Overview

ID MAG03642
Name SX2_bin.26
Sample SMP0092
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Eutrophobiales
Family Eutrophobiaceae
Genus 2-02-FULL-47-50
Species
Assembly information
Completeness (%) 64.77
Contamination (%) 1.65
GC content (%) 56.0
N50 (bp) 3,055
Genome size (bp) 1,343,404

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1493

Gene name Description KEGG GOs EC E-value Score Sequence
SX2_k127_1000110_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000756 222.0
SX2_k127_1000110_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000011 176.0
SX2_k127_1000110_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000001397 175.0
SX2_k127_1018716_0 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 331.0
SX2_k127_1018716_1 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000000000000000000000000004746 141.0
SX2_k127_1023339_0 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 603.0
SX2_k127_1023339_1 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000000000000000000000000000000000000000000000000000000000000000006389 232.0
SX2_k127_1023339_3 tryptophan synthase subunit beta - - - 0.00000000000000001233 87.0
SX2_k127_1023339_4 ABC transporter transmembrane region - - - 0.00002618 48.0
SX2_k127_1027729_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.004e-267 835.0
SX2_k127_1027729_1 Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000006255 74.0
SX2_k127_1029898_0 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 425.0
SX2_k127_1029898_1 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000008465 140.0
SX2_k127_1029898_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000002306 68.0
SX2_k127_1044657_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 7.007e-200 632.0
SX2_k127_1044657_1 PAS fold K07708 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000009466 233.0
SX2_k127_1046473_0 Gliding motility protein GldG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 478.0
SX2_k127_1046473_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 304.0
SX2_k127_1046473_2 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000001432 149.0
SX2_k127_1055092_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 357.0
SX2_k127_1055092_1 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000001629 119.0
SX2_k127_1055293_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.476e-223 701.0
SX2_k127_1075110_0 PFAM Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 355.0
SX2_k127_1075110_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00966,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 0.000000000000000000000000000000000000000000001598 168.0
SX2_k127_1124604_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 304.0
SX2_k127_1124604_1 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000006163 168.0
SX2_k127_1124604_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - 0.0000000000000000000000000000000000000000001758 171.0
SX2_k127_1124604_3 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000001795 164.0
SX2_k127_1124604_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000003509 87.0
SX2_k127_1150627_0 ATPase domain of DNA mismatch repair MUTS family K03555 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 1.627e-315 987.0
SX2_k127_1150627_1 Molecular chaperone. Has ATPase activity K04079 - - 6.509e-216 679.0
SX2_k127_1150627_2 Tetratricopeptide repeat - - - 0.000000000000002111 85.0
SX2_k127_1150627_3 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.0000000000002387 79.0
SX2_k127_1150627_4 PFAM ABC transporter K01995 - - 0.00000006605 54.0
SX2_k127_1151294_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000001207 244.0
SX2_k127_1151294_1 crp fnr family K01420 - - 0.0000000000000000000000000000000000000000000000007206 183.0
SX2_k127_1171420_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 5.68e-201 638.0
SX2_k127_1171420_1 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 296.0
SX2_k127_1171420_2 PFAM Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003961 277.0
SX2_k127_1171420_3 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000001379 159.0
SX2_k127_1171420_4 competence protein ComEA K02237 - - 0.00000000000000096 80.0
SX2_k127_1193130_0 HpcH/HpaI aldolase/citrate lyase family K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002843 274.0
SX2_k127_1193130_1 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000004381 267.0
SX2_k127_1193130_2 Small membrane protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000001387 159.0
SX2_k127_1193130_3 COG1226 Kef-type K transport systems - - - 0.0000000000000001341 79.0
SX2_k127_1197913_0 PFAM Transglutaminase-like superfamily K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 567.0
SX2_k127_1197913_1 Protein of unknown function DUF58 - - - 0.00000000000002488 74.0
SX2_k127_1221435_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 361.0
SX2_k127_1221435_1 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000004459 121.0
SX2_k127_1221435_2 Protein of unknown function, DUF484 K09921 - - 0.000000000000000005439 92.0
SX2_k127_123099_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 406.0
SX2_k127_123099_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000009401 222.0
SX2_k127_123862_0 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 371.0
SX2_k127_123862_1 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000001102 208.0
SX2_k127_123862_2 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000000000000000000000001059 125.0
SX2_k127_123862_3 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000000000004696 108.0
SX2_k127_1252052_0 Heat shock 70 kDa protein K04043 - - 0.0 1020.0
SX2_k127_1252052_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 520.0
SX2_k127_1252052_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 391.0
