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Overview

ID MAG03392
Name SHD3_bin.19
Sample SMP0084
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus Sulfobium
Species
Assembly information
Completeness (%) 99.98
Contamination (%) 4.07
GC content (%) 51.0
N50 (bp) 12,456
Genome size (bp) 3,568,334

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3390

Gene name Description KEGG GOs EC E-value Score Sequence
SHD3_k127_102244_0 C oxidoreductase subunit A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 422.0
SHD3_k127_102244_1 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000002418 193.0
SHD3_k127_102244_2 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000000000000000000000003144 153.0
SHD3_k127_102244_3 Ribbon-helix-helix protein, copG family - - - 0.00000000000000000001912 93.0
SHD3_k127_102244_4 Cytochrome c - - - 0.0000000000000001079 83.0
SHD3_k127_102244_5 FHA Domain - - - 0.0000000000000006704 83.0
SHD3_k127_10331_0 PFAM Radical SAM - - - 1.439e-212 671.0
SHD3_k127_10331_1 glucose sorbosone K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 440.0
SHD3_k127_10331_10 Histone deacetylase domain K04768 - - 0.0000002493 52.0
SHD3_k127_10331_11 - - - - 0.00002766 52.0
SHD3_k127_10331_2 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 370.0
SHD3_k127_10331_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 328.0
SHD3_k127_10331_4 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000000002383 206.0
SHD3_k127_10331_5 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000074 136.0
SHD3_k127_10331_6 Histone deacetylase domain K04768 - - 0.00000000000000000000000000002944 120.0
SHD3_k127_10331_7 TGS domain K06944 - - 0.00000000000000000008307 89.0
SHD3_k127_10331_8 gas vesicle protein - - - 0.0000000000000000001047 93.0
SHD3_k127_10331_9 Protein of unknown function (DUF1264) - - - 0.000000000000002086 83.0
SHD3_k127_1050628_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 6.766e-313 974.0
SHD3_k127_1050628_1 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 478.0
SHD3_k127_1050628_10 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000009549 184.0
SHD3_k127_1050628_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000000109 179.0
SHD3_k127_1050628_12 Subtilase family - - - 0.0000000000000000000000000001353 124.0
SHD3_k127_1050628_2 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 427.0
SHD3_k127_1050628_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 430.0
SHD3_k127_1050628_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 421.0
SHD3_k127_1050628_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 400.0
SHD3_k127_1050628_6 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 394.0
SHD3_k127_1050628_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 391.0
SHD3_k127_1050628_8 Signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 357.0
SHD3_k127_1050628_9 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 287.0
SHD3_k127_1061206_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 360.0
SHD3_k127_1061206_1 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000001165 178.0
SHD3_k127_1061206_2 - - - - 0.0000000000000004847 85.0
SHD3_k127_1062120_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 5.7e-313 982.0
SHD3_k127_1062120_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000001585 234.0
SHD3_k127_1062120_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000006518 98.0
SHD3_k127_1062120_3 - - - - 0.0000000000001168 76.0
SHD3_k127_1062120_4 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000005743 69.0
SHD3_k127_107002_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 475.0
SHD3_k127_107002_1 Cytochrome P460 - - - 0.0000000000000000000000000000000000002111 147.0
SHD3_k127_107002_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000974 62.0
SHD3_k127_10962_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 448.0
SHD3_k127_10962_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 354.0
SHD3_k127_10962_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000003628 231.0
SHD3_k127_10962_3 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000001159 191.0
SHD3_k127_10962_4 Aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.00000002226 58.0
SHD3_k127_1112048_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 440.0
SHD3_k127_1112048_1 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 337.0
SHD3_k127_1131431_0 photosystem II stabilization K02237 - - 0.000000000000000000000000000000000000000000000002679 184.0
SHD3_k127_1131431_1 - - - - 0.0000000000000000000000000000009001 123.0
SHD3_k127_118778_0 Aminotransferase class I and II K14261 - - 1.829e-213 671.0
SHD3_k127_118778_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 603.0
SHD3_k127_118778_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000001497 202.0
SHD3_k127_118778_11 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000001387 158.0
SHD3_k127_118778_12 Nitroreductase family - - - 0.000000000000000000000000000000006757 136.0
SHD3_k127_118778_13 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000007043 119.0
SHD3_k127_118778_14 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001245 107.0
SHD3_k127_118778_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 539.0
SHD3_k127_118778_3 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 412.0
SHD3_k127_118778_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 331.0
SHD3_k127_118778_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 329.0
SHD3_k127_118778_6 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003477 251.0
SHD3_k127_118778_7 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000008116 240.0
SHD3_k127_118778_8 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000001146 225.0
SHD3_k127_118778_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000001234 210.0
SHD3_k127_120066_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000874 265.0
SHD3_k127_120066_1 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000001855 204.0
SHD3_k127_120066_2 - - - - 0.00000000000000000000000006037 119.0
SHD3_k127_120066_3 lysyltransferase activity K07027,K20468 - - 0.00000000000000000000003355 111.0
SHD3_k127_120066_4 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0004135 53.0
SHD3_k127_121643_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000009596 226.0
SHD3_k127_121643_1 Methyltransferase domain - - - 0.0000000000000000000000000000008402 130.0
SHD3_k127_121643_2 - - - - 0.0000009344 54.0
SHD3_k127_1218072_0 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 532.0
SHD3_k127_1218072_1 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 346.0
SHD3_k127_1218072_2 RecF/RecN/SMC N terminal domain K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005257 245.0
SHD3_k127_1218072_3 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000004603 226.0
SHD3_k127_1218072_4 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.0000000000000000000000000001621 116.0
SHD3_k127_1218072_5 PFAM Thioredoxin K03671 - - 0.0000000000000000000009341 99.0
SHD3_k127_1218072_6 response to heat K07090 - - 0.000000000000003561 76.0
SHD3_k127_1218072_7 Carboxymuconolactone decarboxylase family - - - 0.000000000003047 70.0
SHD3_k127_1218072_8 - - - - 0.000000000003094 68.0
SHD3_k127_125657_0 Putative endonuclease, protein of unknown function (DUF1780) - - - 0.0000000000000000005722 94.0
SHD3_k127_1291951_0 pathogenesis K13669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 321.0
SHD3_k127_1291951_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 303.0
SHD3_k127_1291951_2 CAAX protease self-immunity K07052 - - 0.0000000003456 68.0
SHD3_k127_1298371_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 445.0
SHD3_k127_130973_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000006057 210.0
SHD3_k127_130973_1 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000005594 168.0
SHD3_k127_130973_2 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000001524 142.0
SHD3_k127_130973_3 Thiopurine S-methyltransferase (TPMT) - - - 0.0000002767 63.0
SHD3_k127_1366562_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 610.0
SHD3_k127_1366562_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 597.0
SHD3_k127_1366562_10 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000004013 240.0
SHD3_k127_1366562_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000001179 129.0
SHD3_k127_1366562_12 - - - - 0.0000000000002277 73.0
SHD3_k127_1366562_13 Domain of Unknown Function (DUF350) - - - 0.00000000004698 65.0
SHD3_k127_1366562_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 551.0
SHD3_k127_1366562_3 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 529.0
SHD3_k127_1366562_4 oxidoreductase activity K00316 - 1.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 529.0
SHD3_k127_1366562_5 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 483.0
SHD3_k127_1366562_6 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 464.0
SHD3_k127_1366562_7 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 302.0
SHD3_k127_1366562_8 Spermidine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006964 279.0
SHD3_k127_1366562_9 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001956 274.0
SHD3_k127_138455_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.149e-287 903.0
SHD3_k127_138455_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 1.154e-201 635.0
SHD3_k127_138455_10 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 343.0
SHD3_k127_138455_11 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 325.0
SHD3_k127_138455_12 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 330.0
SHD3_k127_138455_13 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 304.0
SHD3_k127_138455_14 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 292.0
SHD3_k127_138455_15 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000205 297.0
SHD3_k127_138455_16 Type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002417 292.0
SHD3_k127_138455_17 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 268.0
SHD3_k127_138455_18 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000006707 250.0
SHD3_k127_138455_19 metal ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000006081 239.0
SHD3_k127_138455_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 596.0
SHD3_k127_138455_20 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000003633 234.0
SHD3_k127_138455_21 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000495 211.0
SHD3_k127_138455_22 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.0000000000000000000000000000000000000000000001397 173.0
SHD3_k127_138455_23 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000001493 158.0
SHD3_k127_138455_24 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000006899 137.0
SHD3_k127_138455_25 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000002832 108.0
SHD3_k127_138455_26 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000001014 89.0
SHD3_k127_138455_27 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.00000000000000000231 92.0
SHD3_k127_138455_28 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000003969 86.0
SHD3_k127_138455_29 Pilus assembly protein, PilP K02665 - - 0.000000000008074 72.0
SHD3_k127_138455_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 576.0
SHD3_k127_138455_30 protein secretion K03116,K03117 - - 0.000000001775 61.0
SHD3_k127_138455_32 Pilus assembly protein, PilO K02664 - - 0.000000003 65.0
SHD3_k127_138455_33 PFAM Fimbrial assembly K02663 - - 0.00000002824 62.0
SHD3_k127_138455_4 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 549.0
SHD3_k127_138455_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 496.0
SHD3_k127_138455_6 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 430.0
SHD3_k127_138455_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 389.0
SHD3_k127_138455_8 pathogenesis K13669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 378.0
SHD3_k127_138455_9 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 375.0
SHD3_k127_1437779_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000008107 147.0
SHD3_k127_1439417_0 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 9.149e-205 643.0
SHD3_k127_1439417_1 PFAM DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005754 281.0
SHD3_k127_1439417_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000001296 229.0
SHD3_k127_1440613_0 - - - - 0.0000000000000000000000000000000000008204 147.0
SHD3_k127_1440613_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000004786 132.0
SHD3_k127_1442281_0 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000005629 161.0
SHD3_k127_1442281_1 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000004083 96.0
SHD3_k127_1442281_2 COG NOG15344 non supervised orthologous group - - - 0.00000000001761 68.0
SHD3_k127_1442281_3 - - - - 0.000000009335 58.0
SHD3_k127_1442488_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 585.0
SHD3_k127_1442488_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18903 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 519.0
SHD3_k127_1442488_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 445.0
SHD3_k127_1442488_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000001292 207.0
SHD3_k127_1442488_4 Adenylate kinase - - - 0.0000000000000000000000000000000000000000000000001022 183.0
SHD3_k127_1442488_5 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000009559 147.0
SHD3_k127_1442488_6 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000001964 74.0
SHD3_k127_1442667_0 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002208 257.0
SHD3_k127_1442667_1 CHRD domain - - - 0.0000000000000000000000000000000000001684 146.0
SHD3_k127_1442667_3 Membrane - - - 0.0000000000000000001198 99.0
SHD3_k127_1442667_4 Glycoside hydrolase 15-related - - - 0.000000000000000005159 84.0
SHD3_k127_1442667_5 hyperosmotic response K04065 - - 0.000000000001557 74.0
SHD3_k127_1442667_6 Membrane - - - 0.00000007453 63.0
SHD3_k127_1457105_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 373.0
SHD3_k127_1457105_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 310.0
SHD3_k127_1457105_2 Transglycosylase associated protein - - - 0.0000000003452 63.0
SHD3_k127_145790_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.651e-203 637.0
SHD3_k127_145790_1 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 501.0
SHD3_k127_145790_10 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000001425 146.0
SHD3_k127_145790_11 Autoinducer synthase - - - 0.0000000000000000000000000000002661 132.0
SHD3_k127_145790_12 COG3209 Rhs family protein - - - 0.0000000000001953 84.0
SHD3_k127_145790_13 - K06039,K07092 - - 0.000002079 55.0
SHD3_k127_145790_2 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 415.0
SHD3_k127_145790_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 355.0
SHD3_k127_145790_4 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 340.0
SHD3_k127_145790_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 332.0
SHD3_k127_145790_6 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 311.0
SHD3_k127_145790_7 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000101 231.0
SHD3_k127_145790_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000005372 166.0
SHD3_k127_145790_9 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000002845 174.0
SHD3_k127_1460634_0 Tetratricopeptide repeat - - - 1.464e-242 779.0
SHD3_k127_1460634_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.064e-205 658.0
SHD3_k127_1460634_10 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002767 273.0
SHD3_k127_1460634_11 Transcription termination factor nusG - - - 0.0000000000000000000000000000000000000000000000000002106 190.0
SHD3_k127_1460634_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000003986 184.0
SHD3_k127_1460634_13 - - - - 0.00000000000000000000000001247 113.0
SHD3_k127_1460634_14 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.0000000000001373 74.0
SHD3_k127_1460634_2 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 529.0
SHD3_k127_1460634_3 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 509.0
SHD3_k127_1460634_4 AAA domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 385.0
SHD3_k127_1460634_5 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 379.0
SHD3_k127_1460634_6 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 318.0
SHD3_k127_1460634_7 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 304.0
SHD3_k127_1460634_8 AAA domain K08252 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 301.0
SHD3_k127_1460634_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002267 291.0
SHD3_k127_1462907_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.437e-276 863.0
SHD3_k127_1462907_1 membrane transporter protein K07090 - - 6.573e-204 642.0
SHD3_k127_1462907_2 isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 458.0
SHD3_k127_1462907_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001306 263.0
SHD3_k127_1462907_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000005471 191.0
SHD3_k127_1462907_5 PFAM UspA - - - 0.00000000000000000000000000000000000000000000000001384 190.0
SHD3_k127_1462907_6 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000001422 128.0
SHD3_k127_1462907_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000008842 69.0
SHD3_k127_1462909_0 Histidine kinase K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005625 284.0
SHD3_k127_1464647_0 Zinc-binding dehydrogenase K12957,K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 492.0
SHD3_k127_1464647_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 491.0
SHD3_k127_1464647_2 helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 454.0
SHD3_k127_1468182_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 391.0
SHD3_k127_1468182_1 PBP superfamily domain K02040 - - 0.000000000000000000000000000000001664 134.0
SHD3_k127_1468631_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 445.0
SHD3_k127_1468631_1 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000006278 147.0
SHD3_k127_1468631_2 sulfur relay protein TusB DsrH K07237 - - 0.0000002969 55.0
SHD3_k127_1468631_3 Belongs to the DsrF TusC family K07236 - - 0.00004705 51.0
SHD3_k127_1468631_4 DsrE/DsrF-like family K07235 - - 0.0009967 46.0
SHD3_k127_1471975_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 341.0
SHD3_k127_1471975_1 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 310.0
SHD3_k127_1471975_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000008153 256.0
SHD3_k127_1471975_3 - - - - 0.000000000000000000000001453 106.0
SHD3_k127_1471975_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system - - - 0.0000000000003062 70.0
SHD3_k127_1475726_0 Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 289.0
SHD3_k127_1478840_0 Phosphoglycerate kinase K00927 - 2.7.2.3 9.996e-200 628.0
SHD3_k127_1478840_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 517.0
SHD3_k127_1478840_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 482.0
SHD3_k127_1478840_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 431.0
SHD3_k127_1478840_4 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 372.0
SHD3_k127_1478840_5 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000000000000000000000001623 226.0
SHD3_k127_1478840_6 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000001307 214.0
SHD3_k127_1478840_7 - - - - 0.00000000000000000000000000000000000000000000000405 184.0
SHD3_k127_1478840_8 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000461 159.0
SHD3_k127_14806_0 Belongs to the 'phage' integrase family - - - 0.00007774 45.0
SHD3_k127_14842_0 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 568.0
SHD3_k127_14842_1 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 452.0
SHD3_k127_14842_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 411.0
SHD3_k127_14842_3 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 394.0
SHD3_k127_14842_4 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 355.0
SHD3_k127_14842_5 Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 354.0
SHD3_k127_14842_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 292.0
SHD3_k127_14842_7 Calcineurin-like phosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000009208 225.0
SHD3_k127_1484648_0 Glycine/sarcosine/betaine reductase component B subunits K10671 - 1.21.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 447.0
SHD3_k127_1484648_1 Glycine reductase complex component B subunit gamma K10672 - 1.21.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 422.0
SHD3_k127_1484648_2 glycine betaine sarcosine D-proline reductase family K10672,K21579 - 1.21.4.2,1.21.4.4 0.000000000000000000000000000000000003947 138.0
SHD3_k127_1484648_3 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.00000001956 58.0
SHD3_k127_1485_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.204e-286 895.0
SHD3_k127_1485_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 429.0
SHD3_k127_1485_2 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 381.0
SHD3_k127_1485_3 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 357.0
SHD3_k127_1485_4 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 327.0
SHD3_k127_1485_5 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000002567 189.0
SHD3_k127_1485_6 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000003667 168.0
SHD3_k127_1485_7 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000001437 129.0
SHD3_k127_1486263_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000000000000000000000000003156 186.0
SHD3_k127_149097_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1240.0
SHD3_k127_149097_1 Telomere recombination K04656 - - 3.172e-246 785.0
SHD3_k127_149097_10 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 374.0
SHD3_k127_149097_11 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 356.0
SHD3_k127_149097_12 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 321.0
SHD3_k127_149097_13 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003403 289.0
SHD3_k127_149097_14 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001127 284.0
SHD3_k127_149097_15 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000003132 262.0
SHD3_k127_149097_16 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000785 253.0
SHD3_k127_149097_17 Vitamin K epoxide reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001785 249.0
SHD3_k127_149097_18 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000000005945 213.0
SHD3_k127_149097_19 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000001978 206.0
SHD3_k127_149097_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.391e-222 727.0
SHD3_k127_149097_20 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000003073 189.0
SHD3_k127_149097_21 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000000002372 149.0
SHD3_k127_149097_22 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000004125 138.0
SHD3_k127_149097_23 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000003189 127.0
SHD3_k127_149097_24 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000004414 114.0
SHD3_k127_149097_25 PAS domain containing protein K03406,K13924,K14986 - 2.1.1.80,2.7.13.3,3.1.1.61 0.00000000000000000001114 93.0
SHD3_k127_149097_26 - - - - 0.00000000000000002774 87.0
SHD3_k127_149097_27 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.000000000000003757 85.0
SHD3_k127_149097_28 curli production assembly transport component CsgG - - - 0.0000009282 62.0
SHD3_k127_149097_29 Putative zinc- or iron-chelating domain K06940 - - 0.00006468 51.0
SHD3_k127_149097_3 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 531.0
SHD3_k127_149097_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 495.0
SHD3_k127_149097_5 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 457.0
SHD3_k127_149097_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 423.0
SHD3_k127_149097_7 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 407.0
SHD3_k127_149097_8 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 368.0
SHD3_k127_149097_9 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 356.0
SHD3_k127_149857_0 Elongation factor SelB, winged helix K03833 - - 4.076e-210 670.0
SHD3_k127_149857_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 529.0
SHD3_k127_149857_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 447.0
SHD3_k127_149857_3 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 327.0
SHD3_k127_149857_4 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 317.0
SHD3_k127_149857_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001453 286.0
SHD3_k127_149857_6 NTPase - - - 0.0000000000000000000000000000000000000001574 156.0
SHD3_k127_149857_8 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000003085 129.0
SHD3_k127_149857_9 general secretion pathway protein K02246,K02456 - - 0.000006591 53.0
SHD3_k127_1498749_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0 1138.0
SHD3_k127_1498749_1 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 323.0
SHD3_k127_1498749_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000001934 159.0
SHD3_k127_1504381_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000001195 132.0
SHD3_k127_1504381_1 - - - - 0.00003149 46.0
SHD3_k127_1504381_2 Major facilitator superfamily - - - 0.0008789 47.0
SHD3_k127_1506254_0 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000003232 195.0
SHD3_k127_1506254_1 PFAM thiamineS protein - - - 0.00000000000007439 73.0
SHD3_k127_1506660_0 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000003573 118.0
SHD3_k127_1506660_1 - - - - 0.0000000000000001078 80.0
SHD3_k127_1506660_2 Antibiotic biosynthesis monooxygenase - - - 0.000000000000001006 81.0
SHD3_k127_1506660_3 CsbD-like - - - 0.0000000006801 60.0
SHD3_k127_1508050_0 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000002302 252.0
SHD3_k127_151143_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1496.0
SHD3_k127_151143_1 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 587.0
SHD3_k127_1513771_0 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000009694 143.0
SHD3_k127_1516862_0 Carbon-nitrogen hydrolase K01501,K01502 - 3.5.5.1,3.5.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 366.0
SHD3_k127_1516862_1 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000006608 145.0
SHD3_k127_1516862_2 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000486 99.0
SHD3_k127_1518775_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 2.896e-267 847.0
SHD3_k127_1524973_0 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.0 1285.0
SHD3_k127_1524973_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.925e-269 843.0
SHD3_k127_1524973_10 succinate dehydrogenase K00241,K00247 - - 0.000000000000000000003634 97.0
SHD3_k127_1524973_11 succinate dehydrogenase activity K00242,K00246 - - 0.000000000000000001261 92.0
SHD3_k127_1524973_12 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000005139 57.0
SHD3_k127_1524973_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 556.0
SHD3_k127_1524973_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 439.0
SHD3_k127_1524973_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 414.0
SHD3_k127_1524973_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 381.0
SHD3_k127_1524973_6 pfam abc K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 352.0
SHD3_k127_1524973_7 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 312.0
SHD3_k127_1524973_8 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002674 271.0
SHD3_k127_1524973_9 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001393 268.0
SHD3_k127_1527599_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 6.787e-312 978.0
SHD3_k127_1527599_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 2.196e-217 685.0
SHD3_k127_1527599_11 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000006323 126.0
SHD3_k127_1527599_12 PQ loop repeat K15383 - - 0.00000000000000000000147 98.0
SHD3_k127_1527599_13 protein-glutamate methylesterase activity K00575,K03412,K03413,K07719 - 2.1.1.80,3.1.1.61,3.5.1.44 0.0000000000000000421 89.0
SHD3_k127_1527599_14 - - - - 0.0000000000000001945 82.0
SHD3_k127_1527599_15 Cytochrome c7 and related cytochrome c - - - 0.0000000000000002096 83.0
SHD3_k127_1527599_16 Modulates RecA activity K03565,K19002 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 0.000000000000001461 82.0
SHD3_k127_1527599_17 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.00008395 53.0
SHD3_k127_1527599_18 Glucose / Sorbosone dehydrogenase - - - 0.0009916 48.0
SHD3_k127_1527599_2 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 578.0
SHD3_k127_1527599_3 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 499.0
SHD3_k127_1527599_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 497.0
SHD3_k127_1527599_5 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 437.0
SHD3_k127_1527599_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001138 248.0
SHD3_k127_1527599_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000000002141 149.0
SHD3_k127_1527599_8 CHRD domain - - - 0.000000000000000000000000000000000004245 139.0
SHD3_k127_1527599_9 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000001431 130.0
SHD3_k127_1534364_0 PFAM Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000618 89.0
SHD3_k127_1534364_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00004129 48.0
SHD3_k127_1535245_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 361.0
SHD3_k127_1535245_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000007791 173.0
SHD3_k127_153794_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 403.0
SHD3_k127_153794_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 367.0
SHD3_k127_153794_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 319.0
SHD3_k127_153794_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 301.0
SHD3_k127_153794_4 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000003303 230.0
SHD3_k127_153794_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000001346 179.0
SHD3_k127_153794_6 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000005068 133.0
SHD3_k127_153794_7 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000004043 94.0
SHD3_k127_1542344_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 366.0
SHD3_k127_1542344_1 Phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000002584 163.0
SHD3_k127_1545351_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 4.357e-198 624.0
SHD3_k127_1545351_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 491.0
SHD3_k127_1545351_10 Universal stress protein family - - - 0.0000000000000000000000000000000000000005794 156.0
SHD3_k127_1545351_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.00000000000000000000000000000000000009092 153.0
SHD3_k127_1545351_12 proteolysis K03665 - - 0.000000000000000000000000000001638 126.0
SHD3_k127_1545351_13 - - - - 0.000002525 49.0
SHD3_k127_1545351_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 455.0
SHD3_k127_1545351_3 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 340.0
SHD3_k127_1545351_4 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000007251 261.0
SHD3_k127_1545351_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000006662 248.0
SHD3_k127_1545351_6 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002083 235.0
SHD3_k127_1545351_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001383 234.0
SHD3_k127_1545351_8 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000002017 236.0
SHD3_k127_1545351_9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000001513 174.0
SHD3_k127_1561019_0 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 571.0
SHD3_k127_1561019_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 292.0
SHD3_k127_1561019_2 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000003215 223.0
SHD3_k127_1561172_0 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000001404 164.0
SHD3_k127_1575308_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.94e-268 837.0
SHD3_k127_1575308_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.329e-211 664.0
SHD3_k127_1575308_10 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 332.0
SHD3_k127_1575308_11 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 318.0
SHD3_k127_1575308_12 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000134 261.0
SHD3_k127_1575308_13 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000002138 235.0
SHD3_k127_1575308_14 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000007374 209.0
SHD3_k127_1575308_15 retrograde transport, endosome to Golgi K07095 - - 0.00000000000000000000000000000000000000000000000000113 187.0
SHD3_k127_1575308_16 SURF4 family K15977 - - 0.000000000000000000000000000000000000000001048 160.0
SHD3_k127_1575308_17 phosphorelay signal transduction system - - - 0.00000000000000000000000002606 112.0
SHD3_k127_1575308_18 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.00000000000000001109 86.0
SHD3_k127_1575308_19 nucleotidyltransferase activity K07075 - - 0.00009176 48.0
SHD3_k127_1575308_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.55e-208 653.0
SHD3_k127_1575308_3 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 497.0
SHD3_k127_1575308_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 472.0
SHD3_k127_1575308_5 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 467.0
SHD3_k127_1575308_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 409.0
SHD3_k127_1575308_7 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 415.0
SHD3_k127_1575308_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 403.0
SHD3_k127_1575308_9 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 355.0
SHD3_k127_1576270_0 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 436.0
SHD3_k127_1576270_1 Amidohydrolase - - - 0.0000000000000000000000000000000002137 145.0
SHD3_k127_1576270_2 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.000000000001773 67.0
SHD3_k127_1582243_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.923e-237 745.0
SHD3_k127_1582243_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 441.0
SHD3_k127_1582243_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 337.0
SHD3_k127_1582243_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000004188 179.0
SHD3_k127_1582243_4 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000005987 177.0
SHD3_k127_1582243_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000003605 160.0
SHD3_k127_1582243_6 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000001479 145.0
SHD3_k127_1582243_7 peptidyl-tyrosine sulfation - - - 0.000000001437 71.0
SHD3_k127_1582836_0 domain, Protein K01186 - 3.2.1.18 0.0000000000000000000000000009993 124.0
SHD3_k127_1582836_1 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.00000000002953 72.0
SHD3_k127_1583150_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 575.0
SHD3_k127_1583150_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 575.0
SHD3_k127_1583150_10 metal-dependent enzyme K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 298.0
SHD3_k127_1583150_11 PFAM HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000524 268.0
SHD3_k127_1583150_12 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 267.0
SHD3_k127_1583150_13 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000007812 254.0
SHD3_k127_1583150_14 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000001577 235.0
SHD3_k127_1583150_15 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000003688 201.0
SHD3_k127_1583150_16 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000479 201.0
SHD3_k127_1583150_17 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000002168 197.0
SHD3_k127_1583150_18 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000007705 186.0
SHD3_k127_1583150_19 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000001226 184.0
SHD3_k127_1583150_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 580.0
SHD3_k127_1583150_20 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000008014 151.0
SHD3_k127_1583150_21 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000004883 152.0
SHD3_k127_1583150_22 phosphorelay signal transduction system - - - 0.0000000000000000000000000000267 121.0
SHD3_k127_1583150_23 Binds the 23S rRNA K02909 - - 0.00000000000000000000000002805 109.0
SHD3_k127_1583150_24 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000007775 96.0
SHD3_k127_1583150_26 PFAM Uncharacterised protein family UPF0150 - - - 0.0002689 46.0
