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Overview

ID MAG03395
Name SHD3_bin.5
Sample SMP0084
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Limnocylindria
Order Limnocylindrales
Family CSP1-4
Genus UBA5189
Species
Assembly information
Completeness (%) 86.57
Contamination (%) 0.7
GC content (%) 72.0
N50 (bp) 14,214
Genome size (bp) 2,113,517

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1859

Gene name Description KEGG GOs EC E-value Score Sequence
SHD3_k127_1000689_0 GMC oxidoreductase K00108 - 1.1.99.1 5.515e-271 845.0
SHD3_k127_1000689_1 Type II/IV secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 535.0
SHD3_k127_1000689_10 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000003217 201.0
SHD3_k127_1000689_11 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000001111 205.0
SHD3_k127_1000689_12 typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000001442 183.0
SHD3_k127_1000689_13 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000004153 179.0
SHD3_k127_1000689_14 WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000002286 173.0
SHD3_k127_1000689_15 Response regulator receiver - - - 0.000000000000000000000000000000000004523 146.0
SHD3_k127_1000689_16 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000001799 145.0
SHD3_k127_1000689_17 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000001425 140.0
SHD3_k127_1000689_18 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000001714 126.0
SHD3_k127_1000689_19 Pfam Cation efflux - - - 0.00000000000000000000000009731 119.0
SHD3_k127_1000689_2 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 478.0
SHD3_k127_1000689_20 FMN-binding domain protein - - - 0.00000000000000000001113 101.0
SHD3_k127_1000689_21 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000006832 100.0
SHD3_k127_1000689_22 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000432 89.0
SHD3_k127_1000689_23 domain, Protein - - - 0.00000009571 64.0
SHD3_k127_1000689_24 anaerobic respiration - - - 0.00007612 53.0
SHD3_k127_1000689_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 464.0
SHD3_k127_1000689_4 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 400.0
SHD3_k127_1000689_5 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004929 276.0
SHD3_k127_1000689_6 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000006606 256.0
SHD3_k127_1000689_7 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007719 259.0
SHD3_k127_1000689_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000003596 227.0
SHD3_k127_1000689_9 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000001337 225.0
SHD3_k127_1003514_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 9.207e-249 807.0
SHD3_k127_1003514_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 444.0
SHD3_k127_1003514_10 COG1305 Transglutaminase-like enzymes - - - 0.0000000000000000000000003549 121.0
SHD3_k127_1003514_11 Belongs to the phosphoglycerate mutase family - - - 0.000000000000000000000005791 112.0
SHD3_k127_1003514_12 nuclear chromosome segregation - - - 0.0000000000000000008333 93.0
SHD3_k127_1003514_13 haloacid dehalogenase K07025 - - 0.00000000000004363 84.0
SHD3_k127_1003514_14 Histidine kinase - - - 0.00000000003241 77.0
SHD3_k127_1003514_15 histidine kinase A domain protein - - - 0.000003149 61.0
SHD3_k127_1003514_16 helix_turn_helix, Lux Regulon K07684 - - 0.00001073 57.0
SHD3_k127_1003514_2 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 390.0
SHD3_k127_1003514_3 ABC transporter substrate-binding protein K10232 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 369.0
SHD3_k127_1003514_4 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009064 296.0
SHD3_k127_1003514_5 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001355 270.0
SHD3_k127_1003514_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000004481 219.0
SHD3_k127_1003514_7 helix_turn_helix, Lux Regulon K02479 - - 0.00000000000000000000000000000000000000000000000000000002946 214.0
SHD3_k127_1003514_8 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000001057 214.0
SHD3_k127_1003514_9 Methyltransferase type 12 - - - 0.0000000000000000000000000000004667 133.0
SHD3_k127_1012404_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 549.0
SHD3_k127_1012404_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 495.0
SHD3_k127_1012404_2 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 426.0
SHD3_k127_1012404_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 347.0
SHD3_k127_1012404_4 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 346.0
SHD3_k127_1012404_5 Rifampin ADP-ribosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004994 241.0
SHD3_k127_1012404_6 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000000000000000000000000000000000000000000002242 191.0
SHD3_k127_1012404_7 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000002679 184.0
SHD3_k127_1012404_8 - K11477 - - 0.00000000000000000000000000001108 123.0
SHD3_k127_1012404_9 - - - - 0.0000000000001324 81.0
SHD3_k127_1020810_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003059 275.0
SHD3_k127_1020810_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000001198 181.0
SHD3_k127_1020810_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000007351 135.0
SHD3_k127_1020810_3 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000006059 126.0
SHD3_k127_1020810_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000003823 118.0
SHD3_k127_1020810_5 - - - - 0.000000000000000007295 84.0
SHD3_k127_1020810_6 DNA polymerase III K02340 - 2.7.7.7 0.000000003894 69.0
SHD3_k127_1020810_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00002636 55.0
SHD3_k127_103019_0 AP endonuclease family 2 C terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 488.0
SHD3_k127_103019_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 362.0
SHD3_k127_103019_2 DeoC/LacD family aldolase K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 289.0
SHD3_k127_103019_3 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001006 280.0
SHD3_k127_1030873_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 3.015e-195 623.0
SHD3_k127_1030873_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 449.0
SHD3_k127_1030873_10 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000008529 92.0
SHD3_k127_1030873_2 carbohydrate transport K17315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 391.0
SHD3_k127_1030873_3 Binding-protein-dependent transport system inner membrane component K02026,K17317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 359.0
SHD3_k127_1030873_4 COG1175 ABC-type sugar transport systems, permease components K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 329.0
SHD3_k127_1030873_5 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 307.0
SHD3_k127_1030873_6 PFAM acyl-CoA dehydrogenase domain protein K00248,K18244 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 289.0
SHD3_k127_1030873_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000001117 241.0
SHD3_k127_1030873_8 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000001079 123.0
SHD3_k127_1030873_9 Polysaccharide deacetylase - - - 0.0000000000000000000000004407 122.0
SHD3_k127_105946_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.774e-228 738.0
SHD3_k127_105946_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 375.0
SHD3_k127_105946_2 cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 369.0
SHD3_k127_105946_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 308.0
SHD3_k127_105946_4 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000003538 241.0
SHD3_k127_105946_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000288 230.0
SHD3_k127_105946_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000004502 141.0
SHD3_k127_105946_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000001525 86.0
SHD3_k127_105946_8 Baseplate J-like protein K01218 - 3.2.1.78 0.00001016 59.0
SHD3_k127_1088540_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 9.889e-283 888.0
SHD3_k127_1088540_1 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 381.0
SHD3_k127_1088540_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859,K07566 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 0.00000000000000000000000000000000000000002371 162.0
SHD3_k127_1088540_3 TIGRFAM Flp pilus assembly protein CpaB K02279 - - 0.00005058 54.0
SHD3_k127_1110614_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 512.0
SHD3_k127_1110614_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 482.0
SHD3_k127_1110614_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000729 200.0
SHD3_k127_1110614_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000001378 192.0
SHD3_k127_1110614_4 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000904 145.0
SHD3_k127_1110614_5 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.0000000000000000000009772 97.0
SHD3_k127_1131565_0 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000001176 243.0
SHD3_k127_1131565_1 ABC transporter K02049,K10831 - 3.6.3.36 0.0000000000000000000000000000000000000000000000000000000000000005173 230.0
SHD3_k127_1131565_10 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000002485 109.0
SHD3_k127_1131565_11 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000001466 109.0
SHD3_k127_1131565_12 domain, Protein - - - 0.0000002924 63.0
SHD3_k127_1131565_13 - - - - 0.0001281 50.0
SHD3_k127_1131565_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000005124 222.0
SHD3_k127_1131565_3 Involved in multi-copper enzyme maturation, permease component - - - 0.0000000000000000000000000000000000000000000000000004581 194.0
SHD3_k127_1131565_4 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000001074 190.0
SHD3_k127_1131565_5 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000001782 193.0
SHD3_k127_1131565_6 HhH-GPD superfamily base excision DNA repair protein - - - 0.000000000000000000000000000000000000000003143 161.0
SHD3_k127_1131565_7 Transcriptional regulator - - - 0.000000000000000000000000000000001077 142.0
SHD3_k127_1131565_8 - - - - 0.00000000000000000000000001282 119.0
SHD3_k127_1131565_9 Protein of unknown function (DUF2089) - - - 0.000000000000000000000002111 108.0
SHD3_k127_1155387_0 DNA primase, small subunit K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 603.0
SHD3_k127_1155387_1 belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 454.0
SHD3_k127_1155387_10 Protein of unknown function (DUF1706) - - - 0.000005975 57.0
SHD3_k127_1155387_2 ATP dependent DNA ligase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 421.0
SHD3_k127_1155387_3 ABC 3 transport family K09819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004169 253.0
SHD3_k127_1155387_4 ATPases associated with a variety of cellular activities K09820 - - 0.000000000000000000000000000000000000000000000000000000000000009102 234.0
SHD3_k127_1155387_5 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000001568 212.0
SHD3_k127_1155387_6 YCII-related domain - - - 0.0000000000000000000000000000000000004777 144.0
SHD3_k127_1155387_7 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000001716 123.0
SHD3_k127_1155387_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000005863 112.0
SHD3_k127_1155387_9 Sigma-70, region 4 K03088 - - 0.0000000000007099 77.0
SHD3_k127_1241973_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000003351 192.0
SHD3_k127_1241973_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000001069 73.0
SHD3_k127_1241973_2 Belongs to the UPF0235 family K09131 - - 0.00000000002175 75.0
SHD3_k127_126310_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.000000000000000000000000000000000000000001212 159.0
SHD3_k127_126310_2 Hemerythrin HHE cation binding domain - - - 0.0009954 50.0
SHD3_k127_127372_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1363.0
SHD3_k127_127372_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 300.0
SHD3_k127_127372_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000006823 213.0
SHD3_k127_127372_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000006416 204.0
SHD3_k127_127372_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000001653 156.0
SHD3_k127_127372_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000009884 112.0
SHD3_k127_1305981_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 4.315e-272 858.0
SHD3_k127_1305981_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 337.0
SHD3_k127_1305981_2 PFAM sodium calcium exchanger K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001022 259.0
SHD3_k127_1305981_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000005816 206.0
SHD3_k127_1305981_4 cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000000003001 177.0
SHD3_k127_1305981_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000005167 121.0
SHD3_k127_1305981_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000007581 109.0
SHD3_k127_1305981_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000001104 94.0
SHD3_k127_1359199_0 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 482.0
SHD3_k127_1359199_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 428.0
SHD3_k127_1359199_2 L-phenylalanine transmembrane transporter activity K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 424.0
SHD3_k127_1359199_3 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 384.0
SHD3_k127_1359199_4 branched-chain amino acid transmembrane transporter activity K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 316.0
SHD3_k127_1359199_5 ABC-type branched-chain amino acid transport systems, periplasmic component K01999,K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 288.0
SHD3_k127_1359199_6 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995,K11957 - - 0.0000000000000000000000000000000000926 143.0
SHD3_k127_1359199_7 spore germination - - - 0.000000000004851 77.0
SHD3_k127_1359199_8 kinase activity K01007 - 2.7.9.2 0.000000000272 64.0
SHD3_k127_1399753_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 3.154e-200 643.0
SHD3_k127_1399753_1 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 360.0
SHD3_k127_1399753_10 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000002824 151.0
SHD3_k127_1399753_11 Domain present in phytochromes and cGMP-specific phosphodiesterases. K18350 - 2.7.13.3 0.000000000000000000000000000003555 139.0
SHD3_k127_1399753_12 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.0000000000000000000001455 104.0
SHD3_k127_1399753_13 Transcriptional regulator, TraR DksA family K06204 - - 0.0000000000000003587 82.0
SHD3_k127_1399753_14 exo-alpha-(2->6)-sialidase activity - - - 0.0000002031 63.0
SHD3_k127_1399753_15 abc transporter atp-binding protein K06147 - - 0.0000006247 53.0
SHD3_k127_1399753_2 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 330.0
SHD3_k127_1399753_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 325.0
SHD3_k127_1399753_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002107 259.0
SHD3_k127_1399753_5 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000003912 204.0
SHD3_k127_1399753_6 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000001367 178.0
SHD3_k127_1399753_7 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351,K07245 - - 0.0000000000000000000000000000000000000000009347 180.0
SHD3_k127_1399753_8 Heme copper-type cytochrome quinol oxidase subunit 3 K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000006281 154.0
SHD3_k127_1399753_9 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000001508 154.0
SHD3_k127_1440731_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 597.0
SHD3_k127_1440731_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 562.0
SHD3_k127_1440731_10 - - - - 0.00002615 54.0
SHD3_k127_1440731_11 Colicin V production protein K03558 - - 0.00002827 55.0
SHD3_k127_1440731_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 496.0
SHD3_k127_1440731_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 355.0
SHD3_k127_1440731_4 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001786 266.0
SHD3_k127_1440731_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000001776 186.0
SHD3_k127_1440731_6 alkylbase DNA N-glycosylase activity K03652 - 3.2.2.21 0.000000000000000000000000000000000000001989 157.0
SHD3_k127_1440731_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000008052 136.0
SHD3_k127_1440731_8 metallopeptidase activity - - - 0.00000000002564 69.0
SHD3_k127_1440731_9 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000657 67.0
SHD3_k127_1454204_0 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 440.0
SHD3_k127_1454204_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000003904 198.0
SHD3_k127_1454204_2 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000004047 198.0
SHD3_k127_1454204_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000004047 156.0
SHD3_k127_1454204_4 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000003713 98.0
SHD3_k127_1485170_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 578.0
SHD3_k127_1485170_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 518.0
SHD3_k127_1485170_10 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001534 261.0
SHD3_k127_1485170_11 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000006323 236.0
SHD3_k127_1485170_12 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000005855 203.0
SHD3_k127_1485170_13 ATPase activity K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000002923 205.0
SHD3_k127_1485170_14 phosphorelay sensor kinase activity K16923,K18967 - 2.7.7.65 0.000000000000000000000000000000000000004347 161.0
SHD3_k127_1485170_15 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000001517 150.0
SHD3_k127_1485170_16 PFAM NUDIX domain - - - 0.00000000000000000000000000000000004765 147.0
SHD3_k127_1485170_18 PFAM Cobalt transport protein K16785 - - 0.0000000000000000000000000003845 124.0
SHD3_k127_1485170_19 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000000004068 111.0
SHD3_k127_1485170_2 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 498.0
SHD3_k127_1485170_20 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.000000000000000004508 96.0
SHD3_k127_1485170_21 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000008394 64.0
SHD3_k127_1485170_3 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 424.0
SHD3_k127_1485170_4 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 399.0
SHD3_k127_1485170_5 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 337.0
SHD3_k127_1485170_6 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 300.0
SHD3_k127_1485170_7 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 302.0
SHD3_k127_1485170_8 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 311.0
SHD3_k127_1485170_9 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000165 277.0
SHD3_k127_1521360_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000002276 199.0
SHD3_k127_1521360_1 transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000003839 175.0
SHD3_k127_1521360_2 Major facilitator superfamily - - - 0.00000002768 65.0
SHD3_k127_1547286_0 FAD dependent oxidoreductase central domain - - - 0.0 1081.0
SHD3_k127_1547286_1 Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 593.0
SHD3_k127_1547286_10 Haloacid dehalogenase-like hydrolase family protein. Source PGD - - - 0.000000000000000000000000000000000000001568 157.0
SHD3_k127_1547286_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 474.0
SHD3_k127_1547286_3 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 462.0
SHD3_k127_1547286_4 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 449.0
SHD3_k127_1547286_5 metallophosphoesterase K07096,K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 366.0
SHD3_k127_1547286_6 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 358.0
SHD3_k127_1547286_7 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003809 265.0
SHD3_k127_1547286_8 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000001175 229.0
SHD3_k127_1547286_9 - - - - 0.00000000000000000000000000000000000000000000000001516 196.0
SHD3_k127_154905_0 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 398.0
SHD3_k127_154905_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 347.0
SHD3_k127_154905_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 295.0
SHD3_k127_154905_3 Belongs to the peptidase S51 family - - - 0.00000000000000000000000000000000000000000000000000000000000006408 221.0
SHD3_k127_1563495_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 6.203e-234 744.0
SHD3_k127_1563495_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 1.176e-207 651.0
SHD3_k127_1563495_2 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001489 251.0
SHD3_k127_1563495_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000001082 229.0
SHD3_k127_1563495_4 MOSC domain containing protein K07140 - - 0.0000000000000000000000000000000000000000000000008782 186.0
SHD3_k127_1584315_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.465e-239 768.0
SHD3_k127_1584315_1 elongation factor Tu domain 2 protein K06207 - - 1.472e-215 687.0
