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Overview

ID MAG03391
Name SHD3_bin.17
Sample SMP0084
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family Gp7-AA6
Genus DAHUXD01
Species
Assembly information
Completeness (%) 61.37
Contamination (%) 2.07
GC content (%) 70.0
N50 (bp) 14,560
Genome size (bp) 2,338,476

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1961

Gene name Description KEGG GOs EC E-value Score Sequence
SHD3_k127_1018842_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 479.0
SHD3_k127_1018842_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 468.0
SHD3_k127_1018842_2 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000000004207 186.0
SHD3_k127_1018842_3 methyltransferase - - - 0.000000000000000000000000000000000000000003273 161.0
SHD3_k127_1018842_4 PFAM PIN domain - - - 0.00000000000000000000000000002166 124.0
SHD3_k127_1018842_5 positive regulation of growth - - - 0.00000000000000000214 87.0
SHD3_k127_1018842_6 Domain of unknown function (DUF4412) - - - 0.00000000000000002135 95.0
SHD3_k127_1031988_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 455.0
SHD3_k127_1031988_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000005471 222.0
SHD3_k127_1031988_2 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000001715 174.0
SHD3_k127_1031988_4 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000001551 135.0
SHD3_k127_108556_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 565.0
SHD3_k127_108556_1 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 506.0
SHD3_k127_108556_10 OsmC-like protein - - - 0.00000000177 70.0
SHD3_k127_108556_11 - - - - 0.00000001133 61.0
SHD3_k127_108556_12 PFAM ferredoxin K08954 - - 0.00004024 51.0
SHD3_k127_108556_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000002198 240.0
SHD3_k127_108556_3 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000008657 183.0
SHD3_k127_108556_4 Cadherin repeats. - - - 0.0000000000000000000000000000000000003095 162.0
SHD3_k127_108556_5 Smr domain - - - 0.0000000000000000002729 95.0
SHD3_k127_108556_6 diguanylate cyclase - - - 0.0000000000000000009712 99.0
SHD3_k127_108556_7 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.000000000000000121 84.0
SHD3_k127_108556_8 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000001042 90.0
SHD3_k127_108556_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000009891 71.0
SHD3_k127_109096_0 aerobic electron transport chain K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 422.0
SHD3_k127_109096_1 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 294.0
SHD3_k127_109096_2 Cytochrome BD ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009448 283.0
SHD3_k127_109096_3 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000003142 185.0
SHD3_k127_109096_4 NUDIX domain - - - 0.000000000000000000000000000000000000001757 154.0
SHD3_k127_109096_5 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000005424 127.0
SHD3_k127_109096_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000000000004948 83.0
SHD3_k127_109096_7 recA bacterial DNA recombination protein - - - 0.00000000001083 76.0
SHD3_k127_1131625_0 PFAM 4Fe-4S K00184,K21308 - - 6.268e-246 812.0
SHD3_k127_1131625_1 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 323.0
SHD3_k127_1131625_2 chaperone-mediated protein folding - - - 0.0000000000005115 81.0
SHD3_k127_1131625_3 Peptidase M56 - - - 0.00000001136 67.0
SHD3_k127_1131625_4 chaperone-mediated protein folding - - - 0.0000339 57.0
SHD3_k127_1138121_0 Sulfate permease family K03321 - - 3.555e-199 636.0
SHD3_k127_1138121_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 599.0
SHD3_k127_1138121_10 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000007328 158.0
SHD3_k127_1138121_11 methyltransferase activity K20444 - - 0.0000000000000000000000000000000003396 149.0
SHD3_k127_1138121_12 TspO/MBR family - - - 0.0000000000000000000000000002462 126.0
SHD3_k127_1138121_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 465.0
SHD3_k127_1138121_3 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 432.0
SHD3_k127_1138121_4 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 422.0
SHD3_k127_1138121_5 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 421.0
SHD3_k127_1138121_6 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000005315 270.0
SHD3_k127_1138121_7 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000001227 238.0
SHD3_k127_1138121_8 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000000000000000000000000000000000008866 205.0
SHD3_k127_1138121_9 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000698 184.0
SHD3_k127_1139834_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 510.0
SHD3_k127_1139834_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 397.0
SHD3_k127_1139834_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 392.0
SHD3_k127_1139834_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 317.0
SHD3_k127_1139834_4 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002593 289.0
SHD3_k127_1139834_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000008509 222.0
SHD3_k127_1139834_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000004626 218.0
SHD3_k127_1139834_7 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000002766 171.0
SHD3_k127_1139834_8 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000002926 70.0
SHD3_k127_1139834_9 Pyruvate phosphate dikinase - - - 0.00001898 56.0
SHD3_k127_1149439_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 8.338e-266 858.0
SHD3_k127_1149439_1 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 458.0
SHD3_k127_1149439_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000007082 126.0
SHD3_k127_1149439_11 Transglutaminase-like superfamily - - - 0.00000004133 66.0
SHD3_k127_1149439_12 PFAM Outer membrane K06142 - - 0.000001662 57.0
SHD3_k127_1149439_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 337.0
SHD3_k127_1149439_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 317.0
SHD3_k127_1149439_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000195 308.0
SHD3_k127_1149439_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008246 269.0
SHD3_k127_1149439_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000001757 262.0
SHD3_k127_1149439_7 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001867 254.0
SHD3_k127_1149439_8 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000001525 188.0
SHD3_k127_1149439_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000002971 145.0
SHD3_k127_1150237_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 587.0
SHD3_k127_1150237_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 532.0
SHD3_k127_1150237_2 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004568 285.0
SHD3_k127_1150237_3 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000002978 210.0
SHD3_k127_1150237_4 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000009408 179.0
SHD3_k127_1150237_5 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000004723 123.0
SHD3_k127_1155780_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 7.86e-277 894.0
SHD3_k127_1155780_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 2.607e-223 709.0
SHD3_k127_1155780_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 371.0
SHD3_k127_1155780_3 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000003887 243.0
SHD3_k127_1155780_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000001732 174.0
SHD3_k127_1155780_5 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000341 166.0
SHD3_k127_1200481_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 499.0
SHD3_k127_1200481_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 458.0
SHD3_k127_1200481_10 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000001918 164.0
SHD3_k127_1200481_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000001053 161.0
SHD3_k127_1200481_12 domain, Protein - - - 0.0000000000000000000000000000002472 143.0
SHD3_k127_1200481_13 GDP-mannose mannosyl hydrolase activity K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.0000000000000000000000000007778 132.0
SHD3_k127_1200481_14 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000133 128.0
SHD3_k127_1200481_15 Mechanosensitive ion channel - - - 0.000000000000000000000002015 117.0
SHD3_k127_1200481_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000558 103.0
SHD3_k127_1200481_17 Domain of unknown function (DUF4115) - - - 0.0000000000000000000224 100.0
SHD3_k127_1200481_18 - - - - 0.0000000000000000000327 103.0
SHD3_k127_1200481_19 - - - - 0.000000000002509 80.0
SHD3_k127_1200481_2 ATP-dependent helicase activity K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 391.0
SHD3_k127_1200481_20 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000006247 71.0
SHD3_k127_1200481_3 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 391.0
SHD3_k127_1200481_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006096 289.0
SHD3_k127_1200481_5 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000003586 254.0
SHD3_k127_1200481_6 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000001964 231.0
SHD3_k127_1200481_7 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000016 235.0
SHD3_k127_1200481_8 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000004618 224.0
SHD3_k127_1200481_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000002524 171.0
SHD3_k127_122422_0 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 333.0
SHD3_k127_122422_1 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 312.0
SHD3_k127_122422_2 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001967 306.0
SHD3_k127_122422_3 Cyclopropane fatty acid synthase and related methyltransferases - - - 0.0000000000000000000000000000000000000000382 160.0
SHD3_k127_122422_4 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000007185 168.0
SHD3_k127_122422_5 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000004879 124.0
SHD3_k127_122422_6 Pilus assembly protein K02662 - - 0.000000008468 68.0
SHD3_k127_122422_7 PFAM Fimbrial assembly family protein K02663 - - 0.00000003156 66.0
SHD3_k127_122422_8 general secretion pathway protein K02456,K02650 - - 0.0000001351 64.0
SHD3_k127_1303765_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 589.0
SHD3_k127_1303765_1 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 537.0
SHD3_k127_1303765_11 PFAM ferredoxin - - - 0.0000002642 63.0
SHD3_k127_1303765_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 451.0
SHD3_k127_1303765_3 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 340.0
SHD3_k127_1303765_4 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007993 291.0
SHD3_k127_1303765_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001875 265.0
SHD3_k127_1303765_6 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000007938 211.0
SHD3_k127_1303765_7 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000006575 203.0
SHD3_k127_1303765_8 Aminotransferase - - - 0.0000000000000000000000000000000000476 140.0
SHD3_k127_1303765_9 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000001674 136.0
SHD3_k127_1330688_0 Prolyl oligopeptidase - - - 1.546e-260 818.0
SHD3_k127_1330688_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 5.578e-209 668.0
SHD3_k127_1330688_10 COGs COG0783 DNA-binding ferritin-like protein (oxidative damage protectant) K04047 - - 0.00000000000000000000000000000000000000000000000006297 194.0
SHD3_k127_1330688_11 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704 5.4.99.5 0.000000000000000000000000000000000001049 142.0
SHD3_k127_1330688_12 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K02759,K03478 - 2.7.1.196,2.7.1.205,3.5.1.105 0.0000000000000000000000000000000007039 140.0
SHD3_k127_1330688_13 Prephenate dehydrogenase K00210,K00211,K00220,K02013,K04517,K14187 GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,1.3.1.13,1.3.1.43,3.6.3.34,5.4.99.5 0.0000000000000000000000000000001467 141.0
SHD3_k127_1330688_14 Belongs to the UPF0337 (CsbD) family - - - 0.0000002078 56.0
SHD3_k127_1330688_2 Ammonium Transporter K03320 - - 3.477e-203 639.0
SHD3_k127_1330688_3 Peptidase dimerisation domain K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 499.0
SHD3_k127_1330688_4 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 433.0
SHD3_k127_1330688_5 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005329 277.0
SHD3_k127_1330688_6 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000001812 232.0
SHD3_k127_1330688_7 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000002721 200.0
SHD3_k127_1330688_8 Ligand-gated ion channel - - - 0.000000000000000000000000000000000000000000000000000002266 219.0
SHD3_k127_1330688_9 amine oxidase K00276 - 1.4.3.21 0.00000000000000000000000000000000000000000000000001926 197.0
SHD3_k127_1334751_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 507.0
SHD3_k127_1334751_1 Associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 355.0
SHD3_k127_1334751_10 Bacterial Ig-like domain (group 3) K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000000000000000000000001433 164.0
SHD3_k127_1334751_11 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000185 90.0
SHD3_k127_1334751_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 332.0
SHD3_k127_1334751_3 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 311.0
SHD3_k127_1334751_4 metallochaperone-like domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003371 278.0
SHD3_k127_1334751_5 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000005574 246.0
SHD3_k127_1334751_6 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002513 242.0
SHD3_k127_1334751_7 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520,K11177 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000009893 218.0
SHD3_k127_1334751_8 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000003894 215.0
SHD3_k127_1334751_9 MobA-Related Protein K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000002021 178.0
SHD3_k127_1354146_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 6.821e-218 693.0
SHD3_k127_1354146_1 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 455.0
SHD3_k127_1354146_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000272 245.0
SHD3_k127_1354146_3 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000000000000004838 200.0
SHD3_k127_1354146_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000004089 198.0
SHD3_k127_1354146_5 photosystem II stabilization - - - 0.000000000000000000000000000000009863 139.0
SHD3_k127_1354146_6 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000007944 84.0
SHD3_k127_1354146_7 peptidyl-tyrosine sulfation - - - 0.00000000001615 72.0
SHD3_k127_1354146_8 DNA uptake protein and related DNA-binding K02237 - - 0.000000577 61.0
SHD3_k127_1377791_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 386.0
SHD3_k127_1377791_1 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 348.0
SHD3_k127_1377791_2 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 349.0
SHD3_k127_1377791_3 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 351.0
SHD3_k127_1377791_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000001095 177.0
SHD3_k127_1377791_5 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000000000006497 144.0
SHD3_k127_1377791_6 TPR repeat - - - 0.0000001833 64.0
SHD3_k127_1377791_7 domain, Protein - - - 0.000002098 61.0
SHD3_k127_1377791_8 Type II transport protein GspH K08084 - - 0.00002216 53.0
SHD3_k127_1496266_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 482.0
SHD3_k127_1496266_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 465.0
SHD3_k127_1496266_10 - - - - 0.00000000000000000000000000003823 120.0
SHD3_k127_1496266_11 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000533 119.0
SHD3_k127_1496266_12 Competence protein - - - 0.00000000000000000008283 103.0
SHD3_k127_1496266_13 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000009297 77.0
SHD3_k127_1496266_14 SdrD B-like domain - - - 0.0002449 55.0
SHD3_k127_1496266_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 424.0
SHD3_k127_1496266_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 394.0
SHD3_k127_1496266_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 335.0
SHD3_k127_1496266_5 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 306.0
SHD3_k127_1496266_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000006152 195.0
SHD3_k127_1496266_7 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000008719 148.0
SHD3_k127_1496266_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000003373 128.0
SHD3_k127_1496266_9 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000004752 130.0
SHD3_k127_1511514_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 421.0
SHD3_k127_1511514_1 - K12065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 332.0
SHD3_k127_1511514_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000007068 198.0
SHD3_k127_1511514_3 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000001625 144.0
SHD3_k127_1511514_4 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.000000000000000000000000000000000006718 147.0
SHD3_k127_1511514_5 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000004141 137.0
SHD3_k127_1511514_7 Protein involved in meta-pathway of phenol degradation - - - 0.0001954 50.0
SHD3_k127_152259_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1258.0
SHD3_k127_152259_1 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 366.0
SHD3_k127_152259_10 lipase activity K15349 - - 0.000000000000000000000000000000001093 148.0
SHD3_k127_152259_11 von Willebrand factor, type A - - - 0.000000000000000000000000000001382 141.0
SHD3_k127_152259_12 GGDEF domain K21019 - 2.7.7.65 0.0000000000000000000000000003641 128.0
SHD3_k127_152259_13 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000003536 105.0
SHD3_k127_152259_14 Tetratricopeptide repeat - - - 0.0000000009596 73.0
SHD3_k127_152259_2 Dihydroxyacetone kinase family K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 310.0
SHD3_k127_152259_3 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005353 246.0
SHD3_k127_152259_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000002627 219.0
SHD3_k127_152259_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000001771 204.0
SHD3_k127_152259_6 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000009535 182.0
SHD3_k127_152259_7 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000004893 171.0
SHD3_k127_152259_8 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000002116 156.0
SHD3_k127_152259_9 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000002042 147.0
SHD3_k127_1547017_0 WD40-like Beta Propeller Repeat - - - 5.957e-227 731.0
SHD3_k127_1547017_1 GvpD gas vesicle protein K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 531.0
SHD3_k127_1547017_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 506.0
SHD3_k127_1547017_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 446.0
SHD3_k127_1547017_4 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 417.0
SHD3_k127_1547017_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008183 275.0
SHD3_k127_1547017_6 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000004393 199.0
SHD3_k127_1547017_7 Bacterial membrane protein, YfhO - - - 0.0000000007455 72.0
SHD3_k127_1547017_8 - - - - 0.000003923 56.0
SHD3_k127_1547017_9 Bacterial membrane protein YfhO - - - 0.000991 52.0
SHD3_k127_158241_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 528.0
SHD3_k127_158241_1 acetamidase formamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 340.0
SHD3_k127_158241_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000628 183.0
SHD3_k127_158241_11 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000002546 180.0
SHD3_k127_158241_12 arylsulfatase A - - - 0.000000000000000000000000000000000000001022 171.0
SHD3_k127_158241_13 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000003816 151.0
SHD3_k127_158241_14 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000001501 136.0
SHD3_k127_158241_15 thyroxine 5'-deiodinase activity K01562 GO:0003674,GO:0003824,GO:0004800,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006575,GO:0006590,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008430,GO:0009987,GO:0010817,GO:0016020,GO:0016491,GO:0018958,GO:0042403,GO:0042445,GO:0044237,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901360,GO:1901564,GO:1901615 1.21.99.4 0.0000000000000000000000000000001617 127.0
SHD3_k127_158241_16 TIGRFAM Por secretion system C-terminal sorting domain - - - 0.00000000000000000000000002248 126.0
SHD3_k127_158241_17 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.00000000000000000000000004641 111.0
SHD3_k127_158241_18 Transcriptional regulatory protein, C terminal - - - 0.00000000000000077 80.0
SHD3_k127_158241_19 PFAM PKD domain containing protein - - - 0.00000000000002324 87.0
SHD3_k127_158241_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001541 282.0
SHD3_k127_158241_20 Predicted membrane protein (DUF2127) - - - 0.0000000003943 68.0
SHD3_k127_158241_21 Universal stress protein family - - - 0.0000002753 52.0
SHD3_k127_158241_3 PFAM Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001414 254.0
SHD3_k127_158241_4 Transposase K02557,K07484,K13924,K21471 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000002875 263.0
SHD3_k127_158241_5 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000000000000000000000000000000000002797 240.0
SHD3_k127_158241_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.00000000000000000000000000000000000000000000000000007733 204.0