SHD3_k127_1583150_3 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 559.0
SHD3_k127_1583150_4 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 560.0
SHD3_k127_1583150_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 511.0
SHD3_k127_1583150_6 Chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 425.0
SHD3_k127_1583150_7 response regulator K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 377.0
SHD3_k127_1583150_8 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 341.0
SHD3_k127_1583150_9 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 315.0
SHD3_k127_1593955_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 549.0
SHD3_k127_1593955_1 - - - - 0.000000006063 62.0
SHD3_k127_1596423_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 3.651e-203 638.0
SHD3_k127_1596423_1 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 366.0
SHD3_k127_1596423_2 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000002787 203.0
SHD3_k127_1596423_3 acetyltransferase - - - 0.000000000000000000000313 99.0
SHD3_k127_1596423_4 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000006367 93.0
SHD3_k127_1596423_5 PFAM ResB family protein K07399 - - 0.0000000000000000001416 91.0
SHD3_k127_1598004_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008993 267.0
SHD3_k127_1598004_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000004949 126.0
SHD3_k127_1603718_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 497.0
SHD3_k127_1603718_1 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000007499 103.0
SHD3_k127_1604635_0 L,D-transpeptidase catalytic domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 612.0
SHD3_k127_1604635_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 603.0
SHD3_k127_1604635_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 321.0
SHD3_k127_1604635_11 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 318.0
SHD3_k127_1604635_12 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002422 267.0
SHD3_k127_1604635_13 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000001938 185.0
SHD3_k127_1604635_14 Cytochrome c K16966,K17049,K17052 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000002267 169.0
SHD3_k127_1604635_15 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000001732 111.0
SHD3_k127_1604635_16 Alanine-zipper, major outer membrane lipoprotein - - - 0.0000000000000003164 82.0
SHD3_k127_1604635_2 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 503.0
SHD3_k127_1604635_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 477.0
SHD3_k127_1604635_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00220,K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 1.3.1.12,1.3.1.43,2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 441.0
SHD3_k127_1604635_5 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 435.0
SHD3_k127_1604635_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 433.0
SHD3_k127_1604635_7 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 432.0
SHD3_k127_1604635_8 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 414.0
SHD3_k127_1604635_9 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 352.0
SHD3_k127_1630533_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 377.0
SHD3_k127_1630533_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000306 130.0
SHD3_k127_1630533_2 response regulator, receiver - - - 0.00000000000000000000000000001691 134.0
SHD3_k127_1630721_0 Ftsk_gamma K03466 - - 5.615e-204 657.0
SHD3_k127_1630721_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.055e-200 640.0
SHD3_k127_1630721_10 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000002347 83.0
SHD3_k127_1630721_11 - - - - 0.000000000001256 81.0
SHD3_k127_1630721_12 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.0000000003503 66.0
SHD3_k127_1630721_13 Cobyrinic acid ac-diamide synthase K07321 - - 0.00001963 47.0
SHD3_k127_1630721_14 cheY-homologous receiver domain - - - 0.0002844 47.0
SHD3_k127_1630721_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 510.0
SHD3_k127_1630721_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 507.0
SHD3_k127_1630721_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 387.0
SHD3_k127_1630721_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 370.0
SHD3_k127_1630721_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004844 274.0
SHD3_k127_1630721_7 HD domain - - - 0.0000000000000000000000000000000000000000000001091 183.0
SHD3_k127_1630721_8 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000002674 145.0
SHD3_k127_1630721_9 domain, Protein K00703,K07082 - 2.4.1.21 0.0000000000000002133 84.0
SHD3_k127_1633525_0 - - - - 0.00009659 51.0
SHD3_k127_1641152_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1292.0
SHD3_k127_1641152_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5e-324 1004.0
SHD3_k127_1641152_10 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 367.0
SHD3_k127_1641152_11 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 307.0
SHD3_k127_1641152_12 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 295.0
SHD3_k127_1641152_13 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002166 244.0
SHD3_k127_1641152_14 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000001354 229.0
SHD3_k127_1641152_15 Peptidase S24-like K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000001156 209.0
SHD3_k127_1641152_16 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000005036 192.0
SHD3_k127_1641152_17 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000009336 164.0
SHD3_k127_1641152_18 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000006242 141.0
SHD3_k127_1641152_19 NUDIX hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000000005736 139.0
SHD3_k127_1641152_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 6.553e-311 976.0
SHD3_k127_1641152_20 AMP binding K09118,K13693 - 2.4.1.266 0.0000000000000000000000001796 116.0
SHD3_k127_1641152_21 Domain of unknown function (DUF4412) - - - 0.0000000000000000000001871 106.0
SHD3_k127_1641152_22 protein conserved in bacteria - - - 0.000000000000000002002 89.0
SHD3_k127_1641152_23 - - - - 0.0000000000000001374 82.0
SHD3_k127_1641152_24 NUDIX hydrolase - - - 0.0000000000000003587 82.0
SHD3_k127_1641152_25 - - - - 0.00000000008304 68.0
SHD3_k127_1641152_27 Two component transcriptional regulator, winged helix family K07667 - - 0.00004313 48.0
SHD3_k127_1641152_28 toxin-antitoxin pair type II binding - - - 0.00009889 48.0
SHD3_k127_1641152_29 nucleic acid-binding protein contains PIN domain - - - 0.0005322 49.0
SHD3_k127_1641152_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 3.763e-261 818.0
SHD3_k127_1641152_30 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0009807 51.0
SHD3_k127_1641152_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 532.0
SHD3_k127_1641152_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 494.0
SHD3_k127_1641152_6 - K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 442.0
SHD3_k127_1641152_7 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 428.0
SHD3_k127_1641152_8 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 396.0
SHD3_k127_1641152_9 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 365.0
SHD3_k127_164159_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1429.0
SHD3_k127_164159_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 530.0
SHD3_k127_164159_10 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000002535 207.0
SHD3_k127_164159_11 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.00000000000000000000000000000000000000001604 162.0
SHD3_k127_164159_12 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000008341 126.0
SHD3_k127_164159_13 cheY-homologous receiver domain - - - 0.000000000000000000000794 99.0
SHD3_k127_164159_14 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000007473 98.0
SHD3_k127_164159_15 YbbR-like protein - - - 0.00001661 56.0
SHD3_k127_164159_16 Putative serine esterase (DUF676) - - - 0.0006232 49.0
SHD3_k127_164159_2 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 407.0
SHD3_k127_164159_3 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 389.0
SHD3_k127_164159_4 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 357.0
SHD3_k127_164159_5 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 351.0
SHD3_k127_164159_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 323.0
SHD3_k127_164159_7 PFAM ATP-binding region, ATPase-like histidine kinase A-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 319.0
SHD3_k127_164159_8 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007351 254.0
SHD3_k127_164159_9 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000002154 199.0
SHD3_k127_1642814_0 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 495.0
SHD3_k127_1651746_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 496.0
SHD3_k127_1654496_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 440.0
SHD3_k127_1659196_0 Catalyzes the synthesis of activated sulfate K00860,K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 303.0
SHD3_k127_1659196_1 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000000000000000007596 166.0
SHD3_k127_1659196_2 ABC-2 type transporter K09690,K09692 - - 0.000000000000000000000000000000000000000641 151.0
SHD3_k127_1686907_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1013.0
SHD3_k127_1686907_1 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 402.0
SHD3_k127_1686907_2 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000000000000000006405 154.0
SHD3_k127_1686907_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000001805 108.0
SHD3_k127_1686907_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K16886 - - 0.0000000006119 60.0
SHD3_k127_1687271_0 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 575.0
SHD3_k127_1687271_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 546.0
SHD3_k127_1687271_10 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000001836 194.0
SHD3_k127_1687271_11 Thiamine-binding protein - - - 0.0000000000000000000000000000000006061 133.0
SHD3_k127_1687271_12 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000000000000000000000000003425 126.0
SHD3_k127_1687271_13 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000000003388 109.0
SHD3_k127_1687271_14 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000002559 87.0
SHD3_k127_1687271_15 Protein of unknown function (DUF1566) - - - 0.0000000002202 66.0
SHD3_k127_1687271_16 Tetratricopeptide repeat K07452 - - 0.000000004842 66.0
SHD3_k127_1687271_2 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 387.0
SHD3_k127_1687271_3 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 372.0
SHD3_k127_1687271_4 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004304 294.0
SHD3_k127_1687271_5 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002482 262.0
SHD3_k127_1687271_6 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000001016 235.0
SHD3_k127_1687271_7 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000003759 220.0
SHD3_k127_1687271_8 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000259 226.0
SHD3_k127_1687271_9 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000004983 198.0
SHD3_k127_1694416_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 395.0
SHD3_k127_1694416_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000005882 132.0
SHD3_k127_1694416_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000005988 67.0
SHD3_k127_1694416_3 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.0003696 50.0
SHD3_k127_1702093_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 4.292e-196 616.0
SHD3_k127_1702093_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 609.0
SHD3_k127_1702093_10 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000001469 174.0
SHD3_k127_1702093_11 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000003767 173.0
SHD3_k127_1702093_12 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000002555 124.0
SHD3_k127_1702093_13 Belongs to the UPF0296 family K09777 - - 0.00000000000000000000000002723 111.0
SHD3_k127_1702093_14 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000608 91.0
SHD3_k127_1702093_15 belongs to the thioredoxin family K14949,K20543 - 2.7.11.1 0.0000000000000000001192 101.0
SHD3_k127_1702093_16 Roadblock/LC7 domain - - - 0.0000000000000000002808 92.0
SHD3_k127_1702093_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 496.0
SHD3_k127_1702093_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 384.0
SHD3_k127_1702093_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 312.0
SHD3_k127_1702093_5 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000002562 274.0
SHD3_k127_1702093_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000001628 245.0
SHD3_k127_1702093_7 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000001595 219.0
SHD3_k127_1702093_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000009917 214.0
SHD3_k127_1702093_9 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000001373 171.0
SHD3_k127_1711399_0 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000007104 123.0
SHD3_k127_1711399_1 PEGA domain - - - 0.00000000000000000006977 97.0
SHD3_k127_1711399_2 Protein of unknown function (DUF2945) - - - 0.000000001756 60.0
SHD3_k127_1726217_0 reverse transcriptase K00986,K15342 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 371.0
SHD3_k127_1731655_0 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000005556 117.0
SHD3_k127_1731655_1 - - - - 0.0000000001826 66.0
SHD3_k127_1731655_2 Domain of unknown function (DUF333) K09712 - - 0.000009178 50.0
SHD3_k127_1732374_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.326e-203 642.0
SHD3_k127_1732374_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 486.0
SHD3_k127_1732374_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 328.0
SHD3_k127_1732374_3 glutaminyl-tRNA K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000001117 237.0
SHD3_k127_1732374_4 Domain of unknown function (DUF4115) - - - 0.00000000000000002898 90.0
SHD3_k127_1734562_0 Uncharacterised protein family (UPF0182) K09118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 364.0
SHD3_k127_1741491_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 2.131e-218 692.0
SHD3_k127_1741491_1 FAD dependent oxidoreductase K16885 - - 0.0000007917 52.0
SHD3_k127_175416_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.186e-198 624.0
SHD3_k127_175416_1 ABC transporter K02021,K06147,K11085 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 501.0
SHD3_k127_175416_10 Transcriptional regulator - - - 0.000000000000000000000000000000004169 136.0
SHD3_k127_175416_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000009998 126.0
SHD3_k127_175416_12 - - - - 0.0000000000000000006593 89.0
SHD3_k127_175416_13 Glycosyl transferase family 2 - - - 0.00000000000005072 72.0
SHD3_k127_175416_14 O-Antigen ligase K02847 - - 0.0000000000001869 82.0
SHD3_k127_175416_15 CYTH K05873 - 4.6.1.1 0.000000000002791 74.0
SHD3_k127_175416_16 - - - - 0.0000000006385 63.0
SHD3_k127_175416_17 PFAM Rhodanese domain protein - - - 0.00000001873 62.0
SHD3_k127_175416_2 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 359.0
SHD3_k127_175416_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 312.0
SHD3_k127_175416_4 transferase activity, transferring glycosyl groups K13500 - 2.4.1.175,2.4.1.226 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 299.0
SHD3_k127_175416_5 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001685 285.0
SHD3_k127_175416_6 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000003854 241.0
SHD3_k127_175416_7 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000008292 197.0
SHD3_k127_175416_8 AMP binding - - - 0.00000000000000000000000000000000000000004116 157.0
SHD3_k127_175416_9 AMP binding - - - 0.0000000000000000000000000000000000000002176 161.0
SHD3_k127_1767576_0 metallopeptidase activity - - - 0.00000000000000000000000000000000001282 152.0
SHD3_k127_1767576_1 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.000000000000000000000001012 113.0
SHD3_k127_1767576_2 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.00000000000000000002147 105.0
SHD3_k127_1780877_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 610.0
SHD3_k127_1780877_1 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000003878 140.0
SHD3_k127_1780877_2 protein-glutamate methylesterase K00575,K13924 - 2.1.1.80,3.1.1.61 0.0000002827 53.0
SHD3_k127_179018_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.229e-295 915.0
SHD3_k127_179018_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.103e-279 882.0
SHD3_k127_179018_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 438.0
SHD3_k127_179018_11 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K11384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 443.0
SHD3_k127_179018_12 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 395.0
SHD3_k127_179018_13 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 370.0
SHD3_k127_179018_14 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 367.0
SHD3_k127_179018_15 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 355.0
SHD3_k127_179018_16 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 315.0
SHD3_k127_179018_17 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 313.0
SHD3_k127_179018_18 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 305.0
SHD3_k127_179018_19 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 287.0
SHD3_k127_179018_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.536e-262 820.0
SHD3_k127_179018_20 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000469 258.0
SHD3_k127_179018_21 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001215 260.0
SHD3_k127_179018_22 Chemotaxis sensory transducer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002083 271.0
SHD3_k127_179018_23 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002939 247.0
SHD3_k127_179018_24 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000005578 207.0
SHD3_k127_179018_25 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000001737 187.0
SHD3_k127_179018_26 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000008516 192.0
SHD3_k127_179018_27 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.00000000000000000000000000000000000000000003027 170.0
SHD3_k127_179018_28 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000003311 159.0
SHD3_k127_179018_29 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000001178 156.0
SHD3_k127_179018_3 Glycosyl hydrolase family 57 - - - 1.07e-237 756.0
SHD3_k127_179018_30 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000000006251 149.0
SHD3_k127_179018_31 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000006955 146.0
SHD3_k127_179018_32 - - - - 0.000000000000000000000000000000003158 145.0
SHD3_k127_179018_33 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000005825 134.0
SHD3_k127_179018_34 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000001083 114.0
SHD3_k127_179018_35 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000007895 109.0
SHD3_k127_179018_36 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000003651 93.0
SHD3_k127_179018_37 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000002417 88.0
SHD3_k127_179018_38 Sporulation and spore germination - - - 0.000000000000007746 82.0
SHD3_k127_179018_39 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000001639 78.0
SHD3_k127_179018_4 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 1.354e-228 730.0
SHD3_k127_179018_40 cell cycle K05589,K12065,K13052 - - 0.00000000000001849 77.0
SHD3_k127_179018_41 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000008578 75.0
SHD3_k127_179018_43 STAS domain - - - 0.0000008003 57.0
SHD3_k127_179018_44 Pfam:Cache_1 K03406 - - 0.00001436 49.0
SHD3_k127_179018_5 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 3.456e-214 676.0
SHD3_k127_179018_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 596.0
SHD3_k127_179018_7 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 542.0
SHD3_k127_179018_8 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008129 539.0
SHD3_k127_179018_9 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 485.0
SHD3_k127_180923_0 - - - - 0.000000000000000000000000002319 113.0
SHD3_k127_180923_1 - - - - 0.0000000000000000000001826 98.0
SHD3_k127_180923_2 - - - - 0.0000000000002427 71.0
SHD3_k127_1818625_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000003506 136.0
SHD3_k127_1818625_1 - - - - 0.000000000000000001362 88.0
SHD3_k127_1818627_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000002059 139.0
SHD3_k127_1818627_1 - - - - 0.000000000000000002567 87.0
SHD3_k127_1827106_0 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000000000000000209 198.0
SHD3_k127_183165_0 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000002104 213.0
SHD3_k127_183165_1 ABC transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000007072 217.0
SHD3_k127_183165_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000001636 208.0
SHD3_k127_183165_3 Putative capsular polysaccharide synthesis protein - - - 0.000000000000000000000000000137 126.0
SHD3_k127_1833080_0 Class III cytochrome C family - - - 0.0000000009183 65.0
SHD3_k127_1843172_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 587.0
SHD3_k127_1843172_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 515.0
SHD3_k127_1843172_10 Universal stress protein family K07090 - - 0.00000000000000000000000000001122 124.0
SHD3_k127_1843172_12 - - - - 0.000000000000000001705 88.0
SHD3_k127_1843172_2 protein secretion K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 534.0
SHD3_k127_1843172_3 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 462.0
SHD3_k127_1843172_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 476.0
SHD3_k127_1843172_5 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 409.0
SHD3_k127_1843172_6 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000001091 219.0
SHD3_k127_1843172_7 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000005097 221.0
SHD3_k127_1843172_8 - - - - 0.000000000000000000000000000000000000000000000000005013 184.0
SHD3_k127_1843172_9 UTRA K03710 - - 0.0000000000000000000000000000002419 132.0
SHD3_k127_1853741_0 PFAM Mannosyl oligosaccharide glucosidase - - - 0.0 1137.0
SHD3_k127_1853741_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000003241 231.0
SHD3_k127_1853741_2 curli production assembly transport component CsgG - - - 0.00000000000008193 71.0
SHD3_k127_185572_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.227e-246 769.0
SHD3_k127_185572_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.378e-237 752.0
SHD3_k127_185572_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.769e-232 725.0
SHD3_k127_185572_3 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 313.0
SHD3_k127_185572_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 295.0
SHD3_k127_185572_5 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000001106 95.0
SHD3_k127_191255_0 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001899 289.0
SHD3_k127_191255_1 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000001951 243.0
SHD3_k127_1945237_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 5.683e-227 707.0
SHD3_k127_1945237_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 608.0
SHD3_k127_1945237_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 487.0
SHD3_k127_1945237_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008726 336.0
SHD3_k127_1945237_4 histidine kinase, HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000007144 219.0
SHD3_k127_1945237_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000003776 198.0
SHD3_k127_1945237_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000002113 124.0
SHD3_k127_1945237_7 - - - - 0.0000000000000000001206 99.0
SHD3_k127_1945237_8 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000006051 79.0
SHD3_k127_195764_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 379.0
SHD3_k127_2009044_0 amino acid K14052 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008324,GO:0008519,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015101,GO:0015203,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015489,GO:0015672,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0033554,GO:0034220,GO:0034641,GO:0040011,GO:0042402,GO:0044106,GO:0044237,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051234,GO:0051674,GO:0051716,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072488,GO:0097164,GO:0098655,GO:0098660,GO:0098662,GO:1901564,GO:1901565,GO:1901575,GO:1902047,GO:1902600 - 9.043e-281 874.0
SHD3_k127_2009044_1 TIGRFAM Ammonium transporter K03320 - - 1.131e-238 749.0
SHD3_k127_2009044_2 Serine/threonine phosphatases, family 2C, catalytic domain - - - 6.549e-197 630.0
SHD3_k127_2009044_3 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 502.0
SHD3_k127_2009044_4 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000008084 166.0
SHD3_k127_2009044_5 - K09771 - - 0.000000000000000000000000000000000000000001289 158.0
SHD3_k127_2009044_6 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000004128 104.0
SHD3_k127_203064_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.853e-254 789.0
SHD3_k127_203064_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.133e-242 757.0
SHD3_k127_203064_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.915e-237 758.0
SHD3_k127_203064_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 330.0
SHD3_k127_203064_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000001625 159.0
SHD3_k127_203064_5 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000004427 155.0
SHD3_k127_203064_6 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000001686 110.0
SHD3_k127_204289_0 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 4.195e-224 706.0
SHD3_k127_204289_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 1.057e-203 636.0
SHD3_k127_204289_10 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000001629 141.0
SHD3_k127_204289_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000002121 80.0
SHD3_k127_204289_12 Transposase K07483 - - 0.0000000813 59.0
SHD3_k127_204289_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 592.0
SHD3_k127_204289_3 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 587.0
SHD3_k127_204289_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 597.0
SHD3_k127_204289_5 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 477.0
SHD3_k127_204289_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 369.0
SHD3_k127_204289_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000275 254.0
SHD3_k127_204289_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004151 233.0
SHD3_k127_204289_9 Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000005529 139.0
SHD3_k127_205806_0 - - - - 0.00000000004201 71.0
SHD3_k127_205806_1 Excisionase - - - 0.0003415 46.0
SHD3_k127_2074311_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.726e-222 706.0
SHD3_k127_2074311_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 520.0
SHD3_k127_2074311_10 PFAM Amidohydrolase 2 - - - 0.00000000000000000000000000000000002937 148.0
SHD3_k127_2074311_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000001083 134.0
SHD3_k127_2074311_12 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000000000007261 131.0
SHD3_k127_2074311_13 Protein required for attachment to host cells - - - 0.000000000000000000000000008666 116.0
SHD3_k127_2074311_14 Autoinducer binding domain K20334 - - 0.000000000000000615 80.0
SHD3_k127_2074311_15 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000072 68.0
SHD3_k127_2074311_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 471.0
SHD3_k127_2074311_3 TonB dependent receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 479.0
SHD3_k127_2074311_4 response regulator receiver K02481,K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 398.0
SHD3_k127_2074311_5 radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 385.0
SHD3_k127_2074311_6 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 388.0
SHD3_k127_2074311_7 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001711 262.0
SHD3_k127_2074311_8 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000001773 211.0
SHD3_k127_2074311_9 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000285 201.0
SHD3_k127_207605_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 351.0
SHD3_k127_207605_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 336.0
SHD3_k127_207605_10 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.00000000000000000000000001474 113.0
SHD3_k127_207605_11 Putative regulatory protein - - - 0.00000000000000000000004124 101.0
SHD3_k127_207605_12 - - - - 0.0000000000000002588 81.0
SHD3_k127_207605_13 PFAM Rubrerythrin - - - 0.000000000002635 73.0
SHD3_k127_207605_2 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 307.0
SHD3_k127_207605_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 309.0
SHD3_k127_207605_4 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000002602 229.0
SHD3_k127_207605_5 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000004483 228.0
SHD3_k127_207605_6 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000000000000292 156.0
SHD3_k127_207605_7 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0000000000000000000000000000001954 123.0
SHD3_k127_207605_8 PFAM CBS domain - - - 0.0000000000000000000000000000007063 130.0
SHD3_k127_207605_9 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000008787 126.0
SHD3_k127_208884_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 587.0
SHD3_k127_208884_1 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 369.0
SHD3_k127_208884_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 320.0
SHD3_k127_208884_3 Branched-chain amino acid ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000134 277.0
SHD3_k127_208884_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003421 263.0
SHD3_k127_208884_5 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000001119 158.0
SHD3_k127_2118890_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 459.0
SHD3_k127_2118890_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000006395 222.0
SHD3_k127_2118890_2 Belongs to the 'phage' integrase family - - - 0.00000000000004565 78.0
SHD3_k127_2119741_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004897 239.0
SHD3_k127_2119741_2 Transposase IS200 like - - - 0.0000000000000000005251 89.0
SHD3_k127_2128503_0 PFAM integrase K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 308.0
SHD3_k127_2128503_1 Transposase K07483 - - 0.00000000000000009077 83.0
SHD3_k127_2155555_0 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 1.762e-222 694.0
SHD3_k127_215605_0 non supervised orthologous group - - - 0.00000000000002166 73.0
SHD3_k127_215605_1 - - - - 0.00000000000004256 73.0
SHD3_k127_215605_2 - - - - 0.000000000003528 67.0
SHD3_k127_2156233_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1711.0
SHD3_k127_2156233_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 337.0
SHD3_k127_2156233_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001661 259.0
SHD3_k127_2156233_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000001011 212.0
SHD3_k127_2156233_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000004311 197.0
SHD3_k127_2156233_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000000000000008428 139.0
SHD3_k127_2156233_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000005711 143.0
SHD3_k127_2156233_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000002461 81.0
SHD3_k127_2156233_8 Ribosomal protein L33 K02913 - - 0.0000000000002434 72.0
SHD3_k127_2156233_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000005997 70.0
SHD3_k127_2175290_0 Transposase DDE domain K07487 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008135 256.0
SHD3_k127_217907_1 - - - - 0.0000000000000001538 80.0
SHD3_k127_217907_2 - - - - 0.00001963 47.0
SHD3_k127_2182800_0 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008465 295.0
SHD3_k127_2186061_0 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 508.0
SHD3_k127_2188465_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 357.0
SHD3_k127_2188465_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 302.0
SHD3_k127_2188465_2 TraB family K09973 - - 0.0000000000000000000000000000001377 128.0
SHD3_k127_2190109_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 510.0
SHD3_k127_2190109_1 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000000000000000005681 224.0
SHD3_k127_2199370_0 Acyl transferase domain - - - 0.0 1680.0
SHD3_k127_2204943_0 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 593.0
SHD3_k127_2204943_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001775 276.0
SHD3_k127_2204997_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 308.0
SHD3_k127_2204997_1 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000000000000000004505 180.0
SHD3_k127_2204997_2 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000008204 134.0
SHD3_k127_2221626_0 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 392.0
SHD3_k127_2221626_1 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 299.0
SHD3_k127_2221626_2 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003094 259.0
SHD3_k127_2221626_3 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000000004668 138.0
SHD3_k127_2221626_5 TPM domain - - - 0.00000000002378 66.0
SHD3_k127_2229417_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 389.0
SHD3_k127_2229417_1 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 332.0
SHD3_k127_2229417_10 Belongs to the universal stress protein A family - - - 0.000000000000000000000000004146 117.0
SHD3_k127_2229417_11 Transglycosylase SLT domain - - - 0.00000000008827 71.0
SHD3_k127_2229417_12 Protein of unknown function (DUF2934) - - - 0.0000006516 51.0
SHD3_k127_2229417_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006864 258.0
SHD3_k127_2229417_3 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001153 244.0
SHD3_k127_2229417_5 ATPase (AAA superfamily) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000005877 244.0
SHD3_k127_2229417_6 ISXO2-like transposase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000476 235.0
SHD3_k127_2229417_7 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000001241 229.0
SHD3_k127_2229417_8 PFAM aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000591 171.0
SHD3_k127_2229417_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000001977 147.0
SHD3_k127_2231766_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 474.0
SHD3_k127_2231766_1 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 412.0
SHD3_k127_2231766_11 Belongs to the 'phage' integrase family - - - 0.00000000000000003765 85.0
SHD3_k127_2231766_12 Universal stress protein family - - - 0.0000000000000008947 89.0
SHD3_k127_2231766_13 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000003443 79.0
SHD3_k127_2231766_14 Putative regulatory protein - - - 0.0000005352 53.0
SHD3_k127_2231766_15 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0004742 44.0
SHD3_k127_2231766_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003124 267.0
SHD3_k127_2231766_3 dUTP biosynthetic process K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000004434 250.0
SHD3_k127_2231766_4 tRNA modification K06968 - 2.1.1.186 0.000000000000000000000000000000000000000000000000000000000000000000005677 238.0
SHD3_k127_2231766_5 Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000007483 178.0
SHD3_k127_2231766_6 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000009114 155.0
SHD3_k127_2231766_7 GYD domain - - - 0.00000000000000000000000000000000000008956 143.0
SHD3_k127_2231766_8 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.00000000000000000000005115 106.0
SHD3_k127_2231766_9 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000009645 101.0
SHD3_k127_2243858_0 PFAM ferredoxin-dependent glutamate synthase - - - 1.035e-288 893.0
SHD3_k127_2243858_1 Conserved region in glutamate synthase - - - 1.013e-272 846.0
SHD3_k127_2243858_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 394.0
SHD3_k127_2243858_3 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 388.0
SHD3_k127_2243858_4 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000000000000000000005355 183.0
SHD3_k127_2245605_0 Reverse transcriptase K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 593.0
SHD3_k127_2245605_2 - - - - 0.00000006963 55.0
