Overview

ID MAG03602
Name SX1_bin.1
Sample SMP0091
Taxonomy
Kingdom Archaea
Phylum Hydrothermarchaeota
Class Hydrothermarchaeia
Order Hydrothermarchaeales
Family JAZFTJ01
Genus
Species
Assembly information
Completeness (%) 95.95
Contamination (%) 0.53
GC content (%) 59.0
N50 (bp) 15,725
Genome size (bp) 1,305,677

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1282

Gene name Description KEGG GOs EC E-value Score Sequence
SX1_k127_1042078_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.651e-265 829.0
SX1_k127_1042078_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.267e-239 746.0
SX1_k127_1042078_10 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000001141 82.0
SX1_k127_1042078_11 IMP dehydrogenase activity - - - 0.00002056 58.0
SX1_k127_1042078_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 316.0
SX1_k127_1042078_3 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000363 247.0
SX1_k127_1042078_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000001856 235.0
SX1_k127_1042078_5 Belongs to the UPF0216 family K09737 - - 0.000000000000000000000000008606 115.0
SX1_k127_1042078_6 Peptidase M50 - - - 0.000000000000000000000008978 119.0
SX1_k127_1042078_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.000000000000000000001118 97.0
SX1_k127_1042078_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000003161 102.0
SX1_k127_1042078_9 Subtilase family K01183,K01337,K14645 - 3.2.1.14,3.4.21.50 0.000000000000000008446 98.0
SX1_k127_1091644_0 helix_turn_helix ASNC type K03718 - - 0.000000000006152 76.0
SX1_k127_1091644_1 Homeodomain-like domain K03718 - - 0.00000000008654 72.0
SX1_k127_1091644_2 methyltransferase - - - 0.000000001873 65.0
SX1_k127_1091644_3 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0006981 51.0
SX1_k127_1126984_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000001684 185.0
SX1_k127_1126984_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000001827 180.0
SX1_k127_1126984_2 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.0000000000000000006305 95.0
SX1_k127_1184924_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 3.948e-283 888.0
SX1_k127_1184924_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 9.986e-215 683.0
SX1_k127_1184924_10 domain protein K03698 - - 0.000000000000000000000000000000000000000000000000000000000000001028 230.0
SX1_k127_1184924_11 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000005075 214.0
SX1_k127_1184924_12 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000002803 182.0
SX1_k127_1184924_13 V-type ATP synthase subunit I K02123 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006885,GO:0007035,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019725,GO:0019829,GO:0019899,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0045851,GO:0046034,GO:0046390,GO:0046483,GO:0046961,GO:0048878,GO:0050801,GO:0051117,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0055086,GO:0065007,GO:0065008,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000002566 186.0
SX1_k127_1184924_14 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000001517 138.0
SX1_k127_1184924_15 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000001032 130.0
SX1_k127_1184924_16 family protein, PEP-CTERM locus subfamily - - - 0.00000000000000000001838 102.0
SX1_k127_1184924_17 Adenylate cyclase K05873 - 4.6.1.1 0.0000000000000001563 86.0
SX1_k127_1184924_18 CBS domain - - - 0.00000000000009157 77.0
SX1_k127_1184924_19 PFAM UspA domain protein K06149 - - 0.00000000002707 70.0
SX1_k127_1184924_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 5.284e-210 660.0
SX1_k127_1184924_20 - - - - 0.00000898 54.0
SX1_k127_1184924_21 PRC-barrel domain - - - 0.0001352 52.0
SX1_k127_1184924_22 transcriptional K07729 - - 0.0007884 49.0
SX1_k127_1184924_3 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 569.0
SX1_k127_1184924_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 417.0
SX1_k127_1184924_5 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 386.0
SX1_k127_1184924_6 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 377.0
SX1_k127_1184924_7 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 319.0
SX1_k127_1184924_8 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 316.0
SX1_k127_1184924_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001371 275.0
SX1_k127_1209329_0 PFAM PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 402.0
SX1_k127_1209329_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001233 271.0
SX1_k127_1209329_2 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000009853 236.0
SX1_k127_1209329_3 binds to the 23S rRNA K02929 - - 0.000000000000000000000000002637 117.0
SX1_k127_1209329_4 PFAM Ribosomal protein S27E K02978 - - 0.00000000000000001892 83.0
SX1_k127_1209329_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000008565 72.0
SX1_k127_1209329_6 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000003078 64.0
SX1_k127_1209329_7 protein conserved in archaea K09723 - - 0.0000000000497 70.0
SX1_k127_1222523_0 small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 439.0
SX1_k127_1222523_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000000000000000008154 191.0
SX1_k127_1222523_2 Roadblock LC7 family protein K07131 - - 0.000001696 50.0
SX1_k127_1267140_0 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 541.0
SX1_k127_1267140_1 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 490.0
SX1_k127_1267140_10 Transcriptional regulator, PadR-like family - - - 0.0000007004 55.0
SX1_k127_1267140_2 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 446.0
SX1_k127_1267140_3 PFAM Sulphate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 362.0
SX1_k127_1267140_4 PFAM ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 330.0
SX1_k127_1267140_5 Predicted permease K07089 - - 0.00000000000000000000000001138 110.0
SX1_k127_1267140_6 Putative Fe-S cluster - - - 0.000000000000000000000002111 108.0
SX1_k127_1267140_7 Predicted permease - - - 0.000000000000000000000006593 116.0
SX1_k127_1271370_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 535.0
SX1_k127_1271370_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000615 142.0
SX1_k127_1277719_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 461.0
SX1_k127_1277719_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 305.0
SX1_k127_1277719_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 292.0
SX1_k127_1277719_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000006603 166.0
SX1_k127_1277719_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000636 154.0
SX1_k127_1277719_5 PFAM phosphatidate cytidylyltransferase - - - 0.000000000000000000000003101 110.0
SX1_k127_1277719_6 KIP1-like protein K20283 GO:0001101,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005856,GO:0005886,GO:0006950,GO:0006970,GO:0008150,GO:0009507,GO:0009536,GO:0009628,GO:0009719,GO:0009725,GO:0009737,GO:0009787,GO:0009789,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010646,GO:0010647,GO:0016020,GO:0023051,GO:0023056,GO:0031090,GO:0032386,GO:0032870,GO:0032879,GO:0032880,GO:0033157,GO:0033993,GO:0042221,GO:0042306,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046822,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051223,GO:0051716,GO:0060341,GO:0065007,GO:0070201,GO:0070887,GO:0071215,GO:0071229,GO:0071310,GO:0071396,GO:0071495,GO:0071944,GO:0090087,GO:0097305,GO:0097306,GO:0098588,GO:0098805,GO:1900180,GO:1901419,GO:1901421,GO:1901700,GO:1901701,GO:1903827,GO:1904589,GO:1905957,GO:1905959 - 0.0001081 53.0
SX1_k127_1369287_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 387.0
SX1_k127_1369287_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 391.0
SX1_k127_1426674_0 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000001075 234.0
SX1_k127_1426674_1 - - - - 0.0000000000000000000000000002536 123.0
SX1_k127_1426674_2 Transglutaminase-like superfamily - - - 0.00000000001259 77.0
SX1_k127_148257_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 604.0
SX1_k127_148257_1 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005295 276.0
SX1_k127_148257_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704,K16793 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.114,4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000005377 231.0
SX1_k127_148257_3 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000002111 175.0
SX1_k127_148257_4 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.00000000001677 66.0
SX1_k127_1497749_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 304.0
SX1_k127_1497749_1 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000006819 96.0
SX1_k127_1497749_2 Phospholipase D Transphosphatidylase K06131,K06132,K06915 - - 0.000003135 57.0
SX1_k127_1499284_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1608.0
SX1_k127_1499284_1 ERCC4 domain K10896 - - 1.263e-204 660.0
SX1_k127_1499284_10 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000000000000001061 204.0
SX1_k127_1499284_11 Ribbon-helix-helix protein, copG family - - - 0.00000000000000000000000000000000000000000000000001124 187.0
SX1_k127_1499284_12 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.000000000000000000000000000000000000000000000009058 178.0
SX1_k127_1499284_13 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 GO:0000041,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006826,GO:0008150,GO:0008152,GO:0008823,GO:0015677,GO:0015682,GO:0016020,GO:0016021,GO:0016491,GO:0016722,GO:0016723,GO:0030001,GO:0031224,GO:0031226,GO:0033216,GO:0034220,GO:0034755,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0052851,GO:0055085,GO:0055114,GO:0071944,GO:0072512,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098706,GO:0098711,GO:0098739,GO:0099587 1.5.1.40 0.00000000000000000000000000000000000000001524 162.0
SX1_k127_1499284_14 ERCC4 domain protein K10848 - - 0.00000000000723 76.0
SX1_k127_1499284_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 608.0
SX1_k127_1499284_3 Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 608.0
SX1_k127_1499284_4 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 593.0
SX1_k127_1499284_5 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 440.0
SX1_k127_1499284_6 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 385.0
SX1_k127_1499284_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 312.0
SX1_k127_1499284_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
SX1_k127_1499284_9 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002149 249.0
SX1_k127_155431_0 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 496.0
SX1_k127_155431_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 454.0
SX1_k127_155431_10 Pas domain s-box - - - 0.000000000000000000000000000000000000000000000000000000000002651 228.0
SX1_k127_155431_11 Belongs to the FPP GGPP synthase family K00805 - 2.5.1.30 0.000000000000000000000000000000000000000000000000000000000004412 220.0
SX1_k127_155431_12 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000005325 195.0
SX1_k127_155431_13 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000002031 194.0
SX1_k127_155431_14 cell wall organization - - - 0.0000000000000000000000000000000000000000000004743 182.0
SX1_k127_155431_15 MgtC family - - - 0.000000000000000000000000000000000000000000004733 179.0
SX1_k127_155431_16 PFAM MazG nucleotide pyrophosphohydrolase domain - - - 0.0000000000000000000000000002138 120.0
SX1_k127_155431_17 Bacterial regulatory protein, Fis family K07714 - - 0.00000000000000001097 97.0
SX1_k127_155431_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000103 78.0
SX1_k127_155431_19 peptidase U32 - - - 0.000000000001072 79.0
SX1_k127_155431_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one- carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 443.0
SX1_k127_155431_20 Belongs to the UPF0235 family K09131 - - 0.000000000008741 69.0
SX1_k127_155431_21 YHS domain - - - 0.00000000003138 72.0
SX1_k127_155431_22 TOPRIM - - - 0.0000000004461 71.0
SX1_k127_155431_23 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0003712 53.0
SX1_k127_155431_3 phosphoesterase RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 423.0
SX1_k127_155431_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 410.0
SX1_k127_155431_5 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 334.0
SX1_k127_155431_6 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000005861 271.0
SX1_k127_155431_7 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003419 256.0
SX1_k127_155431_8 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000001285 243.0
SX1_k127_155431_9 Cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000001903 237.0
SX1_k127_1591815_0 formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 7.044e-225 709.0
SX1_k127_1591815_1 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 556.0
SX1_k127_1591815_10 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000001928 98.0
SX1_k127_1591815_11 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11260,K14107 - - 0.00000000000007856 80.0
SX1_k127_1591815_12 Predicted membrane protein (DUF2101) - - - 0.000002422 58.0
SX1_k127_1591815_14 membrane - - - 0.00005197 56.0
SX1_k127_1591815_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 373.0
SX1_k127_1591815_3 formylmethanofuran dehydrogenase, subunit C K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000008563 268.0
SX1_k127_1591815_4 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000000000000000000001991 214.0
SX1_k127_1591815_5 GAF domain - - - 0.00000000000000000000000000000000000000000000000000001636 211.0
SX1_k127_1591815_6 4Fe-4S dicluster domain K00205 - - 0.000000000000000000000000000000000000000000000000003444 192.0
SX1_k127_1591815_7 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000006109 147.0
SX1_k127_1591815_8 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.000000000000000000000000000000771 126.0
SX1_k127_1591815_9 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000002482 108.0
SX1_k127_1623332_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 520.0
SX1_k127_1623332_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 497.0
SX1_k127_1623332_10 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 314.0
SX1_k127_1623332_11 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 297.0
SX1_k127_1623332_12 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 289.0
SX1_k127_1623332_13 50S ribosomal protein L4 K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 286.0
SX1_k127_1623332_14 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001848 292.0
SX1_k127_1623332_15 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005329 253.0
SX1_k127_1623332_16 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000007429 256.0
