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Overview

ID MAG03572
Name SRD2_bin.29
Sample SMP0089
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Steroidobacterales
Family Steroidobacteraceae
Genus 13-2-20CM-66-19
Species
Assembly information
Completeness (%) 86.87
Contamination (%) 0.53
GC content (%) 69.0
N50 (bp) 26,964
Genome size (bp) 3,210,038

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2869

Gene name Description KEGG GOs EC E-value Score Sequence
SRD2_k127_100966_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.479e-247 784.0
SRD2_k127_100966_1 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 7.738e-204 653.0
SRD2_k127_100966_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 559.0
SRD2_k127_100966_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 445.0
SRD2_k127_100966_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 440.0
SRD2_k127_100966_5 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 304.0
SRD2_k127_100966_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000002513 280.0
SRD2_k127_100966_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000001807 214.0
SRD2_k127_100966_8 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000003239 199.0
SRD2_k127_100966_9 Septum formation initiator K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301 - 0.000000000000000000005043 99.0
SRD2_k127_1015756_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1199.0
SRD2_k127_1015756_1 L-lactate permease K00427,K03303 - - 4.313e-276 859.0
SRD2_k127_1015756_10 Belongs to the peptidase S11 family K07262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006628 283.0
SRD2_k127_1015756_11 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001322 283.0
SRD2_k127_1015756_12 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000003244 245.0
SRD2_k127_1015756_13 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000006848 213.0
SRD2_k127_1015756_14 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000275 206.0
SRD2_k127_1015756_15 - - - - 0.0000000000000000000000000000000000000000000000001539 183.0
SRD2_k127_1015756_16 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000000000000000007475 178.0
SRD2_k127_1015756_2 Pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 6.941e-229 716.0
SRD2_k127_1015756_3 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 602.0
SRD2_k127_1015756_4 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 477.0
SRD2_k127_1015756_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009869 383.0
SRD2_k127_1015756_6 RNA polymerase sigma factor RpoH K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 344.0
SRD2_k127_1015756_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 353.0
SRD2_k127_1015756_8 Bacterial virulence factor lipase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 357.0
SRD2_k127_1015756_9 Transcriptional regulatory protein, C terminal K02483,K07663 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 317.0
SRD2_k127_1042558_0 Methionine synthase K00548 - 2.1.1.13 0.0 1603.0
SRD2_k127_1042558_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.654e-232 732.0
SRD2_k127_1042558_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 398.0
SRD2_k127_1042558_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 - 0.00000000000000000000000000000000000000000000000000000000000002079 230.0
SRD2_k127_1042558_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000008487 146.0
SRD2_k127_1042558_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000004235 104.0
SRD2_k127_11127_0 Thiamine pyrophosphate enzyme, central domain K04103 - 4.1.1.74 1.636e-257 805.0
SRD2_k127_11127_1 Oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 619.0
SRD2_k127_11127_10 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000125 272.0
SRD2_k127_11127_11 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000000001426 182.0
SRD2_k127_11127_12 acetyltransferase - - - 0.000000000000000000000000000000000002389 146.0
SRD2_k127_11127_2 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 601.0
SRD2_k127_11127_3 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 546.0
SRD2_k127_11127_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 420.0
SRD2_k127_11127_5 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 409.0
SRD2_k127_11127_6 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 348.0
SRD2_k127_11127_7 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 328.0
SRD2_k127_11127_8 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 305.0
SRD2_k127_11127_9 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 283.0
SRD2_k127_1141908_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 382.0
SRD2_k127_1141908_1 Histidine kinase K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 366.0
SRD2_k127_1141908_2 response regulator receiver K02667 - - 0.0000000000000000000000000000323 127.0
SRD2_k127_1154544_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.194e-214 674.0
SRD2_k127_1154544_1 Sulfotransferase family - - - 1.372e-204 647.0
SRD2_k127_1154544_10 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 392.0
SRD2_k127_1154544_11 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 312.0
SRD2_k127_1154544_12 Major Facilitator Superfamily K02445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 300.0
SRD2_k127_1154544_13 Peptidase C26 K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006439 278.0
SRD2_k127_1154544_14 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000022 272.0
SRD2_k127_1154544_15 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.0000000000000000000000000000000005959 131.0
SRD2_k127_1154544_2 Aldehyde dehydrogenase family - - - 1.373e-196 623.0
SRD2_k127_1154544_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 598.0
SRD2_k127_1154544_4 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 559.0
SRD2_k127_1154544_5 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 521.0
SRD2_k127_1154544_6 Extracellular solute-binding protein K02055,K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 504.0
SRD2_k127_1154544_7 Belongs to the ABC transporter superfamily K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 473.0
SRD2_k127_1154544_8 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 461.0
SRD2_k127_1154544_9 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 422.0
SRD2_k127_1165_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 2.721e-310 998.0
SRD2_k127_1165_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.051e-197 626.0
SRD2_k127_1165_10 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 351.0
SRD2_k127_1165_11 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 317.0
SRD2_k127_1165_12 PFAM MazG nucleotide pyrophosphohydrolase K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002808 284.0
SRD2_k127_1165_13 Histidine kinase K07637 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001589 284.0
SRD2_k127_1165_14 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000003944 209.0
SRD2_k127_1165_15 NUDIX domain - - - 0.000000000000000000000000000000000000000000000006729 180.0
SRD2_k127_1165_16 ABC transporter K02003 - - 0.0000000000000000000000000000000000001179 141.0
SRD2_k127_1165_17 hydrolase - - - 0.000000000000000000000000000212 123.0
SRD2_k127_1165_18 protein acetylation - - - 0.00000000000000000002584 98.0
SRD2_k127_1165_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 500.0
SRD2_k127_1165_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 486.0
SRD2_k127_1165_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 470.0
SRD2_k127_1165_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 421.0
SRD2_k127_1165_6 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 403.0
SRD2_k127_1165_7 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 379.0
SRD2_k127_1165_8 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 357.0
SRD2_k127_1165_9 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 351.0
SRD2_k127_1171775_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 597.0
SRD2_k127_1171775_1 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 576.0
SRD2_k127_1171775_10 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003707 274.0
SRD2_k127_1171775_11 MraW methylase family K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000004562 221.0
SRD2_k127_1171775_12 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000004859 150.0
SRD2_k127_1171775_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000749 84.0
SRD2_k127_1171775_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 482.0
SRD2_k127_1171775_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 436.0
SRD2_k127_1171775_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 426.0
SRD2_k127_1171775_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 391.0
SRD2_k127_1171775_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 377.0
SRD2_k127_1171775_7 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 379.0
SRD2_k127_1171775_8 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 357.0
SRD2_k127_1171775_9 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 353.0
SRD2_k127_1248580_0 small GTP-binding protein K02355 - - 1.529e-281 880.0
SRD2_k127_1248580_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 452.0
SRD2_k127_1248580_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 439.0
SRD2_k127_1248580_3 SpoVR like protein K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 443.0
SRD2_k127_1248580_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000001005 267.0
SRD2_k127_1248580_5 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000606 231.0
SRD2_k127_1248580_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000003806 196.0
SRD2_k127_1248580_7 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000009114 155.0
SRD2_k127_1248580_8 Glycosyl transferase, family 2 - - - 0.00000000000000006491 91.0
SRD2_k127_1250333_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.998e-264 824.0
SRD2_k127_1250333_1 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.868e-230 734.0
SRD2_k127_1250333_10 Cupin domain - - - 0.00000000000000000000000000000000000000000000000008867 182.0
SRD2_k127_1250333_11 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000003848 183.0
SRD2_k127_1250333_12 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000001149 156.0
SRD2_k127_1250333_13 membrane - - - 0.00000000000000000000000000000000005734 138.0
SRD2_k127_1250333_14 Eukaryotic cytochrome b561 - - - 0.00000000000000000000000003979 117.0
SRD2_k127_1250333_15 YceI-like domain - - - 0.00000000000000000000199 106.0
SRD2_k127_1250333_16 - - - - 0.00000000000012 82.0
SRD2_k127_1250333_2 Belongs to the peptidase S1B family - - - 3.035e-208 668.0
SRD2_k127_1250333_3 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 625.0
SRD2_k127_1250333_4 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 573.0
SRD2_k127_1250333_5 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 539.0
SRD2_k127_1250333_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 422.0
SRD2_k127_1250333_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 407.0
SRD2_k127_1250333_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 301.0
SRD2_k127_1250333_9 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000006227 228.0
SRD2_k127_1276769_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.09e-267 835.0
SRD2_k127_1276769_1 Helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 585.0
SRD2_k127_1276769_2 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 397.0
SRD2_k127_1276769_3 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 317.0
SRD2_k127_1276769_4 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000000000000000000000000001398 197.0
SRD2_k127_1276769_5 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000005229 92.0
SRD2_k127_1288070_0 transporter - - - 2.085e-268 841.0
SRD2_k127_1288070_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 6.046e-214 694.0
SRD2_k127_1288070_10 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 370.0
SRD2_k127_1288070_11 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 356.0
SRD2_k127_1288070_12 response regulator K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 305.0
SRD2_k127_1288070_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 292.0
SRD2_k127_1288070_14 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 307.0
SRD2_k127_1288070_15 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000001896 239.0
SRD2_k127_1288070_16 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000944 215.0
SRD2_k127_1288070_17 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000001893 206.0
SRD2_k127_1288070_18 helix_turn_helix ASNC type K05800 - - 0.0000000000000000000000000000000000000000000000000004404 188.0
SRD2_k127_1288070_19 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000003957 186.0
SRD2_k127_1288070_2 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 610.0
SRD2_k127_1288070_20 - - - - 0.00000000000000000000000000000000000000000002188 164.0
SRD2_k127_1288070_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000005392 165.0
SRD2_k127_1288070_22 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.0000000000000000000001665 99.0
SRD2_k127_1288070_23 PFAM Membrane protein of K08972 - - 0.000000000000000000000278 107.0
SRD2_k127_1288070_24 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000003266 66.0
SRD2_k127_1288070_25 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03116,K03117 - - 0.000000007383 63.0
SRD2_k127_1288070_26 Polyketide cyclase / dehydrase and lipid transport - - - 0.000002974 56.0
SRD2_k127_1288070_3 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 588.0
SRD2_k127_1288070_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 473.0
SRD2_k127_1288070_5 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 420.0
SRD2_k127_1288070_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 406.0
SRD2_k127_1288070_7 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 403.0
SRD2_k127_1288070_8 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 407.0
SRD2_k127_1288070_9 PFAM Alcohol dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 391.0
SRD2_k127_1306416_0 UPF0313 protein - - - 0.0 1083.0
SRD2_k127_1306416_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.279e-307 959.0
SRD2_k127_1306416_10 helix_turn_helix isocitrate lyase regulation K02624,K20539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000172 248.0
SRD2_k127_1306416_11 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000002475 232.0
SRD2_k127_1306416_12 DoxX-like family K15977 - - 0.000000000000000000000000000000000000000000000000000000000003966 218.0
SRD2_k127_1306416_13 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000003323 201.0
SRD2_k127_1306416_14 - - - - 0.00000000000000000000000000000000000000000002006 173.0
SRD2_k127_1306416_15 - - - - 0.00000000000000000000000000000000000000001028 160.0
SRD2_k127_1306416_16 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000006768 158.0
SRD2_k127_1306416_17 - - - - 0.0000000000000000000000000007303 117.0
SRD2_k127_1306416_18 - - - - 0.00000000000000000000000003212 109.0
SRD2_k127_1306416_19 Pkd domain containing protein K01337 - 3.4.21.50 0.0000000000000000000000003389 122.0
SRD2_k127_1306416_2 ATP-dependent helicase K03579 - 3.6.4.13 3.77e-271 865.0
SRD2_k127_1306416_20 peptidase M13 K07386 - - 0.000000000000000000000004796 110.0
SRD2_k127_1306416_21 - - - - 0.00000000000000000000001661 106.0
SRD2_k127_1306416_22 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000006351 92.0
SRD2_k127_1306416_23 - - - - 0.0000000000000006694 80.0
SRD2_k127_1306416_25 - - - - 0.000000000008197 74.0
SRD2_k127_1306416_26 protein phosphatase 2C domain protein - - - 0.00007865 48.0
SRD2_k127_1306416_3 Protein of unknown function (DUF1343) - - - 3.902e-212 674.0
SRD2_k127_1306416_4 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 553.0
SRD2_k127_1306416_5 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 467.0
SRD2_k127_1306416_6 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 411.0
SRD2_k127_1306416_7 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 315.0
SRD2_k127_1306416_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000214 275.0
SRD2_k127_1306416_9 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003772 261.0
SRD2_k127_1317501_0 PFAM CagE, TrbE, VirB component of type IV transporter system K03199,K12063,K12080 - - 3.47e-301 944.0
SRD2_k127_1317501_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 421.0
SRD2_k127_1317501_10 Conjugal transfer protein K03204,K20532 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007571 245.0
SRD2_k127_1317501_11 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.000000000000000000000000000000000000000000000000000000000002778 216.0
SRD2_k127_1317501_12 VirB8 protein K03203 - - 0.00000000000000000000000000000000000000000000000000000000001305 217.0
SRD2_k127_1317501_13 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.0000000000000000000000000000000000000000000000000000000001946 223.0
SRD2_k127_1317501_14 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000002244 158.0
SRD2_k127_1317501_15 Type IV secretory pathway, VirB3-like protein K03198 - - 0.0000000000000000000000000000000000000404 147.0
SRD2_k127_1317501_16 - - - - 0.0000000000000000000000000000000001884 138.0
SRD2_k127_1317501_17 PFAM type IV secretion system K03200 - - 0.00000000000000000000000000000002151 136.0
SRD2_k127_1317501_18 Single-strand binding protein family K03111 - - 0.0000000000000000000000000871 111.0
SRD2_k127_1317501_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 402.0
SRD2_k127_1317501_20 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000004921 81.0
SRD2_k127_1317501_21 Antidote-toxin recognition MazE, bacterial antitoxin K07172 - - 0.000001716 55.0
SRD2_k127_1317501_22 PFAM Relaxase mobilization nuclease family protein - - - 0.0008026 49.0
SRD2_k127_1317501_23 MobA/MobL family - - - 0.0008989 42.0
SRD2_k127_1317501_3 Type IV secretory pathway VirD4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 394.0
SRD2_k127_1317501_4 Type IV secretory pathway VirD4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 355.0
SRD2_k127_1317501_5 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 351.0
SRD2_k127_1317501_6 Type II/IV secretion system protein K03196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 329.0
SRD2_k127_1317501_7 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 316.0
SRD2_k127_1317501_8 Bacterial conjugation TrbI-like protein K03195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 329.0
SRD2_k127_1317501_9 PFAM TrbL VirB6 plasmid conjugal transfer protein K03201 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001259 287.0
SRD2_k127_1386799_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 536.0
SRD2_k127_1386799_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 467.0
SRD2_k127_1386799_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000009333 195.0
SRD2_k127_1386799_11 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000001855 193.0
SRD2_k127_1386799_12 membrane protein domain - - - 0.00000000000000000000000000000000000000000000009233 178.0
SRD2_k127_1386799_13 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000007583 156.0
SRD2_k127_1386799_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000001391 154.0
SRD2_k127_1386799_15 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000008374 139.0
SRD2_k127_1386799_16 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - 0.0000000000000000000000000006997 120.0
SRD2_k127_1386799_17 flagellar protein FliS K02422 - - 0.000000000000000000000000006638 114.0
SRD2_k127_1386799_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 463.0
SRD2_k127_1386799_3 With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 355.0
SRD2_k127_1386799_4 Flagellar motor protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 330.0
SRD2_k127_1386799_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 316.0
SRD2_k127_1386799_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000008734 228.0
SRD2_k127_1386799_7 diguanylate cyclase K13590,K21019 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000005659 232.0
SRD2_k127_1386799_8 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.00000000000000000000000000000000000000000000000000000000000000362 235.0
SRD2_k127_1386799_9 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000001387 225.0
SRD2_k127_1419338_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 6.685e-209 678.0
SRD2_k127_1419338_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000009627 188.0
SRD2_k127_1419338_2 Sh3 type 3 domain protein - - - 0.0000000000000000000000000000000000000001455 163.0
SRD2_k127_1419338_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 0.00000000000000226 78.0
SRD2_k127_1419338_5 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000001437 59.0
SRD2_k127_1441197_0 Sortilin, neurotensin receptor 3, - - - 0.0 1301.0
SRD2_k127_1441197_1 Sortilin, neurotensin receptor 3, - - - 0.0 1211.0
SRD2_k127_1441197_10 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 528.0
SRD2_k127_1441197_11 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 531.0
SRD2_k127_1441197_12 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 415.0
SRD2_k127_1441197_13 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 398.0
SRD2_k127_1441197_14 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 327.0
SRD2_k127_1441197_15 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 302.0
SRD2_k127_1441197_16 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000403 273.0
SRD2_k127_1441197_17 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000006592 264.0
SRD2_k127_1441197_18 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000081 240.0
SRD2_k127_1441197_19 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000009183 217.0
SRD2_k127_1441197_2 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.501e-314 976.0
SRD2_k127_1441197_20 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000001154 215.0
SRD2_k127_1441197_21 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000001085 196.0
SRD2_k127_1441197_22 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000001929 203.0
SRD2_k127_1441197_23 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000006461 194.0
SRD2_k127_1441197_24 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.0000000000000000000000000000000000000000000000001325 198.0
SRD2_k127_1441197_25 TraB family K09973 - - 0.00000000000000000000000000000000000000000428 166.0
SRD2_k127_1441197_26 glycosyl - - - 0.00000000000000000000000000000000000000008558 165.0
SRD2_k127_1441197_27 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000009334 145.0
SRD2_k127_1441197_28 PFAM CAAX amino terminal protease family K07052 - - 0.00000000000000000000000000000000002862 151.0
SRD2_k127_1441197_29 TRANSCRIPTIONal - - - 0.00000000000000000005727 93.0
SRD2_k127_1441197_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 4.506e-281 880.0
SRD2_k127_1441197_30 Zinc-finger domain - - - 0.0000000000000000008831 100.0
SRD2_k127_1441197_32 Displays ATPase and GTPase activities K06958 - - 0.000001989 50.0
SRD2_k127_1441197_4 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.939e-241 777.0
SRD2_k127_1441197_5 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 616.0
SRD2_k127_1441197_6 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 604.0
SRD2_k127_1441197_7 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 566.0
SRD2_k127_1441197_8 Penicillin acylase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 582.0
SRD2_k127_1441197_9 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 538.0
SRD2_k127_1444413_0 Lon protease (S16) C-terminal proteolytic domain K01338 - 3.4.21.53 7.205e-318 994.0
SRD2_k127_1444413_1 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 1.566e-239 765.0
SRD2_k127_1444413_10 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000006738 104.0
SRD2_k127_1444413_12 cellulase activity - - - 0.00000001722 68.0
SRD2_k127_1444413_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 494.0
SRD2_k127_1444413_3 PFAM Peptidase S53, propeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 395.0
SRD2_k127_1444413_4 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004906 256.0
SRD2_k127_1444413_5 Signal peptidase, peptidase S26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005977 253.0
SRD2_k127_1444413_6 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000004626 239.0
SRD2_k127_1444413_7 Thioredoxin-like domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000001091 212.0
SRD2_k127_1444413_8 PFAM 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000001417 205.0
SRD2_k127_1444413_9 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000001962 155.0
SRD2_k127_1484915_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 1.48e-306 960.0
SRD2_k127_1484915_1 - - - - 8.791e-289 913.0
SRD2_k127_1484915_10 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000001904 226.0
SRD2_k127_1484915_11 transmembrane transporter activity K08225 - - 0.000000000000000000000000000000000000000000000000000000000000004913 233.0
SRD2_k127_1484915_12 Conjugal transfer protein - - - 0.00000000000000000000000000000000000000000000000000004405 199.0
SRD2_k127_1484915_13 transcriptional regulator - - - 0.0000000000000000000000000000000001914 144.0
SRD2_k127_1484915_14 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000000000002497 130.0
SRD2_k127_1484915_15 transcriptional regulator - - - 0.00000000000000000000000000000003231 134.0
SRD2_k127_1484915_16 - - - - 0.0000000000000000000000002799 109.0
SRD2_k127_1484915_17 COG2863 Cytochrome c553 - - - 0.000000000000000000000009703 103.0
SRD2_k127_1484915_18 Belongs to the ompA family - - - 0.0000000000000000000008009 103.0
SRD2_k127_1484915_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 6.497e-246 770.0
SRD2_k127_1484915_20 CDP-archaeol synthase K19664 - 2.7.7.67 0.00000000000000000002976 99.0
SRD2_k127_1484915_21 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000007273 94.0
SRD2_k127_1484915_22 - - - - 0.00000000000000005929 81.0
SRD2_k127_1484915_23 Protein required for attachment to host cells - - - 0.00000000000000007587 88.0
SRD2_k127_1484915_24 competence protein - - - 0.0000000000000001602 88.0
SRD2_k127_1484915_25 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000004151 75.0
SRD2_k127_1484915_28 - - - - 0.0008582 48.0
SRD2_k127_1484915_3 Belongs to the heme-copper respiratory oxidase family K04561 - 1.7.2.5 6.193e-213 669.0
SRD2_k127_1484915_4 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 577.0
SRD2_k127_1484915_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 506.0
SRD2_k127_1484915_6 COG0076 Glutamate decarboxylase and related PLP-dependent proteins K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 400.0
SRD2_k127_1484915_7 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 353.0
SRD2_k127_1484915_8 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 320.0
SRD2_k127_1484915_9 Cytochrome c K02305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002888 282.0
SRD2_k127_152832_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 6.136e-194 627.0
SRD2_k127_152832_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 347.0
SRD2_k127_152832_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005611 273.0
SRD2_k127_152832_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000004226 214.0
SRD2_k127_152832_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000004373 202.0
SRD2_k127_1601047_0 PFAM Xylulose 5-phosphate Fructose 6-phosphate phosphoketolase, N-terminal - - - 0.0 1210.0
SRD2_k127_1601047_1 Amidase - - - 2.085e-273 854.0
SRD2_k127_1601047_10 Evidence 4 Homologs of previously reported genes of - - - 0.0000001878 60.0
SRD2_k127_1601047_2 Transport of potassium into the cell K03549 - - 2.063e-256 804.0
SRD2_k127_1601047_3 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 591.0
SRD2_k127_1601047_4 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 516.0
SRD2_k127_1601047_5 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 309.0
SRD2_k127_1601047_6 - - - - 0.00000000000000000000000000000000000000000000006762 183.0
SRD2_k127_1601047_7 universal stress protein K14055 - - 0.000000000000000000000000000000008156 140.0
SRD2_k127_1601047_8 universal stress protein K14055 - - 0.0000000000000000000000000000001553 138.0
SRD2_k127_1601047_9 Cytochrome c - - - 0.0000000000000003635 79.0
SRD2_k127_1605351_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 499.0
SRD2_k127_1605351_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 367.0
SRD2_k127_1605351_2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 335.0
SRD2_k127_1605351_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001622 287.0
SRD2_k127_1605351_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000007817 187.0
SRD2_k127_187394_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1454.0
SRD2_k127_187394_1 Major facilitator Superfamily - - - 1.396e-249 781.0
SRD2_k127_187394_10 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 366.0
SRD2_k127_187394_11 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 371.0
SRD2_k127_187394_12 Lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 349.0
SRD2_k127_187394_13 Response regulator receiver K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 345.0
SRD2_k127_187394_14 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 323.0
SRD2_k127_187394_15 deacetylase K06986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 304.0
SRD2_k127_187394_16 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 297.0
SRD2_k127_187394_17 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 312.0
SRD2_k127_187394_18 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006834 277.0
SRD2_k127_187394_19 PFAM ROK family protein K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000009853 263.0
SRD2_k127_187394_2 CBS domain containing protein - - - 5.826e-226 725.0
SRD2_k127_187394_20 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004155 260.0
SRD2_k127_187394_21 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002873 249.0
SRD2_k127_187394_22 polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000172 248.0
SRD2_k127_187394_23 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002786 233.0
SRD2_k127_187394_24 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000002538 222.0
SRD2_k127_187394_25 CobQ/CobB/MinD/ParA nucleotide binding domain K08252,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000002432 226.0
SRD2_k127_187394_26 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000001803 218.0
SRD2_k127_187394_27 Signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000002941 220.0
SRD2_k127_187394_28 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000001164 214.0
SRD2_k127_187394_29 Histidine kinase K05962 - 2.7.13.1 0.0000000000000000000000000000000000000000000000000000000004086 220.0
SRD2_k127_187394_3 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 610.0
SRD2_k127_187394_30 radical SAM domain protein K04034 GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000007541 222.0
SRD2_k127_187394_31 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000001742 202.0
SRD2_k127_187394_32 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000003006 213.0
SRD2_k127_187394_33 G-rich domain on putative tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000954 205.0
SRD2_k127_187394_34 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000003251 184.0
SRD2_k127_187394_35 Single Cache domain 2 K02480 - 2.7.13.3 0.0000000000000000000000000000000000000000000003971 192.0
SRD2_k127_187394_36 diguanylate cyclase - - - 0.000000000000000000000000000000000000000002448 170.0
SRD2_k127_187394_37 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000001538 164.0
SRD2_k127_187394_38 transferase activity, transferring amino-acyl groups - - - 0.000000000000000000000000000000000913 145.0
SRD2_k127_187394_39 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000004016 149.0
SRD2_k127_187394_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 598.0
SRD2_k127_187394_40 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000001921 137.0
SRD2_k127_187394_41 - - - - 0.0000000000000000000000000000002112 135.0
SRD2_k127_187394_42 Putative beta-barrel porin 2 - - - 0.0000000000000000000000000000008042 141.0
SRD2_k127_187394_43 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000118 131.0
SRD2_k127_187394_44 OsmC-like protein K07397 - - 0.000000000000000000000000002802 115.0
SRD2_k127_187394_45 methyltransferase - - - 0.00000000000000000000003212 111.0