SHD3_k127_2245605_3 General secretory system II protein E domain protein - - - 0.00001587 49.0
SHD3_k127_2245894_0 HTH-like domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 295.0
SHD3_k127_2245894_1 transposase activity K07483 - - 0.0000000000009162 72.0
SHD3_k127_2252114_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1165.0
SHD3_k127_2252114_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 460.0
SHD3_k127_2252114_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 353.0
SHD3_k127_2252114_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000001385 231.0
SHD3_k127_2252114_4 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000006614 190.0
SHD3_k127_2252114_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000002444 173.0
SHD3_k127_2252114_6 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000006442 104.0
SHD3_k127_2252114_7 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0008282 42.0
SHD3_k127_2257722_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 389.0
SHD3_k127_2257722_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 391.0
SHD3_k127_2257722_2 Hydrogenase (NiFe) small subunit HydA K05927,K06282,K18008 - 1.12.2.1,1.12.5.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000227 278.0
SHD3_k127_2257722_3 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.00000000000000000000000000000000005252 133.0
SHD3_k127_2259222_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.0000000000000000000000000000000000006336 143.0
SHD3_k127_2259222_1 PFAM Class III cytochrome C family - - - 0.0000000000000000000000002371 109.0
SHD3_k127_2269935_0 Sigma-54 interaction domain - - - 1.087e-241 758.0
SHD3_k127_2269935_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 408.0
SHD3_k127_2269935_2 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 353.0
SHD3_k127_2269935_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 374.0
SHD3_k127_2269935_4 FtsX-like permease family K02004 - - 0.000000000000000000000008626 102.0
SHD3_k127_22729_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 309.0
SHD3_k127_22729_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001438 267.0
SHD3_k127_22729_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001301 256.0
SHD3_k127_22729_3 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000008825 237.0
SHD3_k127_22729_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003346 222.0
SHD3_k127_2274053_0 PFAM Sulfotransferase domain - - - 0.00000000002806 72.0
SHD3_k127_2279822_0 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 347.0
SHD3_k127_2279822_1 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.000000001429 59.0
SHD3_k127_2281646_0 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.000000000000000000000000000000000000002697 153.0
SHD3_k127_2281646_1 manually curated - - - 0.000000000001409 69.0
SHD3_k127_2281646_2 spectrin binding K21440 - - 0.000000144 64.0
SHD3_k127_2285020_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 3.965e-225 715.0
SHD3_k127_2285020_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 418.0
SHD3_k127_2285020_10 PFAM PBS lyase HEAT-like repeat - - - 0.000000000000000000361 93.0
SHD3_k127_2285020_11 OsmC-like protein - - - 0.00000000000000003342 88.0
SHD3_k127_2285020_12 - - - - 0.000000000000008867 78.0
SHD3_k127_2285020_13 Arylsulfotransferase (ASST) - - - 0.00000000000002944 85.0
SHD3_k127_2285020_14 PFAM Nitrate reductase gamma subunit - - - 0.0000000004883 70.0
SHD3_k127_2285020_15 Protein of unknown function (DUF2934) - - - 0.000002697 53.0
SHD3_k127_2285020_2 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 373.0
SHD3_k127_2285020_3 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 319.0
SHD3_k127_2285020_4 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 329.0
SHD3_k127_2285020_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 314.0
SHD3_k127_2285020_6 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000004818 234.0
SHD3_k127_2285020_7 TIGRFAM iron-sulfur cluster binding protein - - - 0.00000000000000000000000000000000000000000000009684 175.0
SHD3_k127_2285020_8 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000006709 154.0
SHD3_k127_2285020_9 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000002926 111.0
SHD3_k127_2294592_0 - - - - 0.0000000000000000000000000000000000000001696 151.0
SHD3_k127_2294592_5 ORF located using Blastx - - - 0.0001496 44.0
SHD3_k127_2297556_0 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 465.0
SHD3_k127_2297556_1 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 372.0
SHD3_k127_2297556_2 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 374.0
SHD3_k127_2297556_3 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 336.0
SHD3_k127_2297556_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000001335 81.0
SHD3_k127_2297666_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 581.0
SHD3_k127_2297666_1 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 337.0
SHD3_k127_2297666_2 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 303.0
SHD3_k127_2297666_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005215 257.0
SHD3_k127_2297666_4 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000000000000003091 204.0
SHD3_k127_2297666_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000008644 199.0
SHD3_k127_2297666_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000003008 174.0
SHD3_k127_2297666_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000003239 174.0
SHD3_k127_2297666_8 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000004532 167.0
SHD3_k127_2299702_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 546.0
SHD3_k127_2312623_0 cobalamin binding protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000006517 209.0
SHD3_k127_2312623_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000001698 136.0
SHD3_k127_2312623_2 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000005197 55.0
SHD3_k127_2314793_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 331.0
SHD3_k127_2315626_0 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000002374 178.0
SHD3_k127_2315749_0 phosphorylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 362.0
SHD3_k127_2315749_1 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 329.0
SHD3_k127_2320262_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.445e-265 834.0
SHD3_k127_2320262_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 511.0
SHD3_k127_2320262_10 Uncharacterized conserved protein (DUF2304) - - - 0.00000000008566 67.0
SHD3_k127_2320262_11 - - - - 0.0000001297 59.0
SHD3_k127_2320262_2 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 447.0
SHD3_k127_2320262_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 338.0
SHD3_k127_2320262_4 Bacterial type II and III secretion system protein K02453,K03219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007532 303.0
SHD3_k127_2320262_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000001317 229.0
SHD3_k127_2320262_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000001016 218.0
SHD3_k127_2320262_7 group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000005149 215.0
SHD3_k127_2320262_8 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000304 209.0
SHD3_k127_2320262_9 - - - - 0.0000000000000000000001752 112.0
SHD3_k127_2335948_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 555.0
SHD3_k127_2335948_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 559.0
SHD3_k127_2335948_10 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000000002205 104.0
SHD3_k127_2335948_11 Protein of unknown function (DUF2892) - - - 0.000000000006471 72.0
SHD3_k127_2335948_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 494.0
SHD3_k127_2335948_3 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 493.0
SHD3_k127_2335948_4 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 369.0
SHD3_k127_2335948_5 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000007119 228.0
SHD3_k127_2335948_6 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000001477 224.0
SHD3_k127_2335948_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000002562 124.0
SHD3_k127_2335948_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000005615 114.0
SHD3_k127_2335962_0 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 383.0
SHD3_k127_2335962_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 350.0
SHD3_k127_2335962_2 Protein of unknown function (DUF1571) - - - 0.000000000000000000000000000000000000000000000000008243 188.0
SHD3_k127_2335962_4 Dual specificity phosphatase, catalytic domain - - - 0.000000001964 59.0
SHD3_k127_2351817_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1192.0
SHD3_k127_2351817_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1131.0
SHD3_k127_2351817_10 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 402.0
SHD3_k127_2351817_11 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 394.0
SHD3_k127_2351817_12 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 376.0
SHD3_k127_2351817_13 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 374.0
SHD3_k127_2351817_14 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 365.0
SHD3_k127_2351817_15 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 349.0
SHD3_k127_2351817_16 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 347.0
SHD3_k127_2351817_17 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 332.0
SHD3_k127_2351817_18 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 336.0
SHD3_k127_2351817_19 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 313.0
SHD3_k127_2351817_2 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1097.0
SHD3_k127_2351817_20 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 296.0
SHD3_k127_2351817_21 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 287.0
SHD3_k127_2351817_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003817 277.0
SHD3_k127_2351817_23 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
SHD3_k127_2351817_24 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006738 269.0
SHD3_k127_2351817_25 histidine kinase, HAMP K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000005637 248.0
SHD3_k127_2351817_26 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000008455 236.0
SHD3_k127_2351817_27 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000001206 236.0
SHD3_k127_2351817_28 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000001069 229.0
SHD3_k127_2351817_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1079.0
SHD3_k127_2351817_30 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000187 198.0
SHD3_k127_2351817_31 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000002401 208.0
SHD3_k127_2351817_32 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000008656 187.0
SHD3_k127_2351817_33 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000005203 186.0
SHD3_k127_2351817_34 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000000000000000000000002816 180.0
SHD3_k127_2351817_35 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000063 185.0
SHD3_k127_2351817_36 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000000005267 177.0
SHD3_k127_2351817_37 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000002916 169.0
SHD3_k127_2351817_38 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000003575 154.0
SHD3_k127_2351817_39 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000002548 156.0
SHD3_k127_2351817_4 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 2.314e-254 796.0
SHD3_k127_2351817_40 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000004057 148.0
SHD3_k127_2351817_41 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000007108 150.0
SHD3_k127_2351817_42 Thioredoxin-like - - - 0.00000000000000000000000000000000001142 141.0
SHD3_k127_2351817_43 cell redox homeostasis K02199 - - 0.000000000000000000000000000000006903 134.0
SHD3_k127_2351817_44 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000001135 128.0
SHD3_k127_2351817_45 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000551 125.0
SHD3_k127_2351817_46 Polymer-forming cytoskeletal - - - 0.000000000000000000000000009869 113.0
SHD3_k127_2351817_47 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000002715 111.0
SHD3_k127_2351817_48 Poly A polymerase head domain K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.00000000000000000000001139 114.0
SHD3_k127_2351817_49 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000008716 100.0
SHD3_k127_2351817_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.823e-231 727.0
SHD3_k127_2351817_50 AI-2E family transporter - - - 0.000000000000000151 82.0
SHD3_k127_2351817_52 protein secretion K03116,K03117 - - 0.000000000001839 70.0
SHD3_k127_2351817_53 COG2200 FOG EAL domain K20963 - 3.1.4.52 0.000000002317 66.0
SHD3_k127_2351817_54 - - - - 0.00000886 48.0
SHD3_k127_2351817_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 589.0
SHD3_k127_2351817_7 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 514.0
SHD3_k127_2351817_8 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 509.0
SHD3_k127_2351817_9 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 416.0
SHD3_k127_2367904_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 5.317e-277 860.0
SHD3_k127_2367904_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 3.183e-215 677.0
SHD3_k127_2367904_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 516.0
SHD3_k127_2367904_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 360.0
SHD3_k127_2367904_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000005447 211.0
SHD3_k127_2367904_5 Protein of unknown function (DUF1456) - - - 0.0000000000000000003026 87.0
SHD3_k127_2367904_6 - - - - 0.0005096 49.0
SHD3_k127_2370045_0 PFAM Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 396.0
SHD3_k127_2370045_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K09459 - 4.1.1.82 0.0000000000000000000000000000000000001424 147.0
SHD3_k127_2370045_2 Addiction module antidote protein, HigA K21498 - - 0.000000000000000000000000000000000007241 138.0
SHD3_k127_2371767_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.692e-236 739.0
SHD3_k127_2371767_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 580.0
SHD3_k127_2371767_2 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 526.0
SHD3_k127_2371767_3 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 524.0
SHD3_k127_2371767_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 461.0
SHD3_k127_2371767_5 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000584 196.0
SHD3_k127_2371767_6 ThiS family K03636 - - 0.00000000000000000000000000000000113 132.0
SHD3_k127_2371767_7 NIL - - - 0.000000000000000000000000007012 113.0
SHD3_k127_2371767_8 PFAM response regulator receiver - - - 0.0000004302 60.0
SHD3_k127_2372570_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 511.0
SHD3_k127_237954_0 - - - - 0.000000000000002068 82.0
SHD3_k127_2387238_0 response to heat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 549.0
SHD3_k127_2387238_1 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 389.0
SHD3_k127_2387238_2 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000005629 210.0
SHD3_k127_2387238_3 AMP binding K03499,K06149 - - 0.0000000000000000000000000000000000004194 144.0
SHD3_k127_2387238_4 membrane transporter protein K07090 - - 0.0000000000000000000000000001076 120.0
SHD3_k127_2395369_0 Acyl transferase domain - - - 7.386e-242 762.0
SHD3_k127_239993_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1207.0
SHD3_k127_239993_1 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002944 269.0
SHD3_k127_239993_2 S4 domain K14761 - - 0.000000000000000000003135 95.0
SHD3_k127_239993_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000001512 91.0
SHD3_k127_240456_0 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003891 271.0
SHD3_k127_240456_1 SMART ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001069 278.0
SHD3_k127_240456_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000004927 212.0
SHD3_k127_240456_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000008102 214.0
SHD3_k127_240456_4 cytochrome - - - 0.000000005712 57.0
SHD3_k127_240456_5 PilZ domain - - - 0.0000009138 59.0
SHD3_k127_2411957_0 membrane K08978 - - 0.0000000000000000000000000000000000000000000000000000000000003487 214.0
SHD3_k127_2411957_1 transposase activity - - - 0.0000000000000000000000000000000000000000000000101 187.0
SHD3_k127_2414088_0 Heat shock 70 kDa protein K04043 - - 0.0 1019.0
SHD3_k127_2414088_1 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 492.0
SHD3_k127_2414088_10 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 291.0
SHD3_k127_2414088_11 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001438 252.0
SHD3_k127_2414088_12 SEC-C motif K09858 - - 0.00000000000000000000000000000000000000000000000000000000000003817 218.0
SHD3_k127_2414088_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000004926 218.0
SHD3_k127_2414088_14 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000008367 183.0
SHD3_k127_2414088_15 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000002737 151.0
SHD3_k127_2414088_16 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000002933 72.0
SHD3_k127_2414088_17 integral membrane protein - - - 0.000001125 61.0
SHD3_k127_2414088_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 480.0
SHD3_k127_2414088_3 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 448.0
SHD3_k127_2414088_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 443.0
SHD3_k127_2414088_5 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 417.0
SHD3_k127_2414088_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 419.0
SHD3_k127_2414088_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 375.0
SHD3_k127_2414088_8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 356.0
SHD3_k127_2414088_9 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 308.0
SHD3_k127_2434888_0 sensor diguanylate cyclase phosphodiesterase - - - 0.00000000000000000000000006377 120.0
SHD3_k127_2434888_1 PFAM response regulator receiver - - - 0.000000000003093 78.0
SHD3_k127_2434888_2 Histidine Phosphotransfer domain - - - 0.000000000009779 76.0
SHD3_k127_2442629_0 nucleotide-excision repair K03701 - - 1.84e-261 833.0
SHD3_k127_2442629_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 1.82e-217 687.0
SHD3_k127_2442629_2 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 527.0
SHD3_k127_2442629_3 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 417.0
SHD3_k127_2442629_4 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 388.0
SHD3_k127_2447384_0 Sel1-like repeats. K07126 - - 0.000000000000000000000005605 104.0
SHD3_k127_2447883_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 509.0
SHD3_k127_2447883_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 327.0
SHD3_k127_2447883_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000002145 215.0
SHD3_k127_2447883_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000002523 84.0
SHD3_k127_2447883_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00008333 51.0
SHD3_k127_2462216_1 Diguanylate cyclase - - - 0.00000000000000000001072 94.0
SHD3_k127_2462216_2 - - - - 0.000000005217 64.0
SHD3_k127_2469992_1 PilZ domain - - - 0.00003278 52.0
SHD3_k127_2471729_0 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 543.0
SHD3_k127_2471729_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 311.0
SHD3_k127_2471729_2 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001487 243.0
SHD3_k127_2471729_3 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000001447 243.0
SHD3_k127_2471729_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000002627 222.0
SHD3_k127_2471729_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000005041 200.0
SHD3_k127_2471729_6 MGS-like domain - - - 0.000000000000000000000000000000000000000000000000001467 191.0
SHD3_k127_2471729_7 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000008793 166.0
SHD3_k127_2471729_8 - - - - 0.000000000000000000000006548 109.0
SHD3_k127_2480314_0 Belongs to the sulfur carrier protein TusA family - - - 0.00000000008097 65.0
SHD3_k127_2480314_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000004224 66.0
SHD3_k127_2480314_2 DsrE family K06039 - - 0.0004874 46.0
SHD3_k127_2481528_0 CsbD-like - - - 0.000000000000000000000000009349 110.0
SHD3_k127_2481528_1 - - - - 0.000000000000002219 76.0
SHD3_k127_248379_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 479.0
SHD3_k127_248379_1 YtkA-like - - - 0.000000001101 65.0
SHD3_k127_250694_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 596.0
SHD3_k127_250694_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 493.0
SHD3_k127_250694_2 PEP-CTERM exosortase 1-associated glycosyltransferase, Daro_2409 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 414.0
SHD3_k127_250694_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 396.0
SHD3_k127_250694_5 PFAM VanZ family protein - - - 0.00000000000000000000000000000000000000000000005013 179.0
SHD3_k127_250694_6 Methyltransferase domain - - - 0.0000000000000000000000000000009971 130.0
SHD3_k127_250694_7 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000001501 58.0
SHD3_k127_2508044_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 506.0
SHD3_k127_2508301_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1089.0
SHD3_k127_2508301_1 Molecular chaperone. Has ATPase activity K04079 - - 1.854e-267 837.0
SHD3_k127_2508301_10 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 471.0
SHD3_k127_2508301_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 454.0
SHD3_k127_2508301_12 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 451.0
SHD3_k127_2508301_13 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 407.0
SHD3_k127_2508301_14 HlyD membrane-fusion protein of T1SS K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 379.0
SHD3_k127_2508301_15 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 311.0
SHD3_k127_2508301_16 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 296.0
SHD3_k127_2508301_17 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008263 279.0
SHD3_k127_2508301_18 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001524 259.0
SHD3_k127_2508301_19 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009167 252.0
SHD3_k127_2508301_2 Domain in cystathionine beta-synthase and other proteins. K07182 - - 2.244e-256 805.0
SHD3_k127_2508301_20 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000005009 222.0
SHD3_k127_2508301_21 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000001186 220.0
SHD3_k127_2508301_22 Maf-like protein K06287 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.0000000000000000000000000000000000000000000000000007662 190.0
SHD3_k127_2508301_23 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000004781 143.0
SHD3_k127_2508301_24 Protein of unknown function, DUF485 - - - 0.000000000000000000000000002585 114.0
SHD3_k127_2508301_25 SMART Cold shock protein K03704 - - 0.000000000000000000000000007154 110.0
SHD3_k127_2508301_26 Protein of unknown function, DUF488 - - - 0.00000000000000000004538 91.0
SHD3_k127_2508301_27 carbon dioxide binding K04653 - - 0.00000000000000004121 86.0
SHD3_k127_2508301_28 PFAM Tetratricopeptide repeat - - - 0.00000165 57.0
SHD3_k127_2508301_3 PD-(D/E)XK nuclease superfamily - - - 4.952e-242 782.0
SHD3_k127_2508301_4 Sugar (and other) transporter K03446 - - 1.597e-234 735.0
SHD3_k127_2508301_5 Belongs to the helicase family. UvrD subfamily - - - 1.822e-227 736.0
SHD3_k127_2508301_6 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 1.272e-225 721.0
SHD3_k127_2508301_7 ABC-type antimicrobial peptide transport system, permease component K02004 - - 1.715e-199 627.0
SHD3_k127_2508301_8 Sodium:solute symporter family K14393 - - 3.536e-197 630.0
SHD3_k127_2508301_9 His Kinase A (phospho-acceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 573.0
SHD3_k127_2514412_0 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 9.646e-202 640.0
SHD3_k127_2514412_1 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 350.0
SHD3_k127_2514412_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 331.0
SHD3_k127_2530272_0 transposition K07497 - - 0.000000000000000000000000000000000000000000000000000000002134 214.0
SHD3_k127_2530272_1 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0003267 46.0
SHD3_k127_2538512_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1328.0
SHD3_k127_2538512_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1161.0
SHD3_k127_2538512_10 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 263.0
SHD3_k127_2538512_11 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000312 254.0
SHD3_k127_2538512_12 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000001163 239.0
SHD3_k127_2538512_13 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000003902 238.0
SHD3_k127_2538512_14 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000006947 224.0
SHD3_k127_2538512_15 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000002017 203.0
SHD3_k127_2538512_16 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000001743 196.0
SHD3_k127_2538512_17 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000001723 149.0
SHD3_k127_2538512_18 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000002491 125.0
SHD3_k127_2538512_19 COG3209 Rhs family protein - - - 0.00000000000000000000000006358 112.0
SHD3_k127_2538512_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.609e-284 883.0
SHD3_k127_2538512_20 Transcriptional regulator, arsR family - - - 0.0000000000000000000000004427 108.0
SHD3_k127_2538512_21 - - - - 0.000000000000000000000008487 108.0
SHD3_k127_2538512_22 SMART Tetratricopeptide - - - 0.000000000000000000000012 108.0
SHD3_k127_2538512_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 8.549e-195 616.0
SHD3_k127_2538512_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.432e-194 613.0
SHD3_k127_2538512_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 571.0
SHD3_k127_2538512_6 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 482.0
SHD3_k127_2538512_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 439.0
SHD3_k127_2538512_8 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 386.0
SHD3_k127_2538512_9 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003209 271.0
SHD3_k127_2617335_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.118e-225 702.0
SHD3_k127_2617335_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000004605 242.0
SHD3_k127_2617335_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000005644 205.0
SHD3_k127_2617335_3 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000025 165.0
SHD3_k127_2651068_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 406.0
SHD3_k127_2651068_1 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001547 221.0
SHD3_k127_2651068_2 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000002354 183.0
SHD3_k127_2651068_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000003982 179.0
SHD3_k127_2651068_4 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.0000000000000000000000006943 104.0
SHD3_k127_2658731_0 ABC transporter K06020 - 3.6.3.25 2.113e-311 959.0
SHD3_k127_2658731_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 550.0
SHD3_k127_2658731_10 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000001039 198.0
SHD3_k127_2658731_11 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.0000000000000000000000000000000000000000000000004971 185.0
SHD3_k127_2658731_12 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000000003954 118.0
SHD3_k127_2658731_13 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.0000000000000000000000003214 114.0
SHD3_k127_2658731_14 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.000000000000000000004142 96.0
SHD3_k127_2658731_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 527.0
SHD3_k127_2658731_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 524.0
SHD3_k127_2658731_4 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 442.0
SHD3_k127_2658731_5 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 335.0
SHD3_k127_2658731_6 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 333.0
SHD3_k127_2658731_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 325.0
SHD3_k127_2658731_8 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 286.0
SHD3_k127_2658731_9 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000124 221.0
SHD3_k127_2662002_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0 1086.0
SHD3_k127_2662002_1 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 423.0
SHD3_k127_2662002_10 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0001496 44.0
SHD3_k127_2662002_11 E3 Ubiquitin ligase - - - 0.0004875 51.0
SHD3_k127_2662002_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 414.0
SHD3_k127_2662002_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006644 260.0
SHD3_k127_2662002_4 2Fe-2S -binding domain K13483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007168 259.0
SHD3_k127_2662002_5 LemA family K03744 - - 0.0000000000000000000000000000000000000000001531 165.0
SHD3_k127_2662002_6 LemA family K03744 - - 0.000000000000000000000000000000000006156 143.0
SHD3_k127_2662002_7 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000107 108.0
SHD3_k127_2662002_8 Membrane - - - 0.00000000005491 68.0
SHD3_k127_2662002_9 HEAT repeat-containing protein - - - 0.0001331 55.0
SHD3_k127_2728339_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 516.0
SHD3_k127_2773704_0 cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 383.0
SHD3_k127_2773704_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 315.0
SHD3_k127_2773704_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000001513 247.0
SHD3_k127_2773704_3 - - - - 0.0000000000000000000000000000000000000000000721 183.0
SHD3_k127_2773704_4 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000003712 118.0
SHD3_k127_2773704_5 - - - - 0.000000000000000000000001387 111.0
SHD3_k127_2773704_6 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000003731 103.0
SHD3_k127_2794708_0 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 1.325e-196 633.0
SHD3_k127_2794708_1 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 340.0
SHD3_k127_2794708_2 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003939 258.0
SHD3_k127_2794708_3 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000001161 240.0
SHD3_k127_2794708_4 - - - - 0.0000001568 54.0
SHD3_k127_27957_0 Sigma-54 interaction domain - - - 9.098e-212 666.0
SHD3_k127_27957_1 Clostripain family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 442.0
SHD3_k127_27957_10 helix_turn_helix gluconate operon transcriptional repressor K03710 - - 0.000000000000000000000000000000008466 137.0
SHD3_k127_27957_11 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000002544 132.0
SHD3_k127_27957_12 Histidine kinase K19661 - 2.7.13.3 0.000000000000000000001914 96.0
SHD3_k127_27957_13 methyl-accepting chemotaxis protein K03406 - - 0.0000000006479 63.0
SHD3_k127_27957_14 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000001955 62.0
SHD3_k127_27957_15 Universal stress protein A-like protein - GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016208,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00003191 53.0
SHD3_k127_27957_2 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 412.0
SHD3_k127_27957_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 403.0
SHD3_k127_27957_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 378.0
SHD3_k127_27957_5 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 358.0
SHD3_k127_27957_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 307.0
SHD3_k127_27957_7 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005178 297.0
SHD3_k127_27957_8 Histidine kinase - - - 0.0000000000000000000000000000000000000002243 169.0
SHD3_k127_280764_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 3.254e-236 739.0
SHD3_k127_280764_1 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 6.716e-195 618.0
SHD3_k127_280764_10 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000000000000000000001791 188.0
SHD3_k127_280764_11 phosphatase activity K05967 - - 0.000000000000000000000000000000000000000006324 160.0
SHD3_k127_280764_12 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000004262 149.0
SHD3_k127_280764_13 Type II secretion system protein B K02451 - - 0.000000000000001118 85.0
SHD3_k127_280764_14 NADH dehydrogenase - - - 0.000000000000009866 75.0
SHD3_k127_280764_16 Protein of unknown function (DUF2934) - - - 0.00005518 49.0
SHD3_k127_280764_2 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 476.0
SHD3_k127_280764_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 412.0
SHD3_k127_280764_4 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 389.0
SHD3_k127_280764_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 347.0
SHD3_k127_280764_6 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000003505 242.0
SHD3_k127_280764_7 PFAM NADH Ubiquinone - - - 0.00000000000000000000000000000000000000000000000000000000000000008964 227.0
SHD3_k127_280764_8 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000006478 220.0
SHD3_k127_280764_9 - - - - 0.000000000000000000000000000000000000000000000000000000004718 204.0
SHD3_k127_2863026_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 558.0
SHD3_k127_2863026_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006275 244.0
SHD3_k127_2863026_2 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000003921 235.0
SHD3_k127_2863026_3 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000002838 197.0
SHD3_k127_2863026_4 trisaccharide binding - - - 0.000000000000000000000000000000000000000000002377 169.0
SHD3_k127_2863026_5 - - - - 0.0000000000000000000000000000000004247 134.0
SHD3_k127_2869325_0 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 531.0
SHD3_k127_2869325_1 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003587 242.0
SHD3_k127_2869325_2 - - - - 0.000000000000000000000000000000000000000706 158.0
SHD3_k127_2870844_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1401.0
SHD3_k127_2870844_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 488.0
SHD3_k127_2870844_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 432.0
SHD3_k127_2870844_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 377.0
SHD3_k127_2870844_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000008686 141.0
SHD3_k127_2870844_5 cell redox homeostasis - - - 0.00000000000000000000003644 100.0
SHD3_k127_2870844_6 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000002253 74.0
SHD3_k127_2870844_7 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000005985 74.0
SHD3_k127_2872263_0 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000101 278.0
SHD3_k127_2872263_1 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.0000000000000000000000000000000001694 134.0
SHD3_k127_2872263_2 - - - - 0.0003215 45.0
SHD3_k127_2872639_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 546.0
SHD3_k127_2872639_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 481.0
SHD3_k127_2872639_2 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 386.0
SHD3_k127_2872639_3 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
SHD3_k127_2872639_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 321.0
SHD3_k127_2872639_5 GYD domain - - - 0.000000000000000000000000000000000009372 138.0
SHD3_k127_2872639_6 sulfur carrier activity K04085 - - 0.00000000000000000000000117 104.0
SHD3_k127_2872639_7 - - - - 0.00000089 51.0
SHD3_k127_2872639_8 PEP-CTERM motif - - - 0.0000192 55.0
SHD3_k127_2873415_0 COG NOG14600 non supervised orthologous group - - - 0.00000000000000001052 84.0
SHD3_k127_2873415_5 - - - - 0.0002609 48.0
SHD3_k127_2880464_0 transglycosylase K08309 - - 0.00000009581 62.0
SHD3_k127_2882844_0 Domain of unknown function (DUF4139) - - - 2.602e-197 628.0
SHD3_k127_2882844_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 563.0
SHD3_k127_2882844_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 485.0
SHD3_k127_2882844_3 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000001002 198.0
SHD3_k127_2882844_4 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000000000004438 193.0
SHD3_k127_2882844_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000006985 194.0
SHD3_k127_2882844_6 PFAM Smr protein MutS2 - - - 0.000000000000000000000000001257 121.0
SHD3_k127_2882844_7 response to copper ion - - - 0.000000000000000000005216 104.0
