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Overview

ID MAG03387
Name SHD3_bin.12
Sample SMP0084
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family Gp7-AA6
Genus JAWOLE01
Species
Assembly information
Completeness (%) 64.48
Contamination (%) 0.55
GC content (%) 68.0
N50 (bp) 8,394
Genome size (bp) 1,955,053

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1698

Gene name Description KEGG GOs EC E-value Score Sequence
SHD3_k127_1042970_0 Peptidase family M13 K07386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 520.0
SHD3_k127_1042970_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000004842 242.0
SHD3_k127_1042970_2 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000005738 151.0
SHD3_k127_1048632_0 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 425.0
SHD3_k127_1048632_1 COG1530 Ribonucleases G and E K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 400.0
SHD3_k127_1048632_2 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 398.0
SHD3_k127_1048632_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 301.0
SHD3_k127_1048632_4 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000001036 263.0
SHD3_k127_1048632_5 DNA ligase N terminus - - - 0.000000000000000000000000000000000000000000000000000000000000001576 232.0
SHD3_k127_1048632_6 Cell cycle protein K05837 - - 0.00000000000000000000000000000000000000000000000000006803 191.0
SHD3_k127_1048632_7 Participates in initiation and elongation during chromosome replication - - - 0.000000003272 62.0
SHD3_k127_1100447_0 - K12065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 316.0
SHD3_k127_1100447_1 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 295.0
SHD3_k127_1100447_10 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000072 68.0
SHD3_k127_1100447_11 - - - - 0.000001336 60.0
SHD3_k127_1100447_12 - - - - 0.00002448 57.0
SHD3_k127_1100447_2 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000007096 262.0
SHD3_k127_1100447_3 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000009329 248.0
SHD3_k127_1100447_4 TonB-dependent Receptor Plug Domain K16092 - - 0.00000000000000000000000000000000000000000000000000000000000005487 237.0
SHD3_k127_1100447_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000002928 191.0
SHD3_k127_1100447_6 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000001116 183.0
SHD3_k127_1100447_7 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000001724 162.0
SHD3_k127_1100447_8 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.0000000000000000000000000004779 126.0
SHD3_k127_1100447_9 Protein of unknown function (DUF1573) - - - 0.000000000000004088 88.0
SHD3_k127_111389_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 475.0
SHD3_k127_111389_1 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000000004335 152.0
SHD3_k127_111389_2 HIRAN - - - 0.000000000000000000000000000117 119.0
SHD3_k127_111389_3 DnaJ molecular chaperone homology domain - - - 0.000000000000000000001719 107.0
SHD3_k127_1117123_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 532.0
SHD3_k127_1117123_1 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 502.0
SHD3_k127_1117123_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 395.0
SHD3_k127_1117123_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 311.0
SHD3_k127_1117123_4 esterase - - - 0.00000000000000000000000000000000000000000000000000000000006811 225.0
SHD3_k127_1117123_5 thiolester hydrolase activity K06889 - - 0.00000000000000002606 95.0
SHD3_k127_1146963_0 - - - - 0.0000000000000000000000006691 110.0
SHD3_k127_1146963_1 - - - - 0.00000001194 66.0
SHD3_k127_1164896_0 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 6.542e-208 660.0
SHD3_k127_1164896_1 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 423.0
SHD3_k127_1164896_2 coagulation factor 5 8 type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 344.0
SHD3_k127_1164896_3 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000001146 226.0
SHD3_k127_1164896_4 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000005006 91.0
SHD3_k127_1234624_0 Carboxypeptidase regulatory-like domain - - - 2.016e-228 742.0
SHD3_k127_1234624_1 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 407.0
SHD3_k127_1234624_2 Alg9-like mannosyltransferase family - - - 0.00000000006794 75.0
SHD3_k127_1234624_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000002948 64.0
SHD3_k127_123672_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 561.0
SHD3_k127_123672_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 346.0
SHD3_k127_123672_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 324.0
SHD3_k127_123672_3 Adenylate cyclase - - - 0.00000000000000001075 92.0
SHD3_k127_123672_4 FHA domain K07315 - 3.1.3.3 0.000000000002095 76.0
SHD3_k127_123672_5 Plasmid stabilization system K19092 - - 0.000002145 53.0
SHD3_k127_1267733_0 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 331.0
SHD3_k127_1267733_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003024 262.0
SHD3_k127_1267733_2 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000001975 158.0
SHD3_k127_1267733_3 Methionine biosynthesis protein MetW - - - 0.000000000000000000000006409 119.0
SHD3_k127_1267733_4 Acetyltransferase (GNAT) domain - - - 0.00000000000002817 87.0
SHD3_k127_1267733_5 Glycosyltransferases K16870 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0045226,GO:0046379,GO:0071704,GO:0071944,GO:1901576 2.4.1.289 0.0000000000001796 82.0
SHD3_k127_1267733_6 PFAM glycosyl transferase group 1 - - - 0.000000002425 69.0
SHD3_k127_1291953_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 546.0
SHD3_k127_1291953_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 538.0
SHD3_k127_1291953_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 342.0
SHD3_k127_1291953_3 O-methyltransferase activity - - - 0.00000000000000000000000000000000000004554 147.0
SHD3_k127_1291953_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000001968 129.0
SHD3_k127_1291953_5 NUDIX domain - - - 0.00000000000000000000000000008738 124.0
SHD3_k127_1303108_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 506.0
SHD3_k127_1303108_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 480.0
SHD3_k127_1303108_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001169 237.0
SHD3_k127_1303108_3 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000004432 151.0
SHD3_k127_1303108_4 Protein of unknown function, DUF255 - - - 0.00008835 54.0
SHD3_k127_1314708_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 542.0
SHD3_k127_1314708_1 biotin carboxylase activity K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 517.0
SHD3_k127_1314708_2 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 295.0
SHD3_k127_1314708_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000008773 220.0
SHD3_k127_1314708_4 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000204 188.0
SHD3_k127_1314708_5 ECF sigma factor K03088 - - 0.000000000000000000000000000000000003421 146.0
SHD3_k127_1314708_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000002877 136.0
SHD3_k127_1331016_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 356.0
SHD3_k127_1331016_1 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000000000009309 209.0
SHD3_k127_1336005_0 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 462.0
SHD3_k127_1336005_1 N,N-dimethylaniline monooxygenase activity K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 301.0
SHD3_k127_1336005_2 Tetratricopeptide repeat - - - 0.00005415 57.0
SHD3_k127_1359650_0 Belongs to the peptidase S8 family K14645,K20276 - - 0.00000000000000000000245 109.0
SHD3_k127_1359650_1 curli production assembly transport component CsgG - - - 0.00000000001047 76.0
SHD3_k127_1462030_0 Large extracellular alpha-helical protein - - - 0.0 1375.0
SHD3_k127_1462030_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000002006 198.0
SHD3_k127_1473215_0 RES - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001866 277.0
SHD3_k127_1473215_1 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000134 243.0
SHD3_k127_1473215_2 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000000000000000000000000000001338 184.0
SHD3_k127_1473215_3 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000002037 86.0
SHD3_k127_1473215_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000005522 59.0
SHD3_k127_1504359_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 406.0
SHD3_k127_1504359_1 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 367.0
SHD3_k127_1504359_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003097 258.0
SHD3_k127_1504359_3 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000000000000000000000001164 244.0
SHD3_k127_1504359_4 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000007548 226.0
SHD3_k127_1504359_5 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000001272 168.0
SHD3_k127_1504359_6 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000002446 168.0
SHD3_k127_1504359_7 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000003144 163.0
SHD3_k127_1515801_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 582.0
SHD3_k127_1515801_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 491.0
SHD3_k127_1515801_2 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 379.0
SHD3_k127_1515801_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 330.0
SHD3_k127_1515801_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003416 273.0
SHD3_k127_1515801_5 Protein of unknown function (DUF2400) K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000001228 218.0
SHD3_k127_1515801_6 Outer membrane protein beta-barrel family K16087,K16092 - - 0.000000000000000000000007128 118.0
SHD3_k127_1515801_7 Thioredoxin-like - - - 0.000000000000000000001816 109.0
SHD3_k127_1515801_8 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0009272 47.0
SHD3_k127_1535096_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 406.0
SHD3_k127_1535096_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 395.0
SHD3_k127_1535096_10 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000003196 129.0
SHD3_k127_1535096_11 Large extracellular alpha-helical protein K09607 - - 0.0000002039 65.0
SHD3_k127_1535096_12 COG3764 Sortase (surface protein transpeptidase) - - - 0.0005772 49.0
SHD3_k127_1535096_2 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 352.0
SHD3_k127_1535096_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 320.0
SHD3_k127_1535096_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001867 282.0
SHD3_k127_1535096_5 ABC transporter, permease protein K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002551 266.0
SHD3_k127_1535096_6 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000003737 250.0
SHD3_k127_1535096_7 COGs COG0110 Acetyltransferase (isoleucine patch superfamily) K00633 - 2.3.1.18 0.00000000000000000000000000000000000000000000000000000000000000000007372 239.0
SHD3_k127_1535096_8 pfam abc K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000004509 245.0
SHD3_k127_1535096_9 TIGRFAM YD repeat protein K21449 - - 0.0000000000000000000000000000000000000000000000000000000005334 230.0
SHD3_k127_154265_0 Involved in the tonB-independent uptake of proteins - - - 4.246e-224 722.0
SHD3_k127_154265_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 642.0
SHD3_k127_154265_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 509.0
SHD3_k127_154265_3 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 444.0
SHD3_k127_1549158_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 436.0
SHD3_k127_1549158_1 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000008528 237.0
SHD3_k127_1549158_2 Squalene/phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000002348 226.0
SHD3_k127_1549158_3 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000000000000000000000000000001044 196.0
SHD3_k127_1549158_4 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.000000000000000000000000000000000000007634 149.0
SHD3_k127_1549158_5 Phosphorylase superfamily K01243 - 3.2.2.9 0.000005314 57.0
SHD3_k127_1560519_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 362.0
SHD3_k127_1560519_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 364.0
SHD3_k127_1560519_10 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000002223 93.0
SHD3_k127_1560519_2 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 300.0
SHD3_k127_1560519_3 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000968 287.0
SHD3_k127_1560519_4 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000003853 206.0
SHD3_k127_1560519_5 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000002 184.0
SHD3_k127_1560519_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000002843 153.0
SHD3_k127_1560519_7 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000001745 139.0
SHD3_k127_1560519_8 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000001242 111.0
SHD3_k127_1560519_9 Phosphotransferase System K11189 - - 0.000000000000000000002486 101.0
SHD3_k127_1601499_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 461.0
SHD3_k127_1601499_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 377.0
SHD3_k127_1601499_2 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 318.0
SHD3_k127_1601499_3 Cytochrome c K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 296.0
SHD3_k127_1601499_4 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000003783 115.0
SHD3_k127_1601499_5 Sigma-54 interaction domain protein - - - 0.000002392 52.0
SHD3_k127_1622369_0 Involved in the tonB-independent uptake of proteins - - - 8.893e-219 707.0
SHD3_k127_1622369_1 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 362.0
SHD3_k127_1622369_2 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003216 264.0
SHD3_k127_1622369_3 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000001244 153.0
SHD3_k127_1622369_4 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000005131 152.0
SHD3_k127_1622369_5 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000002766 137.0
SHD3_k127_1622369_6 O-methyltransferase, family 2 - - - 0.000003141 53.0
SHD3_k127_1655451_0 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000001012 264.0
SHD3_k127_1655451_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000006647 142.0
SHD3_k127_1655451_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000001811 95.0
SHD3_k127_1655451_3 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000001234 78.0
SHD3_k127_171524_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 514.0
SHD3_k127_171524_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000006343 245.0
SHD3_k127_171524_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000001308 220.0
SHD3_k127_171524_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000001428 181.0
SHD3_k127_171524_4 DinB family - - - 0.000000000000000000000000000000000000004011 151.0
SHD3_k127_171524_5 PFAM YbbR family protein - - - 0.00000000000001881 82.0
SHD3_k127_1718358_0 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 589.0
SHD3_k127_1718358_1 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 547.0
SHD3_k127_1718358_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 340.0
SHD3_k127_1718358_3 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000004101 234.0
SHD3_k127_1718358_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000005457 169.0
SHD3_k127_1718358_5 Family of unknown function (DUF5329) - - - 0.00000000000000004198 87.0
SHD3_k127_1736307_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 340.0
SHD3_k127_1736307_1 - - - - 0.0000000000000000000000000000000000000000000000000000000001077 212.0
SHD3_k127_1736307_2 peptidase S8 and S53, subtilisin, kexin, sedolisin K08677 - - 0.000000000000000000000000000000000000000000001555 173.0
SHD3_k127_1740302_0 Peptidase family M13 K07386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 575.0
SHD3_k127_1743735_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 597.0
SHD3_k127_1743735_1 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000001939 219.0
SHD3_k127_1743735_2 Pyrophosphate-energized membrane proton pump K01507 GO:0000139,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005773,GO:0005794,GO:0005802,GO:0006810,GO:0008150,GO:0009678,GO:0012505,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0022804,GO:0022857,GO:0031090,GO:0031410,GO:0031982,GO:0031984,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0097708,GO:0098588,GO:0098791 3.6.1.1 0.000000000000000000004591 93.0
SHD3_k127_1756532_0 Dehydrogenase E1 component K11381 - 1.2.4.4 7.071e-306 949.0
SHD3_k127_1756532_1 Peptidase M15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006021 275.0
SHD3_k127_1756532_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000001519 211.0
SHD3_k127_1756532_3 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000123 209.0
SHD3_k127_1756532_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000002825 192.0
SHD3_k127_1756532_5 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000003667 165.0
SHD3_k127_1756532_6 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657,K18941 - - 0.0000000000000000000000000002023 132.0
SHD3_k127_1756532_7 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000002487 80.0
SHD3_k127_1756532_8 L,D-transpeptidase catalytic domain - - - 0.00000001997 65.0
SHD3_k127_1761756_0 Response regulator receiver - - - 1.864e-195 617.0
SHD3_k127_1761756_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 512.0
SHD3_k127_1761756_2 PRC-barrel domain - - - 0.000000000000000000000000000000000000000000111 162.0
SHD3_k127_1761756_4 SMART Rhodanese domain protein - - - 0.0000000533 54.0
SHD3_k127_1761756_5 PFAM UBA THIF-type NAD FAD binding K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0019344,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 0.000001232 53.0
SHD3_k127_1762863_0 Belongs to the ClpA ClpB family K03696 - - 7.433e-282 887.0
SHD3_k127_1762863_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 548.0
SHD3_k127_1762863_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000688 182.0
SHD3_k127_1762863_11 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000004936 150.0
SHD3_k127_1762863_12 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000004451 137.0
SHD3_k127_1762863_13 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000003991 127.0
SHD3_k127_1762863_14 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.00002636 58.0
SHD3_k127_1762863_15 outer membrane chaperone Skp (OmpH) K06142 - - 0.0001177 54.0
SHD3_k127_1762863_16 Domain of unknown function (DUF4149) - - - 0.0001619 49.0
