 860.0
SHD3_k127_5331937_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000002306 93.0
SHD3_k127_5332743_0 Serine protein kinase K07180 - - 1.541e-269 835.0
SHD3_k127_5332743_1 Sulfatase - - - 4.425e-254 792.0
SHD3_k127_5332743_10 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003736 239.0
SHD3_k127_5332743_11 Rhodanese-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002097 228.0
SHD3_k127_5332743_12 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000003231 219.0
SHD3_k127_5332743_13 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000002335 203.0
SHD3_k127_5332743_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000002715 193.0
SHD3_k127_5332743_15 Domain of unknown function (DUF4188) - - - 0.00000000000000000000000000000000000000000000000001257 186.0
SHD3_k127_5332743_16 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000002181 181.0
SHD3_k127_5332743_17 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000001179 181.0
SHD3_k127_5332743_18 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000003309 173.0
SHD3_k127_5332743_19 Hydrolase K07025 - - 0.0000000000000000000000000000000000000000000001176 175.0
SHD3_k127_5332743_2 4Fe-4S single cluster domain K06937 - - 1.602e-213 671.0
SHD3_k127_5332743_20 GcrA cell cycle regulator K13583 - - 0.00000000000000000000000000000000000000000009747 165.0
SHD3_k127_5332743_21 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000001284 152.0
SHD3_k127_5332743_22 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000000002222 153.0
SHD3_k127_5332743_23 Protein of unknown function (DUF992) - - - 0.00000000000000000000000000000000000001646 155.0
SHD3_k127_5332743_24 PFAM Mo-dependent nitrogenase - - - 0.00000000000000000000000000000000001205 142.0
SHD3_k127_5332743_25 membrane - - - 0.00000000000000000000000000000005663 132.0
SHD3_k127_5332743_26 FR47-like protein - - - 0.0000000000000000000000000000001383 134.0
SHD3_k127_5332743_27 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.0000000000000000000000000000002358 126.0
SHD3_k127_5332743_29 Caspase domain - - - 0.000000000000000000000000000363 124.0
SHD3_k127_5332743_3 TIGRFAM acetylornithine and succinylornithine aminotransferase K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 559.0
SHD3_k127_5332743_30 Belongs to the ompA family - - - 0.000000000000000000000000004122 121.0
SHD3_k127_5332743_31 Phosphotransferase enzyme family K06979 - - 0.00000000000000001251 93.0
SHD3_k127_5332743_32 - - - - 0.00000008617 57.0
SHD3_k127_5332743_33 SnoaL-like polyketide cyclase - - - 0.0000006511 57.0
SHD3_k127_5332743_34 alpha/beta hydrolase fold - - - 0.00001119 52.0
SHD3_k127_5332743_35 - - - - 0.0009013 48.0
SHD3_k127_5332743_4 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 529.0
SHD3_k127_5332743_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 437.0
SHD3_k127_5332743_6 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 402.0
SHD3_k127_5332743_7 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 370.0
SHD3_k127_5332743_8 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 304.0
SHD3_k127_5332743_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000002951 250.0
SHD3_k127_5400926_0 Penicillin-binding protein 5, C-terminal domain K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 351.0
SHD3_k127_5400926_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 345.0
SHD3_k127_5400926_2 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000235 291.0
SHD3_k127_5400926_3 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000002389 253.0
SHD3_k127_5400926_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000009409 241.0
SHD3_k127_5400926_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000001051 239.0
SHD3_k127_5400926_6 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000004089 242.0
SHD3_k127_5400926_7 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000586 199.0
SHD3_k127_5400926_8 PFAM type IV pilus assembly PilZ - - - 0.0000000000000000000001493 107.0
SHD3_k127_5400926_9 Resolvase, N terminal domain - - - 0.0000005545 54.0
SHD3_k127_5412566_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1395.0
SHD3_k127_5412566_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1310.0
SHD3_k127_5412566_10 short-chain dehydrogenase K05296 - 1.1.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 349.0
SHD3_k127_5412566_11 Dienelactone hydrolase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 340.0
SHD3_k127_5412566_12 Major Facilitator Superfamily K08169 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 334.0
SHD3_k127_5412566_13 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 329.0
SHD3_k127_5412566_14 Oxidoreductase molybdopterin binding K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 306.0
SHD3_k127_5412566_15 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 298.0
SHD3_k127_5412566_16 PFAM Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001128 295.0
SHD3_k127_5412566_17 taurine catabolism dioxygenase K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000001572 263.0
SHD3_k127_5412566_18 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000004789 259.0
SHD3_k127_5412566_19 Chain length determinant protein K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001693 268.0
SHD3_k127_5412566_2 PFAM AMP-dependent synthetase and ligase K00666,K18688 - 6.2.1.42 4.253e-254 792.0