SHD3_k127_1584315_10 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000000000000000000000000000000000003334 236.0
SHD3_k127_1584315_11 PFAM DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000001023 190.0
SHD3_k127_1584315_12 NUBPL iron-transfer P-loop NTPase K02282 - - 0.000000000000000000000000000000000000000000000002307 188.0
SHD3_k127_1584315_13 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000008466 137.0
SHD3_k127_1584315_15 Protein of unknown function (DUF1624) - - - 0.000000000000000000000001199 120.0
SHD3_k127_1584315_16 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000009913 102.0
SHD3_k127_1584315_17 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000001123 63.0
SHD3_k127_1584315_18 - - - - 0.000001929 56.0
SHD3_k127_1584315_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.61e-199 640.0
SHD3_k127_1584315_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 610.0
SHD3_k127_1584315_4 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 397.0
SHD3_k127_1584315_5 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 339.0
SHD3_k127_1584315_6 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 337.0
SHD3_k127_1584315_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008398 291.0
SHD3_k127_1584315_8 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007795 276.0
SHD3_k127_1584315_9 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008676 233.0
SHD3_k127_1609927_0 dead DEAH box helicase K03724 - - 2.775e-253 800.0
SHD3_k127_1609927_1 Protein of unknown function, DUF255 K06888 - - 1.589e-221 707.0
SHD3_k127_1609927_10 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000005981 128.0
SHD3_k127_1609927_11 NUDIX hydrolase - - - 0.0000000000000000000000001212 119.0
SHD3_k127_1609927_12 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000007564 96.0
SHD3_k127_1609927_2 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 563.0
SHD3_k127_1609927_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 375.0
SHD3_k127_1609927_4 acetoin utilization protein K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 316.0
SHD3_k127_1609927_5 DoxX K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000000000000000211 221.0
SHD3_k127_1609927_6 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000008634 184.0
SHD3_k127_1609927_7 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000003136 164.0
SHD3_k127_1609927_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000008893 142.0
SHD3_k127_1609927_9 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000001967 137.0
SHD3_k127_1615048_0 Belongs to the N(4) N(6)-methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 327.0
SHD3_k127_1615048_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 320.0
SHD3_k127_1615048_2 Cys/Met metabolism PLP-dependent enzyme K11325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000231 278.0
SHD3_k127_1615048_3 Threonyl alanyl tRNA synthetase SAD K01872,K07050 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001648 259.0
SHD3_k127_1615048_4 Zn-dependent metallo-hydrolase RNA specificity domain K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000001409 229.0
SHD3_k127_1615048_5 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000002862 228.0
SHD3_k127_1615048_6 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000003196 203.0
SHD3_k127_1615048_7 Cytochrome c554 and c-prime K03620 - - 0.000008213 55.0
SHD3_k127_1736263_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000005341 190.0
SHD3_k127_1736263_1 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000001607 176.0
SHD3_k127_1736263_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000003581 161.0
SHD3_k127_1776429_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 426.0
SHD3_k127_1776429_1 ADP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000004513 248.0
SHD3_k127_1815516_0 ABC-type sugar transport system, ATPase component K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 586.0
SHD3_k127_1815516_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416,K21417 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 591.0
SHD3_k127_1815516_2 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 323.0
SHD3_k127_1815516_3 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 296.0
SHD3_k127_1815516_4 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004538 300.0
SHD3_k127_1815516_5 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000001364 262.0
SHD3_k127_1815516_6 Amidohydrolase family K01443,K16786,K16787 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000001688 233.0
SHD3_k127_1815516_7 phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000007954 218.0
SHD3_k127_1815516_8 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000004019 205.0
SHD3_k127_1815516_9 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000003004 205.0
SHD3_k127_1821256_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 9.388e-300 953.0
SHD3_k127_1821256_1 Helix-hairpin-helix DNA-binding, class 1 K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 481.0
SHD3_k127_1821256_10 Diguanylate cyclase - - - 0.0000000000000000000000000000000356 143.0
SHD3_k127_1821256_11 cheY-homologous receiver domain - - - 0.00000000000000000000001711 116.0
SHD3_k127_1821256_12 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000002438 74.0
SHD3_k127_1821256_2 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 374.0
SHD3_k127_1821256_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 366.0
SHD3_k127_1821256_4 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 362.0
SHD3_k127_1821256_5 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 353.0
SHD3_k127_1821256_6 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 347.0
SHD3_k127_1821256_7 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000001436 287.0
SHD3_k127_1821256_8 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000001894 233.0
SHD3_k127_1821256_9 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000001407 162.0
SHD3_k127_1827922_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 597.0
SHD3_k127_1827922_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 557.0
SHD3_k127_1856061_0 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000001076 233.0
SHD3_k127_1856061_1 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000001847 193.0
SHD3_k127_1856061_2 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000005326 150.0
SHD3_k127_1903965_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 2.132e-249 799.0
SHD3_k127_1903965_1 Cysteine-rich secretory protein family - - - 0.00000269 55.0
SHD3_k127_1904377_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 381.0
SHD3_k127_1904377_1 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 381.0
SHD3_k127_1904377_10 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000007122 94.0
SHD3_k127_1904377_11 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000001405 104.0
SHD3_k127_1904377_12 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000001407 92.0
SHD3_k127_1904377_13 - - - - 0.00006464 55.0
SHD3_k127_1904377_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 310.0
SHD3_k127_1904377_3 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001286 241.0
SHD3_k127_1904377_4 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000009055 207.0
SHD3_k127_1904377_5 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000002054 193.0
SHD3_k127_1904377_6 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000007007 169.0
SHD3_k127_1904377_7 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.00000000000000000000000000000000000002933 152.0
SHD3_k127_1904377_8 Glycosyl transferases group 1 - - - 0.000000000000000000000000000002124 130.0
SHD3_k127_1904377_9 Methyltransferase domain - - - 0.0000000000000000000002105 110.0
SHD3_k127_1936724_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 3.292e-240 752.0
SHD3_k127_1936724_1 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 451.0
SHD3_k127_1943861_0 Carbamoyl-phosphate synthase K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 4.592e-281 904.0
SHD3_k127_1943861_1 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 437.0
SHD3_k127_1943861_2 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 341.0
SHD3_k127_1943861_3 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000003782 214.0
SHD3_k127_1943861_4 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000002845 97.0
SHD3_k127_1943861_5 PFAM TadE family protein - - - 0.000000003873 68.0
SHD3_k127_1943861_6 Putative Flp pilus-assembly TadE/G-like - - - 0.000001906 61.0
SHD3_k127_1991921_0 Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 505.0
SHD3_k127_1991921_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 331.0
SHD3_k127_1991921_10 Molybdopterin oxidoreductase K00123 - 1.17.1.9 0.0000000000000000000000003612 109.0
SHD3_k127_1991921_11 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000000000005013 89.0
SHD3_k127_1991921_12 Putative lumazine-binding - - - 0.00000000000000000005824 89.0
SHD3_k127_1991921_13 acetyltransferase - - - 0.000000000000000001105 99.0
SHD3_k127_1991921_14 Cupin domain - - - 0.00000000000008967 76.0
SHD3_k127_1991921_15 UbiA prenyltransferase family - - - 0.0000000000002017 82.0
SHD3_k127_1991921_16 PFAM WD40-like beta Propeller - - - 0.00000000002697 76.0
SHD3_k127_1991921_17 Dolichol kinase K18678 GO:0003674,GO:0003824,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0006766,GO:0006775,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0010276,GO:0016101,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017144,GO:0018130,GO:0033306,GO:0034308,GO:0042360,GO:0042362,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1903173 2.7.1.182 0.0000000002291 71.0
SHD3_k127_1991921_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009228 288.0
SHD3_k127_1991921_3 kinase activity K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004489 296.0
SHD3_k127_1991921_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003174 269.0
SHD3_k127_1991921_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001353 255.0
SHD3_k127_1991921_6 Protein of unknown function (DUF3419) K13622 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004599 254.0
SHD3_k127_1991921_7 DinB superfamily - - - 0.000000000000000000000000000000000000000000001226 171.0
SHD3_k127_1991921_8 Translation elongation factor K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.0000000000000000000000000000000000005975 141.0
SHD3_k127_1991921_9 PFAM AMP-dependent synthetase and ligase K22319 - 6.1.3.1 0.0000000000000000000000000000000000218 155.0
SHD3_k127_2011773_0 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 411.0
SHD3_k127_2011773_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000003277 247.0
SHD3_k127_2045859_0 peptidase K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 368.0
SHD3_k127_2045859_1 Mur ligase middle domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 334.0
SHD3_k127_2045859_2 L-valine transmembrane transporter activity - - - 0.0000000000000000000000000001082 126.0
SHD3_k127_2045859_3 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000001553 110.0
SHD3_k127_2045859_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000007387 94.0
SHD3_k127_204992_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 1.658e-220 706.0
SHD3_k127_204992_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 432.0
SHD3_k127_204992_10 PFAM CHAD domain containing protein - - - 0.0000000000000000000000002462 120.0
SHD3_k127_204992_11 dna ligase K01971 - 6.5.1.1 0.0000000000000000000004685 106.0
SHD3_k127_204992_12 Protein of unknown function (DUF971) - - - 0.00000000000000003212 94.0
SHD3_k127_204992_13 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000001147 85.0
SHD3_k127_204992_14 - - - - 0.00000596 55.0
SHD3_k127_204992_15 CHAD - - - 0.00005748 53.0
SHD3_k127_204992_16 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00005781 55.0
SHD3_k127_204992_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 427.0
SHD3_k127_204992_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 400.0
SHD3_k127_204992_4 PFAM Prolyl oligopeptidase family K01303 - 3.4.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 363.0
SHD3_k127_204992_5 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009587 277.0
SHD3_k127_204992_6 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000006277 168.0
SHD3_k127_204992_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000727 154.0
SHD3_k127_204992_8 Potassium ABC transporter permease K01992 - - 0.000000000000000000000000000000000422 149.0
SHD3_k127_204992_9 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000301 150.0
SHD3_k127_2051491_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 7.535e-232 739.0
SHD3_k127_2051491_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 2.179e-210 674.0
SHD3_k127_2051491_10 NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 289.0
SHD3_k127_2051491_11 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000001713 257.0
SHD3_k127_2051491_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008324 241.0
SHD3_k127_2051491_13 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000213 237.0
SHD3_k127_2051491_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000003737 208.0
SHD3_k127_2051491_15 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000112 192.0
SHD3_k127_2051491_16 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000005707 178.0
SHD3_k127_2051491_17 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000002955 172.0
SHD3_k127_2051491_18 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000007518 153.0
SHD3_k127_2051491_19 EthD domain - - - 0.00000000000000000000000000000005046 128.0
SHD3_k127_2051491_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 2.25e-201 642.0
SHD3_k127_2051491_20 4Fe-4S dicluster domain - - - 0.00000000000000000000000001158 122.0
SHD3_k127_2051491_21 DsrE/DsrF-like family - - - 0.0000000000000000000004411 102.0
SHD3_k127_2051491_22 Histidine kinase - - - 0.0000000000000000000005612 100.0
SHD3_k127_2051491_23 Belongs to the sulfur carrier protein TusA family - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000000000000001488 87.0
SHD3_k127_2051491_24 Transcriptional regulator - - - 0.0000000000000002345 83.0
SHD3_k127_2051491_25 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000002056 86.0
SHD3_k127_2051491_26 Cbs domain - - - 0.0000000000001786 78.0
SHD3_k127_2051491_27 spore germination K03605 - - 0.0000000000002485 77.0
SHD3_k127_2051491_28 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000001334 74.0
SHD3_k127_2051491_29 PFAM amino acid-binding ACT domain protein - - - 0.00000672 56.0
SHD3_k127_2051491_3 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 586.0
SHD3_k127_2051491_30 Hydrogenase expression formation protein hupF K04653 - - 0.0004608 48.0
SHD3_k127_2051491_4 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 478.0
SHD3_k127_2051491_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 469.0
SHD3_k127_2051491_6 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 446.0
SHD3_k127_2051491_7 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 396.0
SHD3_k127_2051491_8 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 327.0
SHD3_k127_2051491_9 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 308.0
SHD3_k127_2075952_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.715e-261 825.0
SHD3_k127_2075952_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 439.0
SHD3_k127_2075952_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000005319 163.0
SHD3_k127_2075952_11 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000001148 117.0
SHD3_k127_2075952_12 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000000000004331 119.0
SHD3_k127_2075952_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 459.0
SHD3_k127_2075952_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 419.0
SHD3_k127_2075952_4 tRNA binding K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 398.0
SHD3_k127_2075952_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004731 301.0
SHD3_k127_2075952_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003704 284.0
SHD3_k127_2075952_7 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004439 306.0
SHD3_k127_2075952_8 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000002257 213.0
SHD3_k127_2075952_9 Glutamine amidotransferase of anthranilate synthase K01658,K01664 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000006692 211.0
SHD3_k127_2111884_0 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 400.0
SHD3_k127_2111884_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 364.0
SHD3_k127_2111884_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 342.0
SHD3_k127_2111884_3 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K09699 - 2.3.1.12,2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 322.0
SHD3_k127_2111884_4 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000581 240.0
SHD3_k127_2111884_5 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000001601 229.0
SHD3_k127_2111884_6 COGs COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000002707 173.0
SHD3_k127_2111884_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000006144 147.0
SHD3_k127_2111884_8 Transcriptional regulator - - - 0.000000000000000001214 89.0
SHD3_k127_2131439_0 COG0608 Single-stranded DNA-specific exonuclease K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001182 266.0
SHD3_k127_2131439_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000002016 210.0
SHD3_k127_2157402_0 Alcohol dehydrogenase GroES-like domain K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 510.0
SHD3_k127_2157402_1 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 497.0
SHD3_k127_2157402_10 spore germination - - - 0.00000000000000000000000000000000000000000008211 176.0
SHD3_k127_2157402_11 carboxylic ester hydrolase activity K08680 - 4.2.99.20 0.000000000000000000000000000000000001382 148.0
SHD3_k127_2157402_12 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000001724 103.0
SHD3_k127_2157402_13 Protein of unknown function (DUF3105) - - - 0.000000000000000001681 96.0
SHD3_k127_2157402_14 - - - - 0.00000000000006282 83.0
SHD3_k127_2157402_15 CarboxypepD_reg-like domain K13276 - - 0.00000000008895 74.0
SHD3_k127_2157402_16 Methyltransferase domain - - - 0.0006995 49.0
SHD3_k127_2157402_2 Cys/Met metabolism PLP-dependent enzyme K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 474.0
SHD3_k127_2157402_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 349.0
SHD3_k127_2157402_4 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000143 291.0
SHD3_k127_2157402_5 Pterin binding enzyme K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002623 282.0
SHD3_k127_2157402_6 periplasmic binding protein LacI transcriptional regulator K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000009856 265.0
SHD3_k127_2157402_7 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000001668 261.0
SHD3_k127_2157402_8 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000002871 230.0
SHD3_k127_2157402_9 PDZ domain (Also known as DHR or GLGF) - - - 0.000000000000000000000000000000000000000000000000000000000002251 226.0
SHD3_k127_2184161_0 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 328.0
SHD3_k127_2184161_1 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000001475 234.0
SHD3_k127_2184161_2 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000001231 123.0
SHD3_k127_2201778_0 ATPases associated with a variety of cellular activities K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 371.0
SHD3_k127_2201778_1 PFAM oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 283.0
SHD3_k127_2201778_2 Binding-protein-dependent transport system inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000000000000861 211.0
SHD3_k127_2201778_3 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000001071 188.0
SHD3_k127_2201778_4 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000000000002128 181.0
SHD3_k127_2201778_5 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 - - 0.00000000000000000000000000000000000000002565 165.0
SHD3_k127_2201778_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000006738 126.0
SHD3_k127_2201778_7 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000005073 103.0
SHD3_k127_2201778_8 PFAM Kelch repeat type 1 K03529 - - 0.000009481 58.0
SHD3_k127_2201778_9 TIGRFAM redox-active disulfide protein 2 - - - 0.0003061 43.0
SHD3_k127_2214757_0 Pfam:DUF2029 - - - 0.000000000000000000000000000000000000000396 157.0
SHD3_k127_2214757_1 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000005217 148.0
SHD3_k127_2214757_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000007033 109.0
SHD3_k127_2214757_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000001322 92.0
SHD3_k127_2215658_0 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004827 254.0
SHD3_k127_2215658_1 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000001313 156.0
SHD3_k127_2215658_2 Protein of unknown function (DUF971) - - - 0.000000000000000000001076 104.0
