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Overview

ID MAG03628
Name SX1_bin.54
Sample SMP0091
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family JACTUA01
Genus JAJRCM01
Species
Assembly information
Completeness (%) 74.19
Contamination (%) 0.36
GC content (%) 53.0
N50 (bp) 4,166
Genome size (bp) 1,212,428

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1475

Gene name Description KEGG GOs EC E-value Score Sequence
SX1_k127_1062616_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 6.216e-243 762.0
SX1_k127_1062616_1 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 526.0
SX1_k127_1084307_0 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 297.0
SX1_k127_1084307_1 - - - - 0.000000000000000000000000000001313 123.0
SX1_k127_1084307_2 PFAM amidohydrolase - - - 0.0000000000000000000000000005433 117.0
SX1_k127_1084307_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000009246 74.0
SX1_k127_1084307_4 Involved in protein export. The function of the beta subunit is - GO:0003674,GO:0005085,GO:0005086,GO:0005488,GO:0005515,GO:0008150,GO:0019899,GO:0051020,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000009246 74.0
SX1_k127_1095404_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 527.0
SX1_k127_1095404_1 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 399.0
SX1_k127_1095404_2 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 304.0
SX1_k127_1095404_3 - - - - 0.00000000000000000000000000000005091 136.0
SX1_k127_1122570_0 methanogenesis marker protein 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 423.0
SX1_k127_1122570_1 - - - - 0.0000000000000000000000000000000000000000000002653 168.0
SX1_k127_1122570_2 - - - - 0.0000000000000000000003366 100.0
SX1_k127_1122570_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000001438 68.0
SX1_k127_1132787_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 364.0
SX1_k127_1132787_1 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 349.0
SX1_k127_1132787_2 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000007068 235.0
SX1_k127_1132787_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000007305 226.0
SX1_k127_1132787_4 - - - - 0.0002009 46.0
SX1_k127_1137695_0 PFAM Thiolase K00626 - 2.3.1.9 2.935e-204 640.0
SX1_k127_1137695_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000001501 190.0
SX1_k127_1137695_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000001207 100.0
SX1_k127_1172258_0 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 308.0
SX1_k127_1172258_1 - - - - 0.00000000000000000000000000000000000403 139.0
SX1_k127_1172258_2 - - - - 0.00000000000000000000000000000006129 134.0
SX1_k127_1172258_3 - - - - 0.00000000000000000004489 96.0
SX1_k127_1180310_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 507.0
SX1_k127_1180310_1 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000001316 114.0
SX1_k127_1213821_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 383.0
SX1_k127_1213821_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000008666 116.0
SX1_k127_1235469_0 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 367.0
SX1_k127_1235469_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000000000004774 173.0
SX1_k127_1235469_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.000000000000000000000000000000000000000000002691 164.0
SX1_k127_1235469_3 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.00000000000000000000001056 102.0
SX1_k127_1281010_0 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 572.0
SX1_k127_1281010_1 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 539.0
SX1_k127_1281010_2 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18023 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000009883 241.0
SX1_k127_1281010_3 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K18017 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000002237 218.0
SX1_k127_1281010_4 - - - - 0.00000000000000000000000000000000000001425 146.0
SX1_k127_1293912_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 362.0
SX1_k127_1293912_1 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000003652 173.0
SX1_k127_1370519_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 571.0
SX1_k127_1370519_1 PFAM ABC transporter related K02068,K03529,K06166,K16786,K16787 - 2.7.8.37 0.0000000000000000000000000000000000000000000000000000000000000000000000164 248.0
SX1_k127_1370519_2 PFAM ABC transporter K16786 - - 0.000000000000000000000000000006072 121.0
SX1_k127_1371749_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 306.0
SX1_k127_1371749_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 292.0
SX1_k127_1371749_2 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000406 213.0
SX1_k127_1379973_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.715e-234 730.0
SX1_k127_1379973_1 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 418.0
SX1_k127_1379973_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 310.0
SX1_k127_1379973_4 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000001961 194.0
SX1_k127_1379973_5 - - - - 0.00001457 51.0
SX1_k127_1383812_0 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00125 - 1.17.1.9 3.029e-217 679.0
SX1_k127_1383812_1 amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000001419 202.0
SX1_k127_1383812_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000003754 159.0
SX1_k127_1391171_0 PFAM PUA domain containing protein K07557 - 2.6.1.97 7.331e-194 623.0
SX1_k127_1391171_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.00000000000000000000000008787 109.0
SX1_k127_1391171_2 Sulfide dehydrogenase (Flavoprotein) subunit SudB K00528,K02823 - 1.18.1.2,1.19.1.1 0.00000000000000000000015 98.0
SX1_k127_1414_0 PFAM Beta propeller domain K14475 - - 7.118e-211 673.0
SX1_k127_1414_1 PFAM Methyltransferase type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 311.0
SX1_k127_1414_2 membrane K09167 - - 0.00000000000000000000000000000000000000000000000445 179.0
SX1_k127_1430436_0 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 2.38e-244 762.0
SX1_k127_1430436_1 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.000000000000000000000000000000000000054 144.0
SX1_k127_1461916_0 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 357.0
SX1_k127_1461916_1 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 314.0
SX1_k127_1461916_2 PFAM Methyl-coenzyme M reductase, protein D K03422 - - 0.0000000000000000000000000406 109.0
SX1_k127_1512562_0 PFAM aminotransferase class V - - - 6.735e-201 631.0
SX1_k127_1512562_1 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 366.0
SX1_k127_1512562_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000007544 189.0
SX1_k127_1512562_3 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.000000000000000000000000208 105.0
SX1_k127_1559737_0 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 345.0
SX1_k127_1559737_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003741 296.0
SX1_k127_1559737_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000009765 107.0
SX1_k127_1559737_3 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.000000000006031 66.0
SX1_k127_1600791_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 564.0
SX1_k127_1600791_1 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 475.0
SX1_k127_1600791_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 357.0
SX1_k127_1600791_3 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000000000003706 178.0
SX1_k127_1630499_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 511.0
SX1_k127_1630499_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 456.0
SX1_k127_1630499_2 phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000008077 248.0
SX1_k127_1652590_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 8.673e-275 859.0
SX1_k127_1652590_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 517.0
SX1_k127_1652590_2 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.00000000000000000000000000000000000000005254 156.0
SX1_k127_1652799_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000006757 262.0
SX1_k127_1652799_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000002792 128.0
SX1_k127_1662646_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 517.0
SX1_k127_1662646_1 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005304 278.0
SX1_k127_1662646_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001648 259.0
SX1_k127_1662646_3 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000001315 164.0
SX1_k127_1664043_0 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 1.003e-294 912.0
SX1_k127_1664043_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.989e-270 833.0
SX1_k127_1664043_2 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 5.08e-234 729.0
SX1_k127_1664043_3 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 6.738e-206 646.0
SX1_k127_1664043_4 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 389.0
SX1_k127_1664043_5 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002333 251.0
SX1_k127_1664043_6 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000188 211.0
SX1_k127_1665868_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 402.0
SX1_k127_1665868_1 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 304.0
SX1_k127_1665868_2 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 286.0
SX1_k127_1665868_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004639 274.0
SX1_k127_1665868_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000000000000000000001712 113.0
SX1_k127_1687835_0 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 485.0
SX1_k127_1687835_1 Nitrogen regulatory protein P-II K04751 - - 0.000000000000002827 76.0
SX1_k127_1689883_0 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 453.0
SX1_k127_1689883_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 393.0
SX1_k127_1689883_10 - - - - 0.000006607 51.0
SX1_k127_1689883_2 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 395.0
SX1_k127_1689883_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 374.0
SX1_k127_1689883_4 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.00000000000000000000000000000000000000000000000000000000000004671 219.0
SX1_k127_1689883_5 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000622 220.0
SX1_k127_1689883_6 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000117 194.0
SX1_k127_1689883_7 protein conserved in archaea - - - 0.0000000000000000000000000001726 117.0
SX1_k127_1689883_8 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000000000002116 93.0
SX1_k127_1689883_9 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.000000000000000002018 85.0
SX1_k127_1696061_0 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 445.0
SX1_k127_1696061_1 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 425.0
SX1_k127_1696061_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 312.0
SX1_k127_1762429_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1126.0
SX1_k127_1762429_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 1.627e-249 779.0
SX1_k127_1762429_2 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 464.0
SX1_k127_1762429_3 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 414.0
SX1_k127_1762429_4 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000005101 209.0
SX1_k127_1762429_5 Protein of unknown function (DUF1295) - - - 0.00006235 51.0
SX1_k127_1785368_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 357.0
SX1_k127_1785368_1 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 289.0
SX1_k127_1785368_2 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000209 246.0
SX1_k127_1785368_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000000000000000000000006098 122.0
SX1_k127_1785368_4 RNA-binding protein involved in rRNA processing K07569 - - 0.0000000000000000007642 90.0
SX1_k127_1817257_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 604.0
SX1_k127_1817257_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 408.0
SX1_k127_1817257_2 Ferritin-like domain K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000000000000005796 223.0
SX1_k127_1817257_3 - - - - 0.0000000000008283 71.0
SX1_k127_1817257_4 - - - - 0.0000000007151 59.0
SX1_k127_1820202_0 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 374.0
SX1_k127_1820202_1 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000000003622 235.0
SX1_k127_1820202_2 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000003948 216.0
SX1_k127_1820202_3 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000002526 75.0
SX1_k127_1842459_0 COG0863 DNA modification methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 380.0
SX1_k127_1842459_1 PFAM ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 361.0
SX1_k127_1842459_2 PFAM SufBD protein K07033 - - 0.000000000000000000000000000000000000000000000000000000000000000329 226.0
SX1_k127_1862789_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 5.591e-227 714.0
SX1_k127_1862789_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 321.0
SX1_k127_1862789_2 Protein of unknown function (DUF432) K09149 - - 0.0000000000000000000000000000000000000000000000000000000004223 210.0
SX1_k127_1862789_3 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000177 118.0
SX1_k127_1862789_4 - - - - 0.00000000000000000000001272 108.0
SX1_k127_1862789_5 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000002468 100.0
SX1_k127_1862789_6 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000103 74.0
SX1_k127_1868280_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.91e-241 754.0
SX1_k127_1868280_1 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.0000000000000000003774 89.0
SX1_k127_1909804_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 477.0
SX1_k127_1909804_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 346.0
SX1_k127_1909804_2 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000007425 138.0
SX1_k127_1911603_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 3.835e-199 632.0
SX1_k127_1911603_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 610.0
SX1_k127_1911603_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 445.0
SX1_k127_1911603_3 ZPR1-related zinc finger protein K06874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000002334 136.0
SX1_k127_1916435_0 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 429.0
SX1_k127_1916435_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 408.0
SX1_k127_1916435_2 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000004375 219.0
SX1_k127_1916435_3 HAD-hyrolase-like K07025 - - 0.00000000000000000000000000000000000000000000000000000000000001568 223.0
SX1_k127_1916435_4 Fe-S-cluster oxidoreductase - - - 0.0000000000000000000000000000000000000000000009311 169.0
SX1_k127_1916435_5 Lon protease (S16) C-terminal proteolytic domain - - - 0.00000000000000000000000000000000000000000002485 165.0
SX1_k127_1916435_6 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0000000000000000000000000000000000000000849 161.0
SX1_k127_1916435_7 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000009582 95.0
SX1_k127_1916435_8 - - - - 0.000000000000009319 84.0
SX1_k127_1916435_9 redox protein regulator of disulfide bond formation - - - 0.0000004489 54.0
SX1_k127_193444_0 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 446.0
SX1_k127_193444_1 - - - - 0.000000000000000000000000000001072 123.0
SX1_k127_1951587_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1044.0
SX1_k127_1951587_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 306.0
SX1_k127_1951587_2 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001091 272.0
SX1_k127_1951587_3 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000007785 213.0
SX1_k127_1951587_4 SOS response associated peptidase (SRAP) - - - 0.000000005052 59.0
SX1_k127_1952491_0 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 1.839e-292 906.0
SX1_k127_1952491_1 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 5.394e-203 640.0
SX1_k127_1952491_2 4Fe-4S dicluster domain K11260,K14107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 286.0
SX1_k127_1952491_3 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.000000000000000000000000000006561 119.0
SX1_k127_1952491_4 Formylmethanofuran dehydrogenase subunit D K00203 - 1.2.7.12 0.0000000000000000003143 93.0
SX1_k127_1960896_0 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 447.0