SX1_k127_1623332_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000006081 243.0
SX1_k127_1623332_18 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000001142 248.0
SX1_k127_1623332_19 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000007107 224.0
SX1_k127_1623332_2 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 494.0
SX1_k127_1623332_20 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003444 216.0
SX1_k127_1623332_21 Belongs to the archaeal adenylate kinase family K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000003759 216.0
SX1_k127_1623332_22 Has ATPase and non-specific DNA-binding activities K07456 - - 0.000000000000000000000000000000000000000000000000000000000001159 224.0
SX1_k127_1623332_23 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000119 211.0
SX1_k127_1623332_24 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000003585 221.0
SX1_k127_1623332_25 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000007486 199.0
SX1_k127_1623332_26 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000009177 201.0
SX1_k127_1623332_27 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000001538 198.0
SX1_k127_1623332_28 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000003037 179.0
SX1_k127_1623332_29 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000543 177.0
SX1_k127_1623332_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 489.0
SX1_k127_1623332_30 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000219 175.0
SX1_k127_1623332_31 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000001052 169.0
SX1_k127_1623332_32 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000001153 169.0
SX1_k127_1623332_33 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000003139 166.0
SX1_k127_1623332_34 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000005194 166.0
SX1_k127_1623332_35 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000001477 164.0
SX1_k127_1623332_36 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000001591 162.0
SX1_k127_1623332_37 TIGRFAM ribosomal protein L30P K02907 - - 0.0000000000000000000000000000000000000000001632 163.0
SX1_k127_1623332_38 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000007686 155.0
SX1_k127_1623332_39 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000007011 154.0
SX1_k127_1623332_4 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 401.0
SX1_k127_1623332_40 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001354 149.0
SX1_k127_1623332_41 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000007806 152.0
SX1_k127_1623332_42 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.00000000000000000000000000000000000001533 166.0
SX1_k127_1623332_43 binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000000002221 151.0
SX1_k127_1623332_44 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000001351 150.0
SX1_k127_1623332_45 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001515 131.0
SX1_k127_1623332_46 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000003881 128.0
SX1_k127_1623332_47 binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002084 124.0
SX1_k127_1623332_48 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000204 104.0
SX1_k127_1623332_49 Integral membrane protein DUF106 - - - 0.00000000000000000000003351 109.0
SX1_k127_1623332_5 PFAM AAA ATPase central domain protein K07392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 395.0
SX1_k127_1623332_50 Belongs to the eukaryotic ribosomal protein eL14 family K02875 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000008889 100.0
SX1_k127_1623332_51 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000001913 99.0
SX1_k127_1623332_52 Belongs to the eukaryotic ribosomal protein eL34 family K02915 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001403 97.0
SX1_k127_1623332_53 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000000000001524 84.0
SX1_k127_1623332_54 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000002646 80.0
SX1_k127_1623332_55 - - - - 0.0000000000000004969 84.0
SX1_k127_1623332_56 PFAM Ribosomal protein K02912 - - 0.000000000000002624 82.0
SX1_k127_1623332_57 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014,K03055 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000004356 79.0
SX1_k127_1623332_58 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.0000000000002116 70.0
SX1_k127_1623332_59 Has ATPase and non-specific DNA-binding activities K07456 - - 0.0000000006055 70.0
SX1_k127_1623332_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 370.0
SX1_k127_1623332_60 Belongs to the eukaryotic ribosomal protein eL13 family K02873 - - 0.00002489 53.0
SX1_k127_1623332_61 Stage II sporulation protein M - - - 0.00002755 55.0
SX1_k127_1623332_7 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 366.0
SX1_k127_1623332_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 321.0
SX1_k127_1623332_9 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 305.0
SX1_k127_1634234_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 375.0
SX1_k127_1634234_1 GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000001679 239.0
SX1_k127_1634234_10 Zn-ribbon containing protein K07163 - - 0.00000000000001639 78.0
SX1_k127_1634234_11 Carboxypeptidase regulatory-like domain - - - 0.0000000000004189 82.0
SX1_k127_1634234_2 serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000004473 237.0
SX1_k127_1634234_3 MviN-like protein - - - 0.00000000000000000000000000000000000000000000000000008414 202.0
SX1_k127_1634234_4 SMART KH domain protein K06961 - - 0.000000000000000000000000000000000000000000000000889 180.0
SX1_k127_1634234_5 mRNA decay K07562 - - 0.0000000000000000000000000000000000006207 151.0
SX1_k127_1634234_6 PFAM Peptidase - - - 0.000000000000000000000000000000001404 134.0
SX1_k127_1634234_7 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000002482 129.0
SX1_k127_1634234_8 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000002632 116.0
SX1_k127_1634234_9 protein conserved in archaea K09743 - - 0.00000000000000001084 89.0
SX1_k127_1638930_1 cellulase activity - - - 0.0000003701 65.0
SX1_k127_1638930_2 SMART AAA ATPase K06915 - - 0.0006815 55.0
SX1_k127_16887_0 ATPases associated with a variety of cellular activities K01990,K11050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001701 246.0
SX1_k127_16887_1 MlaD protein K02067 - - 0.000000000000001395 86.0
SX1_k127_1730941_0 PFAM Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 526.0
SX1_k127_1730941_1 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000003981 196.0
SX1_k127_1730941_2 PFAM AsnC family - - - 0.000000000000000000000000000000000000000000000000000232 189.0
SX1_k127_1730941_3 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.00000000000000000000000000000000002374 151.0
SX1_k127_1730941_4 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.0000000000000000000000000000000158 131.0
SX1_k127_1730941_5 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000000001604 125.0
SX1_k127_1730941_6 Catalyzes the synthesis of activated sulfate K00860,K07028 - 2.7.1.25 0.0000000000000000000000000009445 119.0
SX1_k127_1730941_7 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.0000000000000000000003969 113.0
SX1_k127_1730941_8 ORF D-335-like protein - - - 0.0000004932 51.0
SX1_k127_18043_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 5.266e-286 903.0
SX1_k127_18043_1 Acetolactate synthase, large subunit K01652 - 2.2.1.6 1.046e-218 691.0
SX1_k127_18043_10 His Kinase A (phospho-acceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002364 247.0
SX1_k127_18043_11 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000007031 235.0
SX1_k127_18043_12 MobA-like NTP transferase domain K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000008107 228.0
SX1_k127_18043_13 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000003287 216.0
SX1_k127_18043_14 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000142 212.0
SX1_k127_18043_15 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000001122 181.0
SX1_k127_18043_16 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000001372 179.0
SX1_k127_18043_17 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000001029 164.0
SX1_k127_18043_18 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000008737 156.0
SX1_k127_18043_19 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000002059 165.0
SX1_k127_18043_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.171e-208 658.0
SX1_k127_18043_20 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000001264 143.0
SX1_k127_18043_21 cheY-homologous receiver domain K07668 - - 0.0000000000000000000000000004226 118.0
SX1_k127_18043_22 Type IV leader peptidase family K07991 - 3.4.23.52 0.00000000000000000000000001231 123.0
SX1_k127_18043_23 cheY-homologous receiver domain K07668 - - 0.00000000000000000000000002396 112.0
SX1_k127_18043_24 PFAM response regulator receiver - - - 0.000000000000000000000001372 111.0
SX1_k127_18043_25 cheY-homologous receiver domain K07668 - - 0.00000000000000000000003835 107.0
SX1_k127_18043_26 archaeal coiled-coil protein - - - 0.00000000000000000000134 105.0
SX1_k127_18043_27 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000008742 76.0
SX1_k127_18043_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.82e-207 656.0
SX1_k127_18043_4 PFAM Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 460.0
SX1_k127_18043_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 421.0
SX1_k127_18043_6 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 304.0
SX1_k127_18043_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 286.0
SX1_k127_18043_8 Diphthamide K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001136 286.0
SX1_k127_18043_9 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001329 242.0
SX1_k127_1879466_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 561.0
SX1_k127_1879466_1 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 408.0
SX1_k127_1879466_10 HWE histidine kinase - - - 0.00000000000000000000000000000000001984 156.0
SX1_k127_1879466_11 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000000005433 98.0
SX1_k127_1879466_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000001792 78.0
SX1_k127_1879466_13 - - - - 0.00000000000004292 75.0
SX1_k127_1879466_14 Protein of unknown function (DUF447) K09154 - - 0.000000004758 67.0
SX1_k127_1879466_15 Nucleotidyl transferase K03241 GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005851,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0010646,GO:0010648,GO:0019222,GO:0019538,GO:0019899,GO:0031323,GO:0031326,GO:0032045,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032991,GO:0034248,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0051020,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903574,GO:1903832,GO:2000112 - 0.000001727 54.0
SX1_k127_1879466_2 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 GO:0003674,GO:0003824,GO:0016874,GO:0016879,GO:0016881,GO:0052618 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009136 282.0
SX1_k127_1879466_3 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001746 281.0
SX1_k127_1879466_4 C D box methylation guide ribonucleoprotein complex aNOP56 subunit K14564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003179 279.0
SX1_k127_1879466_5 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.00000000000000000000000000000000000000000000000000000000000002292 228.0
SX1_k127_1879466_6 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000000000000000000765 239.0
SX1_k127_1879466_7 ATP-grasp domain K06914 - 6.3.4.24 0.0000000000000000000000000000000000000000000000000000000000013 221.0
SX1_k127_1879466_8 H4MPT-linked C1 transfer pathway protein K07072 - 2.5.1.131 0.0000000000000000000000000000000000000000000000000000000001179 216.0
SX1_k127_1879466_9 ATP dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000007228 198.0
SX1_k127_188132_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 501.0
SX1_k127_188132_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 397.0
SX1_k127_188132_10 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000003349 153.0
SX1_k127_188132_11 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071236,GO:0140096 - 0.000000000000000000000000003956 119.0
SX1_k127_188132_12 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.000000000000000000000000005548 113.0
SX1_k127_188132_13 NifU-like domain - - - 0.00000000000000000000000009562 108.0
SX1_k127_188132_14 binds to the 23S rRNA K02922 - - 0.0000000000000000000000001856 106.0
SX1_k127_188132_15 Belongs to the UPF0147 family K09721 - - 0.0000000000000000000002508 98.0
SX1_k127_188132_16 Signal transduction histidine kinase K02487,K06596 - - 0.0000000000000000000005407 100.0
SX1_k127_188132_17 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.000000000004497 70.0
SX1_k127_188132_18 PFAM Glycosyl transferase family 4 K01001 - 2.7.8.15 0.000002056 53.0
SX1_k127_188132_2 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 362.0
SX1_k127_188132_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 354.0
SX1_k127_188132_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 347.0
SX1_k127_188132_5 Trypsin K08070,K08372 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 330.0
SX1_k127_188132_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001891 262.0
SX1_k127_188132_7 PFAM amino acid-binding ACT domain protein K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001057 248.0
SX1_k127_188132_8 Nicotinamide-nucleotide adenylyltransferase K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000000004322 234.0
SX1_k127_188132_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000004861 212.0
SX1_k127_1929722_0 Thioredoxin - - - 0.00000000000000000000000000000000000000000001578 168.0
SX1_k127_1929722_1 Pfam:KaiC - - - 0.0000000000000000000000000000000000000005726 158.0
SX1_k127_1929722_2 - - - - 0.000000000001435 77.0
SX1_k127_1988435_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 599.0
SX1_k127_1988435_1 TIGRFAM dihydropteroate synthase-related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 314.0
SX1_k127_1988435_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000002863 133.0
SX1_k127_1988435_3 Belongs to the ompA family K20276 - - 0.00000000000000000000000000006795 134.0
SX1_k127_1988435_4 Required for chromosome condensation and partitioning - - - 0.00002017 58.0
SX1_k127_1988435_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0001303 55.0
SX1_k127_1991645_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.2.7.4 7.187e-279 877.0
SX1_k127_1991645_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.976e-201 650.0
SX1_k127_1991645_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 382.0
SX1_k127_1991645_11 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 349.0