SHD3_k127_158241_9 TIGRFAM polysaccharide pyruvyl transferase CsaB - - - 0.00000000000000000000000000000000000000000000164 191.0
SHD3_k127_1639210_0 ABC transporter, transmembrane K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 613.0
SHD3_k127_1639210_1 ABC transporter transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 389.0
SHD3_k127_1639210_2 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 300.0
SHD3_k127_1639210_3 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000008914 218.0
SHD3_k127_1639210_4 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000009099 168.0
SHD3_k127_1639210_5 ABC transporter substrate-binding protein PnrA-like K02058,K05519,K07335 - - 0.000000008634 58.0
SHD3_k127_1660651_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.31e-275 870.0
SHD3_k127_1660651_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000004352 264.0
SHD3_k127_1660651_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000004002 224.0
SHD3_k127_1660651_3 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000003985 138.0
SHD3_k127_1660651_4 PBS lyase HEAT-like repeat - - - 0.00000000000000000000001661 117.0
SHD3_k127_1664880_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 621.0
SHD3_k127_1664880_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002203 280.0
SHD3_k127_1664880_2 KR domain K07535 - - 0.000000000000000000000000000000000000000000007251 180.0
SHD3_k127_1664880_3 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000001607 168.0
SHD3_k127_1664880_4 Transglycosylase associated protein - - - 0.00000000000000000000000000005333 117.0
SHD3_k127_1664880_5 Putative restriction endonuclease - - - 0.00000000000000000000000001513 111.0
SHD3_k127_1664880_6 esterase K01070 - 3.1.2.12 0.000000000000000000000000169 121.0
SHD3_k127_1664880_7 - - - - 0.000006563 57.0
SHD3_k127_167778_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 620.0
SHD3_k127_167778_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 587.0
SHD3_k127_167778_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 590.0
SHD3_k127_167778_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 544.0
SHD3_k127_167778_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 530.0
SHD3_k127_167778_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 336.0
SHD3_k127_167778_6 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 309.0
SHD3_k127_167778_7 Transport permease protein - - - 0.0000000000000000000000000001367 134.0
SHD3_k127_167778_9 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000001413 95.0
SHD3_k127_1695148_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.116e-241 772.0
SHD3_k127_1695148_1 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 445.0
SHD3_k127_1695148_3 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000001385 247.0
SHD3_k127_1695148_4 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.0000000000000000000000000000000000000000000000000008117 196.0
SHD3_k127_1695148_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000003017 194.0
SHD3_k127_1695148_6 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000007983 159.0
SHD3_k127_1695148_7 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000001588 130.0
SHD3_k127_1695148_9 arylamine N-acetyltransferase activity - - - 0.00000000002569 76.0
SHD3_k127_1726563_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 1.671e-220 713.0
SHD3_k127_1726563_1 Response regulator receiver - - - 4.342e-194 615.0
SHD3_k127_1726563_10 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 349.0
SHD3_k127_1726563_11 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 338.0
SHD3_k127_1726563_12 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003124 275.0
SHD3_k127_1726563_13 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000006612 198.0
SHD3_k127_1726563_14 DinB family - - - 0.0000000000000000000000000000000000000000000000000000455 192.0
SHD3_k127_1726563_15 COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA K06169 - - 0.0000000000000000000000000000000000000000000000000000738 194.0
SHD3_k127_1726563_16 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000004456 147.0
SHD3_k127_1726563_17 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000074 156.0
SHD3_k127_1726563_18 Mo-molybdopterin cofactor metabolic process K03636,K21147 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 0.000000000000003909 90.0
SHD3_k127_1726563_19 efflux transmembrane transporter activity - - - 0.00000000002926 64.0
SHD3_k127_1726563_2 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 621.0
SHD3_k127_1726563_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 614.0
SHD3_k127_1726563_4 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 515.0
SHD3_k127_1726563_5 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 545.0
SHD3_k127_1726563_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 494.0
SHD3_k127_1726563_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 503.0
SHD3_k127_1726563_8 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 486.0
SHD3_k127_1726563_9 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 452.0
SHD3_k127_1757353_0 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 547.0
SHD3_k127_1757353_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 515.0
SHD3_k127_1757353_10 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002477 225.0
SHD3_k127_1757353_11 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000008703 213.0
SHD3_k127_1757353_12 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000001591 218.0
SHD3_k127_1757353_13 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000426 146.0
SHD3_k127_1757353_14 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000005542 148.0
SHD3_k127_1757353_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000002375 147.0
SHD3_k127_1757353_16 Cation efflux family - - - 0.0000000000000000003989 99.0
SHD3_k127_1757353_17 methyltransferase activity K04786,K12240,K13613,K15677 - - 0.0000000000000000005936 97.0
SHD3_k127_1757353_18 Putative Fe-S cluster K00380 - 1.8.1.2 0.00000000000000002434 96.0
SHD3_k127_1757353_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 411.0
SHD3_k127_1757353_20 His Kinase A (phosphoacceptor) domain - - - 0.0004048 53.0
SHD3_k127_1757353_21 - - - - 0.0006552 52.0
SHD3_k127_1757353_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 406.0
SHD3_k127_1757353_4 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 354.0
SHD3_k127_1757353_5 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 320.0
SHD3_k127_1757353_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 315.0
SHD3_k127_1757353_7 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 314.0
SHD3_k127_1757353_8 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000003386 250.0
SHD3_k127_1757353_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000002386 236.0
SHD3_k127_1795591_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 7.407e-218 693.0
SHD3_k127_1795591_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 573.0
SHD3_k127_1795591_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 466.0
SHD3_k127_1795591_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 385.0
SHD3_k127_1795591_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000006738 250.0
SHD3_k127_1795591_5 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000001535 266.0
SHD3_k127_1795591_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000004375 133.0
SHD3_k127_1795591_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000003256 126.0
SHD3_k127_1795591_8 peptidyl-tyrosine sulfation - - - 0.00000000002267 72.0
SHD3_k127_1795591_9 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0001997 51.0
SHD3_k127_182492_0 cellulose binding - - - 0.0 1116.0
SHD3_k127_182492_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 456.0
SHD3_k127_182492_10 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003059 252.0
SHD3_k127_182492_11 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000009183 223.0
SHD3_k127_182492_12 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000000000002608 158.0
SHD3_k127_182492_13 xylan catabolic process - - - 0.00000000000000000000000000000000000000001766 170.0
SHD3_k127_182492_14 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000001183 144.0
SHD3_k127_182492_15 - - - - 0.0000000000000000000000000586 113.0
SHD3_k127_182492_16 - - - - 0.0000000000000000000008337 109.0
SHD3_k127_182492_17 - - - - 0.000000000004869 70.0
SHD3_k127_182492_18 FecR protein - - - 0.000004584 59.0
SHD3_k127_182492_19 - - - - 0.0005723 46.0
SHD3_k127_182492_2 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 421.0
SHD3_k127_182492_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 422.0
SHD3_k127_182492_4 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 394.0
SHD3_k127_182492_5 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 380.0
SHD3_k127_182492_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002188 287.0
SHD3_k127_182492_7 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003686 290.0
SHD3_k127_182492_8 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002836 286.0
SHD3_k127_182492_9 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000309 274.0
SHD3_k127_1830773_0 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 424.0
SHD3_k127_1830773_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 324.0
SHD3_k127_1830773_2 DinB superfamily K07552 - - 0.000000000000000000000000000000000003672 146.0
SHD3_k127_1830773_3 chaperone-mediated protein folding - - - 0.0000000003228 72.0
SHD3_k127_1830773_4 - K03646 - - 0.00006972 55.0
SHD3_k127_1847747_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.928e-199 636.0
SHD3_k127_1847747_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000001952 270.0
SHD3_k127_1847747_2 Cytidylate kinase K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000001071 188.0
SHD3_k127_1847747_3 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000007592 171.0
SHD3_k127_1847747_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000555 124.0
SHD3_k127_1847747_5 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000115 82.0
SHD3_k127_1847747_6 - - - - 0.0000000000002007 80.0
SHD3_k127_1847747_7 ABC transporter K11085 - - 0.000007652 59.0
SHD3_k127_1851336_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 9.008e-196 640.0
SHD3_k127_1851336_1 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 551.0
SHD3_k127_1851336_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 426.0
SHD3_k127_1851336_3 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 379.0
SHD3_k127_1851336_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000001315 240.0
SHD3_k127_1851336_5 Cephalosporin hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000001731 239.0
SHD3_k127_1851336_6 oxidoreductase activity - - - 0.0000000000000000000003457 112.0
SHD3_k127_1851336_7 Domain of unknown function (DUF4388) - - - 0.00000004073 67.0
SHD3_k127_1851336_8 Signal transduction protein - - - 0.00006932 57.0
SHD3_k127_1871041_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 533.0
SHD3_k127_1871041_1 ATPase activity K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 439.0
SHD3_k127_1871041_10 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000002068 158.0
SHD3_k127_1871041_11 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000006318 152.0
SHD3_k127_1871041_12 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.0000000000000000000000000000000008097 150.0
SHD3_k127_1871041_13 TRANSCRIPTIONal - - - 0.00000000000000000000000000000001607 130.0
SHD3_k127_1871041_14 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.00000000000000000000000000001799 123.0
SHD3_k127_1871041_15 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000003285 112.0
SHD3_k127_1871041_16 nuclear chromosome segregation - - - 0.0000000000000000000000001192 121.0
SHD3_k127_1871041_17 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000006234 90.0
SHD3_k127_1871041_18 YGGT family K02221 - - 0.0000000000000009953 90.0
SHD3_k127_1871041_19 C4-type zinc ribbon domain K07164 - - 0.000000000000005812 85.0
SHD3_k127_1871041_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 379.0
SHD3_k127_1871041_20 PFAM DivIVA K04074 - - 0.000000000007102 69.0
SHD3_k127_1871041_21 - - - - 0.00001089 57.0
SHD3_k127_1871041_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 335.0
SHD3_k127_1871041_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000001404 235.0
SHD3_k127_1871041_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000002045 212.0
SHD3_k127_1871041_6 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000001366 205.0
SHD3_k127_1871041_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000003315 206.0
SHD3_k127_1871041_8 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000002034 196.0
SHD3_k127_1871041_9 ATPase-coupled sulfate transmembrane transporter activity K02046,K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000007275 196.0
SHD3_k127_1966546_0 Major facilitator superfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 609.0
SHD3_k127_1966546_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 608.0
SHD3_k127_1966546_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 482.0
SHD3_k127_1966546_3 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001306 281.0
SHD3_k127_1966546_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000009719 141.0
SHD3_k127_1966546_5 oxidoreductase activity, acting on CH-OH group of donors - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000004464 117.0
SHD3_k127_1966546_6 - - - - 0.00000000000009899 80.0
SHD3_k127_1966546_7 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000002673 74.0
SHD3_k127_1966546_8 receptor - - - 0.0002138 50.0
SHD3_k127_1986962_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.557e-249 797.0
SHD3_k127_1986962_1 Heat shock 70 kDa protein K04043 - - 6.741e-235 741.0
SHD3_k127_1986962_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000005452 121.0
SHD3_k127_1986962_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000001197 106.0
SHD3_k127_1986962_12 Rossmann-like domain - - - 0.00000000000000001927 93.0
SHD3_k127_1986962_13 Mitochondrial biogenesis AIM24 - - - 0.000000000000002892 90.0
SHD3_k127_1986962_14 Modulates RecA activity K03565 - - 0.00000008862 60.0
SHD3_k127_1986962_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 533.0
SHD3_k127_1986962_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 419.0
SHD3_k127_1986962_4 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 355.0
SHD3_k127_1986962_5 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003927 274.0
SHD3_k127_1986962_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000005631 229.0
SHD3_k127_1986962_7 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II - - - 0.0000000000000000000000000000000000000000000000000000000007644 213.0
SHD3_k127_1986962_8 Transglycosylase SLT domain - - - 0.000000000000000000000000000000008038 137.0
SHD3_k127_1986962_9 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000001704 123.0
SHD3_k127_1992551_0 Sulfate permease family - - - 1.28e-224 709.0
SHD3_k127_1992551_1 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 468.0
SHD3_k127_1992551_10 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000007517 220.0
SHD3_k127_1992551_11 Fusaric acid resistance protein-like - - - 0.0000000000000000000000000000000000000000000003195 185.0
SHD3_k127_1992551_12 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000000000000002293 167.0
SHD3_k127_1992551_13 - - - - 0.000000000000000000000000000000000000000000226 174.0
SHD3_k127_1992551_14 - - - - 0.0000000000000000000000000000001213 128.0
SHD3_k127_1992551_15 Ion channel - - - 0.0003293 49.0
SHD3_k127_1992551_2 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 474.0
SHD3_k127_1992551_3 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 426.0
SHD3_k127_1992551_4 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 415.0
SHD3_k127_1992551_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 380.0
SHD3_k127_1992551_6 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 346.0
SHD3_k127_1992551_7 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 324.0
SHD3_k127_1992551_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001439 273.0
SHD3_k127_1992551_9 Aldose 1-epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000001516 237.0
SHD3_k127_2024368_0 Carboxypeptidase regulatory-like domain - - - 5.188e-197 661.0
SHD3_k127_2024368_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 522.0
SHD3_k127_2024368_10 Pfam Methyltransferase - - - 0.0000000000000000000000000000000000000000001884 166.0
SHD3_k127_2024368_11 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000009758 173.0
SHD3_k127_2024368_12 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000001197 115.0
SHD3_k127_2024368_13 Bacterial membrane protein YfhO - - - 0.000000000000000000002478 110.0
SHD3_k127_2024368_14 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000007167 86.0
SHD3_k127_2024368_15 Uncharacterised protein family (UPF0158) - - - 0.00000005056 62.0
SHD3_k127_2024368_2 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 493.0
SHD3_k127_2024368_3 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 458.0
SHD3_k127_2024368_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 361.0
SHD3_k127_2024368_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 323.0
SHD3_k127_2024368_6 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002523 295.0
SHD3_k127_2024368_7 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005265 278.0
SHD3_k127_2024368_8 Phenylacetate-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000000001645 232.0
SHD3_k127_2024368_9 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000002236 234.0
SHD3_k127_2042451_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 7.217e-212 686.0
SHD3_k127_2042451_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.553e-200 632.0
SHD3_k127_2042451_10 - K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000003421 248.0
SHD3_k127_2042451_11 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000008491 259.0
SHD3_k127_2042451_12 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000004418 235.0
SHD3_k127_2042451_13 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000005469 246.0
SHD3_k127_2042451_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000004331 240.0
SHD3_k127_2042451_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000004387 239.0
SHD3_k127_2042451_16 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000000000000000004553 223.0
SHD3_k127_2042451_17 - - - - 0.000000000000000000000000000000000000000000000000000000001749 213.0
SHD3_k127_2042451_18 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000003331 220.0
SHD3_k127_2042451_19 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.000000000000000000000000000000000000000000004374 173.0
SHD3_k127_2042451_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008627 609.0
SHD3_k127_2042451_20 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000001182 174.0
SHD3_k127_2042451_21 DNA-templated transcription, initiation K03088,K07263 - - 0.000000000000000000000000000000001074 138.0
SHD3_k127_2042451_23 GIY-YIG catalytic domain - - - 0.00000000000000000000000001576 112.0
SHD3_k127_2042451_24 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.000000034 65.0
SHD3_k127_2042451_3 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 605.0
SHD3_k127_2042451_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 374.0
SHD3_k127_2042451_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 332.0
SHD3_k127_2042451_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 341.0
SHD3_k127_2042451_7 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 310.0
SHD3_k127_2042451_8 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 304.0
SHD3_k127_2042451_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008203 250.0
SHD3_k127_2067907_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K21624 - 4.2.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 550.0
SHD3_k127_2067907_1 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 368.0
SHD3_k127_2067907_10 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000002441 183.0
SHD3_k127_2067907_11 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.00000000000000000000000000000000007921 150.0
SHD3_k127_2067907_12 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000001885 145.0
SHD3_k127_2067907_13 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000195 136.0
SHD3_k127_2067907_14 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.000000000000000000000000005523 128.0
SHD3_k127_2067907_15 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000000001666 82.0
SHD3_k127_2067907_16 antisigma factor binding - - - 0.00000000002502 71.0
SHD3_k127_2067907_17 Histidine kinase-like ATPase domain - - - 0.000000004935 59.0
SHD3_k127_2067907_18 protein conserved in bacteria K09924 - - 0.000003854 55.0
SHD3_k127_2067907_19 E-Z type HEAT repeats - - - 0.0001573 55.0
SHD3_k127_2067907_2 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 368.0
SHD3_k127_2067907_3 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 359.0
SHD3_k127_2067907_4 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 311.0
SHD3_k127_2067907_5 PFAM ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 321.0
SHD3_k127_2067907_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 298.0
