Overview

ID MAG03389
Name SHD3_bin.15
Sample SMP0084
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family Gemmatimonadaceae
Genus UBA4720
Species
Assembly information
Completeness (%) 81.86
Contamination (%) 4.09
GC content (%) 59.0
N50 (bp) 5,948
Genome size (bp) 2,937,319

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2828

Gene name Description KEGG GOs EC E-value Score Sequence
SHD3_k127_1014051_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 4.768e-233 733.0
SHD3_k127_1014051_1 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 561.0
SHD3_k127_1014051_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000208 252.0
SHD3_k127_1014051_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000001065 206.0
SHD3_k127_1026788_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 571.0
SHD3_k127_1026788_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001104 267.0
SHD3_k127_1026788_2 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000005698 216.0
SHD3_k127_1030662_0 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 486.0
SHD3_k127_1030662_1 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 479.0
SHD3_k127_1030662_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 348.0
SHD3_k127_1047701_0 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 488.0
SHD3_k127_1047701_1 Iron-sulfur cluster assembly protein - - - 0.000000000000003585 75.0
SHD3_k127_1053393_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.331e-247 774.0
SHD3_k127_1053393_1 - - - - 0.0000000000000001878 80.0
SHD3_k127_1053393_2 TonB-dependent Receptor Plug K16092 - - 0.000008002 54.0
SHD3_k127_108419_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002413 286.0
SHD3_k127_108419_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000427 243.0
SHD3_k127_108419_2 rRNA (adenine-N6,N6-)-dimethyltransferase activity K02528,K15256 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000005082 133.0
SHD3_k127_1090309_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 411.0
SHD3_k127_1090309_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 404.0
SHD3_k127_1090309_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 326.0
SHD3_k127_1119027_0 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 1.213e-250 790.0
SHD3_k127_1119027_1 Polysaccharide deacetylase - - - 0.0000000000000000000000003732 112.0
SHD3_k127_1124880_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 419.0
SHD3_k127_1124880_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000002561 216.0
SHD3_k127_1124880_2 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 0.0000000000000000000000000000000000000001068 151.0
SHD3_k127_114506_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 4.881e-210 666.0
SHD3_k127_114506_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 582.0
SHD3_k127_114506_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 394.0
SHD3_k127_114506_3 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 365.0
SHD3_k127_114506_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000342 244.0
SHD3_k127_114506_5 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000006475 166.0
SHD3_k127_114506_6 TatD family K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000001505 167.0
SHD3_k127_114506_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000001149 151.0
SHD3_k127_1147422_0 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 400.0
SHD3_k127_1147422_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 375.0
SHD3_k127_1147422_2 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000003934 240.0
SHD3_k127_1147422_3 DinB superfamily - - - 0.000000000000005618 82.0
SHD3_k127_1154303_0 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 556.0
SHD3_k127_1154303_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 557.0
SHD3_k127_1154303_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 543.0
SHD3_k127_1154303_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000003726 164.0
SHD3_k127_1154303_4 - - - - 0.0000000000000000000000000000000000988 135.0
SHD3_k127_1154303_5 - - - - 0.000000000000000000000000006322 113.0
SHD3_k127_1154303_6 - - - - 0.000000000000000001488 87.0
SHD3_k127_1163097_0 E1-E2 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 543.0
SHD3_k127_1163097_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 362.0
SHD3_k127_1163097_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000001865 136.0
SHD3_k127_1163097_3 Family of unknown function (DUF5335) - - - 0.0000000000000000000666 99.0
SHD3_k127_1164450_0 Heat shock 70 kDa protein K04043 - - 0.0 1071.0
SHD3_k127_1164450_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.168e-293 915.0
SHD3_k127_1164450_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 595.0
SHD3_k127_1164450_3 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 482.0
SHD3_k127_1164450_4 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 389.0
SHD3_k127_1164450_5 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 338.0
SHD3_k127_1164450_6 HAMP domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006292 283.0
SHD3_k127_1164450_7 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000004916 234.0
SHD3_k127_1166845_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 5.274e-257 800.0
SHD3_k127_1166845_1 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 545.0
SHD3_k127_1206612_0 Amidase K01426 - 3.5.1.4 5.798e-209 664.0
SHD3_k127_1206612_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000182 64.0
SHD3_k127_1211149_0 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 355.0
SHD3_k127_1211149_1 tRNA (guanine-N7-)-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000003121 202.0
SHD3_k127_1220648_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1261.0
SHD3_k127_1220648_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 556.0
SHD3_k127_1220648_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 540.0
SHD3_k127_1220648_3 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 536.0
SHD3_k127_1220648_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 512.0
SHD3_k127_1220648_5 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 361.0
SHD3_k127_1220648_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 325.0
SHD3_k127_1220648_7 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003558 248.0
SHD3_k127_1220648_8 Peptidase family M48 - - - 0.000000000000000000000000000000001199 132.0
SHD3_k127_1220648_9 - - - - 0.00000003456 64.0
SHD3_k127_1221255_0 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.0000000000000000000000000000000000000001055 162.0
SHD3_k127_1221255_1 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.00000000000000000000000000000000004182 138.0
SHD3_k127_1221255_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000003512 100.0
SHD3_k127_1221255_3 - - - - 0.0003166 44.0
SHD3_k127_1222233_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1477.0
SHD3_k127_1222233_1 ABC transporter transmembrane region K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 423.0
SHD3_k127_1222233_2 ABC transporter transmembrane region K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 322.0
SHD3_k127_1222233_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 309.0
SHD3_k127_1222233_4 Transglycosylase associated protein - - - 0.00000000000000000000000000215 115.0
SHD3_k127_1222233_5 Transglycosylase associated protein - - - 0.0000000000000000002326 90.0
SHD3_k127_1222233_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059,K07124 - 1.1.1.100 0.0000003243 53.0
SHD3_k127_1226207_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 587.0
SHD3_k127_1226207_1 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 293.0
SHD3_k127_1226207_2 Conserved hypothetical protein 95 K00564 - 2.1.1.172 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 299.0
SHD3_k127_1226207_3 endonuclease activity - - - 0.000000000000000000000000000000000000000000000005821 177.0
SHD3_k127_1226207_4 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000000007038 126.0
SHD3_k127_1226207_5 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000001243 115.0
SHD3_k127_1248029_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 548.0
SHD3_k127_1248029_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 520.0
SHD3_k127_1248029_2 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 426.0
SHD3_k127_1248029_3 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 357.0
SHD3_k127_1253362_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 531.0
SHD3_k127_1253362_1 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 309.0
SHD3_k127_1253362_2 peptidase K01415,K07386 - 3.4.24.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000001286 271.0
SHD3_k127_1253362_3 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000005575 187.0
SHD3_k127_1253362_4 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000002001 138.0
SHD3_k127_1264120_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000008991 235.0
SHD3_k127_1264120_1 allantoin biosynthetic process K01477,K16840 - 3.5.3.4,4.1.1.97 0.000000000000000000000000000000000000000000000769 172.0
SHD3_k127_1264120_2 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000003336 123.0
SHD3_k127_1264120_3 Belongs to the allantoicase family K01477 GO:0003674,GO:0003824,GO:0004037,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.3.4 0.0000002604 52.0
SHD3_k127_1292022_0 Major facilitator superfamily MFS_1 K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000003269 233.0
SHD3_k127_1292022_1 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000008355 192.0
SHD3_k127_1292022_2 Peptidase family M48 - - - 0.00000000000002755 76.0
SHD3_k127_130380_0 peptidase - - - 9.196e-211 669.0
SHD3_k127_130380_1 Rhodanese Homology Domain K01069,K03797 - 3.1.2.6,3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 586.0
SHD3_k127_130380_2 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 484.0
SHD3_k127_130380_3 Cytochrome b/b6/petB K00412,K03888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 331.0
SHD3_k127_130380_4 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008171 265.0
SHD3_k127_130380_5 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000009012 114.0
SHD3_k127_1308595_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 427.0
SHD3_k127_1308595_1 methylamine metabolic process K15977 - - 0.00000000000000000000000000000000000000000008788 165.0
SHD3_k127_1308595_2 DNA-binding transcription factor activity - - - 0.0000000000000000000005387 97.0
SHD3_k127_1313026_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.162e-199 629.0
SHD3_k127_1313026_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000004386 244.0
SHD3_k127_1313026_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000005184 191.0
SHD3_k127_1313026_3 - - - - 0.00000000000000000000000000000000000000000000000002126 182.0
SHD3_k127_1313026_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000002222 99.0
SHD3_k127_1318567_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 4.279e-231 723.0
SHD3_k127_1318567_1 Aromatic amino acid lyase K01745 - 4.3.1.3 5.53e-215 677.0
SHD3_k127_1318567_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.000000000000000001834 85.0
SHD3_k127_1322973_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 1.176e-203 676.0
SHD3_k127_1322973_1 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000009454 199.0
SHD3_k127_1322973_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01055 - 3.1.1.24 0.0000000000000006213 93.0
SHD3_k127_1344127_0 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 301.0
SHD3_k127_1344127_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000001026 240.0
SHD3_k127_1344127_2 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000006301 105.0
SHD3_k127_13527_0 Transport of potassium into the cell K03549 - - 3.473e-245 770.0
SHD3_k127_13527_1 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000001167 149.0
SHD3_k127_13527_2 S4 RNA-binding domain K04762 - - 0.00000000000000000000000000000000002883 139.0
SHD3_k127_13527_3 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000003154 106.0
SHD3_k127_1354759_0 peptidase K01415,K07386 - 3.4.24.71 8.043e-210 674.0
SHD3_k127_1354759_1 Aminotransferase class-V - - - 6.766e-198 624.0
SHD3_k127_1354759_2 Sugar (and other) transporter K07058 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 374.0
SHD3_k127_1354759_3 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000000005958 187.0
SHD3_k127_1354759_4 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000003497 160.0
SHD3_k127_1354759_5 DinB superfamily - - - 0.000000000000000000000000000001402 126.0
SHD3_k127_1373193_0 cellulose binding - - - 1.311e-273 851.0
SHD3_k127_1373193_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000006102 83.0
SHD3_k127_1437492_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 542.0
SHD3_k127_1437492_1 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 395.0
SHD3_k127_1437492_2 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 317.0
SHD3_k127_1437492_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 302.0
SHD3_k127_1437492_4 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000126 262.0
SHD3_k127_1437492_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000003925 213.0
SHD3_k127_1437492_6 STAS domain K04749 - - 0.00000000000000000000000000000000000000000000000000001926 190.0
SHD3_k127_1437492_7 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000001295 191.0
SHD3_k127_1437492_8 Arginine deiminase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000001125 196.0
SHD3_k127_1437492_9 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000000000000000002542 154.0
SHD3_k127_1438765_0 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004059 267.0
SHD3_k127_1438765_1 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000009766 244.0
SHD3_k127_1438765_2 Domain of unknown function (DUF4142) K08995 - - 0.000000000000000000000000000000000000000000000000000000006776 205.0
SHD3_k127_1438765_3 - - - - 0.000000000000000000000000000000000000000000001843 169.0
SHD3_k127_1438765_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000003198 160.0
SHD3_k127_1438765_5 - - - - 0.00000000000000000000000005235 112.0
SHD3_k127_145922_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 316.0
SHD3_k127_145922_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 300.0
SHD3_k127_145922_2 S4 RNA-binding domain K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 297.0
SHD3_k127_145922_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000002 130.0
SHD3_k127_1468337_0 Response regulator receiver domain K00384 - 1.8.1.9 3.016e-203 646.0
SHD3_k127_1468337_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005371 255.0
SHD3_k127_1471117_0 cyclic-guanylate-specific phosphodiesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 365.0
SHD3_k127_1471117_1 - - - - 0.00000000000004449 76.0
SHD3_k127_14817_0 secondary active sulfate transmembrane transporter activity - - - 1.991e-237 760.0
SHD3_k127_14817_1 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 306.0
SHD3_k127_14817_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000001647 201.0
SHD3_k127_14817_3 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000006885 113.0
SHD3_k127_14817_4 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000004889 104.0
SHD3_k127_14817_5 - - - - 0.0000000000000000000001791 108.0
SHD3_k127_14817_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000007569 59.0
SHD3_k127_1490583_0 Domain of unknown function (DUF4403) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 343.0
SHD3_k127_1490583_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000004996 183.0
SHD3_k127_1490583_2 Amino acid permease K03294 - - 0.000008338 49.0
SHD3_k127_1498415_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 3.311e-207 649.0
SHD3_k127_1498415_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 558.0
SHD3_k127_1498415_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 368.0
SHD3_k127_1498415_3 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 347.0
SHD3_k127_1498415_4 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000002639 133.0
SHD3_k127_1499261_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000379 230.0
SHD3_k127_1499261_1 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.0000000000000000000000000000000000000000000000000000000000000001552 235.0
SHD3_k127_1499261_2 glycosyl transferase family 2 - - - 0.0000000000000000000000000001006 128.0
SHD3_k127_1499261_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000003133 89.0
SHD3_k127_1511531_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000005941 205.0
SHD3_k127_1511531_1 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.0000000009134 71.0
SHD3_k127_1513203_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 1.797e-238 743.0
SHD3_k127_1513203_1 Glycosyl transferase 4-like domain K08256,K12995 - 2.4.1.345,2.4.1.348 0.00000000000000000000000000000000000000000000000000000000001354 217.0
SHD3_k127_1514231_0 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 582.0
SHD3_k127_1520816_0 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 389.0
SHD3_k127_1520816_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 297.0
SHD3_k127_1520816_2 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000000000565 205.0
SHD3_k127_1520816_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000001044 129.0
SHD3_k127_1520816_4 - - - - 0.00000000000000000000005162 101.0
SHD3_k127_1520816_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0004335 46.0
SHD3_k127_1536078_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1404.0
SHD3_k127_1536078_1 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 570.0
SHD3_k127_1536078_2 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 492.0
SHD3_k127_1536078_3 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000003964 218.0
SHD3_k127_1536078_4 4Fe-4S single cluster domain K07001 - - 0.0000000000000000000000000000000000000000000000000000006069 197.0
SHD3_k127_1536078_5 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000002529 184.0
SHD3_k127_1536078_6 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000001527 179.0
SHD3_k127_1536078_7 AntiSigma factor - - - 0.000000000000000000000000000000000000001262 158.0
SHD3_k127_1536078_8 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000003942 139.0
SHD3_k127_1536639_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 560.0
SHD3_k127_1536639_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 478.0
SHD3_k127_1536639_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 464.0
SHD3_k127_1536639_3 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 267.0
SHD3_k127_1536639_4 Glycine oxidase K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 0.0000000000000000000000000000000000000000000323 175.0
SHD3_k127_1536639_5 Glycosyl transferase family 2 K08301 - - 0.000000000000003879 78.0
SHD3_k127_1536639_6 - - - - 0.000000006119 60.0
SHD3_k127_153670_0 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 323.0
SHD3_k127_153670_1 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 305.0
SHD3_k127_153670_2 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006712 278.0
SHD3_k127_1543945_0 MatE - - - 1.667e-203 646.0
SHD3_k127_1543945_1 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 428.0
SHD3_k127_1543945_2 nucleotide-excision repair K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 378.0
SHD3_k127_1543945_3 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004734 239.0
SHD3_k127_1548092_0 cellular response to dsDNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002537 264.0
SHD3_k127_1548092_1 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000001468 160.0
SHD3_k127_1548092_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000007745 126.0
SHD3_k127_1548092_3 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000442 123.0
SHD3_k127_155203_0 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 3.134e-206 646.0
SHD3_k127_155203_1 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000003212 224.0
SHD3_k127_155203_2 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001368 218.0
SHD3_k127_155203_3 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000006721 105.0
SHD3_k127_1554027_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.705e-256 797.0
SHD3_k127_1554027_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 393.0
SHD3_k127_1554027_2 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002523 252.0
SHD3_k127_1554027_3 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000009486 152.0
SHD3_k127_1572867_0 ABC transporter K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 319.0
SHD3_k127_1572867_1 thiamine transport K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001269 282.0
SHD3_k127_1603130_0 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 540.0
SHD3_k127_1603130_1 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000002185 211.0
SHD3_k127_1603130_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000001503 59.0
SHD3_k127_1603530_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.577e-251 786.0
SHD3_k127_1603530_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 5.312e-251 786.0
SHD3_k127_1603530_10 Regulatory protein, FmdB family - - - 0.00000000000001651 79.0
SHD3_k127_1603530_11 - - - - 0.0005415 48.0
SHD3_k127_1603530_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.394e-217 683.0
SHD3_k127_1603530_3 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 589.0
SHD3_k127_1603530_4 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 562.0
SHD3_k127_1603530_5 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 496.0
SHD3_k127_1603530_6 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 467.0
SHD3_k127_1603530_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000001216 269.0
SHD3_k127_1603530_8 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000005755 132.0
SHD3_k127_1616221_0 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 422.0
SHD3_k127_1616221_1 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000001403 179.0
SHD3_k127_1616221_2 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.000000000000000005225 90.0
SHD3_k127_1616221_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000002278 91.0
SHD3_k127_1616221_4 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.0000000000000002947 85.0
SHD3_k127_1616221_5 Glycosyl transferases group 1 - - - 0.0000000000000004271 81.0
SHD3_k127_1616221_6 Glycosyl transferase 4-like domain K08256,K12995 - 2.4.1.345,2.4.1.348 0.000000000002118 71.0
SHD3_k127_161954_0 cellulose binding - - - 0.0 1019.0
SHD3_k127_161954_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 399.0
SHD3_k127_161954_2 transcriptional regulators - - - 0.00000000000000000001939 97.0
SHD3_k127_16209_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 486.0
SHD3_k127_16209_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 365.0
SHD3_k127_16209_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000008161 222.0
SHD3_k127_16209_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000001754 216.0
SHD3_k127_16209_4 COGs COG2311 membrane protein K07148 - - 0.00000000000000000000511 100.0
SHD3_k127_16209_5 Ribosomal protein L36 K02919 - - 0.000000000000002337 76.0
SHD3_k127_1626656_0 Sodium:dicarboxylate symporter family K11102 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 456.0
SHD3_k127_1626656_1 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001766 269.0
SHD3_k127_1644109_0 Glucose inhibited division protein A K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 447.0
SHD3_k127_1644109_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000001829 55.0
SHD3_k127_1653756_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 607.0
SHD3_k127_1653756_1 - - - - 0.00005384 48.0
SHD3_k127_1664587_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 2.748e-263 842.0
SHD3_k127_1664587_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001202 275.0
SHD3_k127_1664587_2 Outer membrane lipoprotein - - - 0.00000000000001006 76.0
SHD3_k127_1665606_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 563.0
SHD3_k127_1665606_1 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 450.0
SHD3_k127_1665606_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 442.0
SHD3_k127_1665606_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 406.0
SHD3_k127_1665606_4 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 300.0
SHD3_k127_1665606_5 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000004147 229.0
SHD3_k127_1665606_6 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000007593 205.0
SHD3_k127_1679836_0 Acts as a magnesium transporter K06213 - - 1.315e-194 619.0
SHD3_k127_1679836_1 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 305.0
SHD3_k127_1679836_2 acyl-CoA dehydrogenase - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000001705 134.0
SHD3_k127_1679836_3 haemagglutination activity domain - - - 0.0000000002549 70.0
SHD3_k127_1679836_4 mercury ion transmembrane transporter activity K07213 - - 0.0000004094 57.0
SHD3_k127_1679836_5 Dystroglycan-type cadherin-like domains. - - - 0.000004022 58.0
SHD3_k127_1694455_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1073.0
SHD3_k127_1694455_1 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 323.0
SHD3_k127_1711165_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 342.0
SHD3_k127_1711165_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 333.0
SHD3_k127_1715118_0 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 368.0
SHD3_k127_1715118_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000007887 246.0
SHD3_k127_1715118_2 Thioredoxin-like domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000003252 200.0
SHD3_k127_1715118_3 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000003656 195.0
SHD3_k127_1715118_4 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.000000000000000008308 87.0
SHD3_k127_1715118_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000002139 91.0
SHD3_k127_1715118_7 - - - - 0.00009187 53.0
SHD3_k127_1715118_8 - - - - 0.0002103 45.0
SHD3_k127_1718686_0 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 340.0
SHD3_k127_1718686_1 transferase activity, transferring glycosyl groups K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 319.0
SHD3_k127_1718686_2 PFAM Glycosyl transferase family 4 K02851,K13007 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 306.0
SHD3_k127_1718686_3 PFAM NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000001716 226.0
SHD3_k127_1718686_4 O-antigen polysaccharide polymerase Wzy - - - 0.0000000000000000000000000001488 131.0
SHD3_k127_1718686_5 Capsule assembly protein Wzi - - - 0.0000000000000000000001258 108.0
SHD3_k127_1718686_6 extracellular polysaccharide biosynthetic process K16554,K21473 - - 0.00000000000004952 84.0
SHD3_k127_1718686_7 Glycosyltransferase like family 2 - - - 0.0000000003726 66.0
SHD3_k127_1724511_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 2801.0
SHD3_k127_1724511_1 PFAM FAD dependent oxidoreductase - - - 2.924e-204 648.0
SHD3_k127_1724511_2 Putative glucoamylase K13688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 350.0
SHD3_k127_1746006_0 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 374.0
SHD3_k127_1746006_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 349.0
SHD3_k127_1746006_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 299.0
SHD3_k127_1746006_3 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000009295 249.0
SHD3_k127_1746006_4 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000004474 202.0
SHD3_k127_1746006_5 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000002201 176.0
SHD3_k127_1746006_6 DinB family - - - 0.000000000000000000000000000000000000005975 151.0
SHD3_k127_1746006_7 impB/mucB/samB family - - - 0.0000000002822 72.0
SHD3_k127_1753689_0 Zinc carboxypeptidase K14054 - - 0.0 1192.0
SHD3_k127_1753689_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001765 256.0
SHD3_k127_1753689_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000001887 226.0
SHD3_k127_1754934_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 509.0
SHD3_k127_1754934_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 462.0
SHD3_k127_1754934_2 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004254 273.0
SHD3_k127_1756737_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.399e-292 917.0
SHD3_k127_1756737_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 590.0
SHD3_k127_1756737_10 Roadblock/LC7 domain K07131 - - 0.000000000000000000000002551 106.0
SHD3_k127_1756737_11 - - - - 0.00000000000000000000001985 113.0
SHD3_k127_1756737_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 586.0
SHD3_k127_1756737_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 525.0
SHD3_k127_1756737_4 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 452.0
SHD3_k127_1756737_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 412.0
SHD3_k127_1756737_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000002985 186.0
SHD3_k127_1756737_7 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000002076 155.0
SHD3_k127_1756737_8 Sugar nucleotidyl transferase - - - 0.000000000000000000000000000000000000003046 153.0
SHD3_k127_1756737_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000001941 106.0
SHD3_k127_1763089_0 Alpha amylase - - - 0.0 1305.0
SHD3_k127_1763089_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000002571 214.0
SHD3_k127_1767153_0 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 3.79e-227 736.0
SHD3_k127_1767153_1 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 624.0
SHD3_k127_1767153_2 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002235 303.0
SHD3_k127_1772045_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 302.0
SHD3_k127_1772045_1 - - - - 0.00000000000000000000000000000000000001407 153.0
SHD3_k127_1772045_2 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000006364 130.0
SHD3_k127_177592_0 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 538.0
SHD3_k127_177592_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000003969 212.0
SHD3_k127_177592_2 amino acid - - - 0.000000000000000000000000000000000000000000003921 175.0
SHD3_k127_177592_3 - - - - 0.000000000000000000000000000000000000000002786 160.0
SHD3_k127_177592_4 Acetoacetate metabolism regulatory protein atoC K02481 - - 0.000003529 51.0
SHD3_k127_1784555_0 hydroxymethylglutaryl-CoA reductase K00021 - 1.1.1.34 5.334e-209 679.0
SHD3_k127_1784555_1 dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 512.0
SHD3_k127_1784555_2 Protein of unknown function (DUF3419) - - - 0.00000000000000000000000000000000000000000000000000000000000000001033 240.0