SX1_k127_1991645_12 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 335.0
SX1_k127_1991645_13 Proton-conducting membrane transporter K22169 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 337.0
SX1_k127_1991645_14 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 324.0
SX1_k127_1991645_15 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 314.0
SX1_k127_1991645_16 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 302.0
SX1_k127_1991645_17 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 296.0
SX1_k127_1991645_18 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 291.0
SX1_k127_1991645_19 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K22174 - 1.1.98.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 304.0
SX1_k127_1991645_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl- CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00192,K00193 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 511.0
SX1_k127_1991645_20 Phosphopantothenate/pantothenate synthetase K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 285.0
SX1_k127_1991645_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000006852 274.0
SX1_k127_1991645_22 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001311 269.0
SX1_k127_1991645_23 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000001298 251.0
SX1_k127_1991645_24 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003137 228.0
SX1_k127_1991645_25 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K21816 - 1.8.98.3 0.00000000000000000000000000000000000000000000000000000000003234 219.0
SX1_k127_1991645_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000001513 190.0
SX1_k127_1991645_27 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.000000000000000000000000000000000000000000000003594 181.0
SX1_k127_1991645_28 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000001935 179.0
SX1_k127_1991645_29 GHMP kinases N terminal domain K06982 - 2.7.1.169 0.0000000000000000000000000000000000000000000007995 179.0
SX1_k127_1991645_3 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 481.0
SX1_k127_1991645_30 Putative Fe-S cluster K11260 - - 0.0000000000000000000000000000000000000003339 155.0
SX1_k127_1991645_31 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000005248 153.0
SX1_k127_1991645_32 Adenylate cyclase K05873 - 4.6.1.1 0.000000000000000000000000000000002378 136.0
SX1_k127_1991645_33 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.0000000000000000000000000002907 124.0
SX1_k127_1991645_34 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.00000000000000000000006372 102.0
SX1_k127_1991645_35 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000002764 97.0
SX1_k127_1991645_36 Belongs to the UPF0248 family K09715 - - 0.0000000000000004256 80.0
SX1_k127_1991645_37 In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha- aminoadipate (AAA) pathway K06154 - - 0.000000000000001856 82.0
SX1_k127_1991645_38 Sugar-specific transcriptional regulator TrmB - - - 0.000000000004682 76.0
SX1_k127_1991645_39 - K00533,K03616 - 1.12.7.2 0.000000003487 59.0
SX1_k127_1991645_4 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 473.0
SX1_k127_1991645_40 NADH ubiquinone oxidoreductase subunit 6 (chain J) K00339 - 1.6.5.3 0.00000002341 59.0
SX1_k127_1991645_41 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0004679 46.0
SX1_k127_1991645_5 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 467.0
SX1_k127_1991645_6 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2) K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 459.0
SX1_k127_1991645_7 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 452.0
SX1_k127_1991645_8 small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 428.0
SX1_k127_1991645_9 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 374.0
SX1_k127_2001105_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 2.962e-241 762.0
SX1_k127_2001105_1 Belongs to the RtcB family K14415 - 6.5.1.3 2.441e-210 665.0
SX1_k127_2001105_10 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000273 265.0
SX1_k127_2001105_11 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000001424 241.0
SX1_k127_2001105_12 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000004061 138.0
SX1_k127_2001105_13 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000000000004107 133.0
SX1_k127_2001105_14 PFAM Peptidase S24 S26A S26B, conserved region K13280 - 3.4.21.89 0.00000000000000001625 93.0
SX1_k127_2001105_15 SMART Cold shock protein K03704 - - 0.0000000000000002456 79.0
SX1_k127_2001105_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 560.0
SX1_k127_2001105_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 543.0
SX1_k127_2001105_4 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 492.0
SX1_k127_2001105_5 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 461.0
SX1_k127_2001105_6 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 397.0
SX1_k127_2001105_7 PFAM peptidase U62 modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 366.0
SX1_k127_2001105_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 325.0
SX1_k127_2001105_9 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 325.0
SX1_k127_2002014_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 352.0
SX1_k127_2002014_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007783 278.0
SX1_k127_2002014_2 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000001613 267.0
SX1_k127_2002014_3 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000001903 168.0
SX1_k127_2002014_4 PFAM Cysteine-rich small domain K07162 - - 0.00000000000000000000001451 105.0
SX1_k127_2037326_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00005329 50.0
SX1_k127_2132714_0 Thi4 family K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 571.0
SX1_k127_2132714_1 Na+/Pi-cotransporter K14683 - - 0.000000003351 60.0
SX1_k127_2149065_0 - - - - 0.0000000000000000000000000000000000000000000000000000002704 196.0
SX1_k127_2149065_1 Methyltransferase domain K06987 - - 0.0000000000000000000000000000000009294 139.0
SX1_k127_2149065_2 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000002009 104.0
SX1_k127_2149065_3 membrane protein (DUF2178) - - - 0.000000000000000000006651 96.0
SX1_k127_2211326_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 507.0
SX1_k127_2211326_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 466.0
SX1_k127_2211326_2 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 378.0
SX1_k127_2211326_3 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 265.0
SX1_k127_2211326_4 Belongs to the UPF0179 family K09730 - - 0.0000000000000000000000001401 111.0
SX1_k127_2211326_5 Membrane protein of unknown function DUF63 - - - 0.00000000000000000000001019 110.0
SX1_k127_2371286_0 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 298.0
SX1_k127_2371286_1 Putative O-antigen polymerase - - - 0.0000000000000000000000003669 120.0
SX1_k127_2371286_2 Archaeal transcriptional regulator TrmB - - - 0.00000000000000002548 91.0
SX1_k127_2371322_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000071 129.0
SX1_k127_2391878_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.905e-260 827.0
SX1_k127_2391878_1 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893 423.0
SX1_k127_2391878_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 304.0
SX1_k127_2391878_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005729 258.0
SX1_k127_2391878_4 flavin reductase - - - 0.000000000000000000000000000000000000000005084 161.0
SX1_k127_2391878_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000007394 63.0
SX1_k127_2403228_0 HELICc2 K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000001678 194.0
SX1_k127_2403228_1 Domain of unknown function - - - 0.000000000005161 80.0
SX1_k127_2424772_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.27e-215 679.0
SX1_k127_2424772_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 603.0
SX1_k127_2424772_10 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000025 184.0
SX1_k127_2424772_11 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000001419 177.0
SX1_k127_2424772_12 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000002746 142.0
SX1_k127_2424772_13 - - - - 0.000000000000000000000004324 106.0
SX1_k127_2424772_14 Peptidase M50 - - - 0.0000000000000000000001768 112.0
SX1_k127_2424772_15 CBS domain - - - 0.000000000000000000003244 99.0
SX1_k127_2424772_16 Starch synthase catalytic domain K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.0000000000004148 82.0
SX1_k127_2424772_17 Protein of unknown function DUF47 K07220 - - 0.00000002053 63.0
SX1_k127_2424772_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 570.0
SX1_k127_2424772_3 Quinolinate phosphoribosyl transferase, N-terminal domain K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 457.0
SX1_k127_2424772_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 448.0
SX1_k127_2424772_5 PFAM glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 425.0
SX1_k127_2424772_6 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 395.0
SX1_k127_2424772_7 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 366.0
SX1_k127_2424772_8 PFAM Sugar isomerase (SIS) K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 321.0
SX1_k127_2424772_9 Peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000002201 198.0
SX1_k127_2455507_0 Molybdenum cofactor synthesis domain protein K03750,K07219 - 2.10.1.1 5.449e-214 683.0
SX1_k127_2455507_1 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 524.0
SX1_k127_2455507_2 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 466.0
SX1_k127_2455507_3 PFAM Formylmethanofuran tetrahydromethanopterin formyltransferase Ftr K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 391.0
SX1_k127_2455507_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 359.0
SX1_k127_2455507_5 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006814 263.0
SX1_k127_2455507_6 - - - - 0.0000000000000000000000000000000000000000000000000000000008851 219.0
SX1_k127_2455507_7 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000009014 149.0
SX1_k127_2455507_8 Belongs to the carbohydrate kinase PfkB family K21057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704 2.7.1.213 0.000000000000000000000000000148 126.0
SX1_k127_2455507_9 - - - - 0.00000000001454 68.0
SX1_k127_2473873_0 P-type ATPase K01537 - 3.6.3.8 6.32e-236 765.0
SX1_k127_2473873_1 AIR synthase related protein domain protein K07388 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 460.0
SX1_k127_2473873_2 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 437.0
SX1_k127_2473873_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 358.0
SX1_k127_2473873_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000004056 216.0
SX1_k127_2473873_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000001513 212.0
SX1_k127_2473873_6 Methionine biosynthesis protein MetW - - - 0.0000000000001737 79.0
SX1_k127_2473873_7 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000009046 70.0
SX1_k127_2473873_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00002134 54.0
SX1_k127_2473873_9 - - - - 0.0003248 47.0
SX1_k127_2484357_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000002669 235.0
SX1_k127_2484357_1 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000004082 136.0
SX1_k127_2484357_2 Thioredoxin-like - - - 0.000000000000000000000000004033 121.0
SX1_k127_2493444_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.108e-298 938.0
SX1_k127_2493444_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.076e-284 888.0
SX1_k127_2493444_10 SpoU rRNA Methylase family - - - 0.00000000000000000000000000000000000000000000000481 189.0
SX1_k127_2493444_11 Involved in cell shape control K22222 - - 0.000000000000000000000000000000000000009178 159.0
SX1_k127_2493444_12 Involved in cell shape control K22222 - - 0.000000000000000000000000001574 124.0
SX1_k127_2493444_13 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000001158 106.0
SX1_k127_2493444_14 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000000002133 94.0
SX1_k127_2493444_15 Pfam:DUF70 - - - 0.00000000000002173 85.0
SX1_k127_2493444_16 PFAM Tetratricopeptide repeat - - - 0.0000001893 61.0
SX1_k127_2493444_2 Cell division protein 48 (CDC48) N-terminal domain K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008881 447.0
SX1_k127_2493444_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 435.0
SX1_k127_2493444_4 Involved in cell shape control K22222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 386.0
SX1_k127_2493444_5 DUF1512 domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001617 279.0
SX1_k127_2493444_6 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000007643 274.0
SX1_k127_2493444_7 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000002242 215.0
SX1_k127_2493444_8 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000000000007766 216.0
SX1_k127_2493444_9 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000003655 197.0
SX1_k127_2503211_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 509.0
SX1_k127_2503211_1 isocitrate dehydrogenase (NAD+) activity K00030 GO:0000166,GO:0003674,GO:0003824,GO:0004448,GO:0004449,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006102,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009507,GO:0009536,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.1.1.41 0.000002897 49.0
SX1_k127_2503323_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.576e-208 662.0
SX1_k127_2503323_1 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000263 202.0
SX1_k127_2503323_2 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000007054 151.0
SX1_k127_2539827_0 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 541.0
SX1_k127_2539827_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 526.0
SX1_k127_2539827_10 PFAM ABC transporter related K01990,K16907 - - 0.000000000000000000000000000000000000000000000001091 183.0
SX1_k127_2539827_11 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000004858 166.0
SX1_k127_2539827_12 ABC-type transport system involved in cytochrome c biogenesis permease component K02194 - - 0.000000000000000000000000000000000000000001798 164.0
SX1_k127_2539827_13 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000005066 148.0
SX1_k127_2539827_14 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000000000003116 138.0
SX1_k127_2539827_15 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.0000000000000000000000000000000006363 137.0
SX1_k127_2539827_16 CBS domain - - - 0.000000000000000000000000000000659 125.0
SX1_k127_2539827_17 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000002594 108.0
SX1_k127_2539827_18 4Fe-4S binding domain - - - 0.00000000000000000006486 98.0