SRD2_k127_187394_46 Polysaccharide lyase - - - 0.00000000000000000001003 102.0
SRD2_k127_187394_47 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000001221 104.0
SRD2_k127_187394_48 - - - - 0.0000000000000000003488 101.0
SRD2_k127_187394_49 Domain of unknown function (DUF4874) - - - 0.00000000000000001299 98.0
SRD2_k127_187394_5 COG1020 Non-ribosomal peptide synthetase modules and related proteins K02364 - 6.3.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 575.0
SRD2_k127_187394_50 response regulator - - - 0.000000000000003668 80.0
SRD2_k127_187394_51 ubiE/COQ5 methyltransferase family - - - 0.0000000000002816 79.0
SRD2_k127_187394_52 Glycosyl transferase family 21 - - - 0.00000003198 66.0
SRD2_k127_187394_54 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000008098 56.0
SRD2_k127_187394_6 transferase activity, transferring glycosyl groups K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 561.0
SRD2_k127_187394_7 COG2148 Sugar transferases involved in lipopolysaccharide synthesis K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 494.0
SRD2_k127_187394_8 TIGRFAM diguanylate cyclase (GGDEF) domain K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 477.0
SRD2_k127_187394_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 395.0
SRD2_k127_2013494_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 404.0
SRD2_k127_2013494_1 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 364.0
SRD2_k127_2013494_2 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 287.0
SRD2_k127_2013494_3 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000001032 225.0
SRD2_k127_2013494_4 - - - - 0.0003277 47.0
SRD2_k127_2030775_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1127.0
SRD2_k127_2030775_1 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 506.0
SRD2_k127_2030775_2 PFAM AsmA family protein K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 326.0
SRD2_k127_2030775_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 323.0
SRD2_k127_2030775_4 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000002815 191.0
SRD2_k127_2030775_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000005692 135.0
SRD2_k127_2030775_6 Modulates RecA activity K03565 - - 0.000000000000000000000000000609 119.0
SRD2_k127_2030775_7 Transglycosylase associated protein - - - 0.000000000000000000000000001378 114.0
SRD2_k127_2030775_9 Recombinase zinc beta ribbon domain - - - 0.00027 48.0
SRD2_k127_2071812_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 6.386e-277 875.0
SRD2_k127_2071812_1 WD40-like Beta Propeller Repeat - - - 8.644e-262 827.0
SRD2_k127_2071812_10 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 385.0
SRD2_k127_2071812_11 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 301.0
SRD2_k127_2071812_12 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 295.0
SRD2_k127_2071812_13 Putative sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 294.0
SRD2_k127_2071812_14 TIGRFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002832 276.0
SRD2_k127_2071812_15 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001223 252.0
SRD2_k127_2071812_16 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000161 235.0
SRD2_k127_2071812_17 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000003272 214.0
SRD2_k127_2071812_18 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.000000000000000000000000000000000000000000000000000001216 209.0
SRD2_k127_2071812_19 Hydrolase K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000000000000001996 181.0
SRD2_k127_2071812_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.124e-226 722.0
SRD2_k127_2071812_20 - - - - 0.00000000000000000000000000000000000000005152 158.0
SRD2_k127_2071812_21 - - - - 0.00000000000000000000000000000000000001817 152.0
SRD2_k127_2071812_22 PadR family transcriptional regulator K10947 - - 0.00000000000000000000000000000000005827 136.0
SRD2_k127_2071812_23 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000002095 136.0
SRD2_k127_2071812_24 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000005902 136.0
SRD2_k127_2071812_25 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000001307 114.0
SRD2_k127_2071812_26 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000002041 94.0
SRD2_k127_2071812_27 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000003698 77.0
SRD2_k127_2071812_28 Late embryogenesis abundant protein - - - 0.00000000001109 72.0
SRD2_k127_2071812_3 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 598.0
SRD2_k127_2071812_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 556.0
SRD2_k127_2071812_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 485.0
SRD2_k127_2071812_6 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 468.0
SRD2_k127_2071812_7 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 458.0
SRD2_k127_2071812_8 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 449.0
SRD2_k127_2071812_9 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 423.0
SRD2_k127_2092384_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 7.932e-302 938.0
SRD2_k127_2092384_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.95e-226 711.0
SRD2_k127_2092384_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 2.604e-209 668.0
SRD2_k127_2092384_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 472.0
SRD2_k127_2092384_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001001 288.0
SRD2_k127_2092384_5 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000002553 198.0
SRD2_k127_2092384_6 Histidine kinase - - - 0.0000000000000008375 83.0
SRD2_k127_2092384_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000001491 79.0
SRD2_k127_2106305_0 Hydantoinase/oxoprolinase N-terminal region - - - 0.0 1198.0
SRD2_k127_2106305_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 3.302e-231 721.0
SRD2_k127_2106305_10 SMART Peptidoglycan-binding Lysin subgroup K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 367.0
SRD2_k127_2106305_11 Protein of unknown function (DUF1302) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 338.0
SRD2_k127_2106305_12 Phage tail sheath C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 314.0
SRD2_k127_2106305_13 Small-conductance mechanosensitive channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 308.0
SRD2_k127_2106305_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 293.0
SRD2_k127_2106305_15 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001958 279.0
SRD2_k127_2106305_16 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002578 270.0
SRD2_k127_2106305_17 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000000000000000000000000000000009172 231.0
SRD2_k127_2106305_18 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000001528 230.0
SRD2_k127_2106305_19 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000001646 194.0
SRD2_k127_2106305_2 exporters of the RND superfamily K07003 - - 1.161e-230 744.0
SRD2_k127_2106305_20 TPM domain - - - 0.0000000000000000000000000000000000000000000000000004587 188.0
SRD2_k127_2106305_21 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000001004 184.0
SRD2_k127_2106305_22 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000002979 171.0
SRD2_k127_2106305_23 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000003693 168.0
SRD2_k127_2106305_24 Uncharacterised protein family (UPF0227) - - - 0.0000000000000000000000000000000000000000225 160.0
SRD2_k127_2106305_25 4-hydroxybenzoyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000007452 143.0
SRD2_k127_2106305_26 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000000007351 135.0
SRD2_k127_2106305_27 Predicted membrane protein (DUF2214) - - - 0.0000000000000000000000000000004895 131.0
SRD2_k127_2106305_28 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000001828 121.0
SRD2_k127_2106305_29 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000005159 96.0
SRD2_k127_2106305_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.857e-229 717.0
SRD2_k127_2106305_30 small protein containing a coiled-coil domain - - - 0.000000000001301 76.0
SRD2_k127_2106305_31 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000001438 68.0
SRD2_k127_2106305_32 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000737 74.0
SRD2_k127_2106305_33 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000003104 59.0
SRD2_k127_2106305_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 4.235e-208 659.0
SRD2_k127_2106305_5 Belongs to the GARS family K01945,K13713 - 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 532.0
SRD2_k127_2106305_6 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 524.0
SRD2_k127_2106305_7 Protein of unknown function (DUF1329) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 494.0
SRD2_k127_2106305_8 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 470.0
SRD2_k127_2106305_9 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 384.0
SRD2_k127_2118430_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1498.0
SRD2_k127_2118430_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 4.197e-195 627.0
SRD2_k127_2118430_10 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000002018 190.0
SRD2_k127_2118430_11 ferredoxin K04755 - - 0.000000000000000000000000000004225 121.0
SRD2_k127_2118430_12 glycosyl transferase, family 39 - - - 0.00000000000000000000000000005526 134.0
SRD2_k127_2118430_13 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000000000000003558 116.0
SRD2_k127_2118430_14 YKOF-related Family - - - 0.000000000001084 72.0
SRD2_k127_2118430_15 Regulator of ribonuclease activity B - - - 0.00008039 50.0
SRD2_k127_2118430_2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 540.0
SRD2_k127_2118430_3 Amino acid permease K03293 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 438.0
SRD2_k127_2118430_4 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 341.0
SRD2_k127_2118430_5 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003161 287.0
SRD2_k127_2118430_6 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517,K12974 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000002481 270.0
SRD2_k127_2118430_7 PFAM ABC transporter related K05776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003139 267.0
SRD2_k127_2118430_8 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000001676 236.0
SRD2_k127_2118430_9 Phenazine biosynthesis protein PhzF - - - 0.00000000000000000000000000000000000000000000000000000000000006314 224.0
SRD2_k127_2158824_0 response regulator receiver K02487,K06596 - - 0.0 1106.0
SRD2_k127_2158824_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 2.119e-214 686.0
SRD2_k127_2158824_10 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000398 239.0
SRD2_k127_2158824_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000006225 235.0
SRD2_k127_2158824_12 - - - - 0.000000000000000000000000000000000000000000000000000000000005911 216.0
SRD2_k127_2158824_13 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000002674 174.0
SRD2_k127_2158824_14 MerR, DNA binding K13639 - - 0.0000000000000000000000000000009682 126.0
SRD2_k127_2158824_15 TIR domain - - - 0.00000000000000000000000002717 126.0
SRD2_k127_2158824_16 chemotaxis signal transduction protein K06598 - - 0.0000000000000000000006809 103.0
SRD2_k127_2158824_17 - - - - 0.000001337 62.0
SRD2_k127_2158824_2 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 418.0
SRD2_k127_2158824_3 Inositol monophosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 290.0
SRD2_k127_2158824_4 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004151 280.0
SRD2_k127_2158824_5 chemotaxis protein K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007355 273.0
SRD2_k127_2158824_6 adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000002869 263.0
SRD2_k127_2158824_7 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000002816 251.0
SRD2_k127_2158824_8 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001195 250.0
SRD2_k127_2158824_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001305 268.0
SRD2_k127_2175965_0 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 4.873e-274 856.0
SRD2_k127_2175965_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 540.0
SRD2_k127_2175965_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 313.0
SRD2_k127_2175965_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 312.0
SRD2_k127_2175965_4 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001708 247.0
SRD2_k127_2211265_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 3.586e-304 947.0
SRD2_k127_2211265_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.968e-236 740.0
SRD2_k127_2211265_10 succinate dehydrogenase K00241 - - 0.00000000000000000005805 94.0
SRD2_k127_2211265_11 belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000002366 77.0
SRD2_k127_2211265_12 Flavinator of succinate dehydrogenase K09159 - - 0.0000000001067 67.0
SRD2_k127_2211265_14 PFAM Anti sigma-E protein RseA K03597 - - 0.0003443 52.0
SRD2_k127_2211265_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 4.896e-205 653.0
SRD2_k127_2211265_3 succinate dehydrogenase fumarate reductase K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 398.0
SRD2_k127_2211265_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002304 253.0
SRD2_k127_2211265_5 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000002299 171.0
SRD2_k127_2211265_6 MucB/RseB C-terminal domain - - - 0.0000000000000000000000000000000000000000000002663 184.0
SRD2_k127_2211265_7 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000003398 156.0
SRD2_k127_2211265_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000004352 122.0
SRD2_k127_2211265_9 succinate dehydrogenase K00242 - - 0.000000000000000000000000000004759 130.0
SRD2_k127_2262351_0 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 6.257e-201 636.0
SRD2_k127_2262351_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.654e-200 631.0
SRD2_k127_2262351_10 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000003542 124.0
SRD2_k127_2262351_11 TIGRFAM TIGR02449 family protein K09892 - - 0.000000000003697 68.0
SRD2_k127_2262351_2 Belongs to the GcvP family K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 605.0
SRD2_k127_2262351_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 446.0
SRD2_k127_2262351_4 hydroxylase K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 355.0
SRD2_k127_2262351_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003721 279.0
SRD2_k127_2262351_6 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003551 274.0
SRD2_k127_2262351_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000002295 173.0
SRD2_k127_2262351_8 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000001525 143.0
SRD2_k127_2262351_9 Belongs to the UPF0149 family K09895 - - 0.00000000000000000000000000000000882 134.0
SRD2_k127_230889_0 AcrB/AcrD/AcrF family - - - 0.0 1532.0
SRD2_k127_230889_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1006.0
SRD2_k127_230889_10 TIGRFAM diguanylate cyclase (GGDEF) domain K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 475.0
SRD2_k127_230889_11 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 399.0
SRD2_k127_230889_12 COG0665 Glycine D-amino acid oxidases (deaminating) K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 374.0
SRD2_k127_230889_13 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 364.0
SRD2_k127_230889_14 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 342.0
SRD2_k127_230889_15 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 315.0
SRD2_k127_230889_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003903 280.0
SRD2_k127_230889_17 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000001863 250.0
SRD2_k127_230889_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000233 235.0
SRD2_k127_230889_19 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000004458 212.0
SRD2_k127_230889_2 Sodium:solute symporter family K03307 - - 7.683e-263 816.0
SRD2_k127_230889_20 Thiol disulfide interchange protein K02199 - - 0.000000000000000000000000000000000000000000000000003764 189.0
SRD2_k127_230889_21 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000001413 192.0
SRD2_k127_230889_22 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000001053 172.0
SRD2_k127_230889_23 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678 - 0.000000000000000000000000000000000000000000001752 174.0
SRD2_k127_230889_24 pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000000000000000002006 165.0
SRD2_k127_230889_25 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K08084 - - 0.0000000000000000000000000000000001621 140.0
SRD2_k127_230889_26 Type IV Pilus-assembly protein W K02672 - - 0.00000000000000000000000000000002243 136.0
SRD2_k127_230889_27 Cytochrome C biogenesis K02200 - - 0.0000000000000000000000000000002343 139.0
SRD2_k127_230889_28 subunit of a heme lyase K02200 - - 0.00000000000000000000000002344 121.0
SRD2_k127_230889_29 Protein of unknown function (DUF3311) - - - 0.000000000000000000000006742 103.0
SRD2_k127_230889_3 Sugar (and other) transporter - - - 9.719e-241 749.0
SRD2_k127_230889_30 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02673 - - 0.00000000000000000000008033 113.0
SRD2_k127_230889_31 Stress-induced bacterial acidophilic repeat motif - - - 0.000000000000000000000146 103.0
SRD2_k127_230889_32 Diguanylate cyclase - - - 0.0000000000000000002699 102.0
SRD2_k127_230889_33 ThiS family K03154 - - 0.00000000000000001131 83.0
SRD2_k127_230889_35 TIGRFAM type IV pilus modification protein PilV K02671 - - 0.000001569 58.0
SRD2_k127_230889_4 Neisseria PilC beta-propeller domain K02674 - - 9.123e-238 789.0
SRD2_k127_230889_5 Cytochrome C biogenesis K02198 - - 1.367e-219 703.0
SRD2_k127_230889_6 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 576.0
SRD2_k127_230889_7 PFAM ribonuclease II K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 564.0
SRD2_k127_230889_8 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 499.0
SRD2_k127_230889_9 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 466.0
SRD2_k127_2332455_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1039.0
SRD2_k127_2332455_1 Peptidase family M3 K01414 - 3.4.24.70 9.655e-239 756.0
SRD2_k127_2332455_10 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 428.0
SRD2_k127_2332455_11 abc transporter atp-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 368.0
SRD2_k127_2332455_12 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 358.0
SRD2_k127_2332455_13 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 347.0
SRD2_k127_2332455_14 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 340.0
SRD2_k127_2332455_15 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 329.0
SRD2_k127_2332455_16 PFAM Fructosamine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 304.0
SRD2_k127_2332455_17 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 300.0
SRD2_k127_2332455_18 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 300.0
SRD2_k127_2332455_19 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 286.0
SRD2_k127_2332455_2 FAD binding domain - - - 1.952e-231 730.0
SRD2_k127_2332455_20 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000253 302.0
SRD2_k127_2332455_21 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005522 270.0
SRD2_k127_2332455_22 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001601 279.0
SRD2_k127_2332455_23 Exodeoxyribonuclease IX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001994 277.0
SRD2_k127_2332455_24 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002804 277.0
SRD2_k127_2332455_25 peptidoglycan-binding protein, lysm - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005101 277.0
SRD2_k127_2332455_26 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007621 261.0
SRD2_k127_2332455_27 COG1309 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000007939 242.0
SRD2_k127_2332455_28 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000001553 225.0
SRD2_k127_2332455_29 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.000000000000000000000000000000000000000000000000000004953 201.0
SRD2_k127_2332455_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.965e-229 731.0
SRD2_k127_2332455_30 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.000000000000000000000000000000000000000000000000008635 184.0
SRD2_k127_2332455_31 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000003062 171.0
SRD2_k127_2332455_32 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000009659 162.0
SRD2_k127_2332455_33 MlaD protein K02067,K06192 - - 0.000000000000000000000000000000000000000008569 167.0
SRD2_k127_2332455_34 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000000001797 155.0
SRD2_k127_2332455_35 - - - - 0.00000000000000000000000000000000000007302 145.0
SRD2_k127_2332455_36 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000004191 142.0
SRD2_k127_2332455_37 Sporulation related domain - - - 0.0000000000000000000000000003385 121.0
SRD2_k127_2332455_38 PFAM TfoX N-terminal domain K07343 - - 0.0000000000000000000000000003641 118.0
SRD2_k127_2332455_39 - K01992 - - 0.000000000000000000000000001994 126.0
SRD2_k127_2332455_4 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.127e-213 677.0
SRD2_k127_2332455_40 Protein of unknown function (DUF3106) - - - 0.000000000000000000001126 103.0
SRD2_k127_2332455_41 Domain of unknown function (DUF4390) - - - 0.00000005165 62.0
SRD2_k127_2332455_42 ABC transporter K18480 - - 0.0000001222 63.0
SRD2_k127_2332455_43 - - - - 0.0005063 50.0
SRD2_k127_2332455_5 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 613.0
SRD2_k127_2332455_6 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 582.0
SRD2_k127_2332455_7 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 513.0
SRD2_k127_2332455_8 sensor diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 453.0
SRD2_k127_2332455_9 response regulator receiver K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 433.0
SRD2_k127_2368234_0 PFAM peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 2.702e-312 989.0
SRD2_k127_2368234_1 MBOAT, membrane-bound O-acyltransferase family - - - 8.741e-267 827.0
SRD2_k127_2368234_10 COG0457 FOG TPR repeat - - - 0.0002547 45.0
SRD2_k127_2368234_2 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 608.0
SRD2_k127_2368234_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 444.0
SRD2_k127_2368234_4 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 451.0
SRD2_k127_2368234_5 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 416.0
SRD2_k127_2368234_6 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000002574 234.0
SRD2_k127_2368234_7 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000001331 145.0
SRD2_k127_2368234_8 TIR domain - - - 0.0000000000000000000000000005382 131.0
SRD2_k127_2368234_9 peptidyl-tyrosine sulfation - - - 0.0000000000000001374 82.0
SRD2_k127_2410767_0 succinyl-diaminopimelate desuccinylase activity - - - 1.064e-211 683.0
SRD2_k127_2410767_1 receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 520.0
SRD2_k127_2410767_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000002126 173.0
SRD2_k127_2410767_3 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000000000005797 138.0
SRD2_k127_2410767_4 Sporulation related domain - - - 0.000000001216 68.0
SRD2_k127_2410767_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000002317 53.0
SRD2_k127_2432206_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1200.0
SRD2_k127_2432206_1 Required for chromosome condensation and partitioning K03529 - - 2.592e-300 962.0
SRD2_k127_2432206_10 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 310.0
SRD2_k127_2432206_11 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001371 282.0
SRD2_k127_2432206_12 reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002825 269.0
SRD2_k127_2432206_13 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009224 270.0
SRD2_k127_2432206_14 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000001776 239.0
SRD2_k127_2432206_15 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000001083 228.0
SRD2_k127_2432206_16 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000004175 203.0
SRD2_k127_2432206_17 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000007318 185.0
SRD2_k127_2432206_18 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000002018 185.0
SRD2_k127_2432206_19 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.0000000000000000000000000000000000000000000002192 177.0
SRD2_k127_2432206_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.153e-246 782.0
SRD2_k127_2432206_20 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000002069 156.0
SRD2_k127_2432206_21 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000001025 136.0
SRD2_k127_2432206_22 TIGRFAM Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.000000000000000000000000000001087 124.0
SRD2_k127_2432206_23 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000001457 100.0
SRD2_k127_2432206_24 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.000000000007034 76.0
SRD2_k127_2432206_25 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000424 73.0
SRD2_k127_2432206_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 601.0
SRD2_k127_2432206_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 506.0
SRD2_k127_2432206_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00220,K00800 - 1.3.1.12,1.3.1.43,2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 484.0
SRD2_k127_2432206_6 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 451.0
SRD2_k127_2432206_7 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 450.0
SRD2_k127_2432206_8 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 394.0
SRD2_k127_2432206_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 339.0
SRD2_k127_2504022_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1126.0
SRD2_k127_2504022_1 Ammonium transporter K03320 - - 1.209e-228 717.0
SRD2_k127_2504022_10 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009619 316.0
SRD2_k127_2504022_11 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 317.0
SRD2_k127_2504022_12 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 312.0
SRD2_k127_2504022_13 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 306.0
SRD2_k127_2504022_14 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000001394 274.0
SRD2_k127_2504022_15 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002398 270.0
SRD2_k127_2504022_16 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000001205 269.0
SRD2_k127_2504022_17 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002069 275.0
SRD2_k127_2504022_18 NAD(P)H-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007317 252.0
SRD2_k127_2504022_19 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000008582 256.0
SRD2_k127_2504022_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 8.989e-200 641.0
SRD2_k127_2504022_20 Response regulator of the LytR AlgR family K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000992 249.0
SRD2_k127_2504022_21 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000004885 243.0
SRD2_k127_2504022_22 LysR substrate binding domain K18900 - - 0.000000000000000000000000000000000000000000000000000000000000000000005771 246.0
SRD2_k127_2504022_23 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000004047 248.0
SRD2_k127_2504022_24 COG2863 Cytochrome c553 - - - 0.00000000000000000000000000000000000000000000000008996 187.0
SRD2_k127_2504022_25 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000007444 186.0
SRD2_k127_2504022_26 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000008557 175.0
SRD2_k127_2504022_27 - - - - 0.00000000000000000000000000000000000000000000121 175.0
SRD2_k127_2504022_28 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000003981 172.0
SRD2_k127_2504022_29 SMART CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000000001081 152.0
SRD2_k127_2504022_3 phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 531.0
SRD2_k127_2504022_30 membrane - - - 0.0000000000000000000000000000000000305 138.0
SRD2_k127_2504022_31 Thiol disulfide interchange protein K03673 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000001968 144.0
SRD2_k127_2504022_32 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000006777 136.0
SRD2_k127_2504022_33 PFAM RNA recognition motif - - - 0.00000000000000000000000000004357 121.0
SRD2_k127_2504022_34 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000003843 121.0
SRD2_k127_2504022_35 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000002451 113.0
SRD2_k127_2504022_36 Membrane fusogenic activity K09806 - - 0.000000000000002274 79.0
SRD2_k127_2504022_37 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.00000001644 55.0
SRD2_k127_2504022_38 Outer membrane protein beta-barrel domain - - - 0.0000006914 60.0
SRD2_k127_2504022_39 PFAM OmpA domain protein transmembrane region-containing protein K03286 - - 0.000006553 55.0
SRD2_k127_2504022_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 509.0
SRD2_k127_2504022_41 Domain of unknown function (DUF4124) - - - 0.0007391 53.0
SRD2_k127_2504022_5 magnesium chelatase K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 470.0
SRD2_k127_2504022_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 459.0
SRD2_k127_2504022_7 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 415.0
SRD2_k127_2504022_8 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 372.0
SRD2_k127_2504022_9 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 340.0
SRD2_k127_2512493_0 dehydrogenase, E1 component K11381 - 1.2.4.4 3.011e-285 894.0
SRD2_k127_2512493_1 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 9.991e-273 865.0
SRD2_k127_2512493_10 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 475.0
SRD2_k127_2512493_11 Belongs to the cysteine synthase cystathionine beta- synthase family K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 463.0
SRD2_k127_2512493_12 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 451.0
SRD2_k127_2512493_13 Threonine synthase N terminus K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 439.0
SRD2_k127_2512493_14 Pfam Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 418.0
SRD2_k127_2512493_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 408.0
SRD2_k127_2512493_16 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 408.0
SRD2_k127_2512493_17 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 399.0
SRD2_k127_2512493_18 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 400.0
SRD2_k127_2512493_19 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 384.0
SRD2_k127_2512493_2 phenylacetic acid degradation protein K02618 - 1.2.1.91,3.3.2.12 6.969e-269 844.0
SRD2_k127_2512493_20 in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon K13634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 376.0
SRD2_k127_2512493_21 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 371.0
SRD2_k127_2512493_22 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 354.0
SRD2_k127_2512493_23 enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 343.0
SRD2_k127_2512493_24 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 325.0
SRD2_k127_2512493_25 Preprotein translocase subunit TatD K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 322.0
SRD2_k127_2512493_26 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 320.0
SRD2_k127_2512493_27 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 303.0
SRD2_k127_2512493_28 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 293.0
SRD2_k127_2512493_29 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 290.0
SRD2_k127_2512493_3 reductase 4Fe-4S K00381 - 1.8.1.2 4.262e-222 704.0
SRD2_k127_2512493_30 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 295.0
SRD2_k127_2512493_31 Oxidoreductase FAD-binding domain K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001441 290.0
SRD2_k127_2512493_32 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004047 281.0
SRD2_k127_2512493_33 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000006929 268.0
SRD2_k127_2512493_34 pteridine-dependent deoxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002753 263.0
SRD2_k127_2512493_35 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000001419 244.0
SRD2_k127_2512493_36 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006351 244.0
SRD2_k127_2512493_37 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000001188 219.0
SRD2_k127_2512493_38 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000000307 210.0
SRD2_k127_2512493_39 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000003654 198.0
SRD2_k127_2512493_4 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 8.483e-204 658.0