SHD3_k127_2222268_0 xanthine dehydrogenase activity - - - 9.412e-198 640.0
SHD3_k127_2222268_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 561.0
SHD3_k127_2222268_10 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000001282 202.0
SHD3_k127_2222268_11 BioY family K03523 - - 0.000000000000000000000000000000000000000000000000329 183.0
SHD3_k127_2222268_12 EAL domain-containing protein - - - 0.0000000000000000000000000000000000000000000008772 192.0
SHD3_k127_2222268_13 Sporulation and spore germination - - - 0.000000000000000000000000000000000000000000007279 176.0
SHD3_k127_2222268_14 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000002797 172.0
SHD3_k127_2222268_15 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000004756 154.0
SHD3_k127_2222268_16 domain, Protein - - - 0.000000000000000000000000000000000001787 156.0
SHD3_k127_2222268_17 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000007278 130.0
SHD3_k127_2222268_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000008632 146.0
SHD3_k127_2222268_19 aminopeptidase N - - - 0.0000000000000000000000000000003111 142.0
SHD3_k127_2222268_2 Nucleotidyl transferase K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 478.0
SHD3_k127_2222268_20 Peptidase family M23 K21471 - - 0.000000000000000000001084 109.0
SHD3_k127_2222268_21 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000363 75.0
SHD3_k127_2222268_22 Tetratricopeptide repeat - - - 0.0000000000009179 76.0
SHD3_k127_2222268_23 protein with SCP PR1 domains - - - 0.000000000002148 78.0
SHD3_k127_2222268_24 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000004905 70.0
SHD3_k127_2222268_25 Type IV leader peptidase family - - - 0.000002665 57.0
SHD3_k127_2222268_26 - - - - 0.000006878 56.0
SHD3_k127_2222268_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 447.0
SHD3_k127_2222268_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 398.0
SHD3_k127_2222268_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 297.0
SHD3_k127_2222268_6 His Kinase A (phosphoacceptor) domain K07654 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002205 268.0
SHD3_k127_2222268_7 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007747 251.0
SHD3_k127_2222268_8 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000006083 224.0
SHD3_k127_2222268_9 TRANSCRIPTIONal - - - 0.000000000000000000000000000000000000000000000000000172 204.0
SHD3_k127_2239774_0 PFAM isocitrate isopropylmalate dehydrogenase K00030,K07246 - 1.1.1.41,1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 482.0
SHD3_k127_2239774_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009361,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0042709,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 324.0
SHD3_k127_2239774_2 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000001423 224.0
SHD3_k127_2239774_3 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000000002069 113.0
SHD3_k127_2239774_4 succinate dehydrogenase activity K00242,K00246 - - 0.00000000004706 71.0
SHD3_k127_2240628_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 530.0
SHD3_k127_2240628_1 Inosine-uridine preferring nucleoside hydrolase K01239,K01250,K10213 - 3.2.2.1,3.2.2.8 0.00000000000000000000000000000009427 129.0
SHD3_k127_2253255_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 2.721e-207 658.0
SHD3_k127_2253255_1 Transcriptional regulator K22293 - - 0.000000000000000000000000000000000000000000000000000000000003188 214.0
SHD3_k127_2257342_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 339.0
SHD3_k127_2257342_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000003715 193.0
SHD3_k127_2257342_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000006818 106.0
SHD3_k127_2257342_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000008092 112.0
SHD3_k127_2257342_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0001659 47.0
SHD3_k127_2265923_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 395.0
SHD3_k127_2265923_1 PFAM Nucleotidyl transferase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000001545 184.0
SHD3_k127_2265923_2 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000313 147.0
SHD3_k127_2265923_3 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000001116 134.0
SHD3_k127_2265923_4 Sigma-70 region 2 K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000324 103.0
SHD3_k127_2265923_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000009623 99.0
SHD3_k127_2265923_6 SnoaL-like domain - - - 0.000000000000004172 83.0
SHD3_k127_2265923_7 PFAM zinc finger, SWIM domain protein - - - 0.00001748 50.0
SHD3_k127_2279903_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 447.0
SHD3_k127_2279903_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000002007 291.0
SHD3_k127_2279903_2 DegV family - - - 0.00000000000000000000000000000000000000000000000001414 192.0
SHD3_k127_2279903_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000001255 188.0
SHD3_k127_2296065_0 Domain of unknown function (DUF4445) - - - 1.363e-261 829.0
SHD3_k127_2296065_1 Trimethylamine methyltransferase (MTTB) - - - 2.004e-234 738.0
SHD3_k127_2296065_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 463.0
SHD3_k127_2296065_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 359.0
SHD3_k127_2296065_4 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000007923 235.0
SHD3_k127_2296065_5 Pterin binding enzyme K00548 - 2.1.1.13 0.000000000000000000000000000000008239 132.0
SHD3_k127_2296065_6 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000001674 111.0
SHD3_k127_2331262_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 424.0
SHD3_k127_2331262_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 344.0
SHD3_k127_2331262_10 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000001187 126.0
SHD3_k127_2331262_11 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000003547 126.0
SHD3_k127_2331262_12 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.00000000001355 68.0
SHD3_k127_2331262_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 375.0
SHD3_k127_2331262_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 294.0
SHD3_k127_2331262_4 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000007921 250.0
SHD3_k127_2331262_5 electron transfer flavoprotein, alpha subunit K03522 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000004314 211.0
SHD3_k127_2331262_6 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000007582 189.0
SHD3_k127_2331262_7 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000001272 173.0
SHD3_k127_2331262_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000007967 162.0
SHD3_k127_2331262_9 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000368 145.0
SHD3_k127_2392918_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 353.0
SHD3_k127_2392918_1 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003587 242.0
SHD3_k127_2392918_2 transcriptional regulator - - - 0.000000000000000000000000000000000000007978 154.0
SHD3_k127_2392918_3 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000005589 142.0
SHD3_k127_2392918_4 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000053 124.0
SHD3_k127_2392918_5 Virulence factor - - - 0.0000000000000003239 85.0
SHD3_k127_246340_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 432.0
SHD3_k127_246340_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 412.0
SHD3_k127_246340_2 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000000000000005518 199.0
SHD3_k127_246340_3 Phage integrase family - - - 0.00000000000000000000000000000000000000002334 164.0
SHD3_k127_246340_4 Secreted repeat of unknown function - - - 0.000000000000000000000000006671 120.0
SHD3_k127_246340_5 Polysaccharide deacetylase - - - 0.000000000000000000000007148 115.0
SHD3_k127_246340_6 Diguanylate cyclase K20956,K21021 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032153,GO:0032879,GO:0033554,GO:0036460,GO:0040012,GO:0040013,GO:0042802,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0051271,GO:0051716,GO:0052621,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146 2.7.7.65 0.000000000000000000003079 108.0
SHD3_k127_246340_7 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000002485 71.0
SHD3_k127_246340_8 PFAM PilT protein domain protein - - - 0.00000001941 61.0
SHD3_k127_251003_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 558.0
SHD3_k127_251003_1 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 492.0
SHD3_k127_251003_10 Memo-like protein K06990 - - 0.00000000000000000000000000000001889 146.0
SHD3_k127_251003_11 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000003709 141.0
SHD3_k127_251003_12 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000001825 120.0
SHD3_k127_251003_13 YCII-related domain - - - 0.0000000000000000000000000001944 121.0
SHD3_k127_251003_14 SnoaL-like domain - - - 0.0000000000000002069 93.0
SHD3_k127_251003_15 Protein conserved in bacteria - - - 0.00000000004749 64.0
SHD3_k127_251003_2 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 488.0
SHD3_k127_251003_3 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 366.0
SHD3_k127_251003_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 297.0
SHD3_k127_251003_5 phospholipase C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004856 279.0
SHD3_k127_251003_6 cyclic nucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000005423 213.0
SHD3_k127_251003_7 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000009392 211.0
SHD3_k127_251003_8 PFAM Rieske 2Fe-2S K16937 - 1.8.5.2 0.00000000000000000000000000000000000000000000000006259 193.0
SHD3_k127_251003_9 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 0.000000000000000000000000000000000000000000000009194 176.0
SHD3_k127_2526083_0 Cell cycle protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002775 278.0
SHD3_k127_2526083_1 PFAM Forkhead-associated protein - - - 0.000000000000000000000007913 110.0
SHD3_k127_2526083_2 PFAM Forkhead-associated protein - - - 0.0000000000000000005258 92.0
SHD3_k127_2541446_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.378e-206 660.0
SHD3_k127_2541446_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 589.0
SHD3_k127_2541446_10 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000001705 160.0
SHD3_k127_2541446_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000001128 102.0
SHD3_k127_2541446_12 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.00000000000005817 85.0
SHD3_k127_2541446_13 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000002565 67.0
SHD3_k127_2541446_14 Belongs to the UPF0102 family K07460 - - 0.0000000106 61.0
SHD3_k127_2541446_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 360.0
SHD3_k127_2541446_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 337.0
SHD3_k127_2541446_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 313.0
SHD3_k127_2541446_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 299.0
SHD3_k127_2541446_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 257.0
SHD3_k127_2541446_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000023 238.0
SHD3_k127_2541446_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000002183 202.0
SHD3_k127_2541446_9 zinc metalloprotease K04771,K11749,K16922 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 0.000000000000000000000000000000000000000000001201 179.0
SHD3_k127_2547271_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 450.0
SHD3_k127_2547271_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 435.0
SHD3_k127_2547271_10 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000006738 197.0
SHD3_k127_2547271_11 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000001789 134.0
SHD3_k127_2547271_12 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0008150,GO:0040007 1.2.1.70 0.000000000000000000000000000008189 133.0
SHD3_k127_2547271_13 recombinase activity K07450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000001443 108.0
SHD3_k127_2547271_2 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 367.0
SHD3_k127_2547271_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 353.0
SHD3_k127_2547271_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 352.0
SHD3_k127_2547271_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 335.0
SHD3_k127_2547271_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003937 291.0
SHD3_k127_2547271_7 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000156 222.0
SHD3_k127_2547271_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000006549 216.0
SHD3_k127_2547271_9 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000005748 206.0
SHD3_k127_2583546_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 497.0
SHD3_k127_2583546_1 PFAM AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000001448 237.0
SHD3_k127_2629706_0 ABC transporter, transmembrane region K06147 - - 1.482e-265 839.0
SHD3_k127_2629706_1 ABC transporter, transmembrane region K06147 - - 1.266e-216 690.0
SHD3_k127_2629706_2 Sugar-specific transcriptional regulator TrmB - - - 0.0000000002229 68.0
SHD3_k127_2629706_3 Phosphotransferase enzyme family - - - 0.0001668 44.0
SHD3_k127_2643020_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 481.0
SHD3_k127_2643020_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 443.0
SHD3_k127_2643020_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 353.0
SHD3_k127_2643020_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 304.0
SHD3_k127_2643020_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000003376 275.0
SHD3_k127_2643020_5 Activator of hsp90 atpase 1 family protein - - - 0.0000000003746 68.0
SHD3_k127_2649993_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1145.0
SHD3_k127_2649993_1 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.865e-231 743.0
SHD3_k127_2649993_10 PFAM Enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001892 285.0
SHD3_k127_2649993_11 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007339 276.0
SHD3_k127_2649993_12 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000005137 280.0
SHD3_k127_2649993_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003338 269.0
SHD3_k127_2649993_14 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002287 256.0
SHD3_k127_2649993_15 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000006015 218.0
SHD3_k127_2649993_16 Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000000000000000000005329 198.0
SHD3_k127_2649993_17 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000005582 196.0
SHD3_k127_2649993_18 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000004018 199.0
SHD3_k127_2649993_19 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000002348 190.0
SHD3_k127_2649993_2 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 588.0
SHD3_k127_2649993_20 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000001283 174.0
SHD3_k127_2649993_21 Iron-sulfur cluster assembly protein K02612 - - 0.0000000000000000000000000000000000000000000168 171.0
SHD3_k127_2649993_22 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000156 162.0
SHD3_k127_2649993_23 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000252 160.0
SHD3_k127_2649993_24 PFAM flavin reductase domain protein, FMN-binding K16048 - - 0.0000000000000000000000000000000003521 137.0
SHD3_k127_2649993_25 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000005405 141.0
SHD3_k127_2649993_26 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000002268 132.0
SHD3_k127_2649993_27 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000009989 113.0
SHD3_k127_2649993_28 Sulfurtransferase TusA - - - 0.00000000000000000000000001365 111.0
SHD3_k127_2649993_29 Alpha beta hydrolase - - - 0.0000000000000000000000002017 122.0
SHD3_k127_2649993_3 Belongs to the thiolase family K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 540.0
SHD3_k127_2649993_30 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.00000000000000000000005739 107.0
SHD3_k127_2649993_31 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000001156 106.0
SHD3_k127_2649993_32 PFAM DsrE DsrF-like family - - - 0.000000000000000000007292 102.0
SHD3_k127_2649993_34 phenylacetate catabolic process K02610 - - 0.0000000000000004667 91.0
SHD3_k127_2649993_35 - - - - 0.000000000000000572 90.0
SHD3_k127_2649993_36 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000007725 91.0
SHD3_k127_2649993_37 Transcriptional regulator - - - 0.0000000000001139 76.0
SHD3_k127_2649993_38 Diguanylate cyclase - - - 0.0000001697 60.0
SHD3_k127_2649993_39 EthD domain - - - 0.0000002369 57.0
SHD3_k127_2649993_4 TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 430.0
SHD3_k127_2649993_40 - - - - 0.0000003041 61.0
SHD3_k127_2649993_41 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000001485 52.0
SHD3_k127_2649993_42 META domain - - - 0.00002427 56.0
SHD3_k127_2649993_43 DsrE/DsrF/DrsH-like family - - - 0.000042 52.0
SHD3_k127_2649993_44 peptidyl-tyrosine sulfation - - - 0.0007621 52.0
SHD3_k127_2649993_5 iron assimilation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 358.0
SHD3_k127_2649993_6 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 352.0
SHD3_k127_2649993_7 PFAM Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 339.0
SHD3_k127_2649993_8 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 323.0
SHD3_k127_2649993_9 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 306.0
SHD3_k127_2654738_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 3.225e-246 792.0
SHD3_k127_2654738_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 563.0
SHD3_k127_2654738_10 Ribonuclease K07058 - - 0.00007125 55.0
SHD3_k127_2654738_2 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 472.0
SHD3_k127_2654738_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000001922 274.0
SHD3_k127_2654738_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004405 264.0
SHD3_k127_2654738_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004447 276.0
SHD3_k127_2654738_6 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004823 261.0
SHD3_k127_2654738_7 TIGRFAM competence damage-inducible protein CinA N-terminal domain K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000003283 246.0
SHD3_k127_2654738_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000005696 125.0
SHD3_k127_2654738_9 protein conserved in bacteria - - - 0.00000000002342 68.0
SHD3_k127_2664405_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 2306.0
SHD3_k127_2664405_1 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000000000000007164 227.0
SHD3_k127_2664405_2 heme binding K19720 - - 0.0000000000007849 75.0
SHD3_k127_270462_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.587e-262 851.0
SHD3_k127_270462_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 379.0
SHD3_k127_270462_10 FR47-like protein - - - 0.000000000000000000000000003928 124.0
SHD3_k127_270462_11 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001418 83.0
SHD3_k127_270462_12 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000004016 87.0
SHD3_k127_270462_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 359.0
SHD3_k127_270462_3 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 367.0
SHD3_k127_270462_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 318.0
SHD3_k127_270462_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 310.0
SHD3_k127_270462_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000007579 225.0
SHD3_k127_270462_7 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000003213 185.0
SHD3_k127_270462_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000008671 162.0
SHD3_k127_270462_9 Yqey-like protein K09117 - - 0.00000000000000000000000000002451 123.0
SHD3_k127_2730261_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 502.0
SHD3_k127_2730261_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 353.0
SHD3_k127_2730261_10 Ribosomal protein L34 K02914 - - 0.00000000001712 65.0
SHD3_k127_2730261_11 protein serine/threonine phosphatase activity - - - 0.00000000003644 77.0
SHD3_k127_2730261_12 Chloramphenicol phosphotransferase-like protein K18554 - - 0.0001273 45.0
SHD3_k127_2730261_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000008169 235.0
SHD3_k127_2730261_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001556 226.0
SHD3_k127_2730261_4 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000001408 210.0
SHD3_k127_2730261_5 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000004758 145.0
SHD3_k127_2730261_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000003565 142.0
SHD3_k127_2730261_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000002304 139.0
SHD3_k127_2730261_8 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000000002372 135.0
SHD3_k127_2730261_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000001988 78.0
SHD3_k127_2750852_0 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005785 239.0
SHD3_k127_2750852_1 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000002383 244.0
SHD3_k127_2750852_2 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000000000000000000001772 231.0