SHD3_k127_2883913_0 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000005678 117.0
SHD3_k127_2889122_0 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000004984 181.0
SHD3_k127_2889122_2 Protein of unknown function (DUF1523) - - - 0.000009161 49.0
SHD3_k127_2898029_0 GTP-binding protein TypA K06207 - - 6.744e-265 827.0
SHD3_k127_2898029_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 547.0
SHD3_k127_2898029_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000001739 257.0
SHD3_k127_2898029_11 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000003385 240.0
SHD3_k127_2898029_12 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000003279 218.0
SHD3_k127_2898029_13 Signal transduction histidine kinase, nitrogen specific K07708 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000246 192.0
SHD3_k127_2898029_14 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000436 167.0
SHD3_k127_2898029_15 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000457 164.0
SHD3_k127_2898029_16 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000004017 153.0
SHD3_k127_2898029_17 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000005429 93.0
SHD3_k127_2898029_18 - - - - 0.000002525 49.0
SHD3_k127_2898029_19 - - - - 0.0001385 46.0
SHD3_k127_2898029_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 504.0
SHD3_k127_2898029_21 - - - - 0.000359 49.0
SHD3_k127_2898029_3 response regulator K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 413.0
SHD3_k127_2898029_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 412.0
SHD3_k127_2898029_5 Transcriptional regulator K11921,K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 378.0
SHD3_k127_2898029_6 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 357.0
SHD3_k127_2898029_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 332.0
SHD3_k127_2898029_8 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 309.0
SHD3_k127_2898678_0 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 351.0
SHD3_k127_2898678_1 ABC-2 type transporter K09690 - - 0.000001301 50.0
SHD3_k127_2899925_0 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000000001914 176.0
SHD3_k127_2902048_0 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000009183 224.0
SHD3_k127_2902048_1 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.000000000005709 66.0
SHD3_k127_2913442_0 PFAM FAD linked oxidase domain protein K00004,K00102,K00104 GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.1.1.303,1.1.1.4,1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001546 251.0
SHD3_k127_2913442_1 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000000002293 91.0
SHD3_k127_2913442_2 In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000000003836 68.0
SHD3_k127_2914703_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 7.749e-263 823.0
SHD3_k127_2914703_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001103 281.0
SHD3_k127_2914703_2 4Fe-4S dicluster domain K00196 - - 0.00000000000000000000000000000000000000000000000007124 182.0
SHD3_k127_2914703_3 - - - - 0.00000000000000000000000000000002268 132.0
SHD3_k127_2914860_0 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001617 278.0
SHD3_k127_2916103_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 429.0
SHD3_k127_2916103_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 316.0
SHD3_k127_2920640_0 TIGRFAM alpha-glucan - - - 0.0 1413.0
SHD3_k127_2920640_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 4.889e-231 726.0
SHD3_k127_2920640_2 phosphonoacetaldehyde hydrolase activity K00817,K07025,K20866 - 2.6.1.9,3.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 297.0
SHD3_k127_2920640_3 type IV pilus assembly PilZ - - - 0.0000000000004377 75.0
SHD3_k127_2920640_4 PFAM EAL domain, GGDEF domain - - - 0.000000002436 59.0
SHD3_k127_29304_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000785 179.0
SHD3_k127_29304_2 DGC domain - - - 0.00000000000000362 76.0
SHD3_k127_29304_3 Short C-terminal domain K08982 - - 0.0000001766 56.0
SHD3_k127_2934459_0 DJ-1/PfpI family K03152 - 3.5.1.124 0.0000000000000000001085 89.0
SHD3_k127_2934459_1 PFAM amino acid-binding ACT domain protein - - - 0.00002906 52.0
SHD3_k127_2934633_0 PFAM membrane bound O-acyl transferase MBOAT K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 530.0
SHD3_k127_2934633_1 Glycosyl transferase, family 2 K16555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 497.0
SHD3_k127_2934633_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 462.0
SHD3_k127_2934633_3 glycosyl transferase group 1 K20444 - - 0.00000000000000000000000000000000000000000000000006316 186.0
SHD3_k127_2934633_4 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.00000000000000000000000000000000000000000000000009042 193.0
SHD3_k127_2936417_0 reverse transcriptase K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 426.0
SHD3_k127_2936417_1 protein kinase activity K08884 - 2.7.11.1 0.0000000000000000005903 91.0
SHD3_k127_2937195_0 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001053 261.0
SHD3_k127_2937195_1 - - - - 0.000000000001033 71.0
SHD3_k127_2937195_2 PFAM nuclease (SNase domain protein) - - - 0.00000003413 61.0
SHD3_k127_2937944_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 460.0
SHD3_k127_2937944_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 408.0
SHD3_k127_2937944_2 - - - - 0.00000000000000000000000000000000000000000000000000008446 191.0
SHD3_k127_2937944_3 HD domain K07814 - - 0.000000000000000000207 98.0
SHD3_k127_2953438_0 NADH-quinone oxidoreductase K00341 - 1.6.5.3 3.793e-244 769.0
SHD3_k127_2953438_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 567.0
SHD3_k127_2953438_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000003601 151.0
SHD3_k127_2953438_11 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000001336 147.0
SHD3_k127_2953438_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000001099 125.0
SHD3_k127_2953438_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 533.0
SHD3_k127_2953438_3 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 531.0
SHD3_k127_2953438_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 481.0
SHD3_k127_2953438_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 420.0
SHD3_k127_2953438_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000008755 252.0
SHD3_k127_2953438_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000561 206.0
SHD3_k127_2953438_8 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000004617 160.0
SHD3_k127_2953438_9 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000001554 157.0
SHD3_k127_2954412_0 Membrane - - - 0.0000000000000000005672 93.0
SHD3_k127_2954412_1 Peptidase family M23 - - - 0.0000003484 56.0
SHD3_k127_2960523_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 344.0
SHD3_k127_2960523_1 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 293.0
SHD3_k127_2960523_2 - - - - 0.000000000000000000000000003726 113.0
SHD3_k127_2960523_3 - - - - 0.000000000000000000002283 95.0
SHD3_k127_2960523_4 - - - - 0.0000000000000003467 78.0
SHD3_k127_2960523_5 - - - - 0.0000000000000007555 79.0
SHD3_k127_2960523_6 BON domain K04065 - - 0.000000000000001056 81.0
SHD3_k127_2960523_7 - - - - 0.0000000007545 60.0
SHD3_k127_2963163_0 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 440.0
SHD3_k127_2963163_2 - - - - 0.0000000000000000000001866 97.0
SHD3_k127_2963977_0 Aconitase C-terminal domain K01681 - 4.2.1.3 5.276e-297 922.0
SHD3_k127_2968766_0 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 479.0
SHD3_k127_2968766_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 444.0
SHD3_k127_2968766_10 - - - - 0.0000000000000000000000000000000000000000000000007364 180.0
SHD3_k127_2968766_11 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000004081 160.0
SHD3_k127_2968766_12 Membrane - - - 0.000000000000000000000001667 112.0
SHD3_k127_2968766_13 - - - - 0.00000000000000002447 89.0
SHD3_k127_2968766_14 Membrane - - - 0.000000000000001122 87.0
SHD3_k127_2968766_15 - - - - 0.00000000007609 63.0
SHD3_k127_2968766_16 ABC transporter K06158 - - 0.00000002141 57.0
SHD3_k127_2968766_17 Transposase IS200 like - - - 0.000158 45.0
SHD3_k127_2968766_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 447.0
SHD3_k127_2968766_3 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 431.0
SHD3_k127_2968766_4 PFAM MscS Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 382.0
SHD3_k127_2968766_5 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 340.0
SHD3_k127_2968766_6 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 332.0
SHD3_k127_2968766_7 aminopeptidase N - - - 0.00000000000000000000000000000000000000000000000000000008069 208.0
SHD3_k127_2973089_0 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 432.0
SHD3_k127_2973089_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000004575 186.0
SHD3_k127_2974011_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000002547 230.0
SHD3_k127_2975222_0 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002396 274.0
SHD3_k127_2975222_1 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000001367 118.0
SHD3_k127_2975815_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 6.4e-323 998.0
SHD3_k127_2975815_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.481e-292 914.0
SHD3_k127_2975815_10 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 548.0
SHD3_k127_2975815_11 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 503.0
SHD3_k127_2975815_12 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 498.0
SHD3_k127_2975815_13 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 490.0
SHD3_k127_2975815_14 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 454.0
SHD3_k127_2975815_15 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 439.0
SHD3_k127_2975815_16 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 391.0
SHD3_k127_2975815_17 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 344.0
SHD3_k127_2975815_18 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 338.0
SHD3_k127_2975815_19 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 328.0
SHD3_k127_2975815_2 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.789e-268 845.0
SHD3_k127_2975815_20 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 325.0
SHD3_k127_2975815_21 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 312.0
SHD3_k127_2975815_22 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 331.0
SHD3_k127_2975815_23 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 311.0
SHD3_k127_2975815_24 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009387 306.0
SHD3_k127_2975815_25 helix_turn_helix, Lux Regulon K02282,K07689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 296.0
SHD3_k127_2975815_26 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007561 268.0
SHD3_k127_2975815_27 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 265.0
SHD3_k127_2975815_28 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000001762 263.0
SHD3_k127_2975815_29 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003525 270.0
SHD3_k127_2975815_3 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 4.364e-232 725.0
SHD3_k127_2975815_30 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000181 254.0
SHD3_k127_2975815_31 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004244 271.0
SHD3_k127_2975815_32 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000146 253.0
SHD3_k127_2975815_33 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000004537 236.0
SHD3_k127_2975815_34 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000003383 227.0
SHD3_k127_2975815_35 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000002305 217.0
SHD3_k127_2975815_36 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000004584 214.0
SHD3_k127_2975815_37 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000003152 219.0
SHD3_k127_2975815_38 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000006032 212.0
SHD3_k127_2975815_39 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000000000000000000000000000000000000001635 202.0
SHD3_k127_2975815_4 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 1.633e-227 720.0
SHD3_k127_2975815_40 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000004367 191.0
SHD3_k127_2975815_41 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.00000000000000000000000000000000000000000000000000007192 193.0
SHD3_k127_2975815_42 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000005036 188.0
SHD3_k127_2975815_43 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000002709 177.0
SHD3_k127_2975815_44 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.0000000000000000000000000000000000000000001105 170.0
SHD3_k127_2975815_45 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000001071 178.0
SHD3_k127_2975815_46 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000003777 167.0
SHD3_k127_2975815_47 PFAM CBS domain - - - 0.000000000000000000000000000000000004654 141.0
SHD3_k127_2975815_49 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000001072 134.0
SHD3_k127_2975815_5 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 5.741e-225 715.0
SHD3_k127_2975815_50 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000005366 115.0
SHD3_k127_2975815_51 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000002545 112.0
SHD3_k127_2975815_52 Hydrolase, P-loop family K06925 - - 0.0000000000000000000000002948 110.0
SHD3_k127_2975815_53 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000001009 98.0
SHD3_k127_2975815_54 Protein of unknown function (DUF2905) - - - 0.00000000000000000006758 93.0
SHD3_k127_2975815_55 PFAM Methylamine - - - 0.0000000000000001263 86.0
SHD3_k127_2975815_56 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000002008 61.0
SHD3_k127_2975815_57 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000005111 62.0
SHD3_k127_2975815_59 peptidyl-tyrosine sulfation - - - 0.0004021 47.0
SHD3_k127_2975815_6 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 605.0
SHD3_k127_2975815_7 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 604.0
SHD3_k127_2975815_8 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 587.0
SHD3_k127_2975815_9 family UPF0324 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 581.0
SHD3_k127_2980807_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.592e-295 914.0
SHD3_k127_2980807_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 387.0
SHD3_k127_2980807_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 299.0
SHD3_k127_2980807_3 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000009538 259.0
SHD3_k127_2980807_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006401 261.0
SHD3_k127_2980807_5 NosL - - - 0.000000000000000000000000000000000000003428 153.0
SHD3_k127_2980807_6 - - - - 0.00000000000001092 77.0
SHD3_k127_2980807_7 DsrE/DsrF/DrsH-like family - - - 0.00000000000006029 77.0
SHD3_k127_2980807_8 membrane transporter protein K07090 - - 0.000000261 53.0
SHD3_k127_2983617_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 357.0
SHD3_k127_2985188_0 Dehydratase family K01687 - 4.2.1.9 3.607e-264 824.0
SHD3_k127_2985188_1 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.017e-244 771.0
SHD3_k127_2985188_10 Formyl transferase - - - 0.000000000000000000000000000000002324 140.0
SHD3_k127_2985188_11 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000001177 128.0
SHD3_k127_2985188_12 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000008201 88.0
SHD3_k127_2985188_13 Tetratricopeptide repeat - - - 0.0000000000002387 79.0
SHD3_k127_2985188_14 Polysaccharide deacetylase - - - 0.0000000000004567 80.0
SHD3_k127_2985188_2 domain, Protein K01176,K03332 - 3.2.1.1,3.2.1.80 5.115e-221 707.0
SHD3_k127_2985188_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 456.0
SHD3_k127_2985188_4 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 416.0
SHD3_k127_2985188_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 374.0
SHD3_k127_2985188_6 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 372.0
SHD3_k127_2985188_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 322.0
SHD3_k127_2985188_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000004081 257.0
SHD3_k127_2985188_9 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000003516 198.0
SHD3_k127_2992434_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 525.0
SHD3_k127_2992434_1 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 385.0
SHD3_k127_2992434_2 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0000000000000000000000000000000000000000000000000000000004836 207.0
SHD3_k127_2992434_3 - - - - 0.00000000000000000000000000000000000003245 146.0
SHD3_k127_2992434_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000001775 128.0
SHD3_k127_2993292_0 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00006231 55.0
SHD3_k127_2994187_0 Alpha-glucan water dikinase K08244 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009608,GO:0009610,GO:0009620,GO:0009628,GO:0009631,GO:0009941,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0031967,GO:0031975,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050521,GO:0050896,GO:0051704,GO:0051707,GO:0071704,GO:1901575 2.7.9.4 8.547e-232 753.0
SHD3_k127_2994187_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 4.611e-206 649.0
SHD3_k127_2994187_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000001264 206.0
SHD3_k127_2994187_11 superoxide reductase activity K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000000000000001883 208.0
SHD3_k127_2994187_12 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000008149 192.0
SHD3_k127_2994187_13 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000000006097 181.0
SHD3_k127_2994187_14 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.00000000000000000000000000000000000000000000002201 174.0
SHD3_k127_2994187_15 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000005739 123.0
SHD3_k127_2994187_16 AhpC/TSA family K03386 - 1.11.1.15 0.000000000000002557 76.0
SHD3_k127_2994187_17 - K07092 - - 0.0003288 48.0
SHD3_k127_2994187_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 583.0
SHD3_k127_2994187_3 Phosphoglucan, water dikinase K15535 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019200,GO:0019538,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044275,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046777,GO:0046835,GO:0051752,GO:0071704,GO:1901564,GO:1901575 2.7.9.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 588.0
SHD3_k127_2994187_4 Alpha amylase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 543.0
SHD3_k127_2994187_5 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 468.0
SHD3_k127_2994187_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 346.0
SHD3_k127_2994187_7 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 327.0
SHD3_k127_2994187_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
SHD3_k127_2994187_9 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001311 241.0
SHD3_k127_3002339_1 - - - - 0.0001721 50.0
SHD3_k127_3005985_0 transporter antisigma-factor antagonist STAS K03321 - - 6.435e-221 699.0
SHD3_k127_3013973_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 525.0
SHD3_k127_3013973_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00001661 47.0
SHD3_k127_3016083_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 397.0
SHD3_k127_3016083_1 sugar transferase K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 391.0
SHD3_k127_3016083_2 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001069 280.0
SHD3_k127_3016083_3 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000006745 233.0
SHD3_k127_3016083_5 - - - - 0.000000000003836 68.0
SHD3_k127_3016083_6 Glycosyltransferase like family 2 - - - 0.00000003653 58.0
SHD3_k127_3017655_0 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000005262 141.0
SHD3_k127_3017655_1 denitrification pathway - - - 0.0000000000002975 75.0
SHD3_k127_3018682_0 Fibronectin type III - - - 0.00000000000000000005805 100.0
SHD3_k127_3026212_0 Flavodoxin-like fold K19784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007473 276.0
SHD3_k127_3026212_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000002942 135.0
SHD3_k127_3026320_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001439 282.0
SHD3_k127_3026320_1 DDE_Tnp_1-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007919 269.0
SHD3_k127_3029319_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 432.0
SHD3_k127_3029319_1 RDD family - - - 0.00000000000000000000000002343 113.0
SHD3_k127_3035298_0 Acyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 333.0
SHD3_k127_3035298_1 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000000000006216 209.0
SHD3_k127_3035571_0 SMART Rhodanese domain protein - - - 0.0000000000000000000000000000000000000006029 160.0
SHD3_k127_3035571_1 PFAM Phosphate-selective porin O and P - - - 0.00000000000261 68.0
SHD3_k127_3035571_2 PFAM Phosphate-selective porin O and P - - - 0.0000000003163 63.0
SHD3_k127_3035571_3 thiosulfate sulfurtransferase activity - - - 0.0004584 47.0
SHD3_k127_3045863_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000006595 136.0
SHD3_k127_3045969_0 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 493.0
SHD3_k127_3049850_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1163.0
SHD3_k127_3049850_1 K transport systems K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 381.0
SHD3_k127_3049850_2 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 321.0
SHD3_k127_3049850_3 LemA family K03744 - - 0.0000002624 57.0
SHD3_k127_3056361_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 398.0
SHD3_k127_3056361_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00002354 48.0
SHD3_k127_3061764_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 582.0
SHD3_k127_3061764_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 554.0
SHD3_k127_3061764_2 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 506.0
SHD3_k127_3061764_3 phosphosulfolactate synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009933 422.0
SHD3_k127_3062396_0 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 7.817e-253 797.0
SHD3_k127_3062396_1 GTP-binding GTPase Middle Region K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 615.0
SHD3_k127_3062396_2 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 593.0
SHD3_k127_3062396_3 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 466.0
SHD3_k127_3062396_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 459.0
SHD3_k127_3062396_5 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 466.0
SHD3_k127_3062396_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 436.0
SHD3_k127_3062396_7 belongs to the CobB CobQ family K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 318.0
SHD3_k127_3062396_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 289.0
SHD3_k127_3062396_9 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000001176 226.0
SHD3_k127_3074865_0 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000000000000000000001953 181.0
SHD3_k127_3077910_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 490.0
SHD3_k127_3077910_1 MgtC SapB transporter K07507 - - 0.000000000000007712 75.0
SHD3_k127_3078189_0 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 335.0
SHD3_k127_3079905_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1556.0
SHD3_k127_3079905_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 306.0
SHD3_k127_3079905_2 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000007488 268.0
SHD3_k127_3079905_3 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000001009 219.0
SHD3_k127_3079905_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000003555 193.0
SHD3_k127_3079905_5 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000001197 102.0
SHD3_k127_3079905_6 PSP1 C-terminal domain protein - - - 0.000000002702 59.0
SHD3_k127_3079905_7 Type IV minor pilin ComP, DNA uptake sequence receptor K02650 - - 0.000000006079 64.0
SHD3_k127_3079905_8 Prokaryotic N-terminal methylation motif K02650 - - 0.000001304 58.0
SHD3_k127_3094859_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 535.0
SHD3_k127_3094859_1 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 398.0
SHD3_k127_3094859_2 Cys/Met metabolism PLP-dependent enzyme K01760,K01761 - 4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 372.0
SHD3_k127_3094859_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000004688 187.0
SHD3_k127_3094859_4 Cold shock K03704 - - 0.000000000000000000000003942 102.0
SHD3_k127_3094859_5 PFAM 4Fe-4S K00176 - 1.2.7.3 0.00000000000000000003779 92.0
SHD3_k127_3097413_0 TIGRFAM cysteine K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 373.0
SHD3_k127_3097413_1 Cold shock K03704 - - 0.000000000000000000000000002764 111.0
SHD3_k127_3097413_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000409 65.0
SHD3_k127_3107190_0 - - - - 0.0000000000000000000000001207 109.0
SHD3_k127_3107190_1 - - - - 0.00000000000000000000184 96.0
SHD3_k127_3107190_2 ORF located using Blastx - - - 0.00000000004918 65.0
SHD3_k127_3107190_3 ORF located using Blastx - - - 0.0000000003413 61.0
SHD3_k127_3107361_0 PFAM Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000153 256.0
SHD3_k127_3107361_1 IMG reference gene - - - 0.00000000000000005256 84.0
SHD3_k127_3108545_0 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000479 185.0
SHD3_k127_3116066_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.067e-229 714.0
SHD3_k127_3116066_1 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 304.0
SHD3_k127_3116066_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000004161 203.0
SHD3_k127_3116066_3 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000000000006123 193.0
SHD3_k127_3116066_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000001047 138.0
SHD3_k127_3116066_5 Protein of unknown function (DUF1059) - - - 0.000000006154 58.0
SHD3_k127_3127453_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 9.956e-280 891.0
SHD3_k127_3127453_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.643e-274 858.0
SHD3_k127_3127453_10 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 388.0
SHD3_k127_3127453_11 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 318.0
SHD3_k127_3127453_12 COG1194 A G-specific DNA glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 294.0
SHD3_k127_3127453_13 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000007308 233.0
SHD3_k127_3127453_14 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000008294 210.0
SHD3_k127_3127453_15 - - - - 0.000000000000000000000000000000000000000000000000000000459 198.0
SHD3_k127_3127453_16 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000000003893 163.0
SHD3_k127_3127453_17 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000001112 161.0
SHD3_k127_3127453_18 YceI-like domain - - - 0.0000000000000000000000000000000000000003521 156.0
SHD3_k127_3127453_19 heat shock protein binding - - - 0.0000000000000000000000000000000000319 147.0
SHD3_k127_3127453_2 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 2.754e-241 760.0
SHD3_k127_3127453_20 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000001206 137.0
SHD3_k127_3127453_21 Domain of unknown function DUF302 - - - 0.0000000000000000000000000001198 127.0
SHD3_k127_3127453_22 - - - - 0.0000000000000000000000000005855 120.0
SHD3_k127_3127453_23 protein complex oligomerization - - - 0.000000000000000000000008235 107.0
SHD3_k127_3127453_24 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000002622 102.0
SHD3_k127_3127453_26 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.000000000000004737 81.0
SHD3_k127_3127453_27 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000001363 59.0
SHD3_k127_3127453_28 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000003119 59.0
SHD3_k127_3127453_3 Aminotransferase class-III K01845 - 5.4.3.8 9.308e-203 638.0
SHD3_k127_3127453_4 Polysulphide reductase, NrfD - - - 1.052e-195 617.0
SHD3_k127_3127453_6 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 503.0
SHD3_k127_3127453_7 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009351 496.0
SHD3_k127_3127453_8 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 436.0
SHD3_k127_3127453_9 HMGL-like K01666 - 4.1.3.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 395.0
SHD3_k127_3144334_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 503.0
SHD3_k127_3144334_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 409.0
SHD3_k127_3144334_2 ABC transporter K01996 - - 0.00000000000000000000000000000002191 126.0
SHD3_k127_3148948_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 324.0
SHD3_k127_3148948_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 285.0
SHD3_k127_3148948_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000003952 166.0
SHD3_k127_3148948_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000003053 61.0
SHD3_k127_3154353_0 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000005857 70.0
SHD3_k127_3154461_0 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 485.0
SHD3_k127_3154461_1 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 342.0
SHD3_k127_316226_0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 486.0
SHD3_k127_316226_1 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000000000000000000000000000000005158 141.0
SHD3_k127_316226_2 - - - - 0.00000000000002471 77.0
SHD3_k127_31674_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 439.0
SHD3_k127_31674_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000003476 232.0
SHD3_k127_31674_2 Thiamine-binding protein - - - 0.000000000000000000000000001893 114.0
SHD3_k127_316805_0 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 530.0
SHD3_k127_316805_1 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000006914 220.0
SHD3_k127_3178598_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 344.0
SHD3_k127_3179279_0 Polysaccharide pyruvyl transferase - - - 0.0004768 49.0
SHD3_k127_3182200_0 COG0058 Glucan phosphorylase - - - 2.222e-259 809.0
SHD3_k127_3182200_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 432.0
SHD3_k127_3182200_2 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009062 393.0
SHD3_k127_3182200_3 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000003698 229.0
SHD3_k127_3182200_4 exodeoxyribonuclease I activity - - - 0.00000000000005541 75.0
SHD3_k127_3190184_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000001232 194.0
SHD3_k127_3190184_1 - - - - 0.000000000000000000000000000000000000000000000000000004092 199.0
SHD3_k127_3207651_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 443.0
SHD3_k127_3207651_1 LysE type translocator - - - 0.0000000000000000000000000000000007559 134.0
SHD3_k127_3207651_2 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000003341 128.0
SHD3_k127_3213036_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 358.0
SHD3_k127_3216043_0 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001643 267.0
SHD3_k127_3216373_0 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 481.0
SHD3_k127_3216373_1 - - - - 0.0000000000000000000000000000001798 126.0
SHD3_k127_3216373_2 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000001643 120.0
SHD3_k127_3216373_3 - - - - 0.000000000001458 71.0
SHD3_k127_3227209_0 protein-disulfide reductase activity - - - 0.000000000000000000000000002159 116.0
SHD3_k127_3227209_1 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 - - 0.000000000000000444 82.0
SHD3_k127_3227209_2 - - - - 0.000000005053 57.0
SHD3_k127_3236312_0 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 345.0
SHD3_k127_3236312_1 DsrE/DsrF/DrsH-like family - - - 0.00000006915 55.0
SHD3_k127_3271146_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 348.0
SHD3_k127_3271146_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 331.0
SHD3_k127_3271146_2 glycosyl transferase group 1 - - - 0.000000000000000000000000000000007533 138.0
SHD3_k127_327410_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 456.0
SHD3_k127_3304777_0 the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - 0.000000000000000000000000000000000000000000000000000000000000002204 220.0
SHD3_k127_33052_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 557.0
SHD3_k127_33052_1 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000000000000007554 190.0
SHD3_k127_33052_10 PFAM Phosphate-starvation-inducible E - - - 0.0000302 55.0
SHD3_k127_33052_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000002644 177.0
SHD3_k127_33052_3 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000008776 132.0
SHD3_k127_33052_4 regulatory protein ArsR K03892 - - 0.0000000000000000000000009251 109.0
SHD3_k127_33052_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000005286 85.0
SHD3_k127_33052_6 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000001995 81.0
SHD3_k127_33052_7 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000002176 73.0
SHD3_k127_33052_8 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.0000000000002309 71.0
SHD3_k127_3320059_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1301.0
SHD3_k127_3320059_1 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0 1214.0
SHD3_k127_3320059_10 SEFIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 550.0
SHD3_k127_3320059_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 498.0
SHD3_k127_3320059_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 490.0
SHD3_k127_3320059_13 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 495.0
SHD3_k127_3320059_14 UDP binding domain K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 466.0
SHD3_k127_3320059_15 AAA ATPase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008112 450.0
SHD3_k127_3320059_16 Sulphur transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 434.0
SHD3_k127_3320059_17 GDP-mannose 4,6 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 425.0
SHD3_k127_3320059_18 PFAM Radical SAM K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 413.0
SHD3_k127_3320059_19 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 398.0
SHD3_k127_3320059_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K13378 - 1.6.5.3 6.886e-307 947.0
SHD3_k127_3320059_20 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 403.0
SHD3_k127_3320059_21 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 394.0
SHD3_k127_3320059_22 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 385.0
SHD3_k127_3320059_23 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 381.0
SHD3_k127_3320059_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 342.0
SHD3_k127_3320059_25 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 342.0
SHD3_k127_3320059_27 PFAM Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 349.0
SHD3_k127_3320059_28 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 340.0
SHD3_k127_3320059_29 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 328.0
SHD3_k127_3320059_3 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 2.324e-276 868.0
SHD3_k127_3320059_30 SagB-type dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 322.0
SHD3_k127_3320059_31 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 334.0
SHD3_k127_3320059_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 312.0
SHD3_k127_3320059_33 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 318.0
SHD3_k127_3320059_34 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 313.0
SHD3_k127_3320059_35 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 295.0
SHD3_k127_3320059_36 rRNA (uridine-N3-)-methyltransferase activity K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 293.0
SHD3_k127_3320059_37 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 281.0
SHD3_k127_3320059_38 COGs COG0463 Glycosyltransferase involved in cell wall biogenesis K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001614 280.0
SHD3_k127_3320059_39 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002126 234.0
SHD3_k127_3320059_4 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.657e-236 752.0
SHD3_k127_3320059_40 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000001761 214.0
SHD3_k127_3320059_41 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001057 189.0
SHD3_k127_3320059_42 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000003467 176.0
SHD3_k127_3320059_43 PFAM PHP domain - - - 0.000000000000000000000000000000000000000000001693 171.0
SHD3_k127_3320059_44 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000000000229 164.0