SHD3_k127_1762863_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 350.0
SHD3_k127_1762863_3 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 317.0
SHD3_k127_1762863_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002928 289.0
SHD3_k127_1762863_5 Surface antigen variable number K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001213 299.0
SHD3_k127_1762863_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007653 272.0
SHD3_k127_1762863_7 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002481 270.0
SHD3_k127_1762863_8 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000001261 222.0
SHD3_k127_1762863_9 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000001418 200.0
SHD3_k127_1772134_0 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000306 218.0
SHD3_k127_1772134_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000779 234.0
SHD3_k127_1772134_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000001616 120.0
SHD3_k127_1788651_0 Transport of potassium into the cell K03549 - - 1.01e-205 659.0
SHD3_k127_1788651_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 441.0
SHD3_k127_1788651_2 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 441.0
SHD3_k127_1788651_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003342 240.0
SHD3_k127_1788651_4 PFAM Rieske 2Fe-2S domain protein K00479,K00499,K05708 - 1.14.12.19,1.14.15.7 0.00000000000000000000000000000000000000000000000000000000002308 213.0
SHD3_k127_1788651_5 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000001173 177.0
SHD3_k127_1788651_7 Subtilase family K13277 - - 0.00001837 53.0
SHD3_k127_179061_0 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000009432 216.0
SHD3_k127_179061_1 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000047 116.0
SHD3_k127_179061_2 - - - - 0.0000000000000000000000001271 120.0
SHD3_k127_183023_0 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005976 272.0
SHD3_k127_183023_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002924 270.0
SHD3_k127_183023_2 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000009078 217.0
SHD3_k127_183023_3 Sodium:solute symporter family K03307 - - 0.0000000000000000000000003961 120.0
SHD3_k127_183023_4 - - - - 0.00000000000000000000029 109.0
SHD3_k127_1868720_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 526.0
SHD3_k127_1868720_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000005919 229.0
SHD3_k127_1893394_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 514.0
SHD3_k127_1893394_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 444.0
SHD3_k127_1893394_2 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 356.0
SHD3_k127_1893394_3 Carboxypeptidase regulatory-like domain - - - 0.00000007846 66.0
SHD3_k127_1944841_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 497.0
SHD3_k127_1944841_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 417.0
SHD3_k127_1944841_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 394.0
SHD3_k127_1944841_3 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000002573 241.0
SHD3_k127_1944841_4 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000001491 130.0
SHD3_k127_1953671_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 612.0
SHD3_k127_1953671_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 358.0
SHD3_k127_1953671_2 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000006076 127.0
SHD3_k127_1953671_3 Glutathione peroxidase - - - 0.000000000000000000000008867 109.0
SHD3_k127_1953671_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000003171 109.0
SHD3_k127_1953671_5 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00001173 56.0
SHD3_k127_1953671_6 His Kinase A (phosphoacceptor) domain - - - 0.00006729 48.0
SHD3_k127_1958221_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 333.0
SHD3_k127_1958221_1 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 328.0
SHD3_k127_1958221_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000009313 134.0
SHD3_k127_1958221_3 - - - - 0.000000009407 68.0
SHD3_k127_1975126_0 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005441 248.0
SHD3_k127_1975126_1 Amino-transferase class IV K00824,K00826 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21,2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000008683 231.0
SHD3_k127_1975126_2 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000001607 216.0
SHD3_k127_1975126_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000005483 181.0
SHD3_k127_1975126_4 protein conserved in bacteria - - - 0.000000000000001473 85.0
SHD3_k127_1975126_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000008143 64.0
SHD3_k127_1975126_6 cobalamin-transporting ATPase activity - - - 0.000128 53.0
SHD3_k127_1989260_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 392.0
SHD3_k127_1989260_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000001072 191.0
SHD3_k127_1989260_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000004285 160.0
SHD3_k127_1989260_4 Tfp pilus assembly protein tip-associated adhesin PilY1 K02674 - - 0.0000000000000000000000000001707 134.0
SHD3_k127_1998227_0 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 304.0
SHD3_k127_1998227_1 Pyrroloquinoline quinone biosynthesis protein PqqB K06136 - - 0.000000000000000000000000000000000000006683 149.0
SHD3_k127_1998227_2 Protein of unknown function (DUF983) - - - 0.0000000000000002585 86.0
SHD3_k127_2024761_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 338.0
SHD3_k127_2024761_1 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000001338 177.0
SHD3_k127_2024761_2 extracellular solute-binding protein, family 5 K02035,K13893 - - 0.000000000000000000000000000000004146 140.0
SHD3_k127_2027276_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 391.0
SHD3_k127_2027276_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000013 273.0
SHD3_k127_2027276_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000003205 187.0
SHD3_k127_2027276_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000005909 177.0
SHD3_k127_2027276_4 structural constituent of ribosome K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001927 155.0
SHD3_k127_2027276_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000002413 137.0
SHD3_k127_2027276_6 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000009076 70.0
SHD3_k127_2027276_7 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000328 64.0
SHD3_k127_2027276_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001833 54.0
SHD3_k127_2108858_0 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 307.0
SHD3_k127_2108858_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000001169 237.0
SHD3_k127_2108858_2 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000001903 231.0
SHD3_k127_2108858_3 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000006457 185.0
SHD3_k127_2108858_4 Cytochrome c - - - 0.000000000000000000000000000000000112 141.0
SHD3_k127_2130680_0 L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 342.0
SHD3_k127_2130680_1 BMC - - - 0.00000000000000000000000000000000000000000000000000000000000000000001049 253.0
SHD3_k127_2130680_2 deoxyribose-phosphate aldolase activity K00852,K01619,K01840,K01844 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.1.15,4.1.2.4,5.4.2.8,5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000001929 252.0
SHD3_k127_2130680_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000008924 233.0
SHD3_k127_2130680_4 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000463 186.0
SHD3_k127_2130680_5 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000127 156.0
SHD3_k127_2130680_6 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000001208 147.0
SHD3_k127_2130680_7 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000001695 127.0
SHD3_k127_214184_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 378.0
SHD3_k127_214184_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 384.0
SHD3_k127_214184_2 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 369.0
SHD3_k127_214184_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 318.0
SHD3_k127_214184_4 Conserved hypothetical protein (DUF2461) - - - 0.0000000000001022 73.0
SHD3_k127_2155622_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005375 274.0
SHD3_k127_2155622_1 - - - - 0.000000000000000000000000000000000000000000000002211 177.0
SHD3_k127_2155622_2 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000006566 88.0
SHD3_k127_2155622_3 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000005295 81.0
SHD3_k127_2163033_0 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 484.0
SHD3_k127_2163033_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 332.0
SHD3_k127_2163033_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 314.0
SHD3_k127_2163033_3 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 294.0
SHD3_k127_2163033_4 Phosphoribosyl transferase domain - - - 0.00000000000000000000000001408 121.0
SHD3_k127_2163033_5 PFAM Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.00004046 47.0
SHD3_k127_2163033_6 Carboxypeptidase regulatory-like domain - - - 0.0001994 54.0
SHD3_k127_2164924_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 418.0
SHD3_k127_2164924_1 Semialdehyde dehydrogenase, NAD binding domain K00133,K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363 1.2.1.11,1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 362.0
SHD3_k127_2164924_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005438 285.0
SHD3_k127_2164924_3 Belongs to the DapB family K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000001644 167.0
SHD3_k127_2164924_4 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.0000000000000000000000000000000007108 143.0
SHD3_k127_2176352_0 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 375.0
SHD3_k127_2176352_1 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000001085 117.0
SHD3_k127_2176352_2 Regulatory protein, FmdB - - - 0.00000000000000008766 85.0
SHD3_k127_2176352_3 phosphorelay signal transduction system - - - 0.0000000264 63.0
SHD3_k127_2176352_4 XdhC and CoxI family K07402 - - 0.000000237 53.0
SHD3_k127_2189192_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 357.0
SHD3_k127_2189192_1 PFAM ABC transporter related K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 293.0
SHD3_k127_2189192_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003555 298.0
SHD3_k127_2189192_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000002129 137.0
SHD3_k127_2189192_4 lipopolysaccharide transport K09774 - - 0.00000000000001637 87.0
SHD3_k127_219123_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 421.0
SHD3_k127_219123_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005376 247.0
SHD3_k127_2202347_0 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 449.0
SHD3_k127_2202347_1 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 308.0
SHD3_k127_2202347_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000001177 114.0
SHD3_k127_2202347_3 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000001506 98.0
SHD3_k127_221967_0 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 299.0
SHD3_k127_221967_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000007888 138.0
SHD3_k127_221967_2 Pfam:UPF0118 - - - 0.000000000000000000000000000000002115 146.0
SHD3_k127_221967_3 chlorophyll binding - - - 0.0000000000000007404 91.0
SHD3_k127_221967_4 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.000000000000003307 83.0
SHD3_k127_22243_0 4Fe-4S single cluster domain K06937 - - 3.858e-240 757.0
SHD3_k127_22243_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 292.0
SHD3_k127_22243_10 SnoaL-like domain - - - 0.0000000000000000002156 104.0
SHD3_k127_22243_11 - - - - 0.000000000000000005772 94.0
SHD3_k127_22243_12 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000002329 86.0
SHD3_k127_22243_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001523 69.0
SHD3_k127_22243_14 - - - - 0.0000000002194 67.0
SHD3_k127_22243_15 positive regulation of growth rate - - - 0.00000001794 65.0
SHD3_k127_22243_16 PFAM helix-turn-helix, Fis-type - - - 0.00002681 51.0
SHD3_k127_22243_17 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0002277 51.0
SHD3_k127_22243_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 289.0
SHD3_k127_22243_3 PFAM Ribulose-phosphate 3-epimerase K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000004124 240.0
SHD3_k127_22243_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000003463 202.0
SHD3_k127_22243_5 - - - - 0.0000000000000000000000000000000000000000005666 177.0
SHD3_k127_22243_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000008797 162.0
SHD3_k127_22243_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000008363 149.0
SHD3_k127_22243_8 Choline/ethanolamine kinase K07102 - 2.7.1.221 0.0000000000000000000000003503 118.0
SHD3_k127_22243_9 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000006212 107.0
SHD3_k127_2227656_0 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 338.0
SHD3_k127_2227656_1 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004324 283.0
SHD3_k127_2227656_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000188 283.0
SHD3_k127_2227656_3 membrane - - - 0.000000000000000000000000000000000000007308 159.0
SHD3_k127_2227656_4 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000003495 89.0
SHD3_k127_2251660_0 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 410.0
SHD3_k127_2251660_1 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 381.0
SHD3_k127_2251660_2 COG2818 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000008455 258.0
SHD3_k127_2251660_3 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000149 240.0
SHD3_k127_2251660_4 Phosphoesterase family - - - 0.000000000000000000001648 101.0
SHD3_k127_2251660_5 - - - - 0.00000000006654 66.0
SHD3_k127_2251878_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 374.0
SHD3_k127_2251878_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000008107 237.0
SHD3_k127_2251878_2 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000001683 137.0
SHD3_k127_2251878_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000008945 137.0
SHD3_k127_2251878_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000291 113.0
SHD3_k127_2251878_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000005633 107.0
SHD3_k127_2251878_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000005158 88.0
SHD3_k127_2294936_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 517.0
SHD3_k127_2294936_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 377.0
SHD3_k127_2294936_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000003907 184.0
SHD3_k127_2294936_3 integral membrane protein - - - 0.0004125 51.0
SHD3_k127_2305093_0 ERAP1-like C-terminal domain K01263 - 3.4.11.14 9.609e-228 730.0
SHD3_k127_2305093_1 Protein kinase domain K12132 - 2.7.11.1 2.548e-218 698.0
SHD3_k127_2309993_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 1.394e-272 849.0
SHD3_k127_2309993_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000002602 134.0
SHD3_k127_2309993_2 Tetratricopeptide repeat - - - 0.000000000000000000000000275 118.0
SHD3_k127_2330517_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 580.0
SHD3_k127_2330517_1 Dihydroxyacetone kinase family K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 422.0
SHD3_k127_2330517_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000003402 235.0
SHD3_k127_2330517_3 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000005356 189.0
SHD3_k127_2330517_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000003344 187.0
SHD3_k127_2330517_5 - - - - 0.000002447 60.0
SHD3_k127_2330735_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 2.084e-237 743.0
SHD3_k127_2330735_1 Malate synthase K01638 - 2.3.3.9 3.675e-233 732.0
SHD3_k127_2330735_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 537.0
SHD3_k127_2330735_3 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 476.0
SHD3_k127_2330735_4 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 389.0
SHD3_k127_2330735_5 ABC transporter K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 316.0
SHD3_k127_2330735_6 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000002036 259.0
SHD3_k127_2330735_7 - - - - 0.0000000006242 67.0
SHD3_k127_2333373_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 378.0
SHD3_k127_2333373_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000005571 226.0
SHD3_k127_2333373_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000003064 83.0
SHD3_k127_2389593_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 487.0
SHD3_k127_2389593_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 444.0
SHD3_k127_2389593_10 Protein of unknown function (DUF1566) - - - 0.0000000000000002993 89.0
SHD3_k127_2389593_11 - - - - 0.000000000008029 76.0
SHD3_k127_2389593_2 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 386.0
SHD3_k127_2389593_3 LAO AO transport system K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 336.0
SHD3_k127_2389593_4 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000009335 194.0
SHD3_k127_2389593_5 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000002644 207.0
SHD3_k127_2389593_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000005252 166.0
SHD3_k127_2389593_7 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000000002461 153.0
SHD3_k127_2389593_8 - - - - 0.0000000000000000000001162 103.0
SHD3_k127_2389593_9 Lipoprotein releasing system transmembrane protein K09808 - - 0.00000000000000002521 89.0
SHD3_k127_2407771_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.06e-213 676.0
SHD3_k127_2407771_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000003151 205.0
SHD3_k127_2407771_2 positive regulation of proteasomal protein catabolic process - - - 0.0000000000000000000000000000000000000000000001123 191.0
SHD3_k127_2407771_3 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000653 68.0
SHD3_k127_2417747_0 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 535.0
SHD3_k127_2417747_1 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 485.0
SHD3_k127_2417747_10 Domain of unknown function (DUF4439) - - - 0.0000000000000000000000000000006303 128.0
SHD3_k127_2417747_11 Smr domain - - - 0.000000000000000000000000004955 111.0
SHD3_k127_2417747_12 Anti-sigma-K factor rskA - - - 0.0000000000000000000003332 106.0
SHD3_k127_2417747_13 diguanylate cyclase - - - 0.0000000000000000002151 101.0
SHD3_k127_2417747_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 497.0