SX1_k127_1960896_1 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.00000000000000000003724 91.0
SX1_k127_1964128_0 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 485.0
SX1_k127_1964128_1 Nitrogenase component 1 type Oxidoreductase K02591 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 362.0
SX1_k127_1964128_2 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000000000000000000004722 166.0
SX1_k127_1964128_3 Matrixin - - - 0.0000009973 51.0
SX1_k127_1979061_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 2.273e-239 746.0
SX1_k127_1979061_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 458.0
SX1_k127_1995677_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.295e-253 791.0
SX1_k127_1995677_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.055e-242 760.0
SX1_k127_1995677_10 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000001284 109.0
SX1_k127_1995677_11 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000002977 110.0
SX1_k127_1995677_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000002051 113.0
SX1_k127_1995677_13 ThiS family K03636 - - 0.000000000000000000000001108 106.0
SX1_k127_1995677_14 Ferredoxin K05337 - - 0.0000000000000000006171 88.0
SX1_k127_1995677_15 PspC domain K03973 - - 0.00000000000000001217 84.0
SX1_k127_1995677_16 PFAM UspA - - - 0.000000000000001618 82.0
SX1_k127_1995677_17 - - - - 0.000000000000004133 82.0
SX1_k127_1995677_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 454.0
SX1_k127_1995677_3 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 307.0
SX1_k127_1995677_4 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 314.0
SX1_k127_1995677_5 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
SX1_k127_1995677_6 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000002284 205.0
SX1_k127_1995677_7 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000000000001924 203.0
SX1_k127_1995677_8 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000005785 183.0
SX1_k127_1995677_9 AMP binding - - - 0.0000000000000000000000000000000000000000000000001854 187.0
SX1_k127_2011696_0 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 507.0
SX1_k127_2011696_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 442.0
SX1_k127_2011696_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 409.0
SX1_k127_2011696_3 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000003017 175.0
SX1_k127_2011696_4 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000004261 65.0
SX1_k127_2027241_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002355 255.0
SX1_k127_2027241_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000006649 228.0
SX1_k127_2027241_2 - - - - 0.000000000000000000000000000000000000000000000001119 179.0
SX1_k127_2027241_3 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000005829 68.0
SX1_k127_2027241_4 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000004458 63.0
SX1_k127_2027241_5 - - - - 0.000000000926 63.0
SX1_k127_2041645_0 Glycosyl hydrolase family 115 - - - 0.0 1261.0
SX1_k127_2052789_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 426.0
SX1_k127_2052789_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 331.0
SX1_k127_2052789_2 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 297.0
SX1_k127_2052789_3 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000007342 234.0
SX1_k127_2052789_4 adenyl ribonucleotide binding - - - 0.0000000000000000000000000000000000000000000003299 173.0
SX1_k127_2058391_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 574.0
SX1_k127_2058391_1 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 336.0
SX1_k127_2058391_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000005329 243.0
SX1_k127_2058391_3 PFAM peptidase M50 - - - 0.000000000000000000000000000000000802 136.0
SX1_k127_2058391_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000002938 94.0
SX1_k127_2061700_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.141e-252 790.0
SX1_k127_2061700_1 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 1.129e-248 777.0
SX1_k127_2061700_2 DEAD DEAH box helicase K06877 - - 1.633e-237 747.0
SX1_k127_2061700_3 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 3.623e-213 670.0
SX1_k127_2061700_4 DNA methylase K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 425.0
SX1_k127_2061700_5 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 368.0
SX1_k127_2061700_6 Acetyl xylan esterase (AXE1) K06889 - - 0.000000000000000000000000000000000003766 142.0
SX1_k127_2070199_0 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 467.0
SX1_k127_2070199_1 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004424 259.0
SX1_k127_2070199_2 - - - - 0.0000005732 51.0
SX1_k127_2070242_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 444.0
SX1_k127_2070242_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 348.0
SX1_k127_2070242_2 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001601 273.0
SX1_k127_2070242_3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000007522 234.0
SX1_k127_2070242_4 PFAM response regulator receiver - - - 0.00000000000000000000000000000371 129.0
SX1_k127_2098935_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.607e-231 726.0
SX1_k127_2098935_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.038e-216 679.0
SX1_k127_2098935_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 7.142e-202 638.0
SX1_k127_2098935_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 355.0
SX1_k127_2098935_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000001138 222.0
SX1_k127_2112381_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 522.0
SX1_k127_2112381_1 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 486.0
SX1_k127_2112381_2 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 299.0
SX1_k127_2112381_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 285.0
SX1_k127_2112381_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000006523 243.0
SX1_k127_2112381_5 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000006395 183.0
SX1_k127_2112381_6 PFAM phosphate transporter K03306 - - 0.000000000003663 67.0
SX1_k127_2132830_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.088e-304 946.0
SX1_k127_2132830_1 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 344.0
SX1_k127_2132830_2 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 328.0
SX1_k127_2132830_3 Protein of unknown function (DUF473) K09135 - - 0.0000000000000000000000000000000001554 137.0
SX1_k127_2132830_4 - - - - 0.000001416 52.0
SX1_k127_2142195_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 411.0
SX1_k127_2142195_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 357.0
SX1_k127_2171609_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 377.0
SX1_k127_2171609_1 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 297.0
SX1_k127_2171609_2 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000002257 138.0
SX1_k127_2171609_3 - - - - 0.000000000000000000000000001393 119.0
SX1_k127_2207122_0 Belongs to the glutamate synthase family - - - 2.466e-271 841.0
SX1_k127_2207122_1 PFAM glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 301.0
SX1_k127_2207122_2 PFAM glutamate synthase alpha subunit domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 284.0
SX1_k127_2209543_0 KH, type 1, domain K07041 - - 1.881e-308 951.0
SX1_k127_2209543_1 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 422.0
SX1_k127_2209543_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 310.0
SX1_k127_2209543_3 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000002315 199.0
SX1_k127_2209543_4 COG0589 Universal stress protein UspA and related nucleotide-binding - - - 0.000000000000000000000000000000000000000000002954 168.0
SX1_k127_2261659_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 518.0
SX1_k127_2261659_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 505.0
SX1_k127_2261659_2 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 375.0
SX1_k127_2261659_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 350.0
SX1_k127_2261659_4 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000002315 216.0
SX1_k127_2274142_0 SMART regulatory protein, Crp K07730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 385.0
SX1_k127_2274142_1 DEAD DEAH box helicase domain protein K03725 - - 0.00000000000000000000000000000000000000000000000000000000000006758 220.0
SX1_k127_2274142_2 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000001415 136.0
SX1_k127_2284909_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 3.14e-202 639.0
SX1_k127_2284909_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 9.95e-200 629.0
SX1_k127_2284909_2 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 532.0
SX1_k127_2284909_3 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.000000000000000001245 86.0
SX1_k127_2285072_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 501.0
SX1_k127_2285072_1 Belongs to the MCM family K10726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 345.0
SX1_k127_2285072_2 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000006444 147.0
SX1_k127_2285072_3 PFAM metallophosphoesterase K06953 - - 0.00005964 49.0
SX1_k127_2288825_0 SMART zinc finger, CDGSH-type domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 310.0
SX1_k127_2288825_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001474 306.0
SX1_k127_2288825_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004222 270.0
SX1_k127_2288825_3 PFAM RDD domain containing protein - - - 0.00000000000000000000000000000000000000000000000001941 183.0
SX1_k127_2288825_4 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000000000002105 173.0
SX1_k127_2288825_5 - K00960 - 2.7.7.6 0.000000000000000000000000000001669 120.0
SX1_k127_2288825_6 Chagasin family peptidase inhibitor I42 K14475 - - 0.00000000000000000000000289 108.0
SX1_k127_2288825_7 - - - - 0.00000000125 60.0
SX1_k127_2288825_8 metallopeptidase activity - - - 0.0000001358 66.0
SX1_k127_2292544_0 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.000000000000000000000000000000000000000000000000000000000000001182 221.0
SX1_k127_2292544_1 Domain of unknown function DUF87 - - - 0.000000000000000000000000000000001341 136.0
SX1_k127_2338187_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 554.0
SX1_k127_2338187_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 410.0
SX1_k127_2338187_2 - - - - 0.000004807 51.0
SX1_k127_2346438_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1442.0
SX1_k127_2346438_1 Uncharacterized protein conserved in archaea (DUF2114) - - - 6.74e-254 790.0
SX1_k127_2346438_10 - - - - 0.00000000000000000000000214 104.0
SX1_k127_2346438_2 PFAM Radical SAM domain protein K06937 - - 2.984e-244 761.0
SX1_k127_2346438_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 5.182e-202 634.0
SX1_k127_2346438_4 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 607.0
SX1_k127_2346438_5 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 406.0
SX1_k127_2346438_6 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 380.0
SX1_k127_2346438_7 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000001104 213.0
SX1_k127_2346438_8 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.0000000000000000000000000000000000000000000000000000576 189.0
SX1_k127_2346438_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000001999 177.0
SX1_k127_234877_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 565.0
SX1_k127_234877_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 472.0
SX1_k127_234877_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 368.0
SX1_k127_234877_3 Oxidoreductase K00177 - 1.2.7.3 0.00000000000000000002074 91.0
SX1_k127_234877_4 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000002314 57.0
SX1_k127_2358204_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 599.0
SX1_k127_2358204_2 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000000001687 173.0
SX1_k127_2358204_3 Helix-turn-helix domain protein K03627 - - 0.000000000000000000000000000000000000000000001133 170.0
SX1_k127_2378397_0 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004677 258.0
SX1_k127_2378397_1 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000001056 205.0
SX1_k127_2378397_2 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000004433 183.0
SX1_k127_2378397_3 Domain of unknown function DUF123 - - - 0.0000000000000000000000000000000000000000001323 163.0
SX1_k127_2378397_4 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.0000000000000000000000000000004619 127.0
SX1_k127_2398442_0 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 368.0
SX1_k127_2398442_1 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000000000000000000000000000005112 177.0
SX1_k127_2398442_2 COG1668 ABC-type Na efflux pump, permease component - - - 0.000000005419 57.0
SX1_k127_2407099_0 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 373.0
SX1_k127_2407099_1 DinB superfamily - - - 0.0000000001062 64.0
SX1_k127_2430396_0 4Fe-4S dicluster domain - - - 2.471e-241 749.0
SX1_k127_2430396_1 - - - - 0.00000000000000000000000006648 109.0
SX1_k127_2441237_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 489.0
SX1_k127_2441237_1 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 331.0
SX1_k127_2441237_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000208 171.0
SX1_k127_2441237_3 NADPH-dependent FMN reductase - - - 0.000000000000000000000000006288 111.0
SX1_k127_2447753_0 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 1.558e-316 977.0
SX1_k127_2450936_0 Domain of unknown function (DUF1724) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002922 237.0
SX1_k127_2450936_1 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000007393 121.0
SX1_k127_2450936_2 Protein of unknown function (DUF998) - - - 0.0000002055 54.0
SX1_k127_2458836_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 420.0
SX1_k127_2458836_1 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 347.0
SX1_k127_2458836_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 289.0
SX1_k127_2458836_3 Flavodoxin - - - 0.000000000000000000000000000000000000000001187 162.0
SX1_k127_2458836_4 Nitroreductase family - - - 0.000000000000000003852 86.0
SX1_k127_2458836_5 TIGRFAM PAS sensor protein - - - 0.000000000000009319 84.0
SX1_k127_2458836_6 Major facilitator superfamily K08166 - - 0.0001133 50.0
SX1_k127_2474335_0 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 428.0
SX1_k127_2474335_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000003131 133.0
SX1_k127_2493328_0 Protein of unknown function (DUF1116) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 415.0
SX1_k127_2499696_0 protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000004809 184.0
SX1_k127_2499696_1 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.0000000000000135 73.0
SX1_k127_2506052_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1152.0
SX1_k127_2506052_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.19e-231 724.0
SX1_k127_2506052_2 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 309.0
SX1_k127_2506052_3 PFAM thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002124 259.0
SX1_k127_2506052_4 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002875 256.0
SX1_k127_2506052_5 PFAM regulatory protein, ArsR K07721 - - 0.0000000000000000000000000000000000000000000000000000003722 199.0
SX1_k127_2506052_6 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000004451 143.0
SX1_k127_2506052_7 HEAT repeats - - - 0.000000000000000000000001025 109.0
SX1_k127_2506052_8 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000006162 85.0
SX1_k127_2506052_9 PBS lyase HEAT-like repeat - - - 0.0000000002063 67.0
SX1_k127_2512750_0 PFAM major facilitator superfamily MFS_1 K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 393.0
SX1_k127_2512750_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 340.0
SX1_k127_2512750_2 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 309.0
SX1_k127_2512750_3 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001112 281.0
SX1_k127_2512750_4 methyltransferase small K07579 - - 0.0000000000000000000000000000000000000000000000000000000000000006926 223.0
SX1_k127_2512750_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000004719 101.0
SX1_k127_2520485_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 607.0