SX2_k127_1252052_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 344.0
SX2_k127_1252052_4 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 352.0
SX2_k127_1252052_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001479 277.0
SX2_k127_1252052_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000009403 172.0
SX2_k127_1252052_7 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000002068 139.0
SX2_k127_1252052_8 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000002037 114.0
SX2_k127_1274310_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 346.0
SX2_k127_1274310_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000008856 207.0
SX2_k127_1274310_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000002592 203.0
SX2_k127_130025_0 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 1.227e-212 665.0
SX2_k127_130025_1 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 298.0
SX2_k127_130025_2 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000002778 205.0
SX2_k127_130025_3 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.000000000000000000000000000000000000000000002747 170.0
SX2_k127_130025_4 Belongs to the BolA IbaG family K05527 - - 0.000000000001163 69.0
SX2_k127_1332325_0 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 324.0
SX2_k127_1332325_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000003819 159.0
SX2_k127_1346049_0 )-iron permease K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 320.0
SX2_k127_1346049_1 - - - - 0.0000000000000000000000000000000000000000004949 166.0
SX2_k127_1356419_0 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 363.0
SX2_k127_1356419_1 COG0811 Biopolymer transport proteins K03561 - - 0.000000000000000000000000000002321 125.0
SX2_k127_1359622_0 TIGRFAM Formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 3.949e-255 794.0
SX2_k127_1359622_1 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 - 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 415.0
SX2_k127_1359622_2 formylmethanofuran dehydrogenase K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000008064 214.0
SX2_k127_1359622_3 GXGXG motif K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000002209 185.0
SX2_k127_1359622_4 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000002164 162.0
SX2_k127_1359622_5 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 0.0000002604 52.0
SX2_k127_1397777_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.078e-199 630.0
SX2_k127_1397777_1 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05559 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 301.0
SX2_k127_1411043_0 Dolichol-phosphate mannosyltransferase K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000023 264.0
SX2_k127_1411043_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000006892 209.0
SX2_k127_1411043_2 PFAM lipid A biosynthesis domain protein - - - 0.000000000000000000000000000000506 124.0
SX2_k127_1411043_3 PFAM CAAX amino terminal protease family K07052 - - 0.00000000194 61.0
SX2_k127_14197_0 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004866 252.0
SX2_k127_14197_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000727 200.0
SX2_k127_1423895_0 ATPase (AAA superfamily) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 335.0
SX2_k127_1423895_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000003397 186.0
SX2_k127_143448_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 496.0
SX2_k127_143448_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000008626 176.0
SX2_k127_143448_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000009952 102.0
SX2_k127_143448_3 Zinc-finger domain - - - 0.000000000000000000005701 93.0
SX2_k127_143448_4 Mitochondrial fission ELM1 K07276 - - 0.0000000001891 63.0
SX2_k127_1444124_0 S-adenosylmethionine-dependent methyltransferase K06969,K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.191,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000001152 257.0
SX2_k127_1444124_1 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000003782 175.0
SX2_k127_1444124_2 Protein chain release factor B K15034 - - 0.00000000000000000000000000000000000000000001394 165.0
SX2_k127_1444124_3 Protein of unknown function (DUF3012) - - - 0.000000000001348 67.0
SX2_k127_1465929_0 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001205 279.0
SX2_k127_1465929_1 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.000000000000000000000000000000000000000000000000000000000000000000001793 243.0
SX2_k127_1465929_2 - - - - 0.000002807 51.0
SX2_k127_1477638_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 451.0
SX2_k127_1477638_1 Type II secretion system K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000278 228.0
SX2_k127_1487899_0 DNA segregation ATPase FtsK SpoIIIE K03466 - - 1.817e-239 753.0
SX2_k127_1487899_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000001271 139.0
SX2_k127_1497070_0 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000003986 181.0
SX2_k127_1501184_0 Extracellular solute-binding protein, family 5 - - - 2.031e-283 884.0
SX2_k127_1501184_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 381.0
SX2_k127_1501184_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002592 267.0
SX2_k127_1501719_0 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001265 261.0
SX2_k127_1501719_1 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.000000000000000000008757 97.0
SX2_k127_1501719_2 type IV pilus modification protein PilV K02671 - - 0.0000000000000002978 81.0
SX2_k127_1501719_3 type 4 fimbrial pilin related transmembrane protein K08084 - - 0.0000000000262 71.0
SX2_k127_1503069_0 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 373.0
SX2_k127_1503069_1 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 307.0
SX2_k127_1509222_0 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 457.0