SHD3_k127_1784555_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000005734 224.0
SHD3_k127_1784555_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000002283 181.0
SHD3_k127_1784555_5 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000001239 184.0
SHD3_k127_1784555_6 PFAM AMP-dependent synthetase and ligase K22319 - 6.1.3.1 0.000000000000000000000000000000000000000000000118 187.0
SHD3_k127_1794889_0 iron-nicotianamine transmembrane transporter activity - - - 1.149e-195 623.0
SHD3_k127_1794889_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000001024 200.0
SHD3_k127_1794889_2 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000008601 198.0
SHD3_k127_1794889_3 - - - - 0.00000000000000000000000000000000000000000000003664 185.0
SHD3_k127_1794889_4 - - - - 0.00000000000000000000000000000000000000000000006062 177.0
SHD3_k127_1794889_5 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000003846 90.0
SHD3_k127_1795790_0 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 436.0
SHD3_k127_1795790_1 Transferase activity, transferring acyl groups other than amino-acyl groups. It is involved in the biological process described with metabolic process K07508,K17972 GO:0001666,GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006066,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006915,GO:0006950,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008219,GO:0008610,GO:0008637,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009628,GO:0009966,GO:0009968,GO:0009987,GO:0010639,GO:0010646,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0012501,GO:0016042,GO:0016043,GO:0016054,GO:0016125,GO:0016126,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0023051,GO:0023057,GO:0030258,GO:0031974,GO:0032787,GO:0032879,GO:0033043,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0035795,GO:0036293,GO:0036294,GO:0042221,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046395,GO:0046483,GO:0046902,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051186,GO:0051234,GO:0051716,GO:0055086,GO:0055114,GO:0060548,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0090559,GO:1901028,GO:1901029,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902108,GO:1902109,GO:1902652,GO:1902653,GO:1905709,GO:2001233,GO:2001234 2.3.1.16,2.3.1.254 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 398.0
SHD3_k127_1795790_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 332.0
SHD3_k127_1795790_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000002753 248.0
SHD3_k127_1795790_4 - - - - 0.000000000000000000000000000000002063 139.0
SHD3_k127_1795790_5 - - - - 0.00000000002599 66.0
SHD3_k127_1812630_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 598.0
SHD3_k127_1812630_1 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 384.0
SHD3_k127_1812630_10 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.0000000000000000000000000000000001383 145.0
SHD3_k127_1812630_11 sequence-specific DNA binding K07729 - - 0.000000000000007458 81.0
SHD3_k127_1812630_12 methyltransferase activity - - - 0.0000000000003546 75.0
SHD3_k127_1812630_13 - - - - 0.000000002629 63.0
SHD3_k127_1812630_15 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00009787 45.0
SHD3_k127_1812630_2 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001258 280.0
SHD3_k127_1812630_3 Clp amino terminal domain, pathogenicity island component K03696 - - 0.000000000000000000000000000000000000000000000009698 175.0
SHD3_k127_1812630_4 - K01865 - 5.4.4.1 0.0000000000000000000000000000000000000000000001329 175.0
SHD3_k127_1812630_5 - - - - 0.0000000000000000000000000000000000000000000009075 173.0
SHD3_k127_1812630_6 Membrane protein involved in cytochrome C biogenesis - - - 0.00000000000000000000000000000000000000002808 158.0
SHD3_k127_1812630_7 - - - - 0.0000000000000000000000000000000000000005848 151.0
SHD3_k127_1812630_8 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000000002591 149.0
SHD3_k127_1812630_9 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000005596 151.0
SHD3_k127_1813282_0 DALR_2 K01883 - 6.1.1.16 2.019e-206 651.0
SHD3_k127_1813282_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000001367 98.0
SHD3_k127_182002_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 562.0
SHD3_k127_182002_1 - - - - 0.0000000000000000000000000000000000000001285 162.0
SHD3_k127_182002_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000004524 78.0
SHD3_k127_1831300_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 579.0
SHD3_k127_1831300_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000003397 253.0
SHD3_k127_1831300_3 acr, cog1993 K09137 - - 0.0000000000000000000000000000000000000000001383 163.0
SHD3_k127_1831300_4 acr, cog1993 K09137 - - 0.000000000000000000000000000000000001575 141.0
SHD3_k127_1831300_5 Pyridoxamine 5'-phosphate oxidase like - - - 0.00000000000000000000000000003991 123.0
SHD3_k127_1831300_6 Capsule assembly protein Wzi - - - 0.0000000000000000000002201 112.0
SHD3_k127_1831300_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000004143 67.0
SHD3_k127_1831366_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.085e-200 633.0
SHD3_k127_1831366_1 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 366.0
SHD3_k127_1831366_2 - - - - 0.0000000000004334 80.0
SHD3_k127_1831366_3 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000004745 62.0
SHD3_k127_1832944_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 404.0
SHD3_k127_1832944_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000002357 166.0
SHD3_k127_1832944_2 Glycosyltransferase, group 2 family protein - - - 0.0000000000000000000000000001193 123.0
SHD3_k127_1835195_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1084.0
SHD3_k127_1844814_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 426.0
SHD3_k127_1844814_1 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 391.0
SHD3_k127_1844814_2 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 329.0
SHD3_k127_1844814_3 Transport of potassium into the cell K03549 - - 0.000000000000000000009978 93.0
SHD3_k127_1844814_5 - - - - 0.0005322 47.0
SHD3_k127_1855199_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 300.0
SHD3_k127_1855199_1 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000000000000000000000000000000000000000000006392 214.0
SHD3_k127_1855199_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000173 190.0
SHD3_k127_1859798_0 Sigma factor PP2C-like phosphatases - - - 5.872e-210 669.0
SHD3_k127_1859798_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000004556 142.0
SHD3_k127_1859798_2 - - - - 0.00000000000000000000000000000007137 132.0
SHD3_k127_1859798_3 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase - - - 0.0000000000000000000001867 100.0
SHD3_k127_1859798_4 Sigma-70, region 4 K03088 - - 0.0000000000000000000004486 99.0
SHD3_k127_1863527_0 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 362.0
SHD3_k127_1863527_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001559 271.0
SHD3_k127_1863527_2 Histidine kinase - - - 0.00000000000000000004238 104.0
SHD3_k127_1873444_0 amine dehydrogenase activity K17285 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 353.0
SHD3_k127_1873444_2 (ABC) transporter - - - 0.000000236 52.0
SHD3_k127_1891011_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 432.0
SHD3_k127_1891011_1 EXOIII K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004939 285.0
SHD3_k127_1891011_2 arginine K01478 - 3.5.3.6 0.0000002499 53.0
SHD3_k127_1900453_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 6.645e-205 647.0
SHD3_k127_1900453_1 4Fe-4S binding domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 574.0
SHD3_k127_1900453_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 475.0
SHD3_k127_1900453_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 366.0
SHD3_k127_1900453_4 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 305.0
SHD3_k127_1900453_5 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005662 287.0
SHD3_k127_1900453_6 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003215 266.0
SHD3_k127_1900453_7 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000326 226.0
SHD3_k127_1900453_8 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000002991 166.0
SHD3_k127_1900453_9 3D domain protein - - - 0.0000000000000000000000000000000000004821 148.0
SHD3_k127_1903685_0 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 377.0
SHD3_k127_1903685_1 photoreceptor activity K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 381.0
SHD3_k127_1903685_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000006245 184.0
SHD3_k127_1903685_3 Predicted membrane protein (DUF2127) - - - 0.00000000000000000000000000000002955 132.0
SHD3_k127_1903685_4 - - - - 0.0000000000000005238 85.0
SHD3_k127_1906153_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 366.0
SHD3_k127_1906153_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 308.0
SHD3_k127_1906153_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000002552 155.0
SHD3_k127_1906153_3 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000002371 145.0
SHD3_k127_1906153_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000003818 119.0
SHD3_k127_1906153_5 BON domain K04065 - - 0.0000000006952 70.0
SHD3_k127_1927860_0 Protein export membrane protein - - - 0.0 1556.0
SHD3_k127_1927860_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 437.0
SHD3_k127_1927860_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 387.0
SHD3_k127_1927860_3 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 326.0
SHD3_k127_1927860_4 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000004646 158.0
SHD3_k127_1927860_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000009957 124.0
SHD3_k127_1927860_6 Protein of unknown function (DUF2892) - - - 0.000000000000000000000004297 104.0
SHD3_k127_1927860_7 - - - - 0.000000000000000247 85.0
SHD3_k127_1939897_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 602.0
SHD3_k127_1939897_1 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 488.0
SHD3_k127_1939897_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 481.0
SHD3_k127_1939897_3 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 392.0
SHD3_k127_1939897_4 ABC transporter transmembrane region K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 287.0
SHD3_k127_1939897_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002954 286.0
SHD3_k127_1939897_6 - - - - 0.00000000000000374 84.0
SHD3_k127_1939897_7 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000009685 55.0
SHD3_k127_1942375_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000003009 154.0
SHD3_k127_1942375_1 xylanase chitin deacetylase - - - 0.000000000000000000000000002284 126.0
SHD3_k127_1942375_2 Carbamoyltransferase C-terminus K00612 - - 0.00000000000000000001138 107.0
SHD3_k127_1942375_3 SAM-utilizing methyltransferase involved in nod factor synthesis - - - 0.0003865 49.0
SHD3_k127_1945809_0 glucan 1,4-alpha-glucosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 362.0
SHD3_k127_1947291_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 390.0
SHD3_k127_1947291_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 317.0
SHD3_k127_1947291_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000006323 55.0
SHD3_k127_1957834_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1080.0
SHD3_k127_1957834_1 4Fe-4S binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 379.0
SHD3_k127_1957834_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 390.0
SHD3_k127_1957834_3 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 380.0
SHD3_k127_1957834_4 - K00241 - - 0.0000005554 51.0
SHD3_k127_19629_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 369.0
SHD3_k127_19629_1 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.00000000000000000000000000000000000000000000002641 173.0
SHD3_k127_19629_2 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000001325 103.0
SHD3_k127_1967976_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.265e-263 818.0
SHD3_k127_1967976_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.17e-238 749.0
SHD3_k127_1967976_10 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 321.0
SHD3_k127_1967976_11 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005699 273.0
SHD3_k127_1967976_12 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000005998 233.0
SHD3_k127_1967976_13 Lysine methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000008423 220.0
SHD3_k127_1967976_14 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000486 204.0
SHD3_k127_1967976_15 - - - - 0.00000000000000000000000000000000000000000000000000000002802 204.0
SHD3_k127_1967976_16 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000000161 164.0
SHD3_k127_1967976_17 - - - - 0.0000000000000000000000000000004152 131.0
SHD3_k127_1967976_18 - - - - 0.000000000000000000000001344 111.0
SHD3_k127_1967976_2 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 8.39e-209 662.0
SHD3_k127_1967976_3 C-terminus of AA_permease K03294 - - 2.72e-208 659.0
SHD3_k127_1967976_4 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 477.0
SHD3_k127_1967976_5 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 415.0
SHD3_k127_1967976_6 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 405.0
SHD3_k127_1967976_7 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 346.0
SHD3_k127_1967976_8 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 337.0
SHD3_k127_1967976_9 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 320.0
SHD3_k127_2000488_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.524e-262 818.0
SHD3_k127_2000488_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 492.0
SHD3_k127_2002336_0 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 459.0
SHD3_k127_2002336_1 PFAM bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001106 278.0
SHD3_k127_2002336_2 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002549 248.0
SHD3_k127_2002336_3 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008595 238.0
SHD3_k127_2002336_4 PFAM DNA RNA tunnel of bacterial DNA dependent RNA polymerase - - - 0.000000000000000000000000000000000000000000000000000001429 194.0
SHD3_k127_2002336_5 lactoylglutathione lyase activity - - - 0.0000000000000000000000000004383 117.0
SHD3_k127_2002336_6 Ricin-type beta-trefoil - - - 0.000000001476 70.0
SHD3_k127_2030351_0 Peptidase M14, carboxypeptidase A - - - 1.182e-265 833.0
SHD3_k127_2030351_1 PFAM glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 342.0
SHD3_k127_2030351_2 HNH nucleases - - - 0.0000000000006159 76.0
SHD3_k127_203506_0 Peptidase dimerisation domain - - - 1.438e-195 621.0
SHD3_k127_203506_1 COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 476.0
SHD3_k127_203506_2 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 421.0
SHD3_k127_203506_3 glycosyl hydrolase - - - 0.0000000000000000000000000000003992 126.0
SHD3_k127_2041031_0 Nucleoside H+ symporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 456.0
SHD3_k127_2041031_1 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003347 245.0
SHD3_k127_2049675_0 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 366.0
SHD3_k127_2049675_1 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000000000000000002174 136.0
SHD3_k127_2064767_0 PFAM Enoyl-CoA hydratase isomerase - - - 1.337e-225 719.0
SHD3_k127_2064767_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 610.0
SHD3_k127_2064767_2 benzoyl-CoA reductase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 424.0
SHD3_k127_2064767_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000003967 91.0
SHD3_k127_2072453_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 465.0
SHD3_k127_2072453_1 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000000004703 166.0
SHD3_k127_2104867_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1301.0
SHD3_k127_2104867_1 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 382.0
SHD3_k127_2104867_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 379.0
SHD3_k127_2104867_3 Rhomboid family - - - 0.000000000000000000000000002506 112.0
SHD3_k127_2113601_0 CarboxypepD_reg-like domain - - - 4.599e-222 730.0
SHD3_k127_2113601_1 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 331.0
SHD3_k127_2113601_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 322.0
SHD3_k127_2113601_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 309.0
SHD3_k127_2113601_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000001042 99.0
SHD3_k127_2113601_5 Amino acid permease K03294 - - 0.000000000000002088 76.0
SHD3_k127_2114068_0 HELICc2 K03722 - 3.6.4.12 1.187e-267 844.0
SHD3_k127_2114068_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008034 282.0
SHD3_k127_2114068_2 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000331 212.0
SHD3_k127_2114068_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000113 116.0
SHD3_k127_2149155_0 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 557.0
SHD3_k127_2149155_1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000002828 262.0
SHD3_k127_2149155_2 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000001951 197.0
SHD3_k127_214944_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 567.0
SHD3_k127_214944_1 Belongs to the allantoicase family K01477 GO:0003674,GO:0003824,GO:0004037,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 468.0
SHD3_k127_214944_2 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.00000000002812 64.0
SHD3_k127_2150626_0 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 586.0
SHD3_k127_2150626_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000879 45.0
SHD3_k127_2154909_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 372.0
SHD3_k127_2154909_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008348 254.0
SHD3_k127_2154909_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000124 177.0
SHD3_k127_2155105_0 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 432.0
SHD3_k127_2155105_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 337.0
SHD3_k127_2155105_2 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001126 265.0
SHD3_k127_2155105_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000001156 203.0
SHD3_k127_2155105_4 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000001878 137.0
SHD3_k127_2155105_5 Belongs to the ompA family K03286 - - 0.00007344 45.0
SHD3_k127_2155105_6 Major facilitator Superfamily - - - 0.0002962 43.0
SHD3_k127_2156581_0 Insulinase (Peptidase family M16) K07263 - - 1.458e-273 872.0
SHD3_k127_2156581_1 cytochrome C peroxidase - - - 8.073e-247 780.0
SHD3_k127_2156581_10 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000000004491 106.0
SHD3_k127_2156581_11 Putative adhesin - - - 0.00000000000000000001955 99.0
SHD3_k127_2156581_12 Domain of unknown function (DUF4342) - - - 0.0000000000000005708 81.0
SHD3_k127_2156581_2 Sodium:dicarboxylate symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 357.0
SHD3_k127_2156581_3 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002039 249.0
SHD3_k127_2156581_4 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007661 240.0
SHD3_k127_2156581_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002395 243.0
SHD3_k127_2156581_6 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000008328 205.0
SHD3_k127_2156581_7 - - - - 0.00000000000000000000000000000000000000000000000000004402 198.0
SHD3_k127_2158405_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0 1235.0
SHD3_k127_2158405_1 Cbb3-type cytochrome oxidase K00407 - - 0.00005102 52.0
SHD3_k127_2158405_2 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0008002 42.0
SHD3_k127_216130_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.827e-210 661.0
SHD3_k127_216130_1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 392.0
SHD3_k127_216130_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000108 201.0
SHD3_k127_216130_3 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000001598 168.0
SHD3_k127_216130_4 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000003082 145.0
SHD3_k127_216130_5 Glycosyltransferase, group 2 family protein - - - 0.0000000000000000002769 93.0
SHD3_k127_21616_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 422.0
SHD3_k127_21616_1 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000002124 127.0
SHD3_k127_21616_2 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000007374 117.0
SHD3_k127_2171633_0 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 475.0
SHD3_k127_2171633_1 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000154 239.0
SHD3_k127_2171633_2 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004931 245.0
SHD3_k127_2171633_3 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000002131 239.0
SHD3_k127_2171633_4 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000000000001422 186.0
SHD3_k127_2171633_5 - - - - 0.00000000000000000000000000000000000001316 147.0
SHD3_k127_2171633_6 Zinc carboxypeptidase - - - 0.0000000002128 67.0
SHD3_k127_2174238_0 iron-nicotianamine transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 597.0
SHD3_k127_2175008_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 387.0
SHD3_k127_2175008_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005998 270.0
SHD3_k127_2175008_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000001831 206.0
SHD3_k127_2175008_3 - - - - 0.0000000000000000000000000000000000000000000000007853 184.0
SHD3_k127_2203088_0 alginic acid biosynthetic process - - - 5.097e-230 736.0
SHD3_k127_2203088_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 6.386e-199 629.0
SHD3_k127_2203088_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 520.0
SHD3_k127_2203088_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000009609 168.0
SHD3_k127_2203088_4 Peptidase family M23 K21472 - - 0.0000000000000000000000000000000000000000001173 166.0
SHD3_k127_2203088_5 CRS1_YhbY K07574 - - 0.00000000000000000000000000000000001041 138.0
SHD3_k127_2203088_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000004533 126.0
SHD3_k127_2203088_7 Domain of unknown function (DUF4918) - - - 0.00009998 48.0
SHD3_k127_2214640_0 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 330.0
SHD3_k127_2214640_1 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01911 - 6.2.1.26 0.000000000000000000000000000000000000000008752 160.0
SHD3_k127_2232214_0 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 390.0
SHD3_k127_2232214_1 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 380.0
SHD3_k127_2232214_2 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000002331 115.0
SHD3_k127_2238990_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 6.126e-225 704.0
SHD3_k127_2238990_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 457.0
SHD3_k127_2238990_2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001399 267.0
SHD3_k127_2246478_0 Arginine deiminase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000008685 182.0
SHD3_k127_2246478_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000003305 115.0
SHD3_k127_2246478_2 Amidinotransferase K01478 - 3.5.3.6 0.00000000000000000000005336 100.0
SHD3_k127_2246478_3 EXOIII K02342 - 2.7.7.7 0.0000000000000000000008861 101.0
SHD3_k127_2262427_0 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 346.0
SHD3_k127_2262427_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 302.0
SHD3_k127_2262427_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000005353 215.0
SHD3_k127_2262427_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000007948 203.0
SHD3_k127_2262427_4 - - - - 0.00000000000000000006107 98.0
SHD3_k127_2262427_5 Thioredoxin-like domain K03671 - - 0.00000000000000002737 81.0
SHD3_k127_2262427_6 - - - - 0.0000000004152 66.0
SHD3_k127_2264296_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.823e-314 969.0
SHD3_k127_2264296_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.301e-302 947.0
SHD3_k127_2264296_10 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000001473 223.0
SHD3_k127_2264296_11 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000003497 207.0
SHD3_k127_2264296_12 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000001146 196.0
SHD3_k127_2264296_13 - - - - 0.00000000000000000000000000000000000000000000000006852 185.0
SHD3_k127_2264296_14 Lipopolysaccharide kinase (Kdo/WaaP) family K11211 - 2.7.1.166 0.0000000000000000000000000000000000000000006477 167.0
SHD3_k127_2264296_15 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000006882 153.0
SHD3_k127_2264296_2 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 1.587e-217 685.0
SHD3_k127_2264296_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 1.078e-205 648.0
SHD3_k127_2264296_4 - - - - 7.962e-204 655.0
SHD3_k127_2264296_5 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 476.0
SHD3_k127_2264296_6 O-acyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 419.0
SHD3_k127_2264296_7 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 423.0
SHD3_k127_2264296_8 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 389.0
SHD3_k127_2264296_9 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001507 270.0
SHD3_k127_2279825_0 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 415.0
SHD3_k127_2279825_1 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 362.0
SHD3_k127_2279825_2 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 360.0
SHD3_k127_2279825_3 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001771 280.0
SHD3_k127_2279825_4 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000001372 123.0
SHD3_k127_229309_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1122.0
SHD3_k127_229309_1 Peptidase family M49 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 349.0
SHD3_k127_2298304_0 Di- and tricarboxylate transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 363.0
SHD3_k127_2298304_1 Phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001358 267.0
SHD3_k127_2298304_2 CYTH K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000002521 209.0
SHD3_k127_2298304_3 Ppx/GppA phosphatase family - - - 0.0000000000000000000000000001144 125.0
SHD3_k127_2307920_0 Amidase K02433 - 6.3.5.6,6.3.5.7 5.647e-241 752.0
SHD3_k127_2316923_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 493.0
SHD3_k127_2316923_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 391.0
SHD3_k127_2316923_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000001951 236.0
SHD3_k127_2316923_3 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000005412 214.0
SHD3_k127_2316923_4 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000000000000000000000000000000000006602 187.0
SHD3_k127_2316923_5 - - - - 0.0000000000000000000000000000000000000001044 157.0
SHD3_k127_2316923_6 crp fnr family K21564 - - 0.00008953 53.0
SHD3_k127_2320121_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 1.537e-239 763.0
SHD3_k127_2320121_1 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 355.0
SHD3_k127_2320121_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000288 177.0
SHD3_k127_2320121_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000006561 125.0
SHD3_k127_2325423_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.106e-295 911.0
SHD3_k127_2325423_1 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 527.0
SHD3_k127_2325423_10 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000008253 175.0
SHD3_k127_2325423_11 Lipopolysaccharide-assembly, LptC-related - - - 0.00000000000000000000000000000000000000001105 161.0
SHD3_k127_2325423_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000001194 139.0
SHD3_k127_2325423_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 467.0
SHD3_k127_2325423_3 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 408.0
SHD3_k127_2325423_4 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 390.0
SHD3_k127_2325423_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006578 293.0
SHD3_k127_2325423_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001757 285.0
SHD3_k127_2325423_7 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000126 282.0
SHD3_k127_2325423_9 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000001778 219.0
SHD3_k127_2329882_0 ABC transporter C-terminal domain K15738 - - 3.819e-266 832.0
SHD3_k127_2329882_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 473.0
SHD3_k127_2329882_2 ABC-2 family transporter protein K01992 - - 0.0000002405 54.0
SHD3_k127_2334196_0 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000000003043 218.0
SHD3_k127_2334196_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000003637 166.0
SHD3_k127_2334196_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000636 66.0
SHD3_k127_2337345_0 Insulinase (Peptidase family M16) K07263 - - 2.76e-321 1005.0
SHD3_k127_2337345_1 Amidohydrolase family - - - 2.213e-243 768.0
SHD3_k127_2337345_2 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 343.0
SHD3_k127_2337345_3 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000176 88.0
SHD3_k127_2343680_0 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002821 282.0
SHD3_k127_2343680_1 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000113 196.0
SHD3_k127_234420_0 Domain of unknown function (DUF5118) - - - 1.247e-211 670.0
SHD3_k127_234420_1 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000001708 185.0
SHD3_k127_2345677_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 339.0
SHD3_k127_2345677_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 312.0
SHD3_k127_2345677_2 Histidine kinase - - - 0.000000000000000000000002465 107.0
SHD3_k127_2346248_0 Fumarase C C-terminus K01744 - 4.3.1.1 3.505e-231 725.0
SHD3_k127_2346248_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000009606 241.0
SHD3_k127_2346248_2 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000008152 211.0
SHD3_k127_2346248_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000002959 88.0
SHD3_k127_2346248_4 Ami_3 K01448 - 3.5.1.28 0.000000000000007218 80.0
SHD3_k127_2346457_0 Cytidylate kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000003085 201.0
SHD3_k127_2346457_1 Transcription factor zinc-finger K09981 - - 0.0000000000000000000001007 101.0
SHD3_k127_2346457_2 - - - - 0.000000000000000000001243 100.0
SHD3_k127_2375904_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 442.0
SHD3_k127_2375904_1 Cardiolipin synthetase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 346.0
SHD3_k127_2375904_2 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001203 259.0
SHD3_k127_2375904_3 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000004237 121.0
SHD3_k127_2377205_0 DNA restriction-modification system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 328.0