SRD2_k127_2512493_40 phenylacetate-CoA oxygenase, PaaJ subunit K02612 - - 0.0000000000000000000000000000000000000000000000001029 188.0
SRD2_k127_2512493_41 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000001309 181.0
SRD2_k127_2512493_42 COG1522 Transcriptional regulators K03719,K05800 - - 0.000000000000000000000000000000000000000000544 162.0
SRD2_k127_2512493_43 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000001078 176.0
SRD2_k127_2512493_44 phenylacetic acid degradation protein K02614 - - 0.00000000000000000000000000000000000000001184 163.0
SRD2_k127_2512493_45 Phenylacetic acid degradation K02610 - - 0.0000000000000000000000000000000000000282 158.0
SRD2_k127_2512493_46 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000001714 123.0
SRD2_k127_2512493_47 Small Multidrug Resistance protein - - - 0.00000000000000000000000002022 112.0
SRD2_k127_2512493_48 protein conserved in bacteria - - - 0.0000000000000000000009911 102.0
SRD2_k127_2512493_49 - - - - 0.000000000000004003 86.0
SRD2_k127_2512493_5 peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 583.0
SRD2_k127_2512493_50 peptidyl-tyrosine sulfation - - - 0.0000003674 61.0
SRD2_k127_2512493_51 NERD domain protein - - - 0.00001069 55.0
SRD2_k127_2512493_6 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 537.0
SRD2_k127_2512493_7 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 524.0
SRD2_k127_2512493_8 Phenylacetate-CoA oxygenase K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 513.0
SRD2_k127_2512493_9 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 492.0
SRD2_k127_2531664_0 DEAD DEAH box helicase K03724 - - 0.0 1948.0
SRD2_k127_2531664_1 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1235.0
SRD2_k127_2531664_10 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 494.0
SRD2_k127_2531664_11 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 459.0
SRD2_k127_2531664_12 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 449.0
SRD2_k127_2531664_13 Aminotransferase class I and II K00813,K00832 - 2.6.1.1,2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 437.0
SRD2_k127_2531664_14 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 427.0
SRD2_k127_2531664_15 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 420.0
SRD2_k127_2531664_16 (SAM)-dependent K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 420.0
SRD2_k127_2531664_17 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 391.0
SRD2_k127_2531664_18 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 372.0
SRD2_k127_2531664_19 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 392.0
SRD2_k127_2531664_2 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 3.351e-307 983.0
SRD2_k127_2531664_20 Belongs to the SUA5 family K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 372.0
SRD2_k127_2531664_21 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 363.0
SRD2_k127_2531664_22 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 356.0
SRD2_k127_2531664_23 Transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 346.0
SRD2_k127_2531664_24 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 317.0
SRD2_k127_2531664_25 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 305.0
SRD2_k127_2531664_26 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001894 277.0
SRD2_k127_2531664_27 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000011 267.0
SRD2_k127_2531664_28 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003991 264.0
SRD2_k127_2531664_29 Polypeptide deformylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002048 241.0
SRD2_k127_2531664_3 Protein of unknown function, DUF255 K06888 - - 4.961e-265 832.0
SRD2_k127_2531664_30 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000000000000000000000004734 239.0
SRD2_k127_2531664_31 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000006899 239.0
SRD2_k127_2531664_32 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000008894 234.0
SRD2_k127_2531664_33 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000001295 224.0
SRD2_k127_2531664_34 arylformamidase activity - - - 0.0000000000000000000000000000000000000000000000000000001696 203.0
SRD2_k127_2531664_35 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287,K18590 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000003068 198.0
SRD2_k127_2531664_36 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000004364 201.0
SRD2_k127_2531664_37 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000000000000001156 184.0
SRD2_k127_2531664_38 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000003924 181.0
SRD2_k127_2531664_39 PFAM ApaG domain protein K06195 - - 0.0000000000000000000000000000000000000000000001992 168.0
SRD2_k127_2531664_4 PDZ-like domain - - - 3.198e-251 816.0
SRD2_k127_2531664_40 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K01802,K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000003599 179.0
SRD2_k127_2531664_41 Protein of unknown function (DUF3224) - - - 0.0000000000000000000000000000000000000000000006771 169.0
SRD2_k127_2531664_42 virion core protein, lumpy skin disease virus - - - 0.00000000000000000000000000000000000000000004227 168.0
SRD2_k127_2531664_43 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000000000000000000000000002746 166.0
SRD2_k127_2531664_44 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000000000000000000000000000000001748 160.0
SRD2_k127_2531664_45 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000001463 132.0
SRD2_k127_2531664_46 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000003485 112.0
SRD2_k127_2531664_47 coenzyme PQQ synthesis K06138 - - 0.0000000000000000000000006942 117.0
SRD2_k127_2531664_48 HaD-superfamily hydrolase, subfamily ia, variant 3 K07025,K20866 - 3.1.3.10 0.000000000000007354 83.0
SRD2_k127_2531664_49 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000002106 78.0
SRD2_k127_2531664_5 Amidohydrolase family - - - 6.807e-213 679.0
SRD2_k127_2531664_51 Protein of unknown function (DUF2845) - - - 0.0001912 48.0
SRD2_k127_2531664_6 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 2.717e-202 643.0
SRD2_k127_2531664_7 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 555.0
SRD2_k127_2531664_8 Belongs to the radical SAM superfamily. PqqE family K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 533.0
SRD2_k127_2531664_9 Transport of potassium into the cell K03549 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 531.0
SRD2_k127_2602991_0 Sortilin, neurotensin receptor 3, - - - 0.0 1218.0
SRD2_k127_2602991_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 582.0
SRD2_k127_2602991_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 510.0
SRD2_k127_2602991_3 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 391.0
SRD2_k127_2602991_4 TonB-dependent receptor plug - - - 0.00000000000000000000000000000000000000002291 166.0
SRD2_k127_2602991_5 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000006976 96.0
SRD2_k127_2602991_6 - - - - 0.000001396 62.0
SRD2_k127_280181_0 Malonate decarboxylase K13929 - 2.3.1.187 3.216e-289 895.0
SRD2_k127_280181_1 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.528e-207 679.0
SRD2_k127_280181_10 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 404.0
SRD2_k127_280181_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 405.0
SRD2_k127_280181_12 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 404.0
SRD2_k127_280181_13 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 392.0
SRD2_k127_280181_14 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 397.0
SRD2_k127_280181_15 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 393.0
SRD2_k127_280181_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 381.0
SRD2_k127_280181_17 FMN-dependent dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 374.0
SRD2_k127_280181_18 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 361.0
SRD2_k127_280181_19 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 370.0
SRD2_k127_280181_2 Aminotransferase class-V K00830,K03430 - 2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 2.646e-207 650.0
SRD2_k127_280181_20 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 364.0
SRD2_k127_280181_21 Malonate decarboxylase K13933 - 4.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 361.0
SRD2_k127_280181_22 Zinc-binding dehydrogenase K00001,K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 363.0
SRD2_k127_280181_23 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 345.0
SRD2_k127_280181_24 ATP:dephospho-CoA triphosphoribosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 334.0
SRD2_k127_280181_25 Acyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 312.0
SRD2_k127_280181_26 PKHD-type hydroxylase K07336 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001489 276.0
SRD2_k127_280181_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002558 259.0
SRD2_k127_280181_28 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002385 243.0
SRD2_k127_280181_29 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002138 241.0
SRD2_k127_280181_3 COG1629 Outer membrane receptor proteins, mostly Fe transport K16090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 592.0
SRD2_k127_280181_30 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000001022 227.0
SRD2_k127_280181_31 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000002735 224.0
SRD2_k127_280181_32 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000004487 195.0
SRD2_k127_280181_33 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000008511 179.0
SRD2_k127_280181_34 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000002909 169.0
SRD2_k127_280181_35 Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism K13931 - - 0.000000000000000000000000000000000000000001022 161.0
SRD2_k127_280181_36 Phosphoribosyl-dephospho-CoA transferase MdcG - - - 0.00000000000000000000000000000000000000003016 162.0
SRD2_k127_280181_37 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000001253 151.0
SRD2_k127_280181_38 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000000004432 136.0
SRD2_k127_280181_39 - - - - 0.0000000000000000000000000000000007734 137.0
SRD2_k127_280181_4 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 576.0
SRD2_k127_280181_40 - - - - 0.000000000000000000000000000001272 128.0
SRD2_k127_280181_41 PFAM Cell wall hydrolase - - - 0.000000000000000000000000000007588 128.0
SRD2_k127_280181_42 Dodecin K09165 - - 0.00000000000000000000001213 103.0
SRD2_k127_280181_43 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.0000000000000000017 93.0
SRD2_k127_280181_44 - - - - 0.000000000000002843 82.0
SRD2_k127_280181_45 Membrane - - - 0.0000000002228 71.0
SRD2_k127_280181_46 - - - - 0.00006212 48.0
SRD2_k127_280181_47 Ankyrin repeats (many copies) K06867 - - 0.00009515 55.0
SRD2_k127_280181_48 - - - - 0.0002511 49.0
SRD2_k127_280181_49 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0006452 52.0
SRD2_k127_280181_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 558.0
SRD2_k127_280181_50 SMART Transport-associated and nodulation - - - 0.0006794 49.0
SRD2_k127_280181_6 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 548.0
SRD2_k127_280181_7 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 489.0
SRD2_k127_280181_8 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 473.0
SRD2_k127_280181_9 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 445.0
SRD2_k127_2875812_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 587.0
SRD2_k127_2875812_1 PFAM heat shock protein DnaJ domain protein K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 359.0
SRD2_k127_2875812_10 sporulation - - - 0.0000000211 65.0
SRD2_k127_2875812_11 Polymer-forming cytoskeletal - - - 0.0000002308 58.0
SRD2_k127_2875812_12 lyase activity - - - 0.0006116 51.0
SRD2_k127_2875812_2 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 324.0
SRD2_k127_2875812_3 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 307.0
SRD2_k127_2875812_4 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 295.0
SRD2_k127_2875812_5 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000002094 237.0
SRD2_k127_2875812_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000008818 187.0
SRD2_k127_2875812_7 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000000000000000006391 116.0
SRD2_k127_2875812_8 MerR HTH family regulatory protein K18997 - - 0.00000000000001151 83.0
SRD2_k127_2875812_9 Glycosyltransferase Family 4 K00786 - - 0.000000002296 62.0
SRD2_k127_2938015_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 424.0
SRD2_k127_2938015_1 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003436 284.0
SRD2_k127_2938015_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008805 269.0
SRD2_k127_2938015_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000002116 227.0
SRD2_k127_2938015_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000003917 185.0
SRD2_k127_2938015_5 protein conserved in bacteria K09928 - - 0.00000000000000000000000000000000003792 145.0
SRD2_k127_2938015_6 biopolymer transport protein K03559 - - 0.0000000000000000000000000003351 118.0
SRD2_k127_2978717_0 Acyl-CoA dehydrogenase N terminal K20035 - - 8.369e-197 630.0
SRD2_k127_2978717_1 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 473.0
SRD2_k127_2978717_10 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000853 243.0
SRD2_k127_2978717_11 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000005629 236.0
SRD2_k127_2978717_12 Periplasmic binding protein K02016,K06858 - - 0.0000000000000000000000000000000000000000000000000000000000001554 224.0
SRD2_k127_2978717_13 Thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000006844 215.0
SRD2_k127_2978717_14 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000009541 218.0
SRD2_k127_2978717_15 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000009505 203.0
SRD2_k127_2978717_16 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000002837 196.0
SRD2_k127_2978717_17 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000239 209.0
SRD2_k127_2978717_18 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.000000000000000000000000000000000000000000000000001033 188.0
SRD2_k127_2978717_19 Transcriptional regulator - - - 0.000000000000000000000000000000000000000004991 167.0
SRD2_k127_2978717_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 471.0
SRD2_k127_2978717_20 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000004922 156.0
SRD2_k127_2978717_21 Chalcone isomerase-like - - - 0.00000000000000000000000000000000002477 142.0
SRD2_k127_2978717_22 pilin assembly protein - - - 0.000000000000000000000000000000001503 134.0
SRD2_k127_2978717_23 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000007777 120.0
SRD2_k127_2978717_24 Lipocalin-like domain - - - 0.000000000000000000000000001562 121.0
SRD2_k127_2978717_25 CHAT domain - - - 0.0000000000000000000000004311 119.0
SRD2_k127_2978717_26 Protein conserved in bacteria K09796 - - 0.00000000000000000004139 96.0
SRD2_k127_2978717_27 Histidine kinase K08082 - 2.7.13.3 0.0000000000003928 74.0
SRD2_k127_2978717_28 domain protein K03320 - - 0.000000003332 70.0
SRD2_k127_2978717_3 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 391.0
SRD2_k127_2978717_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 345.0
SRD2_k127_2978717_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 304.0
SRD2_k127_2978717_6 Transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 301.0
SRD2_k127_2978717_7 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 285.0
SRD2_k127_2978717_8 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000003005 247.0
SRD2_k127_2978717_9 Na -driven multidrug efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000001031 242.0
SRD2_k127_2996675_0 FAD dependent oxidoreductase central domain - - - 0.0 1198.0
SRD2_k127_2996675_1 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.0 1198.0
SRD2_k127_2996675_10 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 421.0
SRD2_k127_2996675_11 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 392.0
SRD2_k127_2996675_12 oxidoreductase FAD NAD(P)-binding K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 354.0
SRD2_k127_2996675_13 Pfam:Transaldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 353.0
SRD2_k127_2996675_14 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 319.0
SRD2_k127_2996675_15 PFAM YkuD domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 304.0
SRD2_k127_2996675_16 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006173 278.0
SRD2_k127_2996675_17 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000003025 222.0
SRD2_k127_2996675_18 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000005469 214.0
SRD2_k127_2996675_19 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000007951 215.0
SRD2_k127_2996675_2 FAD dependent oxidoreductase central domain - - - 6.126e-304 952.0
SRD2_k127_2996675_20 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000001576 213.0
SRD2_k127_2996675_21 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000000000000000000000000000008351 206.0
SRD2_k127_2996675_22 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000001072 196.0
SRD2_k127_2996675_23 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000001856 183.0
SRD2_k127_2996675_24 E3 Ubiquitin ligase - - - 0.00000000000000000000000000000000000000000006719 172.0
SRD2_k127_2996675_25 FCD - - - 0.000000000000000000000000000000000000001414 157.0
SRD2_k127_2996675_26 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000001639 165.0
SRD2_k127_2996675_27 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000001749 153.0
SRD2_k127_2996675_28 cystathionine K01739 - 2.5.1.48 0.00000000000000001193 85.0
SRD2_k127_2996675_29 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000001638 89.0
SRD2_k127_2996675_3 Belongs to the Orn Lys Arg decarboxylase class-II family K00928,K12526 - 2.7.2.4,4.1.1.20 2.064e-296 932.0
SRD2_k127_2996675_30 Bacterial protein of unknown function (DUF883) - - - 0.00000000001561 69.0
SRD2_k127_2996675_31 Tetratricopeptide repeat - - - 0.00000000017 71.0
SRD2_k127_2996675_32 - - - - 0.0000000006938 72.0
SRD2_k127_2996675_34 membrane - - - 0.00002057 55.0
SRD2_k127_2996675_4 Carboxyl transferase domain K01969 - 6.4.1.4 9.487e-243 781.0
SRD2_k127_2996675_5 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 8.794e-206 666.0
SRD2_k127_2996675_6 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 2.326e-196 629.0
SRD2_k127_2996675_7 dehydrogenase K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 552.0
SRD2_k127_2996675_8 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 556.0
SRD2_k127_2996675_9 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 458.0
SRD2_k127_2999224_0 prolyl oligopeptidase K01322 - 3.4.21.26 1.733e-202 654.0
SRD2_k127_2999224_1 Coenzyme F420-reducing hydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 591.0
SRD2_k127_2999224_10 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 370.0
SRD2_k127_2999224_11 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 355.0
SRD2_k127_2999224_12 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 327.0
SRD2_k127_2999224_13 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 308.0
SRD2_k127_2999224_14 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 - 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 297.0
SRD2_k127_2999224_15 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 291.0
SRD2_k127_2999224_16 PFAM Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001706 297.0
SRD2_k127_2999224_17 peptidoglycan-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009723 278.0
SRD2_k127_2999224_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000001333 285.0
SRD2_k127_2999224_19 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007479 254.0
SRD2_k127_2999224_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 575.0
SRD2_k127_2999224_20 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001405 267.0
SRD2_k127_2999224_21 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000002372 254.0
SRD2_k127_2999224_22 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001272 231.0
SRD2_k127_2999224_23 helix_turn_helix, Lux Regulon K02479 - - 0.000000000000000000000000000000000000000000000000000000000003054 219.0
SRD2_k127_2999224_24 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000001201 217.0
SRD2_k127_2999224_25 alpha beta - - - 0.000000000000000000000000000000000000000000000000001679 187.0
SRD2_k127_2999224_26 - - - - 0.000000000000000000000000000000000000000000000003706 178.0
SRD2_k127_2999224_27 Ketosteroid isomerase-related protein - - - 0.0000000000000000000000000000000000000000006689 159.0
SRD2_k127_2999224_28 PFAM Abortive infection protein K07052 - - 0.000000000000000000000000000000000000002268 155.0
SRD2_k127_2999224_29 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000003219 148.0
SRD2_k127_2999224_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 464.0
SRD2_k127_2999224_30 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000004401 149.0
SRD2_k127_2999224_31 Phage integrase family - - - 0.0000000000000000000000000000000000001118 147.0
SRD2_k127_2999224_33 - - - - 0.0000000000000000000000000000003836 134.0
SRD2_k127_2999224_34 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000008112 134.0
SRD2_k127_2999224_35 Rhodanese Homology Domain - - - 0.000000000000000000000000001082 116.0
SRD2_k127_2999224_37 PhoQ Sensor - - - 0.0000000000000000000000005335 120.0
SRD2_k127_2999224_38 PAS domain K07315 - 3.1.3.3 0.0000000000000000000000184 117.0
SRD2_k127_2999224_39 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K01749,K02303,K13542,K13543 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.0000000000000000002399 100.0
SRD2_k127_2999224_4 permease K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 458.0
SRD2_k127_2999224_40 aldo keto reductase K05275 - 1.1.1.65 0.000000000000001015 78.0
SRD2_k127_2999224_41 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000002753 82.0
SRD2_k127_2999224_42 - - - - 0.0000000000002345 81.0
SRD2_k127_2999224_43 ORF6N domain - - - 0.0000000002082 62.0
SRD2_k127_2999224_45 Transcriptional regulatory protein, C terminal - - - 0.00001213 51.0
SRD2_k127_2999224_46 - - - - 0.0001961 51.0
SRD2_k127_2999224_5 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 448.0
SRD2_k127_2999224_6 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 448.0
SRD2_k127_2999224_7 abc transporter atp-binding protein K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 404.0
SRD2_k127_2999224_8 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 391.0
SRD2_k127_2999224_9 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 382.0
SRD2_k127_3057228_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1420.0
SRD2_k127_3057228_1 DNA ligase K01971 - 6.5.1.1 0.0 1081.0
SRD2_k127_3057228_10 Bacterial protein of unknown function (DUF885) - - - 4.263e-243 765.0
SRD2_k127_3057228_100 Isochorismatase family K13995 - 3.5.1.107 0.0000000000000000000000000000000000000000000000000000000001474 212.0
SRD2_k127_3057228_101 ADP-ribose pyrophosphatase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000005429 209.0
SRD2_k127_3057228_102 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000005432 207.0
SRD2_k127_3057228_103 - - - - 0.00000000000000000000000000000000000000000000000000000002315 212.0
SRD2_k127_3057228_104 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000003411 200.0
SRD2_k127_3057228_105 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000009562 198.0
SRD2_k127_3057228_106 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000002015 200.0
SRD2_k127_3057228_107 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000005314 199.0
SRD2_k127_3057228_109 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000004845 195.0
SRD2_k127_3057228_11 Alpha-amylase domain K01187 - 3.2.1.20 1.82e-242 764.0
SRD2_k127_3057228_110 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000005858 196.0
SRD2_k127_3057228_111 radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000005895 195.0
SRD2_k127_3057228_112 PFAM 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.00000000000000000000000000000000000000000000000000009879 188.0
SRD2_k127_3057228_113 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000004129 195.0
SRD2_k127_3057228_114 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000000000003081 184.0
SRD2_k127_3057228_115 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000001313 191.0
SRD2_k127_3057228_116 FCD - - - 0.000000000000000000000000000000000000000000000001566 182.0
SRD2_k127_3057228_117 NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000005886 176.0
SRD2_k127_3057228_118 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000004253 177.0
SRD2_k127_3057228_119 conserved protein UCP033924 - - - 0.00000000000000000000000000000000000000000000009285 172.0
SRD2_k127_3057228_12 Alpha-amylase domain K01187 - 3.2.1.20 6.621e-237 745.0
SRD2_k127_3057228_120 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000001006 180.0
SRD2_k127_3057228_121 PFAM EAL domain, GGDEF domain - - - 0.00000000000000000000000000000000000000000002287 174.0
SRD2_k127_3057228_122 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000001253 177.0
SRD2_k127_3057228_123 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000002171 159.0
SRD2_k127_3057228_124 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000001299 156.0
SRD2_k127_3057228_125 homoprotocatechuate degradation operon regulator, HpaR - - - 0.000000000000000000000000000000000000001524 153.0
SRD2_k127_3057228_126 PFAM Extradiol ring-cleavage dioxygenase LigAB LigA subunit - - - 0.00000000000000000000000000000000000001251 147.0
SRD2_k127_3057228_127 cellulase activity - - - 0.00000000000000000000000000000000000004602 156.0
SRD2_k127_3057228_128 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000002146 150.0
SRD2_k127_3057228_129 Invasion gene expression up-regulator, SirB - - - 0.00000000000000000000000000000000001101 140.0
SRD2_k127_3057228_13 Belongs to the purine-cytosine permease (2.A.39) family K03457 - - 5.676e-223 699.0
SRD2_k127_3057228_130 PFAM Cytochrome C - - - 0.0000000000000000000000000000000004915 141.0
SRD2_k127_3057228_131 PFAM phosphoesterase K01114 - 3.1.4.3 0.000000000000000000000000000000006082 131.0
SRD2_k127_3057228_132 EthD domain - - - 0.0000000000000000000000000000007633 124.0
SRD2_k127_3057228_133 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000000832 122.0
SRD2_k127_3057228_134 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000008275 116.0
SRD2_k127_3057228_135 Protein of unknown function (DUF861) - - - 0.0000000000000000000000000001274 119.0
SRD2_k127_3057228_136 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000324 122.0
SRD2_k127_3057228_137 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000000006335 128.0
SRD2_k127_3057228_139 Cytochrome c - - - 0.0000000000000000000000001148 113.0
SRD2_k127_3057228_14 PFAM Pyridoxal-dependent decarboxylase - - - 5.973e-220 691.0
SRD2_k127_3057228_140 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000001736 113.0
SRD2_k127_3057228_141 - - - - 0.000000000000000000000000331 114.0
SRD2_k127_3057228_142 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000003952 113.0
SRD2_k127_3057228_143 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000007969 106.0
SRD2_k127_3057228_144 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000004951 91.0
SRD2_k127_3057228_145 OmpA family - - - 0.00000000000000000005747 99.0
SRD2_k127_3057228_146 - - - - 0.0000000000000000000597 93.0
SRD2_k127_3057228_147 DUF167 K09131 - - 0.0000000000000000000819 94.0
SRD2_k127_3057228_148 - - - - 0.0000000000000000001501 93.0
SRD2_k127_3057228_149 Protein of unknown function (DUF2905) - - - 0.0000000000000000004187 88.0
SRD2_k127_3057228_15 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 1.002e-218 707.0
SRD2_k127_3057228_150 Transcriptional regulator - - - 0.000000000000000004031 88.0
SRD2_k127_3057228_152 - - - - 0.00000000000005403 75.0
SRD2_k127_3057228_153 Ammonia monooxygenase K07120 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000007101 74.0
SRD2_k127_3057228_154 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000001285 77.0
SRD2_k127_3057228_155 tail collar domain protein - - - 0.0000000000002498 84.0
SRD2_k127_3057228_157 - - - - 0.00000000006242 76.0
SRD2_k127_3057228_158 Diguanylate cyclase K21021 - 2.7.7.65 0.0000000002482 68.0
SRD2_k127_3057228_159 Domain of unknown function (DUF4279) - - - 0.0000000003086 67.0
SRD2_k127_3057228_16 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 9.327e-218 686.0
SRD2_k127_3057228_160 - - - - 0.000000002486 64.0
SRD2_k127_3057228_161 PFAM Metal-dependent hydrolase HDOD - - - 0.000000005381 66.0
SRD2_k127_3057228_162 Poly (ADP-ribose) polymerase K10798 GO:0001101,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006464,GO:0006471,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009719,GO:0009725,GO:0009737,GO:0009987,GO:0010033,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0019538,GO:0022616,GO:0033554,GO:0033993,GO:0034641,GO:0034645,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0097305,GO:0140097,GO:1901360,GO:1901564,GO:1901576,GO:1901700 2.4.2.30 0.000004765 56.0
SRD2_k127_3057228_163 Protein of unknown function (DUF3052) - - - 0.000005131 57.0
SRD2_k127_3057228_164 - - - - 0.000008518 54.0
SRD2_k127_3057228_167 Gram-negative bacterial TonB protein C-terminal - - - 0.0004649 49.0
SRD2_k127_3057228_17 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.776e-217 692.0
SRD2_k127_3057228_18 Isocitrate dehydrogenase - - - 2.528e-217 681.0
SRD2_k127_3057228_19 Outer membrane receptor proteins mostly Fe transport - - - 2.2e-208 683.0
SRD2_k127_3057228_2 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 6.659e-313 974.0
SRD2_k127_3057228_20 Major facilitator superfamily K16211 - - 4.898e-207 654.0
SRD2_k127_3057228_21 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 1.196e-200 653.0
SRD2_k127_3057228_22 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 2.27e-200 633.0
SRD2_k127_3057228_23 Glucose dehydrogenase - - - 5.216e-196 632.0
SRD2_k127_3057228_24 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.297e-195 617.0
SRD2_k127_3057228_25 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 614.0
SRD2_k127_3057228_26 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 628.0
SRD2_k127_3057228_27 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 610.0
SRD2_k127_3057228_28 Cardiolipin synthase K06132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 591.0
SRD2_k127_3057228_29 FAD dependent oxidoreductase K00316 - 1.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 563.0
SRD2_k127_3057228_3 PFAM peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 3.083e-308 977.0
SRD2_k127_3057228_30 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 561.0
SRD2_k127_3057228_31 Major facilitator superfamily K08178 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 550.0
SRD2_k127_3057228_32 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 535.0
SRD2_k127_3057228_33 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 542.0
SRD2_k127_3057228_34 UPF0210 protein K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 522.0
SRD2_k127_3057228_35 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 509.0
SRD2_k127_3057228_36 PFAM Rieske 2Fe-2S domain protein K18068 - 1.14.12.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 508.0
SRD2_k127_3057228_37 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 499.0
SRD2_k127_3057228_38 FAD dependent oxidoreductase K09471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 483.0
SRD2_k127_3057228_39 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 479.0
SRD2_k127_3057228_4 Multicopper oxidase K00368 - 1.7.2.1 9.999e-285 885.0
SRD2_k127_3057228_40 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 486.0
SRD2_k127_3057228_41 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 496.0
SRD2_k127_3057228_42 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 492.0
SRD2_k127_3057228_43 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 464.0
SRD2_k127_3057228_44 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 492.0
SRD2_k127_3057228_45 Periplasmic binding protein domain K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 438.0
SRD2_k127_3057228_46 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04101,K05713 - 1.13.11.16,1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 446.0
SRD2_k127_3057228_47 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 431.0