SHD3_k127_2067907_7 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000003483 251.0
SHD3_k127_2067907_8 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000001027 238.0
SHD3_k127_2067907_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000003598 199.0
SHD3_k127_2119518_0 Bacterial protein of unknown function (DUF885) - - - 2.035e-210 669.0
SHD3_k127_2119518_1 PFAM Aldehyde dehydrogenase K13877 - 1.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 572.0
SHD3_k127_2119518_10 - - - - 0.0000009579 59.0
SHD3_k127_2119518_2 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 389.0
SHD3_k127_2119518_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 386.0
SHD3_k127_2119518_4 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 376.0
SHD3_k127_2119518_5 Belongs to the DapA family K21062 - 3.5.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 350.0
SHD3_k127_2119518_6 4-hydroxyproline epimerase activity K01777,K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.4,5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 327.0
SHD3_k127_2119518_7 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 327.0
SHD3_k127_2119518_8 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001091 256.0
SHD3_k127_2119518_9 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000124 88.0
SHD3_k127_2174559_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.483e-267 854.0
SHD3_k127_2174559_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.525e-230 736.0
SHD3_k127_2174559_10 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000453 201.0
SHD3_k127_2174559_11 L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000002045 201.0
SHD3_k127_2174559_12 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.00000000000000000000000000000000000000000000000000215 203.0
SHD3_k127_2174559_13 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000002362 177.0
SHD3_k127_2174559_14 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000001588 186.0
SHD3_k127_2174559_15 Transmembrane and TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000004494 175.0
SHD3_k127_2174559_16 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000001464 151.0
SHD3_k127_2174559_17 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000007804 105.0
SHD3_k127_2174559_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000002413 88.0
SHD3_k127_2174559_19 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000001612 84.0
SHD3_k127_2174559_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 359.0
SHD3_k127_2174559_20 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000001843 89.0
SHD3_k127_2174559_21 - - - - 0.00000000000000246 81.0
SHD3_k127_2174559_22 SNARE associated Golgi protein - - - 0.000000000003094 68.0
SHD3_k127_2174559_23 Polyprenyl synthetase K05355 GO:0000010,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009108,GO:0009987,GO:0010142,GO:0016020,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032476,GO:0032991,GO:0042180,GO:0042181,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045337,GO:0045338,GO:0051186,GO:0051188,GO:0071704,GO:0090407,GO:1901576,GO:1901661,GO:1901663,GO:1902494,GO:1902767,GO:1990234 2.5.1.82,2.5.1.83 0.000006674 50.0
SHD3_k127_2174559_3 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 305.0
SHD3_k127_2174559_4 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 287.0
SHD3_k127_2174559_5 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001019 307.0
SHD3_k127_2174559_6 Bacterial regulatory protein, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004956 291.0
SHD3_k127_2174559_7 L-serine dehydratase, iron-sulfur-dependent, alpha subunit K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000008306 244.0
SHD3_k127_2174559_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000002002 241.0
SHD3_k127_2174559_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000005731 223.0
SHD3_k127_2178533_0 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 427.0
SHD3_k127_2178533_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 351.0
SHD3_k127_2178533_10 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000004204 230.0
SHD3_k127_2178533_11 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000002905 164.0
SHD3_k127_2178533_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000313 135.0
SHD3_k127_2178533_13 Belongs to the UPF0312 family - - - 0.0000000000000000000001423 114.0
SHD3_k127_2178533_2 Peptidase family M1 domain K01256,K08776 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 361.0
SHD3_k127_2178533_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 336.0
SHD3_k127_2178533_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 313.0
SHD3_k127_2178533_5 ABC transporter permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001504 286.0
SHD3_k127_2178533_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002316 271.0
SHD3_k127_2178533_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002648 278.0
SHD3_k127_2178533_8 Allophanate hydrolase subunit 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000103 292.0
SHD3_k127_2178533_9 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000331 257.0
SHD3_k127_2183422_0 Protein kinase domain K12132 - 2.7.11.1 2.312e-227 755.0
SHD3_k127_2183422_1 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 530.0
SHD3_k127_2183422_11 DinB family - - - 0.000003 59.0
SHD3_k127_2183422_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 311.0
SHD3_k127_2183422_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000584 224.0
SHD3_k127_2183422_4 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000011 228.0
SHD3_k127_2183422_5 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000002735 228.0
SHD3_k127_2183422_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000006522 207.0
SHD3_k127_2183422_7 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000954 147.0
SHD3_k127_2183422_8 response regulator K07684 - - 0.000000000004861 68.0
SHD3_k127_2183422_9 Domain of unknown function (DUF4136) - - - 0.000000006834 68.0
SHD3_k127_2215602_0 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 557.0
SHD3_k127_2215602_1 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 474.0
SHD3_k127_2215602_2 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000421 306.0
SHD3_k127_2215602_3 - - - - 0.0000000000000000000000000000000000000000000000000001837 197.0
SHD3_k127_2215602_4 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000005547 137.0
SHD3_k127_2215602_5 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000007099 122.0
SHD3_k127_2215602_6 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000282 98.0
SHD3_k127_2228697_0 ErfK YbiS YcfS YnhG family protein K21470 - - 1.572e-208 671.0
SHD3_k127_2228697_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006792 298.0
SHD3_k127_2228697_11 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.000001529 50.0
SHD3_k127_2228697_2 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000006079 226.0
SHD3_k127_2228697_3 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000002732 226.0
SHD3_k127_2228697_4 - - - - 0.000000000000000000000000000000000000000000000000000004223 214.0
SHD3_k127_2228697_5 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000001667 151.0
SHD3_k127_2228697_6 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000001907 130.0
SHD3_k127_2228697_7 Sulfatase - - - 0.0000000000000000000000000000001085 144.0
SHD3_k127_2228697_8 PQQ enzyme repeat - - - 0.00000000000000000000008564 115.0
SHD3_k127_2228697_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000003012 80.0
SHD3_k127_2235606_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000001271 204.0
SHD3_k127_2235606_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000001062 217.0
SHD3_k127_2235606_2 Sigma-54 interaction domain K02584,K07713,K15836,K21009 - - 0.0000000000000000000000000000000000000000000005759 185.0
SHD3_k127_2235606_3 Protein tyrosine kinase - - - 0.0000000000000000000000000000001661 139.0
SHD3_k127_2244666_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 584.0
SHD3_k127_2244666_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 501.0
SHD3_k127_2244666_10 Protein of unknown function (DUF3738) - - - 0.00000000000000000004788 102.0
SHD3_k127_2244666_11 efflux transmembrane transporter activity - - - 0.0000000000000000123 87.0
SHD3_k127_2244666_13 lactoylglutathione lyase activity - - - 0.000000000004641 72.0
SHD3_k127_2244666_14 Chlorophyllase - - - 0.000000000009018 71.0
SHD3_k127_2244666_15 membrane - - - 0.0001339 55.0
SHD3_k127_2244666_16 Serine aminopeptidase, S33 - - - 0.0006974 53.0
SHD3_k127_2244666_2 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 396.0
SHD3_k127_2244666_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 304.0
SHD3_k127_2244666_4 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003718 289.0
SHD3_k127_2244666_5 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000005626 228.0
SHD3_k127_2244666_6 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000005865 154.0
SHD3_k127_2244666_7 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000003911 170.0
SHD3_k127_2244666_8 negative regulation of transcription, DNA-templated K10947 - - 0.000000000000000000000000000000000003709 140.0
SHD3_k127_2244666_9 Penicillinase repressor - - - 0.0000000000000000000000000000001114 128.0
SHD3_k127_2291040_0 Voltage gated chloride channel - - - 2.171e-214 685.0
SHD3_k127_2291040_1 Serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 505.0
SHD3_k127_2291040_2 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 475.0
SHD3_k127_2291040_3 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 407.0
SHD3_k127_2291040_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 343.0
SHD3_k127_2291040_5 Glycosyltransferase, group 1 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004075 274.0
SHD3_k127_2291040_6 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000002567 208.0
SHD3_k127_2291040_7 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000002158 195.0
SHD3_k127_2291040_8 GTP cyclohydrolase 1 K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000001891 196.0
SHD3_k127_2291040_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000002947 138.0
SHD3_k127_2303251_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 465.0
SHD3_k127_2303251_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 308.0
SHD3_k127_2303251_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000009149 226.0
SHD3_k127_2303251_3 SMART phosphoesterase PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000147 169.0
SHD3_k127_2303251_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000003873 57.0
SHD3_k127_2326101_0 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003909 252.0
SHD3_k127_2326101_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000001652 226.0
SHD3_k127_2326101_2 endo-1,4-beta-xylanase activity - GO:0005575,GO:0005576 - 0.00000000005158 71.0
SHD3_k127_2330274_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.0 1304.0
SHD3_k127_2330274_1 Beta-lactamase - - - 2.903e-277 876.0
SHD3_k127_2330274_2 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 370.0
SHD3_k127_2330274_3 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000000007641 209.0
SHD3_k127_2330274_4 MafB19-like deaminase - - - 0.00000000000000000001532 98.0
SHD3_k127_2330274_5 YjbR - - - 0.00000000000000000007381 94.0
SHD3_k127_2379534_0 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 582.0
SHD3_k127_2379534_1 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 524.0
SHD3_k127_2379534_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 450.0
SHD3_k127_2379534_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006275 300.0
SHD3_k127_2392219_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 482.0
SHD3_k127_2392219_1 Bifunctional purine biosynthesis protein PurH K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 495.0
SHD3_k127_2392219_2 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000002546 225.0
SHD3_k127_2392219_3 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000002975 200.0
SHD3_k127_2392219_4 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000009652 181.0
SHD3_k127_2392219_6 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000003207 104.0
SHD3_k127_2392219_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000007903 65.0
SHD3_k127_2404739_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 575.0
SHD3_k127_2404739_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 373.0
SHD3_k127_2404739_2 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 317.0
SHD3_k127_2404739_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000001494 86.0
SHD3_k127_2428784_0 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 620.0
SHD3_k127_2428784_1 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000002281 235.0
SHD3_k127_2428784_2 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000009447 206.0
SHD3_k127_2428784_3 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000004085 174.0
SHD3_k127_2428784_4 ECF sigma factor - - - 0.000000000000000000000000000000000000003349 156.0
SHD3_k127_2428784_5 Pkd domain containing protein - - - 0.000001405 60.0
SHD3_k127_2444281_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 522.0
SHD3_k127_2444281_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 439.0
SHD3_k127_2444281_10 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 294.0
SHD3_k127_2444281_11 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001988 282.0
SHD3_k127_2444281_12 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000007859 243.0
SHD3_k127_2444281_13 Permease YjgP YjgQ family protein K07091,K11720 - - 0.0000000000000000000000000000000000000000000000000000000002083 224.0
SHD3_k127_2444281_14 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000008706 208.0
SHD3_k127_2444281_15 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000004121 206.0
SHD3_k127_2444281_16 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000001364 196.0
SHD3_k127_2444281_17 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000002 191.0
SHD3_k127_2444281_18 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000009631 157.0
SHD3_k127_2444281_19 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000002113 142.0
SHD3_k127_2444281_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 391.0
SHD3_k127_2444281_20 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.00000000000000000000000000835 119.0
SHD3_k127_2444281_21 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.000000000000000000000004216 111.0
SHD3_k127_2444281_22 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.000000000000000000001118 107.0
SHD3_k127_2444281_23 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000003389 103.0
SHD3_k127_2444281_24 lipopolysaccharide transport K09774 - - 0.0000000001826 75.0
SHD3_k127_2444281_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 366.0
SHD3_k127_2444281_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 360.0
SHD3_k127_2444281_5 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 353.0
SHD3_k127_2444281_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 317.0
SHD3_k127_2444281_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 321.0
SHD3_k127_2444281_8 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 328.0
SHD3_k127_2444281_9 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 305.0
SHD3_k127_2449012_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 359.0
SHD3_k127_2449012_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 329.0
SHD3_k127_2449012_2 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000005084 265.0
SHD3_k127_2449012_3 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000006783 232.0
SHD3_k127_2449012_4 photosynthesis - - - 0.0000000000000000000000000000000000000001075 164.0
SHD3_k127_2449012_6 PFAM blue (type 1) copper domain protein - - - 0.0000003499 57.0
SHD3_k127_2503118_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.124e-250 811.0
SHD3_k127_2503118_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000003094 81.0
SHD3_k127_2503118_2 - - - - 0.0000006321 57.0
SHD3_k127_2525937_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 497.0
SHD3_k127_2525937_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 484.0
SHD3_k127_2525937_2 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 293.0
SHD3_k127_2525937_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001082 283.0
SHD3_k127_2525937_4 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000004347 220.0
SHD3_k127_2525937_5 Glutathione peroxidase - - - 0.0000000000000000000000001271 114.0
SHD3_k127_2583050_0 MacB-like periplasmic core domain - - - 3.824e-241 775.0
SHD3_k127_2583050_1 Prolyl oligopeptidase K01322 - 3.4.21.26 3.189e-235 747.0
SHD3_k127_2583050_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000002461 152.0
SHD3_k127_2583050_12 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000001617 137.0
SHD3_k127_2583050_13 DinB superfamily - - - 0.000000000000000000000000000001328 136.0
SHD3_k127_2583050_14 Dienelactone hydrolase family - - - 0.0000000000000000000000002929 116.0
SHD3_k127_2583050_15 - - - - 0.00000000000000000000004508 110.0
SHD3_k127_2583050_16 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000001913 103.0
SHD3_k127_2583050_19 collagen metabolic process - - - 0.00000000001294 74.0
SHD3_k127_2583050_2 Sodium/hydrogen exchanger family K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 513.0
SHD3_k127_2583050_20 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000036 69.0
SHD3_k127_2583050_21 Domain of unknown function (DUF4440) - - - 0.00000001821 61.0
SHD3_k127_2583050_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 400.0
SHD3_k127_2583050_4 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 344.0
SHD3_k127_2583050_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 323.0
SHD3_k127_2583050_6 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000004381 214.0
SHD3_k127_2583050_7 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000006014 203.0
SHD3_k127_2583050_8 PFAM thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000000000001158 166.0
SHD3_k127_2583050_9 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000002659 157.0
SHD3_k127_2598891_0 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 3.922e-222 724.0
SHD3_k127_2598891_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 582.0
SHD3_k127_2598891_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 365.0
SHD3_k127_2598891_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 310.0
SHD3_k127_2598891_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001664 276.0
SHD3_k127_2598891_5 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000005275 266.0
SHD3_k127_2608057_0 PFAM aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 351.0
SHD3_k127_2608057_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 355.0
SHD3_k127_2608057_2 Peptidase family S51 K13282 - 3.4.15.6 0.0000000000000000000000000000000000000000000000000000000000000006341 234.0
SHD3_k127_2608057_3 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000004899 218.0
SHD3_k127_2608057_4 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000007289 124.0
SHD3_k127_2608057_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000004454 130.0
SHD3_k127_2608057_6 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000002873 60.0
SHD3_k127_2608057_7 Carboxypeptidase regulatory-like domain - - - 0.0001874 54.0
SHD3_k127_2611054_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 592.0
SHD3_k127_2611054_1 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 456.0
SHD3_k127_2611054_2 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 417.0
SHD3_k127_2611054_3 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 330.0
SHD3_k127_2611054_4 EVE domain - - - 0.0000000000000000000000000000000009613 150.0
SHD3_k127_2611054_5 Protein conserved in bacteria - - - 0.00000000000000000000000002574 113.0
SHD3_k127_2611054_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0001385 46.0
SHD3_k127_2619162_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 385.0
SHD3_k127_2619162_1 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000006788 225.0
SHD3_k127_2619162_2 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000000002673 170.0
SHD3_k127_2619162_3 Belongs to the pseudouridine synthase RsuA family K06178,K06182,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000001254 160.0
SHD3_k127_2619162_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000003233 169.0
SHD3_k127_2619162_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000001607 140.0
SHD3_k127_2619162_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000005929 98.0
SHD3_k127_2619162_7 - - - - 0.000000000002288 81.0
SHD3_k127_2619162_8 HEAT repeats - - - 0.0007872 53.0
SHD3_k127_2660267_0 Succinyl-CoA ligase like flavodoxin domain K09181 - - 2.621e-269 857.0
SHD3_k127_2660267_1 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 445.0
SHD3_k127_2660267_10 DNA-sulfur modification-associated - - - 0.0000005181 61.0
SHD3_k127_2660267_11 Histidine kinase - - - 0.0000008943 55.0
SHD3_k127_2660267_3 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000004781 229.0
SHD3_k127_2660267_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000294 202.0
SHD3_k127_2660267_5 CBS domain K04767 - - 0.00000000000000000000000000000000000000000002992 164.0
SHD3_k127_2660267_6 PFAM EAL domain - - - 0.0000000000000000000000000002293 134.0
SHD3_k127_2660267_7 - - - - 0.0000000000000000001698 91.0