SHD3_k127_2377205_1 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 323.0
SHD3_k127_2379170_0 Mur ligase family, glutamate ligase domain K03802 - 6.3.2.29,6.3.2.30 2.288e-246 788.0
SHD3_k127_2379170_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 416.0
SHD3_k127_2379170_2 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000008548 211.0
SHD3_k127_2379170_3 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K03802 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000002363 131.0
SHD3_k127_2379170_4 PFAM S23 ribosomal protein - - - 0.0000001529 59.0
SHD3_k127_2379170_5 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.0001724 51.0
SHD3_k127_2394953_0 von Willebrand factor (vWF) type A domain - - - 2.334e-209 655.0
SHD3_k127_2394953_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 549.0
SHD3_k127_2394953_2 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 471.0
SHD3_k127_2394953_3 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000001206 142.0
SHD3_k127_2394953_4 Copper resistance protein CopC K14166 - - 0.000000000000000001652 99.0
SHD3_k127_2394953_5 protein kinase activity - - - 0.0000003437 59.0
SHD3_k127_2397873_0 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 362.0
SHD3_k127_2397873_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000142 92.0
SHD3_k127_2403233_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 404.0
SHD3_k127_2403233_1 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 356.0
SHD3_k127_2403233_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000002 228.0
SHD3_k127_2403233_3 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000002833 176.0
SHD3_k127_2410462_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 533.0
SHD3_k127_2410462_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 399.0
SHD3_k127_2410462_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000001458 174.0
SHD3_k127_2410462_3 enzyme related to lactoylglutathione lyase K06996 - - 0.000000000000000000000000000000000000000143 160.0
SHD3_k127_2410462_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 0.0000000000000000000000000000000001488 134.0
SHD3_k127_2410462_5 Cytochrome c - - - 0.00000000000000000000000000000003111 134.0
SHD3_k127_2410462_6 Glucose / Sorbosone dehydrogenase - - - 0.00000006263 64.0
SHD3_k127_2419237_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 297.0
SHD3_k127_2419237_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0001485 45.0
SHD3_k127_242024_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 4.082e-230 730.0
SHD3_k127_242024_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 444.0
SHD3_k127_242024_2 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
SHD3_k127_242024_3 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000166 188.0
SHD3_k127_242024_4 phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000002069 181.0
SHD3_k127_242024_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00220,K00800 - 1.3.1.12,1.3.1.43,2.5.1.19 0.0000000000000000000000000000000003079 143.0
SHD3_k127_242024_6 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K01835 - 5.4.2.2 0.0000000000000000003916 87.0
SHD3_k127_242024_7 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000003607 75.0
SHD3_k127_242024_8 FeoA K04758 - - 0.00000000004738 68.0
SHD3_k127_2424594_0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 535.0
SHD3_k127_2424594_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 351.0
SHD3_k127_2424594_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 287.0
SHD3_k127_2429968_0 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 2.285e-300 928.0
SHD3_k127_2429968_1 Carboxyl transferase domain - - - 8.863e-270 842.0
SHD3_k127_2429968_2 Acyclic terpene utilisation family protein AtuA - - - 5.406e-245 763.0
SHD3_k127_2429968_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 387.0
SHD3_k127_2429968_4 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000002716 229.0
SHD3_k127_2429968_5 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000004326 235.0
SHD3_k127_2429968_6 - - - - 0.00000000000000000000000000000000000000000000000000002167 193.0
SHD3_k127_2431785_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 560.0
SHD3_k127_2431785_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 377.0
SHD3_k127_2431785_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 340.0
SHD3_k127_2431785_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 315.0
SHD3_k127_2431785_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 307.0
SHD3_k127_2431785_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000001686 206.0
SHD3_k127_2431785_6 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000001801 123.0
SHD3_k127_2431785_7 Thiamine monophosphate synthase K00788,K10810 - 2.5.1.3,5.3.99.10 0.000000000000000000000000000009731 128.0
SHD3_k127_2431785_8 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000149 110.0
SHD3_k127_2431785_9 Bifunctional sulfur carrier protein thiazole synthase K03154 - - 0.0000000000001123 74.0
SHD3_k127_2432936_0 Zinc carboxypeptidase K14054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 553.0
SHD3_k127_2436641_0 Wzt C-terminal domain K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 369.0
SHD3_k127_2436641_1 Polysaccharide biosynthesis protein K15894 - 4.2.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 315.0
SHD3_k127_2436641_2 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000183 209.0
SHD3_k127_2439620_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.642e-280 869.0
SHD3_k127_2439620_1 Phosphate acetyl/butaryl transferase K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 6.372e-205 644.0
SHD3_k127_2439620_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 571.0
SHD3_k127_2439620_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 369.0
SHD3_k127_2439620_4 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000002058 129.0
SHD3_k127_244362_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 416.0
SHD3_k127_244362_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000002279 257.0
SHD3_k127_244362_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000001207 239.0
SHD3_k127_244362_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000006529 94.0
SHD3_k127_2444797_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000001249 191.0
SHD3_k127_2444797_1 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000008477 180.0
SHD3_k127_2444797_2 ABC-type transport system involved in cytochrome c biogenesis permease component K02194 - - 0.0000000000000000000000000000000000009013 147.0
SHD3_k127_2468053_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007528 243.0
SHD3_k127_2468053_1 Belongs to the CDS family - - - 0.000000000000000000000000000000000000000000000000000006336 194.0
SHD3_k127_2468053_2 translation release factor activity - - - 0.000003604 59.0
SHD3_k127_247736_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 9.977e-286 882.0
SHD3_k127_247736_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.703e-208 654.0
SHD3_k127_247736_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 563.0
SHD3_k127_247736_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 451.0
SHD3_k127_247736_4 YjbR - - - 0.000000000000000000000000000000000000000000000002649 176.0
SHD3_k127_2480864_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 314.0
SHD3_k127_2480864_1 protein methyltransferase activity K02687 - - 0.000000000000000000000000003025 123.0
SHD3_k127_2497363_0 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 312.0
SHD3_k127_2497363_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000045 258.0
SHD3_k127_2497363_2 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000003262 200.0
SHD3_k127_2497363_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000001861 189.0
SHD3_k127_2501772_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 530.0
SHD3_k127_2501772_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 430.0
SHD3_k127_2501772_2 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000932 237.0
SHD3_k127_2501772_3 SprT-like family - - - 0.00000000000000000000000000000000000000000000000000000000004689 213.0
SHD3_k127_2507180_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.933e-319 989.0
SHD3_k127_2507180_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 396.0
SHD3_k127_2554878_0 PFAM amine oxidase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 609.0
SHD3_k127_2554878_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 496.0
SHD3_k127_2554878_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 301.0
SHD3_k127_2554878_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004379 278.0
SHD3_k127_2554878_4 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001604 253.0
SHD3_k127_2557407_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 421.0
SHD3_k127_2557407_1 transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000004627 210.0
SHD3_k127_2557687_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 487.0
SHD3_k127_2570045_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 446.0
SHD3_k127_2570045_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 364.0
SHD3_k127_2570045_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000118 151.0
SHD3_k127_2570045_3 Predicted periplasmic lipoprotein (DUF2279) - - - 0.000000000000000000000000000008294 131.0
SHD3_k127_2590555_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 553.0
SHD3_k127_2590555_1 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000003084 140.0
SHD3_k127_2590555_2 - - - - 0.0002033 46.0
SHD3_k127_2606568_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001156 279.0
SHD3_k127_2606568_1 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003987 274.0
SHD3_k127_2606568_2 Cytochrome c K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006545 262.0
SHD3_k127_2606568_3 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000005057 199.0
SHD3_k127_2606568_4 CYTH domain K01768,K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000000000005483 181.0
SHD3_k127_2606568_5 - - - - 0.000000000000000000000000000000000000001418 151.0
SHD3_k127_2640962_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006661 233.0
SHD3_k127_2640962_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000002761 148.0
SHD3_k127_264697_0 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000004808 165.0
SHD3_k127_264697_1 PFAM Mechanosensitive ion channel - - - 0.00000000000000000000001069 104.0
SHD3_k127_2654822_0 TonB dependent receptor - - - 2.112e-306 953.0
SHD3_k127_2654822_1 epimerase K00329,K00356,K00491,K21572 - 1.14.14.47,1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000005511 191.0
SHD3_k127_2669089_0 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 524.0
SHD3_k127_2669089_1 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 429.0
SHD3_k127_2669089_2 protein histidine kinase activity K03407,K12257 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 284.0
SHD3_k127_2669089_3 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000002255 209.0
SHD3_k127_2680528_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 481.0
SHD3_k127_2680528_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 312.0
SHD3_k127_2680528_2 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000001983 155.0
SHD3_k127_2680528_3 Iron permease FTR1 K07243 - - 0.0000000000000000000000000004656 118.0
SHD3_k127_2680528_4 - - - - 0.000000000001598 75.0
SHD3_k127_2688787_0 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 518.0
SHD3_k127_2688787_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 458.0
SHD3_k127_2688787_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 400.0
SHD3_k127_2688787_3 DNA polymerase alpha chain like domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 362.0
SHD3_k127_2688787_4 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 330.0
SHD3_k127_2688787_5 - - - - 0.0000000000000000000000000000002911 128.0
SHD3_k127_2688787_6 SMART PDZ DHR GLGF domain protein - - - 0.0000000000000000000000003062 115.0
SHD3_k127_270827_0 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 385.0
SHD3_k127_2711956_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 443.0
SHD3_k127_2723431_0 ABC1 family - - - 4.896e-216 684.0
SHD3_k127_2723431_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000008509 221.0
SHD3_k127_2723431_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000001398 206.0
SHD3_k127_2723431_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000002258 149.0
SHD3_k127_2723431_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000008151 95.0
SHD3_k127_27331_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003057 244.0
SHD3_k127_27331_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000002151 158.0
SHD3_k127_2735732_0 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 322.0
SHD3_k127_2735732_1 KR domain - - - 0.00000000000000000000000000000000000000000000000543 176.0
SHD3_k127_2735732_2 - - - - 0.00000000000000000000000002839 118.0
SHD3_k127_277176_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 9.811e-269 849.0
SHD3_k127_277176_1 Aminotransferase - - - 0.0000000000000000001443 93.0
SHD3_k127_2772798_0 Sortilin, neurotensin receptor 3, - - - 2.652e-199 638.0
SHD3_k127_2772798_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000002598 248.0
SHD3_k127_277710_0 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 492.0
SHD3_k127_277710_1 CcmB protein K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 308.0
SHD3_k127_277710_2 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 304.0
SHD3_k127_277710_3 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000002556 184.0
SHD3_k127_277710_4 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000136 81.0
SHD3_k127_277928_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 501.0
SHD3_k127_277928_1 Pfam:SusD K21572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 470.0
SHD3_k127_277928_2 Outer membrane protein beta-barrel family - - - 0.000000000000000000000000000000003359 130.0
SHD3_k127_2785564_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 441.0
SHD3_k127_2785564_1 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000000006065 222.0
SHD3_k127_2785564_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000002404 171.0
SHD3_k127_2785564_3 - - - - 0.000000000000000000000000000000000000000005415 162.0
SHD3_k127_2787373_0 Catalase K03781 - 1.11.1.6 8.255e-241 756.0
SHD3_k127_2787373_1 SIS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 385.0
SHD3_k127_2787373_2 Protein conserved in bacteria K01446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 375.0
SHD3_k127_2787373_3 Beta-lactamase - - - 0.000000000000000000001839 101.0
SHD3_k127_2787373_4 Major Facilitator Superfamily - - - 0.00000001513 61.0
SHD3_k127_2796335_0 Belongs to the carbamoyltransferase HypF family K04656 - - 9.739e-205 662.0
SHD3_k127_2796335_1 PFAM cobalamin synthesis protein P47K K04652 - - 0.000000000000000000000000000000000000000000000000000000000000001107 226.0
SHD3_k127_2796335_2 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.00000000000000000000000000002156 128.0
SHD3_k127_2796335_3 Domain of unknown function (DUF4405) K03620 - - 0.000000000000000000000004167 108.0
SHD3_k127_2796335_4 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000002526 82.0
SHD3_k127_2798791_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000064 268.0
SHD3_k127_2798791_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000004949 262.0
SHD3_k127_2798791_2 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000005886 202.0
SHD3_k127_2798791_3 HIT domain K02503 - - 0.000000000000000000000000000000000000001707 151.0
SHD3_k127_2798791_4 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000001176 120.0
SHD3_k127_2798791_5 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001069 109.0
SHD3_k127_283217_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 321.0
SHD3_k127_283217_1 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000008481 212.0
SHD3_k127_2840140_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000844 279.0
SHD3_k127_2840140_1 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000008251 259.0
SHD3_k127_2840140_2 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000004396 140.0
SHD3_k127_2840140_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000001364 109.0
SHD3_k127_2840140_4 Putative ATP-binding cassette K01992 - - 0.000000000000203 76.0
SHD3_k127_2840406_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 6.437e-213 670.0
SHD3_k127_2840406_1 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 505.0
SHD3_k127_2840406_2 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 430.0
SHD3_k127_2840406_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 415.0
SHD3_k127_2840406_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 368.0
SHD3_k127_2840406_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001585 282.0
SHD3_k127_2840406_6 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000009142 232.0
SHD3_k127_2840406_7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000002233 213.0
SHD3_k127_2840406_8 GAF domain - - - 0.00000000000000000000000000000000000000000000000001166 192.0
SHD3_k127_2840406_9 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08313,K08314 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023 2.2.1.2 0.0000000000000000000000000000000000000000001131 167.0
SHD3_k127_2847766_0 Surface antigen K07277,K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 548.0
SHD3_k127_2847766_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 429.0
SHD3_k127_2847766_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000008109 182.0
SHD3_k127_2861816_0 CarboxypepD_reg-like domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 557.0
SHD3_k127_2861816_1 COGs COG4299 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 460.0
SHD3_k127_2862797_0 COGs COG2380 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006042 277.0
SHD3_k127_2862797_1 DbpA RNA binding domain K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000008973 251.0
SHD3_k127_2862797_2 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000003493 137.0
SHD3_k127_2862797_3 COG0433 Predicted ATPase K06915 - - 0.0000001251 53.0
SHD3_k127_2867244_0 Sodium:solute symporter family K14392 - - 1.384e-196 620.0
SHD3_k127_2867244_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 511.0
SHD3_k127_2867244_2 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 383.0
SHD3_k127_2867244_3 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000007116 240.0
SHD3_k127_2867244_4 - - - - 0.000000000000000000000000000000001079 137.0
SHD3_k127_2868607_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 392.0
SHD3_k127_2868607_1 dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000006001 203.0
SHD3_k127_2868607_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000006336 194.0
SHD3_k127_2868607_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000009655 185.0
SHD3_k127_2868607_4 - - - - 0.000000000000000000000000000003656 120.0
SHD3_k127_2868607_5 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000009969 124.0
SHD3_k127_286968_0 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 442.0
SHD3_k127_286968_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000001026 216.0
SHD3_k127_2879917_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 404.0
SHD3_k127_2879917_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 362.0
SHD3_k127_2879917_2 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 355.0
SHD3_k127_2891829_0 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005889 264.0
SHD3_k127_2891829_1 hemerythrin HHE cation binding domain - - - 0.000000000000006163 78.0
SHD3_k127_2892061_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.227e-222 698.0
SHD3_k127_2892061_1 Domain of unknown function (DUF2383) - - - 0.0000000000000000000000000000000007026 136.0
SHD3_k127_2892061_2 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000001792 70.0
SHD3_k127_2899404_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 519.0
SHD3_k127_2899404_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 404.0
SHD3_k127_2899404_10 - - - - 0.000000000000003585 81.0
SHD3_k127_2899404_11 - - - - 0.000000000002234 74.0
SHD3_k127_2899404_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 357.0
SHD3_k127_2899404_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000008057 267.0
SHD3_k127_2899404_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000102 239.0
SHD3_k127_2899404_5 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000003181 217.0
SHD3_k127_2899404_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000003182 207.0
SHD3_k127_2899404_7 - - - - 0.000000000000000000000000000000000000000000000001571 190.0
SHD3_k127_2899404_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000003689 160.0
SHD3_k127_2899404_9 Ribosomal protein S16 K02959 - - 0.00000000000000000000000000000000002697 138.0
SHD3_k127_2903138_0 ABC transporter transmembrane region K11085 - - 5.403e-233 737.0
SHD3_k127_2903138_1 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 421.0
SHD3_k127_2903138_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000005958 195.0
SHD3_k127_2903138_3 LemA family K03744 - - 0.0001385 46.0
SHD3_k127_2923610_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 587.0
SHD3_k127_2923610_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 356.0
SHD3_k127_2923610_2 cyclic nucleotide binding K12132,K20074 - 2.7.11.1,3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 353.0
SHD3_k127_2923610_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 314.0
SHD3_k127_2923610_4 Pirin C-terminal cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 293.0
SHD3_k127_2923610_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001955 263.0
SHD3_k127_2923610_6 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000000000000000001036 199.0
SHD3_k127_2923610_7 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000009188 150.0
SHD3_k127_2923610_8 Cupin 2, conserved barrel domain protein - - - 0.0000002755 59.0
SHD3_k127_2923610_9 PFAM Methylamine utilisation protein MauE - - - 0.000004993 55.0
SHD3_k127_2928221_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 591.0
SHD3_k127_2928221_1 sirohydrochlorin cobaltochelatase activity K03794 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.4 0.0000000000000000000000005046 109.0
SHD3_k127_2928221_2 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000003406 78.0
SHD3_k127_2929719_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 474.0
SHD3_k127_2929719_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 299.0
SHD3_k127_2929719_2 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007694 280.0
SHD3_k127_2929719_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000007272 124.0
SHD3_k127_2931376_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.559e-223 703.0
SHD3_k127_2931376_1 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002151 277.0
SHD3_k127_294267_0 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
SHD3_k127_294267_1 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004857 274.0
SHD3_k127_294267_2 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000000000000634 161.0
SHD3_k127_294267_3 Glycosyl transferases group 1 - - - 0.00000000000006944 83.0
SHD3_k127_2951746_0 Phosphoribosylglycinamide synthetase, C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 541.0
SHD3_k127_2951746_1 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000002643 233.0
SHD3_k127_2951746_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001001 237.0
SHD3_k127_2951746_3 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000001148 183.0
SHD3_k127_2951746_4 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000005079 150.0
SHD3_k127_2951746_5 - - - - 0.0000000000000000000001198 101.0
SHD3_k127_2951746_6 Anti-sigma-K factor rskA - - - 0.00000000004227 74.0
SHD3_k127_2951746_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000004072 68.0
SHD3_k127_295919_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 549.0
SHD3_k127_295919_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 397.0
SHD3_k127_295919_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 365.0
SHD3_k127_295919_3 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000412 266.0
SHD3_k127_295919_4 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000002837 190.0
SHD3_k127_296439_0 - - - - 0.000000000000000000000002794 117.0
SHD3_k127_2971677_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 578.0
SHD3_k127_2975638_0 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 393.0
SHD3_k127_2975638_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000004436 256.0
SHD3_k127_2977273_0 AcrB/AcrD/AcrF family K03296 - - 2.279e-213 673.0
SHD3_k127_297858_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 2.504e-311 970.0
SHD3_k127_297858_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 529.0
SHD3_k127_297858_2 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 458.0
SHD3_k127_297858_3 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 384.0
SHD3_k127_297858_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 383.0
SHD3_k127_297858_5 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 327.0
SHD3_k127_2998038_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 590.0
SHD3_k127_2998038_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 578.0
SHD3_k127_2998038_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 542.0
SHD3_k127_2998038_3 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000003346 175.0
SHD3_k127_2998038_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000006304 89.0
SHD3_k127_2998050_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 3.266e-283 910.0
SHD3_k127_2998050_1 Domain of unknown function (DUF4173) - - - 0.0000000000000000000000000000000000003252 158.0
SHD3_k127_2998050_2 Peptidase dimerisation domain - - - 0.00000000000004821 72.0
SHD3_k127_3001049_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 450.0
SHD3_k127_3001049_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K00950,K01633 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000000000000000000000000003616 253.0
SHD3_k127_3001049_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000188 224.0
SHD3_k127_3005326_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 523.0
SHD3_k127_3005326_1 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 311.0
SHD3_k127_3005326_2 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000001209 225.0
SHD3_k127_3005326_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000001111 188.0
SHD3_k127_3008090_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 368.0
SHD3_k127_3008090_1 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000716 241.0
SHD3_k127_3008090_2 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000000000000000000000003454 239.0
SHD3_k127_3008090_3 DinB family - - - 0.0000000000000000000000000000000005856 136.0
SHD3_k127_300957_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 429.0
SHD3_k127_300957_1 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008007 276.0
SHD3_k127_3016039_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 480.0
SHD3_k127_3016039_1 secondary active sulfate transmembrane transporter activity K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 441.0
SHD3_k127_3016039_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 415.0
SHD3_k127_3016039_3 Disulphide isomerase - - - 0.00000000000000000000000000000000000000000000000000000003653 203.0
SHD3_k127_3016039_4 - - - - 0.0000000000000000000000000001397 122.0
SHD3_k127_3017205_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 482.0
SHD3_k127_3017205_1 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 466.0
SHD3_k127_3017205_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 428.0
SHD3_k127_3017205_3 dihydrofolate reductase activity K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000001734 229.0
SHD3_k127_3017205_4 DinB family - - - 0.00000000000000000000000000000000000000000006464 166.0
SHD3_k127_3017205_5 DinB superfamily - - - 0.00000000000000000000000000000000000001236 150.0
SHD3_k127_3017205_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000004119 148.0
SHD3_k127_3017205_7 DinB superfamily K07552 - - 0.0000000000000000000000000000002849 130.0
SHD3_k127_3017205_8 transferase activity, transferring acyl groups K03824,K15520 - 2.3.1.189 0.000000000000000000000000001908 118.0
SHD3_k127_3017531_0 DinB superfamily K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 462.0
SHD3_k127_3017531_1 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000004787 266.0
SHD3_k127_3017531_2 Glutamate-cysteine ligase family 2(GCS2) K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000002475 192.0
SHD3_k127_3017531_4 ABC transporter K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.00000000000000000000000001533 113.0
SHD3_k127_3020938_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1144.0
SHD3_k127_3020938_1 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 1.367e-270 850.0
SHD3_k127_3020938_2 NAD synthase K01916 - 6.3.1.5 4.604e-251 790.0
SHD3_k127_3020938_3 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000007997 188.0
SHD3_k127_3020938_4 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000003127 183.0
SHD3_k127_3020938_5 Yip1 domain - - - 0.000000000000000000000000000000000000000000000002878 178.0
SHD3_k127_302301_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 3.346e-305 956.0
SHD3_k127_302301_1 Putative modulator of DNA gyrase K03568 - - 8.944e-249 777.0
SHD3_k127_302301_10 - - - - 0.00006319 49.0
SHD3_k127_302301_12 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000737 48.0
SHD3_k127_302301_2 Putative modulator of DNA gyrase - - - 1.065e-195 622.0
SHD3_k127_302301_3 nucleotide catabolic process K01081,K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 466.0
SHD3_k127_302301_4 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003839 283.0
SHD3_k127_302301_5 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.0000000000000000000000000000000000000003521 156.0
SHD3_k127_302301_6 Transcriptional regulator K07729 - - 0.000000000000001426 78.0
SHD3_k127_302301_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000002275 64.0
SHD3_k127_3031496_0 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 599.0
SHD3_k127_3031496_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 340.0
SHD3_k127_3031496_2 - - - - 0.0000000000000000000000000000000000000000000000001264 187.0
SHD3_k127_3040917_0 Acts as a magnesium transporter K06213 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 529.0