SHD3_k127_2417747_3 PFAM Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 302.0
SHD3_k127_2417747_4 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004743 286.0
SHD3_k127_2417747_5 glycine betaine K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005333 262.0
SHD3_k127_2417747_6 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000004145 244.0
SHD3_k127_2417747_7 Domain of unknown function (DUF4331) - - - 0.000000000000000000000000000000000000000000000000000000000000000003451 246.0
SHD3_k127_2417747_8 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000005905 186.0
SHD3_k127_2417747_9 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000001284 154.0
SHD3_k127_2420407_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 1.064e-295 933.0
SHD3_k127_2420407_1 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000006893 184.0
SHD3_k127_2420407_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000511 127.0
SHD3_k127_2420407_3 Winged helix DNA-binding domain - - - 0.00000007713 60.0
SHD3_k127_2421157_0 oxidoreductase activity K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 367.0
SHD3_k127_2421157_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 304.0
SHD3_k127_2421157_2 Protein of unknown function with PCYCGC motif - - - 0.0000003273 61.0
SHD3_k127_2421157_3 Glycosyl transferase 4-like domain - - - 0.000009522 52.0
SHD3_k127_2421381_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 392.0
SHD3_k127_2421381_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 334.0
SHD3_k127_2421381_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 322.0
SHD3_k127_2421381_3 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
SHD3_k127_2421381_4 Glycosyl transferase family 2 K09931 - - 0.0000000000000000000000000000000000000001132 163.0
SHD3_k127_2421381_5 Molybdenum cofactor biosynthesis protein B - - - 0.000000000000000000000000000000000000008186 150.0
SHD3_k127_2421381_6 MoaC family K03637 - 4.6.1.17 0.0000000000000000000000000000000000001943 155.0
SHD3_k127_2421381_7 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000001006 121.0
SHD3_k127_2421381_8 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000002608 109.0
SHD3_k127_2421381_9 transferase activity, transferring acyl groups - - - 0.0006609 49.0
SHD3_k127_2433443_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.565e-244 774.0
SHD3_k127_2433443_1 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 404.0
SHD3_k127_2433443_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 333.0
SHD3_k127_2433443_3 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006823 287.0
SHD3_k127_2433443_4 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004061 249.0
SHD3_k127_2433443_5 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000002717 188.0
SHD3_k127_2433443_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000002952 184.0
SHD3_k127_2433443_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000082 179.0
SHD3_k127_2433443_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000001315 141.0
SHD3_k127_2433443_9 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000001536 91.0
SHD3_k127_244527_0 PFAM BNR Asp-box repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 578.0
SHD3_k127_244527_1 receptor K02014 - - 0.00000000000000000000000001386 127.0
SHD3_k127_244527_2 Domain of unknown function (DUF1330) - - - 0.00000000000000000000766 108.0
SHD3_k127_2477398_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.017e-203 662.0
SHD3_k127_2477398_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 533.0
SHD3_k127_2477398_10 Yqey-like protein K09117 - - 0.00000000000000000000000002095 115.0
SHD3_k127_2477398_11 CYTH K05873 - 4.6.1.1 0.00000000000000000000000007809 119.0
SHD3_k127_2477398_12 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000003304 91.0
SHD3_k127_2477398_13 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000005716 93.0
SHD3_k127_2477398_14 C4-type zinc ribbon domain K07164 - - 0.0000000000000001971 88.0
SHD3_k127_2477398_15 PFAM DivIVA family protein K04074 - - 0.0000000000005984 79.0
SHD3_k127_2477398_16 domain, Protein K03407 - 2.7.13.3 0.00005111 55.0
SHD3_k127_2477398_2 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 444.0
SHD3_k127_2477398_3 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 369.0
SHD3_k127_2477398_4 ATPase domain of DNA mismatch repair MUTS family K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 367.0
SHD3_k127_2477398_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 348.0
SHD3_k127_2477398_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000004881 216.0
SHD3_k127_2477398_7 PFAM Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000004455 147.0
SHD3_k127_2477398_8 cyclohydrolase K01746 - 4.3.1.4 0.00000000000000000000000000000003582 134.0
SHD3_k127_2477398_9 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.000000000000000000000000000003482 128.0
SHD3_k127_2514774_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 550.0
SHD3_k127_2514774_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 509.0
SHD3_k127_2514774_2 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 288.0
SHD3_k127_2514774_3 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000683 286.0
SHD3_k127_2514774_4 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000693 228.0
SHD3_k127_2514774_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000001395 113.0
SHD3_k127_2540360_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 7.008e-194 636.0
SHD3_k127_2540360_1 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000002352 182.0
SHD3_k127_2540360_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00000000000000000000000000000004946 139.0
SHD3_k127_2540360_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000001525 128.0
SHD3_k127_2540752_0 Zinc-uptake complex component A periplasmic K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 357.0
SHD3_k127_2540752_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 322.0
SHD3_k127_2540752_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001423 294.0
SHD3_k127_2540752_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006096 271.0
SHD3_k127_2540752_4 Thioredoxin K03671 - - 0.00000000000000000000000000000000000003381 145.0
SHD3_k127_2540752_5 Pfam Cation efflux - - - 0.0000000000000000004015 95.0
SHD3_k127_2540752_6 ABC 3 transport family K02075 - - 0.000000001522 68.0
SHD3_k127_2540752_7 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000005085 57.0
SHD3_k127_2548408_0 modulates the activities of several proteins which are inactive in their K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005143 256.0
SHD3_k127_2548408_1 PFAM Fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001277 258.0
SHD3_k127_2548408_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000001315 207.0
SHD3_k127_2548408_3 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.000000000000000000000000000000000000000000001658 171.0
SHD3_k127_2548408_4 - - - - 0.000000000000000000000000000002568 130.0
SHD3_k127_2548408_5 PFAM ABC transporter related K01990 - - 0.00000000000000000001328 93.0
SHD3_k127_2548408_6 COG COG0845 Membrane-fusion protein K01993 - - 0.00000001319 66.0
SHD3_k127_255052_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 527.0
SHD3_k127_255052_1 Proline dehydrogenase K00318 - - 0.00000000000000000005934 90.0
SHD3_k127_2666344_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1142.0
SHD3_k127_2666344_1 PFAM aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 388.0
SHD3_k127_2666344_2 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 391.0
SHD3_k127_2666344_3 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 337.0
SHD3_k127_2666344_5 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000003928 151.0
SHD3_k127_271448_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 552.0
SHD3_k127_271448_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 520.0
SHD3_k127_271448_2 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000093 272.0
SHD3_k127_271448_3 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000001638 256.0
SHD3_k127_271448_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000004242 211.0
SHD3_k127_271448_5 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000004349 130.0
SHD3_k127_271448_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000004152 66.0
SHD3_k127_271448_8 - - - - 0.0001471 53.0
SHD3_k127_272622_0 iron-sulfur cluster assembly K07400 - - 0.0000000000000000000000000000000000000003187 168.0
SHD3_k127_272622_1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.00000000000000000003071 91.0
SHD3_k127_2736261_0 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 414.0
SHD3_k127_2736261_1 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 331.0
SHD3_k127_2736261_2 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 320.0
SHD3_k127_2736261_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 318.0
SHD3_k127_2736261_4 - K07018 - - 0.000000000000000000000000000000000000000003788 165.0
SHD3_k127_2736261_5 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000002227 165.0
SHD3_k127_2736261_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000001964 144.0
SHD3_k127_2744304_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 567.0
SHD3_k127_2744304_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 325.0
SHD3_k127_2744304_2 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000006226 168.0
SHD3_k127_2825330_0 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 400.0
SHD3_k127_2825330_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000001933 211.0
SHD3_k127_2825330_2 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000001559 181.0
SHD3_k127_2825330_3 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000004411 136.0
SHD3_k127_2825330_4 AhpC/TSA family - - - 0.0000000000000000000000000000000004482 150.0
SHD3_k127_2840732_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 477.0
SHD3_k127_2840732_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 302.0
SHD3_k127_2840732_2 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000001168 244.0
SHD3_k127_2840732_3 Phenylacetate-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000002663 184.0
SHD3_k127_2840732_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000001769 140.0
SHD3_k127_2840732_5 Uncharacterised protein family (UPF0158) - - - 0.0000000002128 67.0
SHD3_k127_2840732_6 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.000000001 63.0
SHD3_k127_2840732_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000005951 60.0
SHD3_k127_2862532_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 354.0
SHD3_k127_2862532_1 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000001519 219.0
SHD3_k127_2862532_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000001252 150.0
SHD3_k127_2862532_3 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000006602 128.0
SHD3_k127_2862532_4 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000002467 131.0
SHD3_k127_2862532_5 Transcriptional regulatory protein, C terminal K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000007958 86.0
SHD3_k127_2862532_6 Thioesterase-like superfamily K07107 - - 0.000000000000004077 89.0
SHD3_k127_2862532_7 Transcriptional regulator - - - 0.00005936 47.0
SHD3_k127_2864086_1 Domain of unknown function (DUF1858) - - - 0.000000000000000000000000000000000000612 160.0
SHD3_k127_2868036_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 3.498e-220 713.0
SHD3_k127_2868036_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 494.0
SHD3_k127_2868036_2 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000000000000000001439 231.0
SHD3_k127_2868036_3 DinB family - - - 0.00001921 53.0
SHD3_k127_2935388_0 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 367.0
SHD3_k127_2935388_1 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 361.0
SHD3_k127_2935388_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 331.0
SHD3_k127_2935388_3 synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 295.0
SHD3_k127_2935388_4 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001809 294.0
SHD3_k127_2935388_5 aminopeptidase activity K07004 - - 0.0000000000000000000000000000000000000000000000000000000007301 229.0
SHD3_k127_2935388_6 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000534 159.0
SHD3_k127_2935388_7 Transglycosylase SLT domain - - - 0.000000000000000000000000000000007538 137.0
SHD3_k127_2935388_8 YXWGXW repeat (2 copies) - - - 0.00000000000000000000564 98.0
SHD3_k127_2959831_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 6.859e-302 947.0
SHD3_k127_2959831_1 Succinyl-CoA ligase like flavodoxin domain - - - 1.314e-240 771.0
SHD3_k127_2959831_10 Universal stress protein family - - - 0.000002317 55.0
SHD3_k127_2959831_11 Family of unknown function (DUF5335) - - - 0.00003972 53.0
SHD3_k127_2959831_12 Belongs to the universal stress protein A family - - - 0.00005727 54.0
SHD3_k127_2959831_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 600.0
SHD3_k127_2959831_3 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008241 259.0
SHD3_k127_2959831_4 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000001198 240.0
SHD3_k127_2959831_5 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000005907 128.0
SHD3_k127_2959831_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000008142 98.0
SHD3_k127_2959831_7 bacterial OsmY and nodulation domain - - - 0.0000000000000004419 85.0
SHD3_k127_2959831_8 IMP dehydrogenase activity - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.0000000000000009198 85.0
SHD3_k127_2959831_9 belongs to the carbohydrate kinase PfkB family K00917,K16370 - 2.7.1.11,2.7.1.144 0.000000000000009172 85.0
SHD3_k127_2962887_0 Involved in the tonB-independent uptake of proteins - - - 8.442e-222 721.0
SHD3_k127_2962887_1 - - - - 0.00000000000000000000000000000000000000000001385 167.0
SHD3_k127_2962887_2 cAMP biosynthetic process - - - 0.00000000000000000007025 100.0
SHD3_k127_2969374_0 Flotillin K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 309.0
SHD3_k127_2969374_1 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008203 274.0
SHD3_k127_2969374_2 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000000000336 151.0
SHD3_k127_2969374_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000001967 147.0
SHD3_k127_2969374_4 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000008716 76.0
SHD3_k127_2994941_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 314.0
SHD3_k127_2994941_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000009921 191.0
SHD3_k127_2994941_2 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000001204 179.0
SHD3_k127_2994941_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000001338 188.0
SHD3_k127_2994941_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000004556 145.0
SHD3_k127_2994941_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000004749 142.0
SHD3_k127_2994941_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000001599 110.0
SHD3_k127_3001886_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 339.0
SHD3_k127_3001886_1 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 302.0
SHD3_k127_3001886_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 307.0
SHD3_k127_3001886_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000008845 235.0
SHD3_k127_3001886_4 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000007294 199.0
SHD3_k127_3001886_5 SMART Metal-dependent phosphohydrolase, HD region K07141 - 2.7.7.76 0.000000000000000000000000005997 123.0
SHD3_k127_3001886_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000003962 96.0
SHD3_k127_3001886_7 Transcriptional regulator PadR-like family - - - 0.000000000000001526 83.0
SHD3_k127_3001900_0 coagulation factor 5 8 type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 586.0
SHD3_k127_3001900_1 ABC transporter substrate-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 456.0
SHD3_k127_3001900_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 376.0
SHD3_k127_3001900_3 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 348.0
SHD3_k127_3001900_4 Binding-protein-dependent transport system inner membrane component K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 328.0
SHD3_k127_3005497_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 4.274e-212 667.0
SHD3_k127_3005497_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 505.0
SHD3_k127_3005497_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 429.0
SHD3_k127_3005497_3 Cardiolipin synthetase K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 368.0
SHD3_k127_3005497_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000003201 259.0
SHD3_k127_3005497_5 DNA polymerase III subunit epsilon K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000004218 239.0
SHD3_k127_3005497_6 WYL domain K13572 - - 0.000000000000000000000000000000000000000000009791 177.0
SHD3_k127_3005497_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000001316 121.0
SHD3_k127_3005497_8 cell redox homeostasis - - - 0.0000000000000000000002858 104.0
SHD3_k127_3005497_9 Redoxin - - - 0.00000002654 56.0
SHD3_k127_3009264_0 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003852 302.0
SHD3_k127_3009264_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000001376 198.0
SHD3_k127_3009264_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000002641 168.0
SHD3_k127_3046860_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008906 542.0
SHD3_k127_3046860_1 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 448.0
SHD3_k127_3046860_10 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000006229 113.0
SHD3_k127_3046860_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 332.0
SHD3_k127_3046860_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 312.0
SHD3_k127_3046860_4 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000005805 224.0
SHD3_k127_3046860_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000002651 216.0
SHD3_k127_3046860_6 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000000002616 189.0
SHD3_k127_3046860_7 PFAM ABC transporter related K02193 - 3.6.3.41 0.00000000000000000000000000000000000000001407 160.0
SHD3_k127_3046860_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000001263 162.0
SHD3_k127_3046860_9 CcmB protein K02194 - - 0.00000000000000000000000000000003658 138.0
SHD3_k127_3066950_0 Outer membrane receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 627.0
SHD3_k127_3066950_1 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 336.0