SHD3_k127_2660267_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000002042 98.0
SHD3_k127_2660267_9 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit K04762 - - 0.000000000016 73.0
SHD3_k127_2680691_0 cluster binding protein K18929 - - 3.084e-203 643.0
SHD3_k127_2680691_1 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 329.0
SHD3_k127_2680691_2 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000001734 246.0
SHD3_k127_2680691_3 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000005371 227.0
SHD3_k127_275176_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1140.0
SHD3_k127_275176_1 - - - - 0.00000000000000000000000000000000000000004247 174.0
SHD3_k127_275176_2 Penicillinase repressor - - - 0.000000000000000000000000000000000002409 148.0
SHD3_k127_275176_3 Alternative locus ID - - - 0.00000000001226 78.0
SHD3_k127_275176_4 Putative adhesin - - - 0.000001109 61.0
SHD3_k127_2768378_0 L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 338.0
SHD3_k127_2768378_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000001419 216.0
SHD3_k127_2768378_2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000003139 199.0
SHD3_k127_2768378_3 peptidase - - - 0.0000000000000000000000000000000000000000000000000001666 207.0
SHD3_k127_2768378_4 spore germination - - - 0.000000000000000000000000000000000000000000000000005137 198.0
SHD3_k127_2768378_5 Spore Coat K01790 - 5.1.3.13 0.0000000000000000000000000000004886 129.0
SHD3_k127_2768378_6 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000004681 128.0
SHD3_k127_2768378_7 N-acetyltransferase - - - 0.00000000000000000000001737 116.0
SHD3_k127_2768378_8 PFAM glycosyl transferase family 39 K07264 - 2.4.2.43 0.00000000000002787 87.0
SHD3_k127_2768378_9 SprT homologues. - - - 0.00002329 54.0
SHD3_k127_2793345_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.979e-265 831.0
SHD3_k127_2793345_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 317.0
SHD3_k127_2793345_10 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00003243 50.0
SHD3_k127_2793345_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002159 289.0
SHD3_k127_2793345_3 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001496 276.0
SHD3_k127_2793345_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000003578 198.0
SHD3_k127_2793345_5 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000003504 175.0
SHD3_k127_2793345_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000002637 173.0
SHD3_k127_2793345_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000006683 117.0
SHD3_k127_2793345_8 cell redox homeostasis - - - 0.00000000000000000000001499 108.0
SHD3_k127_2793345_9 TQO small subunit DoxD K16937 - 1.8.5.2 0.00002357 57.0
SHD3_k127_2831982_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 417.0
SHD3_k127_2831982_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002477 267.0
SHD3_k127_2831982_2 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.0000000000000000000000000000000000000000000000000000000314 210.0
SHD3_k127_2831982_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000001267 166.0
SHD3_k127_2831982_4 Peptidase family M23 K21471 - - 0.0000000000000000000000000004509 133.0
SHD3_k127_2831982_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0003368 53.0
SHD3_k127_2883369_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 571.0
SHD3_k127_2883369_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 523.0
SHD3_k127_2883369_10 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000005067 228.0
SHD3_k127_2883369_11 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000001263 165.0
SHD3_k127_2883369_12 low-complexity proteins - - - 0.0000000000000000000000000000000000000001948 171.0
SHD3_k127_2883369_13 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000001129 158.0
SHD3_k127_2883369_14 Macro domain protein - - - 0.00000000000000000000000000000000000002262 162.0
SHD3_k127_2883369_15 MlaD protein K02067 - - 0.0000000000000000000000000000001786 140.0
SHD3_k127_2883369_16 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000000000000000000003386 116.0
SHD3_k127_2883369_17 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000001299 113.0
SHD3_k127_2883369_18 Domain of unknown function (DUF4340) - - - 0.00000000000000000002814 105.0
SHD3_k127_2883369_19 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.0000000000000000002253 91.0
SHD3_k127_2883369_2 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 496.0
SHD3_k127_2883369_20 ABC-type multidrug transport system ATPase component K01990 - - 0.00006785 48.0
SHD3_k127_2883369_21 Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis K08906 - - 0.0001412 49.0
SHD3_k127_2883369_3 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 411.0
SHD3_k127_2883369_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 366.0
SHD3_k127_2883369_5 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 348.0
SHD3_k127_2883369_6 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 310.0
SHD3_k127_2883369_7 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 280.0
SHD3_k127_2883369_8 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000059 262.0
SHD3_k127_2883369_9 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000131 259.0
SHD3_k127_2897538_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 541.0
SHD3_k127_2897538_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 422.0
SHD3_k127_2897538_2 Transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 368.0
SHD3_k127_2897538_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 341.0
SHD3_k127_2897538_4 Imidazolonepropionase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 299.0
SHD3_k127_2897538_5 Glyoxalase-like domain - - - 0.00000000000000000000000000003076 123.0
SHD3_k127_2897538_6 PFAM Diacylglycerol kinase, catalytic - - - 0.000000000001839 75.0
SHD3_k127_2898931_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 395.0
SHD3_k127_2898931_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000006639 170.0
SHD3_k127_2898931_2 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000661 85.0
SHD3_k127_2898931_3 Transmembrane secretion effector K08225 - - 0.000000000000001057 79.0
SHD3_k127_2898931_4 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.0000000000006192 74.0
SHD3_k127_294208_0 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 411.0
SHD3_k127_294208_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 315.0
SHD3_k127_294208_10 YigZ family - - - 0.000000000000000000002467 106.0
SHD3_k127_294208_11 Peptidase family M1 domain - - - 0.000000000000002044 91.0
SHD3_k127_294208_2 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001219 273.0
SHD3_k127_294208_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002106 274.0
SHD3_k127_294208_4 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000008046 244.0
SHD3_k127_294208_5 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000002894 229.0
SHD3_k127_294208_6 PFAM glycosyl transferase family 39 K07264 - 2.4.2.43 0.00000000000000000000000000000000000000000000000000000000000005507 238.0
SHD3_k127_294208_7 SAM-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000009171 178.0
SHD3_k127_294208_8 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.0000000000000000000000000000000003572 154.0
SHD3_k127_294208_9 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000009883 137.0
SHD3_k127_299733_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1234.0
SHD3_k127_299733_1 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 3.832e-283 920.0
SHD3_k127_299733_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 405.0
SHD3_k127_299733_3 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 377.0
SHD3_k127_299733_4 methyltransferase activity - - - 0.000000000000000000005391 106.0
SHD3_k127_3059239_0 OPT oligopeptide transporter protein - - - 4.262e-296 923.0
SHD3_k127_3059239_1 metalloendopeptidase activity K01283 - 3.4.15.1 8.625e-253 792.0
SHD3_k127_3059239_10 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 310.0
SHD3_k127_3059239_11 Alanine racemase K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 296.0
SHD3_k127_3059239_12 PFAM ribonuclease II K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000002428 235.0
SHD3_k127_3059239_13 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000007614 188.0
SHD3_k127_3059239_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000005734 181.0
SHD3_k127_3059239_15 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000004642 173.0
SHD3_k127_3059239_16 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000007571 179.0
SHD3_k127_3059239_17 - - - - 0.0000000000000000000000000000000000001541 148.0
SHD3_k127_3059239_18 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000007598 150.0
SHD3_k127_3059239_19 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000001001 139.0
SHD3_k127_3059239_2 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 3.349e-195 623.0
SHD3_k127_3059239_20 Helix-turn-helix domain - - - 0.000000000000000000000000000003726 127.0
SHD3_k127_3059239_21 - - - - 0.000000000000000000000000001137 120.0
SHD3_k127_3059239_22 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.0000000000000000000006175 111.0
SHD3_k127_3059239_23 Phosphoglycerate mutase family - - - 0.000000000000000000004087 99.0
SHD3_k127_3059239_24 DoxX K15977 - - 0.000000000000001337 85.0
SHD3_k127_3059239_25 - - - - 0.00000001951 65.0
SHD3_k127_3059239_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 557.0
SHD3_k127_3059239_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 500.0
SHD3_k127_3059239_5 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 466.0
SHD3_k127_3059239_6 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 386.0
SHD3_k127_3059239_7 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 379.0
SHD3_k127_3059239_8 RNB K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 379.0
SHD3_k127_3059239_9 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 317.0
SHD3_k127_3063040_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 385.0
SHD3_k127_3063040_1 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000009175 244.0
SHD3_k127_3063040_10 phosphorelay signal transduction system - - - 0.0008195 42.0
SHD3_k127_3063040_2 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000204 222.0
SHD3_k127_3063040_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000004522 188.0
SHD3_k127_3063040_4 Histidine kinase K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000001013 186.0
SHD3_k127_3063040_5 gamma-glutamyl-gamma-aminobutyrate hydrolase activity K07010 - - 0.0000000000000000000000000000000000001443 161.0
SHD3_k127_3063040_6 Tellurite resistance protein TerB - - - 0.00000000000000003757 87.0
SHD3_k127_3063040_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000005595 95.0
SHD3_k127_3063040_8 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000003179 89.0
SHD3_k127_3063040_9 DinB superfamily - - - 0.000000000001334 74.0
SHD3_k127_3074488_0 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 517.0
SHD3_k127_3074488_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 430.0
SHD3_k127_3074488_2 Involved in the processing of the 5'end of 16S rRNA K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 398.0
SHD3_k127_3074488_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001296 281.0
SHD3_k127_3074488_4 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000011 100.0
SHD3_k127_3074488_5 PFAM FecR protein - - - 0.0000000000000000003664 101.0
SHD3_k127_3074488_6 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0001221 50.0
SHD3_k127_3080499_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 7.195e-246 778.0
SHD3_k127_3080499_1 PFAM Leukotriene A4 hydrolase, C-terminal - - - 1.942e-210 670.0
SHD3_k127_3080499_2 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 481.0
SHD3_k127_3080499_3 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 482.0
SHD3_k127_3080499_4 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000007578 233.0
SHD3_k127_3080499_5 VIT family - - - 0.00000000000000000000000000000000000000000003231 163.0
SHD3_k127_3080499_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000001355 155.0
SHD3_k127_3080499_7 receptor K02014 - - 0.000000000000000000000004094 119.0
SHD3_k127_3096515_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.912e-265 831.0
SHD3_k127_3096515_1 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 504.0
SHD3_k127_3096515_11 Domain of unknown function (DUF4126) - - - 0.00000000000006192 84.0
SHD3_k127_3096515_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 482.0
SHD3_k127_3096515_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 387.0
SHD3_k127_3096515_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000002787 170.0
SHD3_k127_3096515_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000002413 171.0
SHD3_k127_3096515_6 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000008188 140.0
SHD3_k127_3096515_7 Ribosomal protein S18 K02963 - - 0.00000000000000000000004905 107.0
SHD3_k127_3096515_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000001088 88.0
SHD3_k127_3096515_9 heat shock protein binding - - - 0.0000000000000000225 96.0
SHD3_k127_315168_0 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 306.0
SHD3_k127_315168_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 282.0
SHD3_k127_315168_2 PFAM phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002315 246.0
SHD3_k127_315168_3 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002314 244.0
SHD3_k127_315168_4 - - - - 0.000000000000000000000000000000000000000000000000000001246 206.0
SHD3_k127_315168_5 - - - - 0.000000000000000000000000000000000000008316 151.0
SHD3_k127_315168_6 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000007322 131.0
SHD3_k127_315168_7 - - - - 0.0000000427 66.0
SHD3_k127_3224486_0 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 567.0
SHD3_k127_3224486_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 359.0
SHD3_k127_3224486_10 membrane K08988 - - 0.000000001274 60.0
SHD3_k127_3224486_2 response regulator receiver K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003521 249.0
SHD3_k127_3224486_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000001611 231.0
SHD3_k127_3224486_4 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000007449 135.0
SHD3_k127_3224486_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000004801 149.0
SHD3_k127_3224486_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000004521 109.0
SHD3_k127_3224486_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000001286 103.0
SHD3_k127_3224486_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000003947 87.0
SHD3_k127_3224486_9 DNA polymerase III, delta' K02340 - 2.7.7.7 0.0000000000006615 81.0
SHD3_k127_3247245_0 Amidohydrolase family - - - 6.388e-224 741.0
SHD3_k127_3247245_1 methionyl-tRNA aminoacylation K01874,K01890,K06878 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 575.0
SHD3_k127_3247245_10 CAAX protease self-immunity - - - 0.000000000000000005932 89.0
SHD3_k127_3247245_11 protein conserved in archaea - - - 0.00000000000000001607 95.0
SHD3_k127_3247245_12 Protein of unknown function (DUF2905) - - - 0.0000000000000001149 87.0
SHD3_k127_3247245_13 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000003866 63.0
SHD3_k127_3247245_14 Bacterial antitoxin of type II TA system, VapB - - - 0.00008544 47.0
SHD3_k127_3247245_15 metal-dependent membrane protease K07052 - - 0.0001147 53.0
SHD3_k127_3247245_16 Deoxyribonuclease K03424 - - 0.0008316 44.0
SHD3_k127_3247245_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 401.0
SHD3_k127_3247245_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 337.0
SHD3_k127_3247245_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 323.0
SHD3_k127_3247245_5 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000002355 185.0
SHD3_k127_3247245_6 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000006352 184.0
SHD3_k127_3247245_7 STAS domain K04749 - - 0.0000000000000000000000000000000007155 134.0
SHD3_k127_3247245_8 - - - - 0.0000000000000000000000000007086 124.0
SHD3_k127_3247245_9 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000113 114.0
SHD3_k127_3270734_0 4Fe-4S single cluster domain K06937 - - 1.477e-251 791.0
SHD3_k127_3270734_1 GTP-binding protein TypA K06207 - - 2.97e-204 652.0
SHD3_k127_3270734_10 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000003854 266.0
SHD3_k127_3270734_11 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000004181 267.0
SHD3_k127_3270734_12 PFAM Cation efflux - - - 0.0000000000000000000000000000000000000000000000000000000000000000001347 239.0
SHD3_k127_3270734_13 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000003853 227.0
SHD3_k127_3270734_14 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000006801 231.0
SHD3_k127_3270734_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000003656 211.0
SHD3_k127_3270734_16 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000008129 160.0
SHD3_k127_3270734_17 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000003691 150.0
SHD3_k127_3270734_18 - - - - 0.00000000000000000000000000000000006576 141.0
SHD3_k127_3270734_19 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000005476 136.0
SHD3_k127_3270734_2 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 7.8e-198 647.0
SHD3_k127_3270734_20 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.0000000000000000000000000000003597 137.0
SHD3_k127_3270734_21 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000713 139.0
SHD3_k127_3270734_22 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000002012 127.0
SHD3_k127_3270734_23 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000002838 117.0
SHD3_k127_3270734_24 cation transporter - - - 0.00000000000000000004943 105.0
SHD3_k127_3270734_25 Translation initiation factor SUI1 K03113 - - 0.0000000000000000004905 96.0
SHD3_k127_3270734_26 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000006927 87.0
SHD3_k127_3270734_27 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000003094 68.0
SHD3_k127_3270734_28 alginic acid biosynthetic process K09815,K15727,K20276 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000001077 73.0
SHD3_k127_3270734_29 LysM domain - - - 0.00000003897 64.0
SHD3_k127_3270734_3 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 598.0
SHD3_k127_3270734_30 PFAM helix-turn-helix, Fis-type - - - 0.000006916 54.0
SHD3_k127_3270734_31 Bacterial membrane protein YfhO - - - 0.000009431 59.0
SHD3_k127_3270734_4 helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 402.0
SHD3_k127_3270734_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 406.0
SHD3_k127_3270734_6 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 340.0
SHD3_k127_3270734_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 312.0
SHD3_k127_3270734_8 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008413 288.0
SHD3_k127_3270734_9 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002787 278.0
SHD3_k127_3303014_0 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 360.0
SHD3_k127_3303014_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 319.0
SHD3_k127_3303014_2 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009198 306.0
SHD3_k127_3303014_3 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000008957 255.0
SHD3_k127_3387296_0 B12 binding domain - - - 5.238e-229 717.0
SHD3_k127_3387296_1 IgA Peptidase M64 - - - 3.154e-203 642.0
SHD3_k127_3387296_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 496.0
SHD3_k127_3387296_3 guanyl-nucleotide exchange factor activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001965 295.0
SHD3_k127_3387296_4 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004655 267.0
SHD3_k127_3387296_5 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000000002841 171.0
SHD3_k127_3387296_6 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000001774 167.0
SHD3_k127_3387296_7 Bacterial lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000001529 120.0
SHD3_k127_3387296_8 cell adhesion involved in biofilm formation K13735 - - 0.000005911 58.0
SHD3_k127_3393974_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001546 267.0
SHD3_k127_3393974_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000006757 215.0
SHD3_k127_3393974_2 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.0000000000000000000002237 105.0
SHD3_k127_3450910_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 535.0
SHD3_k127_3450910_1 PFAM NAD dependent epimerase dehydratase family K12454 - 5.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 357.0
SHD3_k127_3450910_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001766 280.0
SHD3_k127_3450910_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000146 239.0
SHD3_k127_3450910_4 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000001047 144.0
SHD3_k127_3450910_5 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000007387 147.0
SHD3_k127_350192_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 7.034e-230 723.0
SHD3_k127_350192_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 646.0
SHD3_k127_350192_10 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000002285 125.0
SHD3_k127_350192_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.00000000000000000000000007263 123.0
SHD3_k127_350192_12 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000002983 93.0
SHD3_k127_350192_13 Thioesterase-like superfamily K07107 - - 0.00000000000000001976 96.0