SHD3_k127_3040917_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 427.0
SHD3_k127_3040917_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 353.0
SHD3_k127_3040917_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000000008651 218.0
SHD3_k127_3040917_4 Ham1 family K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000002159 213.0
SHD3_k127_3040917_5 Lipopolysaccharide-assembly - - - 0.00000000000000000000000000000000000000000000000000002468 195.0
SHD3_k127_3040917_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000006138 179.0
SHD3_k127_3040917_7 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000006335 138.0
SHD3_k127_3047426_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 360.0
SHD3_k127_3047426_1 Stage II sporulation protein E (SpoIIE) - - - 0.000000000000000000000000000000000001578 158.0
SHD3_k127_3047426_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000006569 55.0
SHD3_k127_3050493_0 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008897 285.0
SHD3_k127_3050493_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000003733 213.0
SHD3_k127_3059543_0 PFAM Protein kinase domain - - - 3.589e-214 701.0
SHD3_k127_3059543_1 response to antibiotic K00573 - 2.1.1.77 9.467e-194 614.0
SHD3_k127_3059543_10 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K03921 - 1.14.19.11,1.14.19.2,1.14.19.26,1.16.3.1 0.0000178 55.0
SHD3_k127_3059543_2 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002718 269.0
SHD3_k127_3059543_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000002188 237.0
SHD3_k127_3059543_4 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000009204 191.0
SHD3_k127_3059543_5 Acetyltransferase (GNAT) domain K02348 - - 0.0000000000000000000000000000000000000000000003546 171.0
SHD3_k127_3059543_6 glyoxalase III activity - - - 0.0000000000000000000000000000000000000001039 157.0
SHD3_k127_3059543_7 Fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000001434 139.0
SHD3_k127_3059543_8 DinB superfamily - - - 0.000000000001429 75.0
SHD3_k127_3059543_9 Protein of unknown function (DUF455) - - - 0.000004141 57.0
SHD3_k127_3081013_0 TonB dependent receptor - - - 8.305e-274 875.0
SHD3_k127_3081013_1 AMP-binding enzyme C-terminal domain K01907 - 6.2.1.16 4.879e-272 853.0
SHD3_k127_3081013_2 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 1.409e-224 699.0
SHD3_k127_3081013_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 493.0
SHD3_k127_3081013_4 SusD family K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 343.0
SHD3_k127_3081013_5 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003597 252.0
SHD3_k127_3081013_6 Peptidase family M20/M25/M40 - - - 0.000000000000000000000000000000000000000000000000000000001621 207.0
SHD3_k127_3081013_7 - - - - 0.0000000008236 63.0
SHD3_k127_3081013_8 - - - - 0.000000963 57.0
SHD3_k127_3090933_0 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 318.0
SHD3_k127_3090933_1 Transporter, major facilitator family protein - - - 0.0000000000000000000000000000000000000000000000000000000000176 218.0
SHD3_k127_3090933_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000003884 143.0
SHD3_k127_3090933_3 DinB superfamily - - - 0.00000000000000000000000000000000002387 142.0
SHD3_k127_3095315_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 437.0
SHD3_k127_3095315_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 396.0
SHD3_k127_3095315_2 proteins of the AP superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000009235 247.0
SHD3_k127_3095315_3 - - - - 0.0000000000000000000000000000000000000000001934 167.0
SHD3_k127_3095315_4 - - - - 0.0000000000000007306 80.0
SHD3_k127_3104546_0 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 557.0
SHD3_k127_3104546_1 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 308.0
SHD3_k127_3112729_0 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 321.0
SHD3_k127_3112729_1 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000001022 161.0
SHD3_k127_3112729_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000004709 169.0
SHD3_k127_3113507_0 Amidohydrolase family K06015 - 3.5.1.81 2.305e-244 766.0
SHD3_k127_3113507_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 498.0
SHD3_k127_3113507_2 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 323.0
SHD3_k127_3113507_3 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007874 255.0
SHD3_k127_3113507_4 PFAM Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000129 153.0
SHD3_k127_3113507_6 SnoaL-like polyketide cyclase - - - 0.000000001341 66.0
SHD3_k127_3119251_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.0 1541.0
SHD3_k127_312072_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 542.0
SHD3_k127_312072_1 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 369.0
SHD3_k127_312072_2 YtxH-like protein - - - 0.0000000000000000000000004479 107.0
SHD3_k127_3139052_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 595.0
SHD3_k127_3139052_1 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 462.0
SHD3_k127_3139052_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 428.0
SHD3_k127_3139052_3 Transcription elongation factor, N-terminal K03624 - - 0.00000000000000000000000000000000000000000000000000000000000001004 222.0
SHD3_k127_3139052_4 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000005276 114.0
SHD3_k127_3139052_5 - - - - 0.00000000028 65.0
SHD3_k127_3151725_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1032.0
SHD3_k127_3151725_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 332.0
SHD3_k127_3151725_2 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001303 241.0
SHD3_k127_3151725_3 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000011 241.0
SHD3_k127_3151725_4 - - - - 0.00000000000000000000000000000000000000000000000345 175.0
SHD3_k127_3151725_5 VKc - - - 0.0000000000000000000497 96.0
SHD3_k127_3151725_6 - - - - 0.000000000001212 68.0
SHD3_k127_3155619_0 Sodium:dicarboxylate symporter family K11103 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 580.0
SHD3_k127_3155619_1 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 426.0
SHD3_k127_3155619_2 protein kinase activity - - - 0.0000000000000000000000000000001784 127.0
SHD3_k127_3160274_0 Sugar nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 452.0
SHD3_k127_3160274_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002466 265.0
SHD3_k127_3160274_2 Glycosyltransferase like family 2 - - - 0.000005367 48.0
SHD3_k127_3160398_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1036.0
SHD3_k127_3170613_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 411.0
SHD3_k127_3170613_1 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000916 267.0
SHD3_k127_3170613_2 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000005154 190.0
SHD3_k127_3189501_0 Type ii secretion system protein e K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 346.0
SHD3_k127_3189501_1 Type ii secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001375 261.0
SHD3_k127_3189501_2 type II secretion system K12511 - - 0.00000000000000000000000000000000000000001767 164.0
SHD3_k127_3189501_3 TadE-like protein - - - 0.0000008651 59.0
SHD3_k127_319364_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 298.0
SHD3_k127_319364_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000001214 170.0
SHD3_k127_319364_2 Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000001243 169.0
SHD3_k127_3201530_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.845e-245 766.0
SHD3_k127_3201530_1 - - - - 0.00000000000000000000000000000000000000003363 160.0
SHD3_k127_3201530_2 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000003255 136.0
SHD3_k127_3201530_3 ketosteroid isomerase - - - 0.0000000000000000000000000001086 127.0
SHD3_k127_3201530_4 WHG domain - - - 0.00000000000000000001218 99.0
SHD3_k127_3201990_0 COG0433 Predicted ATPase K06915 - - 7.331e-221 692.0
SHD3_k127_3212776_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 537.0
SHD3_k127_3212776_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 454.0
SHD3_k127_3212776_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 314.0
SHD3_k127_3212776_3 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 297.0
SHD3_k127_3212776_4 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000001017 185.0
SHD3_k127_3218773_0 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000024 269.0
SHD3_k127_3218773_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000007957 236.0
SHD3_k127_3218773_2 Methyltransferase - - - 0.00000005049 54.0
SHD3_k127_3232015_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 565.0
SHD3_k127_3238737_0 tRNA synthetases class I (M) K01874 - 6.1.1.10 6.495e-233 729.0
SHD3_k127_3238737_1 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 441.0
SHD3_k127_3243464_0 PFAM Amidase - - - 6.699e-198 634.0
SHD3_k127_3243464_1 Isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 561.0
SHD3_k127_3243464_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 525.0
SHD3_k127_3243464_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 511.0
SHD3_k127_3243464_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 363.0
SHD3_k127_3243464_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000001388 185.0
SHD3_k127_3243464_6 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000001604 149.0
SHD3_k127_3243464_7 - - - - 0.0000000000000003164 82.0
SHD3_k127_3243464_8 Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat - - - 0.0000001048 64.0
SHD3_k127_3243464_9 alginic acid biosynthetic process K10297 - - 0.0008175 45.0
SHD3_k127_324348_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1078.0
SHD3_k127_324348_1 Domain of unknown function (DUF4384) - - - 0.00000179 59.0
SHD3_k127_3250602_0 SPFH Band 7 PHB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 327.0
SHD3_k127_3250602_1 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000002344 261.0
SHD3_k127_3250602_2 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.000000000000000000000008015 106.0
SHD3_k127_3255145_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 546.0
SHD3_k127_3255145_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 380.0
SHD3_k127_3255145_2 PFAM metal-dependent phosphohydrolase, HD sub domain K02030,K06950,K07814,K09749,K16923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000313 272.0
SHD3_k127_3255145_3 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001511 277.0
SHD3_k127_3255145_4 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007732 243.0
SHD3_k127_3255145_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000001188 186.0
SHD3_k127_3255145_6 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000003427 164.0
SHD3_k127_3255145_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000004826 151.0
SHD3_k127_3255145_8 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000009543 84.0
SHD3_k127_3255145_9 - - - - 0.00001655 49.0
SHD3_k127_3255894_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 424.0
SHD3_k127_3255894_1 tRNA methylthiotransferase YqeV K18707 - 2.8.4.5 0.0000000000000000000000000000000001662 145.0
SHD3_k127_326474_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 5.973e-220 691.0
SHD3_k127_326474_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 610.0
SHD3_k127_326474_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 496.0
SHD3_k127_326474_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 306.0
SHD3_k127_326474_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000001486 209.0
SHD3_k127_326474_5 Telomere recombination K07566 - 2.7.7.87 0.00000000000002886 80.0
SHD3_k127_3265127_0 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 325.0
SHD3_k127_3265127_1 alpha beta K06889 - - 0.000000000000000000000000000000000000001892 155.0
SHD3_k127_3265127_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000002702 137.0
SHD3_k127_3271720_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1182.0
SHD3_k127_3271720_1 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 418.0
SHD3_k127_3271720_2 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000137 120.0
SHD3_k127_3279753_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 6.645e-197 622.0
SHD3_k127_3279753_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 339.0
SHD3_k127_3279753_2 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 308.0
SHD3_k127_3279753_3 PTS system sorbose-specific iic component K02795 - - 0.000000000000000000000000000000000000000000000000000000000002799 216.0
SHD3_k127_3279753_4 PTS system sorbose subfamily IIB component K19507 - - 0.000000000000000000000000000000000000000000000000000000000009735 211.0
SHD3_k127_3279753_5 PTS system fructose IIA component K02744 - - 0.0000000000000000000000000001013 121.0
SHD3_k127_3279753_6 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000000001619 118.0
SHD3_k127_3285520_0 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 460.0
SHD3_k127_3285520_1 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 370.0
SHD3_k127_3285520_2 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 344.0
SHD3_k127_3285520_3 - - - - 0.000000000000000000000000001378 114.0
SHD3_k127_3285520_4 metalloendopeptidase activity K08602 - - 0.0000000000000007761 78.0
SHD3_k127_3287840_0 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 353.0
SHD3_k127_3287840_1 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0000000000000000000000000000000000000000000000003633 178.0
SHD3_k127_3291663_0 beta-galactosidase activity K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165 0.0 1347.0
SHD3_k127_3291663_1 Amino acid permease K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 1.082e-233 727.0
SHD3_k127_3291663_11 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity K13991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 - 0.000000000000000001175 96.0
SHD3_k127_3291663_12 Protein of unknown function (DUF4230) - - - 0.0000001055 62.0
SHD3_k127_3291663_2 lysine biosynthetic process via aminoadipic acid - - - 7.606e-205 670.0
SHD3_k127_3291663_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 531.0
SHD3_k127_3291663_4 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 351.0
SHD3_k127_3291663_5 Belongs to the MenA family. Type 1 subfamily K02548 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000005181 239.0
SHD3_k127_3291663_6 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000002506 205.0
SHD3_k127_3291663_7 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000005116 199.0
SHD3_k127_3291663_8 DinB family - - - 0.000000000000000000000000000000000000000000000001409 179.0
SHD3_k127_3291663_9 beta-lactamase - - - 0.000000000000000000000000000103 116.0
SHD3_k127_3299200_0 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 0.0 1021.0
SHD3_k127_3299200_1 Thiolase, C-terminal domain K02615 - 2.3.1.174,2.3.1.223 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 544.0
SHD3_k127_3299200_2 Bacterial transferase hexapeptide (six repeats) K02617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 313.0
SHD3_k127_3299200_3 lactoylglutathione lyase activity K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001586 259.0
SHD3_k127_3299200_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001066 237.0
SHD3_k127_3299200_5 - - - - 0.000000000000000000000000000000000004098 141.0
SHD3_k127_3299200_6 - - - - 0.0000000000000000000000000000001107 139.0
SHD3_k127_3299200_7 COG0657 Esterase lipase - - - 0.000000000002035 70.0
SHD3_k127_3299200_8 - - - - 0.00001056 58.0
SHD3_k127_3307261_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 581.0
SHD3_k127_3307261_1 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 517.0
SHD3_k127_3307261_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 384.0
SHD3_k127_3307261_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 373.0
SHD3_k127_3307261_4 Beta-eliminating lyase K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 302.0
SHD3_k127_3307261_5 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000001956 220.0
SHD3_k127_3307261_6 - - - - 0.00000000000000000000000000000000000000000000000000004925 198.0
SHD3_k127_3307261_7 HNH nucleases - - - 0.00000000000000000000000000000000000005938 144.0
SHD3_k127_3323825_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 415.0
SHD3_k127_3355_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 455.0
SHD3_k127_3355_1 PAS domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006893 264.0
SHD3_k127_3355_2 Transmembrane and - - - 0.00000000000000000000000000000006845 144.0
SHD3_k127_3355_3 Transmembrane and TPR repeat-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827 - 0.00000000000000000000000000004501 134.0
SHD3_k127_3355_4 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.000000000000000004563 88.0
SHD3_k127_3369934_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001713 277.0
SHD3_k127_3369934_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002077 234.0
SHD3_k127_3369934_2 SnoaL-like domain - - - 0.000000000000000000000000000000000000001655 153.0
SHD3_k127_3369934_3 - - - - 0.000003549 49.0
SHD3_k127_3374597_0 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 293.0
SHD3_k127_3374597_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000002544 240.0
SHD3_k127_3374597_2 Domain of unknown function (DUF4388) - - - 0.0000000001906 64.0
SHD3_k127_3383301_0 Multicopper oxidase K08100 - 1.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 345.0
SHD3_k127_3383301_1 Cytochrome c K00376,K02305,K17760 - 1.1.9.1,1.7.2.4 0.0000000000000000000000000000000000000000000000000000000000001374 221.0
SHD3_k127_3383301_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000001673 207.0
SHD3_k127_3383301_3 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000006831 214.0
SHD3_k127_3383301_4 heme binding - - - 0.000000000000000000000000000000000000000000000000000000001496 211.0
SHD3_k127_3383301_5 - - - - 0.00000000000000000000000000000000000000000000000003195 188.0
SHD3_k127_3383301_6 DinB family - - - 0.00000000000000000000000000000000000000000000000123 177.0
SHD3_k127_3383301_7 - - - - 0.000000000000000000000000000000000001168 148.0
SHD3_k127_3383301_8 - - - - 0.0000000000000000000001472 107.0
SHD3_k127_3387902_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 524.0
SHD3_k127_3387902_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000006472 209.0
SHD3_k127_3387902_2 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000006513 140.0
SHD3_k127_3387902_3 - - - - 0.00000000000000000000000000005196 124.0
SHD3_k127_3387902_4 - - - - 0.000000000000000007622 91.0
SHD3_k127_3391372_0 Amino acid kinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 596.0
SHD3_k127_3402825_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006147 254.0
SHD3_k127_3402825_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000001713 220.0
SHD3_k127_340871_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 488.0
SHD3_k127_340871_1 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 447.0
SHD3_k127_340871_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 422.0
SHD3_k127_340871_3 domain, Protein - - - 0.0000000000000000000000000000007475 137.0
SHD3_k127_3423767_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 6.913e-289 898.0
SHD3_k127_3431784_0 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 510.0
SHD3_k127_3431784_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 467.0
SHD3_k127_3431784_10 - - - - 0.0000000000000000000000165 103.0
SHD3_k127_3431784_11 Domain of unknown function (DUF4412) - - - 0.00000000000000001215 94.0
SHD3_k127_3431784_2 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 454.0
SHD3_k127_3431784_3 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 427.0
SHD3_k127_3431784_4 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 374.0
SHD3_k127_3431784_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 371.0
SHD3_k127_3431784_6 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003171 291.0
SHD3_k127_3431784_7 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000004013 184.0
SHD3_k127_3431784_8 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000004646 158.0
SHD3_k127_3431784_9 - - - - 0.000000000000000000000000000007326 126.0
SHD3_k127_343434_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1128.0
SHD3_k127_343434_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.049e-233 727.0
SHD3_k127_343434_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 1.83e-227 713.0
SHD3_k127_343434_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 292.0
SHD3_k127_3439818_0 Involved in the tonB-independent uptake of proteins - - - 1.304e-243 774.0
SHD3_k127_3439818_1 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 402.0
SHD3_k127_3439818_2 Sporulation related domain - - - 0.0000000000000000000000008425 114.0
SHD3_k127_3471317_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.353e-260 809.0
SHD3_k127_3471317_1 TonB-dependent receptor - - - 2.153e-249 809.0
SHD3_k127_3471317_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 311.0
SHD3_k127_3471317_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 308.0
SHD3_k127_3471317_4 EAL domain K13950,K21025 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000009389 253.0
SHD3_k127_3471317_5 EAL domain - - - 0.00000000000000000000000000000000000000000000000000002216 207.0
SHD3_k127_3471317_6 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000191 170.0
SHD3_k127_3471317_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000001297 117.0
SHD3_k127_3471317_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000005782 101.0
SHD3_k127_3471317_9 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000003022 80.0
SHD3_k127_347709_1 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000009435 120.0
SHD3_k127_347709_2 TPR domain protein - - - 0.0003837 51.0
SHD3_k127_3487437_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 505.0
SHD3_k127_3487437_1 Predicted membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000008309 162.0
SHD3_k127_3487437_2 Dodecin K09165 - - 0.000000000000000000007456 93.0
SHD3_k127_3487437_3 cellulase activity - - - 0.000004306 55.0
SHD3_k127_3502651_0 Outer membrane protein beta-barrel family - - - 1.897e-296 939.0
SHD3_k127_3502651_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 9.418e-199 635.0
SHD3_k127_3502651_2 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000004853 128.0
SHD3_k127_3517280_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.428e-294 912.0
SHD3_k127_3517280_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 470.0
SHD3_k127_3517280_2 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 360.0
SHD3_k127_3517280_3 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 363.0
SHD3_k127_3517280_4 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 357.0
SHD3_k127_3517280_5 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000000000000000000000001646 138.0
SHD3_k127_3517280_6 - - - - 0.00000000000000000000000000000000006745 139.0
SHD3_k127_3517280_7 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000008663 64.0
SHD3_k127_3518204_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 344.0
SHD3_k127_3518204_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004463 276.0
SHD3_k127_3518204_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000003118 236.0
SHD3_k127_3518204_3 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000001055 218.0
SHD3_k127_3550574_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 576.0
SHD3_k127_3550574_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 386.0
SHD3_k127_3550574_2 Pfam Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 355.0
SHD3_k127_3550574_3 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 304.0
SHD3_k127_3550574_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002071 277.0
SHD3_k127_3550574_5 - - - - 0.000000000000000000000000000000000000000000000002221 194.0
SHD3_k127_3550574_6 - - - - 0.00000000000000000000000000000000000000008581 151.0
SHD3_k127_3550574_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000002594 81.0
SHD3_k127_3550738_0 Polysaccharide biosynthesis/export protein - - - 1.039e-210 673.0
SHD3_k127_3551173_0 Sortilin, neurotensin receptor 3, - - - 0.0 1223.0
SHD3_k127_3551173_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 545.0
SHD3_k127_3551173_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004046 222.0
SHD3_k127_3586764_0 Oxidoreductase family, NAD-binding Rossmann fold K00118,K13020 - 1.1.1.335,1.1.99.28 0.00000000000000000000000000000000000000000000000000000001507 214.0
SHD3_k127_3586764_1 Glycosyl transferase, family 2 - - - 0.000000000000003373 86.0
SHD3_k127_3586764_2 PFAM Glycosyl transferases group 1 - - - 0.0000000000002841 74.0
SHD3_k127_360639_0 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 593.0
SHD3_k127_360639_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 390.0
SHD3_k127_360639_2 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 369.0
SHD3_k127_360639_3 Domain of unknown function (DUF4186) - - - 0.000000000000000000000000000000000000000000000000006081 182.0
SHD3_k127_360639_4 - - - - 0.000000000000000000000000000000000000000000001242 172.0
SHD3_k127_360639_5 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000004377 125.0
SHD3_k127_3606529_0 Glutamine synthetase, catalytic domain K01915 GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 322.0
SHD3_k127_3606529_1 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 299.0
SHD3_k127_3606529_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000009188 150.0
SHD3_k127_3611353_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 568.0
SHD3_k127_3612796_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 528.0
SHD3_k127_3612796_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 324.0
SHD3_k127_3612796_2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.0000000000000001564 78.0
SHD3_k127_3618678_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 452.0
SHD3_k127_3618678_1 - - - - 0.000000000000000000000000000000000003382 145.0
SHD3_k127_3620160_0 MMPL family K03296 - - 0.0 1122.0
SHD3_k127_3620160_1 Uncharacterized protein family (UPF0051) K09014 - - 2.714e-258 801.0
SHD3_k127_3620160_2 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 460.0
SHD3_k127_3620160_3 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 403.0
SHD3_k127_3620160_4 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 306.0
SHD3_k127_3620160_5 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008169 291.0
SHD3_k127_3620160_6 SnoaL-like domain - - - 0.000000000000000000000000004636 112.0
SHD3_k127_3620160_7 - - - - 0.00000000000000002529 83.0
SHD3_k127_3620160_8 ATPase activity - - - 0.0000000001077 69.0
SHD3_k127_3622381_0 xanthine dehydrogenase activity - - - 0.0 1148.0
SHD3_k127_3622381_1 XdhC and CoxI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 453.0
SHD3_k127_3622381_10 - - - - 0.000000000000000000000000000000005902 136.0
SHD3_k127_3622381_11 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000001446 110.0
SHD3_k127_3622381_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 447.0
SHD3_k127_3622381_3 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 367.0
SHD3_k127_3622381_4 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 367.0
SHD3_k127_3622381_5 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 360.0
SHD3_k127_3622381_6 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 359.0
SHD3_k127_3622381_7 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001916 260.0
SHD3_k127_3622381_8 2 iron, 2 sulfur cluster binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000001371 241.0
SHD3_k127_3622381_9 MobA-Related Protein K00087,K07141,K07402,K19190 - 1.1.1.328,1.17.1.4,2.7.7.76 0.0000000000000000000000000000000000000000001488 166.0
SHD3_k127_3632183_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 602.0
SHD3_k127_3632183_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 592.0
SHD3_k127_3632183_2 - - - - 0.00000000000000000000000000000006841 128.0
SHD3_k127_3632183_3 Sodium:dicarboxylate symporter family K11103 - - 0.00000000000000033 82.0
SHD3_k127_3642119_0 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 5.088e-236 739.0
SHD3_k127_3642119_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 554.0
SHD3_k127_3645919_0 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 336.0
SHD3_k127_3645919_1 Belongs to the universal stress protein A family - - - 0.0000001667 63.0
SHD3_k127_3660401_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 1.596e-282 893.0
SHD3_k127_3660401_1 heat shock protein binding - - - 0.000000000000000000000000000009066 132.0
SHD3_k127_3660401_2 anaerobic respiration K02568 - - 0.00000000000000003298 91.0
SHD3_k127_3660401_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000005554 92.0
SHD3_k127_3667095_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 576.0
SHD3_k127_3667095_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002097 266.0
SHD3_k127_3683011_0 LysM domain K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 371.0
SHD3_k127_3683011_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000137 256.0
SHD3_k127_3683011_2 Belongs to the binding-protein-dependent transport system permease family K05832 - - 0.000000000000000000000000000000000000000000000000000000000000000001924 251.0
SHD3_k127_3683011_3 negative regulation of transcription, DNA-templated - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000002201 156.0
SHD3_k127_3683011_4 PFAM YceI-like domain - - - 0.0000000007148 69.0
SHD3_k127_368722_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.218e-195 616.0
SHD3_k127_368722_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000007458 231.0
SHD3_k127_368722_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000004208 170.0
SHD3_k127_3688158_0 membrane organization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 398.0
SHD3_k127_3692069_0 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 516.0
SHD3_k127_3692069_1 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 387.0
SHD3_k127_3692069_2 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 309.0
SHD3_k127_3692069_3 proteinase inhibitor I4 serpin K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 312.0
SHD3_k127_3692069_4 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 311.0
SHD3_k127_3692069_5 - - - - 0.0000000000000000000000000000000000000000000000000000001656 211.0
SHD3_k127_3692069_6 Bacterial transcription activator, effector binding domain - - - 0.0000000000000000000000001156 115.0
SHD3_k127_3692069_7 Psort location Periplasmic, score K09807 - - 0.000000000000001776 86.0
SHD3_k127_3695735_0 RecQ zinc-binding K03654 - 3.6.4.12 1.002e-241 761.0