SHD3_k127_3066950_2 LacI family K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 338.0
SHD3_k127_3066950_3 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
SHD3_k127_3066950_4 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000001001 211.0
SHD3_k127_3066950_5 - - - - 0.0000000000000007282 83.0
SHD3_k127_3066950_6 Putative porin - - - 0.0002575 49.0
SHD3_k127_3081953_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1869.0
SHD3_k127_3100827_0 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 331.0
SHD3_k127_3100827_1 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 324.0
SHD3_k127_3100827_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001066 223.0
SHD3_k127_3100827_3 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000001906 164.0
SHD3_k127_3100827_4 nucleoside triphosphate catabolic process K01776,K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66,5.1.1.3 0.0002294 44.0
SHD3_k127_3104215_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 508.0
SHD3_k127_3104215_1 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 464.0
SHD3_k127_3104215_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 371.0
SHD3_k127_3104215_3 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004917 270.0
SHD3_k127_3104215_4 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000003488 112.0
SHD3_k127_3110523_0 chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 467.0
SHD3_k127_3110523_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 450.0
SHD3_k127_3110523_10 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000001135 56.0
SHD3_k127_3110523_2 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000002259 197.0
SHD3_k127_3110523_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000001126 180.0
SHD3_k127_3110523_4 cytochrome - - - 0.000000000000000000000000000000000000000009086 167.0
SHD3_k127_3110523_5 AhpC/TSA family - - - 0.00000000000000000000000000000000001907 149.0
SHD3_k127_3110523_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000146 149.0
SHD3_k127_3110523_7 MerR, DNA binding - - - 0.000000000000000000000000000008079 128.0
SHD3_k127_3110523_9 Winged helix DNA-binding domain - - - 0.000000000000000000000004924 111.0
SHD3_k127_3127303_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 473.0
SHD3_k127_3127303_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 405.0
SHD3_k127_3127303_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 376.0
SHD3_k127_3127303_3 PFAM Major facilitator superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 359.0
SHD3_k127_3127303_4 abc transporter, ATP-binding protein K01995,K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 357.0
SHD3_k127_3127303_5 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002784 280.0
SHD3_k127_3127303_6 MFS/sugar transport protein K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009122 272.0
SHD3_k127_3127303_7 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009626 261.0
SHD3_k127_3127303_8 L-phenylalanine transmembrane transporter activity K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000001071 247.0
SHD3_k127_3127303_9 Lipocalin-like domain - - - 0.0000000000000000005468 95.0
SHD3_k127_3145178_0 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 316.0
SHD3_k127_3145178_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 328.0
SHD3_k127_3145178_2 AI-2E family transporter - - - 0.0000000000000000000000000000003423 139.0
SHD3_k127_3145178_3 - - - - 0.000000000000543 70.0
SHD3_k127_3151645_0 ABC transporter K06020 - 3.6.3.25 3.477e-262 817.0
SHD3_k127_3151645_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.472e-228 724.0
SHD3_k127_3151645_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000003712 191.0
SHD3_k127_3151645_12 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000000000003357 113.0
SHD3_k127_3151645_13 Serine aminopeptidase, S33 - - - 0.000000000005048 76.0
SHD3_k127_3151645_14 Forkhead associated domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.000004233 58.0
SHD3_k127_3151645_2 B12 binding domain - - - 3.009e-222 699.0
SHD3_k127_3151645_3 IgA Peptidase M64 - - - 3.992e-215 676.0
SHD3_k127_3151645_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 481.0
SHD3_k127_3151645_5 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003983 293.0
SHD3_k127_3151645_6 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006272 259.0
SHD3_k127_3151645_7 Pyrroloquinoline quinone biosynthesis protein PqqB K06136 - - 0.0000000000000000000000000000000000000000000000000000000000001005 220.0
SHD3_k127_3151645_8 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000004826 213.0
SHD3_k127_3151645_9 - - - - 0.00000000000000000000000000000000000000000000000000000000006706 210.0
SHD3_k127_3172530_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.08e-263 844.0
SHD3_k127_3172530_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 434.0
SHD3_k127_3172530_2 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000001216 139.0
SHD3_k127_3174134_0 Protein tyrosine kinase K12132 - 2.7.11.1 1.946e-207 679.0
SHD3_k127_3174134_1 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.000000014 69.0
SHD3_k127_3174134_2 - - - - 0.0007259 45.0
SHD3_k127_3251945_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 435.0
SHD3_k127_3251945_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000002863 190.0
SHD3_k127_3251945_2 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000119 114.0
SHD3_k127_3251945_3 GAF domain K01768 - 4.6.1.1 0.00000000000000007017 91.0
SHD3_k127_3251945_4 Belongs to the EPSP synthase family. MurA subfamily K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.0000003431 52.0
SHD3_k127_3292181_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 362.0
SHD3_k127_3292181_1 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000061 218.0
SHD3_k127_3292181_2 His Kinase A (phosphoacceptor) domain K07768 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 0.00000000493 66.0
SHD3_k127_3292181_3 - - - - 0.00002785 54.0
SHD3_k127_3357167_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 7.677e-204 657.0
SHD3_k127_3357167_1 Domain of unknown function (DUF3536) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 566.0
SHD3_k127_3357167_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 546.0
SHD3_k127_3357167_3 Arginosuccinate synthase K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 390.0
SHD3_k127_3360057_0 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 497.0
SHD3_k127_3360057_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 387.0
SHD3_k127_3360057_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 359.0
SHD3_k127_3360057_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 303.0
SHD3_k127_3360057_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000004387 185.0
SHD3_k127_3360057_5 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000001437 79.0
SHD3_k127_338552_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 612.0
SHD3_k127_338552_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 460.0
SHD3_k127_338552_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000008864 154.0
SHD3_k127_338552_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000003221 128.0
SHD3_k127_338552_12 histone H2A K63-linked ubiquitination K10914 - - 0.00000000000000000000000000009662 132.0
SHD3_k127_338552_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000001651 108.0
SHD3_k127_338552_14 Iron-sulfur cluster-binding domain - - - 0.000000000000000007442 97.0
SHD3_k127_338552_15 - - - - 0.000000000000001953 83.0
SHD3_k127_338552_16 - - - - 0.00000001648 68.0
SHD3_k127_338552_18 HEAT repeats - - - 0.00006023 55.0
SHD3_k127_338552_2 asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004516 291.0
SHD3_k127_338552_3 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000004312 217.0
SHD3_k127_338552_4 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000005857 223.0
SHD3_k127_338552_5 carboxypeptidase activity K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000004213 201.0
SHD3_k127_338552_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000001401 195.0
SHD3_k127_338552_7 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000001583 175.0
SHD3_k127_338552_8 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000000000006518 165.0
SHD3_k127_338552_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000001357 168.0
SHD3_k127_345573_0 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 584.0
SHD3_k127_345573_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 484.0
SHD3_k127_345573_10 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000001947 207.0
SHD3_k127_345573_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000001522 187.0
SHD3_k127_345573_12 antisigma factor binding - - - 0.00000000000000000000001327 106.0
SHD3_k127_345573_13 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000001329 104.0
SHD3_k127_345573_14 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.0000000000000000917 96.0
SHD3_k127_345573_2 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 367.0
SHD3_k127_345573_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 364.0
SHD3_k127_345573_4 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 377.0
SHD3_k127_345573_5 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 295.0
SHD3_k127_345573_6 Sigma-54 interaction domain K02584,K07713,K15836,K21009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001383 294.0
SHD3_k127_345573_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000002106 259.0
SHD3_k127_345573_8 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000001226 229.0
SHD3_k127_345573_9 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000001125 214.0
SHD3_k127_354173_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1022.0
SHD3_k127_354173_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009584 551.0
SHD3_k127_354173_10 PFAM Glycosyl transferase family 2 - - - 0.000001135 61.0
SHD3_k127_354173_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 465.0
SHD3_k127_354173_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 376.0
SHD3_k127_354173_4 Major facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 356.0
SHD3_k127_354173_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 346.0
SHD3_k127_354173_6 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 320.0
SHD3_k127_354173_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000003007 106.0
SHD3_k127_354173_8 Glycosyl transferase family group 2 - - - 0.0000000000000000003417 99.0
SHD3_k127_354173_9 Glycosyltransferase like family 2 - - - 0.00000000000000006251 95.0
SHD3_k127_355518_0 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000003519 240.0
SHD3_k127_355518_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000002876 161.0
SHD3_k127_355518_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000002838 104.0
SHD3_k127_355518_3 polysaccharide deacetylase - - - 0.0000000000008255 72.0
SHD3_k127_355518_4 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.000000244 61.0
SHD3_k127_355518_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0002896 45.0
SHD3_k127_3578936_0 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 478.0
SHD3_k127_3578936_1 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 385.0
SHD3_k127_3578936_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000006782 209.0
SHD3_k127_3578936_3 PFAM Formiminotransferase domain K00603 - 2.1.2.5 0.000000000000000000000000000000000001449 139.0
SHD3_k127_3578936_4 - - - - 0.00000000000000000000000000006614 125.0
SHD3_k127_3578936_5 Lysin motif - - - 0.00000000000000000001614 94.0
SHD3_k127_3588692_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 5.888e-196 625.0
SHD3_k127_3588692_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002233 274.0
SHD3_k127_3596510_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.0 1038.0
SHD3_k127_3596510_1 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 507.0
SHD3_k127_3596510_10 Iron-binding zinc finger CDGSH type K05710 - - 0.0000000000000000000001063 100.0
SHD3_k127_3596510_11 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000003366 87.0
SHD3_k127_3596510_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 454.0
SHD3_k127_3596510_3 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 432.0
SHD3_k127_3596510_4 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 358.0
SHD3_k127_3596510_5 2Fe-2S -binding K13483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000185 248.0
SHD3_k127_3596510_6 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000001162 222.0
SHD3_k127_3596510_7 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000206 205.0
SHD3_k127_3596510_8 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000007605 170.0
SHD3_k127_3596510_9 DinB family - - - 0.00000000000000000000000000000000253 149.0
SHD3_k127_3626725_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.931e-278 885.0
SHD3_k127_3626725_1 S4 RNA-binding domain K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000001885 271.0
SHD3_k127_3626725_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000006664 228.0
SHD3_k127_3626725_3 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.0000000000000000000000000000005852 137.0
SHD3_k127_3626725_4 Mechanosensitive ion channel - - - 0.00000000000000000000000000243 121.0
SHD3_k127_3626725_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000001414 107.0
SHD3_k127_36440_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1317.0
SHD3_k127_36440_1 Cytochrome b/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 302.0
SHD3_k127_36440_2 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003778 275.0
SHD3_k127_3648911_0 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 508.0
SHD3_k127_3648911_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 480.0
SHD3_k127_3648911_2 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 382.0
SHD3_k127_3648911_3 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 335.0
SHD3_k127_3648911_4 Formyl transferase K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007583 287.0
SHD3_k127_3648911_5 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000003875 205.0
SHD3_k127_3648911_6 Transport permease protein K09688,K09690 - - 0.000000000000000000000000000000000000006717 155.0
SHD3_k127_3648911_7 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000000001329 126.0
SHD3_k127_3663870_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 475.0
SHD3_k127_3663870_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 450.0
SHD3_k127_3663870_2 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 376.0
SHD3_k127_3663870_3 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000001147 114.0
SHD3_k127_3663870_4 amine dehydrogenase activity K21449 - - 0.000000000000000000000003326 114.0
SHD3_k127_3663870_5 Domain of unknown function (DUF4437) - - - 0.000000000000000000008426 104.0
SHD3_k127_3663870_6 self proteolysis - - - 0.00000000000944 78.0
SHD3_k127_3668744_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 3.568e-253 813.0
SHD3_k127_3668744_1 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 531.0
SHD3_k127_3668744_10 O-Antigen ligase - - - 0.00003851 56.0
SHD3_k127_3668744_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 300.0
SHD3_k127_3668744_3 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000861 266.0
SHD3_k127_3668744_4 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000003493 214.0
SHD3_k127_3668744_5 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K20997 - - 0.000000000000000000000000000000000000000000000000000000007848 216.0
SHD3_k127_3668744_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000001071 174.0
SHD3_k127_3668744_7 Glycosyl transferases group 1 K00786 - - 0.00000000000000000000000000000000001593 143.0
SHD3_k127_3668744_8 -transport system K01992 - - 0.0000000000142 76.0
SHD3_k127_3668744_9 Thioredoxin-like - - - 0.00000001652 67.0
SHD3_k127_3687240_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 598.0
SHD3_k127_3687240_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 554.0
SHD3_k127_3687240_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 394.0
SHD3_k127_3687240_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 332.0
SHD3_k127_3687999_0 Heat shock 70 kDa protein K04043 - - 9.456e-231 729.0
SHD3_k127_3687999_1 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 355.0
SHD3_k127_3687999_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000002974 236.0
SHD3_k127_3687999_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009628,GO:0009986,GO:0009987,GO:0009991,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030246,GO:0030247,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071496,GO:0071840,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000001922 119.0
SHD3_k127_3687999_4 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000496 112.0
SHD3_k127_3687999_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000005315 103.0
SHD3_k127_3687999_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000001602 57.0
SHD3_k127_3687999_7 Domain of unknown function (DUF2520) - - - 0.00000002596 62.0
SHD3_k127_3698707_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.735e-246 789.0
SHD3_k127_3698707_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000002585 250.0
SHD3_k127_3698707_10 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000225 119.0
SHD3_k127_3698707_11 RNA recognition motif - - - 0.00000000000000000000000007575 110.0
SHD3_k127_3698707_12 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000001919 111.0
SHD3_k127_3698707_13 Thioesterase-like superfamily K07107 - - 0.0000000000000005843 85.0
SHD3_k127_3698707_14 SnoaL-like polyketide cyclase - - - 0.00001663 48.0
SHD3_k127_3698707_2 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000007125 218.0
SHD3_k127_3698707_3 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000001683 164.0
SHD3_k127_3698707_4 DinB family - - - 0.00000000000000000000000000000000000000005134 160.0
SHD3_k127_3698707_5 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000003205 155.0
SHD3_k127_3698707_6 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000007099 158.0
SHD3_k127_3698707_7 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000055 136.0
SHD3_k127_3698707_8 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000000000007887 129.0
SHD3_k127_3698707_9 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000000000001882 128.0
SHD3_k127_3725683_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 349.0
SHD3_k127_3725683_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000002118 142.0