SHD3_k127_350192_14 cheY-homologous receiver domain K11443 - - 0.0000000000005114 78.0
SHD3_k127_350192_15 response regulator K07714 - - 0.0007134 51.0
SHD3_k127_350192_16 Forkhead associated domain - - - 0.0007134 51.0
SHD3_k127_350192_2 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 520.0
SHD3_k127_350192_3 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 399.0
SHD3_k127_350192_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 347.0
SHD3_k127_350192_5 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 328.0
SHD3_k127_350192_6 deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000002565 228.0
SHD3_k127_350192_7 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000000000001632 192.0
SHD3_k127_350192_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000002618 155.0
SHD3_k127_350192_9 membrane-bound metal-dependent K07038 - - 0.000000000000000000000000000008233 132.0
SHD3_k127_3543781_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1057.0
SHD3_k127_3543781_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 9.887e-208 668.0
SHD3_k127_3543781_10 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.0000000000000000000000000000000000000000000000000000000000000000368 237.0
SHD3_k127_3543781_11 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000001946 243.0
SHD3_k127_3543781_12 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000001917 220.0
SHD3_k127_3543781_13 Inner membrane component domain - - - 0.0000000000000000000000000000000000000000000000000000004397 195.0
SHD3_k127_3543781_14 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000004049 190.0
SHD3_k127_3543781_15 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000009423 184.0
SHD3_k127_3543781_16 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000001694 160.0
SHD3_k127_3543781_17 MgtC family K07507 - - 0.00000000000000000000000000000000000001247 149.0
SHD3_k127_3543781_18 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000006826 147.0
SHD3_k127_3543781_19 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000001185 140.0
SHD3_k127_3543781_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 500.0
SHD3_k127_3543781_20 Methyltransferase domain - - - 0.0000000000000000000000000000002419 132.0
SHD3_k127_3543781_21 - - - - 0.0000000000000000000000000003353 126.0
SHD3_k127_3543781_22 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000001386 110.0
SHD3_k127_3543781_23 TonB-dependent receptor - - - 0.00001703 56.0
SHD3_k127_3543781_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 450.0
SHD3_k127_3543781_4 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 407.0
SHD3_k127_3543781_5 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 369.0
SHD3_k127_3543781_6 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 362.0
SHD3_k127_3543781_7 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 350.0
SHD3_k127_3543781_8 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000001791 244.0
SHD3_k127_3543781_9 dihydrofolate reductase activity K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000006087 233.0
SHD3_k127_3610348_0 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 617.0
SHD3_k127_3610348_1 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008986 258.0
SHD3_k127_3610348_2 response regulator K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000828 226.0
SHD3_k127_3610348_3 Histidine kinase K07644,K18351 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000005631 229.0
SHD3_k127_3610348_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000007408 150.0
SHD3_k127_3610348_5 Thioredoxin-like - - - 0.00000000000000000000001557 109.0
SHD3_k127_3610348_6 ATPase or kinase K06925 - - 0.00000000000000000000003718 104.0
SHD3_k127_3610348_7 DNA primase - - - 0.0003504 44.0
SHD3_k127_3692561_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.878e-235 739.0
SHD3_k127_3692561_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 9.009e-220 698.0
SHD3_k127_3692561_10 Cbs domain K04767 - - 0.0000000000000004326 84.0
SHD3_k127_3692561_11 Sporulation and spore germination - - - 0.00000000000001641 86.0
SHD3_k127_3692561_12 Family of unknown function (DUF5335) - - - 0.00009228 53.0
SHD3_k127_3692561_2 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 539.0
SHD3_k127_3692561_3 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 438.0
SHD3_k127_3692561_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000002213 276.0
SHD3_k127_3692561_5 phosphoribosyltransferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003022 256.0
SHD3_k127_3692561_6 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000943 253.0
SHD3_k127_3692561_7 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000006903 191.0
SHD3_k127_3692561_8 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000001048 133.0
SHD3_k127_3692561_9 IMP dehydrogenase activity - - - 0.0000000000000002314 91.0
SHD3_k127_3737615_0 Dehydrogenase E1 component K11381 - 1.2.4.4 3.674e-318 991.0
SHD3_k127_3737615_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 271.0
SHD3_k127_3737615_10 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000007766 90.0
SHD3_k127_3737615_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000003768 78.0
SHD3_k127_3737615_12 recombinase activity - - - 0.000002823 52.0
SHD3_k127_3737615_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000003138 213.0
SHD3_k127_3737615_3 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000009644 218.0
SHD3_k127_3737615_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000003888 194.0
SHD3_k127_3737615_5 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.00000000000000000000000000000000000001693 164.0
SHD3_k127_3737615_6 PFAM sodium K14445 - - 0.0000000000000000000000000002347 129.0
SHD3_k127_3737615_7 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000002239 120.0
SHD3_k127_3737615_8 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000006881 128.0
SHD3_k127_3737615_9 amine dehydrogenase activity - - - 0.00000000000000000000000001768 127.0
SHD3_k127_3741928_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 516.0
SHD3_k127_3741928_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 490.0
SHD3_k127_3741928_10 Domain of unknown function (DUF4198) - - - 0.00000000000000000000000000000002419 133.0
SHD3_k127_3741928_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 471.0
SHD3_k127_3741928_3 PFAM Na-Ca exchanger integrin-beta4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 411.0
SHD3_k127_3741928_4 Domain of unknown function (DUF4331) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 346.0
SHD3_k127_3741928_5 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 293.0
SHD3_k127_3741928_6 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000005534 255.0
SHD3_k127_3741928_7 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000003164 223.0
SHD3_k127_3741928_8 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000106 177.0
SHD3_k127_3741928_9 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000008028 172.0
SHD3_k127_3773396_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 5.649e-238 758.0
SHD3_k127_3773396_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.451e-205 677.0
SHD3_k127_3773396_10 Protein of unknown function (DUF503) K09764 - - 0.000000000000000216 83.0
SHD3_k127_3773396_11 TonB C terminal K03832 - - 0.00000000231 70.0
SHD3_k127_3773396_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 383.0
SHD3_k127_3773396_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000008596 213.0
SHD3_k127_3773396_4 TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000005331 194.0
SHD3_k127_3773396_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000008519 126.0
SHD3_k127_3773396_6 CoA binding domain K06929 - - 0.00000000000000000000000009086 115.0
SHD3_k127_3773396_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000002181 109.0
SHD3_k127_3773396_8 Zincin-like metallopeptidase - - - 0.0000000000000000000005096 107.0
SHD3_k127_3773396_9 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000866 96.0
SHD3_k127_3810006_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 563.0
SHD3_k127_3810006_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 363.0
SHD3_k127_3810006_10 Autotransporter beta-domain - - - 0.0000003082 65.0
SHD3_k127_3810006_11 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000125 50.0
SHD3_k127_3810006_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000002347 195.0
SHD3_k127_3810006_3 Polymorphic membrane protein Chlamydia - - - 0.00000000000000000000000000000000000000000000000000303 207.0
SHD3_k127_3810006_4 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000002549 188.0
SHD3_k127_3810006_5 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000001806 161.0
SHD3_k127_3810006_6 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000003093 174.0
SHD3_k127_3810006_7 amine dehydrogenase activity - - - 0.0000000000000000000000000001256 136.0
SHD3_k127_3810006_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000006155 79.0
SHD3_k127_3810006_9 Plasmid pRiA4b ORF-3-like protein - - - 0.00000005132 61.0
SHD3_k127_3839947_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1275.0
SHD3_k127_3839947_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 458.0
SHD3_k127_3839947_10 Cytochrome c - - - 0.000000000000000000000000000000009558 133.0
SHD3_k127_3839947_11 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000002178 121.0
SHD3_k127_3839947_12 VIT family - - - 0.0000000000000002846 81.0
SHD3_k127_3839947_13 PFAM Uroporphyrinogen III synthase HEM4 K01719 - 4.2.1.75 0.00000000244 70.0
SHD3_k127_3839947_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 456.0
SHD3_k127_3839947_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 436.0
SHD3_k127_3839947_4 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 346.0
SHD3_k127_3839947_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 326.0
SHD3_k127_3839947_6 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009064 294.0
SHD3_k127_3839947_7 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001074 270.0
SHD3_k127_3839947_8 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002315 261.0
SHD3_k127_3839947_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000002058 252.0
SHD3_k127_3949139_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 8.993e-195 623.0
SHD3_k127_3949139_1 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 532.0
SHD3_k127_3949139_2 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 387.0
SHD3_k127_3949139_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 360.0
SHD3_k127_3949139_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001374 278.0
SHD3_k127_3949139_5 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000002769 232.0
SHD3_k127_3949139_6 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000002312 195.0
SHD3_k127_3949139_7 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000004886 147.0
SHD3_k127_3949139_9 Tetratricopeptide repeat - - - 0.000002359 57.0
SHD3_k127_3966289_0 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 331.0
SHD3_k127_3966289_1 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 318.0
SHD3_k127_3966289_2 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004261 289.0
SHD3_k127_3966289_3 peptide catabolic process K01256 - 3.4.11.2 0.000000000000000000000000000000000000000001357 175.0
SHD3_k127_3966289_4 DinB superfamily K07552 - - 0.0000000000000000000000000000000000001806 150.0
SHD3_k127_3966289_6 Heavy-metal resistance - - - 0.0003749 53.0
SHD3_k127_3967832_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 4.796e-290 900.0
SHD3_k127_3967832_1 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000003203 258.0
SHD3_k127_3967832_2 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000009745 241.0
SHD3_k127_3967832_3 enzyme related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000002198 237.0
SHD3_k127_3967832_4 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000004432 182.0
SHD3_k127_3967832_5 Salt-induced outer membrane protein K07283 - - 0.000000006867 69.0
SHD3_k127_3967832_6 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00004369 55.0
SHD3_k127_4020800_0 belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 410.0
SHD3_k127_4020800_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 399.0
SHD3_k127_4020800_2 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 357.0
SHD3_k127_4020800_3 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 299.0
SHD3_k127_4020800_4 YCII-related domain - - - 0.000000000000000000000000000000005887 146.0
SHD3_k127_4020800_5 E-Z type HEAT repeats - - - 0.0000005065 63.0
SHD3_k127_4030481_0 lipopolysaccharide transport K22110 - - 0.0 1229.0
SHD3_k127_4030481_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 6.781e-242 774.0
SHD3_k127_4030481_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000008294 265.0
SHD3_k127_4030481_11 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000193 211.0
SHD3_k127_4030481_12 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000001662 191.0
SHD3_k127_4030481_13 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067,K06192 - - 0.000000000000000000000000000000000000001057 166.0
SHD3_k127_4030481_14 Ion transport 2 domain protein - - - 0.00000000000000000000000000000001771 147.0
SHD3_k127_4030481_15 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000000004989 97.0
SHD3_k127_4030481_16 Domain of unknown function (DUF4136) - - - 0.0000000000000002263 87.0
SHD3_k127_4030481_17 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00003861 55.0
SHD3_k127_4030481_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 4.113e-219 691.0
SHD3_k127_4030481_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 547.0
SHD3_k127_4030481_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 487.0
SHD3_k127_4030481_5 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 475.0
SHD3_k127_4030481_6 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 330.0
SHD3_k127_4030481_7 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 321.0
SHD3_k127_4030481_8 PFAM ROK family K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006079 294.0
SHD3_k127_4030481_9 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001636 278.0
SHD3_k127_4104505_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 2.817e-195 616.0
SHD3_k127_4104505_1 Major facilitator superfamily K08167 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 583.0
SHD3_k127_4104505_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 441.0
SHD3_k127_4104505_3 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 297.0
SHD3_k127_4104505_4 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000006225 213.0
SHD3_k127_4104505_5 DoxX-like family - - - 0.00000000000000000000000000000000000000009195 154.0
SHD3_k127_4104505_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000004276 137.0
SHD3_k127_4136755_0 Cys/Met metabolism PLP-dependent enzyme K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 457.0
SHD3_k127_4136755_1 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 429.0
SHD3_k127_4136755_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 320.0
SHD3_k127_4136755_3 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 325.0
SHD3_k127_4136755_4 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 304.0
SHD3_k127_4136755_5 NmrA-like family - - - 0.00000000000000000000000000000000000000000000002355 183.0
SHD3_k127_4136755_6 PAP2 superfamily - - - 0.000000000000000000000000000000000000000001299 168.0
SHD3_k127_4136755_7 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000003234 83.0
SHD3_k127_4153089_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.006e-226 713.0
SHD3_k127_4153089_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 501.0
SHD3_k127_4153089_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 469.0
SHD3_k127_4153089_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000002601 207.0
SHD3_k127_4153089_4 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000002335 109.0
SHD3_k127_4153089_5 CoA carboxylase activity K01960,K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1,6.4.1.3,6.4.1.4 0.0000000000000001354 94.0
SHD3_k127_4153089_6 Peptidase M56 - - - 0.000000000000168 82.0
SHD3_k127_4153089_7 Aspartyl protease - - - 0.00005366 57.0
SHD3_k127_4173234_0 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 386.0
SHD3_k127_4173234_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 345.0
SHD3_k127_4173234_2 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001657 282.0
SHD3_k127_4173234_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005874 261.0
SHD3_k127_4173234_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005317 252.0
SHD3_k127_4173234_5 gluconolactonase activity K01053,K04565 - 1.15.1.1,3.1.1.17 0.0000000000000000000000000000000000000000000000000003054 208.0
SHD3_k127_4173234_6 SMART Transcription regulator, AsnC-type K03718,K03719 - - 0.000000000000000000000000000000000000000000000001371 179.0
SHD3_k127_4173234_7 DinB family - - - 0.000000000000000000000000000000000007597 153.0
SHD3_k127_4188358_0 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 503.0
SHD3_k127_4188358_1 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 429.0
SHD3_k127_4188358_2 ABC transporter C-terminal domain K06158 - - 0.0000000000000000000000000000000000000000000000000000001294 202.0
SHD3_k127_4188358_3 PFAM Glycosyl transferase family 2 K14597 - - 0.0000000000000000000000000000000000000000000000002881 199.0
SHD3_k127_4188358_4 iron-sulfur cluster assembly K07400 - - 0.0000000000000000000000000000000000000000000005789 175.0
SHD3_k127_4188358_5 peptidyl-tyrosine sulfation - - - 0.0001402 54.0
SHD3_k127_4204742_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 604.0
SHD3_k127_4204742_1 gluconolactonase activity K01053,K13735 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 568.0
SHD3_k127_4204742_10 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000007681 191.0
SHD3_k127_4204742_11 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.00000000000000000000000000000000000000000000042 177.0
SHD3_k127_4204742_12 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000388 153.0
SHD3_k127_4204742_13 Protein of unknown function (DUF3224) - - - 0.00000000000000000000000000000000000002172 157.0
SHD3_k127_4204742_14 enzyme binding K00567,K07443 - 2.1.1.63 0.000000000000000000000000002636 124.0
SHD3_k127_4204742_15 - - - - 0.0000000000000000003954 95.0
SHD3_k127_4204742_16 DinB family - - - 0.000000000000000001416 93.0
SHD3_k127_4204742_17 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.00000001343 60.0
SHD3_k127_4204742_18 Preprotein translocase subunit SecD - - - 0.0002926 54.0
SHD3_k127_4204742_19 NB-ARC domain - - - 0.0005396 50.0
SHD3_k127_4204742_2 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 392.0
SHD3_k127_4204742_3 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 320.0
SHD3_k127_4204742_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001364 276.0
SHD3_k127_4204742_5 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002457 237.0
SHD3_k127_4204742_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000695 224.0
SHD3_k127_4204742_7 - - - - 0.000000000000000000000000000000000000000000000000000000000026 210.0
SHD3_k127_4204742_8 Alkylated DNA repair protein - - - 0.0000000000000000000000000000000000000000000000000000000001825 216.0
SHD3_k127_4204742_9 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000002444 198.0
SHD3_k127_4292339_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 392.0
SHD3_k127_4292339_1 PFAM sugar transferase K13012 - - 0.00000000000000000000000000000000000000000000000000000000000000000679 242.0
SHD3_k127_4292339_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000006291 130.0
SHD3_k127_4292339_3 O-Antigen ligase - - - 0.000004906 59.0
SHD3_k127_4333523_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 8.412e-288 902.0
SHD3_k127_4333523_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 309.0
SHD3_k127_4333523_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002485 259.0
SHD3_k127_4333523_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000001117 156.0
SHD3_k127_4333523_4 DinB family - - - 0.0000000000000000000000000000000000008131 144.0
SHD3_k127_4333523_5 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000001488 128.0
SHD3_k127_4376414_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 437.0
SHD3_k127_4376414_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 377.0
SHD3_k127_4376414_10 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000004349 188.0
SHD3_k127_4376414_11 fatty acid desaturase - - - 0.0000000000001144 84.0
SHD3_k127_4376414_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008799 289.0
SHD3_k127_4376414_3 Protein of unknown function (DUF1348) K09958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000124 290.0
SHD3_k127_4376414_4 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005903 294.0
SHD3_k127_4376414_5 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000007515 265.0
SHD3_k127_4376414_6 TIGRFAM daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004425 247.0
SHD3_k127_4376414_7 hydroxypyruvate reductase K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000002785 203.0
SHD3_k127_4376414_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000006061 184.0
SHD3_k127_4376414_9 Diacylglycerol kinase catalytic domain (presumed) - - - 0.000000000000000000000000000000000000000000000005528 183.0
SHD3_k127_4431991_0 Heat shock 70 kDa protein K04043 - - 3.867e-305 945.0