SRD2_k127_3057228_48 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 424.0
SRD2_k127_3057228_49 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 437.0
SRD2_k127_3057228_5 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 6.24e-283 885.0
SRD2_k127_3057228_50 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 426.0
SRD2_k127_3057228_51 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 401.0
SRD2_k127_3057228_52 Fumarylacetoacetate (FAA) hydrolase family K02509,K18364 - 4.2.1.132,4.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 389.0
SRD2_k127_3057228_53 4-hydroxyphenylacetate degradation bifunctional isomerase K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 389.0
SRD2_k127_3057228_54 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 389.0
SRD2_k127_3057228_55 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 394.0
SRD2_k127_3057228_56 PFAM Pyruvate carboxyltransferase K01640,K18314 - 4.1.3.4,4.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 383.0
SRD2_k127_3057228_57 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 396.0
SRD2_k127_3057228_58 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 373.0
SRD2_k127_3057228_59 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 377.0
SRD2_k127_3057228_6 Thiamine pyrophosphate enzyme, central domain K01577 - 4.1.1.8 7.776e-270 842.0
SRD2_k127_3057228_60 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 363.0
SRD2_k127_3057228_61 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 370.0
SRD2_k127_3057228_62 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 351.0
SRD2_k127_3057228_63 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 355.0
SRD2_k127_3057228_64 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 344.0
SRD2_k127_3057228_65 Putrescine transport system permease K11075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 354.0
SRD2_k127_3057228_66 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 338.0
SRD2_k127_3057228_67 peptidase M19 K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 340.0
SRD2_k127_3057228_68 COG1177 ABC-type spermidine putrescine transport system, permease component II K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 332.0
SRD2_k127_3057228_69 Prolyl oligopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 347.0
SRD2_k127_3057228_7 Alpha-amylase domain - - - 1.046e-268 850.0
SRD2_k127_3057228_70 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 330.0
SRD2_k127_3057228_71 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 324.0
SRD2_k127_3057228_72 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 325.0
SRD2_k127_3057228_73 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 325.0
SRD2_k127_3057228_74 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 319.0
SRD2_k127_3057228_75 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 321.0
SRD2_k127_3057228_76 PFAM lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 307.0
SRD2_k127_3057228_77 carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 296.0
SRD2_k127_3057228_78 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 296.0
SRD2_k127_3057228_79 PFAM Acetamidase Formamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 305.0
SRD2_k127_3057228_8 belongs to the aldehyde dehydrogenase family K00151 - 1.2.1.60 7.391e-264 818.0
SRD2_k127_3057228_80 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001202 286.0
SRD2_k127_3057228_81 PFAM class II aldolase adducin family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007044 285.0
SRD2_k127_3057228_82 Protein of unknown function (DUF1348) K09958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001265 278.0
SRD2_k127_3057228_83 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001185 285.0
SRD2_k127_3057228_84 Major Facilitator Superfamily K02445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001226 279.0
SRD2_k127_3057228_85 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004761 269.0
SRD2_k127_3057228_86 PFAM Cys Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000004617 276.0
SRD2_k127_3057228_87 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000001063 267.0
SRD2_k127_3057228_88 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 266.0
SRD2_k127_3057228_89 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005088 266.0
SRD2_k127_3057228_9 Belongs to the peptidase M16 family K07263 - - 9.321e-261 845.0
SRD2_k127_3057228_90 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000001027 252.0
SRD2_k127_3057228_91 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002382 251.0
SRD2_k127_3057228_92 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003141 255.0
SRD2_k127_3057228_93 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001131 253.0
SRD2_k127_3057228_94 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000002172 237.0
SRD2_k127_3057228_95 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001138 232.0
SRD2_k127_3057228_96 Methylamine dehydrogenase light chain K15228 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000005068 223.0
SRD2_k127_3057228_97 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000389 218.0
SRD2_k127_3057228_99 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000168 220.0
SRD2_k127_3058518_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 5.716e-257 808.0
SRD2_k127_3058518_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.67e-220 692.0
SRD2_k127_3058518_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002832 261.0
SRD2_k127_3058518_11 YXWGXW repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004212 262.0
SRD2_k127_3058518_12 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000001215 217.0
SRD2_k127_3058518_13 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000002029 216.0
SRD2_k127_3058518_14 Iron-sulphur cluster biosynthesis K05997,K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0019538,GO:0022607,GO:0031163,GO:0034986,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901564 - 0.000000000000000000000000000000000000001772 149.0
SRD2_k127_3058518_15 type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000004482 159.0
SRD2_k127_3058518_16 protein conserved in bacteria - - - 0.0000000000000000000000000001056 125.0
SRD2_k127_3058518_17 protein conserved in bacteria K15539 - - 0.000000000000001058 91.0
SRD2_k127_3058518_18 C-terminus of AA_permease K03294 - - 0.000000000000006477 77.0
SRD2_k127_3058518_2 trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 604.0
SRD2_k127_3058518_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 512.0
SRD2_k127_3058518_4 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 511.0
SRD2_k127_3058518_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 486.0
SRD2_k127_3058518_6 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 438.0
SRD2_k127_3058518_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 423.0
SRD2_k127_3058518_8 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 415.0
SRD2_k127_3058518_9 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 331.0
SRD2_k127_3064268_0 Elongation factor SelB, winged helix K03833 - - 8.909e-223 708.0
SRD2_k127_3064268_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 8.987e-200 649.0
SRD2_k127_3064268_10 Histidine kinase K07637 - 2.7.13.3 0.000000000004625 66.0
SRD2_k127_3064268_11 Belongs to the SAICAR synthetase family K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000002395 51.0
SRD2_k127_3064268_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 3.193e-197 634.0
SRD2_k127_3064268_3 Isocitrate K00031 GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114 1.1.1.42 7.484e-196 619.0
SRD2_k127_3064268_4 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 605.0
SRD2_k127_3064268_5 Selenocysteine synthase N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 576.0
SRD2_k127_3064268_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 487.0
SRD2_k127_3064268_7 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 443.0
SRD2_k127_3064268_8 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 266.0
SRD2_k127_3064268_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000002649 219.0
SRD2_k127_3096997_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 4.611e-278 870.0
SRD2_k127_3096997_1 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 416.0
SRD2_k127_3096997_10 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009532 250.0
SRD2_k127_3096997_11 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001711 237.0
SRD2_k127_3096997_12 Role in flagellar biosynthesis K02421 - - 0.00000000000000000000000000000000000000000000000000000000006991 213.0
SRD2_k127_3096997_13 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.0000000000000000000000000000000000000000000003639 168.0
SRD2_k127_3096997_14 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000000000000000001444 166.0
SRD2_k127_3096997_15 HDOD domain - - - 0.00000000000000000000000000000000000000000001822 173.0
SRD2_k127_3096997_16 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000001674 170.0
SRD2_k127_3096997_17 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000000000000000177 139.0
SRD2_k127_3096997_18 Role in flagellar biosynthesis K02420 - - 0.00000000000000000000000000003777 118.0
SRD2_k127_3096997_19 Flagellar basal body-associated protein FliL - - - 0.0000000000000000000000000707 114.0
SRD2_k127_3096997_2 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 328.0
SRD2_k127_3096997_20 thiolester hydrolase activity K06889 - - 0.000000000000000000000002057 117.0
SRD2_k127_3096997_21 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.000000000000000000005722 103.0
SRD2_k127_3096997_22 PFAM Flagellar hook-length control protein K02414 - - 0.00000000000000005335 94.0
SRD2_k127_3096997_23 Flagellar biosynthesis protein, FliO K02418 - - 0.00000000000000008817 84.0
SRD2_k127_3096997_24 - - - - 0.0000000000002041 78.0
SRD2_k127_3096997_25 Flagellar FliJ protein K02413 - - 0.0000005211 57.0
SRD2_k127_3096997_26 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000005756 52.0
SRD2_k127_3096997_27 chemotaxis, protein - - - 0.00006468 51.0
SRD2_k127_3096997_28 PFAM Anti-sigma-28 factor FlgM family protein K02398 - - 0.00007343 53.0
SRD2_k127_3096997_29 FlgN protein K02399 - - 0.0001281 50.0
SRD2_k127_3096997_3 this protein with a related protein (a MotB homolog) forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 316.0
SRD2_k127_3096997_4 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 308.0
SRD2_k127_3096997_5 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 292.0
SRD2_k127_3096997_6 flagellar K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004541 292.0
SRD2_k127_3096997_7 Flagellar motor protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001916 278.0
SRD2_k127_3096997_8 ATPase FliI YscN family K02412 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000001598 261.0
SRD2_k127_3096997_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008693 256.0
SRD2_k127_3110354_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 623.0
SRD2_k127_3110354_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 528.0
SRD2_k127_3110354_10 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000101 195.0
SRD2_k127_3110354_11 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.00000000000000000000000000000000000000000000000000005062 190.0
SRD2_k127_3110354_12 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000001409 167.0
SRD2_k127_3110354_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000001434 132.0
SRD2_k127_3110354_14 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000003651 124.0
SRD2_k127_3110354_15 PDZ domain - - - 0.0000000000000000002328 100.0
SRD2_k127_3110354_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 492.0
SRD2_k127_3110354_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 392.0
SRD2_k127_3110354_4 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 382.0
SRD2_k127_3110354_5 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001215 278.0
SRD2_k127_3110354_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004623 271.0
SRD2_k127_3110354_7 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000009434 252.0
SRD2_k127_3110354_8 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000001253 237.0
SRD2_k127_3110354_9 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000001241 208.0
SRD2_k127_3154357_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 5.443e-198 624.0
SRD2_k127_3154357_1 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 422.0
SRD2_k127_3154357_2 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 359.0
SRD2_k127_3154357_3 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.000000000000000000000000000000000000000004892 169.0
SRD2_k127_3154357_4 Belongs to the BolA IbaG family - - - 0.00000000000001563 88.0
SRD2_k127_3154357_5 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0007466 49.0
SRD2_k127_3155513_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1311.0
SRD2_k127_3155513_1 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 1.55e-320 998.0
SRD2_k127_3155513_10 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000001621 251.0
SRD2_k127_3155513_11 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006265 239.0
SRD2_k127_3155513_12 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000005243 221.0
SRD2_k127_3155513_13 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000004303 205.0
SRD2_k127_3155513_14 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000008172 175.0
SRD2_k127_3155513_15 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000008475 149.0
SRD2_k127_3155513_16 - - - - 0.000000000000000000000000000000000002766 145.0
SRD2_k127_3155513_17 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000004449 138.0
SRD2_k127_3155513_18 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062,K18828 - - 0.0000000000000000000000000000000001611 136.0
SRD2_k127_3155513_19 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000004603 136.0
SRD2_k127_3155513_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 1.577e-207 666.0
SRD2_k127_3155513_20 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000003399 127.0
SRD2_k127_3155513_22 transcriptional - - - 0.0000000000000000000000023 106.0
SRD2_k127_3155513_23 Protein of unknown function (DUF2892) - - - 0.00000000000000000000003309 100.0
SRD2_k127_3155513_24 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.00000000000000000000004028 104.0
SRD2_k127_3155513_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 619.0
SRD2_k127_3155513_4 trisaccharide binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 574.0
SRD2_k127_3155513_5 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 556.0
SRD2_k127_3155513_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 344.0
SRD2_k127_3155513_7 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 311.0
SRD2_k127_3155513_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 302.0
SRD2_k127_3155513_9 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001712 271.0
SRD2_k127_3162816_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 407.0
SRD2_k127_3162816_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 366.0
SRD2_k127_3162816_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 - 0.000000000000000000000000000000000000000000000000000000004911 202.0
SRD2_k127_3162816_3 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000004219 172.0
SRD2_k127_3162816_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000001497 154.0
SRD2_k127_3191687_0 FAD dependent oxidoreductase central domain - - - 0.0 1290.0
SRD2_k127_3191687_1 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 1.145e-307 956.0
SRD2_k127_3191687_10 Serine hydrolase (FSH1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 600.0
SRD2_k127_3191687_11 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 583.0
SRD2_k127_3191687_12 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 592.0
SRD2_k127_3191687_13 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 563.0
SRD2_k127_3191687_14 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 483.0
SRD2_k127_3191687_15 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 497.0
SRD2_k127_3191687_16 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 437.0
SRD2_k127_3191687_17 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 436.0
SRD2_k127_3191687_18 Sulfotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 437.0
SRD2_k127_3191687_19 PFAM Cys Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 416.0
SRD2_k127_3191687_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 2.455e-289 895.0
SRD2_k127_3191687_20 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 385.0
SRD2_k127_3191687_21 receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 382.0
SRD2_k127_3191687_22 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 364.0
SRD2_k127_3191687_23 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 347.0
SRD2_k127_3191687_24 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002205 280.0
SRD2_k127_3191687_25 Histidine kinase K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000103 277.0
SRD2_k127_3191687_26 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001318 275.0
SRD2_k127_3191687_27 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001801 251.0
SRD2_k127_3191687_28 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000008953 242.0
SRD2_k127_3191687_29 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000000005902 162.0
SRD2_k127_3191687_3 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - 1.016e-266 836.0
SRD2_k127_3191687_30 PFAM Cytochrome C - - - 0.00000000000000000000000000000000000000004425 161.0
SRD2_k127_3191687_31 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000000004226 146.0
SRD2_k127_3191687_32 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000000000000000000000000004387 133.0
SRD2_k127_3191687_34 PFAM UspA domain protein K14055 GO:0000302,GO:0001539,GO:0006928,GO:0006950,GO:0006979,GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0033554,GO:0034599,GO:0034614,GO:0034644,GO:0035690,GO:0040011,GO:0042221,GO:0042493,GO:0042542,GO:0042710,GO:0044010,GO:0044764,GO:0046677,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071478,GO:0071482,GO:0071973,GO:0097237,GO:0097588,GO:0104004,GO:1901700,GO:1901701 - 0.000000000000000000000001017 115.0
SRD2_k127_3191687_35 PFAM CopG domain protein DNA-binding domain protein - - - 0.000000000000000003016 86.0
SRD2_k127_3191687_36 Domain of unknown function (DUF202) K00389 - - 0.0000000000001659 74.0
SRD2_k127_3191687_37 Protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 0.0000000001816 68.0
SRD2_k127_3191687_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 2.489e-254 795.0
SRD2_k127_3191687_5 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 2.075e-245 769.0
SRD2_k127_3191687_6 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K12141 - - 3.795e-244 764.0
SRD2_k127_3191687_7 Aldehyde dehydrogenase family K00294 - 1.2.1.88 3.729e-231 726.0
SRD2_k127_3191687_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 5.32e-210 659.0
SRD2_k127_3191687_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 613.0
SRD2_k127_3197631_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 557.0
SRD2_k127_3197631_1 - - - - 0.00000000000000000000000000000000006604 137.0
SRD2_k127_3197631_2 belongs to the nudix hydrolase family K03574 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.000000000000000000000000000000000106 141.0
SRD2_k127_3197631_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000005966 124.0
SRD2_k127_319841_0 Domain of unknown function (DUF5117) - - - 5.311e-317 995.0
SRD2_k127_319841_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.062e-314 972.0
SRD2_k127_319841_10 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 319.0
SRD2_k127_319841_11 PFAM aldo keto reductase - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 316.0
SRD2_k127_319841_12 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000111 277.0
SRD2_k127_319841_13 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006282 256.0
SRD2_k127_319841_14 Transcriptional regulator K05800 - - 0.00000000000000000000000000000000000000000000000000001003 195.0
SRD2_k127_319841_15 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000001525 203.0
SRD2_k127_319841_16 YCII-related domain - - - 0.000000000000000000000000000000000000000000000002261 178.0
SRD2_k127_319841_17 Repressor involved in choline regulation of the bet genes K02167 - - 0.00000000000000000000000000000000000000000000003623 187.0
SRD2_k127_319841_18 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000009645 114.0
SRD2_k127_319841_19 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000000000000001966 102.0
SRD2_k127_319841_2 ABC-type multidrug transport system ATPase and permease K06147 - - 1.01e-293 914.0
SRD2_k127_319841_20 - - - - 0.000000000000000000007248 100.0
SRD2_k127_319841_21 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000002461 81.0
SRD2_k127_319841_22 PilZ domain - - - 0.000000000003997 70.0
SRD2_k127_319841_23 - - - - 0.000000001966 58.0
SRD2_k127_319841_3 GTP-binding protein TypA K06207 - - 1.972e-285 888.0
SRD2_k127_319841_4 Thi4 family - - - 1.206e-256 803.0
SRD2_k127_319841_5 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 1.105e-205 646.0
SRD2_k127_319841_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 466.0
SRD2_k127_319841_7 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 404.0
SRD2_k127_319841_8 COG3547 Transposase and inactivated derivatives K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 394.0
SRD2_k127_319841_9 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 359.0
SRD2_k127_3203388_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 1.061e-287 899.0
SRD2_k127_3203388_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 8.207e-204 642.0
SRD2_k127_3203388_10 chemotaxis, protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 319.0
SRD2_k127_3203388_11 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 293.0
SRD2_k127_3203388_12 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 290.0
SRD2_k127_3203388_13 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001449 278.0
SRD2_k127_3203388_14 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002214 253.0
SRD2_k127_3203388_15 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000002393 207.0
SRD2_k127_3203388_16 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000009329 198.0
SRD2_k127_3203388_17 Ferritin-like domain - - - 0.0000000000000000000000000000000000000000000000000006903 187.0
SRD2_k127_3203388_18 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000005314 139.0
SRD2_k127_3203388_19 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000002247 133.0
SRD2_k127_3203388_2 Major Facilitator Superfamily - - - 9.278e-202 638.0
SRD2_k127_3203388_20 PFAM Cache, type 2 - - - 0.00000000000000000000000000000003915 131.0
SRD2_k127_3203388_21 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000007601 102.0
SRD2_k127_3203388_22 - - - - 0.00000000000000000000002307 106.0
SRD2_k127_3203388_23 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000007222 100.0
SRD2_k127_3203388_24 Polysaccharide lyase - - - 0.00000000000000008143 91.0
SRD2_k127_3203388_25 - - - - 0.000002746 49.0
SRD2_k127_3203388_26 Domain of unknown function (DUF4136) - - - 0.0006801 49.0
SRD2_k127_3203388_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 517.0
SRD2_k127_3203388_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 440.0
SRD2_k127_3203388_5 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 423.0
SRD2_k127_3203388_6 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 411.0
SRD2_k127_3203388_7 Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 392.0
SRD2_k127_3203388_8 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 361.0
SRD2_k127_3203388_9 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 323.0
SRD2_k127_3246557_0 Heat shock 70 kDa protein K04043 - - 2.075e-263 816.0
SRD2_k127_3246557_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 447.0
SRD2_k127_3246557_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 384.0
SRD2_k127_3246557_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000001217 261.0
SRD2_k127_3246557_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000004218 225.0
SRD2_k127_3246557_5 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000002901 214.0
SRD2_k127_3246557_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000001016 163.0
SRD2_k127_3246557_7 Cyclase dehydrase - - - 0.00000000000000000000000000000000001348 139.0
SRD2_k127_3246557_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000039 104.0
SRD2_k127_3246557_9 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000005376 72.0
SRD2_k127_3257803_0 MMPL family - - - 7.422e-204 666.0
SRD2_k127_3257803_1 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 520.0
SRD2_k127_3257803_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000003574 162.0
SRD2_k127_3257803_11 esterase - - - 0.0000000000000000000000000000000000000002671 172.0
SRD2_k127_3257803_12 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000000001171 125.0
SRD2_k127_3257803_13 AMP-binding enzyme - - - 0.0000000000000000003692 101.0
SRD2_k127_3257803_2 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 492.0
SRD2_k127_3257803_3 Glycosyltransferase like family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 374.0
SRD2_k127_3257803_4 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 330.0
SRD2_k127_3257803_5 Polysaccharide deacetylase K01452 - 3.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 320.0
SRD2_k127_3257803_6 MltA-interacting protein MipA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 318.0
SRD2_k127_3257803_7 pteridine-dependent deoxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 302.0
SRD2_k127_3257803_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004223 273.0
SRD2_k127_3257803_9 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008155 260.0
SRD2_k127_3271673_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 449.0
SRD2_k127_3271673_1 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 424.0
SRD2_k127_3271673_10 COG2202 FOG PAS PAC domain K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000001823 230.0
SRD2_k127_3271673_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001194 226.0
SRD2_k127_3271673_12 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000004648 225.0
SRD2_k127_3271673_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000009198 190.0
SRD2_k127_3271673_14 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000001251 169.0
SRD2_k127_3271673_15 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000959 162.0
SRD2_k127_3271673_16 PFAM flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000000002076 111.0
SRD2_k127_3271673_17 Atypical PilZ domain, cyclic di-GMP receptor - - - 0.00000000000000000004099 98.0
SRD2_k127_3271673_18 bacterial OsmY and nodulation domain - - - 0.000000005287 59.0
SRD2_k127_3271673_2 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 409.0
SRD2_k127_3271673_20 Flagellar protein FliS K02422 GO:0001539,GO:0003674,GO:0005198,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.0002345 49.0
SRD2_k127_3271673_3 Fis family transcriptional regulator K10941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 393.0
SRD2_k127_3271673_4 Two component, sigma54 specific, transcriptional regulator, Fis family K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 373.0
SRD2_k127_3271673_5 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 337.0
SRD2_k127_3271673_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 293.0
SRD2_k127_3271673_7 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 293.0
SRD2_k127_3271673_8 light absorption - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001661 263.0
SRD2_k127_3271673_9 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000006081 243.0
SRD2_k127_3336860_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.707e-290 913.0
SRD2_k127_3336860_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.134e-277 866.0
SRD2_k127_3336860_2 Participates in both transcription termination and antitermination K02600 - - 1.079e-220 693.0
SRD2_k127_3336860_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007068 278.0
SRD2_k127_3336860_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000004779 124.0
SRD2_k127_3336860_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000001964 114.0
SRD2_k127_3428369_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 8.095e-276 862.0
SRD2_k127_3428369_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 433.0
SRD2_k127_3428369_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000105 112.0
SRD2_k127_3428369_11 - - - - 0.0000000002816 67.0
SRD2_k127_3428369_2 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002789 267.0
SRD2_k127_3428369_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000004713 232.0
SRD2_k127_3428369_4 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000001835 220.0
SRD2_k127_3428369_5 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000000000000000000000000000000002855 224.0
SRD2_k127_3428369_6 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000006679 204.0
SRD2_k127_3428369_7 Thioesterase - - - 0.000000000000000000000000000000000000000001107 159.0
SRD2_k127_3428369_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000003649 155.0
SRD2_k127_3428369_9 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000009762 140.0
SRD2_k127_3448009_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 580.0
SRD2_k127_3448009_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 463.0
SRD2_k127_3448009_10 TIGRFAM Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.0000001829 62.0
SRD2_k127_3448009_2 alpha/beta hydrolase fold K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 345.0
SRD2_k127_3448009_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 320.0
SRD2_k127_3448009_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 305.0
SRD2_k127_3448009_5 synthesis repressor, PhaR - - - 0.0000000000000000000000000000000000003011 147.0
SRD2_k127_3448009_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.00000000000000000000000000000000001041 138.0
SRD2_k127_3448009_7 - - - - 0.00000000000000000000000004755 122.0
SRD2_k127_3448009_8 cAMP biosynthetic process - - - 0.000000000000000000009562 109.0
SRD2_k127_3448009_9 Histone deacetylation protein Rxt3 - - - 0.0000000000000004143 83.0
SRD2_k127_3453118_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 560.0
SRD2_k127_3453118_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 532.0
SRD2_k127_3453118_10 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009281 370.0
SRD2_k127_3453118_11 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 354.0
SRD2_k127_3453118_12 Phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 335.0
SRD2_k127_3453118_13 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001006 278.0
SRD2_k127_3453118_14 lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000845 278.0
SRD2_k127_3453118_15 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000002283 265.0
SRD2_k127_3453118_16 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000002778 255.0
SRD2_k127_3453118_17 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000001087 250.0
SRD2_k127_3453118_18 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000001225 244.0
SRD2_k127_3453118_19 His Kinase A (phosphoacceptor) domain K07641,K10819 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000003672 232.0
SRD2_k127_3453118_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 479.0
SRD2_k127_3453118_20 Cell shape-determining protein K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963 - 0.0000000000000000000000000000000000000000000000000000000848 210.0
SRD2_k127_3453118_21 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000003403 149.0
SRD2_k127_3453118_22 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000000000000005407 124.0
SRD2_k127_3453118_23 Universal stress protein K06149 - - 0.0000000000000000000000001401 111.0
SRD2_k127_3453118_24 PFAM ApaG domain protein K06195 - - 0.000000000000000000001225 95.0
SRD2_k127_3453118_3 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 471.0
SRD2_k127_3453118_4 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 452.0
SRD2_k127_3453118_5 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 413.0
SRD2_k127_3453118_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 405.0
SRD2_k127_3453118_7 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 393.0
SRD2_k127_3453118_8 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 389.0