SHD3_k127_2802675_0 Evidence 2b Function of strongly homologous gene K02282 - - 0.00000000000000000000000003567 121.0
SHD3_k127_2802675_1 Pfam Secreted repeat of - - - 0.000000000000000000003551 100.0
SHD3_k127_2816484_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 511.0
SHD3_k127_2816484_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 331.0
SHD3_k127_2816484_10 - - - - 0.000004655 54.0
SHD3_k127_2816484_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 317.0
SHD3_k127_2816484_3 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000009831 211.0
SHD3_k127_2816484_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000002814 209.0
SHD3_k127_2816484_5 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000286 190.0
SHD3_k127_2816484_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000002282 193.0
SHD3_k127_2816484_7 - - - - 0.0000000000000000000000000001029 119.0
SHD3_k127_2816484_8 May be required for sporulation K09762 - - 0.0000000000003552 81.0
SHD3_k127_2816484_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000003827 66.0
SHD3_k127_2864802_0 DEAD DEAH box helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 499.0
SHD3_k127_2864802_1 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 441.0
SHD3_k127_2864802_2 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008307 402.0
SHD3_k127_2864802_3 Pfam:DUF2029 - - - 0.0000000000000000000000000000000000000001263 161.0
SHD3_k127_2864802_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000001231 119.0
SHD3_k127_2864802_5 Cold shock K03704 - - 0.00000000001523 70.0
SHD3_k127_2876529_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 580.0
SHD3_k127_2876529_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 476.0
SHD3_k127_2876529_10 Belongs to the RNA methyltransferase TrmD family K00554,K01770 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000007159 253.0
SHD3_k127_2876529_11 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000009211 252.0
SHD3_k127_2876529_12 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000001178 227.0
SHD3_k127_2876529_13 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000002348 217.0
SHD3_k127_2876529_14 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000001747 194.0
SHD3_k127_2876529_15 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000007517 177.0
SHD3_k127_2876529_16 Ribonuclease III family K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000001239 177.0
SHD3_k127_2876529_17 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000004874 162.0
SHD3_k127_2876529_18 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000003417 166.0
SHD3_k127_2876529_19 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000005935 145.0
SHD3_k127_2876529_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 463.0
SHD3_k127_2876529_20 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000002956 146.0
SHD3_k127_2876529_21 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000002256 115.0
SHD3_k127_2876529_22 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000002606 108.0
SHD3_k127_2876529_23 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000002991 116.0
SHD3_k127_2876529_24 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000003391 103.0
SHD3_k127_2876529_25 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000001802 105.0
SHD3_k127_2876529_26 Belongs to the UPF0109 family K06960 - - 0.000000000000000000005824 94.0
SHD3_k127_2876529_27 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000006983 95.0
SHD3_k127_2876529_28 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000002352 98.0
SHD3_k127_2876529_29 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000103 79.0
SHD3_k127_2876529_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 461.0
SHD3_k127_2876529_30 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000002123 83.0
SHD3_k127_2876529_31 Belongs to the UPF0102 family K07460 - - 0.000000001185 64.0
SHD3_k127_2876529_32 Ribosomal L28 family K02902 - - 0.0000001731 55.0
SHD3_k127_2876529_33 - - - - 0.0000003284 63.0
SHD3_k127_2876529_34 Protein conserved in bacteria - - - 0.0004564 50.0
SHD3_k127_2876529_4 PFAM Dak phosphatase K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 346.0
SHD3_k127_2876529_5 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 335.0
SHD3_k127_2876529_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 304.0
SHD3_k127_2876529_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002631 287.0
SHD3_k127_2876529_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000139 273.0
SHD3_k127_2876529_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001768 281.0
SHD3_k127_2890537_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 340.0
SHD3_k127_2890537_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 351.0
SHD3_k127_2890537_2 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 329.0
SHD3_k127_2890537_3 COG0076 Glutamate decarboxylase and related PLP-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000005906 246.0
SHD3_k127_2890537_4 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000005108 248.0
SHD3_k127_2890537_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000004145 211.0
SHD3_k127_2890537_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000002765 181.0
SHD3_k127_2890537_7 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000001583 168.0
SHD3_k127_2890537_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000004013 82.0
SHD3_k127_2890537_9 belongs to the sigma-70 factor family, ECF subfamily - - - 0.00000000006526 71.0
SHD3_k127_2899350_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 4.305e-249 779.0
SHD3_k127_2899350_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 589.0
SHD3_k127_2899350_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 336.0
SHD3_k127_2899350_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 326.0
SHD3_k127_2899350_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 297.0
SHD3_k127_2899350_5 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002251 219.0
SHD3_k127_2899350_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000002324 195.0
SHD3_k127_2899350_7 EamA-like transporter family - - - 0.000000000000000000000000000002483 133.0
SHD3_k127_2899350_8 Lysin motif - - - 0.0000000000000000000000000000739 132.0
SHD3_k127_296045_0 FeS assembly protein SufB K09014 - - 2.27e-210 663.0
SHD3_k127_296045_1 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 1.739e-196 630.0
SHD3_k127_296045_10 Uncharacterized protein family (UPF0051) K07033,K09015 - - 0.0000000000000000000000000000000000000000246 175.0
SHD3_k127_296045_11 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000009042 170.0
SHD3_k127_296045_12 Ornithine cyclodeaminase/mu-crystallin family - - - 0.00000000000000000000000000000000000006692 158.0
SHD3_k127_296045_13 Acetyltransferase (GNAT) domain K03824,K09964 - - 0.000000000000000000000000000000001468 138.0
SHD3_k127_296045_14 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000008118 143.0
SHD3_k127_296045_15 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000009991 139.0
SHD3_k127_296045_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000003868 83.0
SHD3_k127_296045_17 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.00000000001332 71.0
SHD3_k127_296045_18 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000001446 74.0
SHD3_k127_296045_2 Cysteine synthase K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 494.0
SHD3_k127_296045_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 438.0
SHD3_k127_296045_4 Cys/Met metabolism PLP-dependent enzyme K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 396.0
SHD3_k127_296045_5 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 318.0
SHD3_k127_296045_6 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 311.0
SHD3_k127_296045_7 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 304.0
SHD3_k127_296045_8 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001294 248.0
SHD3_k127_296045_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000003581 188.0
SHD3_k127_2965200_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 477.0
SHD3_k127_2965200_1 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 442.0
SHD3_k127_2965200_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 425.0
SHD3_k127_2965200_3 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 398.0
SHD3_k127_2965200_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 408.0
SHD3_k127_2965200_5 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000006759 188.0
SHD3_k127_2965200_6 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000000002662 175.0
SHD3_k127_2965200_7 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000008359 146.0
SHD3_k127_2965200_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000212 143.0
SHD3_k127_2965200_9 - - - - 0.00000000002576 74.0
SHD3_k127_2986761_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 475.0
SHD3_k127_2986761_1 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 450.0
SHD3_k127_2986761_2 amine dehydrogenase activity K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003144 269.0
SHD3_k127_2986761_3 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000001109 228.0
SHD3_k127_2986761_4 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000039 199.0
SHD3_k127_2986761_6 helix_turn_helix, mercury resistance - - - 0.0000000000000004137 85.0
SHD3_k127_2986761_7 cellulase activity - - - 0.0000003026 51.0
SHD3_k127_2986761_8 F420H(2)-dependent quinone reductase - - - 0.00002442 53.0
SHD3_k127_2990941_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000188 289.0
SHD3_k127_2990941_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000002832 127.0
SHD3_k127_2990941_2 PilT protein domain protein - - - 0.000000000000000000000000001069 117.0
SHD3_k127_2990941_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000001158 99.0
SHD3_k127_2990941_4 Domain of unknown function (DU1801) - - - 0.0000000000000000000009711 100.0
SHD3_k127_2990941_5 infection protein K07052 - - 0.000001761 53.0
SHD3_k127_2994171_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 614.0
SHD3_k127_2994171_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 440.0
SHD3_k127_2994171_10 domain protein K03709 - - 0.0000000000000000000000000000008648 131.0
SHD3_k127_2994171_11 Endonuclease/Exonuclease/phosphatase family K18764 - 3.1.13.4 0.000000000000000000000000009553 119.0
SHD3_k127_2994171_12 lactoylglutathione lyase activity - - - 0.00000000000000000000003038 104.0
SHD3_k127_2994171_13 response regulator - - - 0.0000000000000000002748 99.0
SHD3_k127_2994171_14 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000008597 101.0
SHD3_k127_2994171_15 phosphohistidine phosphatase, SixA K08296 - - 0.000000000353 71.0
SHD3_k127_2994171_17 molecular chaperone - - - 0.00000007603 65.0
SHD3_k127_2994171_18 Plays a role in the regulation of phosphate uptake K02039 - - 0.000007517 48.0
SHD3_k127_2994171_19 - - - - 0.0008038 46.0
SHD3_k127_2994171_2 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 350.0
SHD3_k127_2994171_3 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 316.0
SHD3_k127_2994171_4 Homocysteine S-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003085 284.0
SHD3_k127_2994171_5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001287 280.0
SHD3_k127_2994171_6 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000001483 208.0
SHD3_k127_2994171_7 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000004362 207.0
SHD3_k127_2994171_8 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000007001 157.0
SHD3_k127_3087742_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 354.0
SHD3_k127_3087742_1 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 296.0
SHD3_k127_3087742_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000002002 241.0
SHD3_k127_3087742_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000001674 165.0
SHD3_k127_3087742_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000008915 167.0
SHD3_k127_3087742_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000006798 138.0
SHD3_k127_3087742_6 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000001866 93.0
SHD3_k127_3142424_0 short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 335.0
SHD3_k127_3142424_1 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000005665 164.0
SHD3_k127_3142424_2 molybdopterin K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.000000000000000000000284 102.0
SHD3_k127_3142424_3 Protein of unknown function (DUF1461) - - - 0.00000000000000602 85.0
SHD3_k127_3142424_4 Domain of unknown function (DUF4332) - - - 0.0003034 50.0
SHD3_k127_3263005_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 376.0
SHD3_k127_3263005_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 352.0
SHD3_k127_3263005_2 PFAM Metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000165 275.0
SHD3_k127_3263005_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000001093 186.0
SHD3_k127_3263005_4 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000004774 181.0
SHD3_k127_3263005_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000003913 164.0
SHD3_k127_3263005_6 - - - - 0.000000000000000000000000006233 117.0
SHD3_k127_3263005_7 Glyoxalase-like domain - - - 0.0000000000000004262 83.0
SHD3_k127_3263005_8 F420H(2)-dependent quinone reductase - - - 0.000000004842 61.0
SHD3_k127_3281945_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000005638 261.0
SHD3_k127_3281945_1 adenosine deaminase K01488,K02029,K21053 - 3.5.4.2,3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000007547 223.0
SHD3_k127_3281945_2 Belongs to the HAD-like hydrolase superfamily K01101 - 3.1.3.41 0.0000000000000000000000000000000000000000514 169.0
SHD3_k127_3281945_3 Alpha/beta hydrolase family - - - 0.000000000000000000797 90.0
SHD3_k127_3281945_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000588 68.0
SHD3_k127_3337311_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 566.0
SHD3_k127_3337311_1 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 479.0
SHD3_k127_3337311_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 455.0
SHD3_k127_3337311_3 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 388.0
SHD3_k127_3337311_4 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 309.0
SHD3_k127_3337311_5 belongs to the urease gamma subunit family K14048 - 3.5.1.5 0.0000000000000000000000000000000000000000000001707 178.0
SHD3_k127_3337311_6 Putative single-stranded nucleic acids-binding domain K06346 - - 0.00000000000000000000000257 118.0
SHD3_k127_3337311_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000001676 97.0
SHD3_k127_3337311_8 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.000000004046 69.0
SHD3_k127_3365748_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.556e-208 684.0
SHD3_k127_3365748_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 455.0
SHD3_k127_3365748_2 SAICAR synthetase K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 334.0
SHD3_k127_3365748_3 Phosphoribosylglycinamide synthetase, C domain K01945,K11788 GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000009747 263.0
SHD3_k127_3365748_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
SHD3_k127_3365748_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000002511 80.0
SHD3_k127_3432146_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 352.0
SHD3_k127_3432146_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000005302 242.0
SHD3_k127_3432146_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000001141 223.0
SHD3_k127_3432146_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000009858 196.0
SHD3_k127_3432146_4 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000001916 173.0
SHD3_k127_3432146_5 ATPase or kinase K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000008471 122.0
SHD3_k127_3432146_6 Glycoprotease family K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000000000002989 89.0
SHD3_k127_3432146_7 Carbohydrate kinase - - - 0.000000003086 70.0
SHD3_k127_3432146_8 - - - - 0.00002245 57.0
SHD3_k127_3432146_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.0008789 47.0
SHD3_k127_3439497_0 Belongs to the aldehyde dehydrogenase family K09472 - 1.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 600.0
SHD3_k127_3439497_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 492.0
SHD3_k127_3439497_10 InterPro IPR014922 - - - 0.0000000000000000000000000000000000000392 155.0
SHD3_k127_3439497_11 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000004435 162.0
SHD3_k127_3439497_12 Cell envelope-related transcriptional attenuator domain - - - 0.0000000000000000000000000000000000005973 161.0
SHD3_k127_3439497_13 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000002697 134.0
SHD3_k127_3439497_14 Helix-turn-helix domain K07729 - - 0.00000000000000000002173 92.0
SHD3_k127_3439497_15 May play a role in the intracellular transport of hydrophobic ligands - - - 0.000000000000000001123 93.0
SHD3_k127_3439497_16 RibD C-terminal domain - - - 0.00000000000002997 85.0
SHD3_k127_3439497_17 - - - - 0.00000000000008796 77.0
SHD3_k127_3439497_18 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 - - 0.00000000001076 70.0
SHD3_k127_3439497_19 - - - - 0.0000002297 59.0
SHD3_k127_3439497_2 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 390.0
SHD3_k127_3439497_20 Sigma-70 region 2 K03088 - - 0.000009006 55.0
SHD3_k127_3439497_3 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 384.0
SHD3_k127_3439497_4 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 347.0
SHD3_k127_3439497_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002018 244.0
SHD3_k127_3439497_6 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000006041 234.0
SHD3_k127_3439497_7 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000006048 210.0
SHD3_k127_3439497_8 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000000000000000143 209.0
SHD3_k127_3439497_9 Carboxylate--amine ligase - - - 0.0000000000000000000000000000000000000000003711 168.0
SHD3_k127_3578767_0 PFAM Helicase conserved C-terminal domain K06877 - - 2.388e-256 813.0
SHD3_k127_3578767_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 585.0
SHD3_k127_3578767_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 351.0
SHD3_k127_3578767_3 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000001325 248.0
SHD3_k127_3578767_4 Exonuclease K07502 - - 0.00000000000000000000000000000000000000001644 173.0
SHD3_k127_3578767_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000005918 107.0
SHD3_k127_3578767_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852,K00874 - 2.7.1.15,2.7.1.4,2.7.1.45 0.000000000007799 76.0
SHD3_k127_3593315_0 trimethylamine methyltransferase K14083 - 2.1.1.250 5.39e-214 675.0
SHD3_k127_3593315_1 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 590.0
SHD3_k127_3593315_10 ArsC family - - - 0.00000000000000000000000000000006919 128.0
SHD3_k127_3593315_11 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000001521 128.0
SHD3_k127_3593315_12 Secreted repeat of unknown function - - - 0.00000000000000000000273 106.0
SHD3_k127_3593315_13 Domain of unknown function (DUF4349) - - - 0.0000000000006369 82.0
SHD3_k127_3593315_14 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.0001969 52.0
SHD3_k127_3593315_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 378.0
SHD3_k127_3593315_3 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 356.0
SHD3_k127_3593315_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 332.0
SHD3_k127_3593315_5 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001478 262.0
SHD3_k127_3593315_6 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000002793 197.0
SHD3_k127_3593315_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000003397 164.0
SHD3_k127_3593315_8 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000001506 135.0
SHD3_k127_3593315_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000001767 136.0
SHD3_k127_3634717_0 Evidence 5 No homology to any previously reported sequences - - - 4.955e-270 856.0
SHD3_k127_3634717_1 alcohol dehydrogenase K00008,K08322 - 1.1.1.14,1.1.1.380 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 476.0
SHD3_k127_3634717_2 cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 387.0
SHD3_k127_3634717_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000002432 192.0
SHD3_k127_3634717_5 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000005373 174.0
SHD3_k127_3655161_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.96e-244 792.0
SHD3_k127_3655161_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.015e-194 621.0
SHD3_k127_3655161_10 Belongs to the carbohydrate kinase PfkB family - - - 0.00000000000000000000004611 117.0
SHD3_k127_3655161_11 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000954 81.0
SHD3_k127_3655161_2 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 448.0
SHD3_k127_3655161_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 386.0
SHD3_k127_3655161_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 347.0