SX1_k127_2520485_1 PFAM glutamine amidotransferase, class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 533.0
SX1_k127_2520485_2 PFAM Metallophosphoesterase - - - 0.0000000000000002518 84.0
SX1_k127_2521624_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 542.0
SX1_k127_2521624_1 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing K00123,K00367,K00372,K08356 - 1.17.1.9,1.20.2.1,1.20.9.1,1.7.7.2 0.0000000000000000000000000000000000000000000000000002943 185.0
SX1_k127_2521624_2 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.000000000000000000002795 94.0
SX1_k127_2521624_3 PBS lyase HEAT domain protein repeat-containing protein K22221 - - 0.0000931 46.0
SX1_k127_2558163_0 PFAM peptidase U32 K08303 - - 5.293e-202 660.0
SX1_k127_2558163_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 2.546e-200 635.0
SX1_k127_2558163_2 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000005921 179.0
SX1_k127_2572453_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 447.0
SX1_k127_2572453_1 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 367.0
SX1_k127_2572453_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 324.0
SX1_k127_2572453_3 Nitroreductase family - - - 0.00000000000000000000004124 101.0
SX1_k127_2572453_4 Nitroreductase family - - - 0.0000000000000000000003698 96.0
SX1_k127_2572453_5 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000008971 99.0
SX1_k127_2572453_6 Nitroreductase family - - - 0.000001792 50.0
SX1_k127_2592584_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 572.0
SX1_k127_2592584_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 520.0
SX1_k127_2592584_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008578 268.0
SX1_k127_2592584_3 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000001223 57.0
SX1_k127_2632221_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 390.0
SX1_k127_2632221_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 285.0
SX1_k127_2632221_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000002589 162.0
SX1_k127_2632221_3 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000057 53.0
SX1_k127_266624_0 sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 356.0
SX1_k127_266624_1 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005064 278.0
SX1_k127_2674973_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.216e-218 689.0
SX1_k127_2674973_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 534.0
SX1_k127_2674973_2 Membrane protein of unknown function DUF63 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 329.0
SX1_k127_2674973_3 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001222 273.0
SX1_k127_2674973_4 Belongs to the UPF0179 family K09730 - - 0.0000000000000000000000000000000000000000000000000000000007745 205.0
SX1_k127_2674973_5 Stage II sporulation protein M K06384 - - 0.000000000000000000000000000000000000974 146.0
SX1_k127_2674973_6 - - - - 0.00000000000000000000000000008366 118.0
SX1_k127_2674973_7 metal-binding protein - - - 0.0000000000000000000000003239 107.0
SX1_k127_2682125_0 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002675 255.0
SX1_k127_2712213_0 Heat shock 70 kDa protein K04043 - - 1.824e-240 751.0
SX1_k127_2712213_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000001308 192.0
SX1_k127_2712213_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000001601 158.0
SX1_k127_2729115_0 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 460.0
SX1_k127_2729115_1 PFAM TrkA-C domain K07228 - - 0.00000000000000000000000000000000000000000000000000000000002407 209.0
SX1_k127_27488_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 510.0
SX1_k127_27488_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 509.0
SX1_k127_27488_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 459.0
SX1_k127_27488_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000000000002065 155.0
SX1_k127_27488_4 Uncharacterised protein family UPF0058 - - - 0.00000000000000000000000000000000001327 137.0
SX1_k127_27488_5 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000000000000000002323 135.0
SX1_k127_27488_6 - - - - 0.00000000000000000000000006106 112.0
SX1_k127_27488_7 Belongs to the UPF0235 family K09131 - - 0.00000000005801 67.0
SX1_k127_2751269_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.948e-209 656.0
SX1_k127_2751269_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 571.0
SX1_k127_2751269_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000601 216.0
SX1_k127_2755720_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 470.0
SX1_k127_2755720_1 TIR domain - - - 0.000008192 54.0
SX1_k127_2757861_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006596 421.0
SX1_k127_2757861_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 417.0
SX1_k127_2757861_2 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 419.0
SX1_k127_2757861_3 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 304.0
SX1_k127_2757861_4 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000002696 128.0
SX1_k127_2758338_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 585.0
SX1_k127_2758338_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 434.0
SX1_k127_2758338_2 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000009962 198.0
SX1_k127_2764911_0 Small multi-drug export protein - - - 0.00000000000000000000000000000000000000001254 160.0
SX1_k127_2764911_1 Flavodoxin - - - 0.000000000000000000000000000000000744 136.0
SX1_k127_2764911_2 Uncharacterised protein family (UPF0153) K06940 - - 0.000009455 53.0
SX1_k127_278599_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 5.925e-229 726.0
SX1_k127_278599_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 2.085e-210 666.0
SX1_k127_278599_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 473.0
SX1_k127_278599_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 446.0
SX1_k127_278599_4 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 0.0000000000000000000000000004665 116.0
SX1_k127_2811778_0 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002436 251.0
SX1_k127_2811778_1 - - - - 0.000000000000000000000000000000000000000000000000000000002713 204.0
SX1_k127_2847307_0 Protein kinase, putative - - - 0.00000000000000002467 85.0
SX1_k127_2847307_1 TPR repeat-containing protein - - - 0.000006107 59.0
SX1_k127_2858355_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 569.0
SX1_k127_2858355_1 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 337.0
SX1_k127_2858355_2 Protein phosphatase 2C - - - 0.000000000000000000000000000000000000000000000000000000000000000000007449 245.0
SX1_k127_2858355_3 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000008114 111.0
SX1_k127_2858355_4 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000002372 81.0
SX1_k127_2858355_5 AAA ATPase central domain protein - - - 0.0000001813 63.0
SX1_k127_2866174_0 COG0863 DNA modification methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 400.0
SX1_k127_2866174_1 sugar phosphatases of the HAD superfamily K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008958 266.0
SX1_k127_2866174_2 - - - - 0.0000000000000000000000000000000001376 139.0
SX1_k127_2866174_3 RNase_H superfamily K07502 - - 0.000000000000005081 79.0
SX1_k127_2872521_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 324.0
SX1_k127_2872521_1 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 296.0
SX1_k127_2872521_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000000000000004021 135.0
SX1_k127_2872521_3 metallopeptidase activity - - - 0.00000000000000006612 86.0
SX1_k127_2872521_4 TfoX N-terminal domain - - - 0.0000000000000004526 81.0
SX1_k127_2874155_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 391.0
SX1_k127_2874155_1 N-4 methylation of cytosine K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 359.0
SX1_k127_2874155_2 Tetratricopeptide repeat - - - 0.000000000000000000000001174 110.0
SX1_k127_2898355_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 457.0
SX1_k127_2898355_1 Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 287.0
SX1_k127_2905694_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.625e-237 739.0
SX1_k127_2905694_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 488.0
SX1_k127_2905694_2 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 313.0
SX1_k127_2905694_3 COG1361 S-layer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 310.0
SX1_k127_2905694_4 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000008392 221.0
SX1_k127_2905694_5 Yip1 domain - - - 0.0000000000000000000000000000000000000000001583 167.0
SX1_k127_2905694_6 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.000000000000000000000001709 107.0
SX1_k127_2905694_7 Protein of unknown function (DUF2953) - - - 0.0000000008738 68.0
SX1_k127_2905694_8 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000007796 57.0
SX1_k127_2921492_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 7.301e-318 982.0
SX1_k127_2921492_1 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 382.0
SX1_k127_2929175_0 PFAM Linocin_M18 bacteriocin protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 321.0
SX1_k127_2929175_1 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003491 269.0
SX1_k127_2929175_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000005416 210.0
SX1_k127_2929175_3 Rubrerythrin - - - 0.000000000000000000000000000004424 123.0
SX1_k127_2929175_4 chorismate mutase K04093 - 5.4.99.5 0.0000000000000000000000528 102.0
SX1_k127_2929175_5 Peptidase M50 - - - 0.000000000000008306 76.0
SX1_k127_2929175_6 COG1413 FOG HEAT repeat - - - 0.00000001687 68.0
SX1_k127_2942917_0 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 517.0
SX1_k127_2942917_1 PFAM extracellular solute-binding protein family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000373 239.0
SX1_k127_2942917_2 Phage integrase family - - - 0.0001843 46.0
SX1_k127_2942917_3 aminotransferase class I and II K00812 - 2.6.1.1 0.0007427 42.0
SX1_k127_2947605_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 1.741e-229 720.0
SX1_k127_2947605_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 369.0
SX1_k127_2947605_10 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000002733 85.0
SX1_k127_2947605_2 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 306.0
SX1_k127_2947605_3 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 300.0
SX1_k127_2947605_4 Domain of unknown function (DUF1917) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 296.0
SX1_k127_2947605_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000006159 235.0
SX1_k127_2947605_6 Belongs to the UPF0218 family K09735 - - 0.000000000000000000000000000000000000000000000000000006793 194.0
SX1_k127_2947605_7 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000000000000000387 119.0
SX1_k127_2947605_8 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000000000000000007702 108.0
SX1_k127_2947605_9 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000002258 85.0
SX1_k127_2957134_0 SPFH Band 7 PHB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 367.0
SX1_k127_2957134_1 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000000000000000000001063 171.0
SX1_k127_2957134_2 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000007154 164.0
SX1_k127_2957134_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000001917 149.0
SX1_k127_2957134_4 COG1881 Phospholipid-binding protein K06910 - - 0.00000000000001171 79.0
SX1_k127_2983266_0 PFAM respiratory-chain NADH dehydrogenase, subunit 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 383.0
SX1_k127_2983266_1 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.0000000000000000000000000000000000000000000000000000007598 195.0
SX1_k127_2983266_2 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.0008668 42.0
SX1_k127_30282_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 372.0
SX1_k127_30282_1 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 300.0
SX1_k127_30282_2 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.00000000000000000000000491 104.0
SX1_k127_305001_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 7.519e-233 725.0
SX1_k127_305001_1 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 376.0
SX1_k127_305001_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000001333 201.0
SX1_k127_305001_3 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000001718 197.0
SX1_k127_3079578_0 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001067 278.0
SX1_k127_3079578_1 - - - - 0.00000000000000000000000000001822 119.0
SX1_k127_3079578_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000002859 78.0
SX1_k127_3087710_0 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 301.0
SX1_k127_3087710_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.000000000000000000000000000000000000000000000000000000000006967 209.0
SX1_k127_3087710_2 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.00000000000000000000000000000000000000000902 158.0
SX1_k127_3134092_0 Belongs to the RtcB family K14415 - 6.5.1.3 2.127e-219 689.0
SX1_k127_3134092_1 Protein-export membrane protein SecD K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 527.0
SX1_k127_3134092_2 Radical SAM ThiC family K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 489.0
SX1_k127_3134092_3 Involved in protein export K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 346.0
SX1_k127_3134092_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000001841 221.0
SX1_k127_3134092_5 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000000000000000575 143.0
SX1_k127_3134092_6 Protein of unknown function (DUF2551) - - - 0.00000000000000000000000000000000001201 141.0
SX1_k127_3134092_7 - - - - 0.000000000000000004031 88.0
SX1_k127_3184049_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 325.0
SX1_k127_3184049_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000002625 260.0
SX1_k127_3184049_2 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.0000000000000000000000000000000000000000000000000000003722 199.0
SX1_k127_3184049_3 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.0000000002805 62.0
SX1_k127_3187647_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 352.0
SX1_k127_3187647_2 Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002798 239.0
SX1_k127_3202858_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 407.0
SX1_k127_3202858_1 COG NOG14600 non supervised orthologous group - - - 0.00000000009301 63.0
SX1_k127_3204165_0 PFAM GTP-binding protein HSR1-related K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 366.0
SX1_k127_3204165_1 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.000000000000000000000000000000000000000000000000003771 183.0
SX1_k127_3204165_2 Zn-ribbon containing protein K07163 - - 0.000000000000000000000000000000000000000000000002308 176.0
SX1_k127_3256097_0 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 287.0
SX1_k127_3256097_1 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000009428 135.0
SX1_k127_3256097_2 PFAM HhH-GPD family protein K07457 - - 0.00000000000000000000000000000001854 130.0
SX1_k127_3256097_3 Protein-export membrane protein SecD K03072 - - 0.0000000000000017 76.0
SX1_k127_3294105_0 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 2.416e-204 646.0
SX1_k127_3350280_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 6.727e-245 761.0
SX1_k127_3350280_1 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 377.0
SX1_k127_3350280_2 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006341 282.0
SX1_k127_3350280_3 Thioesterase superfamily K02614 - - 0.000000000000000000000000000000000000000000000003527 177.0
SX1_k127_3350280_4 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000009513 175.0
SX1_k127_3350280_5 - - - - 0.00001004 51.0
SX1_k127_3421575_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 557.0
SX1_k127_3421575_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000001027 215.0
SX1_k127_3421575_2 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.00000000000004605 73.0
SX1_k127_3426657_0 AAA-like domain K06915 - - 5.853e-198 627.0
SX1_k127_3426657_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 298.0
SX1_k127_3434909_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003954 261.0
SX1_k127_3434909_1 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007804 251.0