SRD2_k127_3453118_9 Binding-protein-dependent transport system inner membrane component K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 358.0
SRD2_k127_3461718_0 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K15022 - 1.17.1.10 7.94e-286 900.0
SRD2_k127_3461718_1 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 4.76e-250 796.0
SRD2_k127_3461718_2 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 9.355e-203 646.0
SRD2_k127_3461718_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 490.0
SRD2_k127_3461718_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 347.0
SRD2_k127_3461718_5 Na -driven multidrug efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 312.0
SRD2_k127_3461718_6 - - - - 0.0000000000000000000000000000000000000000000002246 186.0
SRD2_k127_3461718_7 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000003247 175.0
SRD2_k127_3461718_8 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000001353 154.0
SRD2_k127_3461718_9 ubiquinone biosynthetic process from chorismate K03690 GO:0006082,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0019752,GO:0032150,GO:0042180,GO:0042181,GO:0043436,GO:0043648,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046417,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000001811 79.0
SRD2_k127_3469119_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1245.0
SRD2_k127_3469119_1 His Kinase A (phosphoacceptor) domain - - - 1.52e-217 734.0
SRD2_k127_3469119_2 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 523.0
SRD2_k127_3469119_3 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 347.0
SRD2_k127_3469119_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000008859 262.0
SRD2_k127_3469119_5 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002374 262.0
SRD2_k127_3469119_6 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000002911 186.0
SRD2_k127_3469119_7 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.00000000000000000000000000000000000000000000008941 175.0
SRD2_k127_3471840_0 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 2.869e-212 672.0
SRD2_k127_3471840_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 637.0
SRD2_k127_3471840_2 pfam abc K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 293.0
SRD2_k127_3471840_3 Response regulator of the LytR AlgR family K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000584 290.0
SRD2_k127_3471840_4 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000001274 229.0
SRD2_k127_3471840_5 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000001288 183.0
SRD2_k127_3487263_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1843.0
SRD2_k127_3487263_1 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 591.0
SRD2_k127_3487263_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008516 267.0
SRD2_k127_3487263_3 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000002292 229.0
SRD2_k127_3487263_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001476 216.0
SRD2_k127_3487263_5 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000002388 177.0
SRD2_k127_3487263_6 Methyl-transferase - - - 0.00000000000000000000000000000000000000003597 162.0
SRD2_k127_3487263_7 7TM diverse intracellular signalling - - - 0.000000000000000000000000000000000001078 158.0
SRD2_k127_3487263_8 - - - - 0.00000000000000000000000001185 116.0
SRD2_k127_3489955_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1369.0
SRD2_k127_3489955_1 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1094.0
SRD2_k127_3489955_10 Hydantoinase/oxoprolinase N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 516.0
SRD2_k127_3489955_11 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 478.0
SRD2_k127_3489955_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 477.0
SRD2_k127_3489955_13 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 475.0
SRD2_k127_3489955_14 C-terminus of AA_permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 466.0
SRD2_k127_3489955_15 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 477.0
SRD2_k127_3489955_16 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 416.0
SRD2_k127_3489955_17 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K12253 - 4.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 407.0
SRD2_k127_3489955_18 Secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 366.0
SRD2_k127_3489955_19 COG0436 Aspartate tyrosine aromatic aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 366.0
SRD2_k127_3489955_2 receptor K02014 - - 2.287e-253 821.0
SRD2_k127_3489955_20 Queuosine biosynthesis protein QueC K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 332.0
SRD2_k127_3489955_21 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 312.0
SRD2_k127_3489955_22 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 297.0
SRD2_k127_3489955_23 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 304.0
SRD2_k127_3489955_24 Acetamidase formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009878 278.0
SRD2_k127_3489955_25 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000167 253.0
SRD2_k127_3489955_26 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000002929 225.0
SRD2_k127_3489955_27 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000001472 209.0
SRD2_k127_3489955_28 - - - - 0.0000000000000000000000000000000000000000000000000000005724 207.0
SRD2_k127_3489955_29 - - - - 0.0000000000000000000000000000000000000000000000000000008787 203.0
SRD2_k127_3489955_3 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 2.362e-237 743.0
SRD2_k127_3489955_30 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000002245 189.0
SRD2_k127_3489955_31 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000009484 182.0
SRD2_k127_3489955_32 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000004296 165.0
SRD2_k127_3489955_33 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000003725 162.0
SRD2_k127_3489955_34 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000009207 156.0
SRD2_k127_3489955_35 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000002634 151.0
SRD2_k127_3489955_36 Biopolymer transport protein K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000004008 144.0
SRD2_k127_3489955_37 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000007705 84.0
SRD2_k127_3489955_38 TonB C terminal K03646 - - 0.000000000000007284 84.0
SRD2_k127_3489955_39 transcriptional regulator - - - 0.0000000000137 76.0
SRD2_k127_3489955_4 Pyridoxal-phosphate dependent enzyme K01505 - 3.5.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 599.0
SRD2_k127_3489955_40 - - - - 0.000000003427 67.0
SRD2_k127_3489955_41 - - - - 0.0001191 50.0
SRD2_k127_3489955_5 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 615.0
SRD2_k127_3489955_6 E3 component of 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 575.0
SRD2_k127_3489955_7 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 558.0
SRD2_k127_3489955_8 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine K17735 - 1.1.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 523.0
SRD2_k127_3489955_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 507.0
SRD2_k127_3510148_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.721e-226 710.0
SRD2_k127_3510148_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 557.0
SRD2_k127_3510148_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 297.0
SRD2_k127_3510148_11 Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002823 293.0
SRD2_k127_3510148_12 FimV C-terminal K08086 - - 0.0000000000000000000000000000000000000000000000000000000000004492 241.0
SRD2_k127_3510148_13 SCO1/SenC K07152 - - 0.00000000000000000000000000000000002768 142.0
SRD2_k127_3510148_14 membrane protein, required for colicin V production K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.000000000000000000002649 99.0
SRD2_k127_3510148_15 Sporulation related domain K03749 - - 0.000003725 59.0
SRD2_k127_3510148_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 535.0
SRD2_k127_3510148_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 428.0
SRD2_k127_3510148_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 353.0
SRD2_k127_3510148_5 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 320.0
SRD2_k127_3510148_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 314.0
SRD2_k127_3510148_7 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 306.0
SRD2_k127_3510148_8 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 304.0
SRD2_k127_3510148_9 PFAM EAL domain K21025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 317.0
SRD2_k127_352335_0 receptor - - - 6.382e-225 734.0
SRD2_k127_352335_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 555.0
SRD2_k127_352335_10 PKHD-type hydroxylase K07336 - - 0.0000000000000000000000000000000000000000000000000000000000001029 223.0
SRD2_k127_352335_11 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000008578 177.0
SRD2_k127_352335_12 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000002225 139.0
SRD2_k127_352335_13 LppC putative lipoprotein - - - 0.0000000000000000000003512 100.0
SRD2_k127_352335_14 Belongs to the UPF0102 family K07460 - - 0.000000000000000000003748 102.0
SRD2_k127_352335_15 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.000000000000000002937 98.0
SRD2_k127_352335_2 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 441.0
SRD2_k127_352335_3 beta-hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 337.0
SRD2_k127_352335_4 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 316.0
SRD2_k127_352335_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003592 276.0
SRD2_k127_352335_6 Stringent starvation protein A K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001997 260.0
SRD2_k127_352335_7 (Lipo)protein K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000003581 245.0
SRD2_k127_352335_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
SRD2_k127_352335_9 Cytochrome C1 family K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000002216 229.0
SRD2_k127_3597718_0 receptor - - - 7.17e-204 677.0
SRD2_k127_3597718_1 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 559.0
SRD2_k127_3597718_10 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.0000000000000000000000000000000000000000000000000000000004343 208.0
SRD2_k127_3597718_11 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000005642 195.0
SRD2_k127_3597718_12 - - - - 0.000000000000000000000000000000000000000000006042 173.0
SRD2_k127_3597718_13 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000003339 172.0
SRD2_k127_3597718_14 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000002472 159.0
SRD2_k127_3597718_15 IclR helix-turn-helix domain - - - 0.0000000000000000000000000000000000000348 161.0
SRD2_k127_3597718_16 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.00000000000000000000000000000000000004249 146.0
SRD2_k127_3597718_17 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000006021 146.0
SRD2_k127_3597718_18 Phospholipid methyltransferase - - - 0.000000000000000000000000000000005893 138.0
SRD2_k127_3597718_19 Domain of unknown function (DUF4440) - - - 0.0000000000000000000002861 106.0
SRD2_k127_3597718_2 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 484.0
SRD2_k127_3597718_20 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000004549 95.0
SRD2_k127_3597718_21 - - - - 0.000000000000000000196 100.0
SRD2_k127_3597718_22 gag-polyprotein putative aspartyl protease - - - 0.00000000000000004722 88.0
SRD2_k127_3597718_23 Predicted membrane protein (DUF2231) - - - 0.00000000000006029 77.0
SRD2_k127_3597718_24 - - - - 0.00000000007618 68.0
SRD2_k127_3597718_25 NnrU protein - - - 0.0000000006215 63.0
SRD2_k127_3597718_26 LytTr DNA-binding domain - - - 0.000000001824 66.0
SRD2_k127_3597718_27 Polysaccharide lyase - - - 0.00000005813 64.0
SRD2_k127_3597718_3 Amino acid permease K11735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 438.0
SRD2_k127_3597718_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 323.0
SRD2_k127_3597718_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002062 231.0
SRD2_k127_3597718_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004777 235.0
SRD2_k127_3597718_7 Domain of unknown function (DUF4142) K08995 - - 0.000000000000000000000000000000000000000000000000000000000000004591 221.0
SRD2_k127_3597718_8 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000003179 214.0
SRD2_k127_3597718_9 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000001001 226.0
SRD2_k127_3631904_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 442.0
SRD2_k127_3631904_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 332.0
SRD2_k127_3631904_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 312.0
SRD2_k127_3631904_3 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001694 273.0
SRD2_k127_3631904_4 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.000000000000000000000000000000000000000006214 159.0
SRD2_k127_3631904_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000001169 125.0
SRD2_k127_372053_0 Tricorn protease C1 domain K08676 - - 0.0 1324.0
SRD2_k127_372053_1 COG0457 FOG TPR repeat - - - 2.567e-261 829.0
SRD2_k127_372053_10 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000446 266.0
SRD2_k127_372053_11 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000003567 232.0
SRD2_k127_372053_12 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000000000000000002672 221.0
SRD2_k127_372053_13 PFAM Phosphatidic acid phosphatase type 2 haloperoxidase - - - 0.00000000000000000000000000000000000000000000000000001283 206.0
SRD2_k127_372053_14 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000003532 148.0
SRD2_k127_372053_15 Transfers electrons from cytochrome c551 to cytochrome oxidase - - - 0.00000000000000000000000000000000000001571 149.0
SRD2_k127_372053_16 Protein of unknown function (DUF2937) - - - 0.0000000000000000000000000000002801 134.0
SRD2_k127_372053_17 (twin-arginine translocation) pathway signal - - - 0.00000000000209 78.0
SRD2_k127_372053_2 GMC oxidoreductase - - - 3.769e-235 740.0
SRD2_k127_372053_3 Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system K17215 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 601.0
SRD2_k127_372053_4 Belongs to the binding-protein-dependent transport system permease family K10440,K17214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 473.0
SRD2_k127_372053_5 COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family K18459 - 3.5.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 411.0
SRD2_k127_372053_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 371.0
SRD2_k127_372053_7 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K17205,K17213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 368.0
SRD2_k127_372053_8 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 332.0
SRD2_k127_372053_9 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002769 263.0
SRD2_k127_3733052_0 COG1233 Phytoene dehydrogenase and related - - - 8.495e-244 767.0
SRD2_k127_3733052_1 Aldehyde dehydrogenase family K00130,K00137 - 1.2.1.19,1.2.1.8 1.064e-214 676.0
SRD2_k127_3733052_10 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 364.0
SRD2_k127_3733052_11 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 341.0
SRD2_k127_3733052_12 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 312.0
SRD2_k127_3733052_13 COG1177 ABC-type spermidine putrescine transport system, permease component II K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 308.0
SRD2_k127_3733052_14 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 312.0
SRD2_k127_3733052_15 BetI-type transcriptional repressor, C-terminal K02167 - - 0.000000000000000000000000000001692 132.0
SRD2_k127_3733052_16 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000005966 124.0
SRD2_k127_3733052_17 transcriptional regulator - - - 0.00000000000003057 80.0
SRD2_k127_3733052_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 6.707e-200 632.0
SRD2_k127_3733052_3 Short-chain specific acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 582.0
SRD2_k127_3733052_4 COG1042 Acyl-CoA synthetase (NDP forming) K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 516.0
SRD2_k127_3733052_5 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 493.0
SRD2_k127_3733052_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 444.0
SRD2_k127_3733052_7 Belongs to the GcvT family K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 441.0
SRD2_k127_3733052_8 Putrescine transport system permease K11075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 362.0
SRD2_k127_3733052_9 Bacterial extracellular solute-binding protein K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 362.0
SRD2_k127_3819032_0 histidine kinase HAMP region domain protein K07716 - 2.7.13.3 0.0 1467.0
SRD2_k127_3819032_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 552.0
SRD2_k127_3819032_2 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000003282 185.0
SRD2_k127_3819032_3 addiction module antidote protein - - - 0.00000000000000000000000313 107.0
SRD2_k127_3819032_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.0000000000003281 78.0
SRD2_k127_3996495_0 Enoyl-CoA hydratase/isomerase - - - 1.567e-215 691.0
SRD2_k127_3996495_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 544.0
SRD2_k127_3996495_10 MTH538 TIR-like domain (DUF1863) - - - 0.000000000000000001512 97.0
SRD2_k127_3996495_2 component I K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 449.0
SRD2_k127_3996495_3 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 329.0
SRD2_k127_3996495_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002698 290.0
SRD2_k127_3996495_5 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001845 261.0
SRD2_k127_3996495_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000005583 223.0
SRD2_k127_3996495_7 4-amino-4-deoxychorismate lyase K02619 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000002218 226.0
SRD2_k127_3996495_8 Pilus assembly protein PilZ K02676 - - 0.00000000000000000000000000000000000000000000000001171 182.0
SRD2_k127_3996495_9 DNA polymerase III, delta' K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000001835 184.0
SRD2_k127_4006219_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 8.288e-249 782.0
SRD2_k127_4006219_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 551.0
SRD2_k127_4006219_10 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000005316 176.0
SRD2_k127_4006219_2 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 512.0
SRD2_k127_4006219_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 411.0
SRD2_k127_4006219_4 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 346.0
SRD2_k127_4006219_5 PAC sensor-containing diguanylate cyclase phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 366.0
SRD2_k127_4006219_6 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 337.0
SRD2_k127_4006219_7 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 329.0
SRD2_k127_4006219_8 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000004337 240.0
SRD2_k127_4006219_9 Transfers electrons from cytochrome c551 to cytochrome oxidase - - - 0.00000000000000000000000000000000000000000004059 165.0
SRD2_k127_4039122_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.67e-217 687.0
SRD2_k127_4039122_1 modulator of DNA gyrase K03568 - - 2.581e-210 666.0
SRD2_k127_4039122_10 Type II secretory pathway component ExeA K02450,K12283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000324 282.0
SRD2_k127_4039122_11 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001009 270.0
SRD2_k127_4039122_12 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001355 270.0
SRD2_k127_4039122_13 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000009695 249.0
SRD2_k127_4039122_14 DNA polymerase III subunit delta K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000001518 241.0
SRD2_k127_4039122_15 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000001605 226.0
SRD2_k127_4039122_16 AIR carboxylase K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000009276 233.0
SRD2_k127_4039122_17 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000002885 225.0
SRD2_k127_4039122_18 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000007736 224.0
SRD2_k127_4039122_19 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000001119 220.0
SRD2_k127_4039122_2 COG1530 Ribonucleases G and E K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 597.0
SRD2_k127_4039122_20 - - - - 0.0000000000000000000000000000000000000000000000000000000007344 209.0
SRD2_k127_4039122_21 EVE domain - - - 0.000000000000000000000000000000000000000000000000000001687 204.0
SRD2_k127_4039122_22 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000001645 195.0
SRD2_k127_4039122_23 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.0000000000000000000000000000000000000000000000000001647 196.0
SRD2_k127_4039122_24 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000007626 164.0
SRD2_k127_4039122_25 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000001782 142.0
SRD2_k127_4039122_26 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000002373 123.0
SRD2_k127_4039122_27 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000001115 118.0
SRD2_k127_4039122_28 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000003955 98.0
SRD2_k127_4039122_29 membrane - - - 0.0000000000000000002426 105.0
SRD2_k127_4039122_3 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 517.0
SRD2_k127_4039122_30 Lipopolysaccharide-assembly - - - 0.000000000001515 76.0
SRD2_k127_4039122_4 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 415.0
SRD2_k127_4039122_5 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 380.0
SRD2_k127_4039122_6 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 375.0
SRD2_k127_4039122_7 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 345.0
SRD2_k127_4039122_8 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 332.0
SRD2_k127_4039122_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007797 276.0
SRD2_k127_4054354_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 2.603e-287 900.0
SRD2_k127_4054354_1 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 5.102e-217 682.0
SRD2_k127_4054354_10 phosphoglycolate phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 318.0
SRD2_k127_4054354_11 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 298.0
SRD2_k127_4054354_12 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 301.0
SRD2_k127_4054354_13 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001205 292.0
SRD2_k127_4054354_14 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000001415 196.0
SRD2_k127_4054354_15 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000000000001629 186.0
SRD2_k127_4054354_16 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.000000000000000000000000000000002828 132.0
SRD2_k127_4054354_17 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000002709 127.0
SRD2_k127_4054354_18 Dodecin K09165 - - 0.000000000000000000000005553 106.0
SRD2_k127_4054354_19 Sh3 type 3 domain protein K01361 - 3.4.21.96 0.000000000000000000000007229 113.0
SRD2_k127_4054354_2 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K01555 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 576.0
SRD2_k127_4054354_3 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 535.0
SRD2_k127_4054354_4 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 497.0
SRD2_k127_4054354_5 PFAM Ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 491.0
SRD2_k127_4054354_6 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 481.0
SRD2_k127_4054354_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 439.0
SRD2_k127_4054354_8 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 336.0
SRD2_k127_4054354_9 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 338.0
SRD2_k127_4090627_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1168.0
SRD2_k127_4090627_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 310.0
SRD2_k127_4090627_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000002216 261.0
SRD2_k127_4090627_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000001315 222.0
SRD2_k127_4090627_4 CRS1_YhbY K07574 - - 0.000000000000000000001832 106.0
SRD2_k127_4124216_0 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 498.0
SRD2_k127_4124216_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 456.0
SRD2_k127_4124216_2 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 445.0
SRD2_k127_4124216_3 Dehydrogenase K15054 - 1.1.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 418.0
SRD2_k127_4124216_4 Sigma factor regulator FecR K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 402.0
SRD2_k127_4124216_5 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 359.0
SRD2_k127_4124216_6 Glutathione-dependent formaldehyde-activating enzyme K03396 - 4.4.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 291.0
SRD2_k127_4124216_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001329 287.0
SRD2_k127_4124216_8 - - - - 0.000000000000000000000000000000000000000000000000001037 205.0
SRD2_k127_4124216_9 Domain of unknown function (DUF4382) - - - 0.0000000000000000000003351 112.0
SRD2_k127_4152268_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 501.0
SRD2_k127_4152268_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 368.0
SRD2_k127_4152268_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005637 277.0
SRD2_k127_4185005_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 3.107e-291 919.0
SRD2_k127_4185005_1 Outer membrane efflux protein K18300,K19593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 443.0
SRD2_k127_4185005_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 411.0
SRD2_k127_4185005_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 385.0
SRD2_k127_4185005_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000004462 201.0
SRD2_k127_4185005_5 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000002674 134.0
SRD2_k127_4197042_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 610.0
SRD2_k127_4197042_1 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 438.0
SRD2_k127_4197042_10 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000001561 238.0
SRD2_k127_4197042_11 Protein tyrosine kinase K11912 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000005873 219.0
SRD2_k127_4197042_12 Domain of unknown function (DUF4399) - - - 0.0000000000000000000000000000000000000000000166 166.0
SRD2_k127_4197042_13 Protein of unknown function (DUF3667) - - - 0.00000000000000000000000000000000000000006475 168.0
SRD2_k127_4197042_14 - - - - 0.000000000000000000000000000002699 122.0
SRD2_k127_4197042_15 Methyltransferase - - - 0.000000000000000368 87.0
SRD2_k127_4197042_16 membrane K02451,K03832 - - 0.00000000001231 74.0
SRD2_k127_4197042_2 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 414.0
SRD2_k127_4197042_3 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA K06445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 373.0
SRD2_k127_4197042_4 PFAM FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 382.0
SRD2_k127_4197042_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 348.0
SRD2_k127_4197042_6 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 351.0
SRD2_k127_4197042_7 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 333.0
SRD2_k127_4197042_8 COG0438 Glycosyltransferase K14335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 333.0
SRD2_k127_4197042_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005095 295.0
SRD2_k127_4220816_0 trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 551.0
SRD2_k127_4220816_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 514.0
SRD2_k127_4220816_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 477.0
SRD2_k127_4220816_3 alcohol dehydrogenase - - - 0.0004362 43.0
SRD2_k127_4221371_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.718e-197 624.0
SRD2_k127_4221371_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 561.0
SRD2_k127_4221371_10 ATPase or kinase K06925 - - 0.00000000000000000000000000000000137 141.0
SRD2_k127_4221371_11 - - - - 0.000000000000000000001821 99.0
SRD2_k127_4221371_12 Zn-dependent protease with chaperone function K06013 - 3.4.24.84 0.00000000000001207 74.0
SRD2_k127_4221371_13 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000007545 59.0
SRD2_k127_4221371_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 476.0
SRD2_k127_4221371_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 396.0
SRD2_k127_4221371_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 333.0
SRD2_k127_4221371_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 311.0
SRD2_k127_4221371_6 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001317 293.0
SRD2_k127_4221371_7 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004983 294.0
SRD2_k127_4221371_8 HflC and HflK could regulate a protease K04087 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000001019 240.0
SRD2_k127_4221371_9 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000002341 143.0
SRD2_k127_4223236_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 516.0
SRD2_k127_4223236_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001278 283.0
SRD2_k127_4223236_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001073 264.0
SRD2_k127_4223236_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004848 253.0
SRD2_k127_4223236_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000007706 216.0
SRD2_k127_4223236_5 PFAM Amino acid-binding ACT K03567 - - 0.000000000000000000000000000000000000000000000000000002049 195.0
SRD2_k127_4223236_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000837 154.0
SRD2_k127_4223236_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000007993 136.0
SRD2_k127_4250398_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.144e-310 985.0
SRD2_k127_4250398_1 PFAM amino acid permease-associated region K03293,K11735 - - 9.573e-198 632.0
SRD2_k127_4250398_10 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000002356 234.0
SRD2_k127_4250398_11 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
SRD2_k127_4250398_12 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000001545 231.0
SRD2_k127_4250398_13 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase - - - 0.0000000000000000000000000000000000000000000000000000001667 201.0
SRD2_k127_4250398_14 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000003242 192.0
SRD2_k127_4250398_15 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000001931 146.0
SRD2_k127_4250398_16 Prokaryotic cytochrome b561 K12262 - - 0.00000000000000000000000000000005161 132.0
SRD2_k127_4250398_17 glycosyl transferase, family 39 - - - 0.0000000000000000000000000006011 130.0
SRD2_k127_4250398_18 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000159 117.0
SRD2_k127_4250398_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000001783 108.0
SRD2_k127_4250398_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 561.0
SRD2_k127_4250398_20 - - - - 0.000000000000001889 79.0
SRD2_k127_4250398_22 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000003625 52.0
SRD2_k127_4250398_3 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 507.0
SRD2_k127_4250398_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 463.0
SRD2_k127_4250398_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 433.0
SRD2_k127_4250398_6 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 347.0
SRD2_k127_4250398_7 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 338.0
SRD2_k127_4250398_8 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 332.0
SRD2_k127_4250398_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005173 276.0
SRD2_k127_425217_0 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 544.0
SRD2_k127_425217_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 510.0
SRD2_k127_425217_10 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000001259 188.0
SRD2_k127_425217_11 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000005416 178.0
SRD2_k127_425217_12 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000001427 171.0
SRD2_k127_425217_13 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000002691 163.0
SRD2_k127_425217_14 NACHT domain - - - 0.00000000000000000001456 107.0
SRD2_k127_425217_15 Sel1-like repeats. K07126 - - 0.000007653 59.0
SRD2_k127_425217_2 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 480.0
SRD2_k127_425217_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 409.0
SRD2_k127_425217_4 TIGRFAM cytochrome c-type biogenesis protein CcmF K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 361.0