SX1_k127_2539827_19 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000001952 100.0
SX1_k127_2539827_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 501.0
SX1_k127_2539827_20 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.00000000000000362 76.0
SX1_k127_2539827_21 Protein of unknown function DUF131 - - - 0.00000000004256 66.0
SX1_k127_2539827_22 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH - - - 0.00000002186 62.0
SX1_k127_2539827_3 Phenylalanyl-tRNA synthetase beta K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 505.0
SX1_k127_2539827_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 476.0
SX1_k127_2539827_5 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 379.0
SX1_k127_2539827_6 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 350.0
SX1_k127_2539827_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000003147 249.0
SX1_k127_2539827_8 PFAM zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000001928 253.0
SX1_k127_2539827_9 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000003404 228.0
SX1_k127_2556238_0 SMART KH domain protein K07041 - - 1.029e-249 785.0
SX1_k127_2556238_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.796e-194 613.0
SX1_k127_2556238_10 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001313 220.0
SX1_k127_2556238_11 Domain of unknown function (DUF1724) - - - 0.000000000000000000000000000000000000000000000000000000000003164 217.0
SX1_k127_2556238_12 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000001398 209.0
SX1_k127_2556238_13 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000008802 191.0
SX1_k127_2556238_14 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000002188 180.0
SX1_k127_2556238_15 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000000000000008176 168.0
SX1_k127_2556238_16 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000001033 170.0
SX1_k127_2556238_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K19694 - - 0.0000000000000000000000000000000000001035 151.0
SX1_k127_2556238_18 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000004058 108.0
SX1_k127_2556238_19 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000000000000001964 87.0
SX1_k127_2556238_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 434.0
SX1_k127_2556238_20 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000007225 49.0
SX1_k127_2556238_21 - - - - 0.0001924 46.0
SX1_k127_2556238_3 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 357.0
SX1_k127_2556238_4 TatD related DNase K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006454 275.0
SX1_k127_2556238_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000184 256.0
SX1_k127_2556238_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000231 242.0
SX1_k127_2556238_7 Nucleotidyltransferase domain K07073 - - 0.0000000000000000000000000000000000000000000000000000000000000001278 228.0
SX1_k127_2556238_8 PFAM UbiA prenyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002999 221.0
SX1_k127_2556238_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000399 214.0
SX1_k127_2610367_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.22e-249 786.0
SX1_k127_2610367_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.035e-203 649.0
SX1_k127_2610367_10 PFAM Cation K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007972 292.0
SX1_k127_2610367_11 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000005379 239.0
SX1_k127_2610367_12 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000005554 225.0
SX1_k127_2610367_13 Tripartite tricarboxylate transporter TctA family K08971 - - 0.000000000000000000000000000000000000000000000000001656 193.0
SX1_k127_2610367_14 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000122 171.0
SX1_k127_2610367_15 Cytidylyltransferase K19712 - 2.7.7.62 0.0000000000000000000000000000000000000000001295 168.0
SX1_k127_2610367_16 Protein of unknown function (DUF434) - - - 0.0000000000000000000000000000000000000003057 157.0
SX1_k127_2610367_17 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000378 156.0
SX1_k127_2610367_18 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000003575 151.0
SX1_k127_2610367_19 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000001874 136.0
SX1_k127_2610367_2 Ferrous iron transport protein B K04759 - - 3.975e-199 639.0
SX1_k127_2610367_20 Helix-turn-helix diphteria tox regulatory element - - - 0.00000000000000000000000000002556 121.0
SX1_k127_2610367_21 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000002137 121.0
SX1_k127_2610367_22 Fcf1 K07158 - - 0.00000000000000000000000006683 118.0
SX1_k127_2610367_23 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.000000000000000000000001142 104.0
SX1_k127_2610367_24 signal transduction protein with CBS domains - - - 0.000000000000000000000001261 108.0
SX1_k127_2610367_25 - - - - 0.0000000000000000000003352 103.0
SX1_k127_2610367_26 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000000184 94.0
SX1_k127_2610367_27 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000009921 78.0
SX1_k127_2610367_28 PFAM Trm112p-like protein - - - 0.00000000001793 67.0
SX1_k127_2610367_29 Nucleic acid binding - - - 0.0000000004956 70.0
SX1_k127_2610367_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 574.0
SX1_k127_2610367_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 563.0
SX1_k127_2610367_5 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 532.0
SX1_k127_2610367_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 417.0
SX1_k127_2610367_7 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 371.0
SX1_k127_2610367_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 347.0
SX1_k127_2610367_9 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 292.0
SX1_k127_2738388_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 546.0
SX1_k127_2738388_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005539 278.0
SX1_k127_2738388_2 PFAM Glycosyl transferase family 4 K01001 - 2.7.8.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001482 259.0
SX1_k127_2738388_3 Glycosyltransferase 28 domain - - - 0.000000000000000000000000000000000000000001174 164.0
SX1_k127_2738388_4 PFAM Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000008703 135.0
SX1_k127_2738388_5 glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000002936 134.0
SX1_k127_2738388_6 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000003285 78.0
SX1_k127_2776064_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000008232 228.0
SX1_k127_2776064_1 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.00000000000000000000000000000033 132.0
SX1_k127_2776064_2 - - - - 0.0000000001722 64.0
SX1_k127_2801146_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 623.0
SX1_k127_2801146_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 546.0
SX1_k127_2801146_10 PFAM TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000002844 235.0
SX1_k127_2801146_11 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000002673 154.0
SX1_k127_2801146_12 peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.0000000000000000000000000009088 114.0
SX1_k127_2801146_13 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000006694 104.0
SX1_k127_2801146_14 Lrp/AsnC ligand binding domain - - - 0.00000000000000000006486 91.0
SX1_k127_2801146_15 - - - - 0.000000297 59.0
SX1_k127_2801146_2 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 507.0
SX1_k127_2801146_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 501.0
SX1_k127_2801146_4 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 489.0
SX1_k127_2801146_5 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 389.0
SX1_k127_2801146_6 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 346.0
SX1_k127_2801146_7 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 303.0
SX1_k127_2801146_8 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 287.0
SX1_k127_2801146_9 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000009676 246.0
SX1_k127_28024_0 type II secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 578.0
SX1_k127_28024_1 KaiC - - - 0.0000000000000000000000000000000000000000000000000001634 194.0
SX1_k127_28024_2 Protein of unknown function (DUF2507) K07013 - - 0.00000000000000001738 92.0
SX1_k127_28024_3 Endonuclease Exonuclease Phosphatase - - - 0.000000000001137 78.0
SX1_k127_28024_4 Protein conserved in bacteria K20276 - - 0.0000001075 64.0
SX1_k127_2812491_0 Histidine kinase - - - 0.00000000000000002734 91.0
SX1_k127_2812491_1 Roadblock/LC7 domain K07131 - - 0.000005297 53.0
SX1_k127_2812491_2 PFAM Class III signal peptide - - - 0.0006373 44.0
SX1_k127_2821471_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000003301 187.0
SX1_k127_2821471_1 - - - - 0.000000009491 58.0
SX1_k127_285238_0 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 363.0
SX1_k127_285238_1 zinc-ribbon domain - - - 0.00000000000000000000002698 112.0
SX1_k127_285238_2 - - - - 0.000000000008609 72.0
SX1_k127_285238_3 serine threonine protein kinase - - - 0.0000000001364 74.0
SX1_k127_285238_4 Protein of unknown function DUF47 K07220 - - 0.000005261 52.0
SX1_k127_285238_5 - - - - 0.0009245 52.0
SX1_k127_2918047_0 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 467.0
SX1_k127_2918047_1 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 306.0
SX1_k127_2918047_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000001265 235.0
SX1_k127_2918047_3 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000007667 206.0
SX1_k127_2918047_5 Belongs to the eukaryotic ribosomal protein eL33 family K02917 - - 0.0004847 50.0
SX1_k127_3018995_0 PFAM ABC transporter K02003,K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 288.0
SX1_k127_3018995_1 MacB-like periplasmic core domain K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005871 260.0
SX1_k127_3018995_2 MacB-like periplasmic core domain K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000004267 249.0
SX1_k127_3018995_3 extracellular matrix structural constituent - - - 0.00000000000000002774 87.0
SX1_k127_3019692_0 - - - - 0.0005664 51.0
SX1_k127_3026379_0 Cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 433.0
SX1_k127_3026379_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 335.0
SX1_k127_3026379_10 PFAM 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0001499 45.0
SX1_k127_3026379_11 MYM-type Zinc finger with FCS sequence motif - - - 0.0009222 42.0
SX1_k127_3026379_2 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000006914 209.0
SX1_k127_3026379_3 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000005541 198.0
SX1_k127_3026379_4 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000106 136.0
SX1_k127_3026379_5 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000006384 121.0
SX1_k127_3026379_6 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.0000000000000000000006426 97.0
SX1_k127_3026379_7 - - - - 0.00000000000002189 78.0
SX1_k127_3026379_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000001451 72.0
SX1_k127_3026379_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000005778 50.0
SX1_k127_3030141_0 Radical SAM K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 433.0
SX1_k127_3030141_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 293.0
SX1_k127_3030141_10 - - - - 0.000005505 56.0
SX1_k127_3030141_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000958 265.0
SX1_k127_3030141_3 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000001307 248.0
SX1_k127_3030141_4 ABC-type tungstate transport system, periplasmic component K05773 - - 0.00000000000000000000000000000000000000000000000000000000008514 213.0
SX1_k127_3030141_5 PFAM Sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000000001816 199.0
SX1_k127_3030141_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.00000000000000000000000000000000000000001134 162.0
SX1_k127_3030141_7 Oligosaccharyl transferase, STT3 subunit K07151 - 2.4.99.18 0.000000000000000000000000000000000001568 160.0
SX1_k127_3030141_8 transcriptional regulatory protein K09714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000001748 81.0
SX1_k127_3030141_9 COG1522 Transcriptional regulators - - - 0.00000000000001692 86.0
SX1_k127_3033754_0 Large family of predicted nucleotide-binding domains K06865 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 583.0
SX1_k127_3033754_1 Permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000005935 208.0
SX1_k127_3033754_2 Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position K01271 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.13.9 0.00000000000000000000000000000000000000000000000000000001024 210.0
SX1_k127_3033754_3 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000884 160.0
SX1_k127_3033754_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 - 2.7.7.3 0.0000000000000000000000000000000003091 137.0
SX1_k127_3033754_5 regulatory protein, arsR K03892 - - 0.0000000000000000000000000181 111.0
SX1_k127_3033754_6 redox-active disulfide protein 2 - - - 0.0000000000000000000001426 98.0
SX1_k127_3033754_7 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0001425 55.0
SX1_k127_305968_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 432.0
SX1_k127_305968_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 392.0
SX1_k127_305968_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 297.0
SX1_k127_305968_3 HTH-type transcriptional regulatory protein K07728 - - 0.000000000000000000000000000000000000000000000000000000003183 210.0
SX1_k127_305968_4 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000005284 149.0
SX1_k127_305968_5 Protein of unknown function (DUF429) K09147 - - 0.00000000000000000000000000006553 123.0
SX1_k127_305968_6 cell wall binding repeat 2-containing protein - - - 0.000000000000000000002119 107.0
SX1_k127_305968_7 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000002464 98.0
SX1_k127_305968_8 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.0000000000000000013 91.0
SX1_k127_305968_9 protein conserved in archaea - - - 0.00000001941 61.0
SX1_k127_3203814_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 448.0
SX1_k127_3203814_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 381.0
SX1_k127_3203814_2 - - - - 0.00000000000000002398 86.0
SX1_k127_3203814_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00007828 46.0
SX1_k127_3227647_0 Pyruvate kinase K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 411.0
SX1_k127_3227647_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.000000000000000000000000000000000000003874 148.0
SX1_k127_3227647_2 Rubrerythrin K19824 - - 0.00000000000000000000000000000000009561 142.0
SX1_k127_3251975_0 histone acetyltransferase K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 565.0