SHD3_k127_3725683_2 peptidyl-tyrosine sulfation - - - 0.000000000000000008355 98.0
SHD3_k127_3725683_3 Domain of unknown function (DUF1844) - - - 0.00000001557 57.0
SHD3_k127_3758951_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 416.0
SHD3_k127_3758951_1 cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 394.0
SHD3_k127_3758951_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K18286 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4,3.5.4.40 0.00000000000000000000000000000000000000000000000002622 192.0
SHD3_k127_3758951_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000006211 186.0
SHD3_k127_3758951_4 Haemolytic K08998 - - 0.0000000000000000002839 91.0
SHD3_k127_3758951_5 Preprotein translocase SecG subunit K03075 - - 0.00000000000005248 78.0
SHD3_k127_3758951_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000001528 68.0
SHD3_k127_3758951_7 Putative adhesin - - - 0.00003328 55.0
SHD3_k127_3758951_8 response to antibiotic - - - 0.0005378 48.0
SHD3_k127_3759930_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 424.0
SHD3_k127_3759930_1 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 409.0
SHD3_k127_3759930_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 407.0
SHD3_k127_3759930_3 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 359.0
SHD3_k127_3759930_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 289.0
SHD3_k127_3759930_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000001255 221.0
SHD3_k127_3759930_6 - - - - 0.000000000000000000000000000000000000127 148.0
SHD3_k127_3759930_7 TM2 domain - - - 0.0000000000000000000000006057 105.0
SHD3_k127_3771729_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 595.0
SHD3_k127_3771729_1 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 474.0
SHD3_k127_3771729_2 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 444.0
SHD3_k127_3771729_3 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 314.0
SHD3_k127_3771729_4 PFAM translation initiation factor SUI1 K03113 - - 0.0000000000000001511 83.0
SHD3_k127_3784815_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 466.0
SHD3_k127_3784815_1 Dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 392.0
SHD3_k127_3784815_10 guanosine tetraphosphate metabolic process K07816 - 2.7.6.5 0.00000000000000000000000000000000000000000000009407 190.0
SHD3_k127_3784815_11 Methyltransferase - - - 0.00000000000000000000000004885 109.0
SHD3_k127_3784815_12 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000002265 110.0
SHD3_k127_3784815_2 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 410.0
SHD3_k127_3784815_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 378.0
SHD3_k127_3784815_4 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 361.0
SHD3_k127_3784815_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002465 291.0
SHD3_k127_3784815_6 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000001444 250.0
SHD3_k127_3784815_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000001512 231.0
SHD3_k127_3784815_8 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000007323 226.0
SHD3_k127_3784815_9 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000001122 215.0
SHD3_k127_3788325_0 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001639 250.0
SHD3_k127_3788325_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000008429 226.0
SHD3_k127_3788325_2 Isoleucyl-tRNA synthetase - - - 0.0000000000000000000000000000000000000000000002663 182.0
SHD3_k127_3788325_3 Tricorn protease homolog K03797,K08676 - 3.4.21.102 0.000000000000000000000000009508 125.0
SHD3_k127_3788325_4 Cytochrome c - - - 0.0000000002284 66.0
SHD3_k127_3799326_0 ATP-dependent helicase activity K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 402.0
SHD3_k127_3799326_1 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000648 240.0
SHD3_k127_3799326_2 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000002044 240.0
SHD3_k127_3799326_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000003274 207.0
SHD3_k127_3799326_4 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000257 138.0
SHD3_k127_3799326_5 - - - - 0.000000000000000001065 90.0
SHD3_k127_3799326_6 DnaJ C terminal domain K09510 - - 0.000000001042 68.0
SHD3_k127_3815734_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 301.0
SHD3_k127_3815734_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000162 262.0
SHD3_k127_3815734_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000002444 222.0
SHD3_k127_3815734_3 Psort location Cytoplasmic, score 8.87 K06346 - - 0.00000000000000000000006466 108.0
SHD3_k127_3815734_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000004913 100.0
SHD3_k127_3815734_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000002364 70.0
SHD3_k127_3815734_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000002048 74.0
SHD3_k127_3831833_0 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 363.0
SHD3_k127_3831833_1 PFAM Alpha beta hydrolase K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009311 276.0
SHD3_k127_3831833_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001821 269.0
SHD3_k127_3831833_3 Pfam Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000282 128.0
SHD3_k127_3831833_4 Transcriptional regulator - - - 0.000000000356 65.0
SHD3_k127_3831833_5 OsmC-like protein - - - 0.000000001374 68.0
SHD3_k127_3831833_6 - - - - 0.0001154 56.0
SHD3_k127_3875081_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 565.0
SHD3_k127_3875081_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 316.0
SHD3_k127_3875081_2 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000001982 105.0
SHD3_k127_3875081_3 PFAM regulatory protein, MerR - - - 0.0000000000000006547 83.0
SHD3_k127_3923930_0 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 7.557e-284 890.0
SHD3_k127_3923930_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 467.0
SHD3_k127_3923930_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 326.0
SHD3_k127_3957248_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 597.0
SHD3_k127_3957248_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 382.0
SHD3_k127_3957248_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 357.0
SHD3_k127_3957248_3 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 319.0
SHD3_k127_3957248_4 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 304.0
SHD3_k127_3957248_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005817 258.0
SHD3_k127_3957248_6 Lipase (class 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000208 252.0
SHD3_k127_3957248_7 Bacterial SH3 domain homologues - - - 0.000000000000000000000000000000000000000000001046 175.0
SHD3_k127_3957248_8 - - - - 0.0000000000000000000000000000000001075 140.0
SHD3_k127_3957248_9 enzyme binding K00567,K07443 - 2.1.1.63 0.00000000000000000000000000000000224 134.0
SHD3_k127_3960147_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 577.0
SHD3_k127_3960147_1 Fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001044 248.0
SHD3_k127_3960147_2 - - - - 0.00000000000000000000000000000000000000000000000000000145 205.0
SHD3_k127_3960147_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000003077 165.0
SHD3_k127_3960147_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000002357 154.0
SHD3_k127_3960147_5 positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000000003464 70.0
SHD3_k127_3960147_6 cellulase activity - - - 0.00000000004337 77.0
SHD3_k127_3964181_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 3.291e-195 620.0
SHD3_k127_3964181_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001087 242.0
SHD3_k127_3964181_2 PFAM Na-Ca exchanger integrin-beta4 - - - 0.0000000000000000000000000000000000000000000000000000000000000389 229.0
SHD3_k127_39866_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 539.0
SHD3_k127_39866_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 371.0
SHD3_k127_39866_2 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 297.0
SHD3_k127_3993235_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.804e-230 732.0
SHD3_k127_3993235_1 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000341 300.0
SHD3_k127_3993235_10 - - - - 0.00000000009533 63.0
SHD3_k127_3993235_11 DNA uptake protein and related DNA-binding K02237 - - 0.000001973 60.0
SHD3_k127_3993235_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001168 282.0
SHD3_k127_3993235_3 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000011 244.0
SHD3_k127_3993235_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000001447 221.0
SHD3_k127_3993235_5 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000004888 151.0
SHD3_k127_3993235_6 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000007869 141.0
SHD3_k127_3993235_7 Helix-hairpin-helix motif - - - 0.00000000000000000000000000000008673 139.0
SHD3_k127_3993235_8 salt-induced outer membrane protein K07283 - - 0.0000000000005216 79.0
SHD3_k127_405004_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 9.586e-283 884.0
SHD3_k127_405004_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 3.875e-201 675.0
SHD3_k127_405004_10 Glycosyltransferase family 87 - - - 0.000000000000000000000004075 120.0
SHD3_k127_405004_2 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 550.0
SHD3_k127_405004_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 311.0
SHD3_k127_405004_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002522 281.0
SHD3_k127_405004_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000001731 233.0
SHD3_k127_405004_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000001136 197.0
SHD3_k127_405004_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000001176 178.0
SHD3_k127_405004_8 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000016 132.0
SHD3_k127_405004_9 Heavy metal translocating P-type atpase K01533,K17686,K21887 - 3.6.3.4,3.6.3.54 0.00000000000000000000000006504 126.0
SHD3_k127_4081000_0 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006869 257.0
SHD3_k127_4081000_1 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000000000000000000001066 182.0
SHD3_k127_4081000_10 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503,K19710,K21220 - 2.5.1.3,2.7.7.53 0.0000000000000001015 89.0
SHD3_k127_4081000_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000006092 69.0
SHD3_k127_4081000_12 - - - - 0.00001129 53.0
SHD3_k127_4081000_2 KR domain K07535 - - 0.000000000000000000000000000000000000000000000003807 187.0
SHD3_k127_4081000_3 - - - - 0.0000000000000000000000000000000000000000127 163.0
SHD3_k127_4081000_4 Membrane domain of glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000009732 136.0
SHD3_k127_4081000_5 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000005299 119.0
SHD3_k127_4081000_6 Putative esterase - - - 0.000000000000000000000000003465 128.0
SHD3_k127_4081000_7 phosphorelay signal transduction system - - - 0.00000000000000000000000001703 112.0
SHD3_k127_4081000_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000284 124.0
SHD3_k127_4081000_9 Transglutaminase-like superfamily - - - 0.00000000000000000000001055 104.0
SHD3_k127_4092236_0 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 416.0
SHD3_k127_4092236_1 NHL repeat K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 321.0
SHD3_k127_4092236_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000001499 203.0
SHD3_k127_4092236_3 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000003367 184.0
SHD3_k127_4092236_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000005775 141.0
SHD3_k127_4092236_5 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000107 104.0
SHD3_k127_4095111_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 482.0
SHD3_k127_4095111_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 497.0
SHD3_k127_4095111_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 459.0
SHD3_k127_4095111_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000002255 243.0
SHD3_k127_4095111_4 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000005154 135.0
SHD3_k127_4095111_5 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000008683 105.0
SHD3_k127_4111987_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 5.628e-257 819.0
SHD3_k127_4111987_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 572.0
SHD3_k127_4111987_2 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 530.0
SHD3_k127_4111987_3 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006853 282.0
SHD3_k127_4111987_4 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000003605 220.0
SHD3_k127_4111987_5 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000005767 194.0
SHD3_k127_4111987_6 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000001078 125.0
SHD3_k127_4111987_7 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000297 115.0
SHD3_k127_4149832_0 Involved in the tonB-independent uptake of proteins - - - 1.112e-195 634.0
SHD3_k127_4149832_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 304.0
SHD3_k127_4149832_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000004483 262.0
SHD3_k127_4149832_3 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000002077 175.0
SHD3_k127_4149832_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000004922 86.0
SHD3_k127_416916_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 298.0
SHD3_k127_416916_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000008343 259.0
SHD3_k127_416916_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000004124 214.0
SHD3_k127_416916_3 UPF0761 membrane protein K07058 - - 0.000000000000002196 88.0
SHD3_k127_4175148_0 Involved in the tonB-independent uptake of proteins - - - 5.611e-208 676.0
SHD3_k127_4175148_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 439.0
SHD3_k127_4175148_2 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 337.0
SHD3_k127_4175148_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000003817 235.0
SHD3_k127_4175148_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000105 197.0
SHD3_k127_4175148_5 Predicted membrane protein (DUF2127) - - - 0.000000314 63.0
SHD3_k127_4175148_6 Sodium:solute symporter family - - - 0.0001859 46.0
SHD3_k127_4175148_7 cellulase activity - - - 0.0005212 51.0
SHD3_k127_4206661_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 461.0
SHD3_k127_4206661_1 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 352.0
SHD3_k127_4206661_2 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 313.0
SHD3_k127_4206661_3 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000001676 147.0
SHD3_k127_4214765_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 2.346e-217 705.0
SHD3_k127_4214765_1 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 4.249e-207 652.0
SHD3_k127_4214765_2 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 606.0
SHD3_k127_4214765_3 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000009608 186.0
SHD3_k127_4214765_4 - - - - 0.000000000000000000000000000000000000000006227 160.0
SHD3_k127_4214765_5 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000003098 145.0
SHD3_k127_4214765_6 Dodecin K09165 - - 0.0000000000000000000000003624 106.0
SHD3_k127_4214765_7 Formamidopyrimidine-DNA glycosylase H2TH domain K05522,K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.0000000000001373 71.0
SHD3_k127_422322_0 Glycosyltransferase, group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000003823 222.0
SHD3_k127_422322_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000838 187.0
SHD3_k127_422322_2 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000001043 192.0
SHD3_k127_422322_3 glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000002758 181.0
SHD3_k127_422322_4 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000003007 153.0
SHD3_k127_422322_5 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000002221 86.0
SHD3_k127_422322_6 PFAM PEGA domain - - - 0.0000005034 61.0
SHD3_k127_4226603_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.944e-262 821.0
SHD3_k127_4226603_1 Initiation factor 2 subunit family K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 302.0
SHD3_k127_4226603_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001022 291.0
SHD3_k127_4226603_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000002932 199.0
SHD3_k127_4226603_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000002392 185.0
SHD3_k127_4226603_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000001058 106.0
SHD3_k127_4226603_6 Redoxin - - - 0.000000000000253 72.0
SHD3_k127_4226603_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000745 54.0
SHD3_k127_4226603_9 Glutathione peroxidase K02199 - - 0.0002559 46.0
SHD3_k127_4229082_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1071.0
SHD3_k127_4229082_1 Periplasmic copper-binding protein (NosD) K07218 - - 5.811e-194 628.0
SHD3_k127_4229082_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 575.0
SHD3_k127_4229082_3 ABC transporter K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 357.0
SHD3_k127_4229082_4 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004408 270.0
SHD3_k127_4229082_5 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000000001574 156.0
SHD3_k127_4229082_6 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000007512 134.0
SHD3_k127_422991_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 328.0
SHD3_k127_422991_1 ABC transporter permease K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009371 271.0
SHD3_k127_422991_2 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009667 253.0
SHD3_k127_422991_3 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000413 156.0
SHD3_k127_422991_4 Response regulator receiver domain - - - 0.0000000000000000000000000009915 120.0
SHD3_k127_4309787_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 436.0
SHD3_k127_4309787_1 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 299.0
SHD3_k127_4309787_10 fatty acid desaturase - - - 0.000000000000007491 86.0
SHD3_k127_4309787_11 - - - - 0.0000105 52.0
SHD3_k127_4309787_2 PFAM Cys Met metabolism K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 321.0
SHD3_k127_4309787_3 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000005054 286.0
SHD3_k127_4309787_4 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005993 286.0
SHD3_k127_4309787_5 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000003569 220.0
SHD3_k127_4309787_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000008624 181.0
SHD3_k127_4309787_7 lipid kinase, YegS Rv2252 BmrU family - - - 0.0000000000000000000000000000000000000006607 162.0