SHD3_k127_3655161_5 Pseudouridine-metabolizing bifunctional protein K16329,K16330 GO:0001522,GO:0003674,GO:0003824,GO:0004730,GO:0006139,GO:0006213,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009116,GO:0009451,GO:0009987,GO:0016070,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050225,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.1.83,4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000009018 248.0
SHD3_k127_3655161_6 galactose-6-phosphate isomerase activity K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000002923 182.0
SHD3_k127_3655161_7 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000002163 156.0
SHD3_k127_3655161_8 Major facilitator Superfamily K08223 - - 0.00000000000000000000000000000000007355 145.0
SHD3_k127_3655161_9 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000005478 130.0
SHD3_k127_3663840_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 421.0
SHD3_k127_3663840_1 Protein of unknown function (DUF1706) - - - 0.00000000000000000000000001943 115.0
SHD3_k127_3663840_2 Protein of unknown function (DUF4242) - - - 0.000001027 55.0
SHD3_k127_379556_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 4.392e-277 875.0
SHD3_k127_379556_1 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 444.0
SHD3_k127_379556_2 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 339.0
SHD3_k127_379556_3 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000000000000000000000000000005071 213.0
SHD3_k127_379556_4 PFAM Inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000007251 211.0
SHD3_k127_379556_5 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.00000000000000000000000000000000000000000001747 165.0
SHD3_k127_379556_6 - - - - 0.0000000000000000000000000000001944 139.0
SHD3_k127_379556_7 RDD family - - - 0.00002005 54.0
SHD3_k127_3850720_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 455.0
SHD3_k127_3850720_1 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000002859 161.0
SHD3_k127_3850720_2 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000000000000001644 113.0
SHD3_k127_3850720_3 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.00000000000006769 73.0
SHD3_k127_3867770_0 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000005775 201.0
SHD3_k127_3867770_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000545 155.0
SHD3_k127_3867770_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region K03641 - - 0.0000000000009298 81.0
SHD3_k127_3867770_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system - - - 0.00000000005157 74.0
SHD3_k127_3867770_4 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00005114 50.0
SHD3_k127_3868609_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 509.0
SHD3_k127_3868609_1 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 488.0
SHD3_k127_3868609_2 ATPases associated with a variety of cellular activities K10112,K10195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 408.0
SHD3_k127_3868609_3 ATPases associated with a variety of cellular activities K16785,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 342.0
SHD3_k127_3868609_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001627 242.0
SHD3_k127_3868609_5 hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000001184 242.0
SHD3_k127_3868609_6 ABC-type cobalt transport system, permease component K16925 - - 0.0000000000000000000000000000000000000003605 158.0
SHD3_k127_3868609_7 cobalt transport K16785 - - 0.000000000000000000000000000004619 132.0
SHD3_k127_3868609_8 Ion transport protein K10716 - - 0.0000000002407 64.0
SHD3_k127_3877197_0 Flavin containing amine oxidoreductase - - - 6.798e-232 731.0
SHD3_k127_3877197_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 524.0
SHD3_k127_3877197_10 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000004817 216.0
SHD3_k127_3877197_11 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000003884 213.0
SHD3_k127_3877197_12 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000001792 190.0
SHD3_k127_3877197_13 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000006944 133.0
SHD3_k127_3877197_14 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.00000000000000000000000000003463 134.0
SHD3_k127_3877197_15 Glycosyltransferase family 87 - - - 0.000000000000000000000000002868 126.0
SHD3_k127_3877197_16 Sigma-70 region 2 K03088 - - 0.00000000000000000000000008203 115.0
SHD3_k127_3877197_17 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000004032 87.0
SHD3_k127_3877197_18 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000005171 66.0
SHD3_k127_3877197_19 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000009953 61.0
SHD3_k127_3877197_2 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 431.0
SHD3_k127_3877197_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 402.0
SHD3_k127_3877197_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 385.0
SHD3_k127_3877197_5 Tryptophanyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 336.0
SHD3_k127_3877197_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 308.0
SHD3_k127_3877197_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 308.0
SHD3_k127_3877197_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004195 267.0
SHD3_k127_3877197_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000003773 248.0
SHD3_k127_3881220_0 response regulator receiver K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000001991 222.0
SHD3_k127_3881220_1 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000001804 198.0
SHD3_k127_3881220_2 Histidine kinase K10681 - 2.7.13.3 0.0000000000000000000000000000000000000000000000004779 197.0
SHD3_k127_3881220_3 ATP dependent DNA ligase domain protein - - - 0.0000000000000000000000000000002968 130.0
SHD3_k127_3881220_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000004757 130.0
SHD3_k127_3881220_5 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000002145 96.0
SHD3_k127_3881220_6 Universal stress protein family - - - 0.000000000003967 73.0
SHD3_k127_3885101_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.919e-264 827.0
SHD3_k127_3885101_1 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 2.183e-225 711.0
SHD3_k127_3885101_10 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005037 289.0
SHD3_k127_3885101_11 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000008656 270.0
SHD3_k127_3885101_12 - - - - 0.00000000000000000000000000000000000000000000000000009743 206.0
SHD3_k127_3885101_13 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000002257 190.0
SHD3_k127_3885101_14 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000123 181.0
SHD3_k127_3885101_15 Zn peptidase - - - 0.00000000000000000000000000000000000000000000001429 187.0
SHD3_k127_3885101_16 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000003047 191.0
SHD3_k127_3885101_17 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000001012 156.0
SHD3_k127_3885101_18 TIGRFAM histidinol phosphate phosphatase HisJ family K04486 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 0.00000000000000000000000000000000007034 145.0
SHD3_k127_3885101_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000004037 137.0
SHD3_k127_3885101_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 498.0
SHD3_k127_3885101_20 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000004245 130.0
SHD3_k127_3885101_21 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000003548 114.0
SHD3_k127_3885101_22 PFAM glycosyl transferase family 39 K00728 - 2.4.1.109 0.0000000000000000003635 101.0
SHD3_k127_3885101_23 Formiminotransferase-cyclodeaminase - - - 0.00000000000000009724 90.0
SHD3_k127_3885101_24 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000007292 79.0
SHD3_k127_3885101_25 Dodecin K09165 - - 0.000000002131 61.0
SHD3_k127_3885101_26 Protein of unknown function (DUF1232) - - - 0.00001985 54.0
SHD3_k127_3885101_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 479.0
SHD3_k127_3885101_4 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 481.0
SHD3_k127_3885101_5 TIGRFAM Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 441.0
SHD3_k127_3885101_6 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 389.0
SHD3_k127_3885101_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 362.0
SHD3_k127_3885101_8 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 332.0
SHD3_k127_3885101_9 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 308.0
SHD3_k127_3989942_0 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000005676 183.0
SHD3_k127_3989942_1 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000003189 182.0
SHD3_k127_3989942_2 Cytochrome C assembly protein - - - 0.000000000000000000000000005552 115.0
SHD3_k127_3991648_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 346.0
SHD3_k127_3991648_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 334.0
SHD3_k127_3991648_10 Protein of unknown function (DUF1290) - - - 0.00000000000000000000000006554 114.0
SHD3_k127_3991648_11 Cell division protein FtsQ K03589 - - 0.0000006963 61.0
SHD3_k127_3991648_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 303.0
SHD3_k127_3991648_3 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 312.0
SHD3_k127_3991648_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000261 278.0
SHD3_k127_3991648_5 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000003246 273.0
SHD3_k127_3991648_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000002222 234.0
SHD3_k127_3991648_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000001693 218.0
SHD3_k127_3991648_8 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000004432 220.0
SHD3_k127_3991648_9 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000007753 138.0
SHD3_k127_4054542_0 Uridine phosphorylase K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000003773 245.0
SHD3_k127_4054542_1 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000001208 103.0
SHD3_k127_4054542_2 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.00000000000000006735 96.0
SHD3_k127_4054542_3 - - - - 0.000000000000782 74.0
SHD3_k127_4136592_0 epimerase dehydratase K01710,K08678,K21211 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 460.0
SHD3_k127_4136592_1 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits K21210 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 355.0
SHD3_k127_4136592_2 GDP-mannose 4,6 dehydratase K21214 - - 0.000000000000000000000000000000000000000000000003395 186.0
SHD3_k127_4136592_3 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000001583 119.0
SHD3_k127_4136592_4 O-Antigen ligase - - - 0.00000001794 67.0
SHD3_k127_4136592_5 Glycosyl transferase 4-like - - - 0.000005742 55.0
SHD3_k127_4136592_6 Glycosyl transferase 4-like - - - 0.0001627 53.0
SHD3_k127_4144858_0 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015208,GO:0015851,GO:0015854,GO:0016020,GO:0022857,GO:0035344,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098657,GO:0098710,GO:0098739,GO:1903716,GO:1904823 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 418.0
SHD3_k127_4144858_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 317.0
SHD3_k127_4144858_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 310.0
SHD3_k127_4144858_3 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 308.0
SHD3_k127_4144858_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 305.0
SHD3_k127_4144858_5 DRTGG domain K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000167 252.0
SHD3_k127_4144858_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000009412 194.0
SHD3_k127_4144858_7 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000006879 189.0
SHD3_k127_4144858_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000001461 196.0
SHD3_k127_419127_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 347.0
SHD3_k127_419127_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000137 173.0
SHD3_k127_4196248_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.259e-267 852.0
SHD3_k127_4196248_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 514.0
SHD3_k127_4196248_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 349.0
SHD3_k127_4218700_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 8.877e-197 618.0
SHD3_k127_4218700_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 410.0
SHD3_k127_4218700_2 Exporter of polyketide antibiotics K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 373.0
SHD3_k127_4218700_3 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 349.0
SHD3_k127_4218700_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000003185 190.0
SHD3_k127_4218700_5 integral membrane protein - - - 0.000000000000000000000000000000004367 139.0
SHD3_k127_4218700_6 EamA-like transporter family - - - 0.0000957 46.0
SHD3_k127_4228252_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009198 559.0
SHD3_k127_4228252_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000002094 146.0
SHD3_k127_4228252_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000002413 124.0
SHD3_k127_4258360_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 2.488e-264 830.0
SHD3_k127_4258360_1 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 555.0
SHD3_k127_4258360_10 sequence-specific DNA binding K00567,K13529,K15051 - 2.1.1.63,3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000003422 241.0
SHD3_k127_4258360_11 conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001339 247.0
SHD3_k127_4258360_12 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000004315 247.0
SHD3_k127_4258360_13 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000003912 240.0
SHD3_k127_4258360_14 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001283 236.0
SHD3_k127_4258360_15 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000006875 228.0
SHD3_k127_4258360_16 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000119 203.0
SHD3_k127_4258360_17 UbiA prenyltransferase family K02548 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.00000000000000000000000000000000000000000000000005148 201.0
SHD3_k127_4258360_18 Cobalamin B12-binding K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000003367 184.0
SHD3_k127_4258360_19 Nitroreductase family - - - 0.00000000000000000000000000000000001409 141.0
SHD3_k127_4258360_2 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 375.0
SHD3_k127_4258360_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000006639 144.0
SHD3_k127_4258360_21 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.000000000000000000000000000000001806 143.0
SHD3_k127_4258360_22 Zincin-like metallopeptidase - - - 0.000000000000000000000000000004871 124.0
SHD3_k127_4258360_23 Thioredoxin-like K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000009784 122.0
SHD3_k127_4258360_24 BAAT Acyl-CoA thioester hydrolase - - - 0.00000000000000000000000001253 123.0
SHD3_k127_4258360_25 Serine aminopeptidase, S33 - - - 0.00000000000000000000005078 109.0
SHD3_k127_4258360_26 CAAX protease self-immunity K07052 - - 0.0000000000000000000001 114.0
SHD3_k127_4258360_27 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000001937 89.0
SHD3_k127_4258360_28 Acyl-CoA dehydrogenase, middle domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.00000000000000001533 93.0
SHD3_k127_4258360_29 Transcriptional regulator, arsR family - - - 0.00000000000000001761 85.0
SHD3_k127_4258360_3 Dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 376.0
SHD3_k127_4258360_30 PFAM regulatory protein, ArsR - - - 0.00000000000002492 81.0
SHD3_k127_4258360_31 choline dehydrogenase activity - - - 0.0000000000002362 80.0
SHD3_k127_4258360_32 Luciferase-like monooxygenase - - - 0.000000000001517 81.0
SHD3_k127_4258360_33 Helix-turn-helix domain - - - 0.000000001775 61.0
SHD3_k127_4258360_34 DnaJ molecular chaperone homology domain - - - 0.00000001611 64.0
SHD3_k127_4258360_35 Copper binding proteins, plastocyanin/azurin family - - - 0.00000001682 67.0
SHD3_k127_4258360_36 - - - - 0.0000000265 61.0
SHD3_k127_4258360_37 Protein of unknown function (DUF1706) - - - 0.0001 51.0
SHD3_k127_4258360_38 FR47-like protein - - - 0.000119 55.0
SHD3_k127_4258360_4 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 330.0
SHD3_k127_4258360_5 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 327.0
SHD3_k127_4258360_6 COGs COG3367 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 316.0
SHD3_k127_4258360_7 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001042 279.0
SHD3_k127_4258360_8 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000002644 263.0
SHD3_k127_4258360_9 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003169 268.0
SHD3_k127_4274303_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 582.0
SHD3_k127_4274303_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 422.0
SHD3_k127_4274303_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000007705 186.0
SHD3_k127_4274752_0 R3H domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 565.0
SHD3_k127_4274752_1 metallopeptidase activity K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 496.0
SHD3_k127_4274752_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000001326 195.0
SHD3_k127_4274752_11 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000003771 191.0
SHD3_k127_4274752_12 SnoaL-like polyketide cyclase K15945 - - 0.000000000000000000000000000000000000000001357 178.0
SHD3_k127_4274752_13 Cyclic-di-AMP receptor - - - 0.00000000000000000000000000002089 124.0
SHD3_k127_4274752_14 nUDIX hydrolase K01515,K03574,K08310 - 3.6.1.13,3.6.1.55,3.6.1.67 0.0000000000000002659 85.0
SHD3_k127_4274752_15 diguanylate cyclase - - - 0.00000000000006062 83.0
SHD3_k127_4274752_16 MarR family - - - 0.000000000005559 76.0
SHD3_k127_4274752_17 - - - - 0.0000000008143 70.0
SHD3_k127_4274752_18 F420H(2)-dependent quinone reductase - - - 0.0005026 49.0
SHD3_k127_4274752_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 454.0
SHD3_k127_4274752_3 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 447.0
SHD3_k127_4274752_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 448.0
SHD3_k127_4274752_5 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 400.0
SHD3_k127_4274752_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 329.0
SHD3_k127_4274752_7 peptidase U62, modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004259 267.0
SHD3_k127_4274752_8 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003839 246.0
SHD3_k127_4274752_9 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000001398 223.0
SHD3_k127_430454_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 559.0
SHD3_k127_430454_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 469.0
SHD3_k127_430454_2 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 384.0
SHD3_k127_430454_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001991 286.0
SHD3_k127_430454_4 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000001822 173.0
SHD3_k127_430454_5 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000003912 156.0
SHD3_k127_430454_6 Modulates RecA activity K03565 - - 0.000000000000001441 84.0
SHD3_k127_4324747_0 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 1.276e-254 805.0
SHD3_k127_4324747_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 9.373e-244 781.0
SHD3_k127_4324747_10 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000561 255.0
SHD3_k127_4324747_11 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006104,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000004195 215.0
SHD3_k127_4324747_12 Belongs to the HpcH HpaI aldolase family K01630,K02510,K12660 - 4.1.2.20,4.1.2.52,4.1.2.53 0.000000000000000000000000000000000000000000000000000000003175 214.0
SHD3_k127_4324747_13 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000004468 188.0
SHD3_k127_4324747_14 Peptidase s1 and s6 chymotrypsin hap - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.000000000000000000000000000000000000000000002098 180.0
SHD3_k127_4324747_15 Major facilitator superfamily - - - 0.000000000000000000000000000000004773 147.0
SHD3_k127_4324747_16 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000008541 113.0
SHD3_k127_4324747_17 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000001728 126.0
SHD3_k127_4324747_18 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000005965 117.0
SHD3_k127_4324747_19 Sigma-70 region 2 K03088 - - 0.0000000000000000000003861 105.0
SHD3_k127_4324747_2 Adenylate K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 581.0
SHD3_k127_4324747_20 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000002284 95.0
SHD3_k127_4324747_21 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000008549 86.0
SHD3_k127_4324747_22 PFAM CBS domain containing protein - - - 0.000000000000007198 83.0
SHD3_k127_4324747_23 PFAM blue (type 1) copper domain protein - - - 0.000000000001691 76.0
SHD3_k127_4324747_24 amine dehydrogenase activity - - - 0.0000000003318 73.0
SHD3_k127_4324747_25 cAMP-dependent protein kinase regulator activity K04739,K07359,K15117,K15348 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006839,GO:0008150,GO:0008272,GO:0015698,GO:0015711,GO:0015729,GO:0015740,GO:0015849,GO:0016020,GO:0016021,GO:0019866,GO:0022857,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0072348 2.7.11.17 0.00000002241 67.0