SHD3_k127_3320059_45 Universal stress protein family - - - 0.0000000000000000000000000000000000000000001356 164.0
SHD3_k127_3320059_46 Universal stress protein family - - - 0.00000000000000000000000000000000000000001695 157.0
SHD3_k127_3320059_47 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000002371 155.0
SHD3_k127_3320059_48 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000001131 138.0
SHD3_k127_3320059_49 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000005653 137.0
SHD3_k127_3320059_5 SMART Elongator protein 3 MiaB NifB - - - 3.989e-216 680.0
SHD3_k127_3320059_50 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000001259 140.0
SHD3_k127_3320059_51 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000004236 124.0
SHD3_k127_3320059_52 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000003712 117.0
SHD3_k127_3320059_53 - - - - 0.00000000000000000000000001561 112.0
SHD3_k127_3320059_54 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000006086 103.0
SHD3_k127_3320059_55 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000009227 93.0
SHD3_k127_3320059_56 FecR protein - - - 0.00000000000000000519 93.0
SHD3_k127_3320059_57 - - - - 0.000000000001284 71.0
SHD3_k127_3320059_58 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.000000000001515 80.0
SHD3_k127_3320059_59 Universal stress protein family - - - 0.000000000002311 73.0
SHD3_k127_3320059_6 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 9.056e-209 655.0
SHD3_k127_3320059_60 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000000000006347 68.0
SHD3_k127_3320059_61 Tetratricopeptide repeat - - - 0.000000009302 68.0
SHD3_k127_3320059_63 - - - - 0.000001831 55.0
SHD3_k127_3320059_64 PFAM DsrE DsrF-like family - - - 0.000002597 53.0
SHD3_k127_3320059_65 PKD domain - - - 0.000361 53.0
SHD3_k127_3320059_7 Endoribonuclease that initiates mRNA decay K18682 - - 1.516e-208 664.0
SHD3_k127_3320059_8 Proton-conducting membrane transporter K00342 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 6.66e-199 635.0
SHD3_k127_3320059_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 609.0
SHD3_k127_3321802_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 498.0
SHD3_k127_3321802_1 NOG31153 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008469 284.0
SHD3_k127_3321802_2 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009411 269.0
SHD3_k127_3321802_3 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000001382 147.0
SHD3_k127_3321802_4 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.0000000000000000000000000000001192 127.0
SHD3_k127_3349413_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 3.654e-278 886.0
SHD3_k127_3349413_1 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000001737 158.0
SHD3_k127_3349413_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000004267 73.0
SHD3_k127_3349413_3 SurA N-terminal domain K03769 - 5.2.1.8 0.00000583 57.0
SHD3_k127_3350419_1 Domain of unknown function (DUF4126) - - - 0.0000000001979 62.0
SHD3_k127_3394952_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 7.736e-196 675.0
SHD3_k127_3394952_1 Prokaryotic N-terminal methylation motif - - - 0.0000002329 56.0
SHD3_k127_3427382_0 PFAM Type II secretion system protein E K02454 - - 5.186e-199 631.0
SHD3_k127_3427382_1 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 528.0
SHD3_k127_3427382_2 PFAM Phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 386.0
SHD3_k127_3427382_3 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 300.0
SHD3_k127_3427382_4 SMART Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000000004269 204.0
SHD3_k127_3427382_5 protein transport across the cell outer membrane K02452,K02463 - - 0.00000000000000000000000000000000000003915 154.0
SHD3_k127_3427382_6 SMART Rhodanese domain protein - - - 0.0000000000000000005432 90.0
SHD3_k127_3439223_0 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 484.0
SHD3_k127_3439279_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 4.082e-225 704.0
SHD3_k127_3439279_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 387.0
SHD3_k127_3439279_10 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.00000000000000000000000000000000001116 145.0
SHD3_k127_3439279_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.00000000000000000000000000000005369 131.0
SHD3_k127_3439279_12 - - - - 0.0000000000000000000000000004854 119.0
SHD3_k127_3439279_13 Protein of unknown function DUF134 - - - 0.000000000000000000000000011 111.0
SHD3_k127_3439279_14 Antioxidant, AhpC TSA family - - - 0.0000000000005983 72.0
SHD3_k127_3439279_16 Thioredoxin-like - - - 0.0001427 48.0
SHD3_k127_3439279_2 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 368.0
SHD3_k127_3439279_3 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 288.0
SHD3_k127_3439279_4 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000743 279.0
SHD3_k127_3439279_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000005933 245.0
SHD3_k127_3439279_6 ATP cone domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000009758 243.0
SHD3_k127_3439279_7 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000001156 198.0
SHD3_k127_3439279_8 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000000000001205 153.0
SHD3_k127_3439279_9 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000000000007821 140.0
SHD3_k127_344711_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.268e-247 776.0
SHD3_k127_344711_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 587.0
SHD3_k127_344711_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 385.0
SHD3_k127_3462367_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000001771 150.0
SHD3_k127_3463018_0 PFAM ATP adenylyltransferase K00988 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000000004682 252.0
SHD3_k127_3463018_1 - - - - 0.0000002889 53.0
SHD3_k127_347124_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1062.0
SHD3_k127_34746_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 595.0
SHD3_k127_34746_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 394.0
SHD3_k127_34746_2 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004621 254.0
SHD3_k127_34746_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000006289 222.0
SHD3_k127_3511738_0 PFAM glucose-methanol-choline oxidoreductase K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 332.0
SHD3_k127_3555959_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 431.0
SHD3_k127_3582702_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000622 242.0
SHD3_k127_3582702_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000002492 209.0
SHD3_k127_3582702_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000004676 190.0
SHD3_k127_3582702_3 Peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000496 178.0
SHD3_k127_3584665_0 Flavin-binding monooxygenase-like K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000003432 237.0
SHD3_k127_3584665_1 SnoaL-like polyketide cyclase - - - 0.0000000000000002846 84.0
SHD3_k127_3584665_2 SPTR A9B8L4 Integrase catalytic region - - - 0.00000000000000796 87.0
SHD3_k127_3588700_0 Glyoxalase-like domain K01759,K08234 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000001027 202.0
SHD3_k127_3588700_1 - - - - 0.00000000000000000000000000000000000000000009659 162.0
SHD3_k127_3588700_2 Scavenger mRNA decapping enzyme C-term binding - - - 0.000000000000000072 84.0
SHD3_k127_3594401_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 2.356e-280 885.0
SHD3_k127_3594401_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 584.0
SHD3_k127_3594401_2 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 417.0
SHD3_k127_3594401_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 352.0
SHD3_k127_3594401_4 PFAM Cytochrome b5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 298.0
SHD3_k127_3594401_5 PFAM ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001634 234.0
SHD3_k127_3594401_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.00000000000261 68.0
SHD3_k127_3612669_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000000000000000000000000000000000000000005489 159.0
SHD3_k127_3612669_1 peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.00000000000001805 84.0
SHD3_k127_3616308_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.059e-229 739.0
SHD3_k127_3616308_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 617.0
SHD3_k127_3616308_10 lactate metabolic process K11473,K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000001262 246.0
SHD3_k127_3616308_11 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000007875 237.0
SHD3_k127_3616308_12 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000004572 231.0
SHD3_k127_3616308_13 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000002787 175.0
SHD3_k127_3616308_14 NlpC/P60 family K20742 - 3.4.14.13 0.00000000000000000000000000000000000279 151.0
SHD3_k127_3616308_15 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000007236 132.0
SHD3_k127_3616308_16 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000315 124.0
SHD3_k127_3616308_17 - - - - 0.000000000004254 67.0
SHD3_k127_3616308_18 PFAM amino acid-binding ACT domain protein - - - 0.0000000001452 67.0
SHD3_k127_3616308_19 Domain of unknown function (DUF4912) K09942 - - 0.00000008952 63.0
SHD3_k127_3616308_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 594.0
SHD3_k127_3616308_20 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00006526 55.0
SHD3_k127_3616308_21 peptidyl-prolyl isomerase K07533 - 5.2.1.8 0.0007971 52.0
SHD3_k127_3616308_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 451.0
SHD3_k127_3616308_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 378.0
SHD3_k127_3616308_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 357.0
SHD3_k127_3616308_6 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 340.0
SHD3_k127_3616308_7 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 305.0
SHD3_k127_3616308_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 293.0
SHD3_k127_3616308_9 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003839 275.0
SHD3_k127_3619880_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000002329 184.0
SHD3_k127_3619880_1 - - - - 0.000001647 58.0
SHD3_k127_3625146_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 539.0
SHD3_k127_3625146_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000001161 258.0
SHD3_k127_3625146_2 4Fe-4S binding domain - - - 0.000000000000001234 78.0
SHD3_k127_3625146_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000002828 72.0
SHD3_k127_3625146_4 Cupin domain - - - 0.000000002986 61.0
SHD3_k127_3627723_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 332.0
SHD3_k127_3627723_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005554 278.0
SHD3_k127_3627723_10 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001906 105.0
SHD3_k127_3627723_11 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001368 94.0
SHD3_k127_3627723_12 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000001063 74.0
SHD3_k127_3627723_2 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000008933 229.0
SHD3_k127_3627723_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001658 231.0
SHD3_k127_3627723_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000009454 205.0
SHD3_k127_3627723_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000005801 201.0
SHD3_k127_3627723_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000001804 154.0
SHD3_k127_3627723_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000009098 141.0
SHD3_k127_3627723_8 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000001207 133.0
SHD3_k127_3627723_9 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000001897 111.0
SHD3_k127_3631876_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1056.0
SHD3_k127_3631876_1 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 379.0
SHD3_k127_3631876_2 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004374 271.0
SHD3_k127_3631876_3 endonuclease III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001141 255.0
SHD3_k127_3631876_4 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000001307 169.0
SHD3_k127_3631876_5 translation release factor activity - - - 0.000000000000000000000000000000000000000325 153.0
SHD3_k127_3631876_6 1,4-alpha-glucan branching enzyme activity - - - 0.000000000000000000000000000001295 127.0
SHD3_k127_3631876_7 SMART Cold shock protein K03704 - - 0.000000000000000000000001952 103.0
SHD3_k127_3631876_8 - - - - 0.000000007235 59.0
SHD3_k127_36334_0 Belongs to the catalase family K03781 - 1.11.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 440.0
SHD3_k127_36334_1 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 336.0
SHD3_k127_36334_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003198 244.0
SHD3_k127_36334_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000008385 136.0
SHD3_k127_36334_4 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000008079 87.0
SHD3_k127_36334_5 Aldo/keto reductase family - - - 0.00004046 47.0
SHD3_k127_3635608_0 - - - - 0.0000000000000000000000000009672 113.0
SHD3_k127_3635608_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000001942 69.0
SHD3_k127_3637843_0 IS30 family K07482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 381.0
SHD3_k127_3639962_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2108.0
SHD3_k127_3639962_1 Surface antigen K07277 - - 1.954e-260 824.0
SHD3_k127_3639962_10 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000004117 205.0
SHD3_k127_3639962_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000009633 212.0
SHD3_k127_3639962_12 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000004536 187.0
SHD3_k127_3639962_13 denitrification pathway - - - 0.0000000000000000000000000000000000000003257 161.0
SHD3_k127_3639962_14 12 heme-binding sites - - - 0.00000000000000000000000000000000000004504 153.0
SHD3_k127_3639962_15 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000003657 128.0
SHD3_k127_3639962_16 protein kinase activity - - - 0.000000000000000000000000008558 118.0
SHD3_k127_3639962_17 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000004758 102.0
SHD3_k127_3639962_18 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000008385 50.0
SHD3_k127_3639962_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 580.0
SHD3_k127_3639962_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 442.0
SHD3_k127_3639962_4 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 428.0
SHD3_k127_3639962_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 390.0
SHD3_k127_3639962_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 364.0
SHD3_k127_3639962_7 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 286.0
SHD3_k127_3639962_8 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001221 257.0
SHD3_k127_3639962_9 Psort location Cytoplasmic, score 8.96 K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000033 254.0
SHD3_k127_36418_0 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 392.0
SHD3_k127_36418_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 354.0
SHD3_k127_36418_2 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000004243 158.0
SHD3_k127_3646649_1 GYD domain - - - 0.0000000000000000000007142 101.0
SHD3_k127_3647169_0 Chain length determinant protein K16554 - - 1.981e-208 671.0
SHD3_k127_3647169_1 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 564.0
SHD3_k127_3647169_10 - - - - 0.000000005053 57.0
SHD3_k127_3647169_11 Belongs to the peptidase S26 family K13280 - 3.4.21.89 0.00000004384 64.0
SHD3_k127_3647169_12 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000004075 55.0
SHD3_k127_3647169_2 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 302.0
SHD3_k127_3647169_3 export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007596 284.0
SHD3_k127_3647169_4 Putative beta-barrel porin 2 K20920 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001476 285.0
SHD3_k127_3647169_5 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000005662 243.0
SHD3_k127_3647169_6 protein-disulfide reductase activity - - - 0.00000000000000000000000006387 112.0
SHD3_k127_3647169_8 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000004254 110.0
SHD3_k127_3647169_9 FHA domain - - - 0.00000000001032 76.0
SHD3_k127_3648879_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000002404 136.0
SHD3_k127_3648879_1 CsbD-like - - - 0.00000000000000000003794 93.0
SHD3_k127_3648879_2 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000007934 72.0
SHD3_k127_3648879_3 Putative regulatory protein - - - 0.000000003931 61.0
SHD3_k127_3653101_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 592.0
SHD3_k127_3653101_1 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 577.0
SHD3_k127_3653101_10 glycosyl transferase family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004823 249.0
SHD3_k127_3653101_11 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000000000004773 179.0
SHD3_k127_3653101_12 nucleotidyltransferase activity K07076 - - 0.000000000000000000000000000008882 124.0
SHD3_k127_3653101_13 Uncharacterized conserved protein (DUF2304) - - - 0.00000000000000000007335 93.0
SHD3_k127_3653101_14 PFAM glycosyl transferase group 1 - - - 0.000002439 51.0
SHD3_k127_3653101_15 Response regulator receiver - - - 0.00002168 55.0
SHD3_k127_3653101_16 Trypsin-like peptidase domain - - - 0.00004628 57.0
SHD3_k127_3653101_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 510.0
SHD3_k127_3653101_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 503.0
SHD3_k127_3653101_4 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 487.0
SHD3_k127_3653101_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 428.0
SHD3_k127_3653101_6 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 397.0
SHD3_k127_3653101_7 Glycosyl transferase family group 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 318.0
SHD3_k127_3653101_8 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008954 282.0
SHD3_k127_3653101_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000503 278.0
SHD3_k127_3666375_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 398.0
SHD3_k127_3666375_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 395.0
SHD3_k127_3666567_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 318.0
SHD3_k127_3666567_1 histidine kinase-, DNA gyrase B - - - 0.0001021 52.0
SHD3_k127_3674103_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.245e-211 668.0
SHD3_k127_3674103_1 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000502 120.0
SHD3_k127_3674103_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000002462 113.0
SHD3_k127_3674103_3 TIGRFAM cysteine K12339 - 2.5.1.47 0.000000000000000000000000008898 110.0
SHD3_k127_3674103_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000004374 102.0
SHD3_k127_3674149_0 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005105 289.0
SHD3_k127_3674149_1 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006826 265.0
SHD3_k127_3674914_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.59e-257 811.0
SHD3_k127_3674914_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 3.536e-228 721.0
SHD3_k127_3674914_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 317.0
SHD3_k127_3674914_11 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000154 253.0
SHD3_k127_3674914_12 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000003051 225.0
SHD3_k127_3674914_13 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000886 227.0
SHD3_k127_3674914_14 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000006087 227.0
SHD3_k127_3674914_15 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000006718 205.0
SHD3_k127_3674914_16 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000001208 162.0
SHD3_k127_3674914_17 Glu-tRNAGln amidotransferase C subunit K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000002258 110.0
SHD3_k127_3674914_18 nucleotidyltransferase activity K07075 - - 0.000000000000000000000001022 111.0
SHD3_k127_3674914_19 - - - - 0.0000000000000000000006546 100.0
SHD3_k127_3674914_2 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 5.101e-209 661.0
SHD3_k127_3674914_20 Domain of unknown function (DUF1858) - - - 0.0000000000000000005184 88.0
SHD3_k127_3674914_23 4Fe-4S binding domain - - - 0.000005825 50.0
SHD3_k127_3674914_3 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 537.0
SHD3_k127_3674914_4 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 508.0
SHD3_k127_3674914_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 434.0
SHD3_k127_3674914_6 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 402.0
SHD3_k127_3674914_7 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 381.0
SHD3_k127_3674914_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 355.0
SHD3_k127_3674914_9 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 348.0
SHD3_k127_3677979_0 eight transmembrane protein EpsH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006186 245.0
SHD3_k127_3677979_1 Protein of unknown function (DUF3485) - - - 0.00000000000000000000000000000000000003442 151.0
SHD3_k127_3682607_0 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 293.0
SHD3_k127_3682607_1 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002703 242.0
SHD3_k127_36837_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 6.436e-208 655.0
SHD3_k127_36837_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 570.0
SHD3_k127_36837_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 487.0
SHD3_k127_36837_3 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 368.0
SHD3_k127_36837_4 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 355.0
SHD3_k127_36837_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006102 276.0
SHD3_k127_36837_6 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000002373 234.0
SHD3_k127_36837_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000007069 232.0
SHD3_k127_36837_8 PFAM phosphoesterase RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000106 238.0
SHD3_k127_3683932_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 359.0
SHD3_k127_3683932_1 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 295.0
SHD3_k127_3683932_2 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000004125 189.0
SHD3_k127_3683932_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000231 136.0
SHD3_k127_3683932_4 toxin-antitoxin pair type II binding - - - 0.000000000000000000001226 97.0
SHD3_k127_3687148_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000219 260.0
SHD3_k127_3687148_1 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000003431 169.0
SHD3_k127_3695889_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 342.0
SHD3_k127_3695889_1 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 325.0
SHD3_k127_3695889_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.0000000000000000000000007279 106.0
SHD3_k127_3696591_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 5.077e-262 820.0
SHD3_k127_3696591_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 578.0
SHD3_k127_3696591_10 SdpI/YhfL protein family - - - 0.0000000000000000000000008075 106.0
SHD3_k127_3696591_11 DRTGG domain - - - 0.00000000000000002416 85.0
SHD3_k127_3696591_2 response regulator K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 495.0
SHD3_k127_3696591_3 histidine kinase, HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 346.0
SHD3_k127_3696591_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.000000000000000000000000000000000000000000000001869 185.0
SHD3_k127_3696591_5 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000007193 155.0
SHD3_k127_3696591_6 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000002045 145.0
SHD3_k127_3696591_7 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000508 134.0
SHD3_k127_3696591_8 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000001361 119.0
SHD3_k127_3696591_9 DRTGG domain protein - - - 0.00000000000000000000000001631 112.0
SHD3_k127_370277_0 Pectate lyase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009933 297.0
SHD3_k127_370277_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000002438 141.0
SHD3_k127_3709437_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 8.093e-242 760.0
SHD3_k127_3709437_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 441.0
SHD3_k127_3709437_10 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.000000000000000000000000000000000000000000000000002445 190.0
SHD3_k127_3709437_11 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000001798 185.0
SHD3_k127_3709437_12 Transcriptional regulator - - - 0.0000000000000000000000000000000000000007789 153.0
SHD3_k127_3709437_13 Sulfurtransferase TusA - - - 0.000000000000000000000003548 104.0
SHD3_k127_3709437_14 - - - - 0.000000000000000000004668 96.0
SHD3_k127_3709437_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 415.0
SHD3_k127_3709437_3 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 377.0
SHD3_k127_3709437_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 329.0
SHD3_k127_3709437_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 325.0
SHD3_k127_3709437_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001302 275.0
SHD3_k127_3709437_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000002861 232.0
SHD3_k127_3709437_8 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000007249 237.0
SHD3_k127_3709437_9 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000006648 192.0
SHD3_k127_3711121_0 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000001918 218.0
SHD3_k127_3734967_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 6.901e-200 652.0
SHD3_k127_3734967_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 451.0
SHD3_k127_3734967_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 430.0
SHD3_k127_3734967_3 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 414.0
SHD3_k127_3734967_4 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 351.0
SHD3_k127_3734967_5 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000000004338 179.0
SHD3_k127_3734967_6 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000003917 166.0
SHD3_k127_3734967_7 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000003889 130.0
SHD3_k127_3734967_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000005244 69.0
SHD3_k127_3739869_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 6.481e-194 620.0
SHD3_k127_3739869_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 564.0
SHD3_k127_3739869_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 366.0
SHD3_k127_3739869_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 326.0
SHD3_k127_3739869_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008687 313.0
SHD3_k127_3739869_13 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004943 275.0
SHD3_k127_3739869_14 phosphatidate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003612 263.0
SHD3_k127_3739869_15 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001112 262.0
SHD3_k127_3739869_16 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004214 247.0
SHD3_k127_3739869_17 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000003672 241.0
SHD3_k127_3739869_18 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000009864 222.0
SHD3_k127_3739869_19 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000005506 175.0
SHD3_k127_3739869_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 525.0
SHD3_k127_3739869_20 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000007078 173.0
SHD3_k127_3739869_21 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000001192 151.0
SHD3_k127_3739869_22 RNA-binding protein containing a PIN domain K06962 - - 0.000000000000000000000000000000001181 135.0
SHD3_k127_3739869_23 - - - - 0.0000000000000000000000000001074 119.0
SHD3_k127_3739869_24 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000002829 113.0
SHD3_k127_3739869_25 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000001942 107.0
SHD3_k127_3739869_26 Belongs to the UPF0235 family K09131 - - 0.000000000000003262 78.0
SHD3_k127_3739869_27 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000002026 73.0
SHD3_k127_3739869_28 cell division protein FtsQ K03589 - - 0.0000000000008981 78.0
SHD3_k127_3739869_29 PFAM pyridoxamine 5-phosphate - - - 0.00000006154 56.0
SHD3_k127_3739869_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 460.0
SHD3_k127_3739869_31 Protein of unknown function (DUF861) K06995 - - 0.00002443 47.0
SHD3_k127_3739869_32 Evidence 5 No homology to any previously reported sequences - - - 0.0001933 51.0
SHD3_k127_3739869_4 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 458.0
SHD3_k127_3739869_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 419.0
SHD3_k127_3739869_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 407.0
SHD3_k127_3739869_7 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 394.0
SHD3_k127_3739869_8 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 379.0
SHD3_k127_3739869_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 368.0
SHD3_k127_3748776_0 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 519.0
SHD3_k127_3748776_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 396.0
SHD3_k127_3748776_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 397.0
SHD3_k127_3748776_3 membrane K09133 - - 0.0000000000000000000000000000000000004321 144.0
SHD3_k127_3757001_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 503.0
SHD3_k127_3757001_2 MgtC SapB transporter K07507 - - 0.00000000000000698 75.0
SHD3_k127_3757001_3 PFAM blue (type 1) copper domain protein - - - 0.0000000000001493 80.0
SHD3_k127_3757001_4 PIN domain - - - 0.00000000009615 68.0
SHD3_k127_3757001_5 - - - - 0.0000000004608 65.0
SHD3_k127_3775744_0 metal-dependent phosphohydrolase HD - - - 2.992e-207 664.0
SHD3_k127_3775744_1 type IV pilus assembly PilZ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 510.0
SHD3_k127_3775744_2 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 405.0
SHD3_k127_3775744_3 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 288.0
SHD3_k127_3789309_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 391.0
SHD3_k127_3789309_1 Amidohydrolase family K01465,K01466 - 3.5.2.3,3.5.2.5 0.0000000000000000000000000000000000000000001244 164.0
SHD3_k127_3789451_0 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 335.0
SHD3_k127_3789451_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006158 279.0
SHD3_k127_3789451_2 Outer membrane efflux protein K18903 - - 0.000000000000000000000000000000000000000000000000000000151 198.0
SHD3_k127_3789451_3 - - - - 0.000000000000000000000000000000000000000000000003864 178.0
SHD3_k127_3789451_4 Uncharacterized ACR, COG1678 - - - 0.000000000000000000000000000000000000857 148.0
SHD3_k127_3807265_0 - - - - 0.000004304 54.0
SHD3_k127_3810120_0 Acyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 557.0
SHD3_k127_3811403_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1105.0
SHD3_k127_3811403_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.637e-229 713.0
SHD3_k127_3811403_2 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 610.0
SHD3_k127_3811403_3 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 571.0
SHD3_k127_3811403_4 HD domain K07023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001734 278.0
SHD3_k127_3811403_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000002736 243.0
SHD3_k127_3811403_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000002104 213.0
SHD3_k127_3826473_0 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 338.0
SHD3_k127_3826473_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000366 63.0
SHD3_k127_3845884_0 Glycosyltransferase WbsX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 399.0
SHD3_k127_3845884_1 Glycosyltransferase like family K20444 - - 0.0000000000000000000000000000000000000006248 156.0
SHD3_k127_3859054_0 glycosyl transferase group 1 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 401.0
SHD3_k127_3859054_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 355.0
SHD3_k127_3859054_10 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000003236 169.0
SHD3_k127_3859054_11 PFAM Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000002265 163.0
SHD3_k127_3859054_13 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000004653 161.0
SHD3_k127_3859054_14 Bacterial transferase hexapeptide (six repeats) K18234 - - 0.00000000000000000000000000000000000007287 149.0
SHD3_k127_3859054_15 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.0000000000000000000000000000000178 145.0
SHD3_k127_3859054_16 VanZ like family - - - 0.0000000000000000000000000002174 121.0
SHD3_k127_3859054_17 - - - - 0.0000000000000002724 94.0
SHD3_k127_3859054_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11356 - 2.7.13.3 0.0005102 43.0
SHD3_k127_3859054_2 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 332.0
SHD3_k127_3859054_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 317.0
SHD3_k127_3859054_4 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 319.0
SHD3_k127_3859054_5 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 308.0
SHD3_k127_3859054_6 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008732 293.0
SHD3_k127_3859054_7 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007732 243.0
SHD3_k127_3859054_8 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002375 244.0
SHD3_k127_3859054_9 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000006501 196.0
SHD3_k127_3887327_0 von Willebrand factor, type A K07114 - - 1.547e-312 974.0
SHD3_k127_3887327_1 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 493.0
SHD3_k127_3887327_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 395.0
SHD3_k127_3887327_3 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 352.0
SHD3_k127_3887327_4 Putative Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 333.0
SHD3_k127_3887327_5 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000006904 230.0
SHD3_k127_3887327_6 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000001024 203.0
SHD3_k127_3887327_7 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000388 113.0
SHD3_k127_3889365_0 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000003154 152.0
SHD3_k127_3908863_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 317.0
SHD3_k127_3908863_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001091 269.0
SHD3_k127_3908863_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000004006 91.0
SHD3_k127_391323_0 - - - - 0.0000000006944 63.0
SHD3_k127_391323_1 ORF located using Blastx - - - 0.0001414 46.0
SHD3_k127_391323_2 - - - - 0.0003688 44.0
SHD3_k127_391323_3 - - - - 0.0009165 42.0
SHD3_k127_3913542_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001295 267.0
SHD3_k127_3913542_1 Transposase - - - 0.0000000000000000000000001088 108.0
SHD3_k127_3935604_0 cellulase activity K07451,K17713 - - 0.000000000000000003912 100.0
SHD3_k127_3935604_1 - - - - 0.00000001261 65.0
SHD3_k127_3935604_2 amine dehydrogenase activity K01179,K03333,K12287 - 1.1.3.6,3.2.1.4 0.0000001061 66.0
SHD3_k127_3936817_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 3.992e-311 960.0
SHD3_k127_3936817_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.834e-244 765.0
SHD3_k127_3936817_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 420.0
SHD3_k127_3936817_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 370.0
SHD3_k127_3936817_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000003442 250.0
SHD3_k127_3942372_0 PFAM nickel-dependent hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 598.0
SHD3_k127_3942372_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 464.0
SHD3_k127_3942372_10 cheY-homologous receiver domain - - - 0.000000000000003545 85.0
SHD3_k127_3942372_11 Universal stress protein family - - - 0.00000000003119 71.0
SHD3_k127_3942372_12 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000003034 64.0
SHD3_k127_3942372_13 - - - - 0.0000001195 63.0
SHD3_k127_3942372_14 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000021 57.0
SHD3_k127_3942372_2 PFAM Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 432.0
SHD3_k127_3942372_3 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 406.0
SHD3_k127_3942372_4 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 361.0
SHD3_k127_3942372_5 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000001651 206.0
SHD3_k127_3942372_6 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000003202 168.0