SHD3_k127_4309787_8 GYD domain - - - 0.000000000000000000000000000000158 131.0
SHD3_k127_4309787_9 PFAM FecR protein - - - 0.000000000000000001515 99.0
SHD3_k127_4311081_0 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 568.0
SHD3_k127_4311081_1 O-methyltransferase activity - - - 0.00000000000000001034 86.0
SHD3_k127_4311081_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553,K14160 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000005173 80.0
SHD3_k127_4327166_0 FAD linked oxidases, C-terminal domain K06911 - - 1.074e-299 951.0
SHD3_k127_4327166_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001499 233.0
SHD3_k127_4327166_2 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000007287 188.0
SHD3_k127_4327166_3 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000001031 142.0
SHD3_k127_4327166_4 transcriptional regulator (MarR - - - 0.000000000000000000002656 102.0
SHD3_k127_4342418_0 Heat shock 70 kDa protein K04043 - - 1.591e-212 668.0
SHD3_k127_4342418_1 MerR HTH family regulatory protein K13640 - - 0.00000000000000000000000000000006841 128.0
SHD3_k127_4342418_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000001146 111.0
SHD3_k127_4342418_3 Tetratricopeptide repeat - - - 0.000000000002805 80.0
SHD3_k127_4368521_0 Adenosine/AMP deaminase K01488,K21053 - 3.5.4.2,3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 451.0
SHD3_k127_4368521_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 294.0
SHD3_k127_4368521_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 298.0
SHD3_k127_4368521_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001644 262.0
SHD3_k127_4368521_4 - - - - 0.00000000000000000000000000000000000001007 160.0
SHD3_k127_4374616_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 457.0
SHD3_k127_4374616_1 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 428.0
SHD3_k127_4374616_10 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001006 81.0
SHD3_k127_4374616_11 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.00000005669 59.0
SHD3_k127_4374616_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 304.0
SHD3_k127_4374616_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000033 242.0
SHD3_k127_4374616_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000001644 207.0
SHD3_k127_4374616_5 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000372 176.0
SHD3_k127_4374616_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001798 162.0
SHD3_k127_4374616_7 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000003437 152.0
SHD3_k127_4374616_8 Belongs to the ompA family - - - 0.000000000000000000000000000622 130.0
SHD3_k127_4374616_9 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000008923 99.0
SHD3_k127_4397276_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 479.0
SHD3_k127_4397276_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 319.0
SHD3_k127_4397276_2 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000001476 213.0
SHD3_k127_4397276_3 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000922 215.0
SHD3_k127_4397276_4 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000004036 126.0
SHD3_k127_4397276_5 Protein of unknown function DUF58 - - - 0.00000000000000000000002412 111.0
SHD3_k127_4397276_6 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000008818 101.0
SHD3_k127_4416945_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 415.0
SHD3_k127_4416945_1 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001449 292.0
SHD3_k127_444065_0 Belongs to the thiolase family K00626,K07508 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 425.0
SHD3_k127_444065_1 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 385.0
SHD3_k127_444065_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000001682 273.0
SHD3_k127_444065_3 Beta-lactamase - - - 0.0000000000000000000000000007424 117.0
SHD3_k127_444065_4 - - - - 0.00000697 56.0
SHD3_k127_4447107_0 class II (D K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 561.0
SHD3_k127_4447107_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 531.0
SHD3_k127_4447107_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 419.0
SHD3_k127_4447107_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000007222 150.0
SHD3_k127_4447107_4 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000001493 154.0
SHD3_k127_4447107_5 nuclease activity - - - 0.0000000000000000000000008488 108.0
SHD3_k127_4447107_6 toxin-antitoxin pair type II binding - - - 0.000000001467 65.0
SHD3_k127_4449630_0 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 552.0
SHD3_k127_4449630_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000198 111.0
SHD3_k127_4449630_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000008646 97.0
SHD3_k127_4449630_3 ABC-type polysaccharide polyol phosphate transport system ATPase component K01990,K09691 - - 0.00000000000000001715 84.0
SHD3_k127_4478895_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000005893 145.0
SHD3_k127_4478895_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000008358 63.0
SHD3_k127_4478895_2 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000001975 59.0
SHD3_k127_4478895_3 redox protein, regulator of disulfide bond formation - - - 0.0000002986 61.0
SHD3_k127_453843_0 Sortilin, neurotensin receptor 3, - - - 8.904e-227 715.0
SHD3_k127_453843_1 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 365.0
SHD3_k127_453843_10 - - - - 0.00000987 48.0
SHD3_k127_453843_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 311.0
SHD3_k127_453843_3 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000000000000000000000000000000005182 212.0
SHD3_k127_453843_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000005626 202.0
SHD3_k127_453843_5 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000000000000004035 199.0
SHD3_k127_453843_6 TonB dependent receptor K02014 - - 0.000000000000000000001645 111.0
SHD3_k127_453843_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000003073 94.0
SHD3_k127_453843_9 Thioredoxin-like - - - 0.0000001086 55.0
SHD3_k127_4551384_0 peptidase S45, penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 484.0
SHD3_k127_4551384_1 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 351.0
SHD3_k127_4551384_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 325.0
SHD3_k127_4551384_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000852 290.0
SHD3_k127_4551384_4 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001091 274.0
SHD3_k127_4551384_5 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000005138 155.0
SHD3_k127_4551384_6 Yip1 domain - - - 0.000000000000007035 83.0
SHD3_k127_4552197_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00244,K00278 GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.4,1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 606.0
SHD3_k127_4552197_1 peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 520.0
SHD3_k127_4552197_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 439.0
SHD3_k127_4552197_3 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001172 278.0
SHD3_k127_4552197_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000002046 226.0
SHD3_k127_4552197_5 Mannosyltransferase (PIG-V) - - - 0.000000000000000000000000000008007 134.0
SHD3_k127_4564935_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 537.0
SHD3_k127_4564935_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001433 301.0
SHD3_k127_4564935_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000001439 130.0
SHD3_k127_4564935_3 oxidoreductase activity - - - 0.000000000000000000000000002123 130.0
SHD3_k127_4564935_4 arylsulfatase activity - - - 0.0000000000000000001213 100.0
SHD3_k127_460571_0 PHP domain protein K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 515.0
SHD3_k127_460571_1 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 339.0
SHD3_k127_460571_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005094 287.0
SHD3_k127_460571_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002246 252.0
SHD3_k127_460571_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000006254 198.0
SHD3_k127_460571_5 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000022 198.0
SHD3_k127_460571_6 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000009981 186.0
SHD3_k127_460571_7 Redoxin - - - 0.0000000000000000000000000000000000009226 143.0
SHD3_k127_460571_8 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360 3.1.3.97 0.0000000000001179 71.0
SHD3_k127_460571_9 Bacterial regulatory proteins, tetR family - - - 0.000003135 57.0
SHD3_k127_4638622_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 3.311e-205 658.0
SHD3_k127_4638622_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 388.0
SHD3_k127_4638622_2 membrane - - - 0.000000000000000006863 94.0
SHD3_k127_4638622_3 Sigma-70, region 4 K03088 - - 0.00000000001269 76.0
SHD3_k127_4638622_4 ATP-independent chaperone mediated protein folding K06006 - - 0.0000000004471 67.0
SHD3_k127_4642725_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 529.0
SHD3_k127_4642725_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002086 262.0
SHD3_k127_4642725_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000232 238.0
SHD3_k127_4642725_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000002846 122.0
SHD3_k127_4642725_4 Metallo-beta-lactamase superfamily - - - 0.0006046 45.0
SHD3_k127_4643530_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 292.0
SHD3_k127_4643530_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000075 188.0
SHD3_k127_4643530_2 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000001007 176.0
SHD3_k127_4643530_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000009868 117.0
SHD3_k127_4643530_4 Adenylate cyclase - - - 0.00000000000000000000002519 115.0
SHD3_k127_4655746_0 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000001464 186.0
SHD3_k127_4655746_1 Zn peptidase - - - 0.0000000000000000000000000000000006316 148.0
SHD3_k127_4655746_2 STAS domain K04749 - - 0.000000000000000000000000000000004959 132.0
SHD3_k127_4655746_3 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000004656 118.0
SHD3_k127_4712097_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.089e-210 671.0
SHD3_k127_4712097_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 417.0
SHD3_k127_4712097_2 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 329.0
SHD3_k127_4712097_3 PFAM Multiple antibiotic resistance (MarC)-related K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001139 247.0
SHD3_k127_4712097_4 EamA-like transporter family - - - 0.00001036 48.0
SHD3_k127_4761775_0 Spermine/spermidine synthase domain - - - 3.197e-310 982.0
SHD3_k127_4761775_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 327.0
SHD3_k127_4761775_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 292.0
SHD3_k127_4761775_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000165 183.0
SHD3_k127_4761775_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000004719 167.0
SHD3_k127_4761775_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000001919 109.0
SHD3_k127_4772252_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 423.0
SHD3_k127_4772252_1 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 374.0
SHD3_k127_4772252_2 COG0644 Dehydrogenases (flavoproteins) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 333.0
SHD3_k127_4772252_3 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002517 267.0
SHD3_k127_4772252_4 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000573 160.0
SHD3_k127_4772252_5 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000009285 72.0
SHD3_k127_4772252_6 aspartate kinase activity - - - 0.0000000003393 66.0
SHD3_k127_4772252_7 PFAM GGDEF domain containing protein - - - 0.0000000708 60.0
SHD3_k127_4815197_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 8.835e-230 723.0
SHD3_k127_4815197_1 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 593.0
SHD3_k127_4815197_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001447 291.0
SHD3_k127_4815197_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002937 295.0
SHD3_k127_4815197_4 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000001536 252.0
SHD3_k127_4815197_5 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000006548 143.0
SHD3_k127_4815197_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000006616 137.0
SHD3_k127_4815197_7 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000001923 106.0
SHD3_k127_4816779_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00004687 56.0
SHD3_k127_4875680_0 PFAM peptidase M13 K07386 - - 7.815e-223 714.0
SHD3_k127_4921136_0 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 511.0
SHD3_k127_4921136_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 434.0
SHD3_k127_4921136_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 401.0
SHD3_k127_4921136_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 315.0
SHD3_k127_4921136_4 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005119 276.0
SHD3_k127_4921136_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003935 265.0
SHD3_k127_4921136_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000005974 256.0
SHD3_k127_4921136_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000004941 116.0
SHD3_k127_4921136_8 Cell division protein FtsQ K03589 - - 0.00000000193 68.0
SHD3_k127_4938320_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 4.748e-196 638.0
SHD3_k127_4938320_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 505.0
SHD3_k127_4938320_2 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 500.0
SHD3_k127_4938320_3 amino acid transport system, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 429.0
SHD3_k127_4938320_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002948 276.0
SHD3_k127_4938320_5 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000001456 181.0
SHD3_k127_4951999_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 535.0
SHD3_k127_4951999_1 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 405.0
SHD3_k127_4951999_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007568 251.0
SHD3_k127_4951999_3 NHL repeat - - - 0.000000000000000000000000000006054 140.0
SHD3_k127_4951999_4 integral membrane protein - - - 0.0000000000009179 76.0
SHD3_k127_4977218_0 CoA binding domain K01905,K22224 - 6.2.1.13 5.351e-198 637.0
SHD3_k127_4977218_1 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 571.0
SHD3_k127_4977218_2 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 415.0
SHD3_k127_4977218_3 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000001495 226.0
SHD3_k127_4977218_4 - - - - 0.00000000000000000000000000000000000000000000000000003399 195.0
SHD3_k127_4978428_0 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004487 282.0
SHD3_k127_4978428_1 rRNA methylase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000002531 263.0
SHD3_k127_4978428_2 Psort location Cytoplasmic, score K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000003762 235.0
SHD3_k127_4978428_3 surface antigen variable number - - - 0.00000000000000000000000000000000000000000000000000000000001355 238.0
SHD3_k127_4978428_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000001136 206.0
SHD3_k127_4978428_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000475 158.0
SHD3_k127_4978428_6 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000006089 143.0
SHD3_k127_4978428_8 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00002409 48.0
SHD3_k127_5034831_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.834e-206 679.0
SHD3_k127_5034831_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 404.0
SHD3_k127_5034831_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000004315 156.0
SHD3_k127_5034831_11 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000005728 166.0
SHD3_k127_5034831_12 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000004558 144.0
SHD3_k127_5034831_13 Could be involved in septation K06412 - - 0.00000000000000000000000000000001255 130.0
SHD3_k127_5034831_14 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000005287 134.0
SHD3_k127_5034831_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000004803 142.0
SHD3_k127_5034831_16 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000005071 118.0
SHD3_k127_5034831_17 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000009148 111.0
SHD3_k127_5034831_18 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000003315 111.0
SHD3_k127_5034831_19 Peptidase M22 glycoprotease K01409,K14742 - 2.3.1.234 0.00000000000000000004483 98.0
SHD3_k127_5034831_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 343.0
SHD3_k127_5034831_20 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000002282 87.0
SHD3_k127_5034831_21 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000006173 93.0
SHD3_k127_5034831_22 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000005063 81.0
SHD3_k127_5034831_23 Predicted membrane protein (DUF2232) - - - 0.00000004518 64.0
SHD3_k127_5034831_24 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000005412 65.0
SHD3_k127_5034831_25 Protein of unknown function (DUF465) - - - 0.0000228 50.0
SHD3_k127_5034831_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000005415 231.0
SHD3_k127_5034831_4 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000001517 208.0
SHD3_k127_5034831_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000005631 174.0
SHD3_k127_5034831_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000001019 169.0
SHD3_k127_5034831_7 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000003146 171.0
SHD3_k127_5034831_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000009633 166.0
SHD3_k127_5034831_9 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000004889 158.0
SHD3_k127_5037328_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 522.0
SHD3_k127_5037328_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 338.0
SHD3_k127_5037328_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 329.0
SHD3_k127_5037328_3 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 318.0
SHD3_k127_5037328_4 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 301.0
SHD3_k127_5037328_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000004363 234.0
SHD3_k127_5037328_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000007947 181.0
SHD3_k127_5037328_7 PAP2 superfamily - - - 0.000000000000000000000000000000000001926 150.0
SHD3_k127_5037328_8 protein conserved in bacteria - - - 0.000001031 61.0
SHD3_k127_506820_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 445.0