SX2_k127_1509222_1 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 346.0
SX2_k127_1509222_2 HflC and HflK could regulate a protease K04087 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 296.0
SX2_k127_1509222_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.0000000000000000000000000005881 118.0
SX2_k127_1509222_4 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000009145 76.0
SX2_k127_1512079_0 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 491.0
SX2_k127_1512079_1 His Kinase A (phosphoacceptor) domain K07679 - 2.7.13.3 0.0000000000000000000000000000001748 129.0
SX2_k127_1539509_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 323.0
SX2_k127_1539509_1 component of anaerobic K03533 - - 0.000000000000000939 86.0
SX2_k127_1539509_2 PFAM Hypoxia induced protein conserved region - - - 0.000001533 53.0
SX2_k127_1539509_3 serine threonine protein kinase K08282 - 2.7.11.1 0.00002599 49.0
SX2_k127_1542164_0 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 328.0
SX2_k127_1542164_1 Hydrolase K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002054 258.0
SX2_k127_1542164_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000143 251.0
SX2_k127_1542164_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000001173 243.0
SX2_k127_1542993_0 growth of symbiont in host cell K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 301.0
SX2_k127_1542993_1 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000002679 229.0
SX2_k127_1564502_0 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 392.0
SX2_k127_1564502_1 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000238 274.0
SX2_k127_1564502_2 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005638 269.0
SX2_k127_1564502_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000002735 222.0
SX2_k127_1564502_4 PFAM Histidine triad (HIT) protein - - - 0.000000000000000000000000000000000000000001231 161.0
SX2_k127_1565991_0 TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.00000000000000000000000000000000000000000000000000001615 198.0
SX2_k127_1565991_1 Phosphorylase superfamily - - - 0.00000000000000000000000001755 117.0
SX2_k127_1571606_0 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 381.0
SX2_k127_1571606_1 serine threonine protein kinase K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000003489 188.0
SX2_k127_1571606_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000002903 143.0
SX2_k127_1571606_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000002577 109.0
SX2_k127_1571606_4 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000009177 97.0
SX2_k127_1571606_5 Plasmid stability protein K21495 - - 0.0000000000000007366 79.0
SX2_k127_1571606_6 Sel1-like repeats. K15475 - - 0.000000004566 59.0
SX2_k127_1585190_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1047.0
SX2_k127_1585190_1 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001143 274.0
SX2_k127_1587164_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 3.547e-219 697.0
SX2_k127_1598803_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 533.0
SX2_k127_1598803_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000298 175.0
SX2_k127_1598803_2 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000003352 168.0
SX2_k127_1598803_3 Domain of unknown function (DUF4115) K15539 - - 0.00000000000001276 76.0
SX2_k127_1625211_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 428.0
SX2_k127_1625211_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000587 280.0
SX2_k127_1625211_2 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000004182 235.0
SX2_k127_1625211_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000002309 220.0
SX2_k127_1625211_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000003572 185.0
SX2_k127_1625211_5 Ribosomal protein S19 K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000005559 158.0
SX2_k127_1625211_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000009912 147.0
SX2_k127_1625211_7 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000153 108.0
SX2_k127_1625211_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001004 76.0
SX2_k127_163437_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 497.0
SX2_k127_163437_1 transport protein CorA K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 471.0
SX2_k127_163437_2 PFAM FecR protein - - - 0.0000000000000000145 92.0
SX2_k127_1653586_0 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 470.0
SX2_k127_1653586_1 GDP-mannose 4,6 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001551 248.0
SX2_k127_1655275_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 561.0
SX2_k127_1655275_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 401.0
SX2_k127_1655275_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005117 280.0
SX2_k127_1677993_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 473.0
SX2_k127_1677993_1 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001734 282.0
SX2_k127_1681960_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 354.0
SX2_k127_1681960_1 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000005637 235.0
SX2_k127_1682232_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 355.0
SX2_k127_1682232_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 340.0
SX2_k127_1682232_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000008162 99.0
SX2_k127_1702951_0 Protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 384.0
SX2_k127_1702951_1 TIGRFAM HAD-superfamily subfamily IIA hydrolase like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008034 278.0
SX2_k127_1709298_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.506e-273 846.0
SX2_k127_1709298_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000002743 161.0
SX2_k127_1709298_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000001842 60.0