SX1_k127_3434909_2 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000001809 63.0
SX1_k127_3457044_0 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000000004768 198.0
SX1_k127_3457044_1 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000007591 163.0
SX1_k127_3457044_2 - - - - 0.0000000000000002681 87.0
SX1_k127_3457753_0 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 555.0
SX1_k127_3457753_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000004551 243.0
SX1_k127_3457753_2 Putative small multi-drug export protein - - - 0.0000000000000000000000000000000000000000127 159.0
SX1_k127_3467414_0 PFAM zinc iron permease K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 321.0
SX1_k127_3467414_1 UV-endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006142 255.0
SX1_k127_3468495_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 336.0
SX1_k127_3468495_1 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000005132 223.0
SX1_k127_3468495_2 Cobalamin synthesis G C-terminus K02189 - 3.7.1.12 0.000007901 55.0
SX1_k127_3473517_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 9.983e-207 662.0
SX1_k127_3473517_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000007358 157.0
SX1_k127_3473517_2 DNA polymerase activity K02319 - 2.7.7.7 0.000000000000000001484 92.0
SX1_k127_3473517_3 - - - - 0.0000005297 56.0
SX1_k127_3479957_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 335.0
SX1_k127_3479957_1 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.0000000001848 63.0
SX1_k127_3499763_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 535.0
SX1_k127_3499763_1 Small multi-drug export protein - - - 0.000000000000000000000000000000001532 137.0
SX1_k127_3508300_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 466.0
SX1_k127_3508300_1 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.000000000000006193 77.0
SX1_k127_3508300_2 - - - - 0.00000000000002518 75.0
SX1_k127_3516937_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 3.772e-245 763.0
SX1_k127_3516937_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 558.0
SX1_k127_3516937_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000002377 230.0
SX1_k127_3516937_11 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000002259 216.0
SX1_k127_3516937_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000004732 208.0
SX1_k127_3516937_13 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000008338 193.0
SX1_k127_3516937_14 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000004092 191.0
SX1_k127_3516937_15 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.0000000000000000000000000000000000000000000006401 168.0
SX1_k127_3516937_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000000000000000415 128.0
SX1_k127_3516937_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000000002218 91.0
SX1_k127_3516937_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 449.0
SX1_k127_3516937_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 456.0
SX1_k127_3516937_4 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 409.0
SX1_k127_3516937_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 387.0
SX1_k127_3516937_6 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 369.0
SX1_k127_3516937_7 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 366.0
SX1_k127_3516937_8 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 337.0
SX1_k127_3516937_9 Located on the platform of the 30S subunit K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000005452 235.0
SX1_k127_3542520_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 4.03e-235 736.0
SX1_k127_3542520_1 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.00000000000000000000000000000000000000000000000009803 178.0
SX1_k127_3542520_2 - - - - 0.000000000000168 71.0
SX1_k127_3582723_0 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 434.0
SX1_k127_3582723_1 PFAM ABC transporter related K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 341.0
SX1_k127_3582723_10 PFAM Radical SAM domain protein - - - 0.0000000000001675 72.0
SX1_k127_3582723_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 341.0
SX1_k127_3582723_3 - - - - 0.0000000000000000000000000000000000000000000000000001003 191.0
SX1_k127_3582723_4 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000008837 188.0
SX1_k127_3582723_5 - K00960 - 2.7.7.6 0.00000000000000000000000000000009006 125.0
SX1_k127_3582723_6 Protein of unknown function (DUF2769) - - - 0.0000000000000000000000001887 108.0
SX1_k127_3582723_7 - - - - 0.0000000000000000000001346 105.0
SX1_k127_3582723_8 PFAM peptidase U32 K08303 - - 0.000000000000000000005201 95.0
SX1_k127_3582723_9 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000002847 94.0
SX1_k127_3650663_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 314.0
SX1_k127_3650663_1 KH, type 1, domain K07041 - - 0.0000000000000000000000000000000007325 130.0
SX1_k127_3677323_0 Transport of potassium into the cell K03549 - - 3.691e-261 817.0
SX1_k127_3677323_1 TGS domain protein K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 560.0
SX1_k127_3677323_2 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 392.0
SX1_k127_3677323_3 Pyruvate kinase, alpha/beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006325 270.0
SX1_k127_3677323_4 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000000000000007122 197.0
SX1_k127_3677323_5 acetyltransferase - - - 0.0000000000000000000000000000000000000002755 155.0
SX1_k127_3677323_6 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.00000000000000000004049 99.0
SX1_k127_3683815_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 6.406e-258 810.0
SX1_k127_3683815_1 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 613.0
SX1_k127_3683815_10 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001424 260.0
SX1_k127_3683815_11 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000003464 239.0
SX1_k127_3683815_12 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000002854 224.0
SX1_k127_3683815_13 Belongs to the UPF0212 family K09731 - - 0.000000000000000000000000000000000000000000000000001291 184.0
SX1_k127_3683815_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000000000000000000000000000000000007399 175.0
SX1_k127_3683815_15 Family of unknown function (DUF5350) - - - 0.000000000000000000000000022 114.0
SX1_k127_3683815_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 539.0
SX1_k127_3683815_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 420.0
SX1_k127_3683815_4 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 364.0
SX1_k127_3683815_5 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 370.0
SX1_k127_3683815_6 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 354.0
SX1_k127_3683815_7 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 350.0
SX1_k127_3683815_8 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 344.0
SX1_k127_3683815_9 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002303 265.0
SX1_k127_3699403_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 575.0
SX1_k127_3699403_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 502.0
SX1_k127_3699403_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000007658 160.0
SX1_k127_3699403_3 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.000000000000000000000433 98.0
SX1_k127_3715252_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006021 244.0
SX1_k127_3715252_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000003361 77.0
SX1_k127_3715252_2 Possibly the antitoxin component of a - - - 0.00001025 51.0
SX1_k127_3719758_0 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 516.0
SX1_k127_3719758_1 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000000000000000002387 156.0
SX1_k127_3719758_2 - - - - 0.0000000000000000000000000000000054 133.0
SX1_k127_3719758_3 4Fe-4S dicluster domain - - - 0.00000000000000000003913 91.0
SX1_k127_3719758_4 Oxidoreductase activity. It is involved in the biological process described with metabolic process K11153 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.1.1.300 0.00000004774 55.0
SX1_k127_3734040_0 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 376.0
SX1_k127_3734040_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000006123 233.0
SX1_k127_3734040_2 PHP domain protein - - - 0.000000000000000000000000000000000000000005583 158.0
SX1_k127_3734040_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000000000000000000000000000005124 125.0
SX1_k127_3734040_4 Protease prsW family - - - 0.0000441 51.0
SX1_k127_3749571_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 378.0
SX1_k127_3749571_1 Amino acid ABC transporter substrate-binding protein, PAAT family K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 347.0
SX1_k127_3749571_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 335.0
SX1_k127_3749571_3 amino acid ABC transporter K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 312.0
SX1_k127_3749571_4 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 306.0
SX1_k127_3749571_5 Amino acid ABC transporter substrate-binding protein, PAAT family K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 306.0
SX1_k127_3749571_6 archaeosine synthase activity K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008753 282.0
SX1_k127_3758114_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 1.231e-272 856.0
SX1_k127_3758114_1 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000002063 198.0
SX1_k127_3758114_2 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000000000000000000000004575 140.0
SX1_k127_3762030_0 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 2.873e-260 822.0
SX1_k127_3762030_1 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 415.0
SX1_k127_3778210_0 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 3.331e-223 702.0
SX1_k127_3778210_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 469.0
SX1_k127_3778210_2 binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000000000000000003637 170.0
SX1_k127_3778210_3 protein conserved in archaea K09723 - - 0.000000000000000000000000000000000003687 144.0
SX1_k127_3778210_4 PFAM Ribosomal protein S27E K02978 - - 0.0000000000000000000000002159 106.0
SX1_k127_3778210_5 Translation initiation factor 2 alpha subunit K03237 - - 0.0000000000000000002708 87.0
SX1_k127_3790972_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 599.0
SX1_k127_3790972_1 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 585.0
SX1_k127_3790972_2 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 354.0
SX1_k127_3790972_3 TIGRFAM formate dehydrogenase family accessory protein FdhD K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 285.0
SX1_k127_3790972_4 Domain of unknown function (DUF1890) - - - 0.00000000000000000000000000000000000000000000000006302 183.0
SX1_k127_3790972_5 Domain of unknown function (DUF1894) - - - 0.000000000000000000000000000005829 121.0
SX1_k127_3790972_6 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000002641 103.0
SX1_k127_3790972_7 Transcriptional regulator K07108 - - 0.0000000000000000000001546 101.0
SX1_k127_3803715_0 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 481.0
SX1_k127_3803715_1 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000002008 269.0
SX1_k127_3803715_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000000000000003686 227.0
SX1_k127_3803715_3 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.00000000000000000000000000000000000000000000000894 174.0
SX1_k127_3803715_4 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000003835 156.0
SX1_k127_3803715_5 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000009731 128.0
SX1_k127_3803715_6 Protein of unknown function (DUF1614) - - - 0.0004395 45.0
SX1_k127_3807098_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 557.0
SX1_k127_3807098_1 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 290.0
SX1_k127_3807098_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003356 276.0
SX1_k127_3807098_3 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.000000000000000000002627 95.0
SX1_k127_3825070_0 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000000000006148 237.0
SX1_k127_3825070_1 COG1361 S-layer domain - - - 0.00000000000000000000000000000000000000005088 156.0
SX1_k127_3825070_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000002783 134.0
SX1_k127_3825070_3 Psort location Cytoplasmic, score 8.87 - - - 0.000000001856 61.0
SX1_k127_3826657_0 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 297.0
SX1_k127_3826657_1 PFAM Histone deacetylase - - - 0.00000000000000000000000000000003513 130.0
SX1_k127_3829045_0 - - - - 0.0000000002601 72.0
SX1_k127_3832105_0 - K14093 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001177 247.0
SX1_k127_3832105_1 PFAM Cation K03498 - - 0.00000000000000000000000000000000000000000000000000001491 194.0
SX1_k127_3832105_2 Predicted membrane protein (DUF2107) K14096 - - 0.0000000000000000000006199 99.0
SX1_k127_3832105_3 Predicted membrane protein (DUF2109) K14094 - - 0.000000000000000002048 91.0
SX1_k127_3832105_4 Predicted membrane protein (DUF2108) K14095 - - 0.00000000000006116 76.0
SX1_k127_3835839_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 2.243e-317 984.0
SX1_k127_3840501_0 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 552.0
SX1_k127_3840501_1 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 499.0
SX1_k127_3840501_2 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000000000000000000000000000003304 209.0
SX1_k127_3840501_3 DGC domain - - - 0.00000000000000000000000003149 112.0
SX1_k127_3843206_0 Domain of unknown function DUF87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 375.0
SX1_k127_3843206_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 368.0
SX1_k127_3843206_2 FHA domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001242 274.0
SX1_k127_3843206_3 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000213 192.0
SX1_k127_3843206_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000001057 137.0
SX1_k127_3851019_0 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 601.0
SX1_k127_3851019_1 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 460.0
SX1_k127_3851019_2 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 355.0
SX1_k127_3851019_3 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000001638 229.0
SX1_k127_3851019_4 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000000000000000003246 226.0
SX1_k127_3851019_5 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000003215 220.0
SX1_k127_3851019_6 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000000000000000000001092 144.0
SX1_k127_3851019_7 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000006406 138.0
SX1_k127_3851019_8 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000001481 60.0
SX1_k127_3857482_0 E1-E2 ATPase K17686 - 3.6.3.54 5.879e-310 965.0
SX1_k127_3857482_1 - - - - 0.00000000000000000000002723 100.0
SX1_k127_3857482_2 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000003342 93.0
SX1_k127_3863117_0 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 436.0
SX1_k127_3863117_1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 410.0
SX1_k127_3863117_2 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003995 267.0
SX1_k127_3863117_3 hydrolase K04794 - 3.1.1.29 0.000000000000000000000000000000000000000000000009828 178.0
SX1_k127_3863117_4 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000008626 102.0
SX1_k127_3863117_5 PDGLE domain K02009 - - 0.000000000000000000002277 106.0
SX1_k127_3909329_0 SMART Elongator protein 3 MiaB NifB - - - 3.793e-260 814.0
SX1_k127_3909329_1 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003642 265.0
SX1_k127_3909329_2 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000001341 141.0
SX1_k127_3909329_3 nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000000000002218 110.0
SX1_k127_3909329_4 transcriptional regulators K03724 - - 0.00000000000000000004646 91.0
SX1_k127_3920282_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 2.51e-262 820.0
SX1_k127_3920282_1 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 607.0
SX1_k127_3920282_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 297.0
SX1_k127_3920282_3 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 294.0
SX1_k127_3920282_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000003273 215.0