SHD3_k127_3695735_1 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843,K02849,K12982 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 359.0
SHD3_k127_3695735_2 transferase activity, transferring glycosyl groups - - - 0.000000002957 67.0
SHD3_k127_3699716_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 503.0
SHD3_k127_3699716_1 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 493.0
SHD3_k127_3699716_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 432.0
SHD3_k127_3699716_3 Protein of unknown function (DUF1194) K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 424.0
SHD3_k127_3699716_4 - - - - 0.00000000000000000000000000000000000002296 156.0
SHD3_k127_3699716_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000001313 126.0
SHD3_k127_3699716_6 S4 RNA-binding domain K06178 - 5.4.99.22 0.000000000000004366 76.0
SHD3_k127_3700386_0 protein histidine kinase activity - - - 0.0 1019.0
SHD3_k127_3700386_1 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 343.0
SHD3_k127_3700386_2 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000007181 197.0
SHD3_k127_3700386_3 PLD-like domain - - - 0.0000003307 54.0
SHD3_k127_3700386_4 cheY-homologous receiver domain K20977 - - 0.000001994 54.0
SHD3_k127_3704805_0 - - - - 0.0000000000000000000000001922 119.0
SHD3_k127_3704805_1 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.00000000000000004439 86.0
SHD3_k127_3720042_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 1.36e-209 661.0
SHD3_k127_3720042_1 lyase activity K01667 - 4.1.99.1 1.552e-197 627.0
SHD3_k127_3720042_10 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000001876 101.0
SHD3_k127_3720042_2 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 434.0
SHD3_k127_3720042_3 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 330.0
SHD3_k127_3720042_4 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007886 304.0
SHD3_k127_3720042_5 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000000000000000000004001 262.0
SHD3_k127_3720042_6 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
SHD3_k127_3720042_7 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000002488 218.0
SHD3_k127_3720042_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000002449 190.0
SHD3_k127_3720042_9 Part of a membrane complex involved in electron transport - - - 0.0000000000000000000000000000000004865 140.0
SHD3_k127_3721803_0 Sortilin, neurotensin receptor 3, - - - 7.023e-203 648.0
SHD3_k127_3721803_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 559.0
SHD3_k127_3721803_2 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 413.0
SHD3_k127_3721803_3 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 337.0
SHD3_k127_3721803_4 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000003927 226.0
SHD3_k127_3721803_5 Allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000000000000000000000000002043 196.0
SHD3_k127_3721803_6 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000001396 179.0
SHD3_k127_3723897_0 lysine biosynthetic process via aminoadipic acid - - - 1.221e-235 744.0
SHD3_k127_3723897_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 561.0
SHD3_k127_3723897_2 PFAM Beta-lactamase K18988 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 415.0
SHD3_k127_3723897_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001345 239.0
SHD3_k127_3728092_0 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 486.0
SHD3_k127_3728092_1 Fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 427.0
SHD3_k127_3728092_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 289.0
SHD3_k127_3728092_3 Evidence 4 Homologs of previously reported genes of K09700 - - 0.0000000000000000000000000000000000002664 142.0
SHD3_k127_3728092_5 PFAM PRC-barrel domain - - - 0.0000000000000004233 82.0
SHD3_k127_3728092_6 - - - - 0.00000000000504 70.0
SHD3_k127_3734835_0 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 459.0
SHD3_k127_3734835_1 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 288.0
SHD3_k127_3734835_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008601 282.0
SHD3_k127_3734835_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000703 263.0
SHD3_k127_3734835_4 lipopolysaccharide-transporting ATPase activity K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000004605 242.0
SHD3_k127_3734835_5 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000007696 155.0
SHD3_k127_3734835_6 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000005435 124.0
SHD3_k127_3734835_7 helix_turn_helix, Lux Regulon - - - 0.0000000000000006015 86.0
SHD3_k127_3743120_0 Protein of unknown function (DUF1501) - - - 1.705e-196 623.0
SHD3_k127_3743120_1 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 605.0
SHD3_k127_3743120_2 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 306.0
SHD3_k127_3744113_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005529 252.0
SHD3_k127_3744113_1 - - - - 0.000000000000000000000000000000004909 138.0
SHD3_k127_3744113_2 PhoQ Sensor - - - 0.00000000000000000001751 92.0
SHD3_k127_3745544_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 533.0
SHD3_k127_3745544_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 390.0
SHD3_k127_3745544_2 Modulates the polysaccharide chain length of enterobacterial common antigen (ECA) - - - 0.00000000000000000000000000000000000004778 158.0
SHD3_k127_3745544_3 CoA-binding domain - - - 0.0000000000007322 73.0
SHD3_k127_3750029_0 WD40-like Beta Propeller Repeat - - - 3.711e-223 723.0
SHD3_k127_3750029_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 352.0
SHD3_k127_3750029_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000326 256.0
SHD3_k127_3756343_0 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 606.0
SHD3_k127_3757791_0 Sortilin, neurotensin receptor 3, - - - 1.305e-196 624.0
SHD3_k127_3757791_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000001452 216.0
SHD3_k127_3762187_0 protein histidine kinase activity K03407,K12257 - 2.7.13.3 0.0 1314.0
SHD3_k127_3762187_1 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 438.0
SHD3_k127_3762187_2 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000006773 190.0
SHD3_k127_3765253_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1323.0
SHD3_k127_3765253_1 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 2.575e-276 867.0
SHD3_k127_3765253_2 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 611.0
SHD3_k127_3765253_3 NAD synthase K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 306.0
SHD3_k127_3765253_4 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008025 265.0
SHD3_k127_3771555_0 Elongation factor Tu domain 2 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 361.0
SHD3_k127_3771555_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006671 247.0
SHD3_k127_3771555_2 cobalamin-transporting ATPase activity K02014,K16092 - - 0.0000000000000000000000000000000001834 140.0
SHD3_k127_3772708_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 422.0
SHD3_k127_3772708_1 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 374.0
SHD3_k127_3772708_2 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 339.0
SHD3_k127_3772708_3 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 304.0
SHD3_k127_3772708_4 undecaprenyl-phosphate glucose phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006404 286.0
SHD3_k127_3772708_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000008074 179.0
SHD3_k127_3772708_6 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000007235 166.0
SHD3_k127_3772708_7 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.0000000000000000000000000000000000000002184 164.0
SHD3_k127_3772708_8 Modulates the polysaccharide chain length of enterobacterial common antigen (ECA) - - - 0.000000000000000000000000000000008898 141.0
SHD3_k127_3772708_9 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000000000000000009554 127.0
SHD3_k127_3776028_0 Protein kinase domain K12132 - 2.7.11.1 7.466e-213 676.0
SHD3_k127_3776028_1 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 565.0
SHD3_k127_3776028_10 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 357.0
SHD3_k127_3776028_11 tryptophan 2,3-dioxygenase activity K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 303.0
SHD3_k127_3776028_12 creatininase K01470,K22232 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 291.0
SHD3_k127_3776028_13 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000152 255.0
SHD3_k127_3776028_14 chlorophyll binding K02040,K03286,K21218 - - 0.000002092 58.0
SHD3_k127_3776028_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 539.0
SHD3_k127_3776028_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 526.0
SHD3_k127_3776028_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 549.0
SHD3_k127_3776028_5 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 487.0
SHD3_k127_3776028_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 474.0
SHD3_k127_3776028_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 469.0
SHD3_k127_3776028_8 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 424.0
SHD3_k127_3776028_9 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 399.0
SHD3_k127_3799867_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 544.0
SHD3_k127_3799867_1 Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 319.0
SHD3_k127_3804864_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 612.0
SHD3_k127_3804864_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000003851 67.0
SHD3_k127_3806598_0 Putative peptidoglycan binding domain K21470 - - 8.715e-195 623.0
SHD3_k127_3806598_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 322.0
SHD3_k127_3806598_2 - - - - 0.00000000000000000000000000000001195 132.0
SHD3_k127_3806598_3 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000005099 130.0
SHD3_k127_3809455_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 499.0
SHD3_k127_3809455_1 Belongs to the DapA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 363.0
SHD3_k127_381748_0 Carboxypeptidase regulatory-like domain - - - 0.0 1477.0
SHD3_k127_381748_1 metallopeptidase activity K03568 - - 4.864e-230 722.0
SHD3_k127_381748_2 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 492.0
SHD3_k127_381748_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 401.0
SHD3_k127_381748_4 PFAM Peptidase family M49 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 378.0
SHD3_k127_381748_5 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 289.0
SHD3_k127_381748_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 254.0
SHD3_k127_381748_7 - K21429 - - 0.0000000000000000000000000000000000000000000000000000000000000000002571 234.0
SHD3_k127_381748_9 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000785 78.0
SHD3_k127_3826682_0 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 560.0
SHD3_k127_3826682_1 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 529.0
SHD3_k127_3826682_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 395.0
SHD3_k127_3826682_3 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 383.0
SHD3_k127_3826682_4 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000000000000009648 205.0
SHD3_k127_3826938_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 415.0
SHD3_k127_3826938_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 410.0
SHD3_k127_3826938_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000001486 265.0
SHD3_k127_3826938_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000009491 231.0
SHD3_k127_3826938_4 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000001469 208.0
SHD3_k127_3826938_5 Capsule assembly protein Wzi - - - 0.000000000000000000000000000001349 130.0
SHD3_k127_386100_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 372.0
SHD3_k127_386100_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000784 205.0
SHD3_k127_386100_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000001739 136.0
SHD3_k127_3891527_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 473.0
SHD3_k127_3891527_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000005542 148.0
SHD3_k127_3891527_2 MazG nucleotide pyrophosphohydrolase domain - - - 0.00000000000000000000000004317 111.0
SHD3_k127_3891527_3 Methyltransferase domain - - - 0.00000000000000000000002295 109.0
SHD3_k127_3891527_4 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000004437 84.0
SHD3_k127_3894363_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 558.0
SHD3_k127_3903461_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 344.0
SHD3_k127_3903461_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 298.0
SHD3_k127_3903461_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005192 252.0
SHD3_k127_3903461_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000101 221.0
SHD3_k127_3903461_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000242 181.0
SHD3_k127_3911371_0 Domain of unknown function (DUF2172) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 575.0
SHD3_k127_3911371_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000133 265.0
SHD3_k127_3911371_2 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.0000000000000000000000000000328 128.0
SHD3_k127_3930564_0 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000007567 220.0
SHD3_k127_3930564_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000006853 193.0
SHD3_k127_3930564_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000001533 171.0
SHD3_k127_3930564_3 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000002436 128.0
SHD3_k127_3930564_4 - - - - 0.0000000001271 64.0
SHD3_k127_3936102_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1360.0
SHD3_k127_3936102_1 protein histidine kinase activity - - - 8.956e-195 621.0
SHD3_k127_3936102_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000005105 228.0
SHD3_k127_3936102_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000163 128.0
SHD3_k127_3936102_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000002905 99.0
SHD3_k127_3946129_0 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 476.0
SHD3_k127_3946129_1 - - - - 0.000000000000000000000000000000000000000000002208 171.0
SHD3_k127_3946129_2 Elongation factor G, domain IV K02355 - - 0.000000000000000000000005414 102.0
SHD3_k127_3946129_3 Phosphoglycerate mutase family - - - 0.0000000000000464 76.0
SHD3_k127_3946129_4 protein kinase activity K12132 - 2.7.11.1 0.00000000008636 72.0
SHD3_k127_3946129_5 Putative prokaryotic signal transducing protein - - - 0.00000002172 63.0
SHD3_k127_3957442_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 334.0
SHD3_k127_3960648_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 298.0
SHD3_k127_3960648_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000002859 239.0
SHD3_k127_3960648_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000004975 218.0
SHD3_k127_3960648_3 - - - - 0.00003038 51.0
SHD3_k127_3968306_0 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 344.0
SHD3_k127_3968306_1 PFAM Roadblock LC7 family protein K07131 GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 - 0.000006755 55.0
SHD3_k127_3968306_2 Domain of unknown function (DUF4388) - - - 0.0000817 47.0
SHD3_k127_3968306_3 Roadblock/LC7 domain - - - 0.0005863 49.0
SHD3_k127_3975237_0 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 345.0
SHD3_k127_3975237_1 Tetratricopeptide repeat K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000004602 220.0
SHD3_k127_3975237_2 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000006629 217.0
SHD3_k127_3975237_3 Domain of unknown function (DUF892) - - - 0.00000000000000000000000000000000000000000000000000004941 193.0
SHD3_k127_3975237_4 phytoene K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000001028 161.0
SHD3_k127_3975237_5 - - - - 0.000000000000000000000000000000002465 131.0
SHD3_k127_3984533_0 Uncharacterised protein family (UPF0182) K09118 - - 8.402e-230 737.0
SHD3_k127_3984533_1 - - - - 0.000000008114 61.0
SHD3_k127_3990123_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 1.571e-222 701.0
SHD3_k127_3990123_1 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 490.0
SHD3_k127_3990123_2 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 458.0
SHD3_k127_3990123_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000005743 141.0
SHD3_k127_3995835_0 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 288.0
SHD3_k127_3995835_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000002188 233.0
SHD3_k127_3995835_2 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000001003 68.0
SHD3_k127_4035630_0 Aldehyde dehydrogenase family K22187 - - 1.277e-273 847.0
SHD3_k127_4035630_1 Bacterial regulatory protein, Fis family - - - 4.11e-210 662.0
SHD3_k127_4035630_10 - - - - 0.00000000000000000000000000000000000000000000000001081 188.0
SHD3_k127_4035630_11 OmpA family K03640 - - 0.0000000000000000000000000000000000000006661 162.0
SHD3_k127_4035630_12 - - - - 0.00000000003328 76.0
SHD3_k127_4035630_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 633.0
SHD3_k127_4035630_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 482.0
SHD3_k127_4035630_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 465.0
SHD3_k127_4035630_5 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 333.0
SHD3_k127_4035630_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 319.0
SHD3_k127_4035630_7 SMART Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 329.0
SHD3_k127_4035630_8 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000006805 238.0
SHD3_k127_4035630_9 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000002569 218.0
SHD3_k127_4042063_0 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 402.0
SHD3_k127_4042063_1 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 310.0
SHD3_k127_4047998_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1240.0
SHD3_k127_4047998_1 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000001132 180.0
SHD3_k127_4047998_2 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000006666 112.0
SHD3_k127_4058613_0 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 561.0
SHD3_k127_4058613_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 537.0
SHD3_k127_4058613_2 Late embryogenesis abundant protein - - - 0.000000000000000000000000000000000000000000000000000002469 194.0
SHD3_k127_407113_0 Peptidase M15 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 297.0
SHD3_k127_407113_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001808 276.0
SHD3_k127_4072171_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 2.946e-204 641.0
SHD3_k127_4072171_1 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.00000000000000000000000006149 115.0
SHD3_k127_4072171_2 Polysaccharide biosynthesis protein K00059 - 1.1.1.100 0.0000000000000000000001913 99.0
SHD3_k127_4079308_0 GMC oxidoreductase - - - 9.157e-219 692.0
SHD3_k127_4079308_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 506.0
SHD3_k127_4079308_2 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 305.0
SHD3_k127_4079308_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000821 269.0
SHD3_k127_4079308_4 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007982 238.0
SHD3_k127_4079308_5 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000001921 213.0
SHD3_k127_4079308_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000005577 207.0
SHD3_k127_4088910_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.975e-229 717.0
SHD3_k127_4088910_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 559.0
SHD3_k127_4088910_2 cyclic-guanylate-specific phosphodiesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 560.0
SHD3_k127_4088910_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 463.0
SHD3_k127_4088910_4 Conserved TM helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 344.0
SHD3_k127_4088910_5 - - - - 0.000000000000000000000000003795 111.0
SHD3_k127_4088910_6 - - - - 0.00000000000002333 76.0
SHD3_k127_4088910_7 Acetyltransferase (GNAT) family - - - 0.0000004846 59.0
SHD3_k127_4113197_0 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 398.0
SHD3_k127_4113197_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 375.0
SHD3_k127_4113197_2 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000001284 202.0
SHD3_k127_4113197_3 - - - - 0.0000000000000000000000000001235 124.0
SHD3_k127_4113251_0 Domain of unknown function (DUF5117) - - - 0.0 1060.0
SHD3_k127_4113251_1 Peptidase family M48 - - - 0.00000000000000000004642 93.0
SHD3_k127_411795_0 Carboxypeptidase regulatory-like domain - - - 6.292e-212 703.0
SHD3_k127_411795_1 Fumarylacetoacetase N-terminal K01555 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 571.0
SHD3_k127_411795_10 DNA-templated transcription, initiation K03088 - - 0.0000000000000005189 86.0
SHD3_k127_411795_2 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 434.0
SHD3_k127_411795_3 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 379.0
SHD3_k127_411795_4 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 344.0
SHD3_k127_411795_5 histidine-tRNA ligase activity K01892,K02502 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000007909 220.0
SHD3_k127_411795_6 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000000000000000000000000000000000000000000005379 212.0
SHD3_k127_411795_7 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000469 162.0
SHD3_k127_411795_8 - - - - 0.00000000000000000000004062 107.0
SHD3_k127_411795_9 - - - - 0.000000000000000008304 86.0
SHD3_k127_411953_0 IMP dehydrogenase activity K03281 - - 2.836e-239 756.0
SHD3_k127_411953_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 491.0
SHD3_k127_411953_2 Uncharacterised conserved protein (DUF2156) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 388.0
SHD3_k127_411953_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 291.0
SHD3_k127_411953_4 NADPH-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000004375 228.0
SHD3_k127_411953_5 methyltransferase activity - - - 0.000000000000000000000000000000009558 133.0
SHD3_k127_411953_6 - - - - 0.00000000000000000000000000000003349 142.0
SHD3_k127_411953_7 Cysteine-rich CPXCG - - - 0.00000000000000000009861 91.0
SHD3_k127_411953_9 - - - - 0.000000000156 69.0
SHD3_k127_4134518_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 2.923e-278 866.0
SHD3_k127_4134518_1 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 316.0
SHD3_k127_4134518_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000002092 176.0
SHD3_k127_4140677_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 489.0
SHD3_k127_4140677_1 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 367.0
SHD3_k127_4140677_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 302.0
SHD3_k127_4140677_3 AAA domain - - - 0.0001527 46.0
SHD3_k127_4140697_0 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 372.0
SHD3_k127_4140697_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000006227 160.0
SHD3_k127_4140697_2 AAA domain - - - 0.0001527 46.0
SHD3_k127_4143396_0 COG0433 Predicted ATPase K06915 - - 8.217e-219 687.0
SHD3_k127_4143396_1 AAA domain K03546 - - 1.068e-217 703.0
SHD3_k127_4143396_2 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 432.0
SHD3_k127_4143396_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003604 246.0
SHD3_k127_4143396_4 - - - - 0.00000000000000000000000456 113.0
SHD3_k127_4148263_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1487.0
SHD3_k127_4148263_1 Phosphate acetyl/butaryl transferase K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 2.69e-233 728.0
SHD3_k127_4148263_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 532.0
SHD3_k127_4148263_3 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 417.0
SHD3_k127_4148263_4 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 409.0
SHD3_k127_4148263_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 384.0
SHD3_k127_4148263_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 349.0
SHD3_k127_4148263_7 Part of the ABC transporter FtsEX involved in K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 308.0
SHD3_k127_4148263_8 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006961 282.0
SHD3_k127_4148263_9 - - - - 0.0000000000000000000005467 99.0
SHD3_k127_4163358_0 cellulose binding - - - 8.941e-302 939.0
SHD3_k127_4163358_1 Protein conserved in bacteria K09922 - - 0.00000000000000000000000000000000000000000000000000001043 190.0
SHD3_k127_4163358_2 Protein of unknown function (DUF1569) - - - 0.000000000000000000002412 96.0
SHD3_k127_4167074_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 2.446e-194 620.0
SHD3_k127_4167074_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 404.0
SHD3_k127_4167074_2 Protein of unknown function (DUF721) - - - 0.0000000000000000000005809 101.0
SHD3_k127_418239_0 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 414.0
SHD3_k127_418239_1 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000022 89.0
SHD3_k127_4201018_0 Aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 441.0
SHD3_k127_4201018_1 cobalamin binding K22491 - - 0.000000000000000000000000000000000000000000000000004908 193.0
SHD3_k127_4201018_2 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000000000000001318 183.0
SHD3_k127_4201018_3 Iron-regulated membrane protein K00380 - 1.8.1.2 0.00000000000000000000000000000000000000000004374 173.0
SHD3_k127_4201018_4 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000006075 164.0
SHD3_k127_4201018_5 CHAD - - - 0.00000000000000004411 89.0
SHD3_k127_4206535_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006068 272.0
SHD3_k127_4206535_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000836 273.0
SHD3_k127_4206535_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000001272 214.0
SHD3_k127_4206535_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000004289 191.0
SHD3_k127_4206535_4 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000001095 145.0
SHD3_k127_4206535_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000001006 143.0
SHD3_k127_4206535_6 Methyltransferase type 12 - - - 0.000000000000000000005878 108.0
SHD3_k127_4220740_0 Belongs to the glycosyl hydrolase 28 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 578.0
SHD3_k127_4220740_1 unsaturated chondroitin disaccharide hydrolase activity K15532 - 3.2.1.172 0.0000000000000000000000000000000000000000000000001255 183.0
SHD3_k127_4221076_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1300.0
SHD3_k127_4221076_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 405.0
SHD3_k127_4221076_2 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000463 100.0
SHD3_k127_4238890_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 422.0
SHD3_k127_4238890_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 410.0
SHD3_k127_4243095_0 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 584.0
SHD3_k127_4243095_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 341.0
SHD3_k127_4243095_2 Sodium:sulfate symporter transmembrane region K03319 - - 0.00000002654 56.0
SHD3_k127_4249356_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 413.0
SHD3_k127_4249356_1 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 416.0
SHD3_k127_4249356_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 381.0
SHD3_k127_4249356_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000008789 243.0
SHD3_k127_4270756_0 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007911 265.0
SHD3_k127_4270756_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000001043 229.0
SHD3_k127_4270756_2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000005741 217.0
SHD3_k127_4270756_3 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.0000000000000000000002003 99.0
SHD3_k127_4273710_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 493.0
SHD3_k127_4273710_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 410.0
SHD3_k127_4273710_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000002195 180.0
SHD3_k127_4273710_3 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000002551 129.0
SHD3_k127_4273710_4 Chromate resistance exported protein - - - 0.0008703 43.0
SHD3_k127_429541_0 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 542.0
SHD3_k127_429541_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000001951 93.0
SHD3_k127_429541_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000001505 65.0
SHD3_k127_429541_3 - - - - 0.000000001943 65.0
SHD3_k127_4310812_0 exoribonuclease II activity K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 465.0
SHD3_k127_4310812_2 acid phosphatase - - - 0.000000000000000000000000000000005182 139.0
SHD3_k127_4310812_3 Methyltransferase type 11 - - - 0.00000000000000000000000003409 115.0
SHD3_k127_4313018_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1340.0
SHD3_k127_4313018_1 Fructose-bisphosphate aldolase class-II - - - 5.995e-207 653.0
SHD3_k127_4313018_10 - - - - 0.0000000000005376 74.0
SHD3_k127_4313018_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 610.0
SHD3_k127_4313018_3 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 608.0
SHD3_k127_4313018_4 Phosphoglucose isomerase K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 581.0
SHD3_k127_4313018_5 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 375.0
SHD3_k127_4313018_6 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 362.0
SHD3_k127_4313018_7 TipAS antibiotic-recognition domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006568 255.0
SHD3_k127_4313018_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008164 255.0
SHD3_k127_4313018_9 WD40-like Beta Propeller Repeat - - - 0.0000000000000001804 82.0
SHD3_k127_4321815_0 peptidase K01415,K07386 - 3.4.24.71 9.701e-224 702.0
SHD3_k127_4321815_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007809 268.0
SHD3_k127_4321815_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000001701 201.0
SHD3_k127_4321815_3 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000000000009207 125.0
SHD3_k127_4321815_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000002865 89.0
SHD3_k127_4321815_5 Domain of Unknown function (DUF542) K07322 - - 0.0000000001129 65.0
SHD3_k127_4329874_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 6.768e-279 861.0
SHD3_k127_4335082_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.793e-274 848.0
SHD3_k127_4335082_1 Glycosyl transferase 4-like K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 541.0
SHD3_k127_4335082_10 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000219 110.0
SHD3_k127_4335082_11 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000002486 69.0
SHD3_k127_4335082_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 352.0
SHD3_k127_4335082_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 344.0