SX2_k127_1732959_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000219 260.0
SX2_k127_1732959_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000002126 160.0
SX2_k127_1732959_2 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.00000000000000000000000003491 108.0
SX2_k127_1732959_3 Cytochrome c - - - 0.000000000000006216 79.0
SX2_k127_1732959_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000007043 56.0
SX2_k127_1732960_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.099e-207 654.0
SX2_k127_1732960_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000002271 228.0
SX2_k127_1732960_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000005538 222.0
SX2_k127_1759548_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.273e-307 953.0
SX2_k127_1759548_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 539.0
SX2_k127_1759548_2 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 528.0
SX2_k127_1759548_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 478.0
SX2_k127_1759548_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 422.0
SX2_k127_1759548_5 COGs COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000001923 200.0
SX2_k127_1761210_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 451.0
SX2_k127_1761210_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 360.0
SX2_k127_1761210_2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000001208 113.0
SX2_k127_17657_0 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 404.0
SX2_k127_17657_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000003667 108.0
SX2_k127_17657_2 Sporulation related domain - - - 0.0000000000000000000000001567 113.0
SX2_k127_17657_3 response regulator, receiver K03413 - - 0.000000000000000000001685 98.0
SX2_k127_17657_4 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000001316 74.0
SX2_k127_1769708_0 Signal transduction histidine kinase, phosphotransfer (Hpt) region K13490 - - 1.33e-225 731.0
SX2_k127_177517_0 Helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000201 256.0
SX2_k127_177517_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000002791 230.0
SX2_k127_178521_0 Cytochrome C oxidase subunit II, periplasmic domain protein K00376 - 1.7.2.4 5.405e-320 989.0
SX2_k127_178521_1 FMN_bind - - - 2.131e-298 931.0
SX2_k127_1810915_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1183.0
SX2_k127_1810915_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 297.0
SX2_k127_1810915_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000006059 254.0
SX2_k127_1812988_0 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000001887 170.0
SX2_k127_1813246_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 316.0
SX2_k127_1813246_1 Sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000000000001364 152.0
SX2_k127_1813246_2 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000002834 119.0
SX2_k127_18571_0 COG0845 Membrane-fusion protein K11003,K12542 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 354.0
SX2_k127_18571_1 Transposase K07491 - - 0.000000000000000000000000000000000005267 137.0
SX2_k127_1860734_0 ABC transporter transmembrane region - - - 5.56e-256 799.0
SX2_k127_1860734_1 TIGRFAM type I secretion membrane fusion protein, HlyD - - - 0.0000000001738 67.0
SX2_k127_1862218_0 PFAM NAD dependent epimerase dehydratase family K06118 - 3.13.1.1 2.33e-203 638.0
SX2_k127_1862218_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 435.0
SX2_k127_1862218_2 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 344.0
SX2_k127_1862218_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002768 267.0
SX2_k127_1862218_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000000000000000000000000000000000000000002159 246.0
SX2_k127_1862218_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000001809 162.0
SX2_k127_1862218_6 protein conserved in bacteria K09938 - - 0.0000000004924 68.0
SX2_k127_1875016_0 Histidine kinase K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 406.0
SX2_k127_1884641_0 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 399.0
SX2_k127_1884641_1 Putative DNA-binding domain K09929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 296.0
SX2_k127_1884641_2 - - - - 0.00000000000000000000172 94.0
SX2_k127_1884641_3 - - - - 0.000000001202 65.0
SX2_k127_1891768_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000004979 191.0
SX2_k127_1891768_1 formate dehydrogenase - - - 0.000000000000000002286 93.0
SX2_k127_1897750_0 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 372.0
SX2_k127_1897750_1 Tetratricopeptide repeats - - - 0.000001294 60.0
SX2_k127_1900810_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01761,K10764 - 4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 555.0
SX2_k127_1900810_1 Isocitrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 336.0
SX2_k127_1901302_0 hmm pf01609 K07481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 605.0
SX2_k127_1904749_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.965e-210 660.0
SX2_k127_1904749_1 surface antigen - - - 0.0000000000000000000000000000000000000000000000000278 187.0
SX2_k127_1918626_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 591.0
SX2_k127_1918626_1 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 564.0
SX2_k127_1918626_2 - - - - 0.0001193 46.0
SX2_k127_1937685_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001402 237.0
SX2_k127_1937685_1 Protein of unknown function (DUF2782) - - - 0.000000000000000000000000393 109.0
SX2_k127_1937685_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000009005 81.0
SX2_k127_1939242_0 lysine 2,3-aminomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 297.0
SX2_k127_1939242_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - 0.000000000000000000000000007485 111.0
SX2_k127_1939242_2 COG2199 FOG GGDEF domain K20966 GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007 3.1.4.52 0.000002662 59.0