SHD3_k127_3942372_7 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.0000000000000000000000000003727 118.0
SHD3_k127_3942372_8 Cytochrome c K08738 - - 0.000000000000000000000004509 106.0
SHD3_k127_3942372_9 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000008235 107.0
SHD3_k127_3946003_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 429.0
SHD3_k127_3946897_0 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000003759 243.0
SHD3_k127_3946897_1 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.00000000000000000000000000007504 116.0
SHD3_k127_3946897_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.00000000000000000000000001242 113.0
SHD3_k127_3946897_3 oxidase, subunit IV K02277 - 1.9.3.1 0.000000000000287 73.0
SHD3_k127_3958978_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.553e-262 818.0
SHD3_k127_3958978_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000001216 134.0
SHD3_k127_396606_0 General secretory system II, protein E domain protein K02652 - - 2.353e-217 691.0
SHD3_k127_396606_1 FAD binding domain K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 625.0
SHD3_k127_396606_10 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 349.0
SHD3_k127_396606_11 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 336.0
SHD3_k127_396606_12 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 336.0
SHD3_k127_396606_13 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 323.0
SHD3_k127_396606_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002001 279.0
SHD3_k127_396606_15 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000001542 209.0
SHD3_k127_396606_16 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000002268 195.0
SHD3_k127_396606_17 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000001608 184.0
SHD3_k127_396606_18 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 - - 0.0000000000000000000000000000000000000000000348 174.0
SHD3_k127_396606_19 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000009486 152.0
SHD3_k127_396606_2 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 546.0
SHD3_k127_396606_20 response to copper ion K07156,K14166 - - 0.000000000000000000000000000000007845 131.0
SHD3_k127_396606_21 NosL - - - 0.0000000000000000000000000000003813 140.0
SHD3_k127_396606_22 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000000000004383 117.0
SHD3_k127_396606_23 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000002645 100.0
SHD3_k127_396606_24 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000007125 91.0
SHD3_k127_396606_25 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000001483 88.0
SHD3_k127_396606_26 Universal stress protein family - - - 0.00000000000001462 85.0
SHD3_k127_396606_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 548.0
SHD3_k127_396606_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 526.0
SHD3_k127_396606_5 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 476.0
SHD3_k127_396606_6 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 477.0
SHD3_k127_396606_7 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 467.0
SHD3_k127_396606_8 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 402.0
SHD3_k127_396606_9 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 378.0
SHD3_k127_3969213_0 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 0.0 1073.0
SHD3_k127_3969213_1 Protein of unknown function, DUF255 K06888 - - 2.124e-254 800.0
SHD3_k127_3969213_10 Mur ligase family, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 313.0
SHD3_k127_3969213_11 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 285.0
SHD3_k127_3969213_12 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001877 282.0
SHD3_k127_3969213_13 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003758 284.0
SHD3_k127_3969213_14 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000003025 238.0
SHD3_k127_3969213_15 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000002003 223.0
SHD3_k127_3969213_16 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000008982 213.0
SHD3_k127_3969213_17 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000001732 221.0
SHD3_k127_3969213_18 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000004913 206.0
SHD3_k127_3969213_19 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000000002367 197.0
SHD3_k127_3969213_2 Domain in cystathionine beta-synthase and other proteins. K07182 - - 8.356e-198 635.0
SHD3_k127_3969213_20 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000147 172.0
SHD3_k127_3969213_21 methyltransferase activity - - - 0.00000000000000000000000000000000000000007001 157.0
SHD3_k127_3969213_22 nucleotide metabolic process - - - 0.000000000000000000000000000000000000002268 155.0
SHD3_k127_3969213_23 NAD dependent epimerase dehydratase family protein - - - 0.00000000000000000000000000000001051 139.0
SHD3_k127_3969213_24 - - - - 0.00000000000000000000000000000005802 128.0
SHD3_k127_3969213_27 Response regulator receiver - - - 0.000000000000000000000000004455 115.0
SHD3_k127_3969213_28 Cold shock K03704 - - 0.00000000000000000000000003491 108.0
SHD3_k127_3969213_29 Transcriptional regulator - - - 0.00000000000000000000002532 103.0
SHD3_k127_3969213_3 PFAM natural resistance-associated macrophage protein K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 518.0
SHD3_k127_3969213_30 Predicted membrane protein (DUF2318) - - - 0.0000000000000000002048 93.0
SHD3_k127_3969213_31 - - - - 0.0000000000000000007644 92.0
SHD3_k127_3969213_32 Homologous to orf229 gp Streptococcus thermophilus bacteriophage Sfi19 gi 9632919 ref NP_049948.1 - - - 0.000000000000000008735 89.0
SHD3_k127_3969213_33 Transposase - - - 0.00000000000000004315 81.0
SHD3_k127_3969213_35 - - - - 0.00000000000001646 75.0
SHD3_k127_3969213_36 peroxiredoxin activity - - - 0.000007146 49.0
SHD3_k127_3969213_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 499.0
SHD3_k127_3969213_5 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 490.0
SHD3_k127_3969213_6 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009592 443.0
SHD3_k127_3969213_7 PFAM peptidase K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 408.0
SHD3_k127_3969213_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 361.0
SHD3_k127_3969213_9 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 336.0
SHD3_k127_3978875_0 - - - - 0.0000000000000000000003948 111.0
SHD3_k127_3978875_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0000000000000008756 78.0
SHD3_k127_3992889_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 479.0
SHD3_k127_3992889_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 431.0
SHD3_k127_3992889_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 389.0
SHD3_k127_3992889_3 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 380.0
SHD3_k127_3992889_4 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001715 271.0
SHD3_k127_3992889_5 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000001212 106.0
SHD3_k127_3992889_6 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000009463 92.0
SHD3_k127_4019000_0 peptidyl-prolyl isomerase K07533 - 5.2.1.8 0.0000000005123 68.0
SHD3_k127_4019954_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000003354 166.0
SHD3_k127_4019954_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000001374 158.0
SHD3_k127_4027344_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 396.0
SHD3_k127_4027344_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009383 240.0
SHD3_k127_4027344_2 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.00000000000000000000000000000000006755 133.0
SHD3_k127_40837_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 427.0
SHD3_k127_40837_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 388.0
SHD3_k127_40837_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 358.0
SHD3_k127_40837_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 319.0
SHD3_k127_40837_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 310.0
SHD3_k127_40837_5 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 298.0
SHD3_k127_40837_6 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000008609 176.0
SHD3_k127_40837_7 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000003721 171.0
SHD3_k127_40837_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000005488 153.0
SHD3_k127_40837_9 Putative zinc-finger - - - 0.0000007522 57.0
SHD3_k127_4122938_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 5.911e-217 681.0
SHD3_k127_424186_0 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 532.0
SHD3_k127_424186_1 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 515.0
SHD3_k127_424186_10 Transcription factor zinc-finger - - - 0.00000000000000000001051 100.0
SHD3_k127_424186_11 PAS fold - - - 0.00001756 47.0
SHD3_k127_424186_2 Phosphonate ABC transporter, periplasmic K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 352.0
SHD3_k127_424186_3 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001866 263.0
SHD3_k127_424186_4 Pas domain s-box - - - 0.000000000000000000000000000000000000000000000000000000000000000000003249 256.0
SHD3_k127_424186_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008427 241.0
SHD3_k127_424186_6 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000007944 167.0
SHD3_k127_424186_7 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000007043 162.0
SHD3_k127_424186_9 Phosphoribosyl-AMP cyclohydrolase K01496,K01497,K01523,K01814,K11755 GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 0.0000000000000000000000004278 107.0
SHD3_k127_425832_0 regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000002132 194.0
SHD3_k127_425832_1 Trypsin - - - 0.000000000000000000000000000000000000000003671 163.0
SHD3_k127_42585_0 acetyltransferase - - - 1.404e-197 620.0
SHD3_k127_42585_1 - - - - 0.0000000000000000000000000001297 117.0
SHD3_k127_4294631_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 551.0
SHD3_k127_4294631_1 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000007836 184.0
SHD3_k127_4296656_0 reductase, alpha subunit K00394 - 1.8.99.2 5.796e-262 814.0
SHD3_k127_4296656_1 reductase, beta subunit K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000009973 224.0
SHD3_k127_4303869_0 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 470.0
SHD3_k127_4303869_1 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 290.0
SHD3_k127_4303869_2 Radical SAM K22227 - - 0.0000000000000000000001732 108.0
SHD3_k127_4303869_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000003219 92.0
SHD3_k127_4303869_4 Methyltransferase domain - - - 0.000007692 57.0
SHD3_k127_4305400_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 483.0
SHD3_k127_4314721_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 505.0
SHD3_k127_4314721_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 462.0
SHD3_k127_4314721_10 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000009635 168.0
SHD3_k127_4314721_11 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.000000000000000000000000000000000000000000001369 171.0
SHD3_k127_4314721_12 Histidine kinase A domain protein K01768 - 4.6.1.1 0.000000000000000000000000000000000000000005625 166.0
SHD3_k127_4314721_13 COG2203 FOG GAF domain - - - 0.000004338 58.0
SHD3_k127_4314721_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 426.0
SHD3_k127_4314721_3 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 297.0
SHD3_k127_4314721_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009582 252.0
SHD3_k127_4314721_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001491 257.0
SHD3_k127_4314721_6 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003146 248.0
SHD3_k127_4314721_7 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000001843 223.0
SHD3_k127_4314721_8 - - - - 0.0000000000000000000000000000000000000000000000000000000001977 210.0
SHD3_k127_4314721_9 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000004426 179.0
SHD3_k127_4314974_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000002897 228.0
SHD3_k127_4314974_1 Putative zinc-finger - - - 0.00000000000000000000000000005618 129.0
SHD3_k127_4316294_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 384.0
SHD3_k127_4316294_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 333.0
SHD3_k127_4316294_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002959 282.0
SHD3_k127_4316294_3 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000001332 228.0
SHD3_k127_4316294_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000002094 167.0
SHD3_k127_4316294_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000003395 153.0
SHD3_k127_4316294_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000001965 134.0
SHD3_k127_4316294_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000004898 102.0
SHD3_k127_4316294_8 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001528 99.0
SHD3_k127_4316294_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000266 84.0
SHD3_k127_4318903_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000104 283.0
SHD3_k127_4318903_1 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000001971 129.0
SHD3_k127_43192_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 354.0
SHD3_k127_43192_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 314.0
SHD3_k127_43192_2 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000003092 127.0
SHD3_k127_43192_3 Domain of unknown function (DUF4382) - - - 0.0000000000000000002048 93.0
SHD3_k127_43192_4 Cupin domain - - - 0.00000000001324 64.0
SHD3_k127_43192_5 Domain of unknown function (DUF4382) - - - 0.0001233 46.0
SHD3_k127_4323317_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 571.0
SHD3_k127_4323317_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 387.0
SHD3_k127_4323317_2 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 347.0
SHD3_k127_4323317_3 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 288.0
SHD3_k127_4323317_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 286.0
SHD3_k127_4323317_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001039 266.0
SHD3_k127_4323317_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000002647 215.0
SHD3_k127_4323317_7 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000008551 237.0
SHD3_k127_4323317_8 Belongs to the peptidase M48B family - - - 0.00000001974 58.0
SHD3_k127_4323676_0 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 602.0
SHD3_k127_4323676_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000004774 55.0
SHD3_k127_4326799_0 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000002324 193.0
SHD3_k127_4326799_2 Translation initiation factor SUI1 - - - 0.000005166 48.0
SHD3_k127_4329739_0 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.0000000000000000000000000000000000000000000000000000000000000000583 226.0
SHD3_k127_4329739_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000004379 200.0
SHD3_k127_4329739_2 - - - - 0.0000006412 57.0
SHD3_k127_4329739_3 - - - - 0.00001681 50.0
SHD3_k127_4329739_4 PFAM Cupin 2 conserved barrel domain protein - - - 0.00005419 51.0
SHD3_k127_4339609_0 - - - - 0.000000000000000000000000003271 111.0
SHD3_k127_4339609_3 - - - - 0.0000001598 52.0
SHD3_k127_4344870_0 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000007173 75.0
SHD3_k127_4344870_1 chlorophyll binding K03286,K03640 - - 0.00000001221 61.0
SHD3_k127_4360628_0 reductase, alpha subunit K00394 - 1.8.99.2 1.122e-255 796.0
SHD3_k127_4360628_1 FAD dependent oxidoreductase K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 594.0
SHD3_k127_4364476_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 553.0
SHD3_k127_4364476_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 484.0
SHD3_k127_4364476_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 417.0
SHD3_k127_4364476_3 pfam abc K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 355.0
SHD3_k127_4364476_4 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 299.0
SHD3_k127_4370263_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 2.084e-245 762.0
SHD3_k127_4373081_0 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000001199 181.0
SHD3_k127_4373081_1 Glutathione peroxidase - - - 0.0000000000000000000000000000000002999 137.0
SHD3_k127_4373081_2 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000008648 120.0
SHD3_k127_4375353_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 432.0
SHD3_k127_4375353_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 409.0
SHD3_k127_4375353_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000003535 261.0
SHD3_k127_4375353_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000005332 201.0
SHD3_k127_4375353_4 Erythromycin esterase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000006127 202.0
SHD3_k127_4375353_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000001979 166.0
SHD3_k127_4380755_0 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 288.0
SHD3_k127_4380755_1 - - - - 0.000000000000000000004512 99.0
SHD3_k127_4382036_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.256e-214 672.0
SHD3_k127_4382036_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 582.0
SHD3_k127_4382036_10 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000000000000000009281 175.0
SHD3_k127_4382036_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000006512 178.0
SHD3_k127_4382036_12 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000008471 162.0
SHD3_k127_4382036_13 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000005833 145.0
SHD3_k127_4382036_14 - K07112 - - 0.0000000000000000000000000000000000005111 145.0
SHD3_k127_4382036_15 TM2 domain - - - 0.0000000000000000000000000000000004388 135.0
SHD3_k127_4382036_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000001229 130.0
SHD3_k127_4382036_17 Ribosomal protein L36 K02919 - - 0.0000000000000009021 76.0
SHD3_k127_4382036_18 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000007431 61.0
SHD3_k127_4382036_2 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 486.0
SHD3_k127_4382036_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 362.0
SHD3_k127_4382036_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 327.0
SHD3_k127_4382036_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004264 281.0
SHD3_k127_4382036_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000684 214.0
SHD3_k127_4382036_7 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000002213 207.0
SHD3_k127_4382036_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002999 178.0
SHD3_k127_4382036_9 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000543 176.0
SHD3_k127_4401559_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 493.0
SHD3_k127_4401559_1 Tetratricopeptide repeat - - - 0.00000000000000000001369 95.0
SHD3_k127_4411388_0 synthase K15431,K16167,K16424,K19580 - 2.3.1.233,2.3.1.246,2.3.1.253 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 288.0
SHD3_k127_4411388_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000001568 75.0
SHD3_k127_4411388_2 Kazal type serine protease inhibitors - - - 0.00001949 49.0
SHD3_k127_4412497_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 468.0
SHD3_k127_4412497_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 308.0
SHD3_k127_4412497_2 PFAM TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008072 274.0
SHD3_k127_4412497_3 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000002758 246.0
SHD3_k127_4412497_4 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000004416 219.0
SHD3_k127_4412497_5 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000003836 203.0
SHD3_k127_4412497_6 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000004753 192.0
SHD3_k127_4412497_7 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000009358 149.0
SHD3_k127_4417687_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 515.0
SHD3_k127_4417687_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 492.0
SHD3_k127_4417687_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 331.0
SHD3_k127_4417687_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 299.0
SHD3_k127_4417687_4 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000008127 197.0
SHD3_k127_4417687_5 protein tyrosine phosphatase activity K01104,K19302 - 3.1.3.48,3.6.1.27 0.000000000000000000000000000000000000000000000000003906 189.0
SHD3_k127_4417687_6 glycogen (starch) synthase activity - - - 0.000000000000000000000000000000000000000000000000004375 196.0
SHD3_k127_4417687_7 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000155 173.0
SHD3_k127_4417687_8 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000007924 160.0
SHD3_k127_4417687_9 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000002892 103.0
SHD3_k127_4419118_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000001865 244.0
SHD3_k127_4419118_1 PFAM Carboxymuconolactone decarboxylase - - - 0.00009728 45.0
SHD3_k127_4419118_2 PFAM Carboxymuconolactone decarboxylase - - - 0.0006191 46.0
SHD3_k127_4423042_0 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 402.0
SHD3_k127_4423042_1 DNA-binding transcription factor activity K18996 - - 0.0000000000000000000000001922 109.0
SHD3_k127_4423986_0 FtsX-like permease family K02004 - - 1.087e-305 953.0
SHD3_k127_4423986_1 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 381.0
SHD3_k127_4425076_0 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 410.0
SHD3_k127_4425076_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000001967 121.0
SHD3_k127_4430_0 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 353.0
SHD3_k127_4430_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 350.0
SHD3_k127_4430_10 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000000000004273 186.0
SHD3_k127_4430_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000004503 171.0
SHD3_k127_4430_12 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000003812 147.0
SHD3_k127_4430_13 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000004449 149.0
SHD3_k127_4430_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 341.0
SHD3_k127_4430_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 327.0
SHD3_k127_4430_4 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 298.0
SHD3_k127_4430_5 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000003918 256.0
SHD3_k127_4430_6 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003101 250.0
SHD3_k127_4430_7 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000002001 235.0
SHD3_k127_4430_8 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000003966 230.0
SHD3_k127_4430_9 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000002717 200.0
SHD3_k127_4431672_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K21577 - 1.21.4.2,1.21.4.3,1.21.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 529.0
SHD3_k127_4431672_1 glycine betaine sarcosine D-proline reductase family K10672,K21579 - 1.21.4.2,1.21.4.4 0.0000000000000000000000000000000000362 135.0
SHD3_k127_4431672_2 Glycine reductase complex component B subunit gamma K10672 - 1.21.4.2 0.00000000000000000000000007792 107.0
SHD3_k127_4431672_3 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.00000000000000001279 87.0
SHD3_k127_4431672_4 In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000000000001253 81.0
SHD3_k127_4431672_5 Glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0001344 46.0
SHD3_k127_4440022_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 3.976e-243 764.0
SHD3_k127_4440022_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 9.725e-198 629.0
SHD3_k127_4440022_10 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000001258 145.0
SHD3_k127_4440022_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000008979 121.0
SHD3_k127_4440022_12 Protein of unknown function (DUF1573) - - - 0.0000000000003281 78.0
SHD3_k127_4440022_13 - - - - 0.0002677 44.0
SHD3_k127_4440022_2 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 562.0
SHD3_k127_4440022_3 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 572.0
SHD3_k127_4440022_4 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 499.0
SHD3_k127_4440022_5 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 481.0
SHD3_k127_4440022_6 Mo-molybdopterin cofactor metabolic process K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000001904 235.0
SHD3_k127_4440022_7 Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000114 227.0
SHD3_k127_4440022_8 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000000002644 179.0
SHD3_k127_4440022_9 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000025 171.0
SHD3_k127_4444201_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 433.0
SHD3_k127_4444201_1 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000491 236.0
SHD3_k127_4444201_2 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000000009698 216.0
SHD3_k127_4444201_3 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000004166 144.0
SHD3_k127_4446951_0 Histidine kinase K10715,K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 432.0
SHD3_k127_4446951_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000002341 221.0
SHD3_k127_4446951_2 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000001062 186.0
SHD3_k127_4446951_3 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000001795 175.0
SHD3_k127_4446951_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000003793 141.0
SHD3_k127_4446951_5 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000001485 86.0
SHD3_k127_4446951_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000001643 76.0
SHD3_k127_4447205_0 proline betaine transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 537.0
SHD3_k127_4447205_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 522.0
SHD3_k127_4447205_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 483.0
SHD3_k127_4447205_3 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000001263 190.0
SHD3_k127_4447205_4 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000008699 154.0
SHD3_k127_4447205_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000001378 114.0
SHD3_k127_4447205_6 EamA-like transporter family - - - 0.000000000000000000005608 104.0
SHD3_k127_4453899_0 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 444.0
SHD3_k127_4453899_1 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 364.0
SHD3_k127_4453899_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002058 233.0
SHD3_k127_4454739_0 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000001136 128.0
SHD3_k127_4454739_1 GAF domain K02482 - 2.7.13.3 0.000000000000000001965 99.0
SHD3_k127_4458495_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 417.0
SHD3_k127_4458495_1 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009931 283.0
SHD3_k127_4458495_2 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008366 234.0
SHD3_k127_4458495_3 denitrification pathway - - - 0.00000000000000000000000000004954 123.0
SHD3_k127_4458495_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000009855 57.0
SHD3_k127_4464160_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1024.0
SHD3_k127_4464160_1 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 467.0
SHD3_k127_4464160_10 electron transfer activity K05337,K17247 - - 0.000000000000641 69.0
SHD3_k127_4464160_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 418.0
SHD3_k127_4464160_3 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 368.0
SHD3_k127_4464160_4 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 290.0
SHD3_k127_4464160_5 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000004012 251.0
SHD3_k127_4464160_6 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000001159 190.0
SHD3_k127_4464160_8 Cysteine-rich small domain K07162 - - 0.000000000000000009357 86.0
SHD3_k127_4464160_9 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000003587 82.0
SHD3_k127_4468741_0 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000267 165.0
SHD3_k127_4483388_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 548.0
SHD3_k127_4483388_1 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 299.0
SHD3_k127_4483388_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001468 295.0
SHD3_k127_4483388_3 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002464 268.0
SHD3_k127_4483388_4 transposition - - - 0.0005067 45.0
SHD3_k127_4496185_0 Chromate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 485.0
SHD3_k127_4496185_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 385.0
SHD3_k127_4496185_2 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002119 265.0
SHD3_k127_4496185_3 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000003097 173.0
SHD3_k127_4502971_0 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000000000001274 130.0
SHD3_k127_4502971_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000001237 77.0
SHD3_k127_4502971_2 PFAM major facilitator superfamily MFS_1 - - - 0.00002387 48.0
SHD3_k127_45112_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 302.0
SHD3_k127_45112_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002328 276.0
SHD3_k127_45112_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000005429 244.0
SHD3_k127_45112_3 Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.000000000000000000000000000000000000000000000000001771 203.0
SHD3_k127_45112_4 response regulator, receiver - - - 0.00000000000000000000000000000292 138.0
SHD3_k127_45112_5 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000006174 118.0
SHD3_k127_4531467_0 DEAD DEAH box helicase K06877 - - 3.878e-213 686.0
SHD3_k127_4531467_1 type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 565.0
SHD3_k127_4531467_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000002574 153.0
SHD3_k127_4531467_11 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000001337 148.0
SHD3_k127_4531467_12 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000001122 140.0
SHD3_k127_4531467_13 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000001017 113.0
SHD3_k127_4531467_14 Fimbrial assembly protein (PilN) - - - 0.0000000001753 74.0
SHD3_k127_4531467_15 General secretion pathway protein K02457 - - 0.000000008829 64.0
SHD3_k127_4531467_16 fimbrial assembly K02461 - - 0.00000002016 67.0
SHD3_k127_4531467_17 Prokaryotic N-terminal methylation motif K02458 - - 0.000003021 54.0
SHD3_k127_4531467_18 Type II secretion system (T2SS), protein M subtype b - - - 0.000006199 56.0
SHD3_k127_4531467_19 Prokaryotic N-terminal methylation motif K02456,K02457,K02458,K02459,K02655,K10926 - - 0.0001581 52.0
SHD3_k127_4531467_2 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 397.0
SHD3_k127_4531467_20 - - - - 0.0005457 50.0
SHD3_k127_4531467_3 Glycosyl transferase, family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 321.0
SHD3_k127_4531467_4 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 330.0
SHD3_k127_4531467_5 Peptidylprolyl isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000009107 203.0
SHD3_k127_4531467_6 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000002536 179.0
SHD3_k127_4531467_7 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000001391 173.0
SHD3_k127_4531467_8 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000003472 168.0
SHD3_k127_4546461_0 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 321.0
SHD3_k127_4546461_1 Glycosyl transferase family 2 K12992 - - 0.00000000000000000000000000000000000000000000000007342 202.0
SHD3_k127_4546461_2 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000001524 175.0
SHD3_k127_4546461_3 Glycosyltransferase - - - 0.00000000000000000000000000000000000003477 165.0
SHD3_k127_4546461_4 Glycosyltransferase like family 2 K12992 - - 0.0000000000000000000000000000000000001523 152.0
SHD3_k127_4546461_5 PFAM Response regulator receiver domain K07658 - - 0.000000000009776 71.0
SHD3_k127_4548273_0 Domains REC, sigma54 interaction, HTH8 K02481 - - 4.015e-206 649.0
SHD3_k127_4548273_1 epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 570.0
SHD3_k127_4548273_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 524.0
SHD3_k127_4552424_0 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008326 298.0
SHD3_k127_4552424_1 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000001653 156.0
SHD3_k127_4558350_0 SMART Elongator protein 3 MiaB NifB - - - 7.021e-240 749.0
SHD3_k127_4560013_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 6.072e-229 716.0
SHD3_k127_4572478_0 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 417.0
SHD3_k127_4572478_1 Predicted membrane protein (DUF2127) - - - 0.000000000000000000000000000000000000000000000000007681 185.0
SHD3_k127_4572478_2 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000000001067 158.0
SHD3_k127_4572478_3 Belongs to the ompA family K03286 - - 0.00000000000000000000009977 108.0
SHD3_k127_4572478_4 acetyltransferase K00661 - 2.3.1.79 0.0000002059 61.0
SHD3_k127_4572478_5 Protein of unknown function DUF116 K09729 - - 0.00003236 53.0
SHD3_k127_4574708_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001504 274.0
SHD3_k127_4574708_1 Helix-turn-helix domain - - - 0.000000001611 63.0
SHD3_k127_4574708_2 Belongs to the peptidase S8 family - - - 0.0000006864 51.0
SHD3_k127_4577817_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 561.0
SHD3_k127_4577817_1 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 557.0
SHD3_k127_4577817_10 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000000002644 121.0
SHD3_k127_4577817_11 GDP-mannose mannosyl hydrolase activity - - - 0.00000000000000000002306 93.0
SHD3_k127_4577817_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 498.0
SHD3_k127_4577817_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 459.0
SHD3_k127_4577817_4 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 362.0
SHD3_k127_4577817_5 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 286.0
SHD3_k127_4577817_6 Two component regulator propeller K00936 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001487 246.0
SHD3_k127_4577817_7 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000003393 200.0
SHD3_k127_4577817_8 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000005504 160.0
SHD3_k127_4577817_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000001085 129.0
SHD3_k127_4580315_0 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 397.0
SHD3_k127_4580315_1 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000007774 215.0
SHD3_k127_4580315_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000004101 173.0
SHD3_k127_4580315_3 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000002771 121.0
SHD3_k127_4580315_4 FHA Domain - - - 0.0000000000000006559 81.0
SHD3_k127_4584137_0 Best Blastp hit gi 10176666 dbj BAB07760.1 (AP001520) BH4041 - - - 0.000000000000000000000000000000000000000000000248 183.0
SHD3_k127_4589696_0 2 iron, 2 sulfur cluster binding K07058 - - 0.0000000000000000000002405 100.0
SHD3_k127_4610940_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 451.0
SHD3_k127_4610940_1 PFAM Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 323.0
SHD3_k127_4610940_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 315.0
SHD3_k127_4610940_3 PFAM Glycosyl transferase family 2 K09931 - - 0.00000000000000000000000000000000000000000000000000001553 196.0
SHD3_k127_4610940_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931,K20742 - 3.4.14.13 0.00000000000000000000000000000000000000001461 163.0
SHD3_k127_4610940_5 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.0006926 49.0
SHD3_k127_4613624_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 443.0
SHD3_k127_4613624_1 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000001938 125.0
SHD3_k127_4613624_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000001055 57.0
SHD3_k127_4626435_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1066.0
SHD3_k127_4626435_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.227e-213 672.0
SHD3_k127_4626435_10 TraB family K09973 - - 0.0000000002297 66.0
SHD3_k127_4626435_2 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 6.323e-199 625.0
SHD3_k127_4626435_3 CoA binding domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 514.0
SHD3_k127_4626435_4 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 484.0
SHD3_k127_4626435_5 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 300.0
SHD3_k127_4626435_6 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003962 262.0
SHD3_k127_4626435_7 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000002306 243.0
SHD3_k127_4626435_8 radical SAM K06871 - - 0.0000000000000000000000000000000000000000001009 172.0
SHD3_k127_4649039_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 456.0