SHD3_k127_5412566_20 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001259 247.0
SHD3_k127_5412566_21 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000006334 238.0
SHD3_k127_5412566_22 Bacterial sugar transferase K00996,K03606 - 2.7.8.6 0.0000000000000000000000000000000000000000000000000000000000000000527 230.0
SHD3_k127_5412566_23 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000008717 227.0
SHD3_k127_5412566_24 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000001931 190.0
SHD3_k127_5412566_25 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000001768 190.0
SHD3_k127_5412566_26 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000007688 178.0
SHD3_k127_5412566_27 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000003719 182.0
SHD3_k127_5412566_28 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000001369 160.0
SHD3_k127_5412566_29 Invasion associated locus B (IalB) protein - - - 0.00000000000000000004224 98.0
SHD3_k127_5412566_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 599.0
SHD3_k127_5412566_30 Polysaccharide deacetylase - - - 0.000000000000003959 87.0
SHD3_k127_5412566_31 Sulfatase-modifying factor enzyme 1 - - - 0.000000000001636 70.0
SHD3_k127_5412566_32 PFAM Invasion associated locus B - - - 0.000000002303 67.0
SHD3_k127_5412566_33 Sulfatase-modifying factor enzyme 1 - - - 0.00000006569 55.0
SHD3_k127_5412566_34 Sulfatase-modifying factor enzyme 1 - - - 0.0000003716 51.0
SHD3_k127_5412566_35 Sulfatase-modifying factor enzyme 1 - - - 0.000002438 49.0
SHD3_k127_5412566_4 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 570.0
SHD3_k127_5412566_5 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 535.0
SHD3_k127_5412566_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 394.0
SHD3_k127_5412566_7 HlyD family secretion protein K07799,K18990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 396.0
SHD3_k127_5412566_8 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 373.0
SHD3_k127_5412566_9 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 353.0
SHD3_k127_5440941_0 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 441.0
SHD3_k127_5440941_1 Phosphotransferase enzyme family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 387.0
SHD3_k127_5440941_2 Putative diguanylate phosphodiesterase K13245 - 3.1.4.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 410.0
SHD3_k127_5440941_3 Threonine synthase N terminus K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 367.0
SHD3_k127_5440941_4 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000001513 256.0
SHD3_k127_5440941_5 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000002855 236.0
SHD3_k127_5440941_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000004379 218.0
SHD3_k127_5440941_7 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000009994 215.0
SHD3_k127_544098_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1245.0
SHD3_k127_544098_1 Cobalamin biosynthesis protein CobT VWA domain K09883 - 6.6.1.2 2.763e-239 754.0
SHD3_k127_544098_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001221 286.0
SHD3_k127_544098_11 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003791 287.0
SHD3_k127_544098_12 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005717 253.0
SHD3_k127_544098_13 PFAM NUDIX hydrolase K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000472 216.0
SHD3_k127_544098_14 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000000003719 203.0
SHD3_k127_544098_15 molecular chaperone - - - 0.00000000000000000000000000000000000000000002517 168.0
SHD3_k127_544098_16 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000008784 154.0
SHD3_k127_544098_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000001838 147.0
SHD3_k127_544098_18 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0033218,GO:0042277,GO:0043167,GO:0043168,GO:0043295,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0055114,GO:0072341,GO:1900750,GO:1901681 - 0.0000000000000000000000000000005428 123.0
SHD3_k127_544098_19 Belongs to the BolA IbaG family K05527,K22066 - - 0.0000000000000000000000005354 106.0
SHD3_k127_544098_2 PFAM AAA domain (dynein-related subfamily) K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 556.0
SHD3_k127_544098_20 - - - - 0.000000000000000000003903 109.0
SHD3_k127_544098_21 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000009656 93.0
SHD3_k127_544098_22 - - - - 0.000000000005812 73.0
SHD3_k127_544098_23 Flp Fap pilin component K02651 - - 0.0006797 48.0
SHD3_k127_544098_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 501.0
SHD3_k127_544098_4 Transporter associated domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 481.0
SHD3_k127_544098_5 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 466.0
SHD3_k127_544098_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 429.0
SHD3_k127_544098_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 426.0
SHD3_k127_544098_8 Belongs to the HpcH HpaI aldolase family K08691 - 4.1.3.24,4.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 407.0
SHD3_k127_544098_9 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 331.0
SHD3_k127_5482850_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 562.0
SHD3_k127_5482850_1 Long-chain fatty aldehyde decarbonylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 552.0