SHD3_k127_4335082_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 331.0
SHD3_k127_4335082_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000002052 218.0
SHD3_k127_4335082_6 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000009785 204.0
SHD3_k127_4335082_7 ErfK ybiS ycfS ynhG family protein K19234 - - 0.000000000000000000000000000000000000000000000000000009523 196.0
SHD3_k127_4335082_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000005754 159.0
SHD3_k127_4335082_9 - - - - 0.00000000000000000000000000000008902 131.0
SHD3_k127_4338953_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 377.0
SHD3_k127_4338953_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 347.0
SHD3_k127_4338953_2 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 315.0
SHD3_k127_4338953_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 315.0
SHD3_k127_4338953_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 297.0
SHD3_k127_4338953_5 negative regulation of phosphate transmembrane transport K02039 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000242 262.0
SHD3_k127_4339399_0 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 588.0
SHD3_k127_4339399_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000008023 211.0
SHD3_k127_4339399_2 FixH - - - 0.0003847 46.0
SHD3_k127_4340257_0 CobQ CobB MinD ParA nucleotide binding domain K16554,K16692 - - 0.00000000000000000000000000000000000000000000000000000000000000004291 244.0
SHD3_k127_4340257_1 Glycosyl transferase family 4 - - - 0.00000000000000000000006545 110.0
SHD3_k127_4341791_0 ABC transporter K06020 - 3.6.3.25 1.403e-258 807.0
SHD3_k127_4341791_1 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009424 460.0
SHD3_k127_4341791_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009643 331.0
SHD3_k127_4341791_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000202 209.0
SHD3_k127_4341791_4 transcription factor binding - - - 0.00000000000000000000000000000000000000000000000005575 184.0
SHD3_k127_4341791_5 CoA binding domain K06929 - - 0.000000000000000000000000000000000000001069 156.0
SHD3_k127_4341791_7 Haem-binding domain - - - 0.000000000000000002414 93.0
SHD3_k127_4341791_8 Cupin domain - - - 0.0000000000000007621 82.0
SHD3_k127_4341791_9 CHASE3 domain - - - 0.00000005216 61.0
SHD3_k127_4346640_0 Fimbrial assembly protein (PilN) - - - 0.000000000000000000000000000000000000000000000000001409 192.0
SHD3_k127_4346640_1 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000002539 160.0
SHD3_k127_4346640_2 - - - - 0.000000000000000000000000000000000009501 142.0
SHD3_k127_4349318_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 377.0
SHD3_k127_4349318_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 369.0
SHD3_k127_4349318_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 344.0
SHD3_k127_4349318_3 Fe-S metabolism associated domain K02426 - - 0.000000000000000000000000000000000000000000000000000000005875 201.0
SHD3_k127_4349318_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.0000000000000000000000000000000000000000000000000003288 189.0
SHD3_k127_4351437_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 617.0
SHD3_k127_4351437_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003167 282.0
SHD3_k127_4351437_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000001155 230.0
SHD3_k127_436297_0 Reductase C-terminal K05297 - 1.18.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 348.0
SHD3_k127_436297_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000003149 165.0
SHD3_k127_4363020_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.599e-297 924.0
SHD3_k127_4363020_1 May be involved in recombinational repair of damaged DNA K03631 - - 5.577e-229 721.0
SHD3_k127_4363020_2 glucan 1,4-alpha-glucosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 396.0
SHD3_k127_4363020_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 349.0
SHD3_k127_4363020_4 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 325.0
SHD3_k127_4363020_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 311.0
SHD3_k127_4363020_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000001106 76.0
SHD3_k127_4370000_0 ABC transporter transmembrane region K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 487.0
SHD3_k127_4370000_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 315.0
SHD3_k127_4370000_2 phosphorelay signal transduction system - - - 0.000000000000008303 78.0
SHD3_k127_4374184_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1280.0
SHD3_k127_4374184_1 EAL domain - - - 0.00000000000000000000000000000000000000000000000004596 179.0
SHD3_k127_437732_0 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000002441 215.0
SHD3_k127_437732_1 PFAM glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000003243 136.0
SHD3_k127_437732_2 Modulates the polysaccharide chain length of enterobacterial common antigen (ECA) - - - 0.0000000000000196 85.0
SHD3_k127_4378359_0 Sortilin, neurotensin receptor 3, - - - 0.0 1291.0
SHD3_k127_4378359_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 376.0
SHD3_k127_4378359_10 - - - - 0.000001185 58.0
SHD3_k127_4378359_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 347.0
SHD3_k127_4378359_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001199 275.0
SHD3_k127_4378359_4 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000006908 233.0
SHD3_k127_4378359_5 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000001805 207.0
SHD3_k127_4378359_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000001956 205.0
SHD3_k127_4378359_7 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000001693 148.0
SHD3_k127_4391171_0 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008375 424.0
SHD3_k127_4391171_1 Biotin-requiring enzyme - - - 0.00000000000000000000000000000000000000001658 156.0
SHD3_k127_4391171_2 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000007585 124.0
SHD3_k127_4391956_0 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 401.0
SHD3_k127_4394856_0 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 495.0
SHD3_k127_4394856_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 295.0
SHD3_k127_4394856_2 - - - - 0.000000000000000000000000000000000000000000000000000001415 199.0
SHD3_k127_4394856_3 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000009439 196.0
SHD3_k127_4394856_4 B12 binding domain K04034 - 1.21.98.3 0.00000000000000000000504 98.0
SHD3_k127_4394856_5 family 18 - - - 0.0000001455 63.0
SHD3_k127_4414594_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 408.0
SHD3_k127_4414594_1 Putative esterase - - - 0.000000002038 59.0
SHD3_k127_4416837_0 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 465.0
SHD3_k127_4416837_1 Outer membrane lipoprotein K05807 - - 0.0000000000000000000000000000000000000000000000000000000000001424 220.0
SHD3_k127_4416837_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000212 185.0
SHD3_k127_4434022_0 nitrous-oxide reductase activity K00376,K02275 GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 3.605e-318 985.0
SHD3_k127_4434022_1 Putative modulator of DNA gyrase K03568 - - 2.234e-235 739.0
SHD3_k127_4434022_10 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.000000000000000000000000000000000000000003541 159.0
SHD3_k127_4434022_11 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.000000000000000000000000000000006427 133.0
SHD3_k127_4434022_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000008326 74.0
SHD3_k127_4434022_13 Universal stress protein family - - - 0.00000308 57.0
SHD3_k127_4434022_14 Family of unknown function (DUF5335) - - - 0.000004154 56.0
SHD3_k127_4434022_2 Putative modulator of DNA gyrase - - - 2.73e-200 634.0
SHD3_k127_4434022_3 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 493.0
SHD3_k127_4434022_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 450.0
SHD3_k127_4434022_5 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 386.0
SHD3_k127_4434022_6 ATPase activity K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000324 239.0
SHD3_k127_4434022_7 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000001219 207.0
SHD3_k127_4434022_8 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000000000003205 212.0
SHD3_k127_4434022_9 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000003494 198.0
SHD3_k127_4461123_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 450.0
SHD3_k127_4461123_1 cellular manganese ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 370.0
SHD3_k127_4478888_0 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000003155 212.0
SHD3_k127_4478888_1 Rossmann-like domain - - - 0.00000000000000000000000000001399 131.0
SHD3_k127_4478888_2 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000001148 119.0
SHD3_k127_4504288_0 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 393.0
SHD3_k127_4504288_1 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000006518 178.0
SHD3_k127_4504288_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000002294 176.0
SHD3_k127_4504288_3 Domain of unknown function (DUF4321) - - - 0.00000000000000000000000000000000005177 135.0
SHD3_k127_4504288_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000004806 89.0
SHD3_k127_4506353_0 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 327.0
SHD3_k127_4506353_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 303.0
SHD3_k127_4509842_0 TonB dependent receptor K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 325.0
SHD3_k127_4509842_1 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000004186 225.0
SHD3_k127_4509842_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000001103 172.0
SHD3_k127_4509842_3 creatininase K01470 - 3.5.2.10 0.00000000000000000001057 97.0
SHD3_k127_4524527_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.973e-239 751.0
SHD3_k127_4524527_1 B3/4 domain K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 507.0
SHD3_k127_4524527_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 374.0
SHD3_k127_4524527_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 349.0
SHD3_k127_4524527_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000008231 87.0
SHD3_k127_4524527_5 - - - - 0.0000008307 55.0
SHD3_k127_4526027_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 312.0
SHD3_k127_4526027_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000009284 263.0
SHD3_k127_4526027_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000001171 125.0
SHD3_k127_4526027_3 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000015 115.0
SHD3_k127_4538714_0 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 349.0
SHD3_k127_4538714_1 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 296.0
SHD3_k127_4538714_2 - - - - 0.00000000000000000000000000000000000000000000000000006271 198.0
SHD3_k127_4538714_3 - - - - 0.00000000000000000000000000000000004286 144.0
SHD3_k127_4553853_0 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 427.0
SHD3_k127_4553853_1 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 421.0
SHD3_k127_4553853_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 324.0
SHD3_k127_4553853_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000001044 113.0
SHD3_k127_4554102_0 Dehydrogenase K07077 - - 1.051e-285 885.0
SHD3_k127_4554102_1 Prolyl oligopeptidase - - - 1.325e-223 719.0
SHD3_k127_4554102_2 YGGT family K02221 - - 0.000000000000000000000000000000000000000000000000000004231 198.0
SHD3_k127_4554102_3 Belongs to the UPF0235 family K09131 - - 0.00000000000000000001881 99.0
SHD3_k127_4554102_4 EVE domain - - - 0.0000000000000001787 80.0
SHD3_k127_4559714_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 333.0
SHD3_k127_4559714_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001355 253.0
SHD3_k127_4559714_2 Domain of unknown function (DUF4956) - - - 0.000000000000000000000000000000000002895 151.0
SHD3_k127_4559714_3 SdiA-regulated - - - 0.000000000000000000000000000000191 135.0
SHD3_k127_4559714_4 Surface antigen - - - 0.0000000000000000301 87.0
SHD3_k127_4572715_0 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 314.0
SHD3_k127_4572715_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003969 258.0
SHD3_k127_4572715_2 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000001253 133.0
SHD3_k127_4577163_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 472.0
SHD3_k127_4577163_1 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 375.0
SHD3_k127_4577163_2 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000001356 230.0
SHD3_k127_4577163_4 Septum formation initiator K05589 - - 0.00000000000000001497 85.0
SHD3_k127_4577163_5 - - - - 0.00000002159 55.0
SHD3_k127_4577445_0 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 338.0
SHD3_k127_4577445_1 KR domain K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 297.0
SHD3_k127_4577445_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000005678 197.0
SHD3_k127_4577445_3 - - - - 0.000000000000000000000000006128 113.0
SHD3_k127_4577445_4 - - - - 0.00000001037 59.0
SHD3_k127_4622849_0 Amino acid permease K03294 - - 6.423e-202 638.0
SHD3_k127_4622849_1 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000001441 184.0
SHD3_k127_4624892_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 395.0
SHD3_k127_4624892_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 383.0
SHD3_k127_4624892_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000000002136 157.0
SHD3_k127_4635873_0 Sodium:solute symporter family - - - 2.072e-224 705.0
SHD3_k127_4635873_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 7.687e-213 678.0
SHD3_k127_4635873_2 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 464.0
SHD3_k127_4635873_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000003132 203.0
SHD3_k127_4635873_4 Iron-sulphur cluster biosynthesis - - - 0.000000000000000000000000000000000000000000000000001502 188.0
SHD3_k127_4635873_6 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.00000000000000000001369 95.0
SHD3_k127_4641880_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 602.0
SHD3_k127_4641880_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 504.0
SHD3_k127_4641880_2 Nicotinamide mononucleotide transporter K03811 - - 0.00000000000002253 74.0
SHD3_k127_4645303_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 4.83e-232 728.0
SHD3_k127_4645303_1 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 535.0
SHD3_k127_4645303_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000002868 180.0
SHD3_k127_4645303_3 function. Source PGD - - - 0.000000002702 59.0
SHD3_k127_466602_0 coagulation factor 5 8 type - - - 9.347e-286 909.0
SHD3_k127_466602_1 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 1.722e-210 661.0
SHD3_k127_466602_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 415.0
SHD3_k127_466602_3 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000003862 135.0
SHD3_k127_466602_4 23S rRNA-intervening sequence protein - - - 0.0000000000000000001122 93.0
SHD3_k127_4676137_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.385e-219 691.0
SHD3_k127_4676137_1 domain protein K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 505.0
SHD3_k127_4676137_2 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000003024 257.0
SHD3_k127_4676137_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000007358 168.0
SHD3_k127_4676137_4 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00008238 49.0
SHD3_k127_4676137_5 COG0457 FOG TPR repeat - - - 0.0007338 47.0
SHD3_k127_4684_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002288 253.0
SHD3_k127_4684_1 asparaginase activity K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000001851 191.0
SHD3_k127_4684_2 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000001168 150.0
SHD3_k127_4689852_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 272.0
SHD3_k127_4689852_1 CheC-like family K03410 - - 0.000000000000000000000000000000000000000000000524 174.0
SHD3_k127_4689852_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000001684 135.0
SHD3_k127_4689852_3 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000001512 132.0
SHD3_k127_4700163_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 1.892e-263 827.0
SHD3_k127_4705222_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1402.0
SHD3_k127_4705222_1 POT family K03305 - - 1.607e-202 644.0
SHD3_k127_4705222_10 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000003741 214.0
SHD3_k127_4705222_11 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000004509 196.0
SHD3_k127_4705222_12 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000001348 187.0
SHD3_k127_4705222_13 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000001684 196.0
SHD3_k127_4705222_14 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000002488 191.0
SHD3_k127_4705222_15 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000006493 179.0
SHD3_k127_4705222_16 Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000002357 141.0
SHD3_k127_4705222_17 DbpA RNA binding domain K05592 - 3.6.4.13 0.00000000000000001494 89.0
SHD3_k127_4705222_18 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000001214 72.0
SHD3_k127_4705222_19 Protein of unknown function (DUF3108) - - - 0.00000000001734 65.0
SHD3_k127_4705222_2 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 596.0
SHD3_k127_4705222_20 Protein of unknown function (DUF3108) - - - 0.000006736 51.0
SHD3_k127_4705222_3 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 533.0
SHD3_k127_4705222_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 544.0
SHD3_k127_4705222_5 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 505.0
SHD3_k127_4705222_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 457.0
SHD3_k127_4705222_7 Glycosyl transferase family 2 K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 292.0
SHD3_k127_4705222_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001407 279.0
SHD3_k127_4705222_9 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000002307 234.0
SHD3_k127_4707611_0 Clp amino terminal domain, pathogenicity island component K03696 - - 0.0 1418.0
SHD3_k127_4707611_1 Surface antigen K07277 - - 1.623e-259 820.0
SHD3_k127_4719010_0 Bacterial regulatory protein, Fis family - - - 1.618e-211 669.0
SHD3_k127_4719010_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 343.0
SHD3_k127_4719010_2 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000006272 199.0
SHD3_k127_4727347_0 Luciferase-like monooxygenase K17228 - 1.14.14.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 542.0
SHD3_k127_4727347_1 Cellulose synthase K00694 - 2.4.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 540.0
SHD3_k127_4727347_2 Glycosyl hydrolase family 26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 375.0
SHD3_k127_4727347_3 Carbamoyl-phosphate synthase L chain, ATP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 364.0
SHD3_k127_4727347_4 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 326.0
SHD3_k127_4727347_5 Carbamoyl-phosphate synthase L chain, ATP binding domain - - - 0.000000000000000000003245 94.0
SHD3_k127_4727347_7 Tetratricopeptide repeat - - - 0.0000007785 62.0
SHD3_k127_4730865_0 Hypothetical methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 421.0
SHD3_k127_4730865_1 Sigma-70 region 2 K03088 - - 0.000000000009657 66.0
SHD3_k127_4730865_2 Trypsin K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000006102 61.0
SHD3_k127_4733679_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1084.0
SHD3_k127_4742068_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000002743 261.0
SHD3_k127_4742068_1 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000004986 153.0
SHD3_k127_4742068_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000008196 137.0
SHD3_k127_4742068_3 - - - - 0.000000000000000000000000000001679 129.0
SHD3_k127_4743164_0 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000009287 121.0
SHD3_k127_4743164_1 Psort location CytoplasmicMembrane, score - - - 0.000002621 59.0
SHD3_k127_4749600_0 4Fe-4S dicluster domain K00184 - - 0.0 1249.0
SHD3_k127_4749600_1 Polysulphide reductase, NrfD K00185 - - 1.145e-254 794.0
SHD3_k127_4749600_2 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 402.0
SHD3_k127_4749600_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 335.0
SHD3_k127_4749600_4 SpoU rRNA Methylase family K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
SHD3_k127_4749600_5 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001076 274.0
SHD3_k127_4749600_6 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001097 252.0
SHD3_k127_4749600_7 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002611 241.0
SHD3_k127_4749600_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000006541 229.0
SHD3_k127_475906_0 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 605.0
SHD3_k127_475906_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 445.0
SHD3_k127_475906_2 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 413.0
SHD3_k127_475906_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 316.0
SHD3_k127_475906_4 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000008443 231.0
SHD3_k127_475906_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000001072 240.0
SHD3_k127_475906_7 - - - - 0.00000000002788 70.0
SHD3_k127_4767166_0 ABC transporter transmembrane region - - - 2.341e-238 750.0
SHD3_k127_4767166_1 Amidohydrolase family - - - 1.875e-212 669.0
SHD3_k127_4767166_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 443.0
SHD3_k127_4767166_3 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000001679 181.0
SHD3_k127_4767166_4 Cytochrome oxidase assembly protein K02259 - - 0.00000000000001971 76.0
SHD3_k127_4772906_0 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 517.0
SHD3_k127_4772906_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
SHD3_k127_4772906_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000006078 145.0
SHD3_k127_4783697_0 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 390.0
SHD3_k127_4783697_1 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 392.0
SHD3_k127_4783697_2 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001885 275.0
SHD3_k127_4784981_0 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 562.0
SHD3_k127_4784981_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 537.0
SHD3_k127_4784981_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 441.0
SHD3_k127_4784981_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000001074 167.0
SHD3_k127_4784981_4 SNARE associated Golgi protein K01077 - 3.1.3.1 0.000000000000000000000000000000000000000006581 158.0
SHD3_k127_4784981_5 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000000006579 154.0
SHD3_k127_4784981_6 Protein of unknown function (DUF4235) - - - 0.0000007376 54.0
SHD3_k127_4786924_0 Sortilin, neurotensin receptor 3, - - - 2.392e-208 659.0
SHD3_k127_4786924_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 508.0
SHD3_k127_4786924_2 YCII-related domain - - - 0.00000000000000000000000000000003967 129.0
SHD3_k127_47879_0 Carbohydrate family 9 binding domain-like - - - 1.105e-262 836.0
SHD3_k127_47879_1 Belongs to the sigma-70 factor family. ECF subfamily - - - 6.923e-200 630.0
SHD3_k127_47879_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 412.0
SHD3_k127_47879_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 312.0
SHD3_k127_47879_4 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002101 240.0
SHD3_k127_47879_5 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000001118 199.0
SHD3_k127_47879_6 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000000000000000003461 175.0
SHD3_k127_47879_7 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000005906 142.0
SHD3_k127_47879_8 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000001654 137.0
SHD3_k127_47879_9 - - - - 0.000000000000000001329 98.0
SHD3_k127_4819901_0 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 342.0
SHD3_k127_4819901_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000002683 101.0
SHD3_k127_4832958_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 581.0
SHD3_k127_4832958_1 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 402.0
SHD3_k127_4832958_2 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 286.0
SHD3_k127_4832958_3 Protein of unknown function (DUF3761) - - - 0.0000008931 52.0
SHD3_k127_4832958_4 photosystem II stabilization K02237 - - 0.0005655 50.0
SHD3_k127_4861934_0 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 305.0
SHD3_k127_4861934_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 291.0
SHD3_k127_4861934_2 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 284.0
SHD3_k127_4861934_3 RF-1 domain K15034 - - 0.00000000000000000000001059 106.0
SHD3_k127_4861934_4 AcrB/AcrD/AcrF family K03296 - - 0.0000000005847 61.0
SHD3_k127_4897645_0 RecQ zinc-binding K03654 - 3.6.4.12 2.249e-226 715.0
SHD3_k127_4897645_1 Putative RNA methylase family UPF0020 K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 323.0
SHD3_k127_4897645_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 315.0
SHD3_k127_4897645_3 OsmC-like protein K04063 - - 0.000000000000000000000000000000000001625 144.0
SHD3_k127_4897645_4 transcriptional regulator K09017 - - 0.00000000000000000000000000000001721 129.0
SHD3_k127_4906779_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 336.0
SHD3_k127_4906779_1 GIY-YIG type nucleases (URI domain) K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003456 271.0
SHD3_k127_4906779_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000001153 254.0
SHD3_k127_4914679_0 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 434.0
SHD3_k127_4914679_1 B3/4 domain K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 290.0
SHD3_k127_4914730_0 Domain of unknown function (DUF1906) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 301.0
SHD3_k127_4914730_1 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 284.0
SHD3_k127_4914730_2 glucose sorbosone - - - 0.0000000000000004673 89.0
SHD3_k127_4914730_3 Iron-containing alcohol dehydrogenase - - - 0.00000000116 61.0
SHD3_k127_4917494_0 Pfam Major Facilitator Superfamily - - - 3.431e-199 629.0
SHD3_k127_4917494_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 500.0
SHD3_k127_4917494_2 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000001015 224.0
SHD3_k127_4917494_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000006062 203.0
SHD3_k127_4917494_4 copper resistance - - - 0.0000000000000000000000009253 113.0
SHD3_k127_4924103_0 tRNA wobble adenosine to inosine editing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006133 261.0
SHD3_k127_4924103_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004556 242.0
SHD3_k127_4924103_2 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000582 64.0
SHD3_k127_4934932_0 peptidase K01415,K07386 - 3.4.24.71 1.629e-219 700.0
SHD3_k127_4934932_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 345.0
SHD3_k127_4934932_2 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000000003863 190.0
SHD3_k127_4934932_3 phosphatase activity K07025 - - 0.000000000000000000000000000000000000000000000000004903 188.0
SHD3_k127_4934932_4 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000001879 187.0
SHD3_k127_4953289_0 Elongation factor G C-terminus K06207 - - 2.03e-227 710.0
SHD3_k127_4953289_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 520.0
SHD3_k127_4976637_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 509.0
SHD3_k127_4976637_1 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 510.0
SHD3_k127_4976637_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000001362 183.0
SHD3_k127_4976637_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000008728 172.0
SHD3_k127_4980317_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 547.0
SHD3_k127_4980317_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 327.0
SHD3_k127_499018_0 PFAM ABC transporter transmembrane K06147 - - 7.91e-282 876.0
SHD3_k127_499018_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 362.0
SHD3_k127_499018_2 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 318.0
SHD3_k127_499018_3 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006068 272.0
SHD3_k127_499018_4 - - - - 0.00000000000000000000000000000000000000000000000000000000002482 222.0
SHD3_k127_499018_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000001275 155.0
SHD3_k127_499018_6 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000003138 153.0
SHD3_k127_499018_7 Belongs to the bacterial solute-binding protein 9 family - - - 0.0000000000000000000000007823 108.0
SHD3_k127_4992437_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.878e-286 897.0
SHD3_k127_4992437_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 568.0
SHD3_k127_4992437_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 407.0
SHD3_k127_4992437_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 369.0
SHD3_k127_4992437_4 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000001061 162.0
SHD3_k127_4992437_5 - - - - 0.000000000000000006675 91.0
SHD3_k127_4992437_6 phosphorelay signal transduction system - - - 0.00004802 47.0
SHD3_k127_5009864_0 Highly conserved protein containing a thioredoxin domain K06888 - - 9.419e-249 784.0
SHD3_k127_5009864_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 436.0
SHD3_k127_5009864_2 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 358.0
SHD3_k127_504517_0 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 445.0
SHD3_k127_504517_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000003421 130.0
SHD3_k127_504517_2 HupF/HypC family K04653 - - 0.0000000000000000000000004098 109.0
SHD3_k127_504517_3 heat shock protein binding - - - 0.00015 53.0
SHD3_k127_504576_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 396.0
SHD3_k127_504576_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 311.0
SHD3_k127_504576_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 296.0
SHD3_k127_504576_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000002506 276.0
SHD3_k127_5059974_0 hmm pf01609 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007526 258.0
SHD3_k127_5059974_1 Belongs to the UPF0502 family K09915 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00001261 49.0
SHD3_k127_5061206_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 293.0
SHD3_k127_5061206_1 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000003736 180.0
SHD3_k127_5066654_0 Uncharacterised protein family (UPF0182) K09118 - - 4.34e-204 659.0
SHD3_k127_5066654_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 315.0
SHD3_k127_5066654_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000001502 207.0