SHD3_k127_4431991_1 MazG family K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.0000000000000000000000000000000000000000000000000000002591 215.0
SHD3_k127_4431991_2 PFAM Peptidase S41 K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000002367 201.0
SHD3_k127_4431991_3 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000007774 181.0
SHD3_k127_4431991_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000142 158.0
SHD3_k127_4431991_5 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000003139 123.0
SHD3_k127_4431991_6 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000007026 109.0
SHD3_k127_4431991_7 Domain of unknown function (DUF1844) - - - 0.0000000002904 67.0
SHD3_k127_4431991_8 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000003691 63.0
SHD3_k127_4435616_0 Involved in the tonB-independent uptake of proteins - - - 1.208e-222 718.0
SHD3_k127_4435616_1 Involved in the tonB-independent uptake of proteins - - - 7.136e-201 668.0
SHD3_k127_4435616_2 Involved in the tonB-independent uptake of proteins - - - 2.565e-195 656.0
SHD3_k127_4435616_3 Involved in the tonB-independent uptake of proteins - - - 5.114e-194 643.0
SHD3_k127_4435616_4 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 401.0
SHD3_k127_4435616_5 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 320.0
SHD3_k127_4435616_6 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.00000004913 61.0
SHD3_k127_4443348_0 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 386.0
SHD3_k127_4443348_1 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004254 276.0
SHD3_k127_4443348_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000003861 256.0
SHD3_k127_4443348_3 TonB-dependent Receptor Plug Domain K16092 - - 0.00000000000000000000000000000000000000000000000000000000008132 232.0
SHD3_k127_4443348_4 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000002888 194.0
SHD3_k127_4443348_7 IMG reference gene - - - 0.00000000000004056 84.0
SHD3_k127_4455751_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.339e-194 636.0
SHD3_k127_4455751_1 Elongation factor SelB winged helix 3 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 429.0
SHD3_k127_4455751_10 YqeY-like protein K09117 - - 0.0000000000000000000000000000001377 128.0
SHD3_k127_4455751_11 cyclohydrolase K01746 - 4.3.1.4 0.00000000000000000000000000006463 131.0
SHD3_k127_4455751_12 CYTH K05873 - 4.6.1.1 0.000000000000000000000009182 114.0
SHD3_k127_4455751_13 Probable zinc-ribbon domain - - - 0.0000000000000000000001115 100.0
SHD3_k127_4455751_14 Helix-hairpin-helix motif K02237 - - 0.000000000000221 83.0
SHD3_k127_4455751_15 Heat shock protein - - - 0.000001022 62.0
SHD3_k127_4455751_16 general secretion pathway protein K08084,K08085 - - 0.0001827 53.0
SHD3_k127_4455751_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 372.0
SHD3_k127_4455751_3 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 361.0
SHD3_k127_4455751_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 293.0
SHD3_k127_4455751_5 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007806 299.0
SHD3_k127_4455751_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001299 265.0
SHD3_k127_4455751_7 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000001095 226.0
SHD3_k127_4455751_8 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000003087 148.0
SHD3_k127_4455751_9 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000002976 151.0
SHD3_k127_449929_0 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 576.0
SHD3_k127_449929_1 magnesium chelatase K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 574.0
SHD3_k127_449929_2 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000001451 246.0
SHD3_k127_449929_3 protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000003041 136.0
SHD3_k127_449929_4 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000001565 143.0
SHD3_k127_449929_5 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000001012 113.0
SHD3_k127_449929_6 - - - - 0.00000000000000000000000003865 117.0
SHD3_k127_449929_7 Redoxin - - - 0.00000000000000000000000008019 116.0
SHD3_k127_4503863_0 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009617 422.0
SHD3_k127_4503863_1 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 376.0
SHD3_k127_4503863_10 Outer membrane protein protective antigen OMA87 - - - 0.0001442 51.0
SHD3_k127_4503863_11 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0003476 48.0
SHD3_k127_4503863_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009569 276.0
SHD3_k127_4503863_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000008605 200.0
SHD3_k127_4503863_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000007209 199.0
SHD3_k127_4503863_5 Ku70/Ku80 beta-barrel domain K10979 - - 0.00000000000000000000000000000000000000000001249 172.0
SHD3_k127_4503863_6 hyperosmotic response - - - 0.00000000000000000001311 101.0
SHD3_k127_4503863_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000001993 94.0
SHD3_k127_4503863_8 - - - - 0.000000000000001861 77.0
SHD3_k127_4503863_9 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000002642 58.0
SHD3_k127_4526098_0 Uncharacterized protein family (UPF0051) K09014 - - 6.284e-266 824.0
SHD3_k127_4526098_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 579.0
SHD3_k127_4526098_10 FeS assembly SUF system protein - - - 0.000000000000000000000000000000000000000000000000002595 196.0
SHD3_k127_4526098_11 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000006863 184.0
SHD3_k127_4526098_12 iron ion homeostasis - - - 0.00000000004218 75.0
SHD3_k127_4526098_2 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 502.0
SHD3_k127_4526098_3 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 385.0
SHD3_k127_4526098_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 369.0
SHD3_k127_4526098_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 370.0
SHD3_k127_4526098_6 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 338.0
SHD3_k127_4526098_7 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 299.0
SHD3_k127_4526098_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000001774 226.0
SHD3_k127_4526098_9 TIGRFAM SUF system FeS K04488 - - 0.000000000000000000000000000000000000000000000000000007395 205.0
SHD3_k127_4530229_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.354e-214 689.0
SHD3_k127_4530229_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 343.0
SHD3_k127_4530229_2 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000004462 244.0
SHD3_k127_4530229_3 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000009116 234.0
SHD3_k127_4530229_4 PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000009735 213.0
SHD3_k127_4530229_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000006888 191.0
SHD3_k127_4530229_6 PFAM regulatory protein, MerR K22491 - - 0.0000000000000000000000000000000000000000000000002544 187.0
SHD3_k127_4530229_7 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000001287 110.0
SHD3_k127_4530229_8 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000001433 85.0
SHD3_k127_4542021_0 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 421.0
SHD3_k127_4542021_1 Belongs to the FPG family K05522 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000003234 237.0
SHD3_k127_4542021_2 RF-1 domain - - - 0.00000000000000000001473 100.0
SHD3_k127_4542021_3 sortase family K07284 - 3.4.22.70 0.00006484 54.0
SHD3_k127_4597949_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.294e-272 865.0
SHD3_k127_4597949_1 Polysulphide reductase, NrfD K00185 - - 1.542e-211 670.0
SHD3_k127_4597949_10 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate K01436 - - 0.0000000000000000000000000000000000000000000000000000000000003799 219.0
SHD3_k127_4597949_11 COG1956 GAF domain-containing protein K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000007106 208.0
SHD3_k127_4597949_12 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000001199 213.0
SHD3_k127_4597949_13 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000003507 197.0
SHD3_k127_4597949_14 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000001312 164.0
SHD3_k127_4597949_15 Transglutaminase-like superfamily - - - 0.0000000000000000000000000001904 134.0
SHD3_k127_4597949_16 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000004406 100.0
SHD3_k127_4597949_17 - - - - 0.00000000001109 72.0
SHD3_k127_4597949_19 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000006431 57.0
SHD3_k127_4597949_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 399.0
SHD3_k127_4597949_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 390.0
SHD3_k127_4597949_4 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 305.0
SHD3_k127_4597949_5 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002407 262.0
SHD3_k127_4597949_6 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002629 257.0
SHD3_k127_4597949_7 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001887 254.0
SHD3_k127_4597949_8 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000005305 239.0
SHD3_k127_4597949_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000002811 227.0
SHD3_k127_4668049_0 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 563.0
SHD3_k127_4668049_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 524.0
SHD3_k127_4668049_2 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 356.0
SHD3_k127_4668049_3 transmembrane transporter activity K03296 - - 0.00000000000000000000000000000000000000704 158.0
SHD3_k127_4668049_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000002215 61.0
SHD3_k127_4668049_5 outer membrane efflux protein - - - 0.0005687 52.0
SHD3_k127_4702234_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 428.0
SHD3_k127_4702234_1 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 300.0
SHD3_k127_4702234_2 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000002249 219.0
SHD3_k127_4702234_3 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000001107 140.0
SHD3_k127_4784880_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 477.0
SHD3_k127_4784880_1 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 425.0
SHD3_k127_4784880_10 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000001789 230.0
SHD3_k127_4784880_11 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000001862 217.0
SHD3_k127_4784880_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000001325 196.0
SHD3_k127_4784880_13 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000001751 182.0
SHD3_k127_4784880_14 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000000005643 163.0
SHD3_k127_4784880_15 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000002371 157.0
SHD3_k127_4784880_16 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000002279 158.0
SHD3_k127_4784880_17 Histidine kinase K07315 - 3.1.3.3 0.00000000000000000000000000000000009082 148.0
SHD3_k127_4784880_18 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000000000000003229 132.0
SHD3_k127_4784880_19 Yip1 domain - - - 0.00000000000000000479 94.0
SHD3_k127_4784880_2 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 325.0
SHD3_k127_4784880_20 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000002147 85.0
SHD3_k127_4784880_21 Belongs to the UPF0109 family K06960 - - 0.0000000002389 66.0
SHD3_k127_4784880_22 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000105 52.0
SHD3_k127_4784880_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006438 301.0
SHD3_k127_4784880_4 UDP-glucose 4-epimerase activity K01784,K17947 - 5.1.3.2,5.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000951 291.0
SHD3_k127_4784880_5 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005803 285.0
SHD3_k127_4784880_6 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002602 287.0
SHD3_k127_4784880_7 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000005606 244.0
SHD3_k127_4784880_8 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000001157 241.0
SHD3_k127_4784880_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000002782 245.0
SHD3_k127_482241_0 ATP:ADP antiporter activity K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001268 282.0
SHD3_k127_482241_1 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002954 264.0
SHD3_k127_482241_2 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000005214 220.0
SHD3_k127_482241_3 phosphoprotein phosphatase activity - - - 0.00000000000000000000000000000000000000000000003977 185.0
SHD3_k127_482241_4 - - - - 0.0000000000000000000000000000000000004706 145.0
SHD3_k127_482241_5 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000000000000304 142.0
SHD3_k127_482241_6 - - - - 0.000000000000000000000000000000003182 135.0
SHD3_k127_482241_7 - - - - 0.0000000000000000000000003544 106.0
SHD3_k127_482241_8 Peptidase M48 - - - 0.0000000000000001388 95.0
SHD3_k127_4828848_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 555.0
SHD3_k127_4828848_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 492.0
SHD3_k127_4828848_2 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 371.0
SHD3_k127_4828848_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 342.0
SHD3_k127_4828848_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001269 265.0
SHD3_k127_4828848_5 DNA polymerase III subunit epsilon K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000006023 230.0
SHD3_k127_4828848_6 PFAM Helix-turn-helix, type 11 domain protein K13572 - - 0.0000000000000000000000000000000003665 148.0
SHD3_k127_4828848_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000001049 119.0
SHD3_k127_4828848_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000002236 61.0
SHD3_k127_4863660_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 323.0
SHD3_k127_4863660_1 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 287.0
SHD3_k127_4863660_2 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.00000000000000000000000000000000000000000000000000000000000000009021 249.0
SHD3_k127_4863660_3 of the beta-lactamase K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000008925 188.0
SHD3_k127_4863660_4 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000004932 177.0
SHD3_k127_4863660_5 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000003093 123.0
SHD3_k127_4873021_0 tRNA synthetases class I (K) K01870 - 6.1.1.5 1.269e-290 921.0
SHD3_k127_4873021_1 peptidase K07386 - - 1.022e-248 785.0
SHD3_k127_4873021_10 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000003555 274.0
SHD3_k127_4873021_11 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000001374 248.0
SHD3_k127_4873021_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000001349 215.0
SHD3_k127_4873021_13 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000000005 232.0
SHD3_k127_4873021_14 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000001068 204.0
SHD3_k127_4873021_15 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000001926 186.0
SHD3_k127_4873021_16 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000006751 163.0
SHD3_k127_4873021_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.000000000000000000000000000000000000004266 161.0
SHD3_k127_4873021_18 DNA mismatch repair protein MutT K01515 - 3.6.1.13 0.00000000000000000000000000000000000482 142.0
SHD3_k127_4873021_19 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000000000000000000002231 154.0
SHD3_k127_4873021_2 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.003e-208 667.0
SHD3_k127_4873021_20 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000005681 142.0
SHD3_k127_4873021_21 Glycosyltransferase family 87 - - - 0.00000000000000000000000000000002086 140.0
SHD3_k127_4873021_22 Mechanosensitive ion channel - - - 0.000000000000000000000000000001769 130.0
SHD3_k127_4873021_23 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000003495 115.0
SHD3_k127_4873021_24 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000004211 106.0
SHD3_k127_4873021_25 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000566 96.0
SHD3_k127_4873021_26 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000001405 83.0
SHD3_k127_4873021_27 Putative adhesin - - - 0.00000000000002097 84.0
SHD3_k127_4873021_28 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000004248 79.0
SHD3_k127_4873021_29 outer membrane autotransporter barrel domain protein - - - 0.00000000002317 72.0
SHD3_k127_4873021_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 509.0
SHD3_k127_4873021_30 TIGRFAM TonB family protein K03832 - - 0.00000001521 68.0
SHD3_k127_4873021_31 Glutaredoxin-like domain (DUF836) - - - 0.00000001794 65.0
SHD3_k127_4873021_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 480.0
SHD3_k127_4873021_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 344.0
SHD3_k127_4873021_6 Pfam:Arch_ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004937 290.0
SHD3_k127_4873021_7 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000414 284.0
SHD3_k127_4873021_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000296 284.0
SHD3_k127_4873021_9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000002064 279.0
SHD3_k127_487449_0 Amino acid permease - - - 2.806e-216 693.0
SHD3_k127_487449_1 abc transporter atp-binding protein K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 452.0
SHD3_k127_487449_2 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000049 310.0
SHD3_k127_487449_3 ATP-grasp domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000006439 266.0
SHD3_k127_487449_4 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000002892 280.0
SHD3_k127_487449_5 PFAM Glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000001089 196.0
SHD3_k127_487449_6 iron-sulfur cluster assembly K07400 - - 0.0000000000000000000000000000000000000000000179 169.0
SHD3_k127_487449_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000005221 148.0
SHD3_k127_487449_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000002308 106.0
SHD3_k127_4882531_0 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 432.0
SHD3_k127_4882531_1 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 375.0
SHD3_k127_4882531_2 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 319.0
SHD3_k127_4882531_3 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000001933 194.0
SHD3_k127_4882531_4 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000009354 199.0
SHD3_k127_4882531_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000001682 134.0
SHD3_k127_4882531_6 PFAM NHL repeat containing protein - - - 0.000000000000000000000005395 114.0
SHD3_k127_4882531_8 asparagine synthase K01953 - 6.3.5.4 0.000000000003524 78.0
SHD3_k127_4890652_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 453.0
SHD3_k127_4890652_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 356.0
SHD3_k127_4890652_2 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004425 288.0
SHD3_k127_4890652_3 cellulose binding - - - 0.000000000000000000000000000602 132.0
SHD3_k127_4890652_4 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000003495 125.0
SHD3_k127_4890652_5 Regulatory protein, FmdB - - - 0.000000000000000000001633 98.0
SHD3_k127_4890652_6 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000001996 53.0
SHD3_k127_4946806_0 TLC ATP/ADP transporter K03301 - - 0.000000000000000000000000000000000000000000000000000000000002953 238.0
SHD3_k127_4946806_1 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000002306 195.0
SHD3_k127_4946806_2 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000000000000000000005253 162.0
SHD3_k127_4951618_0 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 459.0
SHD3_k127_4951618_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 450.0
SHD3_k127_4951618_10 RelA SpoT domain protein - - - 0.0000000000000000000000001365 125.0
SHD3_k127_4951618_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000002091 113.0
SHD3_k127_4951618_12 Methyltransferase domain - - - 0.00000000000002097 84.0
SHD3_k127_4951618_2 Ring hydroxylating alpha subunit (catalytic domain) K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 423.0
SHD3_k127_4951618_3 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 386.0
SHD3_k127_4951618_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005212 269.0
SHD3_k127_4951618_5 Metal-dependent phosphohydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008413 245.0
SHD3_k127_4951618_6 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000001018 249.0
SHD3_k127_4951618_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000001636 225.0
SHD3_k127_4951618_8 flavin adenine dinucleotide binding - - - 0.00000000000000000000000000000000000000000000000000000000000008041 231.0
SHD3_k127_4951618_9 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000001488 220.0
SHD3_k127_4957942_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 657.0
SHD3_k127_4957942_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 556.0
SHD3_k127_4957942_2 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 441.0
SHD3_k127_4957942_3 Amino acid permease K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 339.0
SHD3_k127_4957942_4 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 329.0
SHD3_k127_4957942_5 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000001162 188.0
SHD3_k127_4957942_6 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000003896 142.0
SHD3_k127_4957942_7 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000003527 116.0
SHD3_k127_4957942_8 PFAM response regulator receiver K07657,K07658 - - 0.00000000000000000003096 107.0