SHD3_k127_5482850_10 Protein of unknown function (DUF3592) - - - 0.000000007201 67.0
SHD3_k127_5482850_11 Maf-like protein K06287 - - 0.00000002676 57.0
SHD3_k127_5482850_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 509.0
SHD3_k127_5482850_3 Aldo Keto reductase K05275 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 361.0
SHD3_k127_5482850_4 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 323.0
SHD3_k127_5482850_5 Uncharacterised protein family (UPF0262) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001111 241.0
SHD3_k127_5482850_6 Low molecular weight phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.000000000000000000000000000000000000000000000000000001885 194.0
SHD3_k127_5482850_7 Protein of unknown function (DUF2948) - - - 0.000000000000000000000000000000000059 138.0
SHD3_k127_5482850_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000009445 134.0
SHD3_k127_5482850_9 response to cobalt ion - GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010045,GO:0010243,GO:0030288,GO:0030313,GO:0031975,GO:0032025,GO:0033554,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:1901652,GO:1901698,GO:1901700 - 0.0000000000000155 84.0
SHD3_k127_5484407_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 536.0
SHD3_k127_5484407_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 420.0
SHD3_k127_5484407_10 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000007529 169.0
SHD3_k127_5484407_11 invasion associated locus B - - - 0.00000000000000000000000000000003567 132.0
SHD3_k127_5484407_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 391.0
SHD3_k127_5484407_3 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 349.0
SHD3_k127_5484407_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 322.0
SHD3_k127_5484407_5 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 306.0
SHD3_k127_5484407_6 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004869 273.0
SHD3_k127_5484407_7 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005703 270.0
SHD3_k127_5484407_8 DSBA-like thioredoxin domain K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001637 269.0
SHD3_k127_5484407_9 SpoU rRNA Methylase family - - - 0.00000000000000000000000000000000000000000000000000000000001493 214.0
SHD3_k127_5519014_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 3.082e-198 631.0
SHD3_k127_5519014_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 403.0
SHD3_k127_5521907_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 558.0
SHD3_k127_5521907_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 489.0
SHD3_k127_5521907_10 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000000000000005563 131.0
SHD3_k127_5521907_11 YjbR - - - 0.0007445 47.0
SHD3_k127_5521907_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009866 427.0
SHD3_k127_5521907_3 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 379.0
SHD3_k127_5521907_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 285.0
SHD3_k127_5521907_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004741 272.0
SHD3_k127_5521907_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000003402 257.0
SHD3_k127_5521907_7 PFAM Alpha beta hydrolase fold-3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008708 260.0
SHD3_k127_5521907_8 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000005835 256.0
SHD3_k127_5521907_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000009614 222.0
SHD3_k127_5554674_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 5.031e-318 992.0
SHD3_k127_5554674_1 Biotin carboxylase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 602.0
SHD3_k127_5554674_10 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
SHD3_k127_5554674_11 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000000000003844 221.0
SHD3_k127_5554674_12 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000007324 168.0
SHD3_k127_5554674_13 protein conserved in bacteria - - - 0.00000000000000000000000000000000002774 139.0
SHD3_k127_5554674_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000007559 134.0
SHD3_k127_5554674_15 - - - - 0.000000000000000000000000006018 115.0
SHD3_k127_5554674_16 Thioesterase-like superfamily - - - 0.0000000000000000000000004194 115.0
SHD3_k127_5554674_2 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 531.0
SHD3_k127_5554674_3 Divergent 4Fe-4S mono-cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 526.0
SHD3_k127_5554674_4 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 488.0
SHD3_k127_5554674_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 389.0
SHD3_k127_5554674_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 374.0
SHD3_k127_5554674_7 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 323.0
SHD3_k127_5554674_8 MFS/sugar transport protein K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 308.0
SHD3_k127_5554674_9 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001843 269.0
SHD3_k127_5562051_0 helicase K03722 - 3.6.4.12 7.073e-286 904.0
SHD3_k127_5562051_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 1.709e-215 681.0
SHD3_k127_5562051_10 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 321.0
SHD3_k127_5562051_11 Peptidase S24-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 284.0
SHD3_k127_5562051_12 Inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005531 277.0