SHD3_k127_506820_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 336.0
SHD3_k127_506820_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000002829 214.0
SHD3_k127_506820_3 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000002012 211.0
SHD3_k127_5071225_0 Alcohol dehydrogenase GroES-like domain K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 512.0
SHD3_k127_5071225_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 436.0
SHD3_k127_5071225_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007961 239.0
SHD3_k127_5071225_3 Belongs to the glycosyl hydrolase 26 family K01218 - 3.2.1.78 0.00000000000000000000000000000000000000000001194 180.0
SHD3_k127_5071225_4 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000008739 124.0
SHD3_k127_5071225_5 Peptidase dimerisation domain - - - 0.0000000000000005152 85.0
SHD3_k127_5071225_6 - - - - 0.00000000000000069 88.0
SHD3_k127_5071225_7 YjbR - - - 0.000000001039 66.0
SHD3_k127_5071316_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 574.0
SHD3_k127_5071316_1 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 336.0
SHD3_k127_5071316_2 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000003 278.0
SHD3_k127_5071316_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000001808 228.0
SHD3_k127_5071316_4 peptidase S9 - - - 0.0000000000000000000000000000000000000000000000002128 177.0
SHD3_k127_5083609_0 pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 470.0
SHD3_k127_5083609_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 379.0
SHD3_k127_5083609_10 TIGRFAM DNA binding domain protein, excisionase family - - - 0.0000005593 55.0
SHD3_k127_5083609_2 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001329 250.0
SHD3_k127_5083609_3 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000001047 214.0
SHD3_k127_5083609_4 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000008463 208.0
SHD3_k127_5083609_5 - - - - 0.000000000000000000000000000000000000001349 158.0
SHD3_k127_5083609_6 DsrC like protein K11179 - - 0.0000000000000000000000000000001259 129.0
SHD3_k127_5083609_7 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000002439 123.0
SHD3_k127_5083609_8 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000001504 110.0
SHD3_k127_5083609_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000001556 105.0
SHD3_k127_5147024_0 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 371.0
SHD3_k127_5147024_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 304.0
SHD3_k127_5147024_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 292.0
SHD3_k127_5147024_3 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002276 276.0
SHD3_k127_5147024_4 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000002242 215.0
SHD3_k127_5147024_5 DinB family - - - 0.000000000000000000000000000000000001242 155.0
SHD3_k127_5147024_6 PFAM EamA-like transporter family - - - 0.000000000000000000000000002113 122.0
SHD3_k127_5147024_7 BlaR1 peptidase M56 - - - 0.00000000000004677 84.0
SHD3_k127_5147024_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000003464 64.0
SHD3_k127_5148317_0 NAT, N-acetyltransferase, of N-acetylglutamate synthase K22478 - 2.3.1.1,2.7.2.8 0.000000000000000000000000000000000000000000000000000004127 205.0
SHD3_k127_5148317_1 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000001235 144.0
SHD3_k127_5148317_2 4Fe-4S binding domain - - - 0.000000000000000000000000000006833 120.0
SHD3_k127_5148317_3 Histidine kinase K10681 - 2.7.13.3 0.000000000000000000002199 108.0
SHD3_k127_5148317_4 - - - - 0.0000166 49.0
SHD3_k127_518383_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002001 282.0
SHD3_k127_518383_1 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001404 252.0
SHD3_k127_518383_2 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000303 164.0
SHD3_k127_518383_3 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000001721 172.0
SHD3_k127_518383_4 glycosyl - - - 0.0003976 51.0
SHD3_k127_5189625_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.375e-225 710.0
SHD3_k127_5189625_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 518.0
SHD3_k127_5189625_2 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000001465 118.0
SHD3_k127_5189625_3 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000004272 107.0
SHD3_k127_5189625_4 mRNA binding - - - 0.000000000000000002036 85.0
SHD3_k127_5189625_5 Protein of unknown function (DUF507) K09804 - - 0.000006504 51.0
SHD3_k127_5189625_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.00001094 48.0
SHD3_k127_5191856_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 3.263e-226 736.0
SHD3_k127_5191856_1 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000007687 252.0
SHD3_k127_5191856_2 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000001237 217.0
SHD3_k127_5191856_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000007895 84.0
SHD3_k127_5191856_4 efflux transmembrane transporter activity K12340,K15725 - - 0.00001191 54.0
SHD3_k127_5192453_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 464.0
SHD3_k127_5192453_1 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000006832 221.0
SHD3_k127_5192453_2 amine dehydrogenase activity K20276 - - 0.000003303 59.0
SHD3_k127_5225751_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 2.071e-306 959.0
SHD3_k127_5225751_1 Isocitrate lyase family K01637 - 4.1.3.1 4.33e-209 658.0
SHD3_k127_5225751_10 MFS/sugar transport protein K08223 - - 0.00000000000000000002889 93.0
SHD3_k127_5225751_2 IrrE N-terminal-like domain K07110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 562.0
SHD3_k127_5225751_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 433.0
SHD3_k127_5225751_4 formate dehydrogenase K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 329.0
SHD3_k127_5225751_5 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000004688 263.0
SHD3_k127_5225751_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
SHD3_k127_5225751_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002165 251.0
SHD3_k127_5225751_8 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000003765 172.0
SHD3_k127_5225751_9 protein involved in formate dehydrogenase formation K02380 - - 0.000000000000000000000000001345 123.0
SHD3_k127_5230462_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 337.0
SHD3_k127_5230462_1 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 313.0
SHD3_k127_5230462_2 Ferritin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009103 259.0
SHD3_k127_5230462_3 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000007991 118.0
SHD3_k127_525386_0 Carboxypeptidase regulatory-like domain - - - 7.162e-313 989.0
SHD3_k127_525386_1 secondary active sulfate transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 492.0
SHD3_k127_525386_2 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 407.0
SHD3_k127_525386_3 Phosphoglycerate mutase family - - - 0.000000000000000000003927 100.0
SHD3_k127_525386_4 DNA-templated transcription, initiation K03088,K07263 - - 0.000000000000000008327 85.0
SHD3_k127_52623_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 612.0
SHD3_k127_52623_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 462.0
SHD3_k127_52623_10 Beta-galactosidase - - - 0.00000000002032 78.0
SHD3_k127_52623_11 Participates in both transcription termination and antitermination K02600 - - 0.000125 50.0
SHD3_k127_52623_2 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 432.0
SHD3_k127_52623_3 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 419.0
SHD3_k127_52623_4 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 316.0
SHD3_k127_52623_5 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001309 264.0
SHD3_k127_52623_6 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001755 261.0
SHD3_k127_52623_7 - - - - 0.00000000000000000000000000000000000000000000000000000000003815 225.0
SHD3_k127_52623_8 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000006561 195.0
SHD3_k127_52623_9 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000005881 137.0
SHD3_k127_5264378_0 peptidyl-tyrosine sulfation - - - 3.292e-221 705.0
SHD3_k127_5264378_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 494.0
SHD3_k127_5264378_2 Transcriptional regulator - - - 0.00000000000000000000211 100.0
SHD3_k127_5264378_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000001774 80.0
SHD3_k127_5293598_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 389.0
SHD3_k127_5293598_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 361.0
SHD3_k127_5293598_10 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000003581 109.0
SHD3_k127_5293598_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000002184 83.0
SHD3_k127_5293598_12 SMART Rhodanese domain protein - - - 0.0000000001173 63.0
SHD3_k127_5293598_2 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 317.0
SHD3_k127_5293598_3 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 304.0
SHD3_k127_5293598_4 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001149 284.0
SHD3_k127_5293598_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000001546 245.0
SHD3_k127_5293598_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000007348 210.0
SHD3_k127_5293598_7 - - - - 0.00000000000000000000000000000000000000000001903 174.0
SHD3_k127_5293598_8 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000137 137.0
SHD3_k127_5293598_9 Response regulator receiver domain - - - 0.00000000000000000000000000008462 124.0
SHD3_k127_5296263_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 467.0
SHD3_k127_5296263_1 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 442.0
SHD3_k127_5296263_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000001662 150.0
SHD3_k127_5296263_3 acid phosphatase activity - - - 0.00000000000000000000000000008034 123.0
SHD3_k127_5296263_4 DNA-binding transcription factor activity - - - 0.00000000000000000000002668 106.0
SHD3_k127_5296263_5 TIGRFAM redox-active disulfide protein 2 - - - 0.000000000000000000255 90.0
SHD3_k127_5296263_6 Transcriptional regulator K03892,K21903 - - 0.0000000000000000003934 93.0
SHD3_k127_5335630_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.28e-237 748.0
SHD3_k127_5335630_1 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 401.0
SHD3_k127_5335630_10 - - - - 0.00000000000000003311 83.0
SHD3_k127_5335630_11 - - - - 0.0000000009855 60.0
SHD3_k127_5335630_12 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000001312 63.0
SHD3_k127_5335630_13 UPF0391 membrane protein - - - 0.00001611 57.0
SHD3_k127_5335630_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001155 275.0
SHD3_k127_5335630_3 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000001804 190.0
SHD3_k127_5335630_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000004721 188.0
SHD3_k127_5335630_5 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000002501 161.0
SHD3_k127_5335630_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000004952 167.0
SHD3_k127_5335630_7 - - - - 0.000000000000000000000000000001171 125.0
SHD3_k127_5335630_8 Serine aminopeptidase, S33 - - - 0.00000000000000000001308 96.0
SHD3_k127_5335630_9 Serine aminopeptidase, S33 - - - 0.00000000000000000003568 104.0
SHD3_k127_534161_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 313.0
SHD3_k127_534161_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000004609 247.0
SHD3_k127_534161_2 - - - - 0.00000000000000000000000000001189 128.0
SHD3_k127_534161_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000332 86.0
SHD3_k127_5351078_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.032e-239 752.0
SHD3_k127_5351078_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 442.0
SHD3_k127_5351078_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 416.0
SHD3_k127_5351078_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 395.0
SHD3_k127_5351078_4 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 388.0
SHD3_k127_5351078_5 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002694 276.0
SHD3_k127_5351078_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000004028 220.0
SHD3_k127_5351078_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000004536 141.0
SHD3_k127_5351078_8 Glycosyl transferases group 1 K21001 - - 0.00000000000000007342 91.0
SHD3_k127_5351955_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.982e-241 764.0
SHD3_k127_5351955_1 Pyridine nucleotide-disulphide oxidoreductase - - - 1.78e-218 698.0
SHD3_k127_5351955_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000003595 173.0
SHD3_k127_5351955_11 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000001163 169.0
SHD3_k127_5351955_12 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000003814 137.0
SHD3_k127_5351955_13 diguanylate cyclase activity - - - 0.000000000000000000000000000001588 136.0
SHD3_k127_5351955_14 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000009848 126.0
SHD3_k127_5351955_15 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000001341 139.0
SHD3_k127_5351955_16 The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF- YajC-YidC subcomplex facilitates these functions K03210 - - 0.0000000000000000000003764 99.0
SHD3_k127_5351955_18 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000891 94.0
SHD3_k127_5351955_19 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.000000000000000001257 87.0
SHD3_k127_5351955_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 441.0
SHD3_k127_5351955_20 chaperone-mediated protein folding - - - 0.00000000000000517 91.0
SHD3_k127_5351955_21 Protein of unknown function (FYDLN_acid) - - - 0.0000000000003896 73.0
SHD3_k127_5351955_22 Tetratricopeptide repeat - - - 0.000001448 59.0
SHD3_k127_5351955_23 PFAM Fimbrial assembly family protein K02662,K02663 - - 0.000003124 57.0
SHD3_k127_5351955_24 chaperone-mediated protein folding - - - 0.00001073 60.0
SHD3_k127_5351955_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 372.0
SHD3_k127_5351955_4 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 334.0
SHD3_k127_5351955_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 334.0
SHD3_k127_5351955_6 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 314.0
SHD3_k127_5351955_7 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001119 281.0
SHD3_k127_5351955_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004832 284.0
SHD3_k127_5351955_9 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.000000000000000000000000000000000000000000000000004019 191.0
SHD3_k127_5360423_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 503.0
SHD3_k127_5360423_1 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 486.0
SHD3_k127_5360423_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 401.0
SHD3_k127_5360423_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000003853 232.0
SHD3_k127_5360423_4 DinB family - - - 0.00000000000000000000000000000000000000000000000005575 184.0
SHD3_k127_5360423_5 - - - - 0.00000000000000000000000000003295 132.0
SHD3_k127_5360423_6 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.00000000000000000000183 97.0
SHD3_k127_5360423_7 Protein of unknown function (DUF3788) - - - 0.000000000000000000004658 97.0
SHD3_k127_5404333_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 1.868e-227 733.0
SHD3_k127_5404333_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 587.0
SHD3_k127_5404333_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 417.0
SHD3_k127_5404333_3 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001243 274.0
SHD3_k127_5404333_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000001561 243.0
SHD3_k127_5404333_5 YceI-like domain - - - 0.00000000000000000000000000000000001996 151.0
SHD3_k127_5404333_8 Glutathione peroxidase - - - 0.00000000000143 78.0
SHD3_k127_5414040_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 432.0
SHD3_k127_5414040_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000023 142.0
SHD3_k127_5414040_2 domain, Protein - - - 0.00000000000000000000000000000002842 146.0
SHD3_k127_5414040_3 Mechanosensitive ion channel - - - 0.00000000000000000000000000008005 128.0
SHD3_k127_5414040_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000001298 117.0
SHD3_k127_5457615_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 512.0
SHD3_k127_5457615_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 442.0
SHD3_k127_5457615_2 Dihydroorotate dehydrogenase K17723 GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 396.0
SHD3_k127_5457615_3 deaminase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000007323 242.0
SHD3_k127_5457615_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000007521 139.0
SHD3_k127_5457615_5 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000007932 105.0
SHD3_k127_5457615_6 NAD(P)H quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000891 94.0
SHD3_k127_5497768_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 1099.0
SHD3_k127_5497768_1 Peptidase m28 - - - 7.571e-213 674.0
SHD3_k127_5497768_2 PFAM peptidase M28 - - - 1.912e-199 638.0
SHD3_k127_5497768_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 499.0
SHD3_k127_5497768_4 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 363.0
SHD3_k127_5497768_5 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 326.0
SHD3_k127_5515032_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 585.0
SHD3_k127_5515032_1 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 349.0
SHD3_k127_5515032_10 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000003031 142.0
SHD3_k127_5515032_11 Tetratricopeptide repeat - - - 0.00000000002229 73.0
SHD3_k127_5515032_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 306.0
SHD3_k127_5515032_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 325.0
SHD3_k127_5515032_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 313.0
SHD3_k127_5515032_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001546 267.0
SHD3_k127_5515032_6 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K03148,K21029 - 2.7.7.73,2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000788 259.0
SHD3_k127_5515032_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000001815 215.0
SHD3_k127_5515032_8 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000001594 171.0
SHD3_k127_5515032_9 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000005987 174.0
SHD3_k127_5525244_0 AAA ATPase domain - - - 1.63e-316 1024.0
SHD3_k127_5525244_1 radical SAM domain protein - - - 4.248e-224 706.0
SHD3_k127_5525244_10 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005404 283.0
SHD3_k127_5525244_11 Homocysteine S-methyltransferase - - - 0.0000000001549 65.0