SX1_k127_3251975_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 464.0
SX1_k127_3251975_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000002 203.0
SX1_k127_3251975_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000001257 148.0
SX1_k127_3251975_4 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity K00549 - 2.1.1.14 0.000000000000000006256 87.0
SX1_k127_3251975_5 Mo-molybdopterin cofactor metabolic process K03750,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.0000000000000006751 89.0
SX1_k127_3251975_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000001974 58.0
SX1_k127_3251975_7 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000162 57.0
SX1_k127_3251975_8 Cytochrome c bacterial - - - 0.00005221 53.0
SX1_k127_3251975_9 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0002844 47.0
SX1_k127_3279547_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 501.0
SX1_k127_3279547_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 441.0
SX1_k127_3279547_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 396.0
SX1_k127_3279547_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 385.0
SX1_k127_3279547_4 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000007076 230.0
SX1_k127_3279547_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000855 158.0
SX1_k127_3279547_6 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000004511 129.0
SX1_k127_3279547_7 protein conserved in archaea - - - 0.000000000000000000000000003707 113.0
SX1_k127_332418_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 313.0
SX1_k127_332418_1 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001093 255.0
SX1_k127_332418_2 PFAM Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000004325 204.0
SX1_k127_332418_3 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000008265 167.0
SX1_k127_332418_4 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.00000000000000000000000001782 113.0
SX1_k127_332418_5 geranylgeranyl reductase K00311 - 1.5.5.1 0.0000000000000000001231 95.0
SX1_k127_332418_6 - - - - 0.000000000003716 78.0
SX1_k127_332418_7 Pfam:DUF552 K09152 - - 0.0000000007057 66.0
SX1_k127_332594_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.236e-255 804.0
SX1_k127_332594_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 489.0
SX1_k127_332594_10 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000005214 239.0
SX1_k127_332594_11 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000001627 214.0
SX1_k127_332594_12 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000004728 220.0
SX1_k127_332594_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000008135 205.0
SX1_k127_332594_14 ATP-grasp domain K06913 - - 0.0000000000000000000000000000000000000000000000000000001675 209.0
SX1_k127_332594_15 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000766 176.0
SX1_k127_332594_16 TIGRFAM molybdenum cofactor synthesis K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000001179 165.0
SX1_k127_332594_17 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.0000000000000000000000000000000000000000008956 166.0
SX1_k127_332594_18 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000009022 160.0
SX1_k127_332594_19 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000002473 147.0
SX1_k127_332594_2 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 452.0
SX1_k127_332594_20 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000007664 150.0
SX1_k127_332594_21 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000003637 117.0
SX1_k127_332594_22 Protein of unknown function (DUF1697) - - - 0.0000000000000000000001523 100.0
SX1_k127_332594_23 Starch synthase catalytic K16149 - 2.4.1.18 0.000000000000000007789 97.0
SX1_k127_332594_24 Rhomboid family K07059 - - 0.0000000000008401 73.0
SX1_k127_332594_25 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000001785 70.0
SX1_k127_332594_26 Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 - - 0.000000000006114 69.0
SX1_k127_332594_27 Domain of unknown function (DUF1610) K07580 - - 0.00000000003453 64.0
SX1_k127_332594_28 Putative zinc- or iron-chelating domain K06940 - - 0.00000001625 63.0
SX1_k127_332594_29 membrane-bound metal-dependent K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000103 53.0
SX1_k127_332594_3 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 402.0
SX1_k127_332594_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 392.0
SX1_k127_332594_5 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 391.0
SX1_k127_332594_6 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 368.0
SX1_k127_332594_7 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 360.0
SX1_k127_332594_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 327.0
SX1_k127_332594_9 SMART Elongator protein 3 MiaB NifB K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001053 273.0
SX1_k127_3340673_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 486.0
SX1_k127_3340673_1 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 346.0
SX1_k127_3340673_10 - - - - 0.0000000000000000000000000000000000000000000000007607 186.0
SX1_k127_3340673_11 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000002097 147.0
SX1_k127_3340673_12 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000007115 141.0
SX1_k127_3340673_13 PFAM response regulator receiver K07657,K07658 - - 0.0000000000000000000331 94.0
SX1_k127_3340673_14 - K00960 - 2.7.7.6 0.00000000000000002315 82.0
SX1_k127_3340673_15 E3 Ubiquitin ligase - - - 0.0000000000000001141 89.0
SX1_k127_3340673_16 integral membrane protein - - - 0.000000000000001421 89.0
SX1_k127_3340673_17 - - - - 0.00000000000001665 79.0
SX1_k127_3340673_18 H ACA RNA-protein complex K07569 - - 0.00000006877 57.0
SX1_k127_3340673_19 sister chromatid segregation - - - 0.000042 52.0
SX1_k127_3340673_2 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 306.0
SX1_k127_3340673_20 - - - - 0.00026 50.0
SX1_k127_3340673_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001739 280.0
SX1_k127_3340673_4 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000000001707 276.0
SX1_k127_3340673_5 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000002364 256.0
SX1_k127_3340673_6 DNA polymerase alpha chain like domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009311 246.0
SX1_k127_3340673_7 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000001824 229.0
SX1_k127_3340673_8 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000001325 200.0
SX1_k127_3340673_9 Necessary for normal cell division and for the maintenance of normal septation - - - 0.00000000000000000000000000000000000000000000000000002501 193.0
SX1_k127_3380180_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 6.103e-230 728.0
SX1_k127_3380180_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 550.0
SX1_k127_3380180_10 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 295.0
SX1_k127_3380180_11 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004236 273.0
SX1_k127_3380180_12 mature ribosome assembly K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007292 255.0
SX1_k127_3380180_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000473 209.0
SX1_k127_3380180_14 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000002241 197.0
SX1_k127_3380180_15 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000717 192.0
SX1_k127_3380180_16 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.000000000000000000000000000000000000000000000001999 181.0
SX1_k127_3380180_17 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.00000000000000000000000000000442 119.0
SX1_k127_3380180_18 50S ribosomal protein L37Ae K02921 - - 0.000000000000000000000000009486 111.0
SX1_k127_3380180_19 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000000764 93.0
SX1_k127_3380180_2 PFAM GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 432.0
SX1_k127_3380180_20 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000002202 92.0
SX1_k127_3380180_21 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.0000000000000000724 90.0
SX1_k127_3380180_22 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000006886 79.0
SX1_k127_3380180_23 Transcription factor Pcc1 K09741 - - 0.0000000004472 65.0
SX1_k127_3380180_24 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000004684 57.0
SX1_k127_3380180_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 424.0
SX1_k127_3380180_4 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 427.0
SX1_k127_3380180_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 359.0
SX1_k127_3380180_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 331.0
SX1_k127_3380180_7 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 341.0
SX1_k127_3380180_8 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 325.0
SX1_k127_3380180_9 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 291.0
SX1_k127_3424333_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 541.0
SX1_k127_3424333_1 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 454.0
SX1_k127_3424333_10 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000001585 178.0
SX1_k127_3424333_11 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000008007 121.0
SX1_k127_3424333_12 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000982 104.0
SX1_k127_3424333_13 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000008278 96.0
SX1_k127_3424333_2 hydrogenase expression formation protein K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 394.0
SX1_k127_3424333_3 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 361.0
SX1_k127_3424333_4 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 346.0
SX1_k127_3424333_5 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002346 267.0
SX1_k127_3424333_6 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
SX1_k127_3424333_7 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000085 255.0
SX1_k127_3424333_8 Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000004854 214.0
SX1_k127_3424333_9 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.00000000000000000000000000000000000000000000000006052 185.0
SX1_k127_3429122_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000001183 206.0
SX1_k127_3429122_1 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000000000000000000000000004796 191.0
SX1_k127_3429122_2 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.000000000000000000000000000000000000000002699 159.0
SX1_k127_3429122_3 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000001877 154.0
SX1_k127_3429122_4 VanZ like family - - - 0.0000000000000005566 83.0
SX1_k127_3429122_5 Belongs to the UPF0200 family - - - 0.000000000000001441 84.0
SX1_k127_3429122_6 but it may be involved in stabilization of the trimeric complex - - - 0.000007581 49.0
SX1_k127_3444829_0 DnaB-like helicase C terminal domain K08482 - - 0.00000000000000000000000000000008479 136.0
SX1_k127_3444829_1 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000001095 98.0
SX1_k127_3444829_3 ATP cone domain - - - 0.0007178 45.0
SX1_k127_3448901_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01531,K01535,K16905 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2,3.6.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 578.0
SX1_k127_3448901_1 PFAM Circadian clock protein KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 309.0
SX1_k127_3448901_11 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000000000002093 86.0
SX1_k127_3448901_19 thiamine diphosphate biosynthetic process K03154 - - 0.00005305 49.0
SX1_k127_3448901_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 293.0
SX1_k127_3448901_21 - - - - 0.00008775 46.0
SX1_k127_3448901_3 PP-loop family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002221 282.0
SX1_k127_3448901_4 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000001375 178.0
SX1_k127_3448901_5 Ribosomal protein S8e K02995 - - 0.0000000000000000000000000000000000001776 145.0
SX1_k127_3448901_8 - - - - 0.00000000000000000000000001382 111.0
SX1_k127_3448901_9 - - - - 0.00000000000000000000001742 100.0
SX1_k127_3479626_0 phosphohydrolase K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 313.0
SX1_k127_3479626_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000007278 199.0
SX1_k127_36353_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 604.0
SX1_k127_36353_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 565.0
SX1_k127_36353_10 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000007206 228.0
SX1_k127_36353_11 Flavoprotein K18853 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0042558,GO:0042559,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901283,GO:1901285,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:2001115,GO:2001116,GO:2001117,GO:2001118 1.5.99.15 0.00000000000000000000000000000000000000000000000000000000000006737 221.0
SX1_k127_36353_12 HI0933-like protein K13796 - - 0.00000000000000000000000000000000000000000000000000000000005172 215.0
SX1_k127_36353_13 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000001205 212.0
SX1_k127_36353_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000001621 195.0
SX1_k127_36353_15 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000001429 198.0
SX1_k127_36353_16 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000005285 175.0
SX1_k127_36353_17 - - - - 0.00000000000000000000000000000000000000000004647 173.0
SX1_k127_36353_18 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000002567 164.0
SX1_k127_36353_19 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000002052 149.0
SX1_k127_36353_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 551.0
SX1_k127_36353_20 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.000000000000000000000000000000000002957 141.0
SX1_k127_36353_21 Segregation and condensation complex subunit ScpB K06024 - - 0.00000000000000000000000000000002449 132.0
SX1_k127_36353_22 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000003367 119.0
SX1_k127_36353_23 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000001036 101.0
SX1_k127_36353_24 PAS PAC domain-like protein - - - 0.0000000000000000007366 96.0
SX1_k127_36353_25 - - - - 0.000000008418 64.0
SX1_k127_36353_26 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000001913 57.0
SX1_k127_36353_3 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 467.0
SX1_k127_36353_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 428.0
SX1_k127_36353_5 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 407.0
SX1_k127_36353_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 398.0
SX1_k127_36353_7 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 330.0
SX1_k127_36353_8 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 320.0
SX1_k127_36353_9 Fumarate hydratase K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001598 271.0