SHD3_k127_5562051_13 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008085 262.0
SHD3_k127_5562051_14 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009966 272.0
SHD3_k127_5562051_15 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000008113 233.0
SHD3_k127_5562051_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000007095 231.0
SHD3_k127_5562051_17 Aminopeptidase K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000048 219.0
SHD3_k127_5562051_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000007324 207.0
SHD3_k127_5562051_19 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000001859 186.0
SHD3_k127_5562051_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 492.0
SHD3_k127_5562051_20 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000004668 178.0
SHD3_k127_5562051_21 Acetyltransferase (GNAT) domain K22479 - - 0.0000000000000000000000000000000000000000000002187 174.0
SHD3_k127_5562051_22 Peptidase, S41 - - - 0.000000000000000000000000000000000000000000001107 184.0
SHD3_k127_5562051_23 Histidine kinase K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000009886 178.0
SHD3_k127_5562051_24 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000004093 161.0
SHD3_k127_5562051_25 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000002765 158.0
SHD3_k127_5562051_26 protein, possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000001043 127.0
SHD3_k127_5562051_27 Belongs to the UPF0434 family K09791 - - 0.00000000000000000005114 90.0
SHD3_k127_5562051_28 - - - - 0.000000000000001742 80.0
SHD3_k127_5562051_29 Protein of unknown function (DUF3298) - - - 0.00000000000298 78.0
SHD3_k127_5562051_3 Glutamine synthetase, catalytic domain K01915 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0034024,GO:0034641,GO:0042402,GO:0044106,GO:0044237,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 475.0
SHD3_k127_5562051_32 - - - - 0.00001217 53.0
SHD3_k127_5562051_33 Lysozyme inhibitor LprI - - - 0.0001392 53.0
SHD3_k127_5562051_4 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 467.0
SHD3_k127_5562051_5 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 397.0
SHD3_k127_5562051_6 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 387.0
SHD3_k127_5562051_7 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 370.0
SHD3_k127_5562051_8 Tetratricopeptide repeat K03671,K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 348.0
SHD3_k127_5562051_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 338.0
SHD3_k127_5576766_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2523.0
SHD3_k127_5576766_1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000004513 166.0
SHD3_k127_5576766_2 transduction histidine kinase - - - 0.0000000000000000000000000000000000001251 145.0
SHD3_k127_5637731_0 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 595.0
SHD3_k127_5637731_1 Belongs to the heat shock protein 70 family K04046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 547.0
SHD3_k127_5637731_10 Acetyltransferase - - - 0.00000000000000000003083 100.0
SHD3_k127_5637731_2 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 464.0
SHD3_k127_5637731_3 quinone oxidoreductase, YhdH YhfP family K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 444.0
SHD3_k127_5637731_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000001412 271.0
SHD3_k127_5637731_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001887 255.0
SHD3_k127_5637731_6 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 256.0
SHD3_k127_5637731_7 iron-sulfur cluster assembly K22073 - - 0.00000000000000000000000000000000000000000000000000000000000001035 224.0
SHD3_k127_5637731_8 LysE type translocator - - - 0.00000000000000000000000000000000000000000000133 174.0
SHD3_k127_5637731_9 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000003917 160.0
SHD3_k127_5639920_0 Alpha-2-Macroglobulin K06894 - - 0.0 1296.0
SHD3_k127_5639920_1 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 0.0 1024.0
SHD3_k127_5639920_10 AMP-binding enzyme K02182 - 6.2.1.48 1.199e-195 625.0
SHD3_k127_5639920_11 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 607.0
SHD3_k127_5639920_12 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 584.0
SHD3_k127_5639920_13 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 571.0
SHD3_k127_5639920_14 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 511.0
SHD3_k127_5639920_15 NADH flavin oxidoreductase NADH oxidase K00317,K21833 - 1.5.8.1,1.5.8.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 479.0
SHD3_k127_5639920_16 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 402.0
SHD3_k127_5639920_17 Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 401.0
SHD3_k127_5639920_18 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 397.0
SHD3_k127_5639920_19 Not a type III effector K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 379.0
SHD3_k127_5639920_2 acyl-CoA dehydrogenase K09456 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 1.966e-258 805.0
SHD3_k127_5639920_20 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 365.0
SHD3_k127_5639920_21 Major facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 349.0
SHD3_k127_5639920_22 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 344.0
SHD3_k127_5639920_23 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 344.0
SHD3_k127_5639920_24 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 326.0