SHD3_k127_4324747_26 transcriptional regulator - - - 0.000005033 59.0
SHD3_k127_4324747_3 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 529.0
SHD3_k127_4324747_4 PFAM homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 493.0
SHD3_k127_4324747_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 472.0
SHD3_k127_4324747_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 477.0
SHD3_k127_4324747_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 389.0
SHD3_k127_4324747_8 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 335.0
SHD3_k127_4324747_9 Creatinase/Prolidase N-terminal domain K01271,K01274 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 322.0
SHD3_k127_4345116_0 MreB/Mbl protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 437.0
SHD3_k127_4345116_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 282.0
SHD3_k127_4345116_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000003311 227.0
SHD3_k127_4345116_3 Double zinc ribbon - - - 0.0000000000000000000001134 106.0
SHD3_k127_4345116_4 CAAX protease self-immunity K07052 - - 0.00000002231 66.0
SHD3_k127_4345271_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.859e-203 645.0
SHD3_k127_4345271_1 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 314.0
SHD3_k127_4345271_10 Binds directly to 16S ribosomal RNA K02968 - - 0.0000006544 61.0
SHD3_k127_4345271_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002245 257.0
SHD3_k127_4345271_3 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000004838 255.0
SHD3_k127_4345271_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000001119 225.0
SHD3_k127_4345271_5 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000002356 183.0
SHD3_k127_4345271_6 DinB family - - - 0.000000000000000000000000000000000000002406 153.0
SHD3_k127_4345271_7 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000002939 132.0
SHD3_k127_4345271_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000004884 140.0
SHD3_k127_4345271_9 CAAX protease self-immunity K07052 - - 0.000000536 60.0
SHD3_k127_4353410_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1065.0
SHD3_k127_4353410_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.044e-265 839.0
SHD3_k127_4353410_10 COG0147 Anthranilate para-aminobenzoate synthases component I K01665,K13950 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 335.0
SHD3_k127_4353410_11 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 355.0
SHD3_k127_4353410_12 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 316.0
SHD3_k127_4353410_13 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002 307.0
SHD3_k127_4353410_14 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000985 290.0
SHD3_k127_4353410_15 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002259 276.0
SHD3_k127_4353410_16 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004059 288.0
SHD3_k127_4353410_17 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002919 275.0
SHD3_k127_4353410_18 transport system permease K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003797 268.0
SHD3_k127_4353410_19 N-acetylglucosaminylinositol deacetylase activity K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000004343 251.0
SHD3_k127_4353410_2 Lysine-2,3-aminomutase K01843 - 5.4.3.2 5.333e-218 702.0
SHD3_k127_4353410_20 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005063 273.0
SHD3_k127_4353410_21 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002158 249.0
SHD3_k127_4353410_22 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005006 250.0
SHD3_k127_4353410_23 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000009198 232.0
SHD3_k127_4353410_24 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000008385 234.0
SHD3_k127_4353410_25 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000001644 220.0
SHD3_k127_4353410_26 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000001348 223.0
SHD3_k127_4353410_27 Heat shock protein DnaJ domain protein K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000309 218.0
SHD3_k127_4353410_28 TrkA-C domain K03499 - - 0.000000000000000000000000000000000000000000000000000000009448 205.0
SHD3_k127_4353410_29 protein flavinylation K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000002233 196.0
SHD3_k127_4353410_3 MMPL family K06994 - - 9.889e-195 648.0
SHD3_k127_4353410_30 Amino-transferase class IV K00826,K02619 - 2.6.1.42,4.1.3.38 0.00000000000000000000000000000000000000000000003911 181.0
SHD3_k127_4353410_31 Belongs to the BI1 family K06890,K19416 - - 0.00000000000000000000000000000000000000000001453 171.0
SHD3_k127_4353410_32 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000252 161.0
SHD3_k127_4353410_33 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000003576 149.0
SHD3_k127_4353410_34 NYN domain - - - 0.0000000000000000000000000000000000004099 160.0
SHD3_k127_4353410_35 Cytidylate kinase-like family K00760 - 2.4.2.8 0.0000000000000000000000000000000002241 141.0
SHD3_k127_4353410_36 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000001277 138.0
SHD3_k127_4353410_37 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000001874 133.0
SHD3_k127_4353410_38 Ferric reductase like transmembrane component K17247 - - 0.000000000000000000000000000003283 132.0
SHD3_k127_4353410_39 domain protein K03499,K10716 - - 0.000000000000000000000000000009213 130.0
SHD3_k127_4353410_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 587.0
SHD3_k127_4353410_40 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000001152 132.0
SHD3_k127_4353410_41 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000004862 117.0
SHD3_k127_4353410_42 PFAM peptidyl-prolyl cis-trans isomerase cyclophilin type K03768 - 5.2.1.8 0.000000000000000000000000409 120.0
SHD3_k127_4353410_43 AMP binding - - - 0.00000000000000000000008923 105.0
SHD3_k127_4353410_44 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000009171 97.0
SHD3_k127_4353410_45 NUDIX domain - - - 0.0000000000000000000303 106.0
SHD3_k127_4353410_46 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000002294 96.0
SHD3_k127_4353410_47 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000002814 93.0
SHD3_k127_4353410_48 DSBA-like thioredoxin domain - - - 0.0000000000000000002906 101.0
SHD3_k127_4353410_49 Transcriptional regulator - - - 0.000000000000000005012 92.0
SHD3_k127_4353410_5 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 501.0
SHD3_k127_4353410_51 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000003285 90.0
SHD3_k127_4353410_52 Pfam:DUF59 - - - 0.00000000000004254 78.0
SHD3_k127_4353410_53 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.000000000006312 75.0
SHD3_k127_4353410_54 PFAM Vitamin K epoxide reductase - - - 0.000000000392 69.0
SHD3_k127_4353410_57 ACT domain - - - 0.000000001039 66.0
SHD3_k127_4353410_58 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.0000001421 63.0
SHD3_k127_4353410_59 Phospholipase_D-nuclease N-terminal - - - 0.0000002191 54.0
SHD3_k127_4353410_6 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 401.0
SHD3_k127_4353410_60 Protein of unknown function (DUF433) - - - 0.0002175 52.0
SHD3_k127_4353410_7 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 393.0
SHD3_k127_4353410_8 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 351.0
SHD3_k127_4353410_9 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 338.0
SHD3_k127_4356702_0 ABC transporter, ATP-binding protein K02028,K02029 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 338.0
SHD3_k127_4356702_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008076 288.0
SHD3_k127_4356702_2 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
SHD3_k127_4356702_3 ABC transporter substrate-binding protein K02030,K02424,K17073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001134 271.0
SHD3_k127_4356702_4 WYL domain K13572 - - 0.000000000000000000000000000000000000000000000000000000000000000001504 242.0
SHD3_k127_4356702_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000004338 231.0
SHD3_k127_4356702_6 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000005408 149.0
SHD3_k127_4356702_7 diguanylate cyclase - - - 0.0000000000000000000000000000000001347 149.0
SHD3_k127_4356702_8 Peptidase M23 K21471 - - 0.0000000000000008029 89.0
SHD3_k127_4373565_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 442.0
SHD3_k127_4373565_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 432.0
SHD3_k127_4373565_2 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000003735 100.0
SHD3_k127_4373565_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000582 102.0
SHD3_k127_4373565_4 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000005182 106.0
SHD3_k127_4373565_5 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.000000000000000008109 96.0
SHD3_k127_4377572_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 453.0
SHD3_k127_4377572_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 447.0
SHD3_k127_4377572_2 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002082 289.0
SHD3_k127_4377572_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002592 251.0
SHD3_k127_4377572_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002531 256.0
SHD3_k127_4377572_5 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000003101 209.0
SHD3_k127_4377572_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.00000000000000000000000000000000000000000000000000000003221 220.0
SHD3_k127_4377572_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000007891 124.0
SHD3_k127_4388556_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 543.0
SHD3_k127_4388556_1 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 441.0
SHD3_k127_4388556_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 355.0
SHD3_k127_4388556_3 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration K05573 - 1.6.5.3 0.0000000000000000000000000000000002189 141.0
SHD3_k127_4388556_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000004308 95.0
SHD3_k127_4388556_5 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K05578 - 1.6.5.3 0.0000000000000000431 91.0
SHD3_k127_4395053_0 ATPase associated with various cellular activities, AAA_5 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 424.0
SHD3_k127_4395053_1 Cell division protein FtsI penicillin-binding protein K05364 - - 0.000000000000000000000000000000000000000000000000000000000000000001958 248.0
SHD3_k127_4395053_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000007642 226.0
SHD3_k127_4395053_3 Belongs to the SEDS family K03588 - - 0.000000000000000006038 85.0
SHD3_k127_4395053_4 Transglutaminase/protease-like homologues - - - 0.000001906 59.0
SHD3_k127_4427894_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 595.0
SHD3_k127_4427894_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 434.0
SHD3_k127_4427894_2 NAD binding domain of 6-phosphogluconate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 312.0
SHD3_k127_4427894_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 298.0
SHD3_k127_4427894_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 290.0
SHD3_k127_4427894_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000002708 119.0
SHD3_k127_4430470_0 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 515.0
SHD3_k127_4430470_1 PFAM galactose-1-phosphate uridyl transferase domain protein K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 399.0
SHD3_k127_4430470_2 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 305.0
SHD3_k127_4430470_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000001721 182.0
SHD3_k127_4431826_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 600.0
SHD3_k127_4431826_1 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000181 303.0
SHD3_k127_4431826_2 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000002891 160.0
SHD3_k127_4431826_3 Kdo2-lipid A biosynthetic process K02517,K22311 - 2.3.1.241,2.3.1.265 0.000000000000000000000000000001861 135.0
SHD3_k127_4431826_4 Major facilitator superfamily - - - 0.0000000000000000000001453 105.0
SHD3_k127_4431826_5 CDP-alcohol phosphatidyltransferase K00995,K00999 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 0.0000000000000000000003051 109.0
SHD3_k127_4431826_6 Bacterial lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.000000000004039 78.0
SHD3_k127_4431826_7 DNA-binding transcription factor activity K03892 - - 0.0000000006316 66.0
SHD3_k127_445591_0 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002421 278.0
SHD3_k127_445591_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000081 248.0
SHD3_k127_445591_2 Phosphoesterase (MutT - - - 0.00000002043 58.0
SHD3_k127_4462296_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 479.0
SHD3_k127_4462296_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 364.0
SHD3_k127_4462296_2 NADH dehydrogenase K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 310.0
SHD3_k127_4462296_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001025 292.0
SHD3_k127_4462296_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000003879 76.0
SHD3_k127_4486669_0 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 361.0
SHD3_k127_4486669_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 321.0
SHD3_k127_4486669_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000002764 216.0
SHD3_k127_4486669_3 transcriptional regulator K22491 - - 0.0000000000000000000000000000000000000000000000000000000002037 216.0
SHD3_k127_4486669_4 - - - - 0.0000000000000000005269 93.0
SHD3_k127_4486669_5 Domain of unknown function (DUF378) K09779 - - 0.0000000001234 66.0
SHD3_k127_4578884_0 Amidohydrolase family K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 583.0
SHD3_k127_4578884_1 Dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 552.0
SHD3_k127_4578884_2 catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation K17723 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 510.0
SHD3_k127_4578884_3 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 454.0
SHD3_k127_4578884_4 Belongs to the proline racemase family K01777 - 5.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 417.0
SHD3_k127_4578884_5 Glutamate synthase K17722 - 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 377.0
SHD3_k127_4578884_6 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000133 226.0
SHD3_k127_4578884_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000006872 229.0
SHD3_k127_4578884_8 domain, Protein - - - 0.000000000000000000000000000000000000000000000005401 196.0
SHD3_k127_4578884_9 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000005581 130.0
SHD3_k127_4597856_0 Kelch motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004806 284.0
SHD3_k127_4597856_1 Sigma-70 region 2 K03088 - - 0.000000000000000000002215 101.0
SHD3_k127_4632631_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 601.0
SHD3_k127_4632631_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 400.0
SHD3_k127_4632631_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000001642 225.0
SHD3_k127_4632631_11 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000001773 220.0
SHD3_k127_4632631_12 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000002769 206.0
SHD3_k127_4632631_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000004001 198.0
SHD3_k127_4632631_14 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.0000000000000000000000000000000000000000000000000000002893 210.0
SHD3_k127_4632631_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000001483 198.0
SHD3_k127_4632631_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000002234 190.0
SHD3_k127_4632631_17 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002332 192.0
SHD3_k127_4632631_18 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000005497 178.0
SHD3_k127_4632631_19 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000009719 166.0
SHD3_k127_4632631_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 408.0
SHD3_k127_4632631_20 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000006041 155.0
SHD3_k127_4632631_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000007365 157.0
SHD3_k127_4632631_22 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000003625 162.0
SHD3_k127_4632631_23 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001155 142.0
SHD3_k127_4632631_24 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000009809 143.0
SHD3_k127_4632631_25 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000001399 147.0
SHD3_k127_4632631_26 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000008063 128.0
SHD3_k127_4632631_27 PFAM ribosomal protein L17 K02879 - - 0.00000000000000000000000000000002704 128.0
SHD3_k127_4632631_28 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000007642 124.0
SHD3_k127_4632631_29 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000008021 113.0
SHD3_k127_4632631_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 371.0
SHD3_k127_4632631_30 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000001804 113.0
SHD3_k127_4632631_31 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000539 104.0
SHD3_k127_4632631_32 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000007794 104.0
SHD3_k127_4632631_33 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000008265 113.0
SHD3_k127_4632631_34 YbbR-like protein - - - 0.0000000000000000000000994 115.0
SHD3_k127_4632631_35 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000002404 94.0
SHD3_k127_4632631_36 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000001626 83.0
SHD3_k127_4632631_37 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001462 71.0
SHD3_k127_4632631_38 Ribosomal protein L30p/L7e K02907 - - 0.0000000000007462 70.0
SHD3_k127_4632631_39 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000003065 55.0
SHD3_k127_4632631_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 320.0
SHD3_k127_4632631_40 Transcriptional regulatory protein, C terminal - - - 0.0004406 51.0
SHD3_k127_4632631_5 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001716 286.0
SHD3_k127_4632631_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001766 262.0
SHD3_k127_4632631_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001115 265.0
SHD3_k127_4632631_8 Ribosomal protein S3, C-terminal domain K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002612 265.0
SHD3_k127_4632631_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000004876 236.0
SHD3_k127_4634497_0 Helix-hairpin-helix motif K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 638.0
SHD3_k127_4634497_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 531.0
SHD3_k127_4634497_2 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 339.0
SHD3_k127_4634497_3 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002152 282.0
SHD3_k127_4634497_4 MafB19-like deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000005219 216.0
SHD3_k127_4634497_5 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.0000000000000000000000000000000000000000000000000000006624 219.0
SHD3_k127_4634497_6 methyltransferase K15471 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000003859 153.0
SHD3_k127_4634497_7 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000003384 147.0
SHD3_k127_4634497_8 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000001127 108.0
SHD3_k127_4634497_9 impB/mucB/samB family K14161 - - 0.00000000002009 77.0
SHD3_k127_4653830_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 473.0
SHD3_k127_4653830_1 Rossmann-like domain - - - 0.00000000000000000000000003037 119.0
SHD3_k127_4653855_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 372.0
SHD3_k127_4653855_1 Uracil DNA glycosylase superfamily K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 303.0
SHD3_k127_4653855_2 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007116 269.0
SHD3_k127_4653855_3 deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000001471 212.0
SHD3_k127_4653855_4 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000003526 136.0
SHD3_k127_4653855_5 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000009311 125.0
SHD3_k127_46846_0 AAA domain - - - 3.175e-274 885.0
SHD3_k127_46846_1 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 6.977e-200 636.0
SHD3_k127_46846_10 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000007028 187.0
SHD3_k127_46846_11 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000004413 168.0
SHD3_k127_46846_12 - - - - 0.0000000000000000000000004645 109.0
SHD3_k127_46846_13 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000001649 112.0
SHD3_k127_46846_15 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000006468 64.0
SHD3_k127_46846_2 N-terminal domain of (some) glycogen debranching enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 542.0
SHD3_k127_46846_3 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 534.0
SHD3_k127_46846_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 518.0
SHD3_k127_46846_5 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 368.0
SHD3_k127_46846_6 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008677 254.0