SX1_k127_3920282_5 DEAD DEAH box helicase domain protein K10896 - - 0.0000000000000000000000000000000000000000005865 160.0
SX1_k127_3920282_6 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.00000000000000000004767 91.0
SX1_k127_3926874_0 Protein of unknown function (DUF521) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 378.0
SX1_k127_3926874_1 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000005793 117.0
SX1_k127_3934196_0 DEAD DEAH box helicase domain protein K03725 - - 3.316e-213 670.0
SX1_k127_3954880_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 321.0
SX1_k127_3954880_1 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 291.0
SX1_k127_3954880_2 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000279 269.0
SX1_k127_3954880_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000007261 108.0
SX1_k127_3979495_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 510.0
SX1_k127_3979495_1 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 430.0
SX1_k127_3979495_2 Domain of unknown function (DUF1743) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 417.0
SX1_k127_3979495_3 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 350.0
SX1_k127_3979495_4 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003533 294.0
SX1_k127_3979495_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11260 - - 0.0000000000000000000000000000000000000000009233 160.0
SX1_k127_3979495_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.00000000000000000000000004343 108.0
SX1_k127_3979495_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.000000000001005 69.0
SX1_k127_3980726_0 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 391.0
SX1_k127_3980726_1 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000001721 185.0
SX1_k127_3987519_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 7.225e-229 721.0
SX1_k127_3987519_1 tRNAHis guanylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 304.0
SX1_k127_3990859_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 600.0
SX1_k127_3990859_1 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000000000000000000000000000004596 175.0
SX1_k127_40140_0 PFAM SufBD protein K07033 - - 4.041e-195 612.0
SX1_k127_40140_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000002259 258.0
SX1_k127_4046813_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.024e-245 765.0
SX1_k127_4046813_1 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000008989 181.0
SX1_k127_4094763_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1306.0
SX1_k127_4094763_1 PFAM PilT protein domain protein K06865 - - 2.133e-279 870.0
SX1_k127_4094763_10 - - - - 0.000000000757 68.0
SX1_k127_4094763_2 TIGRFAM cell division ATPase MinD K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 385.0
SX1_k127_4094763_3 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 331.0
SX1_k127_4094763_4 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000152 235.0
SX1_k127_4094763_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000007837 188.0
SX1_k127_4094763_6 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000021 178.0
SX1_k127_4094763_7 Roadblock LC7 K07131 - - 0.000000000000000000000000000000000000000000001247 167.0
SX1_k127_4094763_8 - - - - 0.000000000000000000000000000000000000000000905 164.0
SX1_k127_4094763_9 - - - - 0.0000000000000000000000003371 108.0
SX1_k127_4099168_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 4.661e-205 644.0
SX1_k127_4099168_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000003628 186.0
SX1_k127_4099168_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000005729 160.0
SX1_k127_4099168_3 - - - - 0.0000000000000000008303 93.0
SX1_k127_4112674_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 449.0
SX1_k127_4112674_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 442.0
SX1_k127_4112674_2 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 429.0
SX1_k127_4112674_3 Cysteine-rich small domain K08260 - 3.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 392.0
SX1_k127_4112674_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000006737 221.0
SX1_k127_4112674_5 Anaerobic ribonucleoside-triphosphate reductase - - - 0.0000000000000000000000000000000000000000000000000000000023 201.0
SX1_k127_4112674_6 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000001145 106.0
SX1_k127_4131535_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 4.151e-255 793.0
SX1_k127_4131535_1 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 353.0
SX1_k127_415782_0 phosphohydrolase (DHH superfamily) K07097 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 351.0
SX1_k127_415782_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001783 271.0
SX1_k127_415782_2 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000308 112.0
SX1_k127_4180623_0 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 521.0
SX1_k127_4180623_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 293.0
SX1_k127_4180623_2 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 286.0
SX1_k127_4180623_3 Thioredoxin - - - 0.0000000000000000000000000000000000000000000003453 170.0
SX1_k127_4209928_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 369.0
SX1_k127_4209928_1 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 289.0
SX1_k127_4225794_0 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 443.0
SX1_k127_4225794_1 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 319.0
SX1_k127_4225794_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 314.0
SX1_k127_4225794_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000008694 250.0
SX1_k127_4225794_4 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000004365 214.0
SX1_k127_4225794_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000001022 181.0
SX1_k127_4228754_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009375 606.0
SX1_k127_4228754_1 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 417.0
SX1_k127_4228754_2 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 400.0
SX1_k127_4228754_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 343.0
SX1_k127_4228754_4 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000004491 229.0
SX1_k127_4228754_5 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.00000000000000000000000000000000000000000000001332 176.0
SX1_k127_4228754_6 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.000000000000000005509 84.0
SX1_k127_4245765_0 AMP-binding enzyme - - - 5.15e-221 692.0
SX1_k127_4245765_1 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000212 185.0
SX1_k127_4245765_2 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000000000000000007043 158.0
SX1_k127_4245765_3 PFAM Radical SAM domain protein - - - 0.0000000000000003099 80.0
SX1_k127_4245765_4 PFAM Radical SAM domain protein - - - 0.000004933 49.0
SX1_k127_4270142_0 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 348.0
SX1_k127_4270142_1 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000133 157.0
SX1_k127_4270142_2 nucleoside 2-deoxyribosyltransferase - - - 0.0000000000000000000000000000000005425 142.0
SX1_k127_4283718_0 PFAM ribonuclease II K01147 - 3.1.13.1 1.52e-200 635.0
SX1_k127_4283718_1 PFAM Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000009948 184.0
SX1_k127_4283718_2 Adenosine specific kinase K09129 - - 0.00000000000000000000001657 100.0
SX1_k127_4283718_3 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000001983 91.0
SX1_k127_429388_0 signal transduction protein with CBS domains K07744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 401.0
SX1_k127_429388_1 TIGRFAM small GTP-binding protein K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 392.0
SX1_k127_429388_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 370.0
SX1_k127_429388_3 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 323.0
SX1_k127_429388_4 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000001648 205.0
SX1_k127_429388_5 PFAM PRC-barrel domain - - - 0.0000000000000000000000000000000003163 132.0
SX1_k127_429388_6 - - - - 0.000000000000000000000000000000001341 136.0
SX1_k127_4299509_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.116e-229 721.0
SX1_k127_4299509_1 - - - - 0.00000000000000000002925 91.0
SX1_k127_4299509_2 - - - - 0.0000000001177 62.0
SX1_k127_4330122_0 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 329.0
SX1_k127_4330122_1 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000496 269.0
SX1_k127_4330122_2 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.000000000000000000000000000000000000000000000000000000000000000000003708 243.0
SX1_k127_4330122_3 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000000000000000005377 202.0
SX1_k127_4330122_4 Belongs to the PDCD5 family K06875 - - 0.0000000000000000000000000000000000002331 145.0
SX1_k127_4330122_5 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000000000000000000000000001308 136.0
SX1_k127_4330122_6 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000000000000000001979 114.0
SX1_k127_4330122_7 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000001839 96.0
SX1_k127_4330122_8 CRS1_YhbY K07574 - - 0.00000000000000000001659 93.0
SX1_k127_4330122_9 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002579 91.0
SX1_k127_4340592_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 498.0
SX1_k127_4340592_1 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 481.0
SX1_k127_4340592_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 314.0
SX1_k127_4340592_3 methanogen marker protein 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 301.0
SX1_k127_4340592_4 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000806 251.0
SX1_k127_4340592_5 PFAM peptidase zinc-dependent K06974 - - 0.00000000000000000000000000000000000000000000000000000001056 201.0
SX1_k127_4340592_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000003164 151.0
SX1_k127_4340592_7 Belongs to the UPF0146 family K09713 - - 0.000000000000000000000000000000000000001506 156.0
SX1_k127_4340592_8 transcription factor (CBF NF-Y) - - - 0.00000000000000000000000000697 113.0
SX1_k127_4349664_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.321e-250 782.0
SX1_k127_4349664_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 496.0
SX1_k127_4349664_2 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000003231 165.0
SX1_k127_4356397_0 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 478.0
SX1_k127_4356397_1 TIGRFAM UbiD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 403.0
SX1_k127_4356397_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000001874 248.0
SX1_k127_4356397_3 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000007196 217.0
SX1_k127_4356397_4 PBS lyase HEAT-like repeat - - - 0.00000000000000001203 90.0
SX1_k127_4417652_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 348.0
SX1_k127_4417652_1 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 342.0
SX1_k127_4417652_2 Belongs to the dCTP deaminase family K01494,K09887 - 3.5.4.13,3.5.4.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 300.0
SX1_k127_4417652_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000002697 224.0
SX1_k127_4418736_0 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 563.0
SX1_k127_4418736_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 505.0
SX1_k127_4418736_10 PFAM sigma-70 region 4 domain protein K09714 - - 0.0000000000000000000000000000000000000000000000002657 179.0
SX1_k127_4418736_11 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.000000000000000000000008128 105.0
SX1_k127_4418736_12 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000000000000000000009563 104.0
SX1_k127_4418736_13 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000002527 91.0
SX1_k127_4418736_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000004081 78.0
SX1_k127_4418736_2 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 469.0
SX1_k127_4418736_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 357.0
SX1_k127_4418736_4 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 354.0
SX1_k127_4418736_5 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 351.0
SX1_k127_4418736_6 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 344.0
SX1_k127_4418736_7 Involved in cell shape control K22222 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001988 280.0
SX1_k127_4418736_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000000000000002264 213.0
SX1_k127_4418736_9 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000000003234 204.0
SX1_k127_4449966_0 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000002884 209.0
SX1_k127_4449966_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000000000000000005104 207.0
SX1_k127_4449966_2 choline dehydrogenase activity - - - 0.0000000000000000000000000000000000000002763 157.0
SX1_k127_4449966_3 PFAM Glucose-methanol-choline oxidoreductase, N-terminal - - - 0.000000000000000000000000002545 117.0
SX1_k127_4449966_4 signal transduction protein with CBS domains - - - 0.00000000000000000000000002104 120.0
SX1_k127_4449966_5 CBS domain - - - 0.000000000000003607 86.0
SX1_k127_445639_0 PFAM CBS domain - - - 2.174e-211 664.0
SX1_k127_445639_1 ATP-grasp domain K06913 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 421.0
SX1_k127_445639_2 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 292.0
SX1_k127_445639_3 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000004968 238.0
SX1_k127_445639_4 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000000000000000000000000000000003629 175.0
SX1_k127_445639_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000001598 173.0
SX1_k127_445639_6 - - - - 0.000000000000000000000000004076 116.0
SX1_k127_445639_7 - - - - 0.00000000000002255 79.0
SX1_k127_446679_0 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 391.0
SX1_k127_446679_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 308.0
SX1_k127_446679_2 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000008313 190.0
SX1_k127_446679_3 Protein of unknown function (DUF357) K09728 - - 0.000000000000000000000000000000000117 139.0
SX1_k127_446679_4 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000007656 96.0
SX1_k127_4497409_0 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 378.0
SX1_k127_4497409_1 PFAM BioY protein K03523 - - 0.00000000000000000000000000000000000000000000000002303 185.0
SX1_k127_4497409_2 PFAM ABC transporter K16786 - - 0.0000000000000000000000000000000000000000004582 162.0
SX1_k127_4497409_3 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.0000000000308 63.0
SX1_k127_4510189_0 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 532.0
SX1_k127_4510189_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000002048 249.0
SX1_k127_4510189_2 Pro-kumamolisin, activation domain K08677 - - 0.000000000002798 81.0
SX1_k127_4515975_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 432.0
SX1_k127_4515975_1 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003736 256.0
SX1_k127_4515975_2 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.000000000000000000000000000000000000000000000000000000001152 203.0
SX1_k127_4515975_3 PFAM NiFe -hydrogenase-3-type complex Eha, EhaM K14104 - - 0.000000000000000000001964 99.0
SX1_k127_4517487_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 6.976e-240 752.0
SX1_k127_4517487_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 3.849e-232 728.0
SX1_k127_4517487_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 364.0
SX1_k127_4517487_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 321.0
SX1_k127_4517487_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000003456 263.0
SX1_k127_4517487_5 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000001072 235.0
SX1_k127_4517487_6 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000000000000000000000005326 164.0
SX1_k127_4517487_7 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.00004611 49.0
SX1_k127_454380_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.712e-215 676.0
SX1_k127_454380_1 PFAM PUA domain containing protein K07575 - - 0.0000000000000000000000000000000000000000000000000000000007969 206.0
SX1_k127_454380_2 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000000001165 168.0
SX1_k127_454380_3 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000006771 164.0