SRD2_k127_425217_5 PFAM trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 360.0
SRD2_k127_425217_6 DNA mediated transformation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 337.0
SRD2_k127_425217_7 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 318.0
SRD2_k127_425217_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000001784 211.0
SRD2_k127_425217_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000001041 215.0
SRD2_k127_4298404_0 DNA segregation ATPase FtsK SpoIIIE K03466 - - 1.93e-269 849.0
SRD2_k127_4298404_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.243e-227 731.0
SRD2_k127_4298404_10 ParB-like nuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001562 257.0
SRD2_k127_4298404_11 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000005988 229.0
SRD2_k127_4298404_12 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000008147 207.0
SRD2_k127_4298404_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000562 150.0
SRD2_k127_4298404_14 PFAM cytochrome c, class I - - - 0.000000000000000000000000000003234 127.0
SRD2_k127_4298404_15 Cytochrome c - - - 0.0000000000000000101 94.0
SRD2_k127_4298404_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 559.0
SRD2_k127_4298404_3 AAA ATPase, central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 570.0
SRD2_k127_4298404_4 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 528.0
SRD2_k127_4298404_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 472.0
SRD2_k127_4298404_6 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 380.0
SRD2_k127_4298404_7 PFAM methylamine dehydrogenase heavy subunit K13372,K15229 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.4.9.1,1.4.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 374.0
SRD2_k127_4298404_8 Pyrimidine nucleoside phosphorylase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001558 258.0
SRD2_k127_4298404_9 PFAM Methylamine dehydrogenase light chain K13371,K15228 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.4.9.1,1.4.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005167 252.0
SRD2_k127_4313061_0 Glycine cleavage T-protein C-terminal barrel domain K00302,K22086 - 1.5.3.1,1.5.99.5 1.262e-308 976.0
SRD2_k127_4313061_1 FAD dependent oxidoreductase central domain - - - 9.977e-301 945.0
SRD2_k127_4313061_10 Binding-protein-dependent transport system inner membrane component K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 300.0
SRD2_k127_4313061_11 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000007823 228.0
SRD2_k127_4313061_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000006191 215.0
SRD2_k127_4313061_13 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000001426 188.0
SRD2_k127_4313061_14 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000001976 183.0
SRD2_k127_4313061_15 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000004209 150.0
SRD2_k127_4313061_16 cellulase activity - - - 0.0000000000000000000000000000000001716 147.0
SRD2_k127_4313061_17 Sarcosine oxidase, delta subunit K00304,K22085 - 1.5.3.1,1.5.99.5 0.0000000000000000000000001802 108.0
SRD2_k127_4313061_18 Histidine kinase - - - 0.000000000000000000000002354 121.0
SRD2_k127_4313061_19 MASE1 - - - 0.0000002208 65.0
SRD2_k127_4313061_2 Major facilitator Superfamily - - - 4.145e-250 782.0
SRD2_k127_4313061_20 Diguanylate cyclase - - - 0.00000115 63.0
SRD2_k127_4313061_21 PAS S-box diguanylate cyclase domain-containing protein - - - 0.00001347 57.0
SRD2_k127_4313061_23 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.0000161 54.0
SRD2_k127_4313061_3 FAD dependent oxidoreductase K00303,K22084 - 1.5.3.1,1.5.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 572.0
SRD2_k127_4313061_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 411.0
SRD2_k127_4313061_5 PFAM ABC transporter K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 394.0
SRD2_k127_4313061_6 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 364.0
SRD2_k127_4313061_7 Permease component K05846 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 367.0
SRD2_k127_4313061_8 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0033554,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0104004 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 349.0
SRD2_k127_4313061_9 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 321.0
SRD2_k127_4352384_0 Glucodextranase, domain N K01178 - 3.2.1.3 1.586e-314 990.0
SRD2_k127_4352384_1 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 8.196e-284 880.0
SRD2_k127_4352384_10 Major facilitator superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 535.0
SRD2_k127_4352384_11 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 517.0
SRD2_k127_4352384_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 412.0
SRD2_k127_4352384_13 ubiquitin protein ligase binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 395.0
SRD2_k127_4352384_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 398.0
SRD2_k127_4352384_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 390.0
SRD2_k127_4352384_16 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 347.0
SRD2_k127_4352384_17 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 352.0
SRD2_k127_4352384_18 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 344.0
SRD2_k127_4352384_19 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 329.0
SRD2_k127_4352384_2 peptidase M13 K07386 - - 3.642e-217 695.0
SRD2_k127_4352384_20 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 324.0
SRD2_k127_4352384_21 chondroitin AC lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 304.0
SRD2_k127_4352384_22 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000004032 268.0
SRD2_k127_4352384_23 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
SRD2_k127_4352384_24 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 256.0
SRD2_k127_4352384_25 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000003403 230.0
SRD2_k127_4352384_26 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000005088 214.0
SRD2_k127_4352384_27 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000001251 227.0
SRD2_k127_4352384_28 - - - - 0.00000000000000000000000000000000000000000000000000000007268 210.0
SRD2_k127_4352384_29 - - - - 0.0000000000000000000000000000000000000000000000000000001646 203.0
SRD2_k127_4352384_3 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 8.109e-216 700.0
SRD2_k127_4352384_30 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000001974 198.0
SRD2_k127_4352384_31 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000006239 201.0
SRD2_k127_4352384_32 COG3103 SH3 domain protein - - - 0.000000000000000000000000000000000000000000000000000005167 200.0
SRD2_k127_4352384_33 - - - - 0.00000000000000000000000000000000000000000000000000005735 197.0
SRD2_k127_4352384_34 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000006204 191.0
SRD2_k127_4352384_35 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000000000001112 184.0
SRD2_k127_4352384_36 AntiSigma factor - - - 0.000000000000000000000000000000000000000000001784 173.0
SRD2_k127_4352384_37 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000001017 166.0
SRD2_k127_4352384_38 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000003352 168.0
SRD2_k127_4352384_39 Nitroreductase - GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000004916 170.0
SRD2_k127_4352384_4 Tetratricopeptide repeat - - - 4.003e-212 691.0
SRD2_k127_4352384_40 PFAM Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000001895 159.0
SRD2_k127_4352384_41 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000534 160.0
SRD2_k127_4352384_42 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000002187 155.0
SRD2_k127_4352384_43 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000001752 149.0
SRD2_k127_4352384_44 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000008258 126.0
SRD2_k127_4352384_45 - - - - 0.0000000000000000000000000005793 117.0
SRD2_k127_4352384_46 Thioredoxin-like - - - 0.000000000000000000000000001332 125.0
SRD2_k127_4352384_47 Domain of unknown function (DUF4184) - - - 0.0000000000000000000005144 106.0
SRD2_k127_4352384_48 Domain of unknown function (DUF4266) - - - 0.000000000000000000001532 98.0
SRD2_k127_4352384_49 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000611 108.0
SRD2_k127_4352384_5 Concanavalin A-like lectin/glucanases superfamily - - - 8.654e-200 652.0
SRD2_k127_4352384_50 COG0457 FOG TPR repeat - - - 0.0000000000000000000392 102.0
SRD2_k127_4352384_51 - - - - 0.0000000000000001953 88.0
SRD2_k127_4352384_52 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000007668 78.0
SRD2_k127_4352384_6 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 610.0
SRD2_k127_4352384_7 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 591.0
SRD2_k127_4352384_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 543.0
SRD2_k127_4352384_9 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 550.0
SRD2_k127_4356716_0 ABC transporter - - - 4.185e-261 812.0
SRD2_k127_4356716_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.458e-203 642.0
SRD2_k127_4356716_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004556 282.0
SRD2_k127_4356716_11 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000006978 218.0
SRD2_k127_4356716_12 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000517 210.0
SRD2_k127_4356716_13 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000006149 176.0
SRD2_k127_4356716_14 Thioredoxin - - - 0.00000000000000000000000000000000006478 139.0
SRD2_k127_4356716_15 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000003597 130.0
SRD2_k127_4356716_16 PFAM PsiF repeat protein - - - 0.00007287 49.0
SRD2_k127_4356716_2 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 392.0
SRD2_k127_4356716_3 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 388.0
SRD2_k127_4356716_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 385.0
SRD2_k127_4356716_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 378.0
SRD2_k127_4356716_6 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 361.0
SRD2_k127_4356716_7 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 358.0
SRD2_k127_4356716_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 312.0
SRD2_k127_4356716_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 295.0
SRD2_k127_4384967_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 9.312e-306 943.0
SRD2_k127_4384967_1 PTS system, glucose subfamily, IIA K11189 - - 4.119e-239 768.0
SRD2_k127_4384967_2 PTS system, N-acetylglucosamine-specific K02803,K02804 - 2.7.1.193 1.026e-203 650.0
SRD2_k127_4384967_3 Catalyzes the degradation of histidine to urocanate and ammmonia K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 567.0
SRD2_k127_4384967_4 TIGRFAM Imidazolonepropionase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 427.0
SRD2_k127_4384967_5 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000003321 198.0
SRD2_k127_4384967_6 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000009205 144.0
SRD2_k127_4384967_7 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000000000000007732 105.0
SRD2_k127_4384967_8 Participates in both transcription termination and antitermination K02600 - - 0.000000000000009821 74.0
SRD2_k127_44820_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.073e-250 797.0
SRD2_k127_44820_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.244e-231 737.0
SRD2_k127_44820_10 PFAM YicC-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006738 277.0
SRD2_k127_44820_11 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000267 283.0
SRD2_k127_44820_12 cytochrome c-type protein K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002446 261.0
SRD2_k127_44820_13 Protein of unknown function (DUF3307) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003067 251.0
SRD2_k127_44820_14 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000001756 232.0
SRD2_k127_44820_15 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000001979 222.0
SRD2_k127_44820_16 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000001885 213.0
SRD2_k127_44820_17 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000001077 212.0
SRD2_k127_44820_18 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000001017 192.0
SRD2_k127_44820_19 - - - - 0.0000000000000000000000000000000000000000000000001181 184.0
SRD2_k127_44820_2 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 1.332e-216 694.0
SRD2_k127_44820_20 Endoribonuclease K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000002523 188.0
SRD2_k127_44820_21 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000005063 142.0
SRD2_k127_44820_22 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000004551 120.0
SRD2_k127_44820_23 PFAM cytochrome c class I K08738 - - 0.00000000000000000000000000002451 123.0
SRD2_k127_44820_24 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000001276 100.0
SRD2_k127_44820_25 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000001777 100.0
SRD2_k127_44820_26 - - - - 0.00000001057 66.0
SRD2_k127_44820_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 611.0
SRD2_k127_44820_4 Pfam:HipA_N K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 584.0
SRD2_k127_44820_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 426.0
SRD2_k127_44820_6 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 375.0
SRD2_k127_44820_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 350.0
SRD2_k127_44820_8 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 316.0
SRD2_k127_44820_9 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001026 284.0
SRD2_k127_4529878_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 417.0
SRD2_k127_4529878_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 344.0
SRD2_k127_4529878_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 334.0
SRD2_k127_4529878_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009539 278.0
SRD2_k127_4529878_4 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000004224 270.0
SRD2_k127_4529878_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000002454 221.0
SRD2_k127_4529878_6 PFAM methyltransferase - - - 0.00000000000000000000000000000000000001019 154.0
SRD2_k127_4593788_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1403.0
SRD2_k127_4593788_1 Ferrous iron transport protein B K04759 - - 2.591e-246 781.0
SRD2_k127_4593788_10 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000001752 59.0
SRD2_k127_4593788_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.047e-204 646.0
SRD2_k127_4593788_3 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 421.0
SRD2_k127_4593788_4 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 407.0
SRD2_k127_4593788_5 Transporter K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 315.0
SRD2_k127_4593788_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000001746 197.0
SRD2_k127_4593788_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000001136 138.0
SRD2_k127_4593788_8 -acetyltransferase - - - 0.0000000000000000000000008071 110.0
SRD2_k127_4593788_9 FeoA K04758 - - 0.00000000001743 69.0
SRD2_k127_4627675_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1632.0
SRD2_k127_4627675_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00122 - 1.17.1.9 2.472e-317 979.0
SRD2_k127_4627675_10 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 309.0
SRD2_k127_4627675_11 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001448 288.0
SRD2_k127_4627675_12 serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004121 286.0
SRD2_k127_4627675_13 Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000006753 237.0
SRD2_k127_4627675_14 Eukaryotic integral membrane protein (DUF1751) - - - 0.0000000000000000000000000000000000000000000000000000000000001269 218.0
SRD2_k127_4627675_15 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000008367 183.0
SRD2_k127_4627675_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000001653 174.0
SRD2_k127_4627675_17 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000001301 119.0
SRD2_k127_4627675_18 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.00000000000000000000000007941 115.0
SRD2_k127_4627675_19 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000003532 91.0
SRD2_k127_4627675_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 603.0
SRD2_k127_4627675_20 - - - - 0.0000000000000098 83.0
SRD2_k127_4627675_3 Beta-ketoacyl synthase, N-terminal domain K00626,K00632,K02615,K07823 GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016740,GO:0016746,GO:0016747,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0033554,GO:0033812,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 2.3.1.16,2.3.1.174,2.3.1.223,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 564.0
SRD2_k127_4627675_4 Molybdate transporter of MFS superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 453.0
SRD2_k127_4627675_5 PFAM pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 432.0
SRD2_k127_4627675_6 PBP superfamily domain K07219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 400.0
SRD2_k127_4627675_7 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 354.0
SRD2_k127_4627675_8 dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 347.0
SRD2_k127_4627675_9 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 368.0
SRD2_k127_4692149_0 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 481.0
SRD2_k127_4692149_1 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 340.0
SRD2_k127_4692149_2 taurine catabolism dioxygenase K00471 - 1.14.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005568 283.0
SRD2_k127_4692149_3 Phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003104 282.0
SRD2_k127_4692149_4 PFAM FAD linked oxidase K00104,K11472 - 1.1.3.15 0.000000000000009395 75.0
SRD2_k127_4728176_0 chemotaxis protein K03407 - 2.7.13.3 3.648e-194 629.0
SRD2_k127_4728176_1 ATPase FliI YscN family K02412 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 389.0
SRD2_k127_4728176_2 methyl-accepting chemotaxis protein K03406,K03776,K05874 - - 0.0000000000000000000000000000000000000000000000000000006127 209.0
SRD2_k127_4728176_3 Chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble K03413 - - 0.00000000000000000000000000000000000000000000000000002115 190.0
SRD2_k127_4728176_4 chemotaxis signal transduction protein K03408 - - 0.000000000000000000000000000000000000000000006332 169.0
SRD2_k127_4728176_5 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.00000000000000000000000000000000003398 151.0
SRD2_k127_4728176_6 flagellar assembly protein FliH K02411 - - 0.0000000000000000000000000000000717 133.0
SRD2_k127_4728176_7 antisigma factor binding K03409,K05946 - 2.4.1.187 0.0000000003086 66.0
SRD2_k127_4731084_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 7.664e-268 839.0
SRD2_k127_4731084_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.3e-218 683.0
SRD2_k127_4731084_10 Peptidoglycan-binding domain 1 protein - - - 0.00000000000004303 83.0
SRD2_k127_4731084_2 Sulfate permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 587.0
SRD2_k127_4731084_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 526.0
SRD2_k127_4731084_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 339.0
SRD2_k127_4731084_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005137 274.0
SRD2_k127_4731084_6 Peptidase C13 family - - - 0.0000000000000000000000000000000000000000000000000000000005259 220.0
SRD2_k127_4731084_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000001923 176.0
SRD2_k127_4731084_8 TIR domain - - - 0.00000000000000000000000001592 126.0
SRD2_k127_4752140_0 transport system involved in gliding motility, auxiliary component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 570.0
SRD2_k127_4752140_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 366.0
SRD2_k127_4752140_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000003334 243.0
SRD2_k127_4752140_3 - - - - 0.0000000000000000000000000000000000000000000000000000004395 203.0
SRD2_k127_4752140_4 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000001493 136.0
SRD2_k127_4752140_5 Domain of unknown function (DUF4340) - - - 0.00000000000000000002617 106.0
SRD2_k127_4752140_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0001315 44.0
SRD2_k127_4793231_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.827e-196 618.0
SRD2_k127_4793231_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 542.0
SRD2_k127_4793231_10 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000001858 91.0
SRD2_k127_4793231_2 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 471.0
SRD2_k127_4793231_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 354.0
SRD2_k127_4793231_4 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 293.0
SRD2_k127_4793231_5 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000008577 252.0
SRD2_k127_4793231_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000003488 181.0
SRD2_k127_4793231_7 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000006844 178.0
SRD2_k127_4793231_8 Forkhead associated domain - - - 0.0000000000000000000000000000000000002957 146.0
SRD2_k127_4793231_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000001851 133.0
SRD2_k127_488979_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 496.0
SRD2_k127_488979_1 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 461.0
SRD2_k127_488979_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 414.0
SRD2_k127_488979_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 417.0
SRD2_k127_488979_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 398.0
SRD2_k127_488979_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 374.0
SRD2_k127_488979_6 phosphate transport system permease K02038 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 372.0
SRD2_k127_488979_7 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 333.0
SRD2_k127_488979_8 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 320.0
SRD2_k127_488979_9 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000000000000002947 171.0
SRD2_k127_4995727_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000007109 268.0
SRD2_k127_4995727_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000002764 239.0
SRD2_k127_4995727_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000003334 243.0
SRD2_k127_4995727_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000001245 219.0
SRD2_k127_4995727_5 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000003165 58.0
SRD2_k127_510398_0 Belongs to the CarA family K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 535.0
SRD2_k127_510398_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 510.0
SRD2_k127_510398_2 Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 492.0
SRD2_k127_510398_3 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002928 252.0
SRD2_k127_510398_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000003187 215.0
SRD2_k127_5128343_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1386.0
SRD2_k127_5128343_1 Glycine cleavage T-protein C-terminal barrel domain K00302 - 1.5.3.1 0.0 1350.0
SRD2_k127_5128343_10 PFAM helix-turn-helix- domain containing protein, AraC type K21826 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 439.0
SRD2_k127_5128343_11 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 376.0
SRD2_k127_5128343_12 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002162 258.0
SRD2_k127_5128343_13 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000009469 235.0
SRD2_k127_5128343_14 Sarcosine oxidase, gamma subunit family - - - 0.000000000000000000000000000000000000008097 153.0
SRD2_k127_5128343_15 Sarcosine oxidase, delta subunit family K00304 - 1.5.3.1 0.00000000000000000000000000000000000001699 146.0
SRD2_k127_5128343_16 PFAM CcdB protein K19163 - - 0.00000000000000000000000003116 110.0
SRD2_k127_5128343_17 Virulence factor - - - 0.000000000000000007135 93.0
SRD2_k127_5128343_18 PFAM Post-segregation antitoxin CcdA K19164 - - 0.000000004025 60.0
SRD2_k127_5128343_19 TonB-dependent Receptor Plug Domain - - - 0.000006093 48.0
SRD2_k127_5128343_2 Domain of unknown function (DUF4445) - - - 2.02e-295 931.0
SRD2_k127_5128343_3 GMC oxidoreductase K00108 - 1.1.99.1 4.586e-271 842.0
SRD2_k127_5128343_4 Amino acid permease - - - 8.824e-268 831.0
SRD2_k127_5128343_5 Sulfotransferase family - - - 3.54e-238 756.0
SRD2_k127_5128343_6 FAD dependent oxidoreductase K00303 - 1.5.3.1 3.244e-229 715.0
SRD2_k127_5128343_7 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 1.477e-212 682.0
SRD2_k127_5128343_8 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 582.0
SRD2_k127_5128343_9 Vitamin B12 dependent methionine synthase activation K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 472.0
SRD2_k127_5209991_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 524.0
SRD2_k127_5209991_1 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 468.0
SRD2_k127_5209991_10 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000001149 145.0
SRD2_k127_5209991_11 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000005268 69.0
SRD2_k127_5209991_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 430.0
SRD2_k127_5209991_3 Belongs to the peptidase S1C family K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 402.0
SRD2_k127_5209991_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 370.0
SRD2_k127_5209991_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 358.0
SRD2_k127_5209991_6 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 302.0
SRD2_k127_5209991_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001946 284.0
SRD2_k127_5209991_8 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001022 268.0
SRD2_k127_5209991_9 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000008316 151.0
SRD2_k127_5258139_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 443.0
SRD2_k127_5258139_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 335.0
SRD2_k127_5258139_2 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 321.0
SRD2_k127_5258139_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000001127 206.0
SRD2_k127_5258139_4 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000001058 95.0
SRD2_k127_5258139_5 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000002371 77.0
SRD2_k127_5258139_6 Alanine-zipper, major outer membrane lipoprotein - - - 0.000005463 53.0
SRD2_k127_5281508_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.711e-212 681.0
SRD2_k127_5281508_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 625.0
SRD2_k127_5281508_10 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000002018 185.0
SRD2_k127_5281508_11 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000004501 111.0
SRD2_k127_5281508_12 Belongs to the skp family K06142 - - 0.0000000000000000001499 96.0
SRD2_k127_5281508_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 443.0
SRD2_k127_5281508_3 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 399.0
SRD2_k127_5281508_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 383.0
SRD2_k127_5281508_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 325.0
SRD2_k127_5281508_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 321.0
SRD2_k127_5281508_7 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0000270,GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002847 278.0
SRD2_k127_5281508_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000001127 217.0
SRD2_k127_5281508_9 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000006261 196.0
SRD2_k127_5374214_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1073.0
SRD2_k127_5374214_1 Sugar (and other) transporter - - - 3.981e-232 743.0
SRD2_k127_5374214_10 quinolinate catabolic process K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 388.0
SRD2_k127_5374214_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 348.0
SRD2_k127_5374214_12 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007163 278.0
SRD2_k127_5374214_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005375 265.0
SRD2_k127_5374214_14 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000647 224.0
SRD2_k127_5374214_15 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000007289 242.0
SRD2_k127_5374214_16 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000005633 221.0
SRD2_k127_5374214_17 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000001473 203.0
SRD2_k127_5374214_18 transcriptional - - - 0.0000000000000000000000000000000000000000000002237 184.0
SRD2_k127_5374214_19 Domain of unknown function (DUF374) - - - 0.000000000000000000000000000000000000000000002537 177.0
SRD2_k127_5374214_2 Diguanylate cyclase - - - 4.86e-204 665.0
SRD2_k127_5374214_20 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000005404 168.0
SRD2_k127_5374214_21 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000001718 154.0
SRD2_k127_5374214_22 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000000000001267 149.0
SRD2_k127_5374214_23 belongs to the Fur family K09826 - - 0.000000000000000000000000000000005929 133.0
SRD2_k127_5374214_24 receptor K16090 - - 0.00000000000000000000004518 115.0
SRD2_k127_5374214_25 protein contain chitin-binding domain type 3 K01183,K21606 - 3.2.1.14,3.2.1.202 0.000000002595 70.0
SRD2_k127_5374214_26 Domain of unknown function (DUF4397) - - - 0.00000004244 66.0
SRD2_k127_5374214_27 Protein of unknown function (DUF1289) - - - 0.0000009536 60.0
SRD2_k127_5374214_28 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000284 51.0
SRD2_k127_5374214_3 outer membrane efflux protein - - - 5.909e-197 638.0
SRD2_k127_5374214_4 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 613.0
SRD2_k127_5374214_5 COG1566 Multidrug resistance efflux pump K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 512.0
SRD2_k127_5374214_6 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 481.0
SRD2_k127_5374214_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 454.0
SRD2_k127_5374214_8 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 451.0
SRD2_k127_5374214_9 PFAM Cytochrome P450 K14338 - 1.14.14.1,1.6.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 440.0
SRD2_k127_5378937_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.362e-264 832.0
SRD2_k127_5378937_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 529.0
SRD2_k127_5378937_2 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 425.0
SRD2_k127_5378937_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 350.0
SRD2_k127_5437709_0 Homospermidine synthase K00808 - 2.5.1.44 4.603e-233 728.0
SRD2_k127_5437709_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.346e-215 691.0
SRD2_k127_5437709_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 309.0
SRD2_k127_5437709_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000001678 218.0
SRD2_k127_5437709_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000008036 205.0
SRD2_k127_5449166_0 Rossmann fold nucleotide-binding protein K06966 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016798,GO:0016799,GO:0044424,GO:0044444,GO:0044464,GO:0047405 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 615.0
SRD2_k127_5449166_1 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 497.0
SRD2_k127_5449166_2 Molecular chaperone. Has ATPase activity K04079 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 482.0
SRD2_k127_5449166_3 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 312.0
SRD2_k127_5449166_4 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009482 252.0
SRD2_k127_5449166_5 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000004074 164.0
SRD2_k127_5449166_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000396 164.0
SRD2_k127_5594940_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2469.0
SRD2_k127_5594940_1 chondroitin AC lyase activity K00694,K01210,K03292 - 2.4.1.12,3.2.1.58 0.0 1080.0
SRD2_k127_5594940_10 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 504.0
SRD2_k127_5594940_11 COG4206 Outer membrane cobalamin receptor protein K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 491.0
SRD2_k127_5594940_12 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 477.0
SRD2_k127_5594940_13 TonB-dependent receptor plug - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 479.0
SRD2_k127_5594940_14 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 454.0
SRD2_k127_5594940_15 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 466.0
SRD2_k127_5594940_16 DNA repair photolyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 421.0
SRD2_k127_5594940_17 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 409.0
SRD2_k127_5594940_18 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 326.0
SRD2_k127_5594940_19 xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 304.0