SX2_k127_1941953_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 558.0
SX2_k127_1943952_0 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 433.0
SX2_k127_1943952_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 427.0
SX2_k127_1943952_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 299.0
SX2_k127_1943952_3 TIGRFAM YD repeat protein - - - 0.0000000000000000000000000000000000000001739 157.0
SX2_k127_198707_0 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 300.0
SX2_k127_198707_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000009293 120.0
SX2_k127_200951_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 405.0
SX2_k127_200951_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 364.0
SX2_k127_200951_2 pfam abc K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 334.0
SX2_k127_200951_3 CHAD - - - 0.00000003397 63.0
SX2_k127_2026490_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.353e-279 865.0
SX2_k127_2026490_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 394.0
SX2_k127_2032717_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 5.582e-263 824.0
SX2_k127_2043329_0 Belongs to the GARS family K01945,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 604.0
SX2_k127_2043329_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 447.0
SX2_k127_2043329_2 Glycine cleavage system T protein K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 398.0
SX2_k127_206301_0 Signal transduction histidine kinase K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 597.0
SX2_k127_206301_1 PFAM Chemotaxis methyl-accepting receptor, signalling - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 461.0
SX2_k127_206301_2 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.000000000000000000000000000000000000000000000000000000007493 205.0
SX2_k127_206301_3 Two component signalling adaptor domain - - - 0.0000000000000000000000000000000000000000000000000004358 188.0
SX2_k127_206900_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 387.0
SX2_k127_206900_1 3'-5' exonuclease K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 365.0
SX2_k127_206900_2 Transposase, Mutator family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 303.0
SX2_k127_210407_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 469.0
SX2_k127_210407_1 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 456.0
SX2_k127_210407_2 phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000002266 151.0
SX2_k127_2122097_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 333.0
SX2_k127_2122097_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 323.0
SX2_k127_2122097_2 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 287.0
SX2_k127_2122097_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000001605 226.0
SX2_k127_2122097_4 - - - - 0.0000000000000000000000000000000000000000000000000006752 185.0
SX2_k127_2122097_5 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000003116 158.0
SX2_k127_2122097_6 Putative addiction module component - - - 0.00000000000000000000009256 100.0
SX2_k127_2124030_0 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000001378 170.0
SX2_k127_2124030_1 EAL domain - - - 0.00000000000000003234 83.0
SX2_k127_2124030_2 Protein of unknown function, DUF484 K09921 - - 0.00000000000009899 80.0
SX2_k127_2137566_0 peptidase, M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 587.0
SX2_k127_2147445_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 5.727e-315 976.0
SX2_k127_2184362_0 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002145 259.0
SX2_k127_2184362_1 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000004915 196.0
SX2_k127_2218244_0 Diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000008536 229.0
SX2_k127_2218244_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000001418 226.0
SX2_k127_2218244_2 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000271 201.0
SX2_k127_2218244_3 diguanylate cyclase - - - 0.0000000000000000338 95.0
SX2_k127_2241152_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 369.0
SX2_k127_2241152_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000093 239.0
SX2_k127_2241152_2 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000000000000000000006613 213.0
SX2_k127_2241152_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.00000004045 55.0
SX2_k127_2250910_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 313.0
SX2_k127_2250910_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 310.0
SX2_k127_2255792_0 peptidase K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 566.0
SX2_k127_2255792_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000005407 166.0
SX2_k127_2255792_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000006019 144.0
SX2_k127_2292112_0 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
SX2_k127_2292112_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000009493 170.0
SX2_k127_2292112_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.00000000000000000000000000000000000000000005365 161.0
SX2_k127_2292112_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000001928 91.0
SX2_k127_2311891_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1 5.856e-218 687.0
SX2_k127_2318566_0 ABC transporter transmembrane region K06148,K12536 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 410.0
SX2_k127_2318566_1 Sulfotransferase domain - - - 0.00000003243 59.0
SX2_k127_2330177_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 316.0
SX2_k127_2330177_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000002393 237.0
SX2_k127_2330177_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000001498 192.0
SX2_k127_2330177_3 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000001905 105.0
SX2_k127_2330177_4 DnaK suppressor protein - - - 0.00000000000000000000006098 102.0