SHD3_k127_4649039_1 homolog of gamma-carboxymuconolactone decarboxylase subunit K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000007146 179.0
SHD3_k127_4649039_2 STAS domain K03321 - - 0.00000004781 54.0
SHD3_k127_4686806_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 302.0
SHD3_k127_4686806_1 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.00000000000000000000000000000000000000000000001476 176.0
SHD3_k127_4686806_2 nucleic-acid-binding protein contains PIN domain - - - 0.00000000000000000000000000000002614 130.0
SHD3_k127_4686806_3 SpoVT / AbrB like domain - - - 0.00000000000000000005697 91.0
SHD3_k127_4686806_4 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0001764 46.0
SHD3_k127_4706790_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 589.0
SHD3_k127_4706790_1 RND efflux system, outer membrane lipoprotein, NodT - - - 0.0000000000000000000009623 99.0
SHD3_k127_4725344_0 Flavin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 335.0
SHD3_k127_4725344_1 - - - - 0.0000000000000000000000002173 108.0
SHD3_k127_4755692_0 - - - - 0.00000000000000000000000000000000000000000000000000000002127 199.0
SHD3_k127_4755692_1 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000000000000000000001872 143.0
SHD3_k127_4755692_2 - - - - 0.0000000000000000001528 90.0
SHD3_k127_4755692_3 - - - - 0.0000000000000000006041 87.0
SHD3_k127_4755692_4 - - - - 0.000000000000000001257 87.0
SHD3_k127_4755692_6 - - - - 0.000000001233 61.0
SHD3_k127_4786780_0 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 319.0
SHD3_k127_4786780_1 Cache_2 - - - 0.00000000000000000000000001799 112.0
SHD3_k127_4814037_0 PFAM transposase IS4 family protein K07481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 498.0
SHD3_k127_4814037_1 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000009714 192.0
SHD3_k127_4814037_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000003315 180.0
SHD3_k127_4814037_3 Cupin 2, conserved barrel domain protein - - - 0.000004234 51.0
SHD3_k127_486938_0 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 369.0
SHD3_k127_490745_0 Cupin - - - 0.0000000000000000000000000000000000000001709 156.0
SHD3_k127_4940050_0 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 313.0
SHD3_k127_4940050_1 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000352 191.0
SHD3_k127_4940050_2 metalloendopeptidase activity K03799 - - 0.00000000000000000000000008566 119.0
SHD3_k127_494986_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 1.51e-310 973.0
SHD3_k127_494986_2 Peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.00000000000000000002251 103.0
SHD3_k127_494986_3 - - - - 0.00000005592 58.0
SHD3_k127_4969882_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 462.0
SHD3_k127_4969882_1 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000003549 151.0
SHD3_k127_4969882_2 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.000000003064 60.0
SHD3_k127_5009391_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 7.325e-258 801.0
SHD3_k127_5009391_1 cell redox homeostasis - - - 1.013e-209 665.0
SHD3_k127_5009391_10 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009535 249.0
SHD3_k127_5009391_11 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000004806 238.0
SHD3_k127_5009391_12 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000008623 221.0
SHD3_k127_5009391_13 response regulator - - - 0.0000000000000000000000000000000000009523 147.0
SHD3_k127_5009391_14 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000002024 140.0
SHD3_k127_5009391_15 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000000000006032 111.0
SHD3_k127_5009391_16 iron-sulfur cluster assembly - - - 0.000000000000000000000004936 102.0
SHD3_k127_5009391_17 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.00000000000000000000002516 100.0
SHD3_k127_5009391_18 TIGRFAM desulfoferrodoxin FeS4 iron-binding domain K05919 - 1.15.1.2 0.000000003542 58.0
SHD3_k127_5009391_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 600.0
SHD3_k127_5009391_20 PFAM Cobalt transport protein K16785 - - 0.00008145 53.0
SHD3_k127_5009391_3 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 477.0
SHD3_k127_5009391_4 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 437.0
SHD3_k127_5009391_5 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 371.0
SHD3_k127_5009391_6 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 334.0
SHD3_k127_5009391_7 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 327.0
SHD3_k127_5009391_8 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 290.0
SHD3_k127_5009391_9 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 258.0
SHD3_k127_5016229_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 496.0
SHD3_k127_5016229_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 479.0
SHD3_k127_5016229_2 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 387.0
SHD3_k127_5016229_3 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000000001798 126.0
SHD3_k127_5016229_4 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.0000000000000000004368 90.0
SHD3_k127_5016229_5 serine threonine protein kinase K12132 - 2.7.11.1 0.000000005679 68.0
SHD3_k127_5016229_6 - - - - 0.00000001156 60.0
SHD3_k127_5016229_7 Phage integrase, N-terminal SAM-like domain - - - 0.00002419 46.0
SHD3_k127_5017913_0 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 360.0
SHD3_k127_5017913_1 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003974 262.0
SHD3_k127_5022805_0 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 587.0
SHD3_k127_5022805_1 SNARE associated Golgi protein - - - 0.0000000000002435 72.0
SHD3_k127_5023714_0 ABC transporter K06158 - - 1.411e-242 764.0
SHD3_k127_5023714_1 PilZ domain - - - 0.0000000000000000000001675 106.0
SHD3_k127_5023714_2 O COG3187 Heat shock protein - - - 0.000000000003222 76.0
SHD3_k127_5023714_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000002114 52.0
SHD3_k127_502829_0 Cytochrome c554 and c-prime - - - 1.509e-231 725.0
SHD3_k127_502829_1 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000001593 209.0
SHD3_k127_5029239_0 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000003893 209.0
SHD3_k127_5044778_0 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000005403 136.0
SHD3_k127_5044778_1 Domain of unknown function (DUF1992) - - - 0.00001302 52.0
SHD3_k127_5044905_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 294.0
SHD3_k127_5044905_1 diguanylate cyclase - - - 0.00000000000000000000000000000000002644 153.0
SHD3_k127_5044905_2 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000001312 135.0
SHD3_k127_5044905_3 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000001028 98.0
SHD3_k127_5046329_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 1.507e-224 702.0
SHD3_k127_5046329_1 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 472.0
SHD3_k127_5046329_2 abc transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 320.0
SHD3_k127_5046329_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 330.0
SHD3_k127_5046329_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 326.0
SHD3_k127_5046329_5 macromolecule localization K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000000000001861 212.0
SHD3_k127_5046329_6 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000002024 116.0
SHD3_k127_5046329_7 peptidyl-tyrosine sulfation - - - 0.0003878 50.0
SHD3_k127_5057020_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 545.0
SHD3_k127_5057020_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 365.0
SHD3_k127_5057020_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 337.0
SHD3_k127_5057020_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000002171 168.0
SHD3_k127_5057020_4 oligosaccharyl transferase activity - - - 0.0000000036 62.0
SHD3_k127_5057020_5 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.00001293 55.0
SHD3_k127_5059351_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.02e-260 814.0
SHD3_k127_5059351_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 476.0
SHD3_k127_5059351_10 Signal transduction response regulator, receiver domain - - - 0.00000000000000000000000000000000000000000000000000008649 195.0
SHD3_k127_5059351_11 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000001073 168.0
SHD3_k127_5059351_12 Two component regulator propeller - - - 0.000000000000000000000396 106.0
SHD3_k127_5059351_14 radical SAM domain protein - - - 0.0000000000000000003146 91.0
SHD3_k127_5059351_15 Sigma-54 interaction domain - - - 0.00001207 49.0
SHD3_k127_5059351_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 454.0
SHD3_k127_5059351_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 426.0
SHD3_k127_5059351_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 416.0
SHD3_k127_5059351_5 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 290.0
SHD3_k127_5059351_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000001088 234.0
SHD3_k127_5059351_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000008403 209.0
SHD3_k127_5059351_8 O-methyltransferase family 3 - - - 0.0000000000000000000000000000000000000000000000000000000001699 211.0
SHD3_k127_5059351_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006718 205.0
SHD3_k127_5067613_0 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.0000002157 54.0
SHD3_k127_5067613_1 peptidylprolyl isomerase K03770 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 0.0000148 57.0
SHD3_k127_5067613_2 Tetratricopeptide repeat - - - 0.0002485 53.0
SHD3_k127_5079081_0 PFAM Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001684 254.0
SHD3_k127_5079081_1 Integrase core domain K07497 - - 0.0003809 48.0
SHD3_k127_5098247_0 Virulence factor BrkB K07058 - - 0.00000000000000000000000001379 120.0
SHD3_k127_5098247_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000001517 79.0
SHD3_k127_5098247_2 AI-2E family transporter - - - 0.0000000000003319 74.0
SHD3_k127_5098247_3 arginine decarboxylase activity K02626 - 4.1.1.19 0.00000001305 59.0
SHD3_k127_5100326_0 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000008496 154.0
SHD3_k127_5100326_1 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000578 145.0
SHD3_k127_5100326_2 - - - - 0.000000000000000000000000005582 110.0
SHD3_k127_5100593_0 Seven times multi-haem cytochrome CxxCH - - - 4.688e-196 617.0
SHD3_k127_5100593_1 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 613.0
SHD3_k127_5100593_2 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001485 245.0
SHD3_k127_5100593_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006715 226.0
SHD3_k127_5100593_4 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000001465 216.0
SHD3_k127_5100593_5 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000002599 152.0
SHD3_k127_5100593_6 PFAM UspA domain protein K06149 - - 0.0000000104 62.0
SHD3_k127_5101147_0 filamentation induced by cAMP protein Fic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 530.0
SHD3_k127_5101147_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000005047 145.0
SHD3_k127_5101147_2 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000002831 110.0
SHD3_k127_5104010_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 342.0
SHD3_k127_5104010_1 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000000000000000000001242 227.0
SHD3_k127_5104010_2 sulfuric ester hydrolase activity K03760,K19353 - 2.7.8.43 0.0000000000000000000000000000000000000001619 171.0
SHD3_k127_5104010_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000003283 78.0
SHD3_k127_5136011_0 - - - - 0.000000000000000000000000000000000000000000000004068 177.0
SHD3_k127_5136011_1 MarC family integral membrane protein - - - 0.00000000000000000000000000000000000000000002417 168.0
SHD3_k127_5136011_2 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000005608 150.0
SHD3_k127_5136011_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000001691 145.0
SHD3_k127_5136011_4 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000001327 119.0
SHD3_k127_5136011_6 - - - - 0.0000000000001 74.0
SHD3_k127_5138022_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 586.0
SHD3_k127_5141203_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 458.0
SHD3_k127_5141203_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001492 256.0
SHD3_k127_5141203_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002121 250.0
SHD3_k127_5141203_3 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000008191 213.0
SHD3_k127_5141203_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000002459 207.0
SHD3_k127_5141203_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000004789 199.0
SHD3_k127_5141203_6 YGGT family K02221 - - 0.00000000000000000000000000000003085 129.0
SHD3_k127_5141203_7 cheY-homologous receiver domain - - - 0.000000000000000000000000000001013 125.0
SHD3_k127_5141203_8 LysE type translocator - - - 0.000000000000000000000000000001574 123.0
SHD3_k127_5141203_9 Belongs to the UPF0324 family - - - 0.000000000001981 78.0
SHD3_k127_5149785_0 Transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000001891 173.0
SHD3_k127_5153225_0 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 543.0
SHD3_k127_5153225_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 522.0
SHD3_k127_5153225_2 HEAT-like repeat - - - 0.00000000000000000000004247 108.0
SHD3_k127_5153225_3 lyase activity - - - 0.000000000000000001437 89.0
SHD3_k127_5153225_4 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.0000000000001138 72.0
SHD3_k127_5161949_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 388.0
SHD3_k127_5161949_1 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000139 258.0
SHD3_k127_5161949_2 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000000000005033 227.0
SHD3_k127_5161949_3 biopolymer transport protein - - - 0.000000000000000000000000000000000000000000000000000001766 196.0
SHD3_k127_5161949_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K07114 - - 0.0000108 56.0
SHD3_k127_5162257_0 GAF domain - - - 2.295e-202 681.0
SHD3_k127_5162257_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 535.0
SHD3_k127_5162257_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 427.0
SHD3_k127_5162257_3 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 329.0
SHD3_k127_5162257_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 316.0
SHD3_k127_5162257_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000009985 251.0
SHD3_k127_5162257_6 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000001516 170.0
SHD3_k127_5162257_7 radical SAM domain protein - - - 0.00000000000000000000000000000000997 139.0
SHD3_k127_5162257_8 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000001355 108.0
SHD3_k127_5162257_9 Belongs to the peptidase S8 family - - - 0.00000000000009989 81.0
SHD3_k127_5164164_0 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000002903 170.0
SHD3_k127_5164164_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000005188 111.0
SHD3_k127_5169935_0 LTXXQ motif family protein - - - 0.000000000000000000000000000000000008335 141.0
SHD3_k127_5170372_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1794.0
SHD3_k127_5170372_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 556.0
SHD3_k127_5170372_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 527.0
SHD3_k127_5188087_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 2.748e-290 902.0
SHD3_k127_5188087_1 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 460.0
SHD3_k127_5188087_10 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000004806 228.0
SHD3_k127_5188087_11 PFAM Pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000002306 164.0
SHD3_k127_5188087_12 Hydrogenase (NiFe) small subunit HydA K05927,K06282,K18008 - 1.12.2.1,1.12.5.1,1.12.99.6 0.000000000000000000000000000000000005314 139.0
SHD3_k127_5188087_13 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000001268 134.0
SHD3_k127_5188087_14 Protein of unknown function (DUF1189) - - - 0.000000000000000000001933 104.0
SHD3_k127_5188087_15 Cytochrome c3 - - - 0.00000000000827 66.0
SHD3_k127_5188087_16 PFAM cytochrome c class I - - - 0.0000000003455 64.0
SHD3_k127_5188087_17 Response regulator receiver domain K03413 - - 0.000000007755 65.0
SHD3_k127_5188087_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 377.0
SHD3_k127_5188087_3 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 303.0
SHD3_k127_5188087_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 303.0
SHD3_k127_5188087_5 Histidine kinase K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001843 284.0
SHD3_k127_5188087_6 Oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005093 269.0
SHD3_k127_5188087_7 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000226 247.0
SHD3_k127_5188087_8 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000009132 233.0
SHD3_k127_5188087_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006508 232.0
SHD3_k127_5188879_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.559e-267 835.0
SHD3_k127_5188879_1 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 4.019e-241 763.0
SHD3_k127_5188879_10 YdjC-like protein - - - 0.0000000000000000000000000000000000000000000000000203 191.0
SHD3_k127_5188879_11 viral genome integration into host DNA K04763 - - 0.0000000000000000000000000000000000000000000002786 174.0
SHD3_k127_5188879_12 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000001375 143.0
SHD3_k127_5188879_13 MlaC protein K07323 - - 0.0000000000000000000000000000000002862 139.0
SHD3_k127_5188879_14 viral genome integration into host DNA K04763 - - 0.0000000000000000000000005224 105.0
SHD3_k127_5188879_15 PFAM RNA recognition motif - - - 0.000000000000000000000003781 106.0
SHD3_k127_5188879_16 EamA-like transporter family - - - 0.0000000000000000002211 94.0
SHD3_k127_5188879_17 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000006062 78.0
SHD3_k127_5188879_18 Carotenoid biosynthesis protein - - - 0.000000000000001207 79.0
SHD3_k127_5188879_2 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 568.0
SHD3_k127_5188879_3 TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 561.0
SHD3_k127_5188879_4 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 409.0
SHD3_k127_5188879_5 Domain of unknown function (DUF3463) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 394.0
SHD3_k127_5188879_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 376.0
SHD3_k127_5188879_7 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004033 271.0
SHD3_k127_5188879_8 - - - - 0.000000000000000000000000000000000000000000000000000000000001714 221.0
SHD3_k127_5188879_9 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000002189 192.0
SHD3_k127_5204526_0 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000001108 198.0
SHD3_k127_5204526_1 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000001896 153.0
SHD3_k127_5204526_2 energy transducer activity K03646,K03832 - - 0.0000000000001741 79.0
SHD3_k127_5204526_3 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000001656 63.0
SHD3_k127_5208314_0 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000000000000000004049 143.0
SHD3_k127_5208314_2 PFAM SNARE associated Golgi protein - - - 0.000000000007452 65.0
SHD3_k127_5208314_3 SNARE associated Golgi protein - - - 0.000003884 52.0
SHD3_k127_5212742_0 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000001224 176.0
SHD3_k127_5212742_1 part of a sulfur-relay system K11179 - - 0.000000000000000000000000001173 113.0
SHD3_k127_5232031_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 391.0
SHD3_k127_5232031_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 376.0
SHD3_k127_5243516_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 9.641e-283 880.0
SHD3_k127_5243516_1 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 485.0
SHD3_k127_5243516_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000716 183.0
SHD3_k127_5243516_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000006381 86.0
SHD3_k127_5266069_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004869 258.0
SHD3_k127_5266069_1 response regulator, receiver - - - 0.000004765 50.0
SHD3_k127_5267816_0 O-methyltransferase activity - - - 8.111e-209 668.0
SHD3_k127_5267816_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 1.103e-204 646.0
SHD3_k127_5267816_10 LysM domain - - - 0.0000000000000000000000000000000000001069 154.0
SHD3_k127_5267816_11 PFAM Protein-tyrosine phosphatase, low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000000000000891 115.0
SHD3_k127_5267816_12 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.00000000000000000000000002869 115.0
SHD3_k127_5267816_2 Thiamine pyrophosphate enzyme, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 579.0
SHD3_k127_5267816_3 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 428.0
SHD3_k127_5267816_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 438.0
SHD3_k127_5267816_5 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004715 259.0
SHD3_k127_5267816_6 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000002291 209.0
SHD3_k127_5267816_7 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000001052 204.0
SHD3_k127_5267816_8 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000005806 197.0
SHD3_k127_5267816_9 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000004961 154.0
SHD3_k127_5279084_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 531.0
SHD3_k127_5279084_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009762 525.0
SHD3_k127_5279084_2 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 497.0
SHD3_k127_5279084_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 357.0
SHD3_k127_5279084_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 327.0
SHD3_k127_5279084_5 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000002662 196.0
SHD3_k127_5286760_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000007594 121.0
SHD3_k127_5286760_1 Cytochrome c K00413 - - 0.000000000000000000000006651 108.0
SHD3_k127_5289824_0 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 1.215e-277 872.0
SHD3_k127_5289824_1 - - - - 6.11e-232 738.0
SHD3_k127_5289824_10 Outer membrane efflux protein - - - 0.00000000001265 78.0
SHD3_k127_5289824_11 GMC oxidoreductase K03333 - 1.1.3.6 0.0000000000168 69.0
SHD3_k127_5289824_2 Belongs to the peptidase S8 family - - - 2.291e-201 642.0
SHD3_k127_5289824_3 PFAM UBA THIF-type NAD FAD binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 376.0
SHD3_k127_5289824_4 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 304.0
SHD3_k127_5289824_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000003395 208.0
SHD3_k127_5289824_6 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000002238 201.0
SHD3_k127_5289824_8 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.000000000000000000000464 108.0
SHD3_k127_5289824_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000001826 93.0
SHD3_k127_5295959_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 7.399e-223 699.0
SHD3_k127_5295959_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 7.251e-200 632.0
SHD3_k127_5295959_10 YtxH-like protein - - - 0.0000000000000000000000001584 109.0
SHD3_k127_5295959_11 SMART Rhodanese domain protein - - - 0.0000000000000000000000005871 106.0
SHD3_k127_5295959_12 peptidyl-tyrosine sulfation - - - 0.00000000004993 72.0
SHD3_k127_5295959_14 - - - - 0.0000743 53.0
SHD3_k127_5295959_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 434.0
SHD3_k127_5295959_3 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 418.0
SHD3_k127_5295959_4 S-methyl-5-thioadenosine phosphorylase activity K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004645,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010033,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017061,GO:0017144,GO:0019221,GO:0019509,GO:0019752,GO:0023052,GO:0032259,GO:0034097,GO:0034641,GO:0035722,GO:0042221,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070671,GO:0070887,GO:0071265,GO:0071267,GO:0071310,GO:0071345,GO:0071349,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 330.0
SHD3_k127_5295959_5 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 317.0
SHD3_k127_5295959_6 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 303.0
SHD3_k127_5295959_7 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000004001 193.0
SHD3_k127_5295959_8 nickel cation binding K04651,K19640 - - 0.00000000000000000000000000000006919 128.0
SHD3_k127_5295959_9 Stringent starvation protein B K09985 - - 0.000000000000000000000000000008087 123.0
SHD3_k127_5301779_0 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000002689 219.0
SHD3_k127_5301779_1 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000008766 63.0
SHD3_k127_5307456_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 318.0
SHD3_k127_5307456_1 Exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000006915 162.0
SHD3_k127_5315168_0 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 404.0
SHD3_k127_5315168_1 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 344.0
SHD3_k127_5315168_2 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008256 246.0
SHD3_k127_5315168_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000006124 236.0
SHD3_k127_5315168_4 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000000000000000000597 221.0
SHD3_k127_5315168_5 HD domain K06950 - - 0.0000000000000000000000000000000000000000000000000001874 192.0
SHD3_k127_5315168_6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000001719 183.0
SHD3_k127_5315168_7 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 0.00000000000000001685 82.0
SHD3_k127_5315868_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000006875 228.0
SHD3_k127_5315868_1 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000002649 115.0
SHD3_k127_5315868_2 polysaccharide deacetylase K01181,K22278 - 3.2.1.8,3.5.1.104 0.00002815 49.0
SHD3_k127_5335655_0 Exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000002855 181.0
SHD3_k127_5335655_1 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000002362 126.0
SHD3_k127_5335655_2 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000001114 89.0
SHD3_k127_5352298_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 563.0
SHD3_k127_5352298_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 449.0
SHD3_k127_5352298_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000008175 141.0
SHD3_k127_5352298_3 Bacterial membrane protein YfhO - - - 0.00004392 51.0
SHD3_k127_5353993_0 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 568.0
SHD3_k127_5353993_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 394.0
SHD3_k127_5353993_2 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005439 284.0
SHD3_k127_5353993_3 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004719 242.0
SHD3_k127_5353993_4 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000004383 225.0
SHD3_k127_5353993_5 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000004446 122.0
SHD3_k127_5353993_6 - - - - 0.0000002439 53.0
SHD3_k127_5354676_0 Sigma-54 interaction domain K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 509.0
SHD3_k127_5354676_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 473.0
SHD3_k127_5354676_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 434.0
SHD3_k127_5354676_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 376.0
SHD3_k127_5354676_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 290.0
SHD3_k127_5354676_5 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000006315 220.0
SHD3_k127_5354676_6 Protein of unknown function (DUF3309) - - - 0.0000000000000000002654 89.0
SHD3_k127_5354676_7 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000007929 75.0
SHD3_k127_5361280_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 8.788e-263 816.0
SHD3_k127_5361280_1 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000003583 238.0
SHD3_k127_5361280_2 PHP-associated K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000006288 198.0
SHD3_k127_5361280_3 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000008521 180.0
SHD3_k127_5361280_4 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000008064 181.0
SHD3_k127_5361280_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000002802 134.0
SHD3_k127_5375792_0 Domain of unknown function (DUF4070) - - - 1.34e-208 659.0
SHD3_k127_5375792_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000003294 175.0
SHD3_k127_5401218_0 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000000000000000005017 169.0
SHD3_k127_5401218_1 transposase activity - - - 0.0000000000000000000000000000000002766 142.0
SHD3_k127_5401218_2 transposase activity - - - 0.00000000000000000002014 98.0
SHD3_k127_5414897_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 354.0
SHD3_k127_5492555_0 Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 375.0
SHD3_k127_5492555_1 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000001873 130.0
SHD3_k127_5492555_2 PFAM Glycoside hydrolase 15-related - - - 0.0000000001375 63.0
SHD3_k127_5494187_0 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000005583 115.0
SHD3_k127_5499428_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.858e-266 837.0
SHD3_k127_5499428_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 491.0
SHD3_k127_5499428_10 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000001202 117.0
SHD3_k127_5499428_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000115 115.0
SHD3_k127_5499428_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000001714 104.0
SHD3_k127_5499428_13 Protein of unknown function (DUF507) - - - 0.000000000000000000000003263 104.0
SHD3_k127_5499428_14 4Fe-4S binding domain - - - 0.000000000000000009756 84.0
SHD3_k127_5499428_2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 468.0
SHD3_k127_5499428_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 355.0
SHD3_k127_5499428_4 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005492 249.0
SHD3_k127_5499428_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000007086 225.0
SHD3_k127_5499428_6 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000001259 198.0
SHD3_k127_5499428_7 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000005136 160.0
SHD3_k127_5499428_8 SMART HNH nuclease K07451 - - 0.000000000000000000000000000000000000007059 150.0
SHD3_k127_5499428_9 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000000000000000000000000000004855 141.0
SHD3_k127_5517143_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 382.0
SHD3_k127_5517143_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 354.0
SHD3_k127_5517143_3 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 337.0
SHD3_k127_5517143_4 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 294.0
SHD3_k127_5517143_5 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000003892 236.0
SHD3_k127_5517143_6 - - - - 0.0000000000000000000000000002157 122.0
SHD3_k127_5517143_7 Predicted membrane protein (DUF2318) - - - 0.000000000000000000000000921 111.0
SHD3_k127_5535783_0 cell wall hydrolase K01449 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000001038 259.0
SHD3_k127_5535783_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000006346 219.0
SHD3_k127_5556741_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 578.0
SHD3_k127_5556741_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004134 268.0
SHD3_k127_5556741_2 Chalcone and stilbene synthases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000008046 212.0
SHD3_k127_5556741_3 - - - - 0.000000000000000000000000000000000000000000000000000005719 209.0
SHD3_k127_5556741_4 - - - - 0.000000000000000000000000000000000000005054 151.0
SHD3_k127_5556741_6 Cytochrome c - - - 0.0000000000000000002246 102.0
SHD3_k127_5556741_7 PFAM Cytochrome C - - - 0.0001221 50.0
SHD3_k127_558412_0 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 437.0
SHD3_k127_558412_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 337.0
SHD3_k127_558412_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000003499 220.0
SHD3_k127_576719_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 484.0
SHD3_k127_576719_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 353.0
SHD3_k127_576719_2 peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000003217 147.0
SHD3_k127_576719_3 Tetratricopeptide repeat - - - 0.000000000000000005125 93.0
SHD3_k127_59809_0 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 471.0
SHD3_k127_59809_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007436 281.0
SHD3_k127_59809_2 CytoplasmicMembrane, score 9.99 - - - 0.000000000000000000000000000000007272 147.0
SHD3_k127_59809_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000001096 117.0
SHD3_k127_59809_4 - - - - 0.0000000003788 63.0
SHD3_k127_610574_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1153.0
SHD3_k127_610574_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1024.0
SHD3_k127_610574_10 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000133 285.0
SHD3_k127_610574_11 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003811 288.0
SHD3_k127_610574_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005612 271.0
SHD3_k127_610574_13 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000001626 246.0
SHD3_k127_610574_14 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000323 256.0
SHD3_k127_610574_15 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000002066 250.0
SHD3_k127_610574_16 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000015 231.0
SHD3_k127_610574_17 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000001803 229.0
SHD3_k127_610574_18 Pfam:TPM K08988 - - 0.000000000000000000000000000000000000000000000000000000000001732 222.0
SHD3_k127_610574_19 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000002973 209.0
SHD3_k127_610574_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 593.0
SHD3_k127_610574_20 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000166 187.0
SHD3_k127_610574_21 Protein of unknown function (DUF2844) - - - 0.00000000000000000000000000000000000000000001043 167.0
SHD3_k127_610574_22 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000003713 168.0
SHD3_k127_610574_23 Dihydroneopterin aldolase - - - 0.00000000000000000000000000000000000000388 154.0
SHD3_k127_610574_24 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000001313 149.0
SHD3_k127_610574_25 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000002308 151.0
SHD3_k127_610574_26 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000001204 141.0
SHD3_k127_610574_27 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000002577 126.0
SHD3_k127_610574_28 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.000000000000000000000000000004595 127.0
SHD3_k127_610574_29 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000008173 123.0
SHD3_k127_610574_3 spermidine synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 510.0
SHD3_k127_610574_30 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592 - 0.000000000000000000000001011 104.0
SHD3_k127_610574_31 PFAM Cold-shock protein DNA-binding K03704 - - 0.000000000000000000000005153 104.0
SHD3_k127_610574_32 acr, cog1993 K09137 - - 0.0000000000000000000003416 99.0
SHD3_k127_610574_33 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000006605 99.0
SHD3_k127_610574_34 NusG domain II K00805 - 2.5.1.30 0.000000000000000002261 89.0
SHD3_k127_610574_35 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000001188 83.0
SHD3_k127_610574_36 Cytochrome c K12263 - - 0.0000000000000002659 85.0
SHD3_k127_610574_37 - - - - 0.0000000000003655 72.0
SHD3_k127_610574_38 Protein of unknown function (DUF1573) - - - 0.00003002 48.0
SHD3_k127_610574_4 Protein of unknown function (DUF3443) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 417.0
SHD3_k127_610574_5 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 380.0
SHD3_k127_610574_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 362.0
SHD3_k127_610574_7 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 346.0
SHD3_k127_610574_8 CO dehydrogenase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 304.0
SHD3_k127_610574_9 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 292.0
SHD3_k127_65089_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 419.0
SHD3_k127_65089_1 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000008483 166.0
SHD3_k127_65089_2 PFAM DSBA oxidoreductase - - - 0.0003365 45.0
SHD3_k127_659687_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 498.0