SRD2_k127_5594940_2 Beta-lactamase - - - 7.267e-243 782.0
SRD2_k127_5594940_20 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005633 276.0
SRD2_k127_5594940_21 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001176 244.0
SRD2_k127_5594940_22 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000001294 247.0
SRD2_k127_5594940_23 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000001192 234.0
SRD2_k127_5594940_24 NADP-dependent oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000002081 232.0
SRD2_k127_5594940_25 Acetolactate synthase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000005029 182.0
SRD2_k127_5594940_26 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000002594 184.0
SRD2_k127_5594940_27 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000002133 170.0
SRD2_k127_5594940_28 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000000000003241 123.0
SRD2_k127_5594940_29 NlpC/P60 family - - - 0.00000000000000000000000002126 120.0
SRD2_k127_5594940_3 Amidohydrolase family - - - 1.126e-240 767.0
SRD2_k127_5594940_30 - - - - 0.00000000000000000000004124 101.0
SRD2_k127_5594940_31 PFAM Forkhead-associated protein - - - 0.000000000005402 77.0
SRD2_k127_5594940_32 Thioesterase domain - - - 0.00000000002863 68.0
SRD2_k127_5594940_33 alpha/beta hydrolase fold - - - 0.0000000001156 75.0
SRD2_k127_5594940_34 Protein of unknown function (DUF3429) - - - 0.00005483 53.0
SRD2_k127_5594940_4 Beta-lactamase - - - 9.494e-222 707.0
SRD2_k127_5594940_5 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 4.777e-210 664.0
SRD2_k127_5594940_6 Amidohydrolase family K06015 - 3.5.1.81 3.798e-203 674.0
SRD2_k127_5594940_7 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 1.934e-196 621.0
SRD2_k127_5594940_8 Cystathionine beta-synthase K01697 - 4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 603.0
SRD2_k127_5594940_9 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 565.0
SRD2_k127_5630391_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 481.0
SRD2_k127_5630391_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 346.0
SRD2_k127_5630391_2 permease K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000001326 240.0
SRD2_k127_5630391_3 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000000000003221 197.0
SRD2_k127_5630391_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000008248 134.0
SRD2_k127_5640432_0 helix-turn-helix- domain containing protein, AraC type K13633 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 438.0
SRD2_k127_5640432_1 Extradiol ring-cleavage dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 393.0
SRD2_k127_5640432_2 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 356.0
SRD2_k127_5640432_3 Protein of unknown function (DUF3443) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 306.0
SRD2_k127_5640432_4 domain protein - - - 0.000000000000000000000000000000000000000000000000005905 186.0
SRD2_k127_5640432_5 - - - - 0.0000003262 52.0
SRD2_k127_5640432_6 Protein of unknown function (DUF2844) - - - 0.00000546 48.0
SRD2_k127_5667993_0 receptor K02014 - - 0.0 1135.0
SRD2_k127_5667993_1 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 579.0
SRD2_k127_5667993_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 540.0
SRD2_k127_5667993_3 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 399.0
SRD2_k127_5667993_4 beta-hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 347.0
SRD2_k127_5667993_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
SRD2_k127_5667993_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000531 63.0
SRD2_k127_5667993_8 - - - - 0.00004962 55.0
SRD2_k127_5804537_0 PFAM Type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 419.0
SRD2_k127_5804537_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 394.0
SRD2_k127_5804537_2 Oxidoreductase FAD-binding domain K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 391.0
SRD2_k127_5804537_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 333.0
SRD2_k127_5804537_4 response regulator receiver K02657 - - 0.0000000000000000000000000000000000000000000000000000000000009537 211.0
SRD2_k127_5804537_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000192 220.0
SRD2_k127_5804537_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000001787 123.0
SRD2_k127_5804537_7 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.0000000000000000000000002455 117.0
SRD2_k127_5804537_8 response regulator receiver K02658 - - 0.00000000000000000000002641 108.0
SRD2_k127_5804537_9 - - - - 0.0000339 55.0
SRD2_k127_5931863_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.936e-241 759.0
SRD2_k127_5931863_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.027e-207 657.0
SRD2_k127_5931863_10 biopolymer transport protein K03559 - - 0.000000000002451 70.0
SRD2_k127_5931863_11 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000006639 59.0
SRD2_k127_5931863_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 612.0
SRD2_k127_5931863_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 472.0
SRD2_k127_5931863_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 445.0
SRD2_k127_5931863_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 437.0
SRD2_k127_5931863_6 cystathionine K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 405.0
SRD2_k127_5931863_7 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbD K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001914 281.0
SRD2_k127_5931863_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000008624 264.0
SRD2_k127_5931863_9 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000004147 173.0
SRD2_k127_5988621_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1607.0
SRD2_k127_5988621_1 cellulose binding - - - 0.0 1257.0
SRD2_k127_5988621_10 outer membrane efflux protein - - - 1.011e-194 620.0
SRD2_k127_5988621_11 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 548.0
SRD2_k127_5988621_12 aminopeptidase activity K05994 - 3.4.11.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 543.0
SRD2_k127_5988621_13 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 555.0
SRD2_k127_5988621_14 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 504.0
SRD2_k127_5988621_15 COGs COG4299 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 473.0
SRD2_k127_5988621_16 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 466.0
SRD2_k127_5988621_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 466.0
SRD2_k127_5988621_18 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 439.0
SRD2_k127_5988621_19 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 419.0
SRD2_k127_5988621_2 Aldehyde oxidase and xanthine dehydrogenase K03520 - 1.2.5.3 0.0 1236.0
SRD2_k127_5988621_20 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 419.0
SRD2_k127_5988621_21 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 408.0
SRD2_k127_5988621_22 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 406.0
SRD2_k127_5988621_23 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 396.0
SRD2_k127_5988621_24 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 387.0
SRD2_k127_5988621_25 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 369.0
SRD2_k127_5988621_26 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 360.0
SRD2_k127_5988621_27 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 346.0
SRD2_k127_5988621_28 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 336.0
SRD2_k127_5988621_29 COGs COG2423 ornithine cyclodeaminase mu-crystallin homolog K01750,K21721 - 1.5.1.51,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 320.0
SRD2_k127_5988621_3 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain K01205 - 3.2.1.50 2.762e-312 974.0
SRD2_k127_5988621_30 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 306.0
SRD2_k127_5988621_31 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 292.0
SRD2_k127_5988621_32 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002139 294.0
SRD2_k127_5988621_33 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000256 283.0
SRD2_k127_5988621_34 activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002398 257.0
SRD2_k127_5988621_35 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008767 265.0
SRD2_k127_5988621_36 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002127 248.0
SRD2_k127_5988621_37 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000003376 243.0
SRD2_k127_5988621_38 AraC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002705 231.0
SRD2_k127_5988621_39 radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000001246 230.0
SRD2_k127_5988621_4 Na+/Pi-cotransporter K03324 - - 8.465e-269 835.0
SRD2_k127_5988621_40 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000000000000000000000002801 225.0
SRD2_k127_5988621_41 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000001161 217.0
SRD2_k127_5988621_42 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000002841 200.0
SRD2_k127_5988621_43 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000000002498 188.0
SRD2_k127_5988621_44 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000001518 159.0
SRD2_k127_5988621_45 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000008281 163.0
SRD2_k127_5988621_46 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000001855 154.0
SRD2_k127_5988621_47 Succinate dehydrogenase Fumarate reductase K00241 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000001497 151.0
SRD2_k127_5988621_48 carbon monoxide dehydrogenase K09386 - - 0.00000000000000000000000000000000000001421 156.0
SRD2_k127_5988621_49 TIR domain - - - 0.00000000000000000000000000002852 132.0
SRD2_k127_5988621_5 Serine carboxypeptidase - - - 1.283e-224 708.0
SRD2_k127_5988621_50 succinate dehydrogenase - - - 0.0000000000000000000000000001674 119.0
SRD2_k127_5988621_51 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000004843 113.0
SRD2_k127_5988621_52 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000003248 81.0
SRD2_k127_5988621_53 - - - - 0.000000000001678 72.0
SRD2_k127_5988621_55 - - - - 0.0000000007846 66.0
SRD2_k127_5988621_6 Peptidase, M20 - - - 2.445e-221 695.0
SRD2_k127_5988621_7 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 8.745e-221 712.0
SRD2_k127_5988621_8 Glycosyl hydrolases family 15 - - - 2.717e-213 679.0
SRD2_k127_5988621_9 COG1228 Imidazolonepropionase and related amidohydrolases - - - 4.016e-204 642.0
SRD2_k127_6068065_0 PFAM peptidase M61 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 507.0
SRD2_k127_6068065_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000001269 214.0
SRD2_k127_6068065_2 Predicted permease YjgP/YjgQ family K11720 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0033036,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000006663 193.0
SRD2_k127_6068065_3 permease K07091 - - 0.00000000000000000000000000000000000000018 157.0
SRD2_k127_6068065_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000001745 68.0
SRD2_k127_6068065_5 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00001984 53.0
SRD2_k127_6088745_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 1.914e-233 735.0
SRD2_k127_6088745_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 7.891e-230 720.0
SRD2_k127_6088745_2 mandelate racemase muconate lactonizing K01684,K01781,K08323 - 4.2.1.6,4.2.1.8,5.1.2.2 2.505e-200 634.0
SRD2_k127_6088745_3 belongs to the aldehyde dehydrogenase family K09472 - 1.2.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 605.0
SRD2_k127_6088745_4 of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 448.0
SRD2_k127_6088745_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001173 286.0
SRD2_k127_6088745_6 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000001073 178.0
SRD2_k127_6118161_0 Belongs to the purine-cytosine permease (2.A.39) family K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 615.0
SRD2_k127_6118161_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 527.0
SRD2_k127_6118161_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000005391 190.0
SRD2_k127_6118161_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000000000000000000008786 168.0
SRD2_k127_6118161_12 SnoaL-like domain - - - 0.00000000000000000000000000006326 122.0
SRD2_k127_6118161_13 - - - - 0.00000000000000000000000001583 119.0
SRD2_k127_6118161_14 BetI-type transcriptional repressor, C-terminal - - - 0.0000000000000000000006443 103.0
SRD2_k127_6118161_15 cytochrome C oxidoreductase subunit B - - - 0.00000000000000006372 91.0
SRD2_k127_6118161_16 Protein of unknown function (DUF2934) - - - 0.000000000157 66.0
SRD2_k127_6118161_17 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.00002967 53.0
SRD2_k127_6118161_2 3-Hydroxyisobutyrate Dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 454.0
SRD2_k127_6118161_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 449.0
SRD2_k127_6118161_4 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 445.0
SRD2_k127_6118161_5 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 397.0
SRD2_k127_6118161_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 331.0
SRD2_k127_6118161_7 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006952 254.0
SRD2_k127_6118161_8 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000004041 213.0
SRD2_k127_6118161_9 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000006184 209.0
SRD2_k127_6224964_0 Mg-protoporphyrin IX monomethyl ester oxidative cyclase K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 614.0
SRD2_k127_6224964_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 601.0
SRD2_k127_6224964_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 499.0
SRD2_k127_6224964_3 Histidine kinase K05962 - 2.7.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007385 295.0
SRD2_k127_6224964_4 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000003209 248.0
SRD2_k127_6224964_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004798 244.0
SRD2_k127_6224964_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001144 188.0
SRD2_k127_6224964_7 PFAM Bacterial protein of - - - 0.000000003049 67.0
SRD2_k127_6224964_8 - - - - 0.0000004408 51.0
SRD2_k127_6224964_9 ATP-independent chaperone mediated protein folding K06006 - - 0.0003878 50.0
SRD2_k127_6271834_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 434.0
SRD2_k127_6271834_1 ABC transporter ATP-binding protein K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 342.0
SRD2_k127_6271834_2 Sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000276 134.0
SRD2_k127_6271834_3 Displays ATPase and GTPase activities K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000004307 98.0
SRD2_k127_6271834_4 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.00000001079 65.0
SRD2_k127_6348100_0 Carbohydrate phosphorylase - - - 9.941e-244 764.0
SRD2_k127_6348100_1 oxidase, subunit K00425 - 1.10.3.14 8.671e-240 752.0
SRD2_k127_6348100_10 KR domain K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 319.0
SRD2_k127_6348100_11 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003733 273.0
SRD2_k127_6348100_12 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000001 242.0
SRD2_k127_6348100_13 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000001106 239.0
SRD2_k127_6348100_14 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000003254 211.0
SRD2_k127_6348100_15 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000001203 189.0
SRD2_k127_6348100_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000001249 169.0
SRD2_k127_6348100_17 CoA-binding domain protein K09181 - - 0.00000000000000000000000000000000000000000002095 169.0
SRD2_k127_6348100_18 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000004661 149.0
SRD2_k127_6348100_19 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000001076 146.0
SRD2_k127_6348100_2 NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 606.0
SRD2_k127_6348100_20 BON domain K04065 - - 0.0000000000000000000000000000000001474 138.0
SRD2_k127_6348100_21 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000003925 118.0
SRD2_k127_6348100_22 Cytochrome c - - - 0.0000000000000000004075 95.0
SRD2_k127_6348100_23 oxidoreductase activity, acting on diphenols and related substances as donors K00424 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019867,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0071944 1.10.3.14 0.00000003855 57.0
SRD2_k127_6348100_3 oxidase, subunit K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 484.0
SRD2_k127_6348100_4 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 462.0
SRD2_k127_6348100_5 Phosphate acetyl/butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 409.0
SRD2_k127_6348100_6 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 344.0
SRD2_k127_6348100_7 ErfK YbiS YcfS YnhG family protein K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 358.0
SRD2_k127_6348100_8 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 340.0
SRD2_k127_6348100_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 348.0
SRD2_k127_6391397_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1504.0
SRD2_k127_6391397_1 Acetolactate synthase K01652 - 2.2.1.6 3.4e-253 793.0
SRD2_k127_6391397_10 COG0729 Outer membrane protein K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 314.0
SRD2_k127_6391397_11 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 295.0
SRD2_k127_6391397_12 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000005999 250.0
SRD2_k127_6391397_13 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000006658 229.0
SRD2_k127_6391397_14 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001298 236.0
SRD2_k127_6391397_15 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000000001352 219.0
SRD2_k127_6391397_16 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000001345 185.0
SRD2_k127_6391397_17 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.0000000000000000000000000000000000000000000000001534 195.0
SRD2_k127_6391397_18 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000002494 176.0
SRD2_k127_6391397_19 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000001738 97.0
SRD2_k127_6391397_2 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 405.0
SRD2_k127_6391397_3 Arginosuccinate synthase K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 404.0
SRD2_k127_6391397_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 398.0
SRD2_k127_6391397_5 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 363.0
SRD2_k127_6391397_6 protein involved in formation of curli polymers - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 344.0
SRD2_k127_6391397_7 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 345.0
SRD2_k127_6391397_8 protein conserved in bacteria K09800 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 371.0
SRD2_k127_6391397_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 321.0
SRD2_k127_6437375_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 0.0 1552.0
SRD2_k127_6437375_1 Uncharacterised conserved protein (DUF2156) K07027,K14205 - 2.3.2.3 3.514e-269 853.0
SRD2_k127_6437375_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 434.0
SRD2_k127_6437375_3 Bacterial virulence protein (VirJ) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 425.0
SRD2_k127_6437375_4 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 336.0
SRD2_k127_6437375_5 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000644 260.0
SRD2_k127_6437375_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000003833 185.0
SRD2_k127_6437375_7 Domain of unknown function (DUF1820) - - - 0.00000000000000000000000000000000000002108 153.0
SRD2_k127_6437375_8 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 0.00000000000000000000000000000000002 135.0
SRD2_k127_6437375_9 Type VI secretion K07169,K11894,K11913 - - 0.000000000000000000000000000001126 137.0
SRD2_k127_6505155_0 PEP-utilising enzyme, TIM barrel domain K01007 - 2.7.9.2 0.0 1182.0
SRD2_k127_6505155_1 Sugar (and other) transporter K08172 - - 1.363e-209 659.0
SRD2_k127_6505155_10 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 473.0
SRD2_k127_6505155_11 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000557 276.0
SRD2_k127_6505155_12 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006725 278.0
SRD2_k127_6505155_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007009 277.0
SRD2_k127_6505155_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005056 268.0
SRD2_k127_6505155_15 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008693 256.0
SRD2_k127_6505155_16 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000002146 233.0
SRD2_k127_6505155_17 PFAM Cold-shock protein, DNA-binding - - - 0.00000000000000000000000000000000000000000000000000001085 196.0
SRD2_k127_6505155_18 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000008807 180.0
SRD2_k127_6505155_19 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000001107 172.0
SRD2_k127_6505155_2 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 1.682e-198 628.0
SRD2_k127_6505155_20 - - - - 0.00000000000000000000002872 109.0
SRD2_k127_6505155_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 589.0
SRD2_k127_6505155_4 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 573.0
SRD2_k127_6505155_5 AAA ATPase, central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 559.0
SRD2_k127_6505155_6 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 529.0
SRD2_k127_6505155_7 3-beta hydroxysteroid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 520.0
SRD2_k127_6505155_8 glucan 1,4-alpha-glucosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 507.0
SRD2_k127_6505155_9 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 510.0
SRD2_k127_6555130_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 2.312e-198 659.0
SRD2_k127_6555130_1 aminotransferase K14260 - 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 482.0
SRD2_k127_6555130_10 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000004385 151.0
SRD2_k127_6555130_11 Rhomboid family - - - 0.000000000000000000000000002796 118.0
SRD2_k127_6555130_12 GspL periplasmic domain - - - 0.00000000000000000000000005286 123.0
SRD2_k127_6555130_13 General secretion pathway protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000000003402 119.0
SRD2_k127_6555130_14 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.0000000000000000002788 94.0
SRD2_k127_6555130_15 general secretion pathway protein K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000009226 91.0
SRD2_k127_6555130_16 type II secretion system protein N K02463 - - 0.0000000000000002371 89.0
SRD2_k127_6555130_17 Type II transport protein GspH K02457 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000004311 85.0
SRD2_k127_6555130_18 Electron transfer flavoprotein K03522 - - 0.00000000008497 70.0
SRD2_k127_6555130_19 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000839 48.0
SRD2_k127_6555130_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 442.0
SRD2_k127_6555130_3 electron transfer flavoprotein beta subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 346.0
SRD2_k127_6555130_4 transporter, permease K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 342.0
SRD2_k127_6555130_5 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 342.0
SRD2_k127_6555130_6 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 316.0
SRD2_k127_6555130_7 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 290.0
SRD2_k127_6555130_8 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000001738 274.0
SRD2_k127_6555130_9 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000001498 175.0
SRD2_k127_6570933_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1268.0
SRD2_k127_6570933_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 420.0
SRD2_k127_6570933_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000004501 203.0
SRD2_k127_6583035_0 PFAM PrkA AAA K07180 - - 1.572e-297 925.0
SRD2_k127_6583035_1 efflux protein, MATE family K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 416.0
SRD2_k127_6583035_10 - - - - 0.000000000000000000003628 95.0
SRD2_k127_6583035_11 Cysteine-rich CPXCG - - - 0.000000000001988 74.0
SRD2_k127_6583035_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000235 77.0
SRD2_k127_6583035_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 383.0
SRD2_k127_6583035_3 Hpt domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 326.0
SRD2_k127_6583035_4 TraB family - - - 0.000000000000000000000000000000000000000000000000000003132 204.0
SRD2_k127_6583035_5 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000009022 183.0
SRD2_k127_6583035_6 DUF218 domain - - - 0.00000000000000000000000000000000000000005836 161.0
SRD2_k127_6583035_7 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000003334 150.0
SRD2_k127_6583035_8 Chemotaxis phosphatase CheX K03409 - - 0.000000000000000000000000000000000002347 145.0
SRD2_k127_6583035_9 proteolysis - - - 0.000000000000000000000000000001534 136.0
SRD2_k127_6681026_0 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 546.0
SRD2_k127_6681026_1 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 371.0
SRD2_k127_6681026_2 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 341.0
SRD2_k127_6681026_3 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 319.0
SRD2_k127_6681026_4 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000001765 235.0
SRD2_k127_6681026_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001902 210.0
SRD2_k127_6681026_6 Translation initiation factor SUI1 K03113 - - 0.000000000000000000000004101 106.0
SRD2_k127_6681026_7 protein conserved in bacteria - - - 0.000000000000000000000005701 119.0
SRD2_k127_6681026_8 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000005389 100.0
SRD2_k127_6681026_9 ThiS family K03636 - - 0.00000000000000000003651 101.0
SRD2_k127_6974160_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 6.481e-245 768.0
SRD2_k127_6974160_1 Belongs to the malate synthase family K01638 - 2.3.3.9 1.695e-217 687.0
SRD2_k127_6974160_10 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003124 240.0
SRD2_k127_6974160_11 YXWGXW repeat (2 copies) - - - 0.000000000000000000000000000007282 132.0
SRD2_k127_6974160_2 Catalyzes the reversible formation of glyoxylate and succinate from isocitrate K01637 - 4.1.3.1 1.501e-210 662.0
SRD2_k127_6974160_3 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 536.0
SRD2_k127_6974160_4 Transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 528.0
SRD2_k127_6974160_5 e3 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 409.0
SRD2_k127_6974160_6 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 320.0
SRD2_k127_6974160_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006715 259.0
SRD2_k127_6974160_8 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008034 254.0
SRD2_k127_6974160_9 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000001407 240.0
SRD2_k127_697535_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 517.0
SRD2_k127_697535_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 476.0
SRD2_k127_697535_2 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 473.0
SRD2_k127_697535_3 Mg2 and Co2 transporter CorB - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 387.0
SRD2_k127_697535_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 289.0
SRD2_k127_697535_5 phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002507 279.0
SRD2_k127_697535_6 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 0.0000000000000000000000000000000000000000000000000001555 186.0
SRD2_k127_697535_7 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000853 185.0
SRD2_k127_697535_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000005203 122.0
SRD2_k127_697535_9 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001375 108.0
SRD2_k127_6988816_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 4.746e-299 927.0
SRD2_k127_6988816_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - 3.316e-213 670.0
SRD2_k127_6988816_2 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 605.0
SRD2_k127_6988816_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 595.0
SRD2_k127_6988816_4 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 302.0
SRD2_k127_6988816_5 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007934 258.0
SRD2_k127_6988816_6 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000001279 239.0
SRD2_k127_6988816_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000000000002126 88.0
SRD2_k127_6994428_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0 1105.0
SRD2_k127_6994428_1 Dienelactone hydrolase family - - - 0.0 1055.0
SRD2_k127_6994428_10 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 494.0
SRD2_k127_6994428_11 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 499.0
SRD2_k127_6994428_12 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 488.0
SRD2_k127_6994428_13 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 469.0
SRD2_k127_6994428_14 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 474.0
SRD2_k127_6994428_15 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 415.0
SRD2_k127_6994428_16 Major Facilitator K03762 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 434.0
SRD2_k127_6994428_17 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 397.0
SRD2_k127_6994428_18 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 381.0
SRD2_k127_6994428_19 hydroxyacylglutathione hydrolase activity K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 380.0
SRD2_k127_6994428_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 8.632e-283 885.0
SRD2_k127_6994428_20 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 371.0
SRD2_k127_6994428_21 COG1994 Zn-dependent proteases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 363.0
SRD2_k127_6994428_22 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 353.0
SRD2_k127_6994428_23 signal transduction histidine kinase K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 332.0
SRD2_k127_6994428_24 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002175 268.0
SRD2_k127_6994428_25 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002549 271.0
SRD2_k127_6994428_26 Protein of unknown function (DUF2167) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007167 256.0
SRD2_k127_6994428_27 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002248 263.0
SRD2_k127_6994428_28 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000002711 254.0
SRD2_k127_6994428_29 YXWGXW repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000008845 235.0
SRD2_k127_6994428_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.743e-265 841.0
SRD2_k127_6994428_30 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000001149 231.0
SRD2_k127_6994428_31 Domain of unknown function (DUF3291) - - - 0.000000000000000000000000000000000000000000000000000000000001141 218.0
SRD2_k127_6994428_32 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000003404 218.0
SRD2_k127_6994428_33 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 0.000000000000000000000000000000000000000000000000000001033 199.0
SRD2_k127_6994428_34 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000004921 176.0
SRD2_k127_6994428_35 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000004554 147.0
SRD2_k127_6994428_36 thioredoxin domain - - - 0.0000000000000000000000000000000356 134.0
SRD2_k127_6994428_37 Conserved Protein - - - 0.000000000000000000000000002592 119.0
SRD2_k127_6994428_38 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000000000000000000000004534 117.0
SRD2_k127_6994428_39 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000002565 109.0
SRD2_k127_6994428_4 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 1.428e-247 771.0
SRD2_k127_6994428_40 - - - - 0.000000000000000000002228 98.0
SRD2_k127_6994428_41 Domain of unknown function (DUF4124) - - - 0.00000000000000000021 97.0
SRD2_k127_6994428_42 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000007214 83.0
SRD2_k127_6994428_43 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001373 74.0
SRD2_k127_6994428_44 Tetratricopeptide repeat - - - 0.00000000002368 72.0
SRD2_k127_6994428_45 RHS Repeat - - - 0.00000001309 63.0
SRD2_k127_6994428_46 Membrane protein implicated in regulation of membrane protease activity K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000006707 57.0
SRD2_k127_6994428_48 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 0.0001635 54.0
SRD2_k127_6994428_5 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.481e-212 683.0
SRD2_k127_6994428_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 9.467e-194 614.0
SRD2_k127_6994428_7 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 593.0