SHD3_k127_5639920_25 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 307.0
SHD3_k127_5639920_26 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003301 289.0
SHD3_k127_5639920_27 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007676 270.0
SHD3_k127_5639920_28 WHG domain - - - 0.00000000000000000000000000000000000000000000000000000000000008399 218.0
SHD3_k127_5639920_29 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000247 197.0
SHD3_k127_5639920_3 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.167e-231 724.0
SHD3_k127_5639920_30 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000007169 162.0
SHD3_k127_5639920_31 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000003279 143.0
SHD3_k127_5639920_32 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000006077 140.0
SHD3_k127_5639920_33 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000001872 138.0
SHD3_k127_5639920_34 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000001047 126.0
SHD3_k127_5639920_35 Protein of unknown function (DUF1244) K09948 - - 0.000000000000000000000000000000106 138.0
SHD3_k127_5639920_36 integral membrane protein - - - 0.000000000000000000000000002159 116.0
SHD3_k127_5639920_37 Belongs to the UPF0335 family - - - 0.000000000000000000000000002168 112.0
SHD3_k127_5639920_38 COG0457 FOG TPR repeat - - - 0.00000000000000000000000004148 114.0
SHD3_k127_5639920_4 PFAM Thiamine pyrophosphate enzyme, central domain, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 3.049e-221 701.0
SHD3_k127_5639920_40 Polysaccharide deacetylase - - - 0.00000000000000000000402 98.0
SHD3_k127_5639920_41 DDE domain K07498 - - 0.000000000000000001469 90.0
SHD3_k127_5639920_42 - - - - 0.00000000000000002625 91.0
SHD3_k127_5639920_43 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000000302 76.0
SHD3_k127_5639920_44 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000009935 73.0
SHD3_k127_5639920_45 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.00000000009434 71.0
SHD3_k127_5639920_46 DDE domain K07498 - - 0.0000003356 53.0
SHD3_k127_5639920_47 4Fe-4S dicluster domain - - - 0.000004012 53.0
SHD3_k127_5639920_5 L-gulonolactone oxidase-like K00103,K00225 - 1.1.3.8,1.3.2.3 1.665e-213 672.0
SHD3_k127_5639920_6 dioxygenase K11159 - - 3.146e-205 649.0
SHD3_k127_5639920_7 Belongs to the UPF0061 (SELO) family K08997 - - 1.598e-202 642.0
SHD3_k127_5639920_8 COG0277 FAD FMN-containing dehydrogenases K00803 - 2.5.1.26 7.269e-199 634.0
SHD3_k127_5639920_9 Pyruvate kinase, alpha/beta domain K00873 - 2.7.1.40 1.077e-195 620.0
SHD3_k127_5651972_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.013e-321 1002.0
SHD3_k127_5651972_1 Sulfotransferase K01014 - 2.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 328.0
SHD3_k127_5665992_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 2.365e-200 631.0
SHD3_k127_5665992_1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 518.0
SHD3_k127_5665992_10 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003629 266.0
SHD3_k127_5665992_11 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001961 255.0
SHD3_k127_5665992_12 Ribosomal protein L9, N-terminal domain K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001739 220.0
SHD3_k127_5665992_13 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000003872 207.0
SHD3_k127_5665992_14 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000002394 148.0
SHD3_k127_5665992_15 rRNA binding K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000005693 145.0
SHD3_k127_5665992_16 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000001876 134.0
SHD3_k127_5665992_17 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000002704 134.0
SHD3_k127_5665992_18 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000485 127.0
SHD3_k127_5665992_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000009558 73.0
SHD3_k127_5665992_2 PQQ-like domain K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 498.0
SHD3_k127_5665992_3 Major Facilitator Superfamily K13021 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 482.0
SHD3_k127_5665992_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 413.0
SHD3_k127_5665992_5 Acyl transferase domain K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 385.0
SHD3_k127_5665992_6 hmm pf00106 K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 339.0
SHD3_k127_5665992_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 316.0
SHD3_k127_5665992_8 KR domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 292.0
SHD3_k127_5665992_9 Domain of unknown function (DUF1732) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009262 273.0
SHD3_k127_599041_0 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 365.0
SHD3_k127_599041_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 297.0
SHD3_k127_599041_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 293.0
SHD3_k127_627405_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 9.973e-253 793.0
SHD3_k127_627405_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 8.791e-202 642.0
SHD3_k127_627405_10 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 317.0
SHD3_k127_627405_11 PFAM Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001594 271.0
SHD3_k127_627405_12 araC family K13652,K13653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002953 255.0