SHD3_k127_46846_7 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000003395 225.0
SHD3_k127_46846_8 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000002242 230.0
SHD3_k127_46846_9 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000001761 211.0
SHD3_k127_4724480_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00823 - 2.6.1.19,4.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 537.0
SHD3_k127_4724480_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 526.0
SHD3_k127_4724480_2 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 380.0
SHD3_k127_4724480_3 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002139 284.0
SHD3_k127_4724480_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000008163 212.0
SHD3_k127_4724480_5 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.00000000000000000000000000000000001143 149.0
SHD3_k127_4724480_6 enoyl-[acyl-carrier-protein] reductase (NADH) activity K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.00000004277 65.0
SHD3_k127_4826521_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000009549 184.0
SHD3_k127_4826521_1 Transmembrane secretion effector - - - 0.0002986 49.0
SHD3_k127_4826992_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000001272 199.0
SHD3_k127_4826992_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000006594 158.0
SHD3_k127_4826992_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000006207 94.0
SHD3_k127_4826992_3 Glycosyltransferase family 87 K13671 - - 0.000001047 59.0
SHD3_k127_4826992_4 Glycosyltransferase family 87 - - - 0.000001385 60.0
SHD3_k127_4826992_5 Pfam:DUF2029 - - - 0.00001708 52.0
SHD3_k127_484641_0 Belongs to the malate synthase family K01638 - 2.3.3.9 1.982e-195 624.0
SHD3_k127_484641_1 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000004056 224.0
SHD3_k127_484641_2 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000000000007619 179.0
SHD3_k127_484641_3 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000127 80.0
SHD3_k127_484641_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000001563 77.0
SHD3_k127_484641_5 - - - - 0.0000000000001035 83.0
SHD3_k127_4875514_0 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.0000000000000000000000000007658 129.0
SHD3_k127_4875514_1 GTP binding - - - 0.0000000002312 72.0
SHD3_k127_48781_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.987e-209 662.0
SHD3_k127_48781_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 1.575e-199 644.0
SHD3_k127_48781_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004357 267.0
SHD3_k127_4885392_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 522.0
SHD3_k127_4885392_1 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 312.0
SHD3_k127_4885392_11 TPM domain K06872 - - 0.0000007343 63.0
SHD3_k127_4885392_12 DNAJ heat shock N-terminal domain-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.000001845 60.0
SHD3_k127_4885392_13 EamA-like transporter family - - - 0.00001982 56.0
SHD3_k127_4885392_2 PFAM Luciferase-like - - - 0.00000000000000000000000000000000000000000000006709 181.0
SHD3_k127_4885392_3 lysozyme - - - 0.000000000000000000000000000000001288 151.0
SHD3_k127_4885392_4 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000004777 141.0
SHD3_k127_4885392_5 FR47-like protein - - - 0.0000000000000000000000000000002113 128.0
SHD3_k127_4885392_6 cellulase activity - - - 0.00000000000000000000000000003574 137.0
SHD3_k127_4885392_8 pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000001433 99.0
SHD3_k127_4885392_9 Transglycosylase associated protein - - - 0.00000000008382 65.0
SHD3_k127_4897604_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 482.0
SHD3_k127_4897604_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000005264 188.0
SHD3_k127_4897604_2 DNA-templated transcription, initiation K03088 - - 0.000000005952 66.0
SHD3_k127_4905623_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 459.0
SHD3_k127_4905623_1 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 374.0
SHD3_k127_4905623_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000006066 116.0
SHD3_k127_5004516_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1078.0
SHD3_k127_5004516_1 DEAD/H associated K03724 - - 1.511e-236 758.0
SHD3_k127_5004516_2 Peptidase family S51 K13282 - 3.4.15.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000003926 264.0
SHD3_k127_5004516_3 Belongs to the FPG family K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000002015 220.0
SHD3_k127_5004516_4 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000003554 162.0
SHD3_k127_5009033_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.19e-222 706.0
SHD3_k127_5009033_1 FGGY family of carbohydrate kinases, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 617.0
SHD3_k127_5009033_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000005157 211.0
SHD3_k127_5009033_11 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000000000003156 199.0
SHD3_k127_5009033_12 MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000001799 150.0
SHD3_k127_5009033_13 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0000000000000000000000000000000000007796 155.0
SHD3_k127_5009033_14 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000001791 143.0
SHD3_k127_5009033_15 TOBE domain - - - 0.000000000000000000000000000000003868 133.0
SHD3_k127_5009033_16 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000006712 134.0
SHD3_k127_5009033_17 Cupin domain - - - 0.00000000000000000000000000692 114.0
SHD3_k127_5009033_18 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.0000000000000000000000003254 115.0
SHD3_k127_5009033_19 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000143 51.0
SHD3_k127_5009033_2 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 434.0
SHD3_k127_5009033_3 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 419.0
SHD3_k127_5009033_4 Acetylornithine deacetylase K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 312.0
SHD3_k127_5009033_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006658 279.0
SHD3_k127_5009033_6 ZIP Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003379 271.0
SHD3_k127_5009033_7 Phosphatidylinositol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000225 254.0
SHD3_k127_5009033_8 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000004427 237.0
SHD3_k127_5009033_9 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000004207 214.0
SHD3_k127_5012061_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 368.0
SHD3_k127_5012061_1 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001665 260.0
SHD3_k127_5012061_2 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000002523 251.0
SHD3_k127_5012061_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000003833 185.0
SHD3_k127_5012061_4 DUF218 domain - - - 0.00000000000000000000000000000000000002884 151.0
SHD3_k127_5012061_5 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.0000000000000000000000000000000000001328 154.0
SHD3_k127_5012061_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000001537 152.0
SHD3_k127_5012061_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000004887 113.0
SHD3_k127_5012105_0 Alpha amylase, catalytic domain - - - 2.841e-224 735.0
SHD3_k127_5012105_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 2.635e-196 637.0
SHD3_k127_5012105_10 PFAM amino acid-binding ACT domain protein - - - 0.000000000006294 72.0
SHD3_k127_5012105_11 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000007528 64.0
SHD3_k127_5012105_2 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 531.0
SHD3_k127_5012105_3 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 336.0
SHD3_k127_5012105_4 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 324.0
SHD3_k127_5012105_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002715 216.0
SHD3_k127_5012105_6 uridine kinase - - - 0.0000000000000000000000000000000003584 153.0
SHD3_k127_5012105_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000008818 128.0
SHD3_k127_5012105_8 Ferric reductase like transmembrane component - - - 0.00000000000000000000000004454 119.0
SHD3_k127_5012105_9 Serine aminopeptidase, S33 - - - 0.0000000000000000003382 102.0
SHD3_k127_5045230_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 575.0
SHD3_k127_5045230_1 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001156 260.0
SHD3_k127_5045230_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000006954 137.0
SHD3_k127_5057483_0 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 491.0
SHD3_k127_5057483_1 Belongs to the ABC transporter superfamily K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 460.0
SHD3_k127_5057483_2 Required for the activity of the bacterial periplasmic transport system of putrescine K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 421.0
SHD3_k127_5057483_3 Alanine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 313.0
SHD3_k127_5057483_4 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001169 288.0
SHD3_k127_5057483_5 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000006244 244.0
SHD3_k127_5057483_6 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.000000000000000000000000000000000000000000000001994 181.0
SHD3_k127_5057483_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05524 - - 0.000000000000000000000000003464 123.0
SHD3_k127_5057483_8 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000005082 93.0
SHD3_k127_5070874_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 601.0
SHD3_k127_5070874_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 576.0
SHD3_k127_5070874_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000001152 119.0
SHD3_k127_5070874_3 membrane protein (DUF2078) K08982 - - 0.000000004833 64.0
SHD3_k127_5078100_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 541.0
SHD3_k127_5078100_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 524.0
SHD3_k127_5078100_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 475.0
SHD3_k127_5078100_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001326 229.0
SHD3_k127_5125547_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 560.0
SHD3_k127_5125547_1 ABC transporter K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 462.0
SHD3_k127_5125547_2 Transport permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 301.0
SHD3_k127_5125547_3 Transport permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000003629 216.0
SHD3_k127_5133004_0 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 371.0
SHD3_k127_5133004_1 PAS fold domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 375.0
SHD3_k127_5133004_2 Mur ligase, middle domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 308.0
SHD3_k127_5133004_3 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000007958 210.0
SHD3_k127_5133004_4 PFAM CobB CobQ domain protein glutamine amidotransferase K07009 - - 0.00000000000000000000000000000000000000000000001743 188.0
SHD3_k127_5133004_5 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000001906 128.0
SHD3_k127_5133004_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000005228 129.0
SHD3_k127_5133004_7 Glycosyl hydrolases family 18 - - - 0.00000000000000006928 94.0
SHD3_k127_5133004_8 PFAM blue (type 1) copper domain protein - - - 0.0000000001874 69.0
SHD3_k127_5133004_9 Hemerythrin hhe cation binding - - - 0.00001142 55.0
SHD3_k127_5150848_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 451.0
SHD3_k127_5150848_1 Protein of unknown function (DUF2652) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 341.0
SHD3_k127_5150848_2 methylamine metabolic process K15977 - - 0.0000000000000000000000000000004436 129.0
SHD3_k127_518025_0 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 430.0
SHD3_k127_518025_1 Cytochrome b/b6/petB K03891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 331.0
SHD3_k127_518025_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000002285 222.0
SHD3_k127_518025_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000002305 177.0
SHD3_k127_518025_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000006719 154.0
SHD3_k127_518025_5 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.000000000000000000000000006303 120.0
SHD3_k127_518025_6 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000001251 91.0
SHD3_k127_518025_8 Domain of unknown function (DUF309) K09763 - - 0.000000107 61.0
SHD3_k127_518025_9 Kelch motif - - - 0.000004823 59.0
SHD3_k127_5183116_0 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 384.0
SHD3_k127_5183116_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 383.0
SHD3_k127_5183116_2 response regulator K07668,K07775 - - 0.00000000000000000000000000000000000000000000000000000000000000000002912 239.0
SHD3_k127_5183116_3 Dehydrogenase K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000006984 205.0
SHD3_k127_5183116_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000001715 202.0
SHD3_k127_5183116_5 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000001172 157.0
SHD3_k127_5183116_6 His Kinase A (phosphoacceptor) domain K07642 - 2.7.13.3 0.000000000000000000000000000002505 140.0
SHD3_k127_5183116_7 VWA domain containing CoxE-like protein K07161 - - 0.00000000003378 70.0
SHD3_k127_5183116_8 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000317 56.0
SHD3_k127_5222286_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000006423 162.0
SHD3_k127_5222286_1 Family of unknown function (DUF5317) - - - 0.0000000004863 72.0
SHD3_k127_5225062_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 4.941e-236 740.0
SHD3_k127_5225062_1 Beta-eliminating lyase K01667,K01668 - 4.1.99.1,4.1.99.2 2.854e-230 720.0
SHD3_k127_5225062_10 HlyD family secretion protein K02005,K13888 - - 0.0000000000000000000000000007343 129.0
SHD3_k127_5225062_11 Lytic transglycolase K03642 - - 0.000000000000000002326 92.0
SHD3_k127_5225062_12 positive regulation of type IV pilus biogenesis K07343 - - 0.000000000000000009827 96.0
SHD3_k127_5225062_13 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000003378 76.0
SHD3_k127_5225062_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 1.53e-225 715.0
SHD3_k127_5225062_3 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 422.0
SHD3_k127_5225062_4 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 370.0
SHD3_k127_5225062_5 MacB-like periplasmic core domain K02004,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 318.0
SHD3_k127_5225062_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 290.0
SHD3_k127_5225062_7 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000004452 247.0
SHD3_k127_5225062_8 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000002602 237.0
SHD3_k127_5225062_9 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000001147 176.0
SHD3_k127_5227525_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000001071 260.0
SHD3_k127_5227525_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000002547 167.0
SHD3_k127_5227525_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000004584 166.0
SHD3_k127_5246438_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 370.0
SHD3_k127_5246438_1 Isochorismatase family K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000002557 222.0
SHD3_k127_5246438_2 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000002421 145.0
SHD3_k127_5293746_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 426.0
SHD3_k127_5293746_1 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001754 269.0
SHD3_k127_5293746_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000001094 251.0
SHD3_k127_5293746_3 elongation factor Tu domain 2 protein K02355 - - 0.00000000000000000000000000000000000000000000000000001003 198.0
SHD3_k127_5293746_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000004313 185.0
SHD3_k127_5293746_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000001363 169.0
SHD3_k127_5293746_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000004636 134.0
SHD3_k127_5293746_7 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000000009748 66.0
SHD3_k127_5301988_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.359e-214 674.0
SHD3_k127_5301988_1 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 463.0
SHD3_k127_5301988_2 Participates in initiation and elongation during chromosome replication K02314,K02316,K17680 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000002725 249.0
SHD3_k127_5301988_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000003932 172.0
SHD3_k127_5301988_4 Prephenate dehydrogenase K00210,K00220,K04517 - 1.3.1.12,1.3.1.43 0.000000000000000000000000000000199 137.0
SHD3_k127_5301988_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000004686 119.0
SHD3_k127_5301988_6 - - - - 0.0000000000000000000001524 108.0
SHD3_k127_5347178_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.188e-195 632.0
SHD3_k127_5347178_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 331.0
SHD3_k127_5347178_10 AI-2E family transporter - - - 0.0000000000000000000000000002139 128.0
SHD3_k127_5347178_11 PFAM membrane-flanked domain - - - 0.00000000000000000000000003427 124.0
SHD3_k127_5347178_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000002364 105.0
SHD3_k127_5347178_13 trisaccharide binding K03556 - - 0.0000000000002499 79.0
SHD3_k127_5347178_14 mRNA catabolic process - - - 0.00000000007932 74.0
SHD3_k127_5347178_15 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657,K18941 - - 0.000000008634 58.0
SHD3_k127_5347178_2 tyrosine recombinase K04763 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005137 263.0
SHD3_k127_5347178_3 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002354 247.0
SHD3_k127_5347178_4 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000461 245.0
SHD3_k127_5347178_5 - - - - 0.000000000000000000000000000000000000000000003097 179.0
SHD3_k127_5347178_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000001903 175.0
SHD3_k127_5347178_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000002196 160.0
SHD3_k127_5347178_8 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000006607 154.0
SHD3_k127_5347178_9 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000002246 138.0
SHD3_k127_5364763_0 RsgA GTPase K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 320.0
SHD3_k127_5364763_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001567 290.0
SHD3_k127_5364763_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 284.0
SHD3_k127_5364763_3 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000003921 213.0
SHD3_k127_5364763_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000002743 160.0
SHD3_k127_5364763_5 - - - - 0.000000000008294 65.0
SHD3_k127_5364763_6 carbon monoxide dehydrogenase K09386 - - 0.0000000002169 68.0
SHD3_k127_5382265_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 568.0
SHD3_k127_5382265_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 500.0
SHD3_k127_5382265_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000193 273.0
SHD3_k127_5382265_3 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.00000000000000000000000000000000000000000000000000000000000000003655 233.0
SHD3_k127_5382265_4 response regulator, receiver K02483,K07667 - - 0.0000000000000000000000000000000000000000000000000000000000006638 221.0
SHD3_k127_541750_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.086e-270 850.0
SHD3_k127_541750_1 Transcriptional regulator - - - 0.00007825 53.0
SHD3_k127_5440020_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 422.0
SHD3_k127_5440020_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 371.0
SHD3_k127_5440020_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 347.0
SHD3_k127_5440020_3 glycolate biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000002242 218.0
SHD3_k127_5440020_4 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000002812 142.0
SHD3_k127_5440020_5 sulfur carrier activity - - - 0.0000000000000000000001896 100.0
SHD3_k127_5474622_0 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000008049 71.0
SHD3_k127_5474622_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000001244 55.0
SHD3_k127_5474622_2 signal transduction histidine kinase - - - 0.0000005062 57.0
SHD3_k127_5474622_3 DNA integration - - - 0.0009869 44.0
SHD3_k127_553333_0 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002121 250.0
SHD3_k127_553333_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07777 - 2.7.13.3 0.00000000000000000000000000000000003296 149.0
SHD3_k127_553333_2 Histidine kinase K07777 - 2.7.13.3 0.000000000000000000000001145 118.0
SHD3_k127_553333_4 Flp/Fap pilin component K02651 - - 0.0001409 46.0
SHD3_k127_553333_5 Flp/Fap pilin component K02651 - - 0.0003617 44.0
SHD3_k127_5544262_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 569.0
SHD3_k127_5544262_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 537.0
SHD3_k127_5544262_2 Aminotransferase K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 494.0
SHD3_k127_5544262_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000002518 101.0
SHD3_k127_5544262_4 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.000009139 55.0