SHD3_k127_5071220_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1390.0
SHD3_k127_5071220_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 434.0
SHD3_k127_5071220_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 426.0
SHD3_k127_5071220_3 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 404.0
SHD3_k127_5071220_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002935 282.0
SHD3_k127_5071220_5 P2 response regulator binding domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000354 289.0
SHD3_k127_5071220_6 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002892 239.0
SHD3_k127_5071220_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000000004234 233.0
SHD3_k127_5071220_8 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000001768 210.0
SHD3_k127_5071220_9 PFAM CheW domain protein - - - 0.0000000000000317 81.0
SHD3_k127_5071287_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003447 277.0
SHD3_k127_5071287_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000154 255.0
SHD3_k127_5071287_2 lytic transglycosylase activity - - - 0.0000000000000000000004638 106.0
SHD3_k127_5071287_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - 0.00001762 55.0
SHD3_k127_5075611_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 605.0
SHD3_k127_5075611_1 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000001235 203.0
SHD3_k127_5077215_0 DEAD/H associated K03724 - - 2.072e-254 796.0
SHD3_k127_5077215_1 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 521.0
SHD3_k127_5077215_2 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 428.0
SHD3_k127_5077215_3 Replication initiator protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 372.0
SHD3_k127_5086220_0 Outer membrane protein beta-barrel family - - - 1.125e-299 944.0
SHD3_k127_5086220_1 Dehydrogenase - - - 1.112e-199 631.0
SHD3_k127_5086220_10 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000003014 228.0
SHD3_k127_5086220_11 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000009183 223.0
SHD3_k127_5086220_12 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000005975 151.0
SHD3_k127_5086220_13 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000005073 146.0
SHD3_k127_5086220_14 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000006528 144.0
SHD3_k127_5086220_15 SusD family K21572 - - 0.0000000000000000000000000000000644 141.0
SHD3_k127_5086220_16 - - - - 0.00000000000000000000000000000007888 128.0
SHD3_k127_5086220_17 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000002226 120.0
SHD3_k127_5086220_19 Domain of unknown function (DUF4397) - - - 0.0000000368 65.0
SHD3_k127_5086220_2 TonB-linked outer membrane protein, SusC RagA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 589.0
SHD3_k127_5086220_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 494.0
SHD3_k127_5086220_4 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 377.0
SHD3_k127_5086220_5 Beta-lactamase K21469 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 331.0
SHD3_k127_5086220_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 307.0
SHD3_k127_5086220_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 297.0
SHD3_k127_5086220_8 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001739 258.0
SHD3_k127_5086220_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000008923 237.0
SHD3_k127_5092570_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 6.894e-252 794.0
SHD3_k127_5092570_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 561.0
SHD3_k127_5092570_2 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.00000000000000000000000000000000000000000005454 169.0
SHD3_k127_5101592_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 385.0
SHD3_k127_5101592_1 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 344.0
SHD3_k127_5101592_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000001765 225.0
SHD3_k127_5101592_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000001655 130.0
SHD3_k127_5101592_4 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000613 139.0
SHD3_k127_5101592_5 Ribosomal protein L36 K02919 - - 0.000000000000008306 76.0
SHD3_k127_5114851_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 2.541e-307 951.0
SHD3_k127_5114851_1 KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 525.0
SHD3_k127_5114851_10 - - - - 0.000000000000000000000000000000000000000439 154.0
SHD3_k127_5114851_11 - - - - 0.0000000000000000000000000000001082 129.0
SHD3_k127_5114851_2 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 406.0
SHD3_k127_5114851_3 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 357.0
SHD3_k127_5114851_4 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 311.0
SHD3_k127_5114851_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009924 265.0
SHD3_k127_5114851_6 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000121 239.0
SHD3_k127_5114851_7 Oxidoreductase family, NAD-binding Rossmann fold K00118,K13020 - 1.1.1.335,1.1.99.28 0.00000000000000000000000000000000000000000000000000000000001031 220.0
SHD3_k127_5114851_8 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.0000000000000000000000000000000000000000000001936 179.0
SHD3_k127_5114851_9 lipoprotein YddW precursor K01189 - - - 0.0000000000000000000000000000000000000000009869 172.0
SHD3_k127_512300_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1310.0
SHD3_k127_5141833_0 TonB dependent receptor - - - 9.898e-270 854.0
SHD3_k127_5141833_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 353.0
SHD3_k127_5141833_2 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001685 235.0
SHD3_k127_5147011_0 SAF K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 471.0
SHD3_k127_5147011_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000378 288.0
SHD3_k127_5147011_2 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000001918 188.0
SHD3_k127_5157226_0 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 340.0
SHD3_k127_5157226_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000151 260.0
SHD3_k127_5157226_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000003628 183.0
SHD3_k127_5157226_3 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000009214 164.0
SHD3_k127_5157226_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.00000000000000000000000004045 108.0
SHD3_k127_5163597_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 571.0
SHD3_k127_5163597_1 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 414.0
SHD3_k127_5163597_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000145 267.0
SHD3_k127_5163597_3 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000004346 176.0
SHD3_k127_5163658_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001329 293.0
SHD3_k127_5163658_1 Recombinase zinc beta ribbon domain - - - 0.0002962 43.0
SHD3_k127_5170447_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 512.0
SHD3_k127_5170447_1 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 484.0
SHD3_k127_5170447_10 PRC-barrel domain K03886 - - 0.000000126 56.0
SHD3_k127_5170447_2 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 494.0
SHD3_k127_5170447_3 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 390.0
SHD3_k127_5170447_4 4Fe-4S single cluster domain K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 319.0
SHD3_k127_5170447_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 317.0
SHD3_k127_5170447_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000007775 201.0
SHD3_k127_5170447_7 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000003062 171.0
SHD3_k127_5170447_8 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000397 167.0
SHD3_k127_5170447_9 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000952 76.0
SHD3_k127_5175514_0 WD40-like Beta Propeller Repeat - - - 5.416e-306 968.0
SHD3_k127_5175514_1 Amidohydrolase family - - - 2.985e-226 709.0
SHD3_k127_5175514_10 - - - - 0.00000000000000000000000000001558 122.0
SHD3_k127_5175514_11 - - - - 0.000000000000000000003657 101.0
SHD3_k127_5175514_12 Protein kinase domain K12132 - 2.7.11.1 0.000000000000001956 77.0
SHD3_k127_5175514_13 - - - - 0.0000002274 60.0
SHD3_k127_5175514_2 Ribonuclease E/G family K08301 - - 2.367e-212 668.0
SHD3_k127_5175514_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 518.0
SHD3_k127_5175514_4 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 324.0
SHD3_k127_5175514_5 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000001217 234.0
SHD3_k127_5175514_6 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000007648 214.0
SHD3_k127_5175514_7 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000001194 202.0
SHD3_k127_5175514_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000196 160.0
SHD3_k127_5175514_9 Ribosomal L27 protein K02899 - - 0.0000000000000000000000000000000000000001042 151.0
SHD3_k127_5185773_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 372.0
SHD3_k127_5185773_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000003015 112.0
SHD3_k127_519873_0 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 590.0
SHD3_k127_519873_1 Beta-eliminating lyase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 292.0
SHD3_k127_5207677_0 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 582.0
SHD3_k127_5207677_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 383.0
SHD3_k127_5207677_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 320.0
SHD3_k127_5207677_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000002678 188.0
SHD3_k127_5207677_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000005974 175.0
SHD3_k127_5207677_5 - - - - 0.0000000001112 64.0
SHD3_k127_521492_0 Bacterial membrane protein YfhO - - - 3.113e-249 796.0
SHD3_k127_521492_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000002938 204.0
SHD3_k127_521492_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000001372 147.0
SHD3_k127_521492_3 Glycosyl transferases group 1 - - - 0.0001697 46.0
SHD3_k127_5227942_0 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 408.0
SHD3_k127_5227942_1 PFAM ABC transporter related K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 383.0
SHD3_k127_5227942_2 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 301.0
SHD3_k127_5227942_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000008397 177.0
SHD3_k127_5227942_4 Glycosyl transferases group 1 K19424 GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 - 0.000000000000000000000008199 114.0
SHD3_k127_5227942_5 O-methyltransferase activity - - - 0.000000000000000008715 92.0
SHD3_k127_5228308_0 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 327.0
SHD3_k127_5228308_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003164 241.0
SHD3_k127_5228308_2 - - - - 0.0000000000000000000000219 102.0
SHD3_k127_5233331_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.961e-245 761.0
SHD3_k127_5233331_1 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 426.0
SHD3_k127_5233331_2 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 308.0
SHD3_k127_5233331_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001057 282.0
SHD3_k127_5233331_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000003346 230.0
SHD3_k127_5233331_5 3-phosphoshikimate 1-carboxyvinyltransferase activity K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000002038 220.0
SHD3_k127_5237869_0 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 556.0
SHD3_k127_5237869_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 389.0
SHD3_k127_5237869_2 PFAM NAD-dependent epimerase dehydratase K01709 - 4.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 352.0
SHD3_k127_5237869_3 Nucleotidyl transferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 342.0
SHD3_k127_5237869_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism - - - 0.00000000000000000000000000000000000000000000000009736 190.0
SHD3_k127_5237869_5 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000001011 179.0
SHD3_k127_5237869_6 calcium proton exchanger K07300 - - 0.0000000000000000000000000000000000000006406 151.0
SHD3_k127_5237869_7 Methyltransferase - - - 0.000000000000000000000000000001541 125.0
SHD3_k127_5237869_8 Trm112p-like protein K09791 - - 0.0000000000000000000000167 102.0
SHD3_k127_5252357_0 TonB-dependent receptor K02014 - - 3.704e-253 809.0
SHD3_k127_5261185_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 472.0
SHD3_k127_5261185_1 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000007168 195.0
SHD3_k127_5266834_0 Bacterial protein of unknown function (DUF885) - - - 1.594e-227 721.0
SHD3_k127_5266834_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 3.665e-214 672.0
SHD3_k127_5266834_10 SURF1 family K14998 - - 0.0000000000000000000000000000000000000000000000000000000000000006046 226.0
SHD3_k127_5266834_11 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000004062 196.0
SHD3_k127_5266834_13 NUDIX domain - - - 0.000000000000000000000000000000000002329 147.0
SHD3_k127_5266834_14 Prolyl oligopeptidase family K06889 - - 0.00000000304 61.0
SHD3_k127_5266834_15 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity K13991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 - 0.0000008202 59.0
SHD3_k127_5266834_2 Acyl-CoA dehydrogenase, middle domain - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 5.914e-205 657.0
SHD3_k127_5266834_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 608.0
SHD3_k127_5266834_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 409.0
SHD3_k127_5266834_5 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 379.0
SHD3_k127_5266834_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 364.0
SHD3_k127_5266834_7 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 303.0
SHD3_k127_5266834_8 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 304.0
SHD3_k127_5266834_9 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 287.0
SHD3_k127_5272876_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.997e-217 687.0
SHD3_k127_5272876_1 GGDEF domain - - - 0.0000000000000000000000143 104.0
SHD3_k127_5286448_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 512.0
SHD3_k127_5286448_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 359.0
SHD3_k127_5286448_2 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 332.0
SHD3_k127_5286448_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 335.0
SHD3_k127_5286448_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000009095 77.0
SHD3_k127_5298692_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 541.0
SHD3_k127_5298692_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 512.0
SHD3_k127_5298692_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000006876 90.0
SHD3_k127_5303728_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000002299 251.0
SHD3_k127_5303728_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000007718 164.0
SHD3_k127_5303728_2 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000000000000001651 147.0
SHD3_k127_5303728_3 lytic transglycosylase activity - - - 0.000000000000002233 85.0
SHD3_k127_530725_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 1.321e-268 847.0
SHD3_k127_530725_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 1.403e-216 685.0
SHD3_k127_530725_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 507.0
SHD3_k127_530725_3 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 461.0
SHD3_k127_530725_4 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000000000000001312 202.0
SHD3_k127_530725_5 ABC1 family - - - 0.00000000000000001359 85.0
SHD3_k127_530725_6 Selenoprotein, putative - - - 0.00000000000005675 74.0
SHD3_k127_530905_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 374.0
SHD3_k127_530905_1 aminopeptidase N - - - 0.000000000000000000000000000000000005845 154.0
SHD3_k127_530905_2 Peptidase family M28 - - - 0.0000000000000000003013 91.0
SHD3_k127_5316378_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 367.0
SHD3_k127_5316378_1 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 359.0
SHD3_k127_5316378_2 - - - - 0.00000000000000000000000000000000000000000000000001053 191.0
SHD3_k127_5316378_3 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000006209 181.0
SHD3_k127_5326218_0 Collagenase K08303 - - 5.018e-280 877.0
SHD3_k127_5326218_1 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 364.0
SHD3_k127_5326218_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000003623 127.0
SHD3_k127_5350361_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 6.179e-301 934.0
SHD3_k127_5350361_1 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 608.0
SHD3_k127_5350361_2 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 570.0
SHD3_k127_5350361_3 Hsp70 protein K03569 - - 0.00000000000000000000000000000000000008171 142.0
SHD3_k127_5352914_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.041e-225 706.0
SHD3_k127_5352914_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.042e-212 663.0
SHD3_k127_5352914_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 473.0
SHD3_k127_5352914_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001581 254.0
SHD3_k127_5354089_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000134 277.0
SHD3_k127_5354089_1 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000002506 252.0
SHD3_k127_5354089_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000006631 114.0
SHD3_k127_5354995_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 514.0
SHD3_k127_5354995_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 480.0
SHD3_k127_5354995_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000001001 230.0
SHD3_k127_5354995_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000005978 178.0
SHD3_k127_5354995_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000009614 98.0
SHD3_k127_5354995_5 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000001155 80.0
SHD3_k127_5358016_0 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 460.0
SHD3_k127_5358016_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K07077 - - 0.00002177 48.0
SHD3_k127_5364738_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 594.0
SHD3_k127_5364738_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 445.0
SHD3_k127_5364738_2 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000000000000003847 192.0
SHD3_k127_5364738_3 Nucleoside H+ symporter - - - 0.0001682 46.0
SHD3_k127_5367244_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 329.0
SHD3_k127_5367244_1 GDP-mannose 4,6 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000005882 222.0
SHD3_k127_5367244_2 O-acyltransferase activity K00661 - 2.3.1.79 0.000000000000000000000000000000000000002129 154.0
SHD3_k127_5367244_3 Membrane protein involved in the export of O-antigen and teichoic acid K03328 - - 0.00002014 57.0
SHD3_k127_5375034_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 1.047e-232 730.0
SHD3_k127_5385311_0 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 385.0
SHD3_k127_5385311_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 383.0
SHD3_k127_5385311_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 289.0
SHD3_k127_5385311_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000000000000000000000001817 181.0
SHD3_k127_5385311_4 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000000000000005932 179.0
SHD3_k127_5385311_5 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000001285 177.0
SHD3_k127_5385311_6 - - - - 0.000000000000000000000000000000000000000000000001697 186.0
SHD3_k127_5398836_0 dehydrogenase, E1 component K11381 - 1.2.4.4 1.317e-309 962.0
SHD3_k127_5398836_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000001611 114.0
SHD3_k127_540699_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 391.0
SHD3_k127_540699_1 - - - - 0.000000000000000000000000000000000001629 145.0
SHD3_k127_540699_2 Outer membrane protein beta-barrel domain - - - 0.0000000000003332 78.0
SHD3_k127_5425614_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 1.926e-231 722.0
SHD3_k127_5425614_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.413e-222 697.0
SHD3_k127_5425614_2 metalloendopeptidase activity K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 535.0
SHD3_k127_5425614_3 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000004295 156.0
SHD3_k127_5428360_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 312.0
SHD3_k127_5428360_1 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000000000000000246 145.0
SHD3_k127_5428360_2 - - - - 0.000000000000000000000000000000002815 132.0
SHD3_k127_5428360_3 - - - - 0.000000000000001092 81.0
SHD3_k127_5428360_4 - - - - 0.00001217 55.0
SHD3_k127_5429651_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 3.56e-322 1005.0
SHD3_k127_5429651_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 2.052e-254 796.0
SHD3_k127_5429651_2 TonB-dependent receptor - - - 5.549e-223 725.0
SHD3_k127_5429651_3 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 597.0
SHD3_k127_5429651_4 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 460.0
SHD3_k127_5429651_5 transmembrane transport K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 404.0
SHD3_k127_5429651_6 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 363.0
SHD3_k127_5429651_7 Transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 323.0
SHD3_k127_5429651_8 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000003795 101.0
SHD3_k127_5434245_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 586.0
SHD3_k127_5434245_1 isocitrate dehydrogenase activity K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001564 274.0
SHD3_k127_5434245_2 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000000000000000000002562 215.0
SHD3_k127_5437889_0 CarboxypepD_reg-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 539.0
SHD3_k127_5437889_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 330.0
SHD3_k127_5462265_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 340.0
SHD3_k127_5462265_1 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000001238 196.0
SHD3_k127_5466217_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 478.0
SHD3_k127_5466217_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.00000000000000000000000000003888 119.0
SHD3_k127_5468672_0 Bacterial regulatory protein, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 347.0
SHD3_k127_5468672_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000127 113.0
SHD3_k127_5477082_0 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 534.0
SHD3_k127_5477082_1 Belongs to the HpcH HpaI aldolase family K18292 - 4.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 483.0
SHD3_k127_5477082_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000002493 108.0
SHD3_k127_5487428_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 510.0
SHD3_k127_5487428_1 His Kinase A (phosphoacceptor) domain - - - 0.000004938 54.0
SHD3_k127_5489569_0 Cytochrome c-type biogenesis protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 600.0
SHD3_k127_5489569_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 505.0
SHD3_k127_5489569_2 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 369.0
SHD3_k127_5489569_3 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 287.0
SHD3_k127_5489569_4 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000001526 216.0
SHD3_k127_5489569_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000009683 143.0
SHD3_k127_5489569_6 - - - - 0.0000000000000000000000000000000001059 143.0
SHD3_k127_5489569_7 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000002333 140.0
SHD3_k127_5489569_8 subunit of a heme lyase K02198,K02200 - - 0.000000000000000000000002627 108.0
SHD3_k127_5495644_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.076e-319 987.0
SHD3_k127_5495644_1 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000000002969 146.0
SHD3_k127_5498349_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003649 258.0
SHD3_k127_5501603_0 Dehydrogenase - - - 0.0 1003.0
SHD3_k127_5501603_1 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 398.0
SHD3_k127_5501603_10 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000005971 154.0
SHD3_k127_5501603_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000002661 135.0
SHD3_k127_5501603_13 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000003525 87.0
SHD3_k127_5501603_14 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000008244 69.0
SHD3_k127_5501603_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009789 353.0
SHD3_k127_5501603_3 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 309.0
SHD3_k127_5501603_4 Cysteine-rich motif following a subset of SET domains K07117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001134 270.0
SHD3_k127_5501603_5 PFAM DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001268 274.0
SHD3_k127_5501603_6 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000004599 183.0
SHD3_k127_5501603_7 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000002097 179.0
SHD3_k127_5501603_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000002618 158.0
SHD3_k127_5501603_9 - - - - 0.00000000000000000000000000000000000002654 149.0
SHD3_k127_5502822_0 cellulose binding - - - 9.444e-204 641.0
SHD3_k127_5502822_1 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 563.0
SHD3_k127_5502822_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000009654 236.0
SHD3_k127_5523472_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 592.0
SHD3_k127_5523472_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 542.0
SHD3_k127_5523472_10 Ribosomal L32p protein family K02911 - - 0.00000000000000000000000001069 109.0
SHD3_k127_5523472_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 483.0
SHD3_k127_5523472_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 471.0
SHD3_k127_5523472_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 386.0
SHD3_k127_5523472_5 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 321.0
SHD3_k127_5523472_6 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001193 282.0
SHD3_k127_5523472_7 NDK K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000001925 216.0
SHD3_k127_5523472_8 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000001756 210.0
SHD3_k127_5523472_9 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000198 172.0
SHD3_k127_5525792_0 chorismate binding enzyme K02552 - 5.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 385.0
SHD3_k127_5525792_1 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000077 232.0
SHD3_k127_5525792_2 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.00000000000000000000003644 100.0
SHD3_k127_5525792_3 Cupin 2, conserved barrel domain protein - - - 0.0000000009961 64.0
SHD3_k127_5525792_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0001259 47.0
SHD3_k127_5534965_0 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 301.0
SHD3_k127_5534965_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000001165 175.0
SHD3_k127_5534965_2 - - - - 0.0000000000000000002414 95.0
SHD3_k127_5534965_3 Lysin motif - - - 0.0000000000000000003652 91.0
SHD3_k127_5535274_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 440.0
SHD3_k127_5535274_1 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 351.0
SHD3_k127_5535274_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 304.0
SHD3_k127_5535274_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000006089 270.0
SHD3_k127_5535274_4 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000726 78.0
SHD3_k127_5564165_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 2.866e-201 632.0
SHD3_k127_5564165_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 480.0
SHD3_k127_5564165_2 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 382.0
SHD3_k127_5564165_3 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000001253 260.0
SHD3_k127_5564165_4 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000001491 154.0
SHD3_k127_5564165_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000682 87.0
SHD3_k127_5572288_0 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007832 250.0
SHD3_k127_5572288_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000006475 213.0
SHD3_k127_5572288_2 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000003349 198.0
SHD3_k127_5572288_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000186 134.0
SHD3_k127_5572288_4 Glucose inhibited division protein A K21401 - 1.3.99.38 0.0000000000000001748 80.0
SHD3_k127_5600638_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 366.0
SHD3_k127_5600638_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 303.0
SHD3_k127_5600638_2 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000002511 167.0
SHD3_k127_5600638_3 - - - - 0.000000000000000000003543 102.0
SHD3_k127_5600638_4 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00009747 47.0
SHD3_k127_560328_0 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 438.0
SHD3_k127_560328_1 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000001939 219.0
SHD3_k127_560328_2 secondary active sulfate transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000001252 196.0
SHD3_k127_560328_3 HEAT repeats - - - 0.0000000000000000000000000000000000000002096 163.0
SHD3_k127_560328_4 HEAT repeats - - - 0.00000000000000000000000005774 109.0
SHD3_k127_5603727_0 TonB-linked outer membrane protein, SusC RagA family - - - 0.0 1313.0
SHD3_k127_5603727_1 Starch-binding associating with outer membrane - - - 1.218e-251 785.0
SHD3_k127_5603727_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 301.0
SHD3_k127_5603727_3 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001166 281.0
SHD3_k127_5611790_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 529.0
SHD3_k127_5611790_1 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 448.0
SHD3_k127_5611790_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 400.0
SHD3_k127_5611790_3 Major intrinsic protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 287.0
SHD3_k127_5611790_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000006251 130.0
SHD3_k127_5611790_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000003566 102.0
SHD3_k127_5611790_6 - - - - 0.0000004291 56.0
SHD3_k127_5630753_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 528.0
SHD3_k127_5630753_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 513.0
SHD3_k127_5630753_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 485.0
SHD3_k127_5630753_3 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000003681 240.0
SHD3_k127_5630753_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000000000000000000000003135 181.0
SHD3_k127_5630753_5 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000001011 140.0
SHD3_k127_5630753_6 ThiS family K03636 - - 0.000000000000001565 82.0