SX1_k127_454380_4 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000000000000000004442 132.0
SX1_k127_454380_5 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000007091 134.0
SX1_k127_454380_6 binds to the 23S rRNA K02922 - - 0.00000000000000000000000000009666 115.0
SX1_k127_454380_7 Pfam:DUF552 K09152 - - 0.00000000000009588 72.0
SX1_k127_454380_8 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000001728 54.0
SX1_k127_454380_9 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00002259 49.0
SX1_k127_4552429_0 Uncharacterized protein conserved in archaea (DUF2121) - - - 0.0000000000000000000000000000000000000000000000000007237 190.0
SX1_k127_4552429_1 EamA-like transporter family - - - 0.0000000000000000000000000000001377 130.0
SX1_k127_4552429_2 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000001214 101.0
SX1_k127_4552429_3 PFAM flavin reductase domain protein FMN-binding - - - 0.00000000000000000007179 91.0
SX1_k127_4552429_4 DMT(Drug metabolite transporter) superfamily permease - - - 0.000002317 53.0
SX1_k127_4552597_0 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 366.0
SX1_k127_4552597_1 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 316.0
SX1_k127_4552597_2 Tetratricopeptide repeat - - - 0.00000000000000000003053 99.0
SX1_k127_4567772_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 357.0
SX1_k127_4567772_1 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 298.0
SX1_k127_4567772_2 PFAM Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000001414 169.0
SX1_k127_4567772_3 PP-loop domain protein K06864 - - 0.0000000000000000005606 88.0
SX1_k127_4581425_0 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 316.0
SX1_k127_4581425_1 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000000000000000000000000000000004623 224.0
SX1_k127_4581425_2 - - - - 0.00000005289 55.0
SX1_k127_4581425_3 - - - - 0.00001457 51.0
SX1_k127_458652_0 DEAD DEAH box helicase domain protein K10896 - - 9.102e-260 815.0
SX1_k127_458652_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 508.0
SX1_k127_458652_2 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000007791 254.0
SX1_k127_458652_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000741 208.0
SX1_k127_458652_4 TfuA-like protein - - - 0.0000000000000000000000000000000000000000000001654 176.0
SX1_k127_458652_5 Belongs to the UPF0147 family K09721 - - 0.000000000000000000000000000000000001086 139.0
SX1_k127_458652_6 PFAM molybdopterin biosynthesis MoaE K03635,K21142 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.0000000000000000000000000000001763 127.0
SX1_k127_458652_7 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.0000000000000000002923 92.0
SX1_k127_458652_8 ThiS family K03636 - - 0.0000007465 57.0
SX1_k127_4601477_0 AAA domain - - - 9.483e-235 748.0
SX1_k127_4682218_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007543 265.0
SX1_k127_4682218_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000004174 171.0
SX1_k127_4682218_2 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000000001696 154.0
SX1_k127_4682218_3 - - - - 0.0000000000000000000000000014 116.0
SX1_k127_4692532_0 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 409.0
SX1_k127_4692532_1 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 313.0
SX1_k127_4692532_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000002597 199.0
SX1_k127_4732086_0 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 364.0
SX1_k127_4732086_1 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004152 269.0
SX1_k127_4732086_2 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.00000000000000000000000000000000000000000000000000000009268 200.0
SX1_k127_4737909_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 3.359e-210 663.0
SX1_k127_4737909_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 519.0
SX1_k127_4737909_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004786 259.0
SX1_k127_4737909_3 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000000000000000000000000000000000000000000000000000009749 261.0
SX1_k127_4742958_0 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 612.0
SX1_k127_4742958_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007381 262.0
SX1_k127_4742958_2 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.0000000000000000000000000000000000000000000000000000000000000006946 223.0
SX1_k127_4742958_3 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.000000000000000000000000000000000005087 140.0
SX1_k127_4742958_4 Multiple resistance and pH regulation protein F K05570 - - 0.00000000000000000000146 96.0
SX1_k127_4743780_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.259e-215 674.0
SX1_k127_4743780_1 Required for chromosome condensation and partitioning K03529 - - 2.928e-201 649.0
SX1_k127_4743780_10 - - - - 0.0000000000000001041 86.0
SX1_k127_4743780_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 409.0
SX1_k127_4743780_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 336.0
SX1_k127_4743780_4 TIGRFAM F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 328.0
SX1_k127_4743780_5 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 258.0
SX1_k127_4743780_6 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000006882 243.0
SX1_k127_4743780_7 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000009645 203.0
SX1_k127_4743780_8 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000000000000004283 173.0
SX1_k127_4743780_9 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000001103 159.0
SX1_k127_4745492_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.98.1 2.915e-251 781.0
SX1_k127_4745492_1 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 502.0
SX1_k127_4745492_2 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 454.0
SX1_k127_4745492_3 coenzyme F420-reducing hydrogenase, delta subunit K00442 - - 0.000000000000000000000000000000000000000000000000000005693 196.0
SX1_k127_4745492_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000001159 168.0
SX1_k127_4745492_5 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000002219 76.0
SX1_k127_4745492_6 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000008193 71.0
SX1_k127_4750831_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 534.0
SX1_k127_475597_0 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000003022 235.0
SX1_k127_475597_1 Flavodoxin domain - - - 0.0000000000000000000000000000000000000000000001262 172.0
SX1_k127_475597_2 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000004694 152.0
SX1_k127_478187_0 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 346.0
SX1_k127_478187_1 permease K03299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 323.0
SX1_k127_478187_2 - - - - 0.000000000000000000000000000000004478 132.0
SX1_k127_4788506_0 ATP-grasp domain K06914 - 6.3.4.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 379.0
SX1_k127_4788506_1 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 338.0
SX1_k127_4788506_2 - - - - 0.0000000000000000000000000000000000000000001375 166.0
SX1_k127_4788506_3 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000000000000000001522 132.0
SX1_k127_4809648_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.27e-322 992.0
SX1_k127_4809648_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 325.0
SX1_k127_4809648_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000001398 100.0
SX1_k127_4809648_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000001469 70.0
SX1_k127_4835290_0 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 349.0
SX1_k127_4835290_1 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000000000000000000001119 179.0
SX1_k127_4835290_2 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000002195 132.0
SX1_k127_4835290_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000004443 119.0
SX1_k127_483750_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 607.0
SX1_k127_483750_1 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 524.0
SX1_k127_483750_2 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000001937 151.0
SX1_k127_483750_3 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000000000000000001603 139.0
SX1_k127_483750_4 - - - - 0.00000000002306 65.0
SX1_k127_4855765_0 Belongs to the MCM family K10726 - - 1.215e-211 664.0
SX1_k127_4855765_1 PFAM TatD-related deoxyribonuclease K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 377.0
SX1_k127_4855765_2 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.0000000000000000000000000000000003027 136.0
SX1_k127_4855765_3 pfam nmd3 K07562 - - 0.000000007106 60.0
SX1_k127_4855765_4 Protein of unknown function (DUF424) K09148 - - 0.00001771 48.0
SX1_k127_4863236_0 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 323.0
SX1_k127_4863236_1 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 306.0
SX1_k127_4863236_2 ATPases associated with a variety of cellular activities K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 301.0
SX1_k127_4863236_3 Zinc-uptake complex component A periplasmic K02077,K09815 - - 0.000000000000000000000000000000000000000000000000000000000000003738 226.0
SX1_k127_4863236_4 iron dependent repressor K03709 - - 0.00000000000000000000000000000001071 128.0
SX1_k127_4888162_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 474.0
SX1_k127_4888162_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 465.0
SX1_k127_4888162_2 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000002518 209.0
SX1_k127_4902687_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 408.0
SX1_k127_4902687_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 321.0
SX1_k127_4931553_0 acid binding OB-fold tRNA helicase-type K07463 - - 1.037e-252 790.0
SX1_k127_4940345_0 TIGRFAM TraB family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 476.0
SX1_k127_4940345_1 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000318 218.0
SX1_k127_4940345_2 Belongs to the UPF0305 family - - - 0.000000000000000000000000000000000000000000000004964 177.0
SX1_k127_4940345_3 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000002911 72.0
SX1_k127_4957582_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 6.47e-263 812.0
SX1_k127_4957582_1 Nitrogenase component 1 type Oxidoreductase K02591 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 515.0
SX1_k127_4968858_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 467.0
SX1_k127_4968858_1 PFAM Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 415.0
SX1_k127_4968858_2 K+-transporting ATPase, c chain K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000004268 163.0
SX1_k127_4990018_0 - - - - 0.0000000000000000000000000000000000000000000001268 176.0
SX1_k127_4990018_1 Archaebacterial flagellin K07330 - - 0.00000000000000000000000000000000000000000005266 165.0
SX1_k127_4990018_2 Archaeal flagellar protein F K07329 - - 0.0000000000000000000000000000000002847 137.0
SX1_k127_4990018_3 KaiC K07331 - - 0.00000000000000000000839 93.0
SX1_k127_4999038_0 PFAM dihydropteroate synthase, DHPS - - - 6.626e-195 629.0
SX1_k127_4999038_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 590.0
SX1_k127_4999038_2 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 451.0
SX1_k127_4999038_3 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 287.0
SX1_k127_4999038_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 291.0
SX1_k127_4999038_5 PFAM chaperonin Cpn60 TCP-1 K22447 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001141 274.0
SX1_k127_4999038_6 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000111 238.0
SX1_k127_4999038_7 Uncharacterized protein, homolog of nitrogen regulatory protein PII - - - 0.00000000000000000000000000000000000000000000000003285 181.0
SX1_k127_4999038_8 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000000002369 145.0
SX1_k127_5028074_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.572e-238 748.0
SX1_k127_5028074_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000005879 202.0
SX1_k127_5028074_2 Kef-type K transport systems membrane components - - - 0.000000000451 67.0
SX1_k127_5028074_3 - - - - 0.0006466 48.0
SX1_k127_5044456_0 PFAM ATPase, BadF BadG BcrA BcrD type - - - 1.123e-217 680.0
SX1_k127_5044456_1 Glycosyl hydrolase family 57 K07405 - 3.2.1.1 9.947e-197 625.0
SX1_k127_5044456_10 Starch synthase catalytic K16150 - 2.4.1.11 0.0000000000000000000000000000000000000000000000406 184.0
SX1_k127_5044456_2 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 609.0
SX1_k127_5044456_3 methanogenesis marker protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 451.0
SX1_k127_5044456_4 Belongs to the UPF0288 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 436.0
SX1_k127_5044456_5 Glycogen debranching enzyme N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 345.0
SX1_k127_5044456_6 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000105 235.0
SX1_k127_5044456_7 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.0000000000000000000000000000000000000000000000000000001325 200.0
SX1_k127_5044456_8 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.000000000000000000000000000000000000000000000000000001633 196.0
SX1_k127_5044456_9 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.0000000000000000000000000000000000000000000000000302 183.0
SX1_k127_5049593_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 5.208e-303 941.0
SX1_k127_5049593_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 8.628e-200 632.0
SX1_k127_5049593_2 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000004274 235.0
SX1_k127_5049593_3 PFAM Ribonuclease III - - - 0.0000000000000000000000000000000000000000000000000000000000586 212.0
SX1_k127_5049593_4 Domain of unknown function (DUF1805) - - - 0.000000000000000000000000000005073 124.0
SX1_k127_5049593_5 Peptidase family M23 - - - 0.000007976 48.0
SX1_k127_5068080_0 Sodium Bile acid symporter family K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000177 273.0
SX1_k127_5068080_1 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009703 280.0
SX1_k127_5068080_2 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000003917 215.0
SX1_k127_5068080_3 DGC domain - - - 0.0000000000000000000002722 103.0
SX1_k127_5068080_4 Putative zinc ribbon domain - - - 0.00000000000000000177 89.0
SX1_k127_5076804_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 514.0
SX1_k127_5076804_1 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000001628 229.0
SX1_k127_5076804_2 - - - - 0.000000000000000000000000000000000000002628 151.0
SX1_k127_5102271_0 Protein of unknown function (DUF460) K09150 - - 4.548e-226 719.0
SX1_k127_5102271_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 441.0
SX1_k127_5102271_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 395.0
SX1_k127_5102271_3 PFAM PP-loop domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 370.0
SX1_k127_5102271_4 Rio2, N-terminal K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 339.0
SX1_k127_5102271_5 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 326.0
SX1_k127_5102271_6 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007797 276.0
SX1_k127_5102271_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004029 271.0
SX1_k127_5102271_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006568 259.0
SX1_k127_5102271_9 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000005953 66.0
SX1_k127_5114174_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 543.0
SX1_k127_5114174_1 - K00960 - 2.7.7.6 0.000000000000000000000007071 104.0
SX1_k127_5132401_0 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 321.0
SX1_k127_5132401_1 - - - - 0.0000000000000000000000000000000000000000000000000000002418 209.0
SX1_k127_5132401_2 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00000009054 53.0
SX1_k127_513468_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 571.0
SX1_k127_513468_1 helicase activity K06915 - - 0.0000000002872 68.0
SX1_k127_5142552_0 Cellulosome anchoring protein cohesin region - - - 0.000001127 58.0
SX1_k127_5147826_0 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.00000000000000000000000000000000000000000000002472 175.0
SX1_k127_5147826_1 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000002276 142.0
SX1_k127_5147826_2 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000000000000000001436 136.0
SX1_k127_5147826_3 Domain of unknown function (DUF4040) - - - 0.00000000000000000004538 91.0