SHD3_k127_627405_13 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000008056 246.0
SHD3_k127_627405_14 Protein of unknown function (DUF3089) - - - 0.0000000000000000000000000000000000000000000000000000000000001661 226.0
SHD3_k127_627405_15 Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000007696 186.0
SHD3_k127_627405_16 Protein conserved in bacteria - - - 0.00000000000000000000000000003161 131.0
SHD3_k127_627405_17 - - - - 0.0000000000002005 78.0
SHD3_k127_627405_2 sorbosone dehydrogenase - - - 2.1e-198 626.0
SHD3_k127_627405_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 568.0
SHD3_k127_627405_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 452.0
SHD3_k127_627405_5 Bacterial extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 448.0
SHD3_k127_627405_6 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 421.0
SHD3_k127_627405_7 sulfate transport system, permease K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 403.0
SHD3_k127_627405_8 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 342.0
SHD3_k127_627405_9 Binding-protein-dependent transport system inner membrane component K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 341.0
SHD3_k127_702455_0 AMP-binding enzyme C-terminal domain K00666,K02182,K20034 - 6.2.1.44,6.2.1.48 6.195e-250 782.0
SHD3_k127_702455_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 367.0
SHD3_k127_702455_2 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0000000000000000000000000000000000000000000000005258 184.0
SHD3_k127_702455_3 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000001179 145.0
SHD3_k127_702455_4 PAS domain - - - 0.0005841 49.0
SHD3_k127_731024_0 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 519.0
SHD3_k127_731024_1 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 394.0
SHD3_k127_731024_2 Subtilase family - - - 0.0000000000000000001767 102.0
SHD3_k127_731024_3 Transposase IS116/IS110/IS902 family - - - 0.00000000000003602 79.0
SHD3_k127_731024_4 Cupin 2, conserved barrel domain protein - - - 0.000002092 49.0
SHD3_k127_757442_0 carbamoyl-phosphate synthase - - - 0.0 1331.0
SHD3_k127_757442_1 Involved in de novo purine biosynthesis K00602 - 2.1.2.3,3.5.4.10 3.489e-221 697.0
SHD3_k127_757442_10 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003608 273.0
SHD3_k127_757442_11 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000006408 221.0
SHD3_k127_757442_12 Pantothenic acid kinase K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.00000000000000000000000000000000000000000000000000001105 200.0
SHD3_k127_757442_13 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000007012 192.0
SHD3_k127_757442_14 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000009066 186.0
SHD3_k127_757442_15 signal transduction histidine kinase K13588 - - 0.00000000000000000000000000000000000000000000004429 177.0
SHD3_k127_757442_16 Protein of unknown function, DUF417 - - - 0.000000000000000000000000000000000000002412 151.0
SHD3_k127_757442_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000001618 135.0
SHD3_k127_757442_18 protein conserved in bacteria K01876 - 6.1.1.12 0.00000000000000000000000000001422 123.0
SHD3_k127_757442_19 NfeD-like C-terminal, partner-binding K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000003365 97.0
SHD3_k127_757442_2 Aminotransferase class-III K00833 - 2.6.1.62 1.413e-194 614.0
SHD3_k127_757442_20 CAAX protease self-immunity - - - 0.00000000000000001301 85.0
SHD3_k127_757442_21 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000007097 87.0
SHD3_k127_757442_22 - - - - 0.000000001074 62.0
SHD3_k127_757442_23 - - - - 0.000000008316 59.0
SHD3_k127_757442_25 Protein of unknown function (DUF2905) - - - 0.00003375 50.0
SHD3_k127_757442_3 transporter K08369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 548.0
SHD3_k127_757442_4 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 506.0
SHD3_k127_757442_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 483.0
SHD3_k127_757442_6 prohibitin homologues - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 400.0
SHD3_k127_757442_7 TonB-dependent Receptor Plug K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 388.0
SHD3_k127_757442_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 312.0
SHD3_k127_757442_9 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 304.0
SHD3_k127_764013_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 2.224e-270 840.0
SHD3_k127_764013_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K01284 GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 1.201e-241 764.0
SHD3_k127_764013_10 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 329.0
SHD3_k127_764013_11 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 340.0
SHD3_k127_764013_12 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000003301 246.0
SHD3_k127_764013_13 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005162 235.0
SHD3_k127_764013_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001953 220.0
SHD3_k127_764013_15 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000000000000000000000000000004659 195.0
SHD3_k127_764013_16 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000001087 191.0
SHD3_k127_764013_17 Regulatory protein MarR - - - 0.00000000000000000000000000000000000000000003916 168.0
SHD3_k127_764013_18 MarR family - - - 0.00000000000000000000000000000000000000002878 157.0