SHD3_k127_5633326_0 Pfam:SusD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 492.0
SHD3_k127_5633326_1 - - - - 0.00000000000000003053 91.0
SHD3_k127_5633326_2 Domain of unknown function (DUF4397) - - - 0.00000001183 61.0
SHD3_k127_5635708_0 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 345.0
SHD3_k127_5635708_1 Type ii secretion system protein e K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 293.0
SHD3_k127_5635708_2 Flp pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000051 265.0
SHD3_k127_5635708_3 Response regulator, receiver K02282 - - 0.00000000000000000000000000000000000002392 158.0
SHD3_k127_5649553_0 Peptidase family M13 K07386 - - 8.646e-247 778.0
SHD3_k127_5649553_1 PFAM ATP dependent DNA ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 455.0
SHD3_k127_5649553_2 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 331.0
SHD3_k127_5649553_3 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000001633 206.0
SHD3_k127_5649553_4 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.0000000000000000000000000000000000000000000003112 171.0
SHD3_k127_5649553_5 Cold shock protein domain K03704 - - 0.000000000000000000000000000000001096 134.0
SHD3_k127_5649553_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000122 121.0
SHD3_k127_5659163_0 Atp-dependent helicase - - - 0.0 1138.0
SHD3_k127_5659163_1 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 574.0
SHD3_k127_5659163_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000001223 187.0
SHD3_k127_5659163_3 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271,K03272,K03525,K12961 GO:0003674,GO:0005488,GO:0005515,GO:0006275,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0042802,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0065007,GO:0080090,GO:0090329,GO:2000105,GO:2000112 2.7.1.167,2.7.1.33,2.7.7.70,5.3.1.28 0.000000000000000000000000000000000000000000000002059 179.0
SHD3_k127_5659260_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 494.0
SHD3_k127_5659260_1 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 467.0
SHD3_k127_5659260_2 methyltransferase - - - 0.00000000000000000000001846 104.0
SHD3_k127_5690407_0 Sugar (and other) transporter K07058 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 440.0
SHD3_k127_5690407_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 381.0
SHD3_k127_5692716_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 561.0
SHD3_k127_5692716_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001112 281.0
SHD3_k127_5692716_2 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000003612 205.0
SHD3_k127_5692716_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000003473 215.0
SHD3_k127_5692716_4 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000004549 194.0
SHD3_k127_5692716_5 - - - - 0.0000000000000000002855 96.0
SHD3_k127_5692716_6 - - - - 0.0000002742 57.0
SHD3_k127_5692716_7 domain protein - - - 0.0001203 51.0
SHD3_k127_5696497_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1226.0
SHD3_k127_5696497_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.442e-235 743.0
SHD3_k127_5696497_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 593.0
SHD3_k127_5696497_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 543.0
SHD3_k127_5696497_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 426.0
SHD3_k127_5696497_5 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 356.0
SHD3_k127_5696497_6 - K07274 - - 0.00000000000000000000000000000000000000000000000000000000000000000002672 246.0
SHD3_k127_5696497_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005267 229.0
SHD3_k127_5696497_8 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005267 229.0
SHD3_k127_5696497_9 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000001757 218.0
SHD3_k127_5714880_0 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 549.0
SHD3_k127_5714880_1 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 328.0
SHD3_k127_5714880_3 - - - - 0.0000000000000000000000000000000000000000000000000000000001529 207.0
SHD3_k127_5714880_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001005 128.0
SHD3_k127_58355_0 TonB dependent receptor - - - 8.634e-288 915.0
SHD3_k127_58355_1 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000011 272.0
SHD3_k127_58355_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000124 226.0
SHD3_k127_58355_3 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000001095 223.0
SHD3_k127_58355_4 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000001284 202.0
SHD3_k127_58355_5 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000197 162.0
SHD3_k127_583704_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 3.735e-235 735.0
SHD3_k127_583704_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 578.0
SHD3_k127_583704_10 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000001122 194.0
SHD3_k127_583704_11 SAM-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000002797 196.0
SHD3_k127_583704_12 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000002504 184.0
SHD3_k127_583704_13 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000000000000004648 132.0
SHD3_k127_583704_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 426.0
SHD3_k127_583704_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 418.0
SHD3_k127_583704_4 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 404.0
SHD3_k127_583704_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 371.0
SHD3_k127_583704_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004491 287.0
SHD3_k127_583704_7 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008875 244.0
SHD3_k127_583704_8 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000000000000000003786 229.0
SHD3_k127_583704_9 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000101 200.0
SHD3_k127_586025_0 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 458.0
SHD3_k127_586025_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 393.0
SHD3_k127_586025_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000009113 249.0
SHD3_k127_590686_0 PFAM DsrE DsrF-like family K09004 - - 0.00000000000000000000000000000000003141 139.0
SHD3_k127_590686_1 phosphorelay signal transduction system - - - 0.00000000000000000001736 104.0
SHD3_k127_616607_0 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000006628 254.0
SHD3_k127_616607_1 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000007044 256.0
SHD3_k127_616607_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000003264 177.0
SHD3_k127_621491_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1566.0
SHD3_k127_621491_1 PFAM Bile acid sodium symporter K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 534.0
SHD3_k127_621491_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 415.0
SHD3_k127_621491_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 407.0
SHD3_k127_621491_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 334.0
SHD3_k127_621491_5 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000995 282.0
SHD3_k127_621491_6 PFAM aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000002987 198.0
SHD3_k127_623198_0 Aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 512.0
SHD3_k127_623198_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 312.0
SHD3_k127_623198_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007191 274.0
SHD3_k127_623198_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000002114 226.0
SHD3_k127_623198_4 - - - - 0.0000000000000001524 84.0
SHD3_k127_623198_5 PglZ domain - - - 0.0000001251 53.0
SHD3_k127_626919_0 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 531.0
SHD3_k127_626919_1 DeoC/LacD family aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 397.0
SHD3_k127_635996_0 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005712 276.0
SHD3_k127_635996_1 - - - - 0.000000000000000000000002269 106.0
SHD3_k127_635996_2 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000013 91.0
SHD3_k127_635996_3 Ricin-type beta-trefoil - - - 0.000008579 58.0
SHD3_k127_636213_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 610.0
SHD3_k127_636213_1 Hsp70 protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 571.0
SHD3_k127_636213_2 rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007643 274.0
SHD3_k127_636213_3 rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000003202 204.0
SHD3_k127_6402_0 Repeat of Unknown Function (DUF347) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 310.0
SHD3_k127_6402_1 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000003012 166.0
SHD3_k127_6402_2 - - - - 0.00000000000000000001696 97.0
SHD3_k127_6402_3 Abc transporter K05833 - - 0.000000000000000001221 87.0
SHD3_k127_64398_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 592.0
SHD3_k127_64398_1 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 357.0
SHD3_k127_64398_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004889 258.0
SHD3_k127_64398_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000011 235.0
SHD3_k127_64398_4 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000002926 229.0
SHD3_k127_64398_5 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000002659 144.0
SHD3_k127_64398_6 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000002857 124.0
SHD3_k127_648232_0 amine dehydrogenase activity - - - 1.012e-240 768.0
SHD3_k127_648232_1 AMIN domain K02666 - - 6.137e-215 686.0
SHD3_k127_648232_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 401.0
SHD3_k127_661679_0 - - - - 0.0000000000000000000000000000000000000000000000000000001884 197.0
SHD3_k127_661679_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000002842 177.0
SHD3_k127_661679_2 TRANSCRIPTIONal - - - 0.000000000000000000000000000000000007294 139.0
SHD3_k127_68771_0 ABC transporter K02056 - 3.6.3.17 1.121e-203 645.0
SHD3_k127_68771_1 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 501.0
SHD3_k127_68771_2 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 315.0
SHD3_k127_691330_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 591.0
SHD3_k127_691330_1 Domain of unknown function (DUF4198) - - - 0.00000000000000000000000000000000000000000000000001168 190.0
SHD3_k127_691330_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000003969 162.0
SHD3_k127_691330_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000023 115.0
SHD3_k127_691330_4 CHRD domain - - - 0.0000000000000001578 85.0
SHD3_k127_691330_5 - - - - 0.000000000000001575 83.0
SHD3_k127_691330_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000003796 75.0
SHD3_k127_697344_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000004689 241.0
SHD3_k127_697344_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000005379 239.0
SHD3_k127_697344_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000008845 183.0
SHD3_k127_697344_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000009794 140.0
SHD3_k127_697344_4 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000001145 140.0
SHD3_k127_697344_5 - - - - 0.00000000000000002908 94.0
SHD3_k127_703361_0 Phosphoglucose isomerase K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 542.0
SHD3_k127_703361_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000135 143.0
SHD3_k127_706349_0 Participates in both transcription termination and antitermination K02600 - - 1.318e-211 665.0
SHD3_k127_706349_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 612.0
SHD3_k127_706349_2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family - - - 0.000000000000000000004 97.0
SHD3_k127_718216_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1046.0
SHD3_k127_718216_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 473.0
SHD3_k127_718216_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 335.0
SHD3_k127_718216_3 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000003916 211.0
SHD3_k127_718216_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000775 76.0
SHD3_k127_719224_0 response to abiotic stimulus K03086,K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 521.0
SHD3_k127_719224_1 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 448.0
SHD3_k127_719224_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003421 258.0
SHD3_k127_728745_0 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000244 269.0
SHD3_k127_728745_1 - - - - 0.000000000000000000000000000000000000000000000000000002449 205.0
SHD3_k127_728745_2 COG0840 Methyl-accepting chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000001309 198.0
SHD3_k127_728745_3 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000007939 137.0
SHD3_k127_732009_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 321.0
SHD3_k127_732009_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000001275 92.0
SHD3_k127_732009_2 - - - - 0.00000000000004092 82.0
SHD3_k127_733306_0 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 385.0
SHD3_k127_733306_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 330.0
SHD3_k127_733306_2 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 327.0
SHD3_k127_733306_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000002827 73.0
SHD3_k127_733617_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 483.0
SHD3_k127_733617_1 beta-N-acetylglucosaminidase K01197 - 3.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 471.0
SHD3_k127_733617_2 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 305.0
SHD3_k127_733617_3 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000002695 175.0
SHD3_k127_733617_4 Peptidase dimerisation domain K13049 - - 0.00000000000000000000000000009257 120.0
SHD3_k127_739655_0 metallocarboxypeptidase activity K14054 - - 2.508e-230 731.0
SHD3_k127_739655_1 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 375.0
SHD3_k127_739655_2 - - - - 0.0000000000000000000000000000000001314 143.0
SHD3_k127_740452_0 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002776 273.0
SHD3_k127_740452_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000001067 149.0
SHD3_k127_740452_2 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.00000000000003661 76.0
SHD3_k127_742074_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.022e-225 709.0
SHD3_k127_742074_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 3.677e-211 664.0
SHD3_k127_742074_11 Bacterioferritin comigratory protein K03564 - 1.11.1.15 0.000000000405 62.0
SHD3_k127_742074_12 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00001425 47.0
SHD3_k127_742074_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 497.0
SHD3_k127_742074_3 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 440.0
SHD3_k127_742074_4 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 342.0
SHD3_k127_742074_5 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 314.0
SHD3_k127_742074_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 289.0
SHD3_k127_742074_7 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000007676 232.0
SHD3_k127_742074_8 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000004123 209.0
SHD3_k127_742074_9 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000007555 141.0
SHD3_k127_74213_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.029e-251 781.0
SHD3_k127_74213_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 533.0
SHD3_k127_74213_2 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 535.0
SHD3_k127_74213_3 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 294.0
SHD3_k127_74213_4 - - - - 0.000000000000000000000000000000000000000000739 166.0
SHD3_k127_746736_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 556.0
SHD3_k127_746736_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 358.0
SHD3_k127_746736_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000004387 184.0
SHD3_k127_747306_0 Glycosyl hydrolases family 18 - - - 0.0 1153.0
SHD3_k127_747306_1 Penicillin amidase K01434 - 3.5.1.11 2.283e-279 877.0
SHD3_k127_747306_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000001909 124.0
SHD3_k127_747306_11 DNA-binding transcription factor activity - - - 0.0000000000000000000000002916 115.0
SHD3_k127_747306_12 Cupin 2, conserved barrel domain protein K07155 - 1.13.11.24 0.0000000000000000000000004706 110.0
SHD3_k127_747306_13 Activator of Hsp90 ATPase - - - 0.000000000000000007257 83.0
SHD3_k127_747306_14 - - - - 0.00001745 50.0
SHD3_k127_747306_15 - - - - 0.00005036 45.0
SHD3_k127_747306_16 gag-polyprotein putative aspartyl protease - - - 0.000063 54.0
SHD3_k127_747306_2 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 388.0
SHD3_k127_747306_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 306.0
SHD3_k127_747306_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000003143 203.0
SHD3_k127_747306_5 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000004972 179.0
SHD3_k127_747306_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000003333 179.0
SHD3_k127_747306_7 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000166 173.0
SHD3_k127_747306_8 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000000000000001092 144.0
SHD3_k127_747306_9 YCII-related domain - - - 0.00000000000000000000000000000002728 130.0
SHD3_k127_754140_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 368.0
SHD3_k127_754140_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 336.0
SHD3_k127_754140_2 Mur ligase family, glutamate ligase domain K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000003926 175.0
SHD3_k127_754140_3 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000004472 155.0
SHD3_k127_754140_4 Transglycosylase associated protein - - - 0.00000000000000000000000000000009551 126.0
SHD3_k127_754140_5 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000001872 123.0
SHD3_k127_754140_6 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000003017 130.0
SHD3_k127_757728_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.307e-238 745.0
SHD3_k127_757728_1 permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 612.0
SHD3_k127_757728_2 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 562.0
SHD3_k127_757728_3 Dihydroorotate dehydrogenase K17723 GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 387.0
SHD3_k127_757728_4 PFAM amidohydrolase K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 350.0
SHD3_k127_757728_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000003748 104.0
SHD3_k127_757728_6 PFAM nitrogen-fixing NifU domain protein - - - 0.0001543 52.0
SHD3_k127_77079_0 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 0.0 1546.0
SHD3_k127_786432_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 346.0
SHD3_k127_786432_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009622 319.0
SHD3_k127_786432_2 Peptidase family M23 K21472 - - 0.000000000000000000000000000000000000000000003649 172.0
SHD3_k127_792744_0 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 2.336e-232 736.0
SHD3_k127_792744_1 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 588.0
SHD3_k127_792744_2 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 338.0
SHD3_k127_792744_3 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008034 282.0
SHD3_k127_792744_4 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000671 240.0
SHD3_k127_792744_5 DinB family - - - 0.00000000000000000000000000000000000000000000000000000008891 202.0
SHD3_k127_792744_6 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000001141 176.0
SHD3_k127_792744_7 - - - - 0.000000000000000000000000000000000001691 144.0
SHD3_k127_792744_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000001441 108.0
SHD3_k127_795217_0 ABC transporter K06020 - 3.6.3.25 1.207e-226 713.0
SHD3_k127_795217_1 Peptidase family M28 - - - 0.0000000000000000000000003258 119.0
SHD3_k127_79804_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.883e-243 757.0
SHD3_k127_79804_1 Serine dehydratase beta chain K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 351.0
SHD3_k127_79804_2 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.0000000000001812 70.0
SHD3_k127_82775_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 383.0
SHD3_k127_82775_1 Fusaric acid resistance protein-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 398.0
SHD3_k127_82775_2 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006586 258.0
SHD3_k127_82775_3 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000002881 177.0
SHD3_k127_82775_4 Predicted membrane protein (DUF2339) - - - 0.000000000000000000001033 111.0
SHD3_k127_828165_0 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 473.0
SHD3_k127_828165_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 403.0
SHD3_k127_828165_2 COG0346 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000000003612 175.0
SHD3_k127_828165_3 - - - - 0.00000000000000000000000001732 111.0
SHD3_k127_830727_0 Domain of unknown function (DUF5117) - - - 5.402e-255 811.0
SHD3_k127_830727_1 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 471.0
SHD3_k127_830727_2 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000002602 237.0
SHD3_k127_830727_3 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002922 218.0
SHD3_k127_830727_4 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000000000000000000000000000000000001215 181.0
SHD3_k127_830727_5 - - - - 0.000000000000000000000000000000007066 135.0
SHD3_k127_830922_0 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 5.223e-239 748.0
SHD3_k127_830922_1 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 562.0
SHD3_k127_830922_2 DeoC/LacD family aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 440.0
SHD3_k127_830922_3 belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 356.0
SHD3_k127_830922_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000652 291.0
SHD3_k127_830922_5 HAD-hyrolase-like K06019 - 3.6.1.1 0.0000000000000001436 80.0
SHD3_k127_831522_0 Belongs to the bacterial solute-binding protein 9 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006878 293.0
SHD3_k127_831522_1 - - - - 0.000000000000000000000000000000000000000000000007588 185.0
SHD3_k127_832768_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1015.0
SHD3_k127_832768_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 518.0
SHD3_k127_832768_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 513.0
SHD3_k127_832768_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 429.0
SHD3_k127_832768_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 311.0
SHD3_k127_832768_5 4Fe-4S single cluster domain K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008121 252.0
SHD3_k127_832768_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000004631 237.0
SHD3_k127_832768_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000005011 151.0
SHD3_k127_832768_9 23S rRNA-intervening sequence protein - - - 0.000000000000001083 82.0
SHD3_k127_854015_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 593.0
SHD3_k127_854015_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 448.0
SHD3_k127_854015_2 membrane protein, hemolysin III homolog K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002419 259.0
SHD3_k127_862859_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 7.183e-313 971.0
SHD3_k127_862859_1 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 570.0
SHD3_k127_862859_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 424.0
SHD3_k127_862859_3 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 306.0
SHD3_k127_862859_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000001427 221.0
SHD3_k127_862859_5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.00000000000000000000000000000000000000000000000000000008403 199.0
SHD3_k127_862859_6 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000000002201 176.0
SHD3_k127_862859_7 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000005058 162.0
SHD3_k127_862859_8 - - - - 0.00000000000000000001644 95.0
SHD3_k127_862859_9 Lipoprotein K05811 - - 0.0002138 50.0
SHD3_k127_867231_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 1.032e-222 697.0
SHD3_k127_867231_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 537.0
SHD3_k127_867231_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 527.0
SHD3_k127_867231_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 379.0
SHD3_k127_867231_4 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 316.0
SHD3_k127_867231_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001196 252.0
SHD3_k127_867231_6 Zinc finger domain - - - 0.000000000000000003074 95.0
SHD3_k127_867231_7 Zinc finger domain - - - 0.00000000006224 63.0
SHD3_k127_881998_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 448.0
SHD3_k127_881998_1 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000114 209.0
SHD3_k127_881998_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000003259 183.0
SHD3_k127_881998_3 Type II/IV secretion system protein K02669 - - 0.00000006674 57.0
SHD3_k127_884377_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 413.0
SHD3_k127_884377_1 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 328.0
SHD3_k127_884377_10 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000008012 83.0
SHD3_k127_884377_11 LysM domain - - - 0.0000000000001796 82.0
SHD3_k127_884377_12 cytochrome complex assembly - - - 0.0000000000004513 79.0
SHD3_k127_884377_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 313.0
SHD3_k127_884377_3 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006761 278.0
SHD3_k127_884377_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000065 211.0
SHD3_k127_884377_5 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000004693 204.0
SHD3_k127_884377_6 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000001338 173.0
SHD3_k127_884377_7 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000000000127 165.0
SHD3_k127_884377_8 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000007473 138.0
SHD3_k127_884377_9 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925,K07102 - 2.7.1.221 0.000000000000000000000473 96.0
SHD3_k127_886298_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.0 1635.0
SHD3_k127_886298_1 CarboxypepD_reg-like domain - - - 1.612e-228 737.0
SHD3_k127_886298_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 497.0
SHD3_k127_886298_3 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000000000000000000000000000000000000001743 205.0
SHD3_k127_886298_4 - - - - 0.0000003145 58.0
SHD3_k127_886298_5 PSP1 C-terminal conserved region - - - 0.0000007245 51.0
SHD3_k127_895238_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 421.0
SHD3_k127_897340_0 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 494.0
SHD3_k127_897340_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 460.0
SHD3_k127_897340_2 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000001527 179.0
SHD3_k127_902372_0 COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase K01007,K21787 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 612.0
SHD3_k127_902372_1 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 593.0
SHD3_k127_902372_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000006135 234.0
SHD3_k127_903179_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 508.0
SHD3_k127_903179_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000003104 230.0
SHD3_k127_903179_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000005071 158.0
SHD3_k127_903179_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000000000000000000000000005534 121.0
SHD3_k127_924013_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.199e-229 715.0
SHD3_k127_924013_1 Cell cycle protein K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 560.0
SHD3_k127_924013_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 505.0
SHD3_k127_924013_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 446.0
SHD3_k127_924013_4 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 360.0
SHD3_k127_924013_5 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 329.0
SHD3_k127_928318_0 PglZ domain - - - 1.097e-262 814.0
SHD3_k127_928318_1 ABC transporter transmembrane region K11085 - - 5.164e-228 721.0
SHD3_k127_928318_2 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000001458 217.0
SHD3_k127_928318_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000001405 195.0
SHD3_k127_936945_0 Domain of unknown function (DUF5118) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 304.0
SHD3_k127_936945_1 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001945 256.0
SHD3_k127_943122_0 - - - - 4.735e-199 650.0
SHD3_k127_943122_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000001181 54.0
SHD3_k127_943122_2 translation initiation factor activity K06996 - - 0.000001948 51.0
SHD3_k127_969994_0 DEAD/H associated K03724 - - 7.13e-275 870.0
SHD3_k127_969994_1 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 363.0
SHD3_k127_969994_2 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001103 254.0
SHD3_k127_969994_3 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000008919 243.0
SHD3_k127_969994_4 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000007216 121.0
SHD3_k127_971414_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 460.0
SHD3_k127_971414_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000001007 97.0
SHD3_k127_971414_2 Cytidylyltransferase K07257 - - 0.00000000000728 66.0
SHD3_k127_971414_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000001343 59.0
SHD3_k127_976836_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 373.0
SHD3_k127_976836_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 322.0
SHD3_k127_976836_2 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001585 278.0
SHD3_k127_976836_3 GIY-YIG type nucleases (URI domain) K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000961 262.0
SHD3_k127_981053_0 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 497.0
SHD3_k127_981053_1 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000001395 157.0
SHD3_k127_990832_0 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 391.0
SHD3_k127_990832_1 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000001606 210.0
SHD3_k127_990832_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000003942 179.0
SHD3_k127_990832_3 Redoxin - - - 0.00000000000000000000002278 109.0
SHD3_k127_996936_0 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 630.0
SHD3_k127_996936_1 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 508.0
SHD3_k127_996936_2 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 319.0
SHD3_k127_996936_3 Domain of unknown function (DUF4974) K07165 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007397 270.0
SHD3_k127_996936_4 ECF sigma factor K03088 - - 0.000000000000000000000000000002584 123.0
SHD3_k127_996936_6 - - - - 0.0002274 44.0