SX1_k127_3635409_0 Cell division protein 48, CDC48, domain 2 K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 564.0
SX1_k127_3635409_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 382.0
SX1_k127_3635409_2 helix_turn_helix, Arsenical Resistance Operon Repressor K07721 - - 0.00000000000000000000001924 106.0
SX1_k127_3635409_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000002389 93.0
SX1_k127_3635409_4 Psort location CytoplasmicMembrane, score - - - 0.0001364 55.0
SX1_k127_3710625_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000001233 226.0
SX1_k127_3710625_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K15553 - - 0.000000005709 66.0
SX1_k127_388400_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 508.0
SX1_k127_388400_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 376.0
SX1_k127_388400_2 - - - - 0.0000000000000006085 82.0
SX1_k127_388400_3 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000008941 59.0
SX1_k127_3994940_0 PFAM regulatory protein, ArsR - - - 0.0000000000000116 76.0
SX1_k127_3994940_1 - - - - 0.0000000001572 73.0
SX1_k127_3994940_2 - - - - 0.000006919 58.0
SX1_k127_3994940_3 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.0002687 53.0
SX1_k127_4039727_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 6.807e-304 952.0
SX1_k127_4039727_1 COG1138 Cytochrome c biogenesis factor K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 435.0
SX1_k127_4039727_10 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000006644 118.0
SX1_k127_4039727_11 metal-dependent protease of the PAD1 JAB1 superfamily K20110 - 3.4.19.15 0.00000000000000000000000001243 116.0
SX1_k127_4039727_12 Involved in regulation of DNA replication K10725 - - 0.0000000000001908 70.0
SX1_k127_4039727_13 4Fe-4S dicluster domain - - - 0.0000000000004052 74.0
SX1_k127_4039727_14 membrane-associated protein domain - - - 0.0000000003181 67.0
SX1_k127_4039727_15 AsnC family - - - 0.00000002423 58.0
SX1_k127_4039727_2 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 367.0
SX1_k127_4039727_3 KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000002201 237.0
SX1_k127_4039727_4 Hemerythrin HHE cation binding domain protein K09155 - - 0.00000000000000000000000000000000000000000000000000000002251 199.0
SX1_k127_4039727_5 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000001792 192.0
SX1_k127_4039727_6 COG0785 Cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000008472 192.0
SX1_k127_4039727_7 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000002076 197.0
SX1_k127_4039727_8 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000006651 162.0
SX1_k127_4039727_9 membrane - - - 0.00000000000000000000000000008034 123.0
SX1_k127_4075457_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 577.0
SX1_k127_4075457_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 527.0
SX1_k127_4075457_10 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000000000645 162.0
SX1_k127_4075457_11 Thioredoxin-like - - - 0.000000000000000000000000000000000000002011 165.0
SX1_k127_4075457_12 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000046 158.0
SX1_k127_4075457_13 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000004197 141.0
SX1_k127_4075457_14 Domain of unknown function (DUF371) K09738 - - 0.000000000000000000000000000000009313 134.0
SX1_k127_4075457_15 Acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000195 131.0
SX1_k127_4075457_16 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000003987 100.0
SX1_k127_4075457_17 signal transduction protein with CBS domains - - - 0.000000000000000000001009 100.0
SX1_k127_4075457_18 PFAM Uncharacterised protein family UPF0058 - - - 0.00000000000000000001405 94.0
SX1_k127_4075457_19 quorum sensing - - - 0.000000000000000000017 98.0
SX1_k127_4075457_2 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 376.0
SX1_k127_4075457_20 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000003643 71.0
SX1_k127_4075457_21 - - - - 0.00000002362 63.0
SX1_k127_4075457_22 Stage II sporulation protein M - - - 0.0003551 50.0
SX1_k127_4075457_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 336.0
SX1_k127_4075457_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008257 288.0
SX1_k127_4075457_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000003373 250.0
SX1_k127_4075457_6 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000001378 241.0
SX1_k127_4075457_7 Protein of unknown function (DUF530) K09724 - - 0.0000000000000000000000000000000000000000000000000000000000000001648 242.0
SX1_k127_4075457_8 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000001016 197.0
SX1_k127_4075457_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000000000000000000003834 192.0
SX1_k127_4192966_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000001177 233.0
SX1_k127_4192966_1 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000007851 213.0
SX1_k127_4192966_2 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000003255 213.0
SX1_k127_4192966_3 Functions by promoting the formation of the first peptide bond K03263 - - 0.00000000000000000000000000000000000000000000929 166.0
SX1_k127_4192966_4 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000000001239 167.0
SX1_k127_4192966_5 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000000005341 123.0
SX1_k127_4218493_0 LOR SDH bifunctional enzyme conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 506.0
SX1_k127_4218493_1 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 491.0
SX1_k127_4218493_2 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 463.0
SX1_k127_4218493_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 371.0
SX1_k127_4218493_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 326.0
SX1_k127_4218493_5 Helix-turn-helix domain K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001069 284.0
SX1_k127_4218493_6 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.000000000000000000000000000000000000000000000000000000000000000001783 238.0
SX1_k127_4218493_7 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000006844 178.0
SX1_k127_4280286_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.92e-238 750.0
SX1_k127_4280286_1 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 476.0
SX1_k127_4280286_10 Multisubunit na h antiporter, mnhf subunit K05570 - - 0.00000000000003127 76.0
SX1_k127_4280286_11 Domain of unknown function (DUF4040) - - - 0.0000000000001667 78.0
SX1_k127_4280286_12 - - - - 0.000005354 55.0
SX1_k127_4280286_2 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 454.0
SX1_k127_4280286_3 PFAM NADH Ubiquinone plastoquinone (complex I) K05568,K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 419.0
SX1_k127_4280286_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000000006669 130.0
SX1_k127_4280286_5 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.00000000000000000000000000001997 122.0
SX1_k127_4280286_6 Na+/H+ ion antiporter subunit - - - 0.00000000000000000000000000005203 122.0
SX1_k127_4280286_7 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.00000000000000000000000003384 116.0
SX1_k127_4280286_8 COG2111 Multisubunit Na H antiporter, MnhB subunit K05566 - - 0.0000000000000000000006325 100.0
SX1_k127_4280286_9 - - - - 0.000000000000002711 80.0
SX1_k127_4329842_0 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 388.0
SX1_k127_4329842_1 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 311.0
SX1_k127_4329842_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004022 276.0
SX1_k127_4329842_3 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001195 250.0
SX1_k127_4329842_4 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000001526 220.0
SX1_k127_4329842_5 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000002844 154.0
SX1_k127_4329842_6 cheY-homologous receiver domain K02485,K03413 - - 0.00000000000000000004055 95.0
SX1_k127_4329842_7 - - - - 0.00000000000006419 75.0
SX1_k127_4329842_8 PDGLE domain K02009 - - 0.0000000002547 71.0
SX1_k127_4387215_0 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 522.0
SX1_k127_4387215_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000007109 268.0
SX1_k127_4387215_2 Haloacid dehalogenase-like hydrolase K01101 - 3.1.3.41 0.00000000000000000000000000000000000000004671 160.0
SX1_k127_4401243_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 541.0
SX1_k127_4401243_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 484.0
SX1_k127_4401243_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 464.0
SX1_k127_4401243_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008055 407.0
SX1_k127_4401243_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000003056 261.0
SX1_k127_4401243_5 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000003232 240.0
SX1_k127_4401243_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000005606 177.0
SX1_k127_4401243_7 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.0000000000000000000002368 98.0
SX1_k127_4591242_0 DNA polymerase K02319 - 2.7.7.7 1.583e-202 656.0
SX1_k127_4591242_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 591.0
SX1_k127_4591242_10 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000001277 211.0
SX1_k127_4591242_11 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000833 195.0
SX1_k127_4591242_12 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000008884 149.0
SX1_k127_4591242_13 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000004359 141.0
SX1_k127_4591242_14 cheY-homologous receiver domain K07668 - - 0.000000000000000000000007054 109.0
SX1_k127_4591242_15 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000003543 102.0
SX1_k127_4591242_16 Protein of unknown function (DUF424) K09148 - - 0.0000000000000000002666 90.0
SX1_k127_4591242_17 CBS domain - - - 0.000000000000000001024 91.0
SX1_k127_4591242_18 PFAM thiamineS protein K03636 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000001585 92.0
SX1_k127_4591242_19 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.0000000000006403 72.0
SX1_k127_4591242_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 551.0
SX1_k127_4591242_20 Putative zinc- or iron-chelating domain K06940 - - 0.0000000002685 68.0
SX1_k127_4591242_21 protein conserved in archaea K09746 - - 0.00000000119 60.0
SX1_k127_4591242_3 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 441.0
SX1_k127_4591242_4 COG COG0436 Aspartate tyrosine aromatic aminotransferase K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 370.0
SX1_k127_4591242_5 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 293.0
SX1_k127_4591242_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009668 263.0
SX1_k127_4591242_7 PFAM ExsB family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000005609 239.0
SX1_k127_4591242_8 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000006282 233.0
SX1_k127_4591242_9 TIGRFAM Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000001484 218.0
SX1_k127_4602920_0 type II secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 469.0
SX1_k127_4602920_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 334.0
SX1_k127_4602920_10 rRNA binding K02944 - - 0.000000000000867 70.0
SX1_k127_4602920_11 membrane K06384 - - 0.000000000003117 76.0
SX1_k127_4602920_12 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000001192 70.0
SX1_k127_4602920_13 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000002599 66.0
SX1_k127_4602920_2 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000006152 221.0
SX1_k127_4602920_3 Asparagine synthase K07585 - - 0.0000000000000000000000000000000000000000000000000000000000006689 215.0
SX1_k127_4602920_4 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000000000006361 199.0
SX1_k127_4602920_5 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000004773 188.0
SX1_k127_4602920_6 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000008084 166.0
SX1_k127_4602920_7 tRNA-ribosyltransferase - - - 0.0000000000000000000000000000007691 133.0
SX1_k127_4602920_8 Belongs to the ribosomal protein L31e family K02910 - - 0.00000000000000000000000002834 112.0
SX1_k127_4602920_9 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000005605 93.0
SX1_k127_4756866_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 421.0
SX1_k127_4756866_1 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 396.0
SX1_k127_4756866_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000000000000000000000001912 185.0
SX1_k127_4756866_11 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000002768 187.0
SX1_k127_4756866_12 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000004914 179.0
SX1_k127_4756866_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000000000002239 180.0
SX1_k127_4756866_14 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000001345 168.0
SX1_k127_4756866_15 structural constituent of ribosome K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001264 161.0
SX1_k127_4756866_16 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000638 155.0
SX1_k127_4756866_17 - - - - 0.00000000000000000000000000000000007638 136.0
SX1_k127_4756866_18 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.000000000000000000000000000000164 126.0
SX1_k127_4756866_19 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000001669 115.0
SX1_k127_4756866_2 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 388.0
SX1_k127_4756866_20 cellulose 1,4-beta-cellobiosidase activity K01278,K01727,K03561,K12287,K21449 - 3.4.14.5,4.2.2.1 0.00000000000000000000000006929 119.0
SX1_k127_4756866_21 Peptidase S24-like K13280 - 3.4.21.89 0.000000000000000000000001083 109.0
SX1_k127_4756866_22 PFAM SpoVG K06412 - - 0.000000000000000000000006742 103.0
SX1_k127_4756866_23 Protein of unknown function DUF47 K07220 - - 0.000000000000000002126 88.0
SX1_k127_4756866_24 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000000866 87.0
SX1_k127_4756866_25 - K00960 - 2.7.7.6 0.00000000000000415 76.0
SX1_k127_4756866_26 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000003265 76.0
SX1_k127_4756866_27 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000001562 77.0
SX1_k127_4756866_28 Ribonuclease III - - - 0.00000000002781 74.0
SX1_k127_4756866_29 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000001378 69.0
SX1_k127_4756866_3 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 398.0
SX1_k127_4756866_30 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.00000001204 62.0
SX1_k127_4756866_31 Phosphate uptake regulator, PhoU - - - 0.000005983 58.0
SX1_k127_4756866_32 domain, Protein - - - 0.0001137 53.0
SX1_k127_4756866_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000004811 264.0
SX1_k127_4756866_5 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006402 258.0
SX1_k127_4756866_6 RNA polymerase K03049 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000001649 241.0