SHD3_k127_764013_19 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000004022 163.0
SHD3_k127_764013_2 oligoendopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 615.0
SHD3_k127_764013_20 Pfam:DUF4102 - - - 0.0000000000000000000000000003712 117.0
SHD3_k127_764013_21 TonB dependent receptor K02014 - - 0.0000001918 55.0
SHD3_k127_764013_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 599.0
SHD3_k127_764013_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 583.0
SHD3_k127_764013_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 537.0
SHD3_k127_764013_6 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 485.0
SHD3_k127_764013_7 Peptide ABC transporter substrate-binding protein K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 404.0
SHD3_k127_764013_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 357.0
SHD3_k127_764013_9 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 340.0
SHD3_k127_766575_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 8.81e-221 698.0
SHD3_k127_766575_1 Pfam Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 385.0
SHD3_k127_766575_10 - - - - 0.00008272 52.0
SHD3_k127_766575_2 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 355.0
SHD3_k127_766575_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 357.0
SHD3_k127_766575_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 299.0
SHD3_k127_766575_5 Alpha beta hydrolase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003198 278.0
SHD3_k127_766575_6 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007679 269.0
SHD3_k127_766575_7 BetI-type transcriptional repressor, C-terminal - - - 0.000000000005593 74.0
SHD3_k127_766575_8 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.000000963 57.0
SHD3_k127_782195_0 Class II Aldolase and Adducin N-terminal domain - - - 9.604e-234 735.0
SHD3_k127_782195_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 485.0
SHD3_k127_782195_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 417.0
SHD3_k127_782195_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000926 258.0
SHD3_k127_782195_4 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000004758 178.0
SHD3_k127_782195_5 Macrocin-O-methyltransferase (TylF) - - - 0.000000003486 69.0
SHD3_k127_82148_0 C-terminal, D2-small domain, of ClpB protein K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1189.0
SHD3_k127_82148_1 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 2.548e-274 856.0
SHD3_k127_82148_10 KR domain - - - 0.000000000000000000000000000000000000000000000000000000913 195.0
SHD3_k127_82148_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000001045 179.0
SHD3_k127_82148_12 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000002303 177.0
SHD3_k127_82148_13 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000003467 175.0
SHD3_k127_82148_14 UMP catabolic process - - - 0.0000000000000000000000000000000000000000000007454 173.0
SHD3_k127_82148_15 - - - - 0.0000000000000000000000000000000000000000000008123 169.0
SHD3_k127_82148_16 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000003389 151.0
SHD3_k127_82148_17 D-alanyl-D-alanine carboxypeptidase K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000001187 153.0
SHD3_k127_82148_18 GIY-YIG catalytic domain - - - 0.0000000000000000000000000000005829 124.0
SHD3_k127_82148_19 RNHCP domain - - - 0.000000000000000000000000000007953 123.0
SHD3_k127_82148_2 diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 563.0
SHD3_k127_82148_20 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000001214 101.0
SHD3_k127_82148_21 Phasin protein - - - 0.000000000000007223 80.0
SHD3_k127_82148_22 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000002967 76.0
SHD3_k127_82148_23 Protein of unknown function (DUF3572) - - - 0.0000000005498 63.0
SHD3_k127_82148_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 503.0
SHD3_k127_82148_4 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 474.0
SHD3_k127_82148_5 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 428.0
SHD3_k127_82148_6 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 362.0
SHD3_k127_82148_7 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 350.0
SHD3_k127_82148_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007825 253.0
SHD3_k127_82148_9 Response regulator receiver K11443 - - 0.0000000000000000000000000000000000000000000000000000000000002196 220.0
SHD3_k127_829236_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.602e-197 628.0
SHD3_k127_829236_1 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 526.0
SHD3_k127_829236_10 Transketolase central region K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 334.0
SHD3_k127_829236_11 PFAM Methyltransferase type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 319.0
SHD3_k127_829236_12 PFAM Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 288.0
SHD3_k127_829236_13 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002059 281.0
SHD3_k127_829236_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006333 268.0
SHD3_k127_829236_15 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005286 259.0
SHD3_k127_829236_16 Protein conserved in bacteria K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000539 247.0
SHD3_k127_829236_17 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000002417 253.0