SX1_k127_5147826_4 Membrane bound hydrogenase - - - 0.00000000000000000005663 95.0
SX1_k127_5151474_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000003474 190.0
SX1_k127_5151474_1 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.0000000000393 74.0
SX1_k127_5160141_0 PFAM UbiA prenyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000007913 209.0
SX1_k127_5160141_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.00000000000000000000000000000000000000000000000000954 190.0
SX1_k127_5169671_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 490.0
SX1_k127_5169671_1 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000002918 206.0
SX1_k127_5169671_2 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000145 186.0
SX1_k127_5169671_3 Peptidase family M23 - - - 0.000000000000000000000000000000000000004859 152.0
SX1_k127_5169671_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000001644 132.0
SX1_k127_5169671_5 - - - - 0.000000000000000000009335 103.0
SX1_k127_5169671_6 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.000000000001424 67.0
SX1_k127_5188262_0 SMART Elongator protein 3 MiaB NifB - - - 5.561e-233 732.0
SX1_k127_5188262_1 phosphoesterase RecJ domain protein - - - 9.322e-208 656.0
SX1_k127_5188262_2 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 498.0
SX1_k127_5188262_3 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001233 271.0
SX1_k127_5188262_4 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000006229 175.0
SX1_k127_5188262_5 PFAM PRC-barrel domain - - - 0.00000065 51.0
SX1_k127_5201028_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 387.0
SX1_k127_5201028_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 311.0
SX1_k127_5201028_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 258.0
SX1_k127_5201028_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 0.00000000000000000000000000000000000000000000001908 173.0
SX1_k127_5201028_4 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000000000000008668 155.0
SX1_k127_5201028_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00001506 47.0
SX1_k127_5201028_6 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.00004046 47.0
SX1_k127_5228061_0 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00581 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 534.0
SX1_k127_5228061_1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00580 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 359.0
SX1_k127_5228061_2 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00579 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 338.0
SX1_k127_5228061_3 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00578 - 2.1.1.86 0.00000000000000000000000000000000004148 136.0
SX1_k127_5228061_4 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000006948 54.0
SX1_k127_5242437_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.704e-269 840.0
SX1_k127_5242437_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000004925 163.0
SX1_k127_5242437_2 - - - - 0.0000000000000000000000000000000008621 136.0
SX1_k127_5242437_3 - - - - 0.0000000000000000000000000011 115.0
SX1_k127_5251471_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 546.0
SX1_k127_5251471_1 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 436.0
SX1_k127_5251471_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000002238 175.0
SX1_k127_5251471_3 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0000000000000000000003444 97.0
SX1_k127_5264958_0 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 412.0
SX1_k127_5264958_1 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 402.0
SX1_k127_5264958_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 354.0
SX1_k127_5264958_3 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 327.0
SX1_k127_5264958_4 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008059 254.0
SX1_k127_5264958_5 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0000000000000000000008381 95.0
SX1_k127_5265171_0 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaH K14099 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 286.0
SX1_k127_5265171_1 Predicted membrane protein (DUF2105) K14098 - - 0.0000000000000000000000000000000000000000000000000000000000004452 220.0
SX1_k127_5265171_2 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.0000000000000000000000000000000000000000000000000000131 192.0
SX1_k127_5265171_3 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaF K14097 - - 0.00000000000000000000000000000000000000000000000001867 181.0
SX1_k127_5265171_4 - K14100 - - 0.000000003482 59.0
SX1_k127_5287611_0 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 579.0
SX1_k127_5287611_1 Methyltransferase K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 360.0
SX1_k127_5287611_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000003271 111.0
SX1_k127_5296744_0 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 420.0
SX1_k127_5296744_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 347.0
SX1_k127_5296744_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 317.0
SX1_k127_5296744_3 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007827 264.0
SX1_k127_5296744_4 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001094 255.0
SX1_k127_5296744_5 - - - - 0.0000000000000000000000000000000000000002896 156.0
SX1_k127_5333048_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0000000000000000000000000000000000000000000000000000000000000000136 226.0
SX1_k127_5333048_1 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000002412 177.0
SX1_k127_5333048_2 PFAM ribosomal protein S8E K02995 - - 0.0000000000000000000000000000000000000000000000008949 177.0
SX1_k127_5333048_3 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.000000000000000000000000000000000000000000004699 167.0
SX1_k127_5333048_4 - - - - 0.00000000000000000000000000000000000000000008833 163.0
SX1_k127_5333048_5 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000000000000000000000000000000000001817 158.0
SX1_k127_5342362_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 389.0
SX1_k127_5342362_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 357.0
SX1_k127_5342362_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.000000000000000000000000000000000000000000000000000000000000000000004911 234.0
SX1_k127_5359560_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.946e-204 641.0
SX1_k127_5359560_1 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001667 251.0
SX1_k127_5359560_2 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000004003 229.0
SX1_k127_5359560_3 zinc finger, SWIM - - - 0.0000000000000000000000000000002829 125.0
SX1_k127_5359560_4 - - - - 0.0000000002948 64.0
SX1_k127_5359560_5 PFAM CBS domain - - - 0.000000008726 57.0
SX1_k127_5362782_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.271e-230 719.0
SX1_k127_5362782_1 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 605.0
SX1_k127_5362782_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 436.0
SX1_k127_5362782_3 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000002708 202.0
SX1_k127_5362782_4 transcriptional - - - 0.00000002392 63.0
SX1_k127_5396864_0 Involved in cell shape control K22222 - - 2.037e-203 639.0
SX1_k127_5396864_1 PFAM amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 508.0
SX1_k127_5408814_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 600.0
SX1_k127_5408814_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 548.0
SX1_k127_5408814_2 MviN-like protein - - - 0.000000000000000000000000000000000000000000000000000000000001406 216.0
SX1_k127_5429863_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.235e-231 724.0
SX1_k127_5429863_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 387.0
SX1_k127_5429863_10 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000002704 76.0
SX1_k127_5429863_2 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 347.0
SX1_k127_5429863_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.000000000000000000000000000000000000000000000000000001055 199.0
SX1_k127_5429863_4 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.000000000000000000000000000000000000000000377 158.0
SX1_k127_5429863_5 binds to the 23S rRNA K02921 - - 0.00000000000000000000000000000000000000003045 154.0
SX1_k127_5429863_6 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000000000000000000000002706 143.0
SX1_k127_5429863_7 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0000000000000000000000000000000000761 139.0
SX1_k127_5429863_8 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.0000000000000000000000009534 104.0
SX1_k127_5429863_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000000000000000003825 90.0
SX1_k127_5456237_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 476.0
SX1_k127_5456237_1 - - - - 0.00000000000000000000000000004592 123.0
SX1_k127_5456237_2 Hemerythrin HHE cation binding domain - - - 0.000001247 56.0
SX1_k127_5457008_0 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002822 286.0
SX1_k127_5460387_0 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 438.0
SX1_k127_5460387_1 PFAM Tetratricopeptide - - - 0.00000000000000192 82.0
SX1_k127_5461061_0 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000002905 154.0
SX1_k127_5461061_1 Cupin domain - - - 0.000000000000000000000000000000000003351 147.0
SX1_k127_5473295_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 593.0
SX1_k127_5473295_1 PFAM TM2 domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002036 273.0
SX1_k127_5473295_2 PFAM Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000626 262.0
SX1_k127_5473295_3 PFAM TM2 domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000006439 220.0
SX1_k127_5473295_4 Membrane - - - 0.000000000000000000000000000000000000000000000000000000001959 208.0
SX1_k127_5473295_5 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000009347 188.0
SX1_k127_5473295_6 Cupin domain - - - 0.0000000000000000000000000000000000000000000000008666 179.0
SX1_k127_5473295_7 - - - - 0.00000000000000000000000000001643 120.0
SX1_k127_5473295_8 Protein of unknown function (DUF1622) - - - 0.00000000000008457 73.0
SX1_k127_5473295_9 - - - - 0.00000000006576 63.0
SX1_k127_5533498_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1419.0
SX1_k127_5533498_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 9.43e-276 857.0
SX1_k127_5533498_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 599.0
SX1_k127_5533498_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001282 233.0
SX1_k127_5533498_4 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000000000000000000000000000001247 149.0
SX1_k127_5533498_5 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 0.00000000000002355 78.0
SX1_k127_5555530_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 5.652e-269 833.0
SX1_k127_5555530_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.476e-253 786.0
SX1_k127_5555530_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 566.0
SX1_k127_5555530_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 309.0
SX1_k127_5555530_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 297.0
SX1_k127_5555530_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000008694 134.0
SX1_k127_5555530_6 ATP synthase subunit C K02124 - - 0.00000000000000000000002859 100.0
SX1_k127_5572505_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1223.0
SX1_k127_5572505_1 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 364.0
SX1_k127_5572505_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 342.0
SX1_k127_5572505_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009608 280.0
SX1_k127_5572505_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000007819 263.0
SX1_k127_5572505_5 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009973 249.0
SX1_k127_5572505_6 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000002655 188.0
SX1_k127_5572505_7 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000001621 182.0
SX1_k127_5572505_8 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.0000000000000000000000000000000000000000000000002384 181.0
SX1_k127_5572505_9 Alpha/beta hydrolase family K06889 - - 0.0005772 48.0
SX1_k127_564015_0 Involved in regulation of DNA replication K10725 - - 1.538e-207 652.0
SX1_k127_564015_1 PFAM Aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 584.0
SX1_k127_564015_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 545.0
SX1_k127_564015_3 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000004238 237.0
SX1_k127_564015_4 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001657 234.0
SX1_k127_564015_5 - - - - 0.0000000000000000000001455 104.0
SX1_k127_564015_6 Belongs to the UPF0434 family - - - 0.00000000000000000008307 89.0
SX1_k127_5672601_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 384.0
SX1_k127_5672601_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002024 276.0
SX1_k127_5672601_2 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000001735 170.0
SX1_k127_5672601_3 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000000958 148.0
SX1_k127_5672601_4 SigmaK-factor processing regulatory protein BofA K06317 - - 0.000000000000000141 83.0
SX1_k127_573016_0 Acetone carboxylase gamma K10856 - 6.4.1.6 0.000000000000000000000000000000000116 134.0
SX1_k127_573016_1 ligase activity K01474,K10854 - 3.5.2.14,6.4.1.6 0.000000000000000000000000000000004547 138.0
SX1_k127_573016_2 ligase activity K10856 - 6.4.1.6 0.000000000000000000004329 96.0
SX1_k127_573016_3 Amidohydrolase - - - 0.0000000002066 65.0
SX1_k127_5757537_0 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 330.0
SX1_k127_5757537_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 312.0
SX1_k127_5757537_2 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000000000000000000000000000000000000000000000000001525 201.0
SX1_k127_5759860_0 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 305.0
SX1_k127_5759860_1 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001795 274.0
SX1_k127_5759860_2 PFAM methyltransferase small K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000003747 209.0
SX1_k127_5759860_3 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000000000000000000000000007351 169.0
SX1_k127_5759860_4 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000000000000000000000000000004868 151.0
SX1_k127_5759860_5 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000001029 126.0
SX1_k127_5759860_6 PBS lyase HEAT-like repeat - - - 0.0000000000000000000001585 109.0
SX1_k127_5759860_7 COG3364 Zn-ribbon containing protein K07163 - - 0.000006337 57.0
SX1_k127_5763243_0 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 595.0
SX1_k127_5763243_1 - - - - 0.000000000000000000000000000000000006578 140.0
SX1_k127_5763243_2 protein N-acetylglucosaminyltransferase activity K12600 - - 0.0000000000000000000000000000000006868 142.0
SX1_k127_5763243_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000017 93.0
SX1_k127_5783021_0 Helix-hairpin-helix domain K02347 - - 1.228e-201 642.0
SX1_k127_5783021_1 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 554.0
SX1_k127_5783021_2 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 405.0
SX1_k127_5783021_3 PFAM Radical SAM domain protein K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 400.0
SX1_k127_5783021_4 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 332.0
SX1_k127_5783021_5 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 288.0
SX1_k127_5783021_6 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000004857 254.0
SX1_k127_5783021_7 iron dependent repressor K03709,K04758 - - 0.0000000000000000000000000000000002059 139.0
SX1_k127_5829279_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 460.0
SX1_k127_5829279_1 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 302.0
SX1_k127_5829279_2 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000003322 234.0
SX1_k127_5829279_3 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000005174 221.0
SX1_k127_5829279_4 H subunit K02107 - - 0.000000007512 61.0
SX1_k127_5829279_5 PFAM transposase, IS4 family protein - - - 0.0000004958 55.0
SX1_k127_5832531_0 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 538.0
SX1_k127_5832531_1 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 421.0
SX1_k127_5832531_2 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 407.0