SX1_k127_4756866_7 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000002941 232.0
SX1_k127_4756866_8 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000000000000002738 205.0
SX1_k127_4756866_9 methyltransferase small K07579 - - 0.0000000000000000000000000000000000000000000000000005592 204.0
SX1_k127_4787077_0 Glycogen synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 610.0
SX1_k127_4787077_1 Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP K05716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 472.0
SX1_k127_4787077_10 PFAM plasmid stabilization system K06218 - - 0.0000000000000000000009762 97.0
SX1_k127_4787077_11 - - - - 0.0000000000003239 78.0
SX1_k127_4787077_12 PFAM PKD domain containing protein - - - 0.0001863 54.0
SX1_k127_4787077_2 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 387.0
SX1_k127_4787077_3 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005313 278.0
SX1_k127_4787077_4 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000001647 255.0
SX1_k127_4787077_5 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000002121 216.0
SX1_k127_4787077_6 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000000002169 190.0
SX1_k127_4787077_7 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000000006212 179.0
SX1_k127_4787077_8 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000008319 163.0
SX1_k127_4787077_9 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000103 162.0
SX1_k127_4857591_0 TIGRFAM glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 604.0
SX1_k127_4857591_1 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 519.0
SX1_k127_4857591_10 methylase K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000000000000000000000001083 248.0
SX1_k127_4857591_11 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000001311 244.0
SX1_k127_4857591_12 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000000000000000000001375 221.0
SX1_k127_4857591_13 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000001606 187.0
SX1_k127_4857591_14 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000004433 164.0
SX1_k127_4857591_15 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000009625 113.0
SX1_k127_4857591_16 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000001575 116.0
SX1_k127_4857591_17 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000002252 56.0
SX1_k127_4857591_18 Myosin heavy chain, fast skeletal muscle-like K10352,K17751 - - 0.000001881 60.0
SX1_k127_4857591_19 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000527 53.0
SX1_k127_4857591_2 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 434.0
SX1_k127_4857591_3 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 392.0
SX1_k127_4857591_4 Involved in cell shape control K22222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 379.0
SX1_k127_4857591_5 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 345.0
SX1_k127_4857591_6 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 331.0
SX1_k127_4857591_7 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 316.0
SX1_k127_4857591_8 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 308.0
SX1_k127_4857591_9 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 299.0
SX1_k127_4858521_0 Cell division protein 48 (CDC48) N-terminal domain K13525 - - 2.147e-302 946.0
SX1_k127_4858521_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 428.0
SX1_k127_4858521_2 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 390.0
SX1_k127_4858521_3 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 382.0
SX1_k127_4858521_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 380.0
SX1_k127_4858521_5 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000006025 240.0
SX1_k127_4858521_6 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000009282 233.0
SX1_k127_4858521_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000002213 117.0
SX1_k127_4858521_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000002874 87.0
SX1_k127_4858521_9 Protein of unknown function (DUF1525) - - - 0.000000000000001603 80.0
SX1_k127_4925780_0 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000002266 212.0
SX1_k127_4925780_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000006374 189.0
SX1_k127_4925780_2 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000002298 186.0
SX1_k127_4925780_3 Peptidase A24B, FlaK domain protein K07991 - 3.4.23.52 0.000000000000002225 84.0
SX1_k127_4959127_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 1.758e-223 720.0
SX1_k127_4959127_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 427.0
SX1_k127_4959127_2 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005124 253.0
SX1_k127_4959127_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000000000002794 218.0
SX1_k127_4959127_4 PFAM Polysulphide reductase, NrfD K04015 - - 0.00000000000000000000000002653 120.0
SX1_k127_4959127_5 SMART Elongator protein 3 MiaB NifB - - - 0.00000004283 54.0
SX1_k127_5010266_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 413.0
SX1_k127_5010266_1 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000004194 263.0
SX1_k127_5010266_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000003451 214.0
SX1_k127_5010266_3 - - - - 0.000000000000000000000009115 110.0
SX1_k127_5010266_4 membrane-associated protein domain - - - 0.000000000001111 74.0
SX1_k127_5010266_5 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.00000002672 55.0
SX1_k127_5066325_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 467.0
SX1_k127_5066325_1 PFAM Thiamine pyrophosphate enzyme, C-terminal K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 406.0
SX1_k127_5066325_10 PFAM regulatory protein, MarR - - - 0.0000004289 61.0
SX1_k127_5066325_11 PFAM regulatory protein, MarR - - - 0.0000004289 61.0
SX1_k127_5066325_12 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000009817 54.0
SX1_k127_5066325_13 MazG nucleotide pyrophosphohydrolase domain - - - 0.0007284 46.0
SX1_k127_5066325_2 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 - 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 317.0
SX1_k127_5066325_3 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000253 191.0
SX1_k127_5066325_4 zinc metalloprotease whose natural substrate is K06974 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000004396 145.0
SX1_k127_5066325_5 Pyruvate:ferredoxin oxidoreductase core domain II K00169 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.000000000000000000000000000002458 123.0
SX1_k127_5066325_6 Domain of unknown function (DUF1805) - - - 0.00000000000000000000000003727 110.0
SX1_k127_5066325_7 Belongs to the UPF0146 family K09713 - - 0.00000000000000000000000007464 112.0
SX1_k127_5066325_8 cheY-homologous receiver domain K07668 - - 0.000000000000000000000001119 116.0
SX1_k127_5066325_9 - - - - 0.0000000000000000002035 103.0
SX1_k127_5069142_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.473e-228 732.0
SX1_k127_5069142_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 571.0
SX1_k127_5069142_2 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 493.0
SX1_k127_5069142_3 Belongs to the UPF0282 family K07022 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 358.0
SX1_k127_5069142_4 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000002577 243.0
SX1_k127_5069142_5 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000001354 203.0
SX1_k127_5069142_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000009396 162.0
SX1_k127_5069142_7 phosphoesterase RecJ domain protein - - - 0.0000000000000000000000000000001593 128.0
SX1_k127_5069142_8 t-RNA-binding domain protein K01874,K06878 - 6.1.1.10 0.00000000000000000000000000005773 124.0
SX1_k127_5069142_9 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.000000000000000000004932 102.0
SX1_k127_5160476_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 444.0
SX1_k127_5160476_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 376.0
SX1_k127_5160476_2 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 338.0
SX1_k127_5160476_3 Imidazole acetol-phosphate transaminase K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004387 287.0
SX1_k127_5160476_4 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000009312 236.0
SX1_k127_5160476_5 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000006979 175.0
SX1_k127_5160476_6 PFAM ATP-binding region, ATPase domain protein K07636,K07652 - 2.7.13.3 0.00000000000000000000000000000000000006125 166.0
SX1_k127_5160476_7 cheY-homologous receiver domain K07668 - - 0.000000000000000000000001903 107.0
SX1_k127_5290364_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 587.0
SX1_k127_5290364_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 561.0
SX1_k127_5290364_10 PFAM H transporting two-sector ATPase C subunit K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 - 0.0000000000000000000000000005451 122.0
SX1_k127_5290364_11 phosphorelay signal transduction system K07658 - - 0.00000000000000000000005762 112.0
SX1_k127_5290364_12 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000004815 72.0
SX1_k127_5290364_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000741 74.0
SX1_k127_5290364_14 diguanylate cyclase - - - 0.0000000003034 68.0
SX1_k127_5290364_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000009533 64.0
SX1_k127_5290364_2 Molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 347.0
SX1_k127_5290364_3 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 317.0
SX1_k127_5290364_4 Acyl-CoA synthetase (NDP forming) K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001086 274.0
SX1_k127_5290364_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008106 241.0
SX1_k127_5290364_6 CoA-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000005177 201.0
SX1_k127_5290364_7 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000001348 200.0
SX1_k127_5290364_8 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000002485 167.0
SX1_k127_5290364_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000009216 131.0
SX1_k127_532645_0 - - - - 0.00000000000000000000000000000000000000000000000000000000001147 216.0
SX1_k127_532645_1 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000234 202.0
SX1_k127_532645_2 PAS domain - - - 0.00000000003904 65.0
SX1_k127_5336764_0 small GTP-binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 424.0
SX1_k127_5336764_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002406 242.0
SX1_k127_5336764_2 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000001057 235.0
SX1_k127_5336764_3 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000000000000000000000000000000008555 194.0
SX1_k127_5336764_4 methyltransferase MtaA CmuA family - - - 0.00000000000000000000000000000000000000003956 168.0
SX1_k127_5336764_5 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K00548 - 2.1.1.13 0.00000000000000000000000000000000002039 139.0
SX1_k127_5336764_6 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000004723 104.0
SX1_k127_5336764_7 PFAM response regulator receiver K02485,K03413 - - 0.00000000000000000009727 93.0
SX1_k127_5336764_8 domain protein - - - 0.000000000000004286 78.0
SX1_k127_5336764_9 PFAM Methyltransferase type 11 - - - 0.00000000000819 76.0
SX1_k127_5399944_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 556.0
SX1_k127_5399944_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 508.0
SX1_k127_5399944_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 398.0
SX1_k127_5399944_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001571 285.0
SX1_k127_5399944_4 Thermophilic metalloprotease (M29) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001151 278.0
SX1_k127_5399944_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000469 233.0
SX1_k127_5399944_6 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000004744 191.0
SX1_k127_5399944_7 TIGRFAM Asp-tRNA(Asn) Glu-tRNA(Gln) amidotransferase, subunit C K02435 - 6.3.5.6,6.3.5.7 0.00000001594 59.0
SX1_k127_5551832_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1024.0
SX1_k127_5551832_1 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000008964 198.0
SX1_k127_5551832_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0001133 44.0
SX1_k127_5558199_0 Peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000001819 218.0
SX1_k127_5558199_1 TatD related DNase K07049 - - 0.00000000000000000000000001417 109.0
SX1_k127_5558199_2 PUA domain K07565 - - 0.000000000000000001306 92.0
SX1_k127_5558199_3 PFAM Nucleotide-binding protein, PIN domain - - - 0.00000000003386 68.0
SX1_k127_5558199_4 - - - - 0.00000004569 57.0
SX1_k127_5571143_0 CorA-like Mg2+ transporter protein K03284 GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 477.0
SX1_k127_5571143_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 346.0
SX1_k127_5571143_10 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000001496 78.0
SX1_k127_5571143_11 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000004942 77.0
SX1_k127_5571143_12 Cobalamin biosynthesis protein CbiX - - - 0.000001948 58.0
SX1_k127_5571143_2 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 306.0
SX1_k127_5571143_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003263 283.0
SX1_k127_5571143_4 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000005413 243.0
SX1_k127_5571143_5 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000001493 250.0
SX1_k127_5571143_6 Protein of unknown function (DUF432) K09149 - - 0.000000000000000000000000000000000000000000000000000000513 201.0
SX1_k127_5571143_7 Histidine kinase A domain protein K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000001837 197.0
SX1_k127_5571143_8 Transcriptional regulator, BadM Rrf2 family - - - 0.0000000000000000000000000000000000000000001995 162.0
SX1_k127_5571143_9 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000001229 143.0
SX1_k127_5586538_0 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 521.0
SX1_k127_5586538_1 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 511.0
SX1_k127_5586538_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 450.0
SX1_k127_5586538_3 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 376.0
SX1_k127_5586538_4 LysE type translocator - - - 0.000000000000000000000000000000000000000000000001996 181.0
SX1_k127_5586538_5 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000621 182.0
SX1_k127_5586538_6 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000001986 156.0
SX1_k127_5586538_7 Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000841 107.0
SX1_k127_5602618_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 425.0
SX1_k127_5602618_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 391.0