SHD3_k127_5525244_12 Belongs to the phosphoenolpyruvate carboxykinase (ATP) family K01610 - 4.1.1.49 0.00008702 45.0
SHD3_k127_5525244_2 Belongs to the phosphoenolpyruvate carboxykinase (ATP) family K01610 - 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 581.0
SHD3_k127_5525244_3 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 587.0
SHD3_k127_5525244_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 419.0
SHD3_k127_5525244_5 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 361.0
SHD3_k127_5525244_6 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 341.0
SHD3_k127_5525244_7 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 316.0
SHD3_k127_5525244_8 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 321.0
SHD3_k127_5525244_9 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003125 287.0
SHD3_k127_5538617_0 cluster binding protein K18929 - - 1.317e-212 683.0
SHD3_k127_5538617_1 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 353.0
SHD3_k127_5538617_2 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002616 261.0
SHD3_k127_5538617_3 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004971 265.0
SHD3_k127_5538617_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000007406 226.0
SHD3_k127_5538617_5 COG3839 ABC-type sugar transport systems, ATPase components - - - 0.0000000000000000000000000001685 120.0
SHD3_k127_5554877_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 534.0
SHD3_k127_5554877_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000001023 114.0
SHD3_k127_5554877_2 Lipopolysaccharide-assembly - - - 0.0000000003861 72.0
SHD3_k127_5554877_3 Ribosomal protein S20 K02968 - - 0.000000004814 60.0
SHD3_k127_5558774_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.028e-208 661.0
SHD3_k127_5558774_1 PFAM Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000006688 252.0
SHD3_k127_5558774_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000006067 246.0
SHD3_k127_5558774_3 oxidoreductase activity - - - 0.00000000000009786 84.0
SHD3_k127_5558774_4 Domain of unknown function (DUF4388) - - - 0.0001924 54.0
SHD3_k127_5581206_0 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 611.0
SHD3_k127_5581206_1 PFAM Cytochrome b b6 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 318.0
SHD3_k127_5581206_2 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000029 205.0
SHD3_k127_5581206_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000168 128.0
SHD3_k127_5581206_4 HEAT repeat - - - 0.00000004714 66.0
SHD3_k127_5650573_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 501.0
SHD3_k127_5650573_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000002789 196.0
SHD3_k127_5650573_2 GAF domain - - - 0.0000000000000000000000000000000000000000000000005542 195.0
SHD3_k127_5650573_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000002146 104.0
SHD3_k127_5650573_4 Memo-like protein K06990 - - 0.00000003857 64.0
SHD3_k127_5650573_5 COG COG3291 FOG PKD repeat - - - 0.000002474 61.0
SHD3_k127_5679317_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1682.0
SHD3_k127_5679317_1 COG4263 Nitrous oxide reductase K00376 - 1.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 568.0
SHD3_k127_5679317_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 386.0
SHD3_k127_5679317_3 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000001025 222.0
SHD3_k127_5679317_4 Cytochrome c K00406,K16255 - - 0.0000000000000000000000000000000000000000000007864 181.0
SHD3_k127_5679317_5 Pas domain - - - 0.000000000000000000002186 104.0
SHD3_k127_5679317_6 - - - - 0.0000000000000006141 88.0
SHD3_k127_5679317_7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000005176 72.0
SHD3_k127_5679317_8 Universal stress protein - - - 0.0000002744 60.0
SHD3_k127_5683371_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 426.0
SHD3_k127_5683371_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 414.0
SHD3_k127_5683371_2 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 409.0
SHD3_k127_5683371_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 381.0
SHD3_k127_5683371_4 Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA K06969 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 299.0
SHD3_k127_5683371_5 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000005085 196.0
SHD3_k127_5683371_6 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000003904 182.0
SHD3_k127_5683371_7 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000006092 140.0
SHD3_k127_5683371_8 cheY-homologous receiver domain - - - 0.0000000000000000000000000000001498 128.0
SHD3_k127_5683371_9 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000133 102.0
SHD3_k127_5688035_0 Pyruvate ferredoxin oxidoreductase and related K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 412.0
SHD3_k127_5688035_1 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001215 293.0
SHD3_k127_5688035_2 - - - - 0.00000000000000000000000000000000000000000000000000008879 200.0
SHD3_k127_5688035_3 Aminotransferase class-V - - - 0.00000000000000000000000000006655 119.0
SHD3_k127_5690243_0 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000195 204.0
SHD3_k127_5690243_1 SMART protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000000003119 156.0
SHD3_k127_590626_1 Radical SAM superfamily - - - 0.000000000000000000000000000000004619 147.0
SHD3_k127_590626_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000001635 82.0
SHD3_k127_590626_3 Glycosyl transferase family 21 - - - 0.000000000002998 76.0
SHD3_k127_618712_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 437.0
SHD3_k127_618712_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 345.0
SHD3_k127_618712_2 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 339.0
SHD3_k127_618712_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000007621 197.0
SHD3_k127_618712_4 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000002504 186.0
SHD3_k127_619679_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 560.0
SHD3_k127_619679_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 449.0
SHD3_k127_619679_2 Involved in the biosynthesis of porphyrin-containing compound K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 457.0
SHD3_k127_619679_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 336.0
SHD3_k127_619679_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 310.0
SHD3_k127_619679_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001503 268.0
SHD3_k127_619679_6 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000004382 201.0
SHD3_k127_671319_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 373.0
SHD3_k127_671319_1 metallopeptidase activity K01993,K13408,K16922 - - 0.000000000000000000000000000000000000000000000000009733 205.0
SHD3_k127_671319_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.0000000000000000000000000000000000000000000003631 183.0
SHD3_k127_671319_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000001004 119.0
SHD3_k127_671319_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000001356 92.0
SHD3_k127_67265_0 AAA ATPase, central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 467.0
SHD3_k127_67265_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 399.0
SHD3_k127_67265_2 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000156 143.0
SHD3_k127_67265_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000008631 83.0
SHD3_k127_678423_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 581.0
SHD3_k127_678423_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 351.0
SHD3_k127_678423_2 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 350.0
SHD3_k127_678423_3 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 316.0
SHD3_k127_678423_4 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003698 288.0
SHD3_k127_678423_5 Ferric siderophore transporter, periplasmic energy transduction protein TonB K03832 - - 0.00000003106 66.0
SHD3_k127_719383_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 452.0
SHD3_k127_719383_1 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 389.0
SHD3_k127_719383_2 - - - - 0.00000000000000000000000000000000000000000000000000001372 198.0
SHD3_k127_719383_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000005411 169.0
SHD3_k127_719383_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000002001 89.0
SHD3_k127_734952_0 mRNA catabolic process K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 552.0
SHD3_k127_734952_1 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 308.0
SHD3_k127_734952_2 involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000001476 213.0
SHD3_k127_734952_3 O-Antigen ligase K18814 - - 0.0000000000000000000000000146 123.0
SHD3_k127_734952_4 PFAM glycosyl transferase group 1 - - - 0.0000000000000000006715 100.0
SHD3_k127_734952_5 Cell division protein ZapA K09888 - - 0.0000000000041 70.0
SHD3_k127_734952_6 Belongs to the UPF0434 family K09791 - - 0.0000001103 57.0
SHD3_k127_734952_7 phenylalanyl-tRNA synthetase (beta subunit) K01890 - 6.1.1.20 0.00008191 48.0
SHD3_k127_738143_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1181.0
SHD3_k127_738143_1 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 573.0
SHD3_k127_738143_2 PAS fold-4 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 576.0
SHD3_k127_738143_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 297.0
SHD3_k127_738143_4 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000139 271.0
SHD3_k127_738143_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000001112 152.0
SHD3_k127_738143_6 COG1651 Protein-disulfide isomerase K21990 - - 0.000000000000000000000000000003768 133.0
SHD3_k127_738143_7 - - - - 0.0000000000000000000000000001997 129.0
SHD3_k127_738143_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000174 75.0
SHD3_k127_738143_9 Plasmid stability protein K21495 - - 0.0000002703 55.0
SHD3_k127_740114_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 360.0
SHD3_k127_740114_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 309.0
SHD3_k127_740114_2 PFAM peptidase M24 K01262,K01271,K01274 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000791 249.0
SHD3_k127_740114_3 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000001478 251.0
SHD3_k127_740114_4 TPR repeat - - - 0.000001515 60.0
SHD3_k127_748478_0 COG0464 ATPases of the AAA class - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 426.0
SHD3_k127_748478_1 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000001565 187.0
SHD3_k127_748478_2 protein homooligomerization - - - 0.000000000000000000000000000000003937 147.0
SHD3_k127_748478_3 Domain of unknown function (DUF4340) - - - 0.0000000000000008857 91.0
SHD3_k127_748796_0 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 289.0
SHD3_k127_748796_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000001286 216.0
SHD3_k127_748796_2 GHMP kinase K00869,K07031 - 2.7.1.168,2.7.1.36 0.00000000000000000000000000000000000000000000000000003526 200.0
SHD3_k127_76484_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 475.0
SHD3_k127_76484_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006104 283.0
SHD3_k127_76484_2 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000004762 216.0
SHD3_k127_76484_3 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000102 206.0
SHD3_k127_76484_4 DNA-sulfur modification-associated - - - 0.0000000000000000001147 101.0
SHD3_k127_7774_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 9.366e-234 773.0
SHD3_k127_7774_1 PFAM Pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 581.0
SHD3_k127_7774_10 PFAM CBS domain containing protein K04767 - - 0.0000000000000000000000000000000000000000000000000002609 192.0
SHD3_k127_7774_11 AAA domain - - - 0.000000000000000000000000000000000000000000003402 168.0
SHD3_k127_7774_12 cheY-homologous receiver domain - - - 0.0000000000000000000000000001122 128.0
SHD3_k127_7774_13 - - - - 0.0000000000000000000000000003425 119.0
SHD3_k127_7774_14 COG1145 Ferredoxin - - - 0.00000000000000000000000001486 114.0
SHD3_k127_7774_15 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000004597 105.0
SHD3_k127_7774_16 Transcriptional regulator - - - 0.00000000000000003255 89.0
SHD3_k127_7774_18 Carboxymuconolactone decarboxylase family - - - 0.000000000000004626 85.0
SHD3_k127_7774_19 - - - - 0.0001153 52.0
SHD3_k127_7774_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 468.0
SHD3_k127_7774_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 339.0
SHD3_k127_7774_4 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 310.0
SHD3_k127_7774_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 320.0
SHD3_k127_7774_6 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 288.0
SHD3_k127_7774_7 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003004 291.0
SHD3_k127_7774_8 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000009419 255.0
SHD3_k127_7774_9 methionine sulfoxide reductase K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000001155 233.0
SHD3_k127_797388_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 544.0
SHD3_k127_797388_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 455.0
SHD3_k127_797388_2 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 410.0
SHD3_k127_797388_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002442 245.0
SHD3_k127_797388_4 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000001546 157.0
SHD3_k127_797388_6 COGs COG3947 Response regulator containing CheY-like receiver and SARP domains - - - 0.0000263 52.0
SHD3_k127_81608_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 3.126e-230 719.0
SHD3_k127_81608_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 357.0
SHD3_k127_81608_10 Transglutaminase-like superfamily - - - 0.000000000000000000000000004168 128.0
SHD3_k127_81608_11 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000001707 103.0
SHD3_k127_81608_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 323.0
SHD3_k127_81608_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001263 289.0
SHD3_k127_81608_4 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001129 246.0
SHD3_k127_81608_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009837 241.0
SHD3_k127_81608_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000005231 221.0
SHD3_k127_81608_7 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001306 226.0
SHD3_k127_81608_8 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000001071 210.0
SHD3_k127_81608_9 PFAM Peptidase family M20 M25 M40 K01436 - - 0.00000000000000000000000000000000000000000000291 181.0
SHD3_k127_816737_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.896e-235 750.0
SHD3_k127_816737_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.361e-219 705.0
SHD3_k127_816737_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000002168 200.0
SHD3_k127_816737_3 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000001244 120.0
SHD3_k127_816737_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000005552 111.0
SHD3_k127_816737_5 Protein of unknown function (DUF503) K09764 - - 0.0000000000000005129 81.0
SHD3_k127_816737_6 Zincin-like metallopeptidase - - - 0.00000000000004821 72.0
SHD3_k127_817038_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 503.0
SHD3_k127_817038_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002303 273.0
SHD3_k127_817038_2 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000004907 162.0
SHD3_k127_817038_3 - - - - 0.000000000000000000000000000000000003714 143.0
SHD3_k127_817038_4 Protein of unknown function (DUF3617) - - - 0.00003201 52.0
SHD3_k127_8613_0 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 357.0
SHD3_k127_8613_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001309 283.0
SHD3_k127_868956_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 393.0
SHD3_k127_868956_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 320.0
SHD3_k127_868956_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 320.0
SHD3_k127_868956_3 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000007697 126.0
SHD3_k127_868956_4 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000184 94.0
SHD3_k127_868956_5 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000002325 100.0
SHD3_k127_868956_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000006915 55.0
SHD3_k127_879261_0 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 610.0
SHD3_k127_879261_1 Gnat family - - - 0.0000000000000000000000000000000000000000006015 162.0
SHD3_k127_879261_2 epimerase K02377 - 1.1.1.271 0.000000000000000000000000000000000000001004 150.0
SHD3_k127_879261_3 epimerase K02377 - 1.1.1.271 0.00000000000000000000002291 102.0
SHD3_k127_879261_4 helix_turn_helix, Lux Regulon - - - 0.0000000000004361 79.0
SHD3_k127_882729_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 9.617e-219 700.0
SHD3_k127_882729_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 328.0
SHD3_k127_882729_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000006494 188.0
SHD3_k127_882729_3 - - - - 0.00000000000000000001613 104.0
SHD3_k127_919081_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001608 257.0
SHD3_k127_919081_1 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000006295 138.0
SHD3_k127_927969_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 409.0
SHD3_k127_927969_1 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001612 246.0
SHD3_k127_927969_2 synthase - - - 0.00000000000000000000001043 105.0
SHD3_k127_973852_0 chelatase, subunit ChlI K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 321.0
SHD3_k127_973852_1 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006545 266.0
SHD3_k127_979855_0 AMP-binding enzyme K01897 - 6.2.1.3 1.423e-213 683.0
SHD3_k127_979855_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 329.0
SHD3_k127_979855_2 lipoprotein localization to outer membrane K02004,K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001792 263.0
SHD3_k127_979855_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000001448 244.0
SHD3_k127_979855_4 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000003071 187.0
SHD3_k127_979855_5 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000002838 123.0
SHD3_k127_979855_6 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000001775 104.0
SHD3_k127_990876_0 YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 372.0
SHD3_k127_990876_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000002439 151.0
SHD3_k127_990876_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000005566 67.0
SHD3_k127_990876_3 PFAM blue (type 1) copper domain protein - - - 0.0006646 51.0