SX1_k127_5832531_3 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000001324 164.0
SX1_k127_5832531_4 rubredoxin - - - 0.00000000000000000006358 90.0
SX1_k127_5832531_5 PFAM oxidoreductase nitrogenase, component 1 - - - 0.0000000000000000003362 88.0
SX1_k127_5832531_6 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000004698 74.0
SX1_k127_5859252_0 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 498.0
SX1_k127_5859252_1 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 470.0
SX1_k127_5859252_2 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002374 287.0
SX1_k127_5859252_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002863 274.0
SX1_k127_5859252_4 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000455 235.0
SX1_k127_5906158_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 5e-323 1003.0
SX1_k127_5906158_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 384.0
SX1_k127_5906158_2 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 336.0
SX1_k127_5906158_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000551 247.0
SX1_k127_5906158_4 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000001591 229.0
SX1_k127_5906158_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000003027 136.0
SX1_k127_5906158_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.00000000000000000000000000000006092 127.0
SX1_k127_5906158_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000001091 100.0
SX1_k127_5906158_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000006096 84.0
SX1_k127_5906158_9 ArsR transcriptional regulator - - - 0.0000000005733 59.0
SX1_k127_5921080_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 7.984e-233 733.0
SX1_k127_5921080_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 334.0
SX1_k127_5921080_2 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 307.0
SX1_k127_5921080_3 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 291.0
SX1_k127_5921080_4 ABC-type tungstate transport system, periplasmic component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001874 279.0
SX1_k127_5932835_0 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 485.0
SX1_k127_5932835_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 385.0
SX1_k127_5932835_2 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000009198 232.0
SX1_k127_5932835_3 - - - - 0.000000000000000000000000000000000000000000000000000007252 192.0
SX1_k127_5951948_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000003635 222.0
SX1_k127_5951948_1 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000000000055 192.0
SX1_k127_5951948_2 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000000000000000000000000000008747 154.0
SX1_k127_5951948_3 PFAM Ribosomal LX protein K02944 - - 0.0000000000000326 74.0
SX1_k127_5988282_0 arsenite transmembrane transporter activity K03893 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003297 282.0
SX1_k127_5988282_1 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000243 181.0
SX1_k127_6017093_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.211e-252 789.0
SX1_k127_6017093_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 611.0
SX1_k127_6017093_10 - K03686 - - 0.0000000000000000000347 91.0
SX1_k127_6017093_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 465.0
SX1_k127_6017093_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 425.0
SX1_k127_6017093_4 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 327.0
SX1_k127_6017093_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 321.0
SX1_k127_6017093_6 COG1940 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 318.0
SX1_k127_6017093_7 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002199 263.0
SX1_k127_6017093_8 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000441 257.0
SX1_k127_6017093_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000001045 242.0
SX1_k127_6027794_0 SMART Elongator protein 3 MiaB NifB K06936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 383.0
SX1_k127_6027794_1 LOR SDH bifunctional enzyme conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 345.0
SX1_k127_6027794_2 - - - - 0.000001669 53.0
SX1_k127_6027794_3 SMART Elongator protein 3 MiaB NifB K06936 - - 0.000002897 49.0
SX1_k127_6060884_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 6.399e-218 685.0
SX1_k127_6060884_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 5.82e-201 629.0
SX1_k127_6060884_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000005756 55.0
SX1_k127_6060884_2 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 356.0
SX1_k127_6060884_3 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 344.0
SX1_k127_6060884_4 B-block binding subunit of TFIIIC - - - 0.000000000000000000000000000000000000000000008879 166.0
SX1_k127_6060884_5 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000009206 165.0
SX1_k127_6060884_6 - - - - 0.00000000000000000000000000000000004765 140.0
SX1_k127_6060884_7 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000000000001459 125.0
SX1_k127_6060884_8 PBS lyase HEAT-like repeat - - - 0.0000000000000000002308 98.0
SX1_k127_6060884_9 UPF0056 membrane protein K05595 - - 0.0000000000000000009006 88.0
SX1_k127_6145254_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1551.0
SX1_k127_6145254_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 1.672e-220 686.0
SX1_k127_6145254_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.00000000000000000000000000000000000006892 146.0
SX1_k127_6150666_0 PFAM SMC domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 302.0
SX1_k127_6150666_1 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000005682 216.0
SX1_k127_6150666_2 Prokaryotic homologs of the JAB domain - - - 0.00000000000000000000000000000000000000000000003903 171.0
SX1_k127_6150666_3 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000007361 177.0
SX1_k127_6150666_4 FAD dependent oxidoreductase - - - 0.000007442 58.0
SX1_k127_6166182_0 - - - - 0.00000000000000000000000000001097 121.0
SX1_k127_6166182_1 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000003053 115.0
SX1_k127_6166182_2 PAS domain - - - 0.000000000000000000000000000485 118.0
SX1_k127_6171873_0 - - - - 0.000000000000000000000000000000000000000000000007419 181.0
SX1_k127_6171873_1 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000001069 156.0
SX1_k127_6171873_2 AAA domain K07133 - - 0.000000000000000007832 84.0
SX1_k127_6177329_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 554.0
SX1_k127_6177329_1 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 544.0
SX1_k127_6177329_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 391.0
SX1_k127_6177329_3 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 314.0
SX1_k127_6221949_0 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000005729 258.0
SX1_k127_6221949_1 - - - - 0.0000000000000000000000000000000000000000000000000000000003994 216.0
SX1_k127_6221949_2 - - - - 0.0000000000000001708 87.0
SX1_k127_6227598_0 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 354.0
SX1_k127_6227598_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 292.0
SX1_k127_6227598_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000001098 232.0
SX1_k127_6227598_3 PFAM Amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000000001019 209.0
SX1_k127_6227598_4 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000000000009055 115.0
SX1_k127_6231352_0 Uncharacterized membrane protein (DUF2298) - - - 4.904e-205 658.0
SX1_k127_6231352_1 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000000000000000005614 194.0
SX1_k127_6231352_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000002565 137.0
SX1_k127_6231352_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000000001891 127.0
SX1_k127_6231352_4 Binds to the 23S rRNA K02896 - - 0.0000000000000000000000000006813 113.0
SX1_k127_6273997_0 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 573.0
SX1_k127_6273997_1 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 473.0
SX1_k127_6273997_2 PFAM metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 290.0
SX1_k127_6273997_3 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000000000001668 165.0
SX1_k127_6273997_4 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.0000000000000000000000000000000000002273 147.0
SX1_k127_6273997_5 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000002046 87.0
SX1_k127_6273997_6 PFAM YHS domain - - - 0.00000000002525 68.0
SX1_k127_6282723_0 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 334.0
SX1_k127_6282723_1 TIGRFAM ribosomal protein L30P K02907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002761 243.0
SX1_k127_6282723_2 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000000000000000000006996 229.0
SX1_k127_6282723_3 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000969 163.0
SX1_k127_6282723_4 binds to the 23S rRNA K02885 - - 0.0000000000000000000000000000000000001505 144.0
SX1_k127_6282723_5 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000001835 49.0
SX1_k127_6301647_0 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 1.048e-300 926.0
SX1_k127_6301647_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 361.0
SX1_k127_6301647_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000000000000000000000000000002702 123.0
SX1_k127_630650_0 Conserved region in glutamate synthase - - - 1.737e-291 900.0
SX1_k127_630650_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003217 277.0
SX1_k127_632303_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 562.0
SX1_k127_632303_1 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 324.0
SX1_k127_646293_0 PFAM type II secretion system protein E K07332 - - 2.338e-259 809.0
SX1_k127_649554_0 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000002733 231.0
SX1_k127_649554_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000002329 191.0
SX1_k127_649554_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000009559 82.0
SX1_k127_702899_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 6.689e-219 692.0
SX1_k127_702899_1 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 7.916e-194 610.0
SX1_k127_702899_10 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000003479 109.0
SX1_k127_702899_11 - - - - 0.0000000000000004524 85.0
SX1_k127_702899_2 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 425.0
SX1_k127_702899_3 archaeal Zn-finger protein - - - 0.000000000000000000000000000000000000000000000000000385 190.0
SX1_k127_702899_4 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000000000003666 183.0
SX1_k127_702899_5 Domain of unknown function (DUF371) K09738 - - 0.0000000000000000000000000000000000000003196 153.0
SX1_k127_702899_6 Type II secretion system (T2SS), protein F K07333 - - 0.000000000000000000000000000000000000005713 147.0
SX1_k127_702899_7 - - - - 0.00000000000000000000000000000000004716 144.0
SX1_k127_702899_8 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.000000000000000000000000000000315 128.0
SX1_k127_702899_9 - - - - 0.000000000000000000000000000001853 124.0
SX1_k127_715317_0 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 289.0
SX1_k127_715317_1 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000000000000000000000000000006069 233.0
SX1_k127_723196_0 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 370.0
SX1_k127_723196_1 Glycogen debranching enzyme N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 283.0
SX1_k127_723196_2 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000002848 79.0
SX1_k127_829197_0 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 292.0
SX1_k127_829197_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000009256 233.0
SX1_k127_829197_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000003639 228.0
SX1_k127_829197_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000003241 218.0
SX1_k127_829197_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000008996 200.0
SX1_k127_829197_5 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000000000000000006493 179.0
SX1_k127_829197_6 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.0000000000000000000000000000000000000000000607 164.0
SX1_k127_829197_7 PFAM Ribosomal protein K02912 - - 0.00000000000000000000000000000000008925 139.0
SX1_k127_829197_8 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.000000000000000000000002036 102.0
SX1_k127_829197_9 Binds to the 23S rRNA K02885 - - 0.000000000009057 67.0
SX1_k127_852296_0 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 304.0
SX1_k127_852296_1 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 288.0
SX1_k127_874823_0 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 507.0
SX1_k127_874823_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.0000000000000000000000000000000001399 141.0
SX1_k127_875819_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 378.0
SX1_k127_875819_1 SMART Elongator protein 3 MiaB NifB K15865 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 355.0
SX1_k127_875819_2 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 329.0
SX1_k127_875819_3 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 304.0
SX1_k127_875819_4 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000004154 171.0
SX1_k127_875819_5 protein conserved in bacteria (DUF2179) - - - 0.00002443 47.0
SX1_k127_877986_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.533e-296 916.0
SX1_k127_877986_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 1.033e-233 731.0
SX1_k127_877986_2 Protein of unknown function (DUF4013) - - - 0.000000000000000000000000000000000000000000000000000007929 197.0
SX1_k127_881744_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 569.0
SX1_k127_881744_1 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 287.0
SX1_k127_881744_2 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002031 264.0
SX1_k127_892242_0 Methanogenesis marker protein 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
SX1_k127_892242_1 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007807 245.0
SX1_k127_892242_2 - - - - 0.000000000000000000000000000000000000000000000000002346 192.0
SX1_k127_892242_3 PQ loop repeat K15383 - - 0.0000000000000000000008502 97.0
SX1_k127_892242_4 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000004115 67.0
SX1_k127_898779_0 PHP C-terminal domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 427.0
SX1_k127_898779_1 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 295.0
SX1_k127_898779_2 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 284.0
SX1_k127_898779_3 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000001055 69.0
SX1_k127_899226_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 359.0
SX1_k127_899226_1 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001333 265.0
SX1_k127_899226_2 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000002235 220.0
SX1_k127_899226_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000000002489 200.0
SX1_k127_899226_4 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.00000000000000000000000000000000009107 133.0
SX1_k127_899906_0 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 440.0
SX1_k127_899906_1 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000003325 142.0
SX1_k127_899906_2 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000003111 88.0
SX1_k127_903426_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 522.0
SX1_k127_903426_1 Replication factor C K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 368.0
SX1_k127_903426_2 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 334.0
SX1_k127_903426_3 pfam nmd3 K07562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 301.0
SX1_k127_903426_4 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000001945 260.0
SX1_k127_903426_5 Pfam:DUF137 K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000001121 252.0
SX1_k127_903426_6 PFAM AIR synthase related protein K07388 - - 0.0000000000000000000000000001798 117.0
SX1_k127_903426_7 Methyltransferase - - - 0.0000000000000002745 87.0
SX1_k127_903426_8 Protein of unknown function (DUF424) K09148 - - 0.0000000003574 62.0
SX1_k127_927833_0 in RNase L inhibitor, RLI K06174 - - 1.342e-281 876.0
SX1_k127_927833_1 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 380.0
SX1_k127_927833_2 RNase L inhibitor, RLI - - - 0.00000000000000000000000001647 112.0