SHD3_k127_4957942_9 Transcriptional regulator - - - 0.0000000000000002184 92.0
SHD3_k127_498816_0 Large extracellular alpha-helical protein - - - 0.0 1572.0
SHD3_k127_498816_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 4.22e-209 676.0
SHD3_k127_498816_2 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 357.0
SHD3_k127_4991535_0 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 377.0
SHD3_k127_4991535_1 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 325.0
SHD3_k127_4991535_2 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000002543 244.0
SHD3_k127_4991535_3 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000002102 188.0
SHD3_k127_4991535_4 ABC transporter K01990,K19340 - - 0.0000000000000000000000000000000005582 149.0
SHD3_k127_4991535_5 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000002075 84.0
SHD3_k127_4991535_6 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.000000000000002469 89.0
SHD3_k127_4991535_7 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000001634 68.0
SHD3_k127_5005643_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1371.0
SHD3_k127_5005643_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 334.0
SHD3_k127_5005643_2 Transposase K02557,K07484,K13924,K21471 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000002086 262.0
SHD3_k127_5005643_3 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000003035 170.0
SHD3_k127_5005643_4 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000003295 119.0
SHD3_k127_5005643_5 DinB superfamily - - - 0.00000000000000000000001408 110.0
SHD3_k127_5005643_6 non-ribosomal peptide synthetase - - - 0.00001123 56.0
SHD3_k127_5059393_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 400.0
SHD3_k127_5059393_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 364.0
SHD3_k127_5059393_2 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000000000000000000000001539 212.0
SHD3_k127_5059393_3 dienelactone hydrolase - - - 0.000000000000000000000000000000000001504 145.0
SHD3_k127_5059393_4 oxidoreductase activity - - - 0.00001695 57.0
SHD3_k127_5091564_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 578.0
SHD3_k127_5091564_1 TOBE domain K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 332.0
SHD3_k127_5091564_10 - - - - 0.000000000000000000000000000000000000000001449 181.0
SHD3_k127_5091564_11 TOBE domain - - - 0.00000000000000000000000000000004141 129.0
SHD3_k127_5091564_12 Histidine kinase - - - 0.00000000000000000000000000001601 133.0
SHD3_k127_5091564_13 outer membrane efflux protein K12340 - - 0.0000000000000000000000000001047 117.0
SHD3_k127_5091564_14 Iron-sulfur cluster-binding domain - - - 0.00000000000000000008632 103.0
SHD3_k127_5091564_15 Bacterial membrane protein YfhO - - - 0.00000000000000001936 98.0
SHD3_k127_5091564_16 Putative MetA-pathway of phenol degradation - - - 0.000000000002457 78.0
SHD3_k127_5091564_17 - - - - 0.000000008751 68.0
SHD3_k127_5091564_2 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009157 265.0
SHD3_k127_5091564_3 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004311 249.0
SHD3_k127_5091564_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001721 237.0
SHD3_k127_5091564_5 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000003317 222.0
SHD3_k127_5091564_6 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000004238 219.0
SHD3_k127_5091564_7 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000001075 220.0
SHD3_k127_5091564_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000861 211.0
SHD3_k127_5091564_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000007799 171.0
SHD3_k127_5105003_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 470.0
SHD3_k127_5105003_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000004616 216.0
SHD3_k127_5105003_2 - - - - 0.0000000000000000000000000000000000000000000000000000003355 205.0
SHD3_k127_5105003_3 COG2143 Thioredoxin-related protein - - - 0.000000003392 66.0
SHD3_k127_5118676_0 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 360.0
SHD3_k127_5118676_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002934 306.0
SHD3_k127_5118676_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000001731 223.0
SHD3_k127_5118676_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000121 173.0
SHD3_k127_5118676_4 Ftsk_gamma K03466 - - 0.00000000001943 75.0
SHD3_k127_5118676_5 Protein of unknown function (DUF1194) K07114 - - 0.000002883 60.0
SHD3_k127_5135392_0 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 354.0
SHD3_k127_5135392_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 359.0
SHD3_k127_5135392_2 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 303.0
SHD3_k127_5135392_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - 0.000000000000000000000000000000000000000000000000000000674 214.0
SHD3_k127_5135392_4 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000001989 204.0
SHD3_k127_5135392_5 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000003345 181.0
SHD3_k127_5135392_6 Pfam Periplasmic binding protein K02016,K06858 - - 0.00000000000000000000000000000000001692 147.0
SHD3_k127_5135392_7 phosphorelay signal transduction system - - - 0.0000000000000000000000000000001277 136.0
SHD3_k127_5135392_8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000002397 128.0
SHD3_k127_5135392_9 chlorophyll binding - - - 0.0000000000000000002839 102.0
SHD3_k127_5160883_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 590.0
SHD3_k127_5160883_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 529.0
SHD3_k127_5160883_10 - - - - 0.00000000000000000000000002812 111.0
SHD3_k127_5160883_11 - - - - 0.0000000000003546 73.0
SHD3_k127_5160883_2 Sodium Bile acid symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 469.0
SHD3_k127_5160883_3 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 456.0
SHD3_k127_5160883_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 394.0
SHD3_k127_5160883_5 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000001406 203.0
SHD3_k127_5160883_6 HWE histidine kinase - - - 0.0000000000000000000000000000000000000000000000355 196.0
SHD3_k127_5160883_7 PFAM Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000009537 177.0
SHD3_k127_5160883_8 DoxX - - - 0.000000000000000000000000000000000000000000002199 182.0
SHD3_k127_5160883_9 Dual specificity phosphatase, catalytic domain - - - 0.0000000000000000000000000000000000000001748 160.0
SHD3_k127_5162443_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 615.0
SHD3_k127_5162443_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009609 584.0
SHD3_k127_5162443_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 352.0
SHD3_k127_5162443_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 350.0
SHD3_k127_5162443_4 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001549 276.0
SHD3_k127_5162443_5 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002349 273.0
SHD3_k127_5162443_6 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000002847 100.0
SHD3_k127_5162443_7 Domain of unknown function (DUF309) K09763 - - 0.0000000000000007259 84.0
SHD3_k127_5162443_8 Regulatory protein - - - 0.0000000000000008049 83.0
SHD3_k127_518959_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.141e-258 811.0
SHD3_k127_518959_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 359.0
SHD3_k127_518959_10 YbbR-like protein - - - 0.00000000000000000002377 100.0
SHD3_k127_518959_11 PFAM regulatory protein ArsR - - - 0.000000000000000001447 91.0
SHD3_k127_518959_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000001593 252.0
SHD3_k127_518959_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000001721 217.0
SHD3_k127_518959_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000002162 202.0
SHD3_k127_518959_5 Tautomerase enzyme - - - 0.00000000000000000000000000000000000000001057 156.0
SHD3_k127_518959_6 DinB family - - - 0.0000000000000000000000000000000000002675 145.0
SHD3_k127_518959_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000002973 149.0
SHD3_k127_518959_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000002583 139.0
SHD3_k127_518959_9 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000005027 106.0
SHD3_k127_5201087_0 adenylosuccinate lyase K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 514.0
SHD3_k127_5201087_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 474.0
SHD3_k127_5201087_10 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000001942 263.0
SHD3_k127_5201087_11 Enoyl-CoA hydratase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000001223 252.0
SHD3_k127_5201087_12 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000001341 207.0
SHD3_k127_5201087_13 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000003159 199.0
SHD3_k127_5201087_14 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000001141 198.0
SHD3_k127_5201087_15 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.00000000000000000000000000000000000003746 150.0
SHD3_k127_5201087_16 cheY-homologous receiver domain - - - 0.00000000000000000000000000000008786 141.0
SHD3_k127_5201087_17 - - - - 0.00000000000000000000005705 103.0
SHD3_k127_5201087_18 Acetyl propionyl-CoA carboxylase alpha subunit K01968 - 6.4.1.4 0.000000000000000003643 99.0
SHD3_k127_5201087_19 molybdenum ion binding K07140 - - 0.00000000000000001348 92.0
SHD3_k127_5201087_2 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 460.0
SHD3_k127_5201087_20 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000007638 64.0
SHD3_k127_5201087_21 Desiccation protectant protein Lea14 homolog - GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006952,GO:0008150,GO:0009314,GO:0009416,GO:0009605,GO:0009607,GO:0009611,GO:0009620,GO:0009628,GO:0009642,GO:0009644,GO:0016020,GO:0043207,GO:0044424,GO:0044444,GO:0044464,GO:0048046,GO:0050832,GO:0050896,GO:0051704,GO:0051707,GO:0071944,GO:0098542 - 0.00004571 56.0
SHD3_k127_5201087_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 411.0
SHD3_k127_5201087_4 Aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 385.0
SHD3_k127_5201087_5 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 369.0
SHD3_k127_5201087_6 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 361.0
SHD3_k127_5201087_7 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 347.0
SHD3_k127_5201087_8 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 323.0
SHD3_k127_5201087_9 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 327.0
SHD3_k127_5201428_0 DNA photolyase domain protein K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001012 260.0
SHD3_k127_5201428_1 Small MutS-related domain K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000294 251.0
SHD3_k127_5201428_2 transglycosylase K08309 - - 0.0000000000000000000000000000004923 141.0
SHD3_k127_5201428_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000007515 91.0
SHD3_k127_5201428_4 zinc-ribbon domain - - - 0.0000000006634 71.0
SHD3_k127_5235817_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 340.0
SHD3_k127_5235817_1 Tetratricopeptide repeat - - - 0.000000000000000000000000782 117.0
SHD3_k127_5235817_2 TIGRFAM TonB K03832 - - 0.0000000000000000000001675 106.0
SHD3_k127_5235817_3 oxidoreductase activity - - - 0.00000000000000000029 102.0
SHD3_k127_5239115_0 cellulose binding - - - 2.175e-271 871.0
SHD3_k127_5239115_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 1.056e-253 802.0
SHD3_k127_5239115_10 Protein tyrosine kinase - - - 0.000000000000000000000000000000006669 130.0
SHD3_k127_5239115_11 Chromate resistance exported protein - - - 0.0000000000000000000000001561 123.0
SHD3_k127_5239115_12 - - - - 0.0000000000000000026 85.0
SHD3_k127_5239115_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000002798 91.0
SHD3_k127_5239115_2 Belongs to the peptidase M16 family K07263 - - 1.82e-209 664.0
SHD3_k127_5239115_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.083e-201 666.0
SHD3_k127_5239115_4 Cobalamin-independent synthase, Catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 485.0
SHD3_k127_5239115_5 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 476.0
SHD3_k127_5239115_6 tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 293.0
SHD3_k127_5239115_7 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009923 265.0
SHD3_k127_5239115_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000003685 204.0
SHD3_k127_5239115_9 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000001169 191.0
SHD3_k127_5280835_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.458e-319 995.0
SHD3_k127_5280835_1 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.575e-218 692.0
SHD3_k127_5280835_10 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000000003466 122.0
SHD3_k127_5280835_11 COG3668 Plasmid stabilization system protein - - - 0.000002408 53.0
SHD3_k127_5280835_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 524.0
SHD3_k127_5280835_3 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 475.0
SHD3_k127_5280835_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 346.0
SHD3_k127_5280835_5 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003736 278.0
SHD3_k127_5280835_6 COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000738 258.0
SHD3_k127_5280835_8 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001878 243.0
SHD3_k127_5280835_9 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000003164 123.0
SHD3_k127_5334846_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000002091 220.0
SHD3_k127_5334846_1 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000000000000000000001017 224.0
SHD3_k127_5334846_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000006632 138.0
SHD3_k127_5334846_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000001143 100.0
SHD3_k127_5334846_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000002059 73.0
SHD3_k127_5338743_0 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 420.0
SHD3_k127_5338743_1 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 361.0
SHD3_k127_5338743_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 369.0
SHD3_k127_5338743_3 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000181 238.0
SHD3_k127_5338743_4 Bacterial Ig-like domain (group 3) - - - 0.000000000000000000000000000000000000000000000000000004344 221.0
SHD3_k127_5338743_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000396 194.0
SHD3_k127_5338743_6 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000008394 169.0
SHD3_k127_5338743_7 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000001577 156.0
SHD3_k127_5338743_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000003146 85.0
SHD3_k127_5338743_9 TIGRFAM TonB family protein K03832 - - 0.000009939 58.0
SHD3_k127_5373338_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 337.0
SHD3_k127_5373338_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 325.0
SHD3_k127_5373338_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000006465 127.0
SHD3_k127_5373338_3 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000001419 129.0
SHD3_k127_5373338_4 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.0000000000000001642 93.0
SHD3_k127_5373338_5 Tetratricopeptide repeat - - - 0.00002815 56.0
SHD3_k127_5373712_0 Sortilin, neurotensin receptor 3, - - - 0.0 1341.0
SHD3_k127_5373712_1 Dehydrogenase E1 component K11381 - 1.2.4.4 1.409e-282 885.0
SHD3_k127_5373712_10 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000001054 104.0
SHD3_k127_5373712_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 444.0
SHD3_k127_5373712_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 346.0
SHD3_k127_5373712_4 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 326.0
SHD3_k127_5373712_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000001559 218.0
SHD3_k127_5373712_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000005688 203.0
SHD3_k127_5373712_7 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000004012 177.0
SHD3_k127_5373712_8 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000001595 160.0
SHD3_k127_5373712_9 response to heat K07090 - - 0.00000000000000000000000000000004016 129.0
SHD3_k127_5516038_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 609.0
SHD3_k127_5516038_1 belongs to the aldehyde dehydrogenase family K00137 GO:0003674,GO:0003824,GO:0004029,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019145,GO:0033737,GO:0034641,GO:0042402,GO:0042802,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 1.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 587.0
SHD3_k127_5516038_10 Type III secretion system lipoprotein chaperone (YscW) - - - 0.00000000000005316 81.0
SHD3_k127_5516038_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 561.0
SHD3_k127_5516038_3 Aminotransferase class-III K09251 - 2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 543.0
SHD3_k127_5516038_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 463.0
SHD3_k127_5516038_5 amino acid K03293,K16238,K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 426.0
SHD3_k127_5516038_6 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 337.0
SHD3_k127_5516038_7 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 315.0
SHD3_k127_5516038_8 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000002612 256.0
SHD3_k127_5516038_9 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000339 119.0
SHD3_k127_5546552_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 387.0
SHD3_k127_5546552_1 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 316.0
SHD3_k127_5546552_2 WHG domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005057 257.0
SHD3_k127_5546552_3 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000724 258.0
SHD3_k127_5546552_4 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000007246 238.0
SHD3_k127_5546552_5 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000002068 207.0
SHD3_k127_5546552_6 PFAM secretion protein HlyD K02005 - - 0.00000000000000000006621 101.0
SHD3_k127_5546552_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000003831 83.0
SHD3_k127_5565378_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 413.0
SHD3_k127_5565378_1 PFAM Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000181 238.0
SHD3_k127_5565378_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000003858 205.0
SHD3_k127_5565378_3 Represses a number of genes involved in the response to DNA damage (SOS response) K01356,K03503 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000006856 196.0
SHD3_k127_5565378_4 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000167 149.0
SHD3_k127_5565378_5 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000002466 129.0
SHD3_k127_5565378_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000001331 107.0
SHD3_k127_5565378_7 HI0933-like protein K07007 - - 0.00000000000000000000002468 100.0
SHD3_k127_5565378_8 Thioredoxin-like - - - 0.000001818 59.0
SHD3_k127_5603771_0 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001834 243.0
SHD3_k127_5603771_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000001428 222.0
SHD3_k127_5603771_10 mRNA catabolic process K06950 - - 0.00000000007852 70.0
SHD3_k127_5603771_2 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000001733 194.0
SHD3_k127_5603771_3 ECF sigma factor K03088 - - 0.0000000000000000000000000004166 121.0
SHD3_k127_5603771_4 Pas domain - - - 0.00000000000000000000000006524 118.0
SHD3_k127_5603771_5 PFAM CBS domain containing protein K07168 - - 0.00000000000000000000000006644 112.0
SHD3_k127_5603771_6 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000008015 106.0
SHD3_k127_5603771_7 Metallo-peptidase family M12 - - - 0.000000000000008445 81.0
SHD3_k127_5603771_8 Universal stress protein - - - 0.0000000000002003 73.0
SHD3_k127_5603771_9 Heavy-metal resistance - - - 0.0000000000203 76.0
SHD3_k127_563229_0 MacB-like periplasmic core domain - - - 4.166e-311 978.0
SHD3_k127_563229_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 557.0
SHD3_k127_563229_10 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000001542 177.0
SHD3_k127_563229_11 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000005052 169.0
SHD3_k127_563229_12 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000001424 107.0
SHD3_k127_563229_13 PFAM PKD domain containing protein - - - 0.0000000000000000005398 99.0
SHD3_k127_563229_14 Cytochrome c - - - 0.0000000000000000005449 93.0
SHD3_k127_563229_15 - - - - 0.00001613 51.0
SHD3_k127_563229_16 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000776 48.0
SHD3_k127_563229_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 547.0
SHD3_k127_563229_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 439.0
SHD3_k127_563229_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 427.0
SHD3_k127_563229_5 Belongs to the OprB family K16080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 406.0
SHD3_k127_563229_6 C-terminal AAA-associated domain K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 399.0
SHD3_k127_563229_7 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 318.0
SHD3_k127_563229_8 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002817 254.0
SHD3_k127_563229_9 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001225 222.0
SHD3_k127_57132_0 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 526.0
SHD3_k127_57132_1 esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 452.0
SHD3_k127_57132_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 445.0
SHD3_k127_57132_3 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 376.0