SX1_k127_5602618_10 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate family K00171 - 1.2.7.1 0.00000000000000000000000006402 109.0
SX1_k127_5602618_11 CBS domain - - - 0.000000000000000000000009554 107.0
SX1_k127_5602618_12 subunit (C K02119 - - 0.0000000000000000000009574 107.0
SX1_k127_5602618_13 PFAM CBS domain containing protein - - - 0.00000000000000002405 88.0
SX1_k127_5602618_14 ATP synthase subunit C K02124 - - 0.00000001549 61.0
SX1_k127_5602618_15 Snare associated golgi protein - - - 0.00000004649 61.0
SX1_k127_5602618_2 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 302.0
SX1_k127_5602618_3 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 - 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006765 282.0
SX1_k127_5602618_4 Belongs to the UPF0285 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007979 286.0
SX1_k127_5602618_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001823 271.0
SX1_k127_5602618_6 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000008209 231.0
SX1_k127_5602618_7 V-type ATPase 116kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000007462 218.0
SX1_k127_5602618_8 Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000009265 163.0
SX1_k127_5602618_9 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000002805 122.0
SX1_k127_5605890_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000003453 114.0
SX1_k127_5605890_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000001094 121.0
SX1_k127_5605890_2 cobalamin binding K00548 - 2.1.1.13 0.000000000000000000000518 101.0
SX1_k127_5629632_0 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 361.0
SX1_k127_5629632_1 COG1148 Heterodisulfide reductase, subunit A and related polyferredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000003733 254.0
SX1_k127_5629632_2 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000006925 212.0
SX1_k127_5629632_3 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000004881 166.0
SX1_k127_5629632_4 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000003681 134.0
SX1_k127_5629632_5 - - - - 0.000000000000000000000000008027 114.0
SX1_k127_5629632_6 Cytochrome C biogenesis protein transmembrane region - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000505 118.0
SX1_k127_5629632_7 component of anaerobic dehydrogenases - - - 0.00000000000000005899 89.0
SX1_k127_5629632_8 Cytochrome c554 and c-prime - - - 0.000000000001309 72.0
SX1_k127_5674039_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 509.0
SX1_k127_5674039_1 shikimate kinase activity K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000002737 250.0
SX1_k127_5674039_2 PFAM Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000002164 225.0
SX1_k127_5674039_3 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000002599 210.0
SX1_k127_5674039_4 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000002725 211.0
SX1_k127_5674039_5 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000002591 156.0
SX1_k127_5681825_0 PFAM DNA polymerase, beta domain protein region K09717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006011 264.0
SX1_k127_5681825_1 Cytochrome c554 and c-prime - - - 0.00000006275 57.0
SX1_k127_5681825_2 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity K00549 - 2.1.1.14 0.0000002482 55.0
SX1_k127_5681825_3 Rubrerythrin - - - 0.0001317 53.0
SX1_k127_5686993_0 CarboxypepD_reg-like domain - - - 0.000000000000009319 87.0
SX1_k127_5720403_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1175.0
SX1_k127_5720403_1 TCP-1/cpn60 chaperonin family K22447 - - 3.104e-214 677.0
SX1_k127_5720403_10 - - - - 0.0000000000000000000000000000000000000005464 169.0
SX1_k127_5720403_11 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000001868 137.0
SX1_k127_5720403_12 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000006465 131.0
SX1_k127_5720403_13 DNA polymerase family B K02319 - 2.7.7.7 0.0000009973 51.0
SX1_k127_5720403_2 Type II/IV secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 470.0
SX1_k127_5720403_3 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 396.0
SX1_k127_5720403_4 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 383.0
SX1_k127_5720403_5 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 340.0
SX1_k127_5720403_6 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.000000000000000000000000000000000000000000000000000000000000000000001041 243.0
SX1_k127_5720403_7 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000000000002019 213.0
SX1_k127_5720403_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000002095 196.0
SX1_k127_5720403_9 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000001673 179.0
SX1_k127_5796354_0 HMGL-like K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 566.0
SX1_k127_5796354_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 499.0
SX1_k127_5796354_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002849 284.0
SX1_k127_5820270_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.757e-298 928.0
SX1_k127_5820270_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 304.0
SX1_k127_5820270_2 ATP cone domain K05715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006073 279.0
SX1_k127_5820270_3 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000402 248.0
SX1_k127_5820270_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000001628 196.0
SX1_k127_5820270_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000005674 82.0
SX1_k127_5820270_6 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.00000000001201 69.0
SX1_k127_5820270_7 KEOPS complex Cgi121-like subunit K09119 - - 0.00000004396 61.0
SX1_k127_5889859_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1169.0
SX1_k127_5889859_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 1.09e-308 960.0
SX1_k127_5889859_10 PFAM transferase hexapeptide repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000066 253.0
SX1_k127_5889859_11 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001569 228.0
SX1_k127_5889859_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000003924 225.0
SX1_k127_5889859_13 Tubulin/FtsZ family, GTPase domain K22222 - - 0.000000000000000000000000000000000000000000000000000000000000004281 234.0
SX1_k127_5889859_14 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000001949 218.0
SX1_k127_5889859_15 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000001417 158.0
SX1_k127_5889859_16 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000005067 154.0
SX1_k127_5889859_17 PFAM regulatory protein AsnC Lrp family K03718 - - 0.000000000000000000000000000000000005158 141.0
SX1_k127_5889859_18 Nitroreductase family - - - 0.00000000000000000000000000000004053 128.0
SX1_k127_5889859_19 structural constituent of ribosome K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000004595 102.0
SX1_k127_5889859_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 - 2.7.7.6 1.437e-268 840.0
SX1_k127_5889859_20 - - - - 0.000000000000000000003429 98.0
SX1_k127_5889859_21 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000001232 73.0
SX1_k127_5889859_22 - - - - 0.0000000002668 73.0
SX1_k127_5889859_23 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000006988 68.0
SX1_k127_5889859_24 extracellular matrix structural constituent - - - 0.000000007461 69.0
SX1_k127_5889859_25 WD-40 repeat - - - 0.0000001747 65.0
SX1_k127_5889859_26 - - - - 0.00004191 56.0
SX1_k127_5889859_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 611.0
SX1_k127_5889859_4 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 588.0
SX1_k127_5889859_5 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 566.0
SX1_k127_5889859_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 412.0
SX1_k127_5889859_7 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 346.0
SX1_k127_5889859_8 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 291.0
SX1_k127_5889859_9 PFAM SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 289.0
SX1_k127_5943430_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 303.0
SX1_k127_5943430_1 PFAM ABC transporter K02003,K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005911 269.0
SX1_k127_5943430_2 diphthine-ammonia ligase activity K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000007793 216.0
SX1_k127_5943430_3 COG1361 S-layer domain - - - 0.000000000000000000000000006546 126.0
SX1_k127_5943430_4 membrane-associated protein domain - - - 0.0000000000004474 75.0
SX1_k127_6113621_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 611.0
SX1_k127_6113621_1 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001272 278.0
SX1_k127_6113621_2 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000006947 210.0
SX1_k127_6113621_3 OB-fold nucleic acid binding domain K09746 - - 0.000000000000000000005705 98.0
SX1_k127_61381_0 Nitroreductase family - - - 0.0000000000000000000000000000007272 124.0
SX1_k127_61381_1 Signal Transduction Histidine Kinase - - - 0.0000000000000000000001597 102.0
SX1_k127_622513_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002219 271.0
SX1_k127_622513_1 Protein of unknown function (DUF354) K09726 - - 0.00000000000000000000000000000000000000000000000000000000002548 227.0
SX1_k127_622513_2 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000003126 200.0
SX1_k127_622513_3 Glycosyl transferase family 4 K01001 - 2.7.8.15 0.000000000000000000000000000000000000000000000000000001941 202.0
SX1_k127_622513_4 Endonuclease V K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000005321 179.0
SX1_k127_622513_5 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.000000000000000000000000000000000000000000002232 170.0
SX1_k127_622513_6 - - - - 0.00000001428 62.0
SX1_k127_791303_0 Pheromone shutdown - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 313.0
SX1_k127_791303_1 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001935 277.0
SX1_k127_791303_10 PFAM peptidase M50 - - - 0.00000000001145 68.0
SX1_k127_791303_11 PRC-barrel domain - - - 0.0000001295 57.0
SX1_k127_791303_12 PFAM Class III signal peptide - - - 0.0001291 46.0
SX1_k127_791303_2 TIGRFAM riboflavin-specific deaminase C-terminal K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000000000000001744 253.0
SX1_k127_791303_3 IMG reference gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000003856 250.0
SX1_k127_791303_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000002029 216.0
SX1_k127_791303_5 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000006123 219.0
SX1_k127_791303_6 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000002335 186.0
SX1_k127_791303_7 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000000000000000000000000000000000001354 175.0
SX1_k127_791303_8 Type II secretion system (T2SS), protein F - - - 0.00000000000000000000000000000000000000002274 164.0
SX1_k127_791303_9 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000002478 122.0
SX1_k127_809385_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 4.666e-196 615.0
SX1_k127_809385_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 409.0
SX1_k127_809385_10 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000007203 188.0
SX1_k127_809385_11 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000004359 139.0
SX1_k127_809385_12 Protein of unknown function (DUF531) K09725 - - 0.00000000000000000000000000000000473 140.0
SX1_k127_809385_13 PhoU domain - - - 0.0000000000000000002165 96.0
SX1_k127_809385_14 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000001381 54.0
SX1_k127_809385_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 327.0
SX1_k127_809385_3 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 292.0
SX1_k127_809385_4 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001301 287.0
SX1_k127_809385_5 ADP-specific Phosphofructokinase/Glucokinase conserved region K00918 - 2.7.1.146,2.7.1.147 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001455 286.0
SX1_k127_809385_6 phosphate symporter K14683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002476 273.0
SX1_k127_809385_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005524 263.0
SX1_k127_809385_8 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000001978 243.0
SX1_k127_809385_9 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000176 225.0
SX1_k127_815091_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 2.233e-275 872.0
SX1_k127_815091_1 TIGRFAM small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 393.0
SX1_k127_815091_10 - - - - 0.000000001872 64.0
SX1_k127_815091_2 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 360.0
SX1_k127_815091_3 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000001415 213.0
SX1_k127_815091_4 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.00000000000000000000000000000000000000000000000000001059 194.0
SX1_k127_815091_5 PQQ-like domain - - - 0.0000000000000000000000000002195 128.0
SX1_k127_815091_6 toxin-antitoxin pair type II binding - - - 0.00000000000000000000003578 101.0
SX1_k127_815091_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K20201 - 3.1.3.48,3.9.1.2 0.0000000000000000000004407 101.0
SX1_k127_815091_8 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000007025 90.0
SX1_k127_815091_9 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000003328 76.0
SX1_k127_821331_0 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000242 169.0
SX1_k127_821331_1 membrane - - - 0.000000000000000000000002693 113.0
SX1_k127_843593_0 type II secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 578.0
SX1_k127_843593_1 secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 483.0
SX1_k127_843593_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 386.0
SX1_k127_843593_3 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000007658 227.0
SX1_k127_843593_4 Protein of unknown function (DUF515) - - - 0.0000000000008776 80.0
SX1_k127_898088_0 Belongs to the TCP-1 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.963e-233 734.0
SX1_k127_898088_1 ORF6N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 388.0
SX1_k127_898088_10 - - - - 0.0000002517 62.0
SX1_k127_898088_11 peptidyl-tyrosine sulfation - - - 0.000004973 58.0
SX1_k127_898088_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003356 286.0
SX1_k127_898088_3 Protein-export membrane protein SecD K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001034 283.0
SX1_k127_898088_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000001059 194.0
SX1_k127_898088_5 - - - - 0.00000000000000000000000000000000000000000000005517 174.0
SX1_k127_898088_6 Involved in protein export K03074 - - 0.00000000000000000000000000000000000000004278 162.0
SX1_k127_898088_7 Glutaredoxin - - - 0.0000000000000000004806 89.0
SX1_k127_898088_8 Pkd domain containing protein - - - 0.000000000000007592 86.0
SX1_k127_898088_9 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000001287 59.0