SHD3_k127_5547061_0 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000001657 217.0
SHD3_k127_5547061_1 PFAM Rhomboid family K19225 - 3.4.21.105 0.00000000001707 76.0
SHD3_k127_5549794_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 406.0
SHD3_k127_5549794_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 334.0
SHD3_k127_5549794_10 translation initiation factor activity K06996 - - 0.00000000000000000001061 96.0
SHD3_k127_5549794_11 Phosphate acyltransferases - - - 0.00000000000000007017 91.0
SHD3_k127_5549794_12 Phage shock protein C, PspC K03973 - - 0.00000000000004764 80.0
SHD3_k127_5549794_13 UbiA prenyltransferase family - - - 0.0000000000004495 80.0
SHD3_k127_5549794_14 - - - - 0.000002396 59.0
SHD3_k127_5549794_15 protein phosphatase 2C domain protein - - - 0.000005486 55.0
SHD3_k127_5549794_16 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0002758 45.0
SHD3_k127_5549794_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 295.0
SHD3_k127_5549794_3 N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001303 289.0
SHD3_k127_5549794_4 Sporulation initiation inhibitor protein Soj K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002173 247.0
SHD3_k127_5549794_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001473 245.0
SHD3_k127_5549794_6 - - - - 0.0000000000000000000000000000000000000000000000000000002032 199.0
SHD3_k127_5549794_7 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000006694 179.0
SHD3_k127_5549794_8 LysE type translocator - - - 0.000000000000000000000000000000000000000000000004048 180.0
SHD3_k127_5549794_9 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000001312 171.0
SHD3_k127_5557063_0 ECF sigma factor K03088 - - 0.00000000000000000000002901 108.0
SHD3_k127_5557063_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000001695 98.0
SHD3_k127_5557063_2 Superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.00000000000000000002389 92.0
SHD3_k127_5557063_3 Nickel-containing superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.0000000000000002453 83.0
SHD3_k127_5557063_4 membrane K08972 - - 0.00000000000008631 80.0
SHD3_k127_5557063_5 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000511 56.0
SHD3_k127_5557063_6 Glycosyl hydrolases family 18 - - - 0.00005778 55.0
SHD3_k127_5580842_0 Sigma-54 interaction domain K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 573.0
SHD3_k127_5580842_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 417.0
SHD3_k127_5580842_2 DALR_2 K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 405.0
SHD3_k127_5580842_3 SMART Nucleotide binding protein, PINc - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001452 287.0
SHD3_k127_5580842_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000001024 127.0
SHD3_k127_5599683_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006131 249.0
SHD3_k127_5599683_1 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000003424 196.0
SHD3_k127_5599683_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000001031 183.0
SHD3_k127_5599683_3 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000002441 146.0
SHD3_k127_5599683_4 Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.0000000000000000000000000000000000114 147.0
SHD3_k127_5599683_5 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.000000000000000000005454 103.0
SHD3_k127_5599683_6 Helix-turn-helix domain - - - 0.00001418 55.0
SHD3_k127_5608585_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 389.0
SHD3_k127_5608585_1 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000167 240.0
SHD3_k127_5608585_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000001032 72.0
SHD3_k127_5608585_3 Rieske-like [2Fe-2S] domain K05710 - - 0.0000000001456 68.0
SHD3_k127_5608585_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000004067 72.0
SHD3_k127_5608585_5 SIS domain K00820 - 2.6.1.16 0.00000006083 61.0
SHD3_k127_5696879_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 579.0
SHD3_k127_5696879_1 transcriptional regulator - - - 0.0000000000000000000000000007829 118.0
SHD3_k127_5696879_2 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000001138 72.0
SHD3_k127_597193_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 455.0
SHD3_k127_597193_1 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 378.0
SHD3_k127_597193_10 dna ligase K01971 - 6.5.1.1 0.000008194 56.0
SHD3_k127_597193_11 Cellulose synthase K20543 - - 0.0002615 48.0
SHD3_k127_597193_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 336.0
SHD3_k127_597193_3 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 329.0
SHD3_k127_597193_4 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000001176 273.0
SHD3_k127_597193_5 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000101 265.0
SHD3_k127_597193_6 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000004547 215.0
SHD3_k127_597193_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000004633 196.0
SHD3_k127_597193_8 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000003593 180.0
SHD3_k127_597193_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000001305 82.0
SHD3_k127_599401_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00821 - 2.6.1.11,2.6.1.17,4.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 468.0
SHD3_k127_599401_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004832 284.0
SHD3_k127_599401_10 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000004125 168.0
SHD3_k127_599401_11 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000001424 147.0
SHD3_k127_599401_12 Redoxin - - - 0.0000000000000000000000000000000001164 142.0
SHD3_k127_599401_13 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000133 134.0
SHD3_k127_599401_14 Cold shock K03704 - - 0.0000000001513 63.0
SHD3_k127_599401_15 electron transfer activity K05337 - - 0.0002431 53.0
SHD3_k127_599401_16 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0004571 53.0
SHD3_k127_599401_2 B3/4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006687 253.0
SHD3_k127_599401_3 PFAM Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000001032 226.0
SHD3_k127_599401_4 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000003675 219.0
SHD3_k127_599401_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000009765 217.0
SHD3_k127_599401_6 LysM domain - - - 0.0000000000000000000000000000000000000000000000000009786 190.0
SHD3_k127_599401_7 response regulator K02479 - - 0.000000000000000000000000000000000000000000000000001817 198.0
SHD3_k127_599401_8 pfam nudix - - - 0.00000000000000000000000000000000000000000000006798 176.0
SHD3_k127_599401_9 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000007813 176.0
SHD3_k127_610147_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 342.0
SHD3_k127_610147_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 310.0
SHD3_k127_610147_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999,K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001765 272.0
SHD3_k127_610147_3 Transcriptional regulator K22293 - - 0.000000000000000000000000000000000000000000000000000000000000000000007143 244.0
SHD3_k127_610147_4 DeoR C terminal sensor domain K02081 - - 0.000000000000000000000000000000000000000008112 164.0
SHD3_k127_610147_5 Cupin domain - - - 0.0000004229 57.0
SHD3_k127_610147_6 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00001164 54.0
SHD3_k127_610147_7 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K11381 - 1.2.4.4 0.0002252 51.0
SHD3_k127_612847_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 577.0
SHD3_k127_612847_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 457.0
SHD3_k127_612847_10 COG0419 ATPase involved in DNA repair - - - 0.0000004819 63.0
SHD3_k127_612847_11 F420H(2)-dependent quinone reductase - - - 0.000009476 56.0
SHD3_k127_612847_2 membrane - - - 0.000000000000000000000000000000000000000000000000000001687 204.0
SHD3_k127_612847_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000004707 169.0
SHD3_k127_612847_4 Selenocysteine-specific translation elongation factor K03833 - - 0.000000000000000000000000000000000627 149.0
SHD3_k127_612847_5 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000001615 131.0
SHD3_k127_612847_6 Probable zinc-ribbon domain - - - 0.0000000000000000000000000002596 123.0
SHD3_k127_612847_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000006409 83.0
SHD3_k127_612847_8 PFAM Metallophosphoesterase K01090 - 3.1.3.16 0.00000000000001914 76.0
SHD3_k127_612847_9 AAA domain - - - 0.0000000000002763 84.0
SHD3_k127_63040_0 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000004894 220.0
SHD3_k127_63040_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000002217 139.0
SHD3_k127_63040_3 PFAM Phosphoribosyltransferase K02242 - - 0.00000000000000000000000000002833 126.0
SHD3_k127_63040_4 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000008302 91.0
SHD3_k127_63040_5 PFAM type II secretion system protein K12511 - - 0.00000000000001114 75.0
SHD3_k127_63040_6 Glycosyltransferase family 87 K13671 - - 0.000000001322 70.0
SHD3_k127_63040_7 transcriptional regulator, XRE family - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0002943 51.0
SHD3_k127_652151_0 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000003688 151.0
SHD3_k127_652151_1 Ribonuclease H K03469 - 3.1.26.4 0.0000000000000000000000006014 113.0
SHD3_k127_652151_2 PFAM LysM domain - - - 0.0000000000001097 80.0
SHD3_k127_666288_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 1.228e-265 836.0
SHD3_k127_666288_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 513.0
SHD3_k127_666288_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000005585 208.0
SHD3_k127_666288_11 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000001646 155.0
SHD3_k127_666288_12 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000009611 129.0
SHD3_k127_666288_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000002325 117.0
SHD3_k127_666288_14 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000003803 117.0
SHD3_k127_666288_15 Binds the 23S rRNA K02909 - - 0.000000000000000000000001709 107.0
SHD3_k127_666288_16 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000005424 98.0
SHD3_k127_666288_17 thiolester hydrolase activity K03186 - 2.5.1.129 0.000000000000000001586 94.0
SHD3_k127_666288_18 ATP synthase F(0) sector subunit b K02109 - - 0.00000000000000004155 89.0
SHD3_k127_666288_19 Cysteine-rich CPCC - - - 0.000000000000003443 79.0
SHD3_k127_666288_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 354.0
SHD3_k127_666288_20 PFAM PKD domain containing protein - - - 0.00000000007692 74.0
SHD3_k127_666288_21 Dna alkylation repair - - - 0.00000003243 65.0
SHD3_k127_666288_22 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000003367 59.0
SHD3_k127_666288_23 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000005719 61.0
SHD3_k127_666288_24 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0001938 48.0
SHD3_k127_666288_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 337.0
SHD3_k127_666288_4 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 338.0
SHD3_k127_666288_5 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 306.0
SHD3_k127_666288_6 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000024 269.0
SHD3_k127_666288_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001944 261.0
SHD3_k127_666288_8 transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000002196 239.0
SHD3_k127_666288_9 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000008063 236.0
SHD3_k127_680520_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.108e-227 734.0
SHD3_k127_680520_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.331e-196 629.0
SHD3_k127_680520_10 Molecular chaperone - - - 0.0000000006297 71.0
SHD3_k127_680520_2 Belongs to the FtsK SpoIIIE SftA family K03466 GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 478.0
SHD3_k127_680520_3 Acetolactate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 389.0
SHD3_k127_680520_4 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000172 258.0
SHD3_k127_680520_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000002506 205.0
SHD3_k127_680520_6 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000005427 175.0
SHD3_k127_680520_7 Competence-damaged protein K03742,K03743 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.1.42 0.000000000000000000000000000000000003613 142.0
SHD3_k127_680520_8 SMART helix-turn-helix domain protein - - - 0.00000000000002205 86.0
SHD3_k127_680520_9 Ribosomal_S15 K02956 - - 0.000000000002719 67.0
SHD3_k127_687512_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 436.0
SHD3_k127_687512_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000001245 273.0
SHD3_k127_687512_10 - - - - 0.0001812 47.0
SHD3_k127_687512_11 Hep Hag repeat protein - - - 0.0002081 53.0
SHD3_k127_687512_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000016 261.0
SHD3_k127_687512_3 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000003952 241.0
SHD3_k127_687512_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000008624 215.0
SHD3_k127_687512_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000006845 188.0
SHD3_k127_687512_6 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.000000000000000000000000004866 117.0
SHD3_k127_687512_7 serine threonine protein kinase - - - 0.00000000000000000000001214 112.0
SHD3_k127_687512_8 Peptidase A4 family - - - 0.000000000000001056 89.0
SHD3_k127_687512_9 - - - - 0.00000006025 58.0
SHD3_k127_723162_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 8.504e-241 754.0
SHD3_k127_723162_1 Dihydropyrimidinase K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 612.0
SHD3_k127_723162_2 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 379.0
SHD3_k127_723162_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 317.0
SHD3_k127_72435_0 aconitate hydratase K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 7.598e-205 654.0
SHD3_k127_72435_1 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000002368 193.0
SHD3_k127_72435_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000001564 175.0
SHD3_k127_72435_3 nitrite reductase [NAD(P)H] activity K05710 - - 0.00000000000000000000002217 104.0
SHD3_k127_769858_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 454.0
SHD3_k127_769858_1 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 390.0
SHD3_k127_769858_10 - - - - 0.0003244 53.0
SHD3_k127_769858_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000001528 280.0
SHD3_k127_769858_3 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000005477 253.0
SHD3_k127_769858_4 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000004483 213.0
SHD3_k127_769858_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000006658 171.0
SHD3_k127_769858_6 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000003786 156.0
SHD3_k127_769858_7 Lipid A core-O-antigen ligase-like enyme - - - 0.00000000000001348 87.0
SHD3_k127_769858_8 PFAM Glycosyl transferase, group 1 K00786 - - 0.000000000004869 70.0
SHD3_k127_769858_9 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000004329 66.0
SHD3_k127_775433_0 ABC transporter transmembrane region K06147 - - 5.716e-246 785.0
SHD3_k127_775433_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 6.376e-201 671.0
SHD3_k127_775433_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000003779 146.0
SHD3_k127_775433_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000002146 109.0
SHD3_k127_775433_12 alcohol dehydrogenase K00008,K08322 - 1.1.1.14,1.1.1.380 0.00000000000000000000007202 98.0
SHD3_k127_775433_13 exo-alpha-(2->6)-sialidase activity - - - 0.0000000001142 74.0
SHD3_k127_775433_2 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 608.0
SHD3_k127_775433_3 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 473.0
SHD3_k127_775433_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 441.0
SHD3_k127_775433_5 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002587 286.0
SHD3_k127_775433_6 COG1226 Kef-type K transport systems K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006632 293.0
SHD3_k127_775433_7 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000003015 241.0
SHD3_k127_775433_8 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000478 214.0
SHD3_k127_775433_9 serine threonine protein kinase K03587,K08884,K12132 - 2.7.11.1,3.4.16.4 0.000000000000000000000000000000000000000000000000000000007734 214.0
SHD3_k127_80544_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 3.883e-321 1009.0
SHD3_k127_80544_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 606.0
SHD3_k127_80544_2 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 336.0
SHD3_k127_80544_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008524 247.0
SHD3_k127_80544_4 Nucleoside K01239 - 3.2.2.1 0.00000000000000000000000000000000000000000000006833 174.0
SHD3_k127_80544_5 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000001226 144.0
SHD3_k127_80544_6 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000004279 147.0
SHD3_k127_80544_7 Adenylate cyclase regulatory domain - - - 0.00000000000000000000000000000004092 141.0
SHD3_k127_829240_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 414.0
SHD3_k127_829240_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000004588 119.0
SHD3_k127_839547_0 PFAM Amidohydrolase 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 308.0
SHD3_k127_839547_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006748 275.0
SHD3_k127_839547_10 Bacterial protein of unknown function (DUF881) - - - 0.0000000000000000003727 99.0
SHD3_k127_839547_11 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000001583 84.0
SHD3_k127_839547_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000001367 236.0
SHD3_k127_839547_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000002117 220.0
SHD3_k127_839547_4 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000005845 203.0
SHD3_k127_839547_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000004056 185.0
SHD3_k127_839547_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000005411 169.0
SHD3_k127_839547_7 PFAM Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000001323 119.0
SHD3_k127_839547_8 Peptidase MA superfamily - - - 0.000000000000000000000000008468 127.0
SHD3_k127_839547_9 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000001928 91.0
SHD3_k127_844175_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 461.0
SHD3_k127_844175_1 PFAM alanine dehydrogenase PNT domain protein K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 421.0
SHD3_k127_844175_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 392.0
SHD3_k127_844175_3 Glycosyl transferase, family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000006586 243.0
SHD3_k127_844175_4 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000000000000000005515 204.0
SHD3_k127_844175_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000001487 185.0
SHD3_k127_844175_6 the transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000006725 153.0
SHD3_k127_844175_7 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000008406 141.0
SHD3_k127_844175_8 NADP transhydrogenase K00324 - 1.6.1.2 0.000000000000000000000000001095 128.0
SHD3_k127_91636_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003941 283.0
SHD3_k127_91636_1 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.0000000000000000000000000000000000000000000007027 184.0
SHD3_k127_91636_2 Major intrinsic protein K06188 - - 0.0000000000000000000000000000002082 134.0
SHD3_k127_91636_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000003949 109.0
SHD3_k127_91636_4 PFAM Class II Aldolase K01628 - 4.1.2.17 0.000000000000004839 84.0
SHD3_k127_91636_5 MscS Mechanosensitive ion channel - - - 0.00000000001069 72.0
SHD3_k127_922733_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 512.0
SHD3_k127_922733_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000001299 203.0
SHD3_k127_922733_2 VIT family - - - 0.0000000000000000000000000000000000000000000000007872 184.0
SHD3_k127_922733_3 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000000000001153 131.0
SHD3_k127_922733_4 transmembrane transporter activity - - - 0.000000000000000000000000003896 126.0
SHD3_k127_922733_5 cysteine - - - 0.0000000000000000000000001884 119.0
SHD3_k127_922733_6 GAF domain - - - 0.00000000000000000000001816 107.0
SHD3_k127_922733_7 Tautomerase enzyme - - - 0.00000000000000000003963 97.0
SHD3_k127_968284_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 372.0
SHD3_k127_968284_1 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 307.0
SHD3_k127_968284_2 Ion channel - - - 0.000000000000000000000000000000000000000000000000000001743 211.0
SHD3_k127_968284_3 cytochrome c biogenesis protein K07399 - - 0.00000000000000000000000000000000000000000000003766 188.0
SHD3_k127_968284_4 diguanylate cyclase - - - 0.000000000000000000000000000000000002371 153.0
SHD3_k127_968284_5 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000000005904 122.0
SHD3_k127_968284_6 helix_turn_helix ASNC type K03718 - - 0.000001045 50.0