SHD3_k127_57132_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 340.0
SHD3_k127_57132_5 MgtE intracellular - - - 0.0000000000000000000000000000000000000000000000000000000000000000002499 257.0
SHD3_k127_57132_6 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.0000000000000000000000000000000000000000000007299 172.0
SHD3_k127_57132_7 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000000000002002 168.0
SHD3_k127_57132_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000006042 167.0
SHD3_k127_57132_9 PFAM Peptidase M1 membrane alanine aminopeptidase - - - 0.00000000000000006343 95.0
SHD3_k127_5714844_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 510.0
SHD3_k127_5714844_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 359.0
SHD3_k127_5714844_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 368.0
SHD3_k127_5714844_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000004613 252.0
SHD3_k127_5714844_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000002191 215.0
SHD3_k127_5714844_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000006536 54.0
SHD3_k127_5714844_6 YbbR family - - - 0.000002598 60.0
SHD3_k127_596563_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 392.0
SHD3_k127_596563_1 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 320.0
SHD3_k127_596563_2 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000003013 244.0
SHD3_k127_596563_3 outer membrane efflux protein - - - 0.0000000000000000002959 96.0
SHD3_k127_613231_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 328.0
SHD3_k127_613231_1 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000001267 158.0
SHD3_k127_613231_2 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000003339 157.0
SHD3_k127_613231_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000121 152.0
SHD3_k127_617110_0 Protein kinase domain K12132 - 2.7.11.1 1.777e-230 749.0
SHD3_k127_617110_1 Protein kinase domain K12132 - 2.7.11.1 1.934e-211 689.0
SHD3_k127_617110_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 600.0
SHD3_k127_617110_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 554.0
SHD3_k127_617110_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 504.0
SHD3_k127_617110_5 HEPN domain - - - 0.000000000000000000007115 103.0
SHD3_k127_617110_6 nucleotidyltransferase activity - - - 0.000007176 55.0
SHD3_k127_626030_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 379.0
SHD3_k127_626030_1 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 334.0
SHD3_k127_626030_2 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000209 185.0
SHD3_k127_626030_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.00000000000000000009428 91.0
SHD3_k127_626030_4 ATPases associated with a variety of cellular activities K01990 - - 0.00004194 54.0
SHD3_k127_681490_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 9.578e-202 652.0
SHD3_k127_681490_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 338.0
SHD3_k127_681490_2 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 292.0
SHD3_k127_681490_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 267.0
SHD3_k127_681490_4 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000002565 281.0
SHD3_k127_681490_5 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000001165 208.0
SHD3_k127_681490_6 PFAM Transcriptional regulator - - - 0.0000000000000006009 87.0
SHD3_k127_681490_7 - - - - 0.000002653 60.0
SHD3_k127_681490_8 Domain of unknown function (DUF4149) - - - 0.000003616 59.0
SHD3_k127_681490_9 - - - - 0.00001086 54.0
SHD3_k127_687374_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 2.264e-269 861.0
SHD3_k127_687374_1 Cyclic nucleotide-monophosphate binding domain - - - 8.099e-201 634.0
SHD3_k127_687374_2 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 370.0
SHD3_k127_687374_3 Amidohydrolase family - - - 0.0000005968 56.0
SHD3_k127_687374_4 Tetratricopeptide repeat - - - 0.00001173 56.0
SHD3_k127_7342_0 Prolyl oligopeptidase family - - - 1.289e-261 838.0
SHD3_k127_7342_1 Protein of unknown function, DUF255 K06888 - - 1.549e-196 634.0
SHD3_k127_7342_10 YceG-like family K07082 - - 0.000000000000000000000000000000000000000000000000000000000003004 228.0
SHD3_k127_7342_11 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000004062 207.0
SHD3_k127_7342_12 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000009486 216.0
SHD3_k127_7342_13 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000001389 196.0
SHD3_k127_7342_14 Glycosyl transferase family 2 - - - 0.00000000000000000000000000005038 132.0
SHD3_k127_7342_15 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.00000000000000000000006261 116.0
SHD3_k127_7342_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00172,K00441,K03522 - 1.12.98.1,1.2.7.1 0.0000000000000000000004931 109.0
SHD3_k127_7342_17 Cytochrome b(C-terminal)/b6/petD - - - 0.00000000000000000001803 97.0
SHD3_k127_7342_18 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000002305 81.0
SHD3_k127_7342_19 protein kinase activity - - - 0.0000000000000705 85.0
SHD3_k127_7342_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 449.0
SHD3_k127_7342_20 PBS lyase HEAT-like repeat - - - 0.00000000008223 73.0
SHD3_k127_7342_21 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.0000000001673 72.0
SHD3_k127_7342_22 Phosphoserine phosphatase - - - 0.0002433 55.0
SHD3_k127_7342_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 449.0
SHD3_k127_7342_4 PFAM Cytochrome b b6 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 400.0
SHD3_k127_7342_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 408.0
SHD3_k127_7342_6 Coenzyme A transferase K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 359.0
SHD3_k127_7342_7 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 312.0
SHD3_k127_7342_8 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 339.0
SHD3_k127_7342_9 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000003764 246.0
SHD3_k127_735657_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.076e-275 877.0
SHD3_k127_735657_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 553.0
SHD3_k127_735657_10 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000001586 108.0
SHD3_k127_735657_11 Peptidase MA superfamily - - - 0.00000000000000000008984 103.0
SHD3_k127_735657_12 Protein of unknown function (DUF2662) - - - 0.0000000000005693 78.0
SHD3_k127_735657_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000002324 59.0
SHD3_k127_735657_14 Tetratricopeptide TPR_2 repeat protein - - - 0.00001292 57.0
SHD3_k127_735657_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 481.0
SHD3_k127_735657_3 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 441.0
SHD3_k127_735657_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 372.0
SHD3_k127_735657_5 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000256 300.0
SHD3_k127_735657_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002327 301.0
SHD3_k127_735657_7 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003641 238.0
SHD3_k127_735657_8 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000008583 126.0
SHD3_k127_735657_9 oxidoreductase activity - - - 0.00000000000000000000006122 115.0
SHD3_k127_761876_0 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000002586 155.0
SHD3_k127_761876_1 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000001296 154.0
SHD3_k127_761876_2 - K07018 - - 0.0000000000000000000000000000000008454 143.0
SHD3_k127_761876_3 SpoU rRNA Methylase family K03437 - - 0.00000000000000000000000000000003915 135.0
SHD3_k127_761876_4 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.00000000000000000000000000004406 120.0
SHD3_k127_769010_0 DEAD DEAH box K03724 - - 0.0 1708.0
SHD3_k127_769010_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 310.0
SHD3_k127_769010_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000003316 243.0
SHD3_k127_769010_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000001284 136.0
SHD3_k127_769010_4 Domain of unknown function (DUF4142) K08995 - - 0.000000000000000000000000000000005259 146.0
SHD3_k127_769010_5 AI-2E family transporter - - - 0.000000000000000000000007716 115.0
SHD3_k127_769010_7 Protein of unknown function (DUF1328) - - - 0.0005491 44.0
SHD3_k127_773831_0 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 457.0
SHD3_k127_773831_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 311.0
SHD3_k127_773831_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001695 282.0
SHD3_k127_773831_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001006 250.0
SHD3_k127_773831_4 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000001558 205.0
SHD3_k127_773831_5 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000002347 151.0
SHD3_k127_773831_6 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000143 110.0
SHD3_k127_773831_7 Domain of unknown function (DUF3488) - - - 0.0000000000000000000001397 115.0
SHD3_k127_789788_0 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 419.0
SHD3_k127_789788_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 372.0
SHD3_k127_789788_10 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000001549 221.0
SHD3_k127_789788_11 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000296 201.0
SHD3_k127_789788_12 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000001084 169.0
SHD3_k127_789788_13 - K07018 - - 0.0000000000000000000000000000000000000001998 158.0
SHD3_k127_789788_14 OmpA family K03640 - - 0.00000000000000000000000000000000000003729 151.0
SHD3_k127_789788_15 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000000008071 132.0
SHD3_k127_789788_16 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000001766 126.0
SHD3_k127_789788_17 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000003047 129.0
SHD3_k127_789788_18 TIGRFAM folate-binding protein YgfZ K06980 - - 0.000000000000000000000000003905 121.0
SHD3_k127_789788_19 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000003347 112.0
SHD3_k127_789788_2 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 333.0
SHD3_k127_789788_20 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000000000000002098 110.0
SHD3_k127_789788_21 Outer membrane lipoprotein - - - 0.0000000000000000000003648 111.0
SHD3_k127_789788_22 thiolester hydrolase activity K17362 - - 0.000000000000003778 86.0
SHD3_k127_789788_23 Ribosomal protein S20 K02968 - - 0.00000000002853 67.0
SHD3_k127_789788_24 TIGRFAM TonB K03832 - - 0.00000008358 63.0
SHD3_k127_789788_3 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 329.0
SHD3_k127_789788_4 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 310.0
SHD3_k127_789788_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002875 260.0
SHD3_k127_789788_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003332 246.0
SHD3_k127_789788_7 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000006969 248.0
SHD3_k127_789788_8 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000009767 248.0
SHD3_k127_789788_9 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000001225 209.0
SHD3_k127_792928_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 355.0
SHD3_k127_792928_1 Mo-co oxidoreductase dimerisation domain K00387 - 1.8.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 291.0
SHD3_k127_792928_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000003878 183.0
SHD3_k127_792928_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000001154 152.0
SHD3_k127_792928_4 MoaE protein K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000001221 129.0
SHD3_k127_792928_5 belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 0.0000000000000000000000000000008044 126.0
SHD3_k127_792928_6 MoaE protein K21142 - 2.8.1.12 0.000000000006677 68.0
SHD3_k127_792928_7 Cytochrome c K03889 - - 0.00000003729 66.0
SHD3_k127_792928_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000007562 48.0
SHD3_k127_792928_9 Acts as a magnesium transporter K06213 - - 0.00006071 55.0
SHD3_k127_810065_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 4.116e-284 882.0
SHD3_k127_810065_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 3.905e-274 862.0
SHD3_k127_810065_10 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000001005 89.0
SHD3_k127_810065_11 nickel cation binding K04651 - - 0.0000000000004846 75.0
SHD3_k127_810065_2 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 508.0
SHD3_k127_810065_3 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 363.0
SHD3_k127_810065_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 318.0
SHD3_k127_810065_5 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 301.0
SHD3_k127_810065_6 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000006236 220.0
SHD3_k127_810065_7 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.00000000000000000000000000000000000001739 166.0
SHD3_k127_810065_8 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.00000000000000000000000000000000000004932 150.0
SHD3_k127_810065_9 carbon dioxide binding K04653,K04654 - - 0.0000000000000000000001095 115.0
SHD3_k127_830907_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 479.0
SHD3_k127_830907_1 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 422.0
SHD3_k127_830907_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 419.0
SHD3_k127_830907_3 Amino acid permease K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 406.0
SHD3_k127_830907_4 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 404.0
SHD3_k127_830907_5 polysaccharide catabolic process K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 356.0
SHD3_k127_830907_6 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 295.0
SHD3_k127_830907_7 PFAM Abortive infection protein - - - 0.00000000000000000000000000000000000000000000000001651 185.0
SHD3_k127_830907_8 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000000001226 181.0
SHD3_k127_830907_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000002127 100.0
SHD3_k127_83635_0 synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 490.0
SHD3_k127_83635_1 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 481.0
SHD3_k127_83635_10 Thioesterase superfamily K18014 - 4.3.1.14 0.000000000000000000000000000000000000000006547 168.0
SHD3_k127_83635_11 transglycosylase K08309 - - 0.000000000000000000000000000000001318 148.0
SHD3_k127_83635_12 Beta-lactamase - - - 0.000000000000000000000000000007834 125.0
SHD3_k127_83635_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 426.0
SHD3_k127_83635_3 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 397.0
SHD3_k127_83635_4 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 347.0
SHD3_k127_83635_5 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 351.0
SHD3_k127_83635_6 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 311.0
SHD3_k127_83635_7 Tyrosine recombinase xerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002032 288.0
SHD3_k127_83635_8 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000177 259.0
SHD3_k127_83635_9 B12 binding domain K18011 - 5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006207 256.0
SHD3_k127_870171_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 4.222e-204 655.0
SHD3_k127_870171_1 Dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 398.0
SHD3_k127_870171_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 357.0
SHD3_k127_870171_3 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 349.0
SHD3_k127_870171_4 Sigma-70 region 2 K03088 - - 0.00000000000009379 83.0
SHD3_k127_870171_5 Cysteine dioxygenase type I - - - 0.000000000225 69.0
SHD3_k127_870171_6 LTXXQ motif family protein - - - 0.00006775 53.0
SHD3_k127_877791_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 595.0
SHD3_k127_877791_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 318.0
SHD3_k127_877791_2 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008611 284.0
SHD3_k127_877791_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001135 244.0
SHD3_k127_877791_4 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000001466 199.0
SHD3_k127_877791_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000001531 132.0
SHD3_k127_877791_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000007297 123.0
SHD3_k127_877791_7 Roadblock/LC7 domain - - - 0.000000000157 66.0
SHD3_k127_877791_8 Tetratricopeptide repeats - - - 0.000001045 61.0
SHD3_k127_877791_9 G-protein coupled GABA receptor activity - - - 0.00008775 55.0
SHD3_k127_878972_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1190.0
SHD3_k127_878972_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 585.0
SHD3_k127_878972_10 LAO AO transport system K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 310.0
SHD3_k127_878972_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002804 280.0
SHD3_k127_878972_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000001513 217.0
SHD3_k127_878972_13 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000006551 226.0
SHD3_k127_878972_14 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000009401 195.0
SHD3_k127_878972_15 GHMP kinase K00869,K07031 - 2.7.1.168,2.7.1.36 0.0000000000000000000000000000000000000000000000001244 189.0
SHD3_k127_878972_16 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000003199 199.0
SHD3_k127_878972_17 Cupin domain - - - 0.00000000000000000000000000000000000000000000002403 173.0
SHD3_k127_878972_18 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.000000000000000000000000000000000000008214 163.0
SHD3_k127_878972_19 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000001987 160.0
SHD3_k127_878972_2 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 569.0
SHD3_k127_878972_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000006086 103.0
SHD3_k127_878972_21 - - - - 0.000000000000000000001373 108.0
SHD3_k127_878972_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000002008 94.0
SHD3_k127_878972_23 - - - - 0.00000000000002812 84.0
SHD3_k127_878972_24 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00007067 55.0
SHD3_k127_878972_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 561.0
SHD3_k127_878972_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 486.0
SHD3_k127_878972_5 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 471.0
SHD3_k127_878972_6 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 449.0
SHD3_k127_878972_7 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 462.0
SHD3_k127_878972_8 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 382.0
SHD3_k127_878972_9 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 350.0
SHD3_k127_915011_0 PASTA domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 437.0
SHD3_k127_915011_1 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 404.0
SHD3_k127_915011_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003613 286.0
SHD3_k127_915011_3 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000007227 152.0
SHD3_k127_915011_4 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000005166 108.0
SHD3_k127_915011_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.000004603 53.0
SHD3_k127_924671_0 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 495.0
SHD3_k127_924671_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 428.0
SHD3_k127_924671_10 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000002691 143.0
SHD3_k127_924671_11 Cell division protein FtsQ K03589 - - 0.0000000000436 72.0
SHD3_k127_924671_12 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.000001749 55.0
SHD3_k127_924671_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 420.0
SHD3_k127_924671_3 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 426.0
SHD3_k127_924671_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 382.0
SHD3_k127_924671_5 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 382.0
SHD3_k127_924671_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 319.0
SHD3_k127_924671_7 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 301.0
SHD3_k127_924671_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000208 279.0
SHD3_k127_924671_9 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000002773 260.0
SHD3_k127_931898_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 9.4e-322 1021.0
SHD3_k127_931898_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.479e-297 924.0
SHD3_k127_931898_10 membrane K08972 - - 0.000000000000000000000000003545 114.0
SHD3_k127_931898_2 Domain of unknown function (DUF3536) - - - 1.847e-293 953.0
SHD3_k127_931898_3 Alpha-glucan phosphorylase K00688 - 2.4.1.1 7.257e-222 715.0
SHD3_k127_931898_4 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 527.0
SHD3_k127_931898_5 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 337.0
SHD3_k127_931898_6 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 315.0
SHD3_k127_931898_7 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001371 283.0
SHD3_k127_931898_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001276 271.0
SHD3_k127_931898_9 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000596 141.0
SHD3_k127_975001_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 399.0
SHD3_k127_975001_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 403.0
SHD3_k127_975001_2 PFAM Formiminotransferase K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 359.0
SHD3_k127_975001_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000004748 245.0
SHD3_k127_975001_4 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000001762 171.0
SHD3_k127_975001_5 Diguanylate cyclase - - - 0.0000000000000000756 82.0
SHD3_k127_975001_6 FR47-like protein K03789 - 2.3.1.128 0.00000000000001445 84.0