SHD3_k127_659687_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases - - - 0.0000000000000002646 80.0
SHD3_k127_661185_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.048e-222 699.0
SHD3_k127_661185_1 cobalt ion transport K02007,K02009,K16915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 399.0
SHD3_k127_661185_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 325.0
SHD3_k127_661185_3 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003324 275.0
SHD3_k127_661185_4 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000006302 183.0
SHD3_k127_661185_5 MgtC family K07507 - - 0.0000000000000000000000000000000001116 140.0
SHD3_k127_661185_6 aminopeptidase activity - - - 0.000000000000000004077 89.0
SHD3_k127_67249_0 Archaeal transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000001741 167.0
SHD3_k127_67249_1 - - - - 0.0000005263 51.0
SHD3_k127_700995_0 PFAM Integrase K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 306.0
SHD3_k127_700995_1 transposase activity K07483 - - 0.0000000000000000000445 93.0
SHD3_k127_706223_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 395.0
SHD3_k127_706223_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 317.0
SHD3_k127_706223_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000004882 242.0
SHD3_k127_706223_3 heme binding K06386,K19304,K21471 - - 0.00000000000000000000000000000000000000000001536 172.0
SHD3_k127_706223_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.000000000000000000000000000007282 132.0
SHD3_k127_706223_5 MMPL family K03296 - - 0.00000000000000000002786 91.0
SHD3_k127_718584_0 Transposase - - - 0.00000000000000000000000000000001903 131.0
SHD3_k127_718584_1 DDE superfamily endonuclease - - - 0.00000000000000000000000000001412 124.0
SHD3_k127_71867_0 SWI complex, BAF60b domains - - - 0.00000000000000000000000000002471 119.0
SHD3_k127_71867_1 PFAM Endoribonuclease L-PSP - - - 0.00000000000001348 74.0
SHD3_k127_718678_0 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 291.0
SHD3_k127_718678_1 recombinase XerD K04763 - - 0.000000000000000000000000002866 118.0
SHD3_k127_718678_2 curli production assembly transport component CsgG - - - 0.0000000000000000000000001132 110.0
SHD3_k127_721461_0 PFAM magnesium chelatase ChlI subunit K07391 - - 1.588e-205 651.0
SHD3_k127_721461_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 316.0
SHD3_k127_721461_3 Regulatory protein, FmdB family - - - 0.000000000000000002533 86.0
SHD3_k127_723742_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.023e-285 891.0
SHD3_k127_723742_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.847e-227 715.0
SHD3_k127_723742_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003147 252.0
SHD3_k127_723742_11 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000001642 215.0
SHD3_k127_723742_12 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000005622 202.0
SHD3_k127_723742_13 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000000000000007188 203.0
SHD3_k127_723742_14 arabinan catabolic process K06113 - 3.2.1.99 0.00000000000000000000000000000000000000000001159 175.0
SHD3_k127_723742_15 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000001067 162.0
SHD3_k127_723742_16 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000004805 158.0
SHD3_k127_723742_17 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000002694 132.0
SHD3_k127_723742_18 DNA-damage-inducible protein d K14623 - - 0.000000000000000000000002859 104.0
SHD3_k127_723742_19 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000001665 98.0
SHD3_k127_723742_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 559.0
SHD3_k127_723742_20 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.0000000000000000001185 93.0
SHD3_k127_723742_21 - - - - 0.0000001389 53.0
SHD3_k127_723742_22 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000001389 53.0
SHD3_k127_723742_23 Evidence 5 No homology to any previously reported sequences - - - 0.00000152 50.0
SHD3_k127_723742_24 Zn-ribbon protein possibly nucleic acid-binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00006791 54.0
SHD3_k127_723742_25 Tetratricopeptide repeat protein - - - 0.0002943 51.0
SHD3_k127_723742_3 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 542.0
SHD3_k127_723742_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 527.0
SHD3_k127_723742_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 524.0
SHD3_k127_723742_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 481.0
SHD3_k127_723742_7 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 366.0
SHD3_k127_723742_8 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 332.0
SHD3_k127_723742_9 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006648 271.0
SHD3_k127_741976_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1064.0
SHD3_k127_741976_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 5.455e-251 782.0
SHD3_k127_741976_10 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 455.0
SHD3_k127_741976_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 464.0
SHD3_k127_741976_12 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 447.0
SHD3_k127_741976_13 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 446.0
SHD3_k127_741976_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 381.0
SHD3_k127_741976_15 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 363.0
SHD3_k127_741976_16 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 365.0
SHD3_k127_741976_17 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 340.0
SHD3_k127_741976_18 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 309.0
SHD3_k127_741976_19 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 306.0
SHD3_k127_741976_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 7.728e-219 688.0
SHD3_k127_741976_20 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 328.0
SHD3_k127_741976_21 Pfam:Arch_ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 288.0
SHD3_k127_741976_22 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 286.0
SHD3_k127_741976_23 ATPases associated with a variety of cellular activities K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001249 287.0
SHD3_k127_741976_24 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004255 273.0
SHD3_k127_741976_25 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000003265 270.0
SHD3_k127_741976_26 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005052 276.0
SHD3_k127_741976_27 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007983 273.0
SHD3_k127_741976_28 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000001487 221.0
SHD3_k127_741976_29 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000002125 204.0
SHD3_k127_741976_3 Sigma54 specific transcriptional regulator, Fis family - - - 1.207e-209 666.0
SHD3_k127_741976_30 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000007211 184.0
SHD3_k127_741976_31 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000007569 186.0
SHD3_k127_741976_32 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000000009215 165.0
SHD3_k127_741976_33 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000003253 149.0
SHD3_k127_741976_34 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000000000006759 159.0
SHD3_k127_741976_35 OstA-like protein K09774 - - 0.0000000000000000000000000000000000002615 145.0
SHD3_k127_741976_36 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000375 136.0
SHD3_k127_741976_37 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000007414 128.0
SHD3_k127_741976_38 thiolester hydrolase activity - - - 0.00000000000000000000000000003485 123.0
SHD3_k127_741976_39 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000001333 120.0
SHD3_k127_741976_4 also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity K01659 - 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 572.0
SHD3_k127_741976_40 Protein of unknown function (DUF3187) - - - 0.00000000000000000000000704 111.0
SHD3_k127_741976_41 PFAM CheW domain protein K03408 - - 0.000000000000000000001859 103.0
SHD3_k127_741976_42 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.000000000000000009535 85.0
SHD3_k127_741976_43 - - - - 0.00000000001071 73.0
SHD3_k127_741976_44 PASTA K12132 - 2.7.11.1 0.00000000009781 71.0
SHD3_k127_741976_45 transferase activity, transferring glycosyl groups - - - 0.000000001134 65.0
SHD3_k127_741976_46 competence protein - - - 0.0000000713 64.0
SHD3_k127_741976_47 - - - - 0.000003728 54.0
SHD3_k127_741976_49 Lipopolysaccharide-assembly, LptC-related - - - 0.0000917 51.0
SHD3_k127_741976_5 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 561.0
SHD3_k127_741976_50 type IV pilus secretin PilQ K02666 - - 0.0003204 50.0
SHD3_k127_741976_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 548.0
SHD3_k127_741976_7 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 517.0
SHD3_k127_741976_8 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 523.0
SHD3_k127_741976_9 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 491.0
SHD3_k127_750870_0 ATPases associated with a variety of cellular activities K01990,K11050 - - 0.0000000000000000004198 89.0
SHD3_k127_752940_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1523.0
SHD3_k127_752940_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 505.0
SHD3_k127_752940_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 498.0
SHD3_k127_752940_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 389.0
SHD3_k127_752940_4 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 299.0
SHD3_k127_752940_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000009754 237.0
SHD3_k127_752940_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000005279 216.0
SHD3_k127_761102_0 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 438.0
SHD3_k127_761102_1 transposase activity K07483,K07497 - - 0.00000000000000001425 86.0
SHD3_k127_766314_0 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 515.0
SHD3_k127_766314_1 PFAM transglutaminase domain protein - - - 0.0000000006399 61.0
SHD3_k127_775646_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1105.0
SHD3_k127_777506_0 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 460.0
SHD3_k127_777506_1 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 434.0
SHD3_k127_777506_2 Histidine kinase A domain protein - - - 0.000000000000000000002405 101.0
SHD3_k127_777506_3 Domain of Unknown Function (DUF748) - - - 0.00000002525 55.0
SHD3_k127_783314_0 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 396.0
SHD3_k127_783314_1 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001972 273.0
SHD3_k127_783314_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000002275 95.0
SHD3_k127_795472_0 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000005563 135.0
SHD3_k127_796406_0 Belongs to the peptidase M48B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001226 244.0
SHD3_k127_804453_0 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000003474 218.0
SHD3_k127_804453_1 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000001141 121.0
SHD3_k127_804453_2 - - - - 0.0005155 46.0
SHD3_k127_81307_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 432.0
SHD3_k127_81307_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0001088 45.0
SHD3_k127_823062_0 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000003924 225.0
SHD3_k127_823062_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000076 224.0
SHD3_k127_823062_2 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000008167 210.0
SHD3_k127_823062_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000006837 143.0
SHD3_k127_823062_4 ABC transporter K02065 - - 0.00006711 46.0
SHD3_k127_829426_0 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 455.0
SHD3_k127_829426_1 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 333.0
SHD3_k127_829426_2 Pentapeptide repeats (9 copies) - - - 0.0000006857 53.0
SHD3_k127_82955_0 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000003812 191.0
SHD3_k127_82955_1 - - - - 0.00000000000000000005051 93.0
SHD3_k127_829802_0 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000001733 108.0
SHD3_k127_829802_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000007002 100.0
SHD3_k127_832573_0 Belongs to the peptidase M16 family K07263 - - 0.0 1019.0
SHD3_k127_832573_1 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 1.155e-290 914.0
SHD3_k127_832573_10 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 319.0
SHD3_k127_832573_11 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001531 266.0
SHD3_k127_832573_12 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000003323 226.0
SHD3_k127_832573_13 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000002543 224.0
SHD3_k127_832573_14 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000007673 222.0
SHD3_k127_832573_15 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000007569 186.0
SHD3_k127_832573_16 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000704 158.0
SHD3_k127_832573_17 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000008141 134.0
SHD3_k127_832573_18 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000000000077 120.0
SHD3_k127_832573_19 Domain of unknown function (DUF4203) - - - 0.0000000000000000000000000002222 120.0
SHD3_k127_832573_2 UvrD-like helicase C-terminal domain K03656,K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 609.0
SHD3_k127_832573_20 - - - - 0.0000000000000000000000001181 111.0
SHD3_k127_832573_21 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000003409 98.0
SHD3_k127_832573_22 domain protein - - - 0.000000000000000002288 100.0
SHD3_k127_832573_23 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000732 81.0
SHD3_k127_832573_24 - - - - 0.00000000008027 65.0
SHD3_k127_832573_25 - K07092 - - 0.00008467 50.0
SHD3_k127_832573_26 - K07272,K20543,K21007 - - 0.0002622 49.0
SHD3_k127_832573_27 Fe-S-cluster oxidoreductase K06940 - - 0.0003166 44.0
SHD3_k127_832573_28 - - - - 0.0008663 52.0
SHD3_k127_832573_3 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 525.0
SHD3_k127_832573_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 480.0
SHD3_k127_832573_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 420.0
SHD3_k127_832573_6 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 410.0
SHD3_k127_832573_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 388.0
SHD3_k127_832573_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 334.0
SHD3_k127_832573_9 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 340.0
SHD3_k127_832609_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 520.0
SHD3_k127_832609_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 413.0
SHD3_k127_832609_2 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000009794 248.0
SHD3_k127_832609_3 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000000000002175 200.0
SHD3_k127_832609_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000006035 62.0
SHD3_k127_834616_0 Dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000001726 199.0
SHD3_k127_834616_1 DGC domain - - - 0.000000000000000115 82.0
SHD3_k127_835612_0 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 486.0
SHD3_k127_835612_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 404.0
SHD3_k127_835612_10 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000005418 118.0
SHD3_k127_835612_11 antisigma factor binding K04749,K05946,K06378 - 2.4.1.187 0.00000000000000009318 83.0
SHD3_k127_835612_12 PFAM Mammalian cell entry related K02067 - - 0.0000000000000003199 89.0
SHD3_k127_835612_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000001849 77.0
SHD3_k127_835612_14 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000608 53.0
SHD3_k127_835612_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 349.0
SHD3_k127_835612_3 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 340.0
SHD3_k127_835612_4 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 324.0
SHD3_k127_835612_5 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001188 277.0
SHD3_k127_835612_6 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002331 262.0
SHD3_k127_835612_7 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000001503 252.0
SHD3_k127_835612_8 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000000002417 198.0
SHD3_k127_835612_9 SPTR Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000006058 176.0
SHD3_k127_836836_0 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K07114 - - 0.00004708 53.0
SHD3_k127_838383_0 COG1064 Zn-dependent alcohol K13979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 542.0
SHD3_k127_838383_1 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0034641,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 374.0
SHD3_k127_838383_2 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 316.0
SHD3_k127_838383_3 - - - - 0.000000000000000000000000000000000000000000000000001087 192.0
SHD3_k127_838383_4 GYD domain - - - 0.000000000000000000000005111 106.0
SHD3_k127_838383_5 - - - - 0.0000000000000000000193 96.0
SHD3_k127_838383_6 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000002695 69.0
SHD3_k127_838383_7 - - - - 0.000000000004971 75.0
SHD3_k127_838383_8 lactoylglutathione lyase activity - - - 0.0002383 48.0
SHD3_k127_857981_0 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 416.0
SHD3_k127_857981_1 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000002161 196.0
SHD3_k127_8610_0 Glucodextranase, domain N K01178 - 3.2.1.3 2.76e-257 805.0
SHD3_k127_8610_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 488.0
SHD3_k127_8610_2 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 338.0
SHD3_k127_8610_3 Copper resistance protein CopZ K07213 - - 0.00002072 49.0
SHD3_k127_869340_0 L,D-transpeptidase catalytic domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 446.0
SHD3_k127_870967_0 Elements of external origin K07494 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 433.0
SHD3_k127_870967_1 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 426.0
SHD3_k127_875331_0 SMART Elongator protein 3 MiaB NifB - - - 1.196e-233 728.0
SHD3_k127_875331_1 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000007138 211.0
SHD3_k127_875331_2 Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000005529 139.0
SHD3_k127_875331_3 Domain of unknown function (DUF4833) - - - 0.000000000000000000002656 102.0
SHD3_k127_875331_4 Membrane - - - 0.00000000000000000001953 97.0
SHD3_k127_877912_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.534e-202 640.0
SHD3_k127_877912_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 596.0
SHD3_k127_877912_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000008048 159.0
SHD3_k127_877912_11 GDP-mannose 4,6 dehydratase K19180 - 1.1.1.339 0.000000000000000000000000000000000009102 150.0
SHD3_k127_877912_12 Amino acid permease - - - 0.00000000000000000009013 91.0
SHD3_k127_877912_2 PFAM outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 473.0
SHD3_k127_877912_3 Glycosyl transferase family 2 K00721,K20534 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 439.0
SHD3_k127_877912_4 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 437.0
SHD3_k127_877912_5 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 379.0
SHD3_k127_877912_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 370.0
SHD3_k127_877912_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 321.0
SHD3_k127_877912_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 288.0
SHD3_k127_877912_9 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000006311 215.0
SHD3_k127_880861_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 533.0
SHD3_k127_880861_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 482.0
SHD3_k127_880861_2 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 330.0
SHD3_k127_880861_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003169 252.0
SHD3_k127_880861_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000648 201.0
SHD3_k127_880861_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000001387 154.0
SHD3_k127_880861_6 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000001352 146.0
SHD3_k127_880861_7 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000002181 112.0
SHD3_k127_88581_0 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000003916 206.0
SHD3_k127_88581_1 Type II secretion system (T2SS), protein J K02459 - - 0.00000000000000000000000006968 115.0
SHD3_k127_88581_2 - - - - 0.00000000000000000000000402 112.0
SHD3_k127_88581_3 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000000000000001172 104.0
SHD3_k127_88581_4 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000000001145 79.0
SHD3_k127_88581_5 PFAM Phosphate-selective porin O and P - - - 0.000000000009319 66.0
SHD3_k127_88581_6 Prokaryotic N-terminal methylation motif K02458 - - 0.00000000008684 67.0
SHD3_k127_88581_8 Type II secretion system (T2SS), protein K K02460 - - 0.00000004955 64.0
SHD3_k127_889267_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1251.0
SHD3_k127_889267_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.697e-214 671.0
SHD3_k127_889267_10 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 388.0
SHD3_k127_889267_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 366.0
SHD3_k127_889267_12 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 342.0
SHD3_k127_889267_13 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 328.0
SHD3_k127_889267_14 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 325.0
SHD3_k127_889267_15 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002829 278.0
SHD3_k127_889267_16 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002373 272.0
SHD3_k127_889267_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006359 249.0
SHD3_k127_889267_18 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000001531 224.0
SHD3_k127_889267_19 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000003759 216.0
SHD3_k127_889267_2 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 608.0
SHD3_k127_889267_20 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000006399 216.0
SHD3_k127_889267_21 - - - - 0.0000000000000000000000000000000000000000000000000000006908 202.0
SHD3_k127_889267_22 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000000000000000001304 201.0
SHD3_k127_889267_23 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000001231 177.0
SHD3_k127_889267_24 membrane K00389 - - 0.000000000000000000000000000000000000000003503 159.0
SHD3_k127_889267_25 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000002276 149.0
SHD3_k127_889267_26 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000003686 136.0
SHD3_k127_889267_27 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000008491 128.0
SHD3_k127_889267_28 - - - - 0.000000000000000000000000188 106.0
SHD3_k127_889267_29 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000003027 103.0
SHD3_k127_889267_3 DHHA2 domain K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 576.0
SHD3_k127_889267_30 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000002749 96.0
SHD3_k127_889267_32 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000007365 81.0
SHD3_k127_889267_33 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000000000006889 74.0
SHD3_k127_889267_34 heat shock protein binding K03686 - - 0.0000000001991 73.0
SHD3_k127_889267_4 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 527.0
SHD3_k127_889267_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 507.0
SHD3_k127_889267_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 492.0
SHD3_k127_889267_7 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 449.0
SHD3_k127_889267_8 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 445.0
SHD3_k127_889267_9 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 403.0
SHD3_k127_890857_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 463.0
SHD3_k127_890857_1 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006867 284.0
SHD3_k127_890857_2 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000007244 223.0
SHD3_k127_890857_3 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000008203 178.0
SHD3_k127_890857_4 PFAM Response regulator receiver domain K02479 - - 0.00000005482 61.0
SHD3_k127_891970_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 300.0
SHD3_k127_891970_1 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000001818 165.0
SHD3_k127_891970_2 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000312 151.0
SHD3_k127_903792_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1244.0
SHD3_k127_903792_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002583 275.0
SHD3_k127_903792_2 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003046 278.0
SHD3_k127_903792_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001354 250.0
SHD3_k127_903792_4 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000571 238.0
SHD3_k127_903792_5 Histidine kinase-like ATPases - - - 0.00000000005817 74.0
SHD3_k127_903792_6 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.0000000001391 71.0
SHD3_k127_903792_7 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 - - 0.00003671 55.0
SHD3_k127_903792_8 OmpA family K02557 - - 0.0003521 51.0
SHD3_k127_908459_0 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005017 254.0
SHD3_k127_908459_1 PIN domain K07063 - - 0.00000000000000000000000000000000000307 141.0
SHD3_k127_908459_2 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000000006071 107.0
SHD3_k127_908459_3 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000001793 92.0
SHD3_k127_908459_4 SnoaL-like polyketide cyclase - - - 0.00000000000000002456 81.0
SHD3_k127_909141_0 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000004664 214.0
SHD3_k127_909141_1 TIGRFAM cytochrome C family protein - - - 0.00000000002535 74.0
SHD3_k127_909617_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000148 266.0
SHD3_k127_909617_1 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000000004046 230.0
SHD3_k127_909617_2 biopolymer transport protein - - - 0.0000000000000000000000000000000000000000000000000002764 189.0
SHD3_k127_913793_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1086.0
SHD3_k127_913793_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 4.768e-307 950.0
SHD3_k127_913793_10 - - - - 0.0000000000000009668 79.0
SHD3_k127_913793_11 Positive regulator of sigma(E), RseC MucC K03803 - - 0.0000007424 56.0
SHD3_k127_913793_12 diguanylate cyclase - - - 0.000007018 51.0
SHD3_k127_913793_2 Elongation factor G, domain IV K02355 - - 1.881e-296 923.0
SHD3_k127_913793_3 Glucose-1-phosphate thymidylyltransferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 433.0
SHD3_k127_913793_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 423.0
SHD3_k127_913793_5 PFAM Glutamine amidotransferase, class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 293.0
SHD3_k127_913793_6 Male sterility protein K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000064 268.0
SHD3_k127_913793_7 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009062 282.0
SHD3_k127_913793_8 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000005541 190.0
SHD3_k127_91730_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 7.273e-319 990.0
SHD3_k127_91730_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 396.0
SHD3_k127_91730_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 383.0
SHD3_k127_91730_4 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000001126 71.0
SHD3_k127_922985_0 - - - - 0.000000000000000002958 84.0
SHD3_k127_922985_1 - - - - 0.00000000000000007213 83.0
SHD3_k127_922985_2 - - - - 0.000000000000003219 75.0
SHD3_k127_922985_3 - - - - 0.0000000000007093 69.0
SHD3_k127_927331_0 lipolytic protein G-D-S-L family - - - 0.00000000000000000005654 103.0
SHD3_k127_927331_1 - - - - 0.000000000000002254 84.0
SHD3_k127_927331_2 self proteolysis - - - 0.0000000003077 72.0
SHD3_k127_927331_3 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000271 53.0
SHD3_k127_937823_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 571.0
SHD3_k127_937823_1 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009015 283.0
SHD3_k127_937823_2 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001143 160.0
SHD3_k127_937823_3 DsrE/DsrF/DrsH-like family - - - 0.00000003307 55.0
SHD3_k127_93883_0 PAS domain - - - 0.00000000000000000000000000000000000000000000000000001105 204.0
SHD3_k127_93883_1 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000002568 130.0
SHD3_k127_93883_2 Cyclophilin-like K09143 - - 0.0000000000000000003774 89.0
SHD3_k127_93883_3 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000009855 60.0
SHD3_k127_93883_4 toxin-antitoxin pair type II binding - - - 0.00000001712 57.0
SHD3_k127_941024_0 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 511.0
SHD3_k127_941024_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 398.0
SHD3_k127_94548_0 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 396.0
SHD3_k127_94548_1 Uncharacterised protein family (UPF0158) - - - 0.00000001276 63.0
SHD3_k127_946406_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 589.0
SHD3_k127_946406_1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 384.0
SHD3_k127_946406_2 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001941 267.0
SHD3_k127_94646_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.732e-263 829.0
SHD3_k127_94646_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 2.114e-243 774.0
SHD3_k127_94646_10 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001515 242.0
SHD3_k127_94646_11 HNH nucleases - - - 0.00000000000000000000000000000000000000000000001171 174.0
SHD3_k127_94646_12 mRNA catabolic process - - - 0.00000000000000000000000000000000000000000000008103 178.0
SHD3_k127_94646_13 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000002175 152.0
SHD3_k127_94646_14 TIGRFAM diguanylate cyclase - - - 0.0000000000000000000000000000000000002934 159.0
SHD3_k127_94646_15 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000002225 139.0
SHD3_k127_94646_16 Transcriptional regulator, MerR family - - - 0.0000000000000000000000000000000001958 137.0
SHD3_k127_94646_17 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000009998 126.0
SHD3_k127_94646_18 isomerase activity K01821 - 5.3.2.6 0.0000000000000000000000001572 109.0
SHD3_k127_94646_19 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000003009 107.0
SHD3_k127_94646_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.278e-196 617.0
SHD3_k127_94646_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000002821 97.0
SHD3_k127_94646_21 Diguanylate cyclase - - - 0.000000000000000000556 102.0
SHD3_k127_94646_22 GAF domain - - - 0.0000000000000001103 94.0
SHD3_k127_94646_24 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000002292 72.0
SHD3_k127_94646_26 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000000725 55.0
SHD3_k127_94646_27 conserved protein involved in oxidation of intracellular sulfur K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.0000532 49.0
SHD3_k127_94646_28 Histidine kinase K02660,K11525 - - 0.0002142 54.0
SHD3_k127_94646_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 603.0
SHD3_k127_94646_4 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 375.0
SHD3_k127_94646_5 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 338.0
SHD3_k127_94646_6 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 320.0
SHD3_k127_94646_7 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 292.0
SHD3_k127_94646_8 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001344 258.0
SHD3_k127_94646_9 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002958 244.0
SHD3_k127_946907_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1095.0
SHD3_k127_946907_1 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 483.0
SHD3_k127_946907_10 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000006448 154.0
SHD3_k127_946907_11 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000004445 153.0
SHD3_k127_946907_12 response regulator - - - 0.0000000000000000000000000000000004529 143.0
SHD3_k127_946907_13 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000001615 129.0
SHD3_k127_946907_15 Regulatory protein, FmdB family - - - 0.000000003321 59.0
SHD3_k127_946907_16 Resolvase - - - 0.0000002775 53.0
SHD3_k127_946907_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 363.0
SHD3_k127_946907_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 327.0
SHD3_k127_946907_4 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000007474 241.0
SHD3_k127_946907_5 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000003645 228.0
SHD3_k127_946907_6 ABC 3 transport family K09816,K09819 - - 0.000000000000000000000000000000000000000000000000000000002033 209.0
SHD3_k127_946907_7 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000263 198.0
SHD3_k127_946907_8 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000001187 192.0
SHD3_k127_946907_9 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000000000000004659 152.0
SHD3_k127_95369_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 1.11e-248 787.0
SHD3_k127_95369_1 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 1.048e-220 699.0
SHD3_k127_95369_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 362.0
SHD3_k127_95369_3 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000004107 232.0
SHD3_k127_95369_4 UPF0489 domain - - - 0.000000000000000000000000000001307 123.0
SHD3_k127_95369_5 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000001598 69.0
SHD3_k127_95369_6 Addiction module toxin RelE StbE family - - - 0.00000000001306 68.0
SHD3_k127_96554_0 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000005108 160.0
SHD3_k127_96554_1 the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - 0.00000000000000000000009695 100.0
SHD3_k127_96554_2 - - - - 0.0000000000001418 72.0
SHD3_k127_96554_3 - - - - 0.00000397 49.0
SHD3_k127_967711_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 447.0
SHD3_k127_967711_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 370.0
SHD3_k127_967711_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 320.0
SHD3_k127_967711_3 Stage II sporulation protein M - - - 0.0000000000000000000000000004019 121.0
SHD3_k127_967711_4 DsrE/DsrF-like family - - - 0.00000001203 56.0
SHD3_k127_967735_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1118.0
SHD3_k127_967735_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 1.027e-205 675.0
SHD3_k127_967735_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00001436 49.0
SHD3_k127_967735_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 376.0
SHD3_k127_967735_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000007599 221.0
SHD3_k127_967735_4 GAF domain - - - 0.000000000000000000000000000000000000000000003182 179.0
SHD3_k127_967735_6 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000005675 74.0
SHD3_k127_967735_7 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000003941 80.0
SHD3_k127_967735_8 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000003584 64.0
SHD3_k127_967735_9 DsrE/DsrF-like family - - - 0.00000001203 56.0
SHD3_k127_968552_0 Pyruvate phosphate dikinase, PEP K01006 - 2.7.9.1 0.0 1457.0
SHD3_k127_968552_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 559.0
SHD3_k127_968552_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 377.0
SHD3_k127_968552_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 318.0
SHD3_k127_968552_4 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000001309 196.0
SHD3_k127_968552_5 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000000000000001274 163.0
SHD3_k127_968552_6 DNA-binding protein VF530 - - - 0.000000000000000000000000000009006 119.0
SHD3_k127_968552_7 PilZ domain - - - 0.0002886 50.0
SHD3_k127_968552_8 PFAM Transposase IS200 like - - - 0.0002926 46.0
SHD3_k127_975769_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.223e-278 869.0
SHD3_k127_975769_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 530.0
SHD3_k127_975769_2 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 529.0
SHD3_k127_975769_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001642 278.0
SHD3_k127_975769_4 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000004562 243.0
SHD3_k127_975769_5 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.000000000000000000000000000000000001314 144.0
SHD3_k127_975769_6 - - - - 0.0000001829 55.0
SHD3_k127_983260_0 - - - - 0.0000000000000369 72.0
SHD3_k127_983260_1 - - - - 0.00000002186 59.0