SRD2_k127_6994428_8 PFAM TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 572.0
SRD2_k127_6994428_9 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 499.0
SRD2_k127_7012606_0 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 2.418e-219 699.0
SRD2_k127_7012606_1 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 362.0
SRD2_k127_7012606_2 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005773 273.0
SRD2_k127_7012606_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005194 254.0
SRD2_k127_7012606_4 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000009455 228.0
SRD2_k127_7012606_5 Redoxin domain protein - - - 0.000000000000000000000000000000000000007235 152.0
SRD2_k127_7012606_6 Transcription elongation factor - - - 0.00000000000000000000000000000000008276 145.0
SRD2_k127_7012606_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000001589 111.0
SRD2_k127_7049333_0 CoA-binding domain protein K09181 - - 0.0 1140.0
SRD2_k127_7049333_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0 1056.0
SRD2_k127_7049333_10 D-amino acid dehydrogenase K00285 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0008718,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019478,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055114,GO:0055130,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 344.0
SRD2_k127_7049333_11 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 345.0
SRD2_k127_7049333_12 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 319.0
SRD2_k127_7049333_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 325.0
SRD2_k127_7049333_14 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 317.0
SRD2_k127_7049333_15 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 313.0
SRD2_k127_7049333_16 SMART zinc finger, CDGSH-type domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 316.0
SRD2_k127_7049333_17 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 298.0
SRD2_k127_7049333_18 - - - - 0.00000000004264 67.0
SRD2_k127_7049333_19 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000008417 56.0
SRD2_k127_7049333_2 PFAM AMP-dependent synthetase and ligase K00666 - - 3.407e-300 926.0
SRD2_k127_7049333_20 Periplasmic or secreted lipoprotein K04065 - - 0.00005496 50.0
SRD2_k127_7049333_21 bacterial OsmY and nodulation domain K04065 - - 0.0001355 51.0
SRD2_k127_7049333_22 BON domain K04065 - - 0.000191 50.0
SRD2_k127_7049333_3 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 6.642e-243 756.0
SRD2_k127_7049333_4 Amidohydrolase family K06015 - 3.5.1.81 1.506e-239 766.0
SRD2_k127_7049333_5 Spermidine putrescine ABC transporter substrate-binding protein K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 556.0
SRD2_k127_7049333_6 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 509.0
SRD2_k127_7049333_7 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 421.0
SRD2_k127_7049333_8 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 421.0
SRD2_k127_7049333_9 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 373.0
SRD2_k127_7050008_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 544.0
SRD2_k127_7050008_1 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 473.0
SRD2_k127_7050008_2 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000702 254.0
SRD2_k127_7050008_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000001621 199.0
SRD2_k127_7050008_4 Iron--sulfur cluster insertion protein erpA K15724 - - 0.000000000000000000000000000000000000000000000004692 174.0
SRD2_k127_7050008_5 cell shape determination - - - 0.000000000000000000000000006782 114.0
SRD2_k127_7050008_6 - - - - 0.00000000000002003 84.0
SRD2_k127_7066585_0 TonB-dependent Receptor Plug Domain - - - 7.1e-233 751.0
SRD2_k127_7066585_1 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 582.0
SRD2_k127_7066585_2 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 414.0
SRD2_k127_7066585_3 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 415.0
SRD2_k127_7066585_4 receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007021 347.0
SRD2_k127_7066585_5 GGDEF domain - - - 0.000000000000000000000000000000000000000001866 175.0
SRD2_k127_7066585_6 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000009592 124.0
SRD2_k127_7066585_7 Phosphoglycerate mutase family - - - 0.00000002461 63.0
SRD2_k127_7066585_8 Chorismate mutase K00014,K00891,K04092,K04516 - 1.1.1.25,2.7.1.71,5.4.99.5 0.00004156 46.0
SRD2_k127_7087341_0 Binding-protein-dependent transport systems inner membrane component K02050 - - 2.322e-220 698.0
SRD2_k127_7087341_1 C-terminal AAA-associated domain K02049 - - 1.634e-196 621.0
SRD2_k127_7087341_2 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000006396 221.0
SRD2_k127_7129075_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1257.0
SRD2_k127_7129075_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 424.0
SRD2_k127_7129075_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000001267 227.0
SRD2_k127_7129075_3 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000298 224.0
SRD2_k127_7129075_4 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000002125 210.0
SRD2_k127_7129075_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000418 121.0
SRD2_k127_7129075_6 Putative regulatory protein - - - 0.00000000000000000000000364 108.0
SRD2_k127_7193221_0 Domain of unknown function (DUF1794) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 340.0
SRD2_k127_7193221_1 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 344.0
SRD2_k127_7193221_2 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 308.0
SRD2_k127_7193221_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 314.0
SRD2_k127_7193221_4 Uncharacterized protein conserved in bacteria (DUF2090) K03338 - 2.7.1.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000006731 258.0
SRD2_k127_7193221_5 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004017 253.0
SRD2_k127_7193221_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004408 244.0
SRD2_k127_7193221_7 - - - - 0.0000000000000000000000000000000000000000000000000003536 196.0
SRD2_k127_7193221_8 MAPEG family - - - 0.0000000000000000000000000000000008 135.0
SRD2_k127_7278187_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.0 1037.0
SRD2_k127_7278187_1 peptidase K01415,K07386 - 3.4.24.71 3.328e-279 874.0
SRD2_k127_7278187_10 Binding-protein-dependent transport system inner membrane component K02050,K15552,K15554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 386.0
SRD2_k127_7278187_11 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 397.0
SRD2_k127_7278187_12 Drug metabolite transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 383.0
SRD2_k127_7278187_13 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 368.0
SRD2_k127_7278187_14 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 353.0
SRD2_k127_7278187_15 Abc transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 346.0
SRD2_k127_7278187_16 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007922 276.0
SRD2_k127_7278187_17 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000581 270.0
SRD2_k127_7278187_18 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001004 269.0
SRD2_k127_7278187_19 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009415 273.0
SRD2_k127_7278187_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 514.0
SRD2_k127_7278187_20 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009132 233.0
SRD2_k127_7278187_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06991 - - 0.000000000000000000000000000000000000000000000000000000000000009548 221.0
SRD2_k127_7278187_22 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000001711 201.0
SRD2_k127_7278187_23 S1/P1 Nuclease - - - 0.0000000000000000000000000000000000000000000000000006841 195.0
SRD2_k127_7278187_24 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000001823 165.0
SRD2_k127_7278187_25 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000002242 171.0
SRD2_k127_7278187_26 Cytochrome c - - - 0.000000000000000000000000000000000000000000644 160.0
SRD2_k127_7278187_27 Outer membrane receptor - - - 0.000000000000000000000000000000000000000004874 162.0
SRD2_k127_7278187_28 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000008049 156.0
SRD2_k127_7278187_29 Putative zinc-finger - - - 0.00000000000000000000000000000000000003299 153.0
SRD2_k127_7278187_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 475.0
SRD2_k127_7278187_30 Nitrile hydratase beta subunit - - - 0.000000000000000000000000000000000002444 141.0
SRD2_k127_7278187_31 Tyrosine phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000002173 136.0
SRD2_k127_7278187_32 COG3121 P pilus assembly protein, chaperone PapD K07346 - - 0.0000000000000000000000000000002595 133.0
SRD2_k127_7278187_33 negative regulation of translational initiation - - - 0.0000000000000000000000000001939 123.0
SRD2_k127_7278187_34 redox protein, regulator of disulfide bond formation K07397 - - 0.000000000000000000000003659 107.0
SRD2_k127_7278187_35 Spore Coat Protein - - - 0.0000000000000000000002547 103.0
SRD2_k127_7278187_36 Spore Coat Protein U domain - - - 0.00000000000000000002577 97.0
SRD2_k127_7278187_37 Secreted protein - - - 0.0000000000000552 80.0
SRD2_k127_7278187_38 - - - - 0.0001075 47.0
SRD2_k127_7278187_4 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 484.0
SRD2_k127_7278187_5 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 470.0
SRD2_k127_7278187_6 Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 437.0
SRD2_k127_7278187_7 Outer membrane usher protein K07347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 439.0
SRD2_k127_7278187_8 Belongs to the DapA family K01714,K21062 - 3.5.4.22,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 407.0
SRD2_k127_7278187_9 Belongs to the proline racemase family K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 409.0
SRD2_k127_7285089_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 4.304e-266 831.0
SRD2_k127_7285089_1 GabA permease K11735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 554.0
SRD2_k127_7285089_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 434.0
SRD2_k127_7285089_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000138 301.0
SRD2_k127_7285089_4 Transcriptional regulator K19333 - - 0.0000000000000000000000000000000000000000000000000000000000000000001094 239.0
SRD2_k127_7285089_5 Haloacid dehalogenase-like hydrolase K05306 - 3.11.1.1 0.000000000004755 69.0
SRD2_k127_7299729_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1515.0
SRD2_k127_7299729_1 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K07303 - 1.3.99.16 5.07e-252 797.0
SRD2_k127_7299729_10 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 334.0
SRD2_k127_7299729_11 nitrite transmembrane transporter activity K08218,K08223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 317.0
SRD2_k127_7299729_12 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008161 268.0
SRD2_k127_7299729_13 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005018 257.0
SRD2_k127_7299729_14 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000005523 279.0
SRD2_k127_7299729_15 Receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003008 282.0
SRD2_k127_7299729_16 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000003233 243.0
SRD2_k127_7299729_17 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000009327 237.0
SRD2_k127_7299729_18 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000006363 231.0
SRD2_k127_7299729_19 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000002077 225.0
SRD2_k127_7299729_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 539.0
SRD2_k127_7299729_20 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000184 198.0
SRD2_k127_7299729_21 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000001638 171.0
SRD2_k127_7299729_22 GGDEF domain K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000008183 174.0
SRD2_k127_7299729_23 Rieske 2Fe-2S - - - 0.0000000000000000000000001969 115.0
SRD2_k127_7299729_24 - - - - 0.0000000000008865 73.0
SRD2_k127_7299729_25 Domain of unknown function (DUF4124) - - - 0.000000000005078 74.0
SRD2_k127_7299729_26 - - - - 0.000004329 51.0
SRD2_k127_7299729_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 529.0
SRD2_k127_7299729_4 peptidase S10 serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 522.0
SRD2_k127_7299729_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 430.0
SRD2_k127_7299729_6 hydrolase activity, acting on ester bonds K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 401.0
SRD2_k127_7299729_7 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 360.0
SRD2_k127_7299729_8 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 359.0
SRD2_k127_7299729_9 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 353.0
SRD2_k127_7348230_0 Type II secretory pathway, component HofQ K02666 - - 2.329e-198 641.0
SRD2_k127_7348230_1 dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 505.0
SRD2_k127_7348230_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 418.0
SRD2_k127_7348230_3 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000004291 211.0
SRD2_k127_7348230_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000009022 183.0
SRD2_k127_7348230_5 PFAM Fimbrial assembly K02663 - - 0.000000000000000000000000000000000000000007237 161.0
SRD2_k127_7348230_6 pilus assembly protein pilp K02665 - - 0.00000000000000000000000000000000000004181 158.0
SRD2_k127_7348230_7 sister chromatid segregation - - - 0.0001427 48.0
SRD2_k127_7497480_0 OmpA family - - - 0.0 1799.0
SRD2_k127_7497480_1 MMPL family - - - 0.0 1733.0
SRD2_k127_7497480_10 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - 1.585e-216 708.0
SRD2_k127_7497480_11 Tetratricopeptide repeat - - - 3.264e-211 673.0
SRD2_k127_7497480_12 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 5.183e-211 672.0
SRD2_k127_7497480_13 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 521.0
SRD2_k127_7497480_14 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 561.0
SRD2_k127_7497480_15 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 504.0
SRD2_k127_7497480_16 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 496.0
SRD2_k127_7497480_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 493.0
SRD2_k127_7497480_18 thiamine metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 481.0
SRD2_k127_7497480_19 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 487.0
SRD2_k127_7497480_2 Hemerythrin HHE cation binding domain K01534 - 3.6.3.3,3.6.3.5 0.0 1075.0
SRD2_k127_7497480_20 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 473.0
SRD2_k127_7497480_21 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 474.0
SRD2_k127_7497480_22 of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 455.0
SRD2_k127_7497480_23 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 449.0
SRD2_k127_7497480_24 Polysaccharide deacetylase K01452 - 3.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 391.0
SRD2_k127_7497480_25 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 383.0
SRD2_k127_7497480_26 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 380.0
SRD2_k127_7497480_27 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 390.0
SRD2_k127_7497480_28 (ABC) transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 355.0
SRD2_k127_7497480_29 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 356.0
SRD2_k127_7497480_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.467e-317 984.0
SRD2_k127_7497480_30 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 351.0
SRD2_k127_7497480_31 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 351.0
SRD2_k127_7497480_32 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 339.0
SRD2_k127_7497480_33 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 316.0
SRD2_k127_7497480_34 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 313.0
SRD2_k127_7497480_35 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 314.0
SRD2_k127_7497480_36 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001151 297.0
SRD2_k127_7497480_37 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000178 252.0
SRD2_k127_7497480_38 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004291 246.0
SRD2_k127_7497480_39 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000004104 232.0
SRD2_k127_7497480_4 COG2217 Cation transport ATPase K17686 - 3.6.3.54 2.181e-308 961.0
SRD2_k127_7497480_40 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001786 229.0
SRD2_k127_7497480_41 - - - - 0.000000000000000000000000000000000000000000000000000000000001511 214.0
SRD2_k127_7497480_42 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000003343 218.0
SRD2_k127_7497480_43 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001905 201.0
SRD2_k127_7497480_44 methylamine metabolic process K15977 - - 0.00000000000000000000000000000000000000000000000000001484 193.0
SRD2_k127_7497480_45 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000001302 191.0
SRD2_k127_7497480_46 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000002087 198.0
SRD2_k127_7497480_47 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000003737 180.0
SRD2_k127_7497480_48 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000008528 171.0
SRD2_k127_7497480_49 YCII-related domain - - - 0.00000000000000000000000000000000000000000004699 164.0
SRD2_k127_7497480_5 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.004e-286 892.0
SRD2_k127_7497480_50 CheR methyltransferase, all-alpha domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000001485 157.0
SRD2_k127_7497480_51 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000001202 144.0
SRD2_k127_7497480_52 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000004731 143.0
SRD2_k127_7497480_53 - - - - 0.00000000000000000000000000000000007589 149.0
SRD2_k127_7497480_54 Beta-Ig-H3 fasciclin - - - 0.00000000000000000000000000000000008993 141.0
SRD2_k127_7497480_55 Tetratricopeptide repeat - - - 0.000000000000000000000000000000002732 138.0
SRD2_k127_7497480_56 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000002674 128.0
SRD2_k127_7497480_57 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000001708 135.0
SRD2_k127_7497480_58 helix_turn_helix, mercury resistance K19591 - - 0.0000000000000000000000000000002958 126.0
SRD2_k127_7497480_59 transcriptional regulators K03892 - - 0.000000000000000000000000000003286 124.0
SRD2_k127_7497480_6 Tetratricopeptide repeat - - - 3.661e-280 907.0
SRD2_k127_7497480_60 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000002657 119.0
SRD2_k127_7497480_61 - - - - 0.00000000000000000000000000738 114.0
SRD2_k127_7497480_62 Copper resistance protein D K07245 - - 0.0000000000000000000001473 108.0
SRD2_k127_7497480_63 PAS domain - - - 0.00000000000000000001416 96.0
SRD2_k127_7497480_64 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741,K03892 - 1.20.4.1 0.00000000000000000007159 99.0
SRD2_k127_7497480_65 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.0000000000000000001315 94.0
SRD2_k127_7497480_66 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000000001476 92.0
SRD2_k127_7497480_67 - - - - 0.0000000000001515 78.0
SRD2_k127_7497480_68 tau-protein kinase activity K08798 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004679,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006325,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010646,GO:0010648,GO:0016043,GO:0016301,GO:0016310,GO:0016569,GO:0016570,GO:0016572,GO:0016740,GO:0016772,GO:0016773,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0023051,GO:0023052,GO:0023057,GO:0031588,GO:0031667,GO:0031668,GO:0031669,GO:0032006,GO:0032007,GO:0032991,GO:0033554,GO:0035173,GO:0035174,GO:0035404,GO:0035556,GO:0036211,GO:0042149,GO:0042594,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051276,GO:0051716,GO:0061695,GO:0065007,GO:0071496,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1902494,GO:1902531,GO:1902532,GO:1902911,GO:1990234 2.7.11.1 0.0000000000003046 83.0
SRD2_k127_7497480_69 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000001544 71.0
SRD2_k127_7497480_7 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 1.651e-244 781.0
SRD2_k127_7497480_70 - - - - 0.000000000002743 72.0
SRD2_k127_7497480_71 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000001711 66.0
SRD2_k127_7497480_72 CopC domain K07156 - - 0.0000000001283 66.0
SRD2_k127_7497480_8 TonB-dependent Receptor Plug Domain - - - 3.586e-238 766.0
SRD2_k127_7497480_9 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.215e-219 706.0
SRD2_k127_7499362_0 PFAM GMC oxidoreductase - - - 4.197e-307 949.0
SRD2_k127_7499362_1 Glutaryl-7-ACA acylase K06978 - - 1.167e-299 939.0
SRD2_k127_7499362_10 peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01322 - 3.4.21.26 7.675e-204 659.0
SRD2_k127_7499362_11 Putative 2OG-Fe(II) oxygenase - - - 1.587e-202 649.0
SRD2_k127_7499362_12 Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system K01194 - 3.2.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 601.0
SRD2_k127_7499362_13 Nucleoside H+ symporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 567.0
SRD2_k127_7499362_14 Major Facilitator Superfamily K02429 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 556.0
SRD2_k127_7499362_15 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 513.0
SRD2_k127_7499362_16 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 377.0
SRD2_k127_7499362_17 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 346.0
SRD2_k127_7499362_18 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000241 282.0
SRD2_k127_7499362_19 phenazine biosynthesis protein PhzF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005788 280.0
SRD2_k127_7499362_2 trimethylamine methyltransferase K14083 - 2.1.1.250 1.737e-272 845.0
SRD2_k127_7499362_20 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002296 240.0
SRD2_k127_7499362_21 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000279 242.0
SRD2_k127_7499362_22 Gluconate 2-dehydrogenase subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000002262 234.0
SRD2_k127_7499362_23 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000003223 227.0
SRD2_k127_7499362_24 methylamine dehydrogenase accessory protein MauD - - - 0.00000000000000000000000000000000000000000000000000000000001868 218.0
SRD2_k127_7499362_25 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000002031 187.0
SRD2_k127_7499362_26 redox protein, regulator of disulfide bond formation K07397 - - 0.00000000000000000000000000000000000000000000001024 175.0
SRD2_k127_7499362_27 HutD K09975 - - 0.000000000000000000000000000000000004363 148.0
SRD2_k127_7499362_28 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000136 124.0
SRD2_k127_7499362_29 - - - - 0.0000000000000000000000000007168 119.0
SRD2_k127_7499362_3 Glycosyl hydrolase family 65 central catalytic domain - - - 1.559e-267 844.0
SRD2_k127_7499362_30 Methylamine utilisation protein MauE - - - 0.00000000000000000000000009171 113.0
SRD2_k127_7499362_31 protein TIM barrel - - - 0.0000000000000000000000001285 121.0
SRD2_k127_7499362_32 Polymer-forming cytoskeletal - - - 0.000000000000000000000284 100.0
SRD2_k127_7499362_33 Polymer-forming cytoskeletal - - - 0.0000000000000005154 85.0
SRD2_k127_7499362_34 Recombinase zinc beta ribbon domain - - - 0.00001184 51.0
SRD2_k127_7499362_4 PFAM Glycoside hydrolase, clan GH-D - - - 1.008e-262 828.0
SRD2_k127_7499362_5 - - - - 4.493e-224 742.0
SRD2_k127_7499362_6 Beta-L-arabinofuranosidase, GH127 K09955 - - 3.149e-222 734.0
SRD2_k127_7499362_7 Dehydrogenase - - - 1.284e-221 704.0
SRD2_k127_7499362_8 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.941e-220 707.0
SRD2_k127_7499362_9 TonB-dependent receptor - - - 1.116e-214 695.0
SRD2_k127_7813195_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 0.0 1113.0
SRD2_k127_7813195_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 416.0
SRD2_k127_7813195_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 309.0
SRD2_k127_7813195_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000002062 118.0
SRD2_k127_7813195_4 Protein of unknown function (DUF1249) K09920 - - 0.0000000000000000000006124 109.0
SRD2_k127_7898444_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.852e-238 741.0
SRD2_k127_7898444_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.047e-224 701.0
SRD2_k127_7898444_10 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001769 247.0
SRD2_k127_7898444_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000001979 166.0
SRD2_k127_7898444_12 Preprotein translocase SecG subunit K03075 - - 0.00000000000000001053 87.0
SRD2_k127_7898444_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 547.0
SRD2_k127_7898444_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 523.0
SRD2_k127_7898444_4 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 324.0
SRD2_k127_7898444_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 299.0
SRD2_k127_7898444_6 anaphase-promoting complex binding K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009955 329.0
SRD2_k127_7898444_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 314.0
SRD2_k127_7898444_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001961 306.0
SRD2_k127_7898444_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002355 256.0
SRD2_k127_7958059_0 TIGRFAM FeS assembly protein SufB K09014 - - 6.237e-254 797.0
SRD2_k127_7958059_1 serine dehydratase beta chain K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 559.0
SRD2_k127_7958059_10 FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000002053 208.0
SRD2_k127_7958059_11 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000001513 178.0
SRD2_k127_7958059_12 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000001614 155.0
SRD2_k127_7958059_13 PFAM PhoH family protein K07175 - - 0.00000000000000000000000000000000000000251 146.0
SRD2_k127_7958059_14 transcriptional regulator - - - 0.000000000000000000000000000000000006783 141.0
SRD2_k127_7958059_15 PFAM toluene tolerance K07323 - - 0.00000000000000000000000000000001399 136.0
SRD2_k127_7958059_16 Belongs to the HSP15 family K04762 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000002545 113.0
SRD2_k127_7958059_17 Histidine phosphatase superfamily (branch 1) K08296 - - 0.00000000000000000000000007794 115.0
SRD2_k127_7958059_18 PFAM Rieske 2Fe-2S K05710 - - 0.0000000000000000000000001765 109.0
SRD2_k127_7958059_19 STAS domain K07122 - - 0.00000007632 63.0
SRD2_k127_7958059_2 Cysteine desulfurase K01766,K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 534.0
SRD2_k127_7958059_3 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 431.0
SRD2_k127_7958059_4 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 364.0
SRD2_k127_7958059_5 PFAM ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 341.0
SRD2_k127_7958059_6 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004453 278.0
SRD2_k127_7958059_7 ABC transporter permease K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007897 269.0
SRD2_k127_7958059_8 TIGRFAM FeS assembly SUF system protein SufT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001255 251.0
SRD2_k127_7958059_9 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000000000000005231 205.0
SRD2_k127_7962924_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.064e-250 782.0
SRD2_k127_7962924_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.161e-244 768.0
SRD2_k127_7962924_10 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 353.0
SRD2_k127_7962924_11 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000003994 269.0
SRD2_k127_7962924_12 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000008424 262.0
SRD2_k127_7962924_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000002382 246.0
SRD2_k127_7962924_14 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.00000000000000000000000000000000000000000000000000000003225 216.0
SRD2_k127_7962924_15 Belongs to the DnaA family. HdA subfamily K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000006114 182.0
SRD2_k127_7962924_16 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000003004 157.0
SRD2_k127_7962924_17 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000002072 160.0
SRD2_k127_7962924_18 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000003657 148.0
SRD2_k127_7962924_19 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000007778 151.0
SRD2_k127_7962924_2 serine threonine protein kinase K12132 - 2.7.11.1 1.989e-201 657.0
SRD2_k127_7962924_20 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000001524 87.0
SRD2_k127_7962924_21 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000001575 92.0
SRD2_k127_7962924_22 Protein of unknown function (DUF3108) - - - 0.00000000000000005271 90.0
SRD2_k127_7962924_3 Ferritin-like K20087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 609.0
SRD2_k127_7962924_4 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 587.0
SRD2_k127_7962924_5 PFAM Type II secretion system protein E - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 520.0
SRD2_k127_7962924_6 AIR synthase related protein domain protein K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 463.0
SRD2_k127_7962924_7 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 462.0
SRD2_k127_7962924_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 426.0
SRD2_k127_7962924_9 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 413.0
SRD2_k127_7964128_0 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 428.0
SRD2_k127_7964128_1 Major facilitator Superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 414.0
SRD2_k127_7964128_2 secretion protein HlyD K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 379.0
SRD2_k127_7964128_3 PFAM amino acid permease-associated region K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 364.0
SRD2_k127_7964128_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 360.0
SRD2_k127_7964128_5 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000001625 161.0
SRD2_k127_7964128_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000001231 134.0
SRD2_k127_7964128_7 Domain of unknown function (DUF4915) - - - 0.00000000000000000000001966 110.0
SRD2_k127_847497_0 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1015.0
SRD2_k127_847497_1 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 477.0
SRD2_k127_847497_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000009076 265.0
SRD2_k127_847497_3 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000001556 194.0
SRD2_k127_847497_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000004271 163.0
SRD2_k127_847497_5 Type II secretion system protein C - - - 0.00000000000000000000000000000000000006015 156.0
SRD2_k127_847497_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000001775 130.0
SRD2_k127_893070_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1266.0
SRD2_k127_893070_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 364.0
SRD2_k127_893070_2 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001861 284.0
SRD2_k127_893070_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10715 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000005532 226.0
SRD2_k127_893070_4 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000002727 200.0
SRD2_k127_893070_5 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000001571 141.0
SRD2_k127_893070_6 - - - - 0.0000000000000000002503 92.0
SRD2_k127_893070_7 Peptidoglycan-binding protein, CsiV - - - 0.000000005347 66.0
SRD2_k127_95336_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.175e-278 863.0
SRD2_k127_95336_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 457.0
SRD2_k127_95336_10 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000003062 160.0
SRD2_k127_95336_11 Integral membrane protein (DUF2244) - - - 0.0000000000000000000003015 106.0
SRD2_k127_95336_12 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000007333 100.0
SRD2_k127_95336_13 Protein of unknown function (DUF2909) - - - 0.000000005918 61.0
SRD2_k127_95336_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 392.0
SRD2_k127_95336_3 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 374.0
SRD2_k127_95336_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 324.0
SRD2_k127_95336_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 306.0
SRD2_k127_95336_6 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 289.0
SRD2_k127_95336_7 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000001194 204.0
SRD2_k127_95336_8 cytochrome c oxidase assembly protein K02258 - - 0.000000000000000000000000000000000000000000005096 170.0
SRD2_k127_95336_9 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000003532 157.0