SHD3_k127_829236_18 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000001282 220.0
SHD3_k127_829236_19 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000178 218.0
SHD3_k127_829236_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 473.0
SHD3_k127_829236_20 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000001941 223.0
SHD3_k127_829236_21 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000002889 215.0
SHD3_k127_829236_22 Belongs to the flagella basal body rod proteins family K02391,K02392 - - 0.0000000000000000000000000000000000000000000000000000000000696 215.0
SHD3_k127_829236_23 - - - - 0.000000000000000000000000000000000000000000006442 171.0
SHD3_k127_829236_24 Domain of unknown function (DUF4260) - - - 0.00000000000000000000000000000000000009324 146.0
SHD3_k127_829236_25 Peptidase family M23 - - - 0.0000000000000000000000000000000002578 148.0
SHD3_k127_829236_26 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000001808 134.0
SHD3_k127_829236_27 PFAM MgtE intracellular - - - 0.0000000000000000000000000001804 130.0
SHD3_k127_829236_28 Rod binding protein - - - 0.0000000000000000000009711 100.0
SHD3_k127_829236_29 SAF K02386 - - 0.00000000001595 72.0
SHD3_k127_829236_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 505.0
SHD3_k127_829236_30 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.00000001568 56.0
SHD3_k127_829236_31 - - - - 0.0000001458 63.0
SHD3_k127_829236_32 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000006102 61.0
SHD3_k127_829236_33 Sulfotransferase domain - - - 0.0000009986 60.0
SHD3_k127_829236_4 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 467.0
SHD3_k127_829236_5 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase K07257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 446.0
SHD3_k127_829236_6 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 411.0
SHD3_k127_829236_7 acid synthase K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 385.0
SHD3_k127_829236_8 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 354.0
SHD3_k127_829236_9 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 333.0
SHD3_k127_866140_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 2.651e-232 735.0
SHD3_k127_866140_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 545.0
SHD3_k127_866140_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 465.0
SHD3_k127_866140_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000717 217.0
SHD3_k127_866140_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000007664 89.0
SHD3_k127_928933_0 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 439.0
SHD3_k127_928933_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009959 272.0
SHD3_k127_969981_0 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 589.0
SHD3_k127_969981_1 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 557.0
SHD3_k127_969981_2 phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 484.0
SHD3_k127_969981_3 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006787 258.0
SHD3_k127_969981_4 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000005563 188.0
SHD3_k127_969981_5 MAPEG family K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000007085 168.0
SHD3_k127_979225_0 GTP-binding protein TypA K06207 - - 5.353e-273 853.0
SHD3_k127_979225_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 9.015e-218 692.0
SHD3_k127_979225_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001061 233.0
SHD3_k127_979225_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000006184 216.0
SHD3_k127_983549_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 1.36e-237 751.0
SHD3_k127_983549_1 Aminotransferase K14261 - - 3.749e-196 617.0
SHD3_k127_983549_10 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 286.0
SHD3_k127_983549_11 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000911 277.0
SHD3_k127_983549_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000757 246.0
SHD3_k127_983549_13 structural constituent of ribosome K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000684 214.0
SHD3_k127_983549_14 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000221 205.0
SHD3_k127_983549_15 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000731 139.0
SHD3_k127_983549_16 Putative FMN-binding domain K07734 - - 0.0000000000000000000000000000000003686 140.0
SHD3_k127_983549_17 OmpA family - - - 0.00000000000000000000000001477 124.0
SHD3_k127_983549_18 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.0000000000000000000000002155 111.0
SHD3_k127_983549_19 Protein of unknown function (DUF805) - - - 0.000000000504 67.0
SHD3_k127_983549_2 Cys/Met metabolism PLP-dependent enzyme K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008713 595.0
SHD3_k127_983549_3 DHH family K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 552.0
SHD3_k127_983549_4 Alpha-amylase domain K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 475.0
SHD3_k127_983549_5 Fructose-1,6-bisphosphatase K02446,K11532 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 442.0
SHD3_k127_983549_6 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 437.0
SHD3_k127_983549_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 404.0
SHD3_k127_983549_8 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 351.0
SHD3_k127_983549_9 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 334.0