SX2_k127_2341815_0 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000001296 154.0
SX2_k127_2341815_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000005589 142.0
SX2_k127_2341815_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000001567 140.0
SX2_k127_2347047_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 4.128e-217 678.0
SX2_k127_2347047_1 Protein of unknown function, DUF - - - 0.00000000000000000000000000000000000000000000007608 174.0
SX2_k127_2347047_2 GIY-YIG type nucleases (URI domain) K07461 - - 0.00000004994 65.0
SX2_k127_2347047_3 O-methyltransferase - - - 0.0000001525 54.0
SX2_k127_2371161_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 390.0
SX2_k127_2371161_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000006212 219.0
SX2_k127_2371161_2 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000001851 191.0
SX2_k127_2371161_3 - - - - 0.00000000000001291 80.0
SX2_k127_2371161_4 - - - - 0.0000000000007074 76.0
SX2_k127_2386589_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 481.0
SX2_k127_2386589_1 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000001335 241.0
SX2_k127_2386589_2 PFAM MazG nucleotide pyrophosphohydrolase K04765 - 3.6.1.9 0.0000000000000000000000000000000000000001424 155.0
SX2_k127_2390310_0 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 299.0
SX2_k127_2390310_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000004095 146.0
SX2_k127_2390780_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1369.0
SX2_k127_2394530_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 2.511e-230 736.0
SX2_k127_2400844_0 Ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003253 270.0
SX2_k127_2400844_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001862 267.0
SX2_k127_2400844_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001608 229.0
SX2_k127_2400844_3 - - - - 0.0000000000000000005342 88.0
SX2_k127_2400844_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000008059 70.0
SX2_k127_2408836_0 General function prediction only K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000865 255.0
SX2_k127_2408836_1 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000025 209.0
SX2_k127_2418625_0 Phosphoenolpyruvate carboxylase K01595 - 4.1.1.31 1.309e-254 804.0
SX2_k127_2418625_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000003766 170.0
SX2_k127_2444278_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 527.0
SX2_k127_2444278_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 471.0
SX2_k127_2466683_0 serine threonine protein kinase K11912 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000004171 204.0
SX2_k127_2466683_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000009649 164.0
SX2_k127_2477842_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 587.0
SX2_k127_2477842_1 ATPase (AAA K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 411.0
SX2_k127_2477842_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000000000000000238 159.0
SX2_k127_2477842_3 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000002125 115.0
SX2_k127_249215_0 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000002328 225.0
SX2_k127_249215_1 Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000007135 153.0
SX2_k127_249215_2 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000002384 100.0
SX2_k127_249215_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000001546 85.0
SX2_k127_2493028_0 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 367.0
SX2_k127_2493028_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000009539 119.0
SX2_k127_2493028_2 Domain of unknown function (DUF4124) - - - 0.000002436 52.0
SX2_k127_2554398_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 313.0
SX2_k127_2554398_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000004461 184.0
SX2_k127_2567398_0 BT1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 594.0
SX2_k127_2567398_1 PFAM Endonuclease exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 295.0
SX2_k127_2567398_2 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000004702 181.0
SX2_k127_2567398_3 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000002051 117.0
SX2_k127_2569559_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 596.0
SX2_k127_2569559_1 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 519.0
SX2_k127_2569559_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 381.0
SX2_k127_2570764_0 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 387.0
SX2_k127_2570764_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000001064 181.0
SX2_k127_2570764_2 AAA domain K07028 - - 0.000000000000000000000000000000000000000000001085 175.0
SX2_k127_2570764_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298 - - 0.00000000000000000000000000000000000482 142.0
SX2_k127_2570764_4 Conserved TM helix - - - 0.00000000000000000000000000000000001454 146.0
SX2_k127_2570764_5 MgtE intracellular N domain - - - 0.00000000000000000000000007349 120.0
SX2_k127_2570764_6 Protein required for attachment to host cells - - - 0.00000003237 58.0
SX2_k127_2570764_7 Protein required for attachment to host cells - - - 0.00004872 46.0
SX2_k127_2571030_0 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 328.0
SX2_k127_2571030_1 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000007369 201.0
SX2_k127_2571030_2 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000006051 123.0
SX2_k127_2571030_3 Protein of unknown function (DUF3034) - - - 0.000000000000000008036 94.0
SX2_k127_2571030_4 chemotaxis sensory transducer K03406,K03776,K05874,K05875 - - 0.0000000000001278 78.0
SX2_k127_2571048_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 588.0
SX2_k127_2571048_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 431.0
SX2_k127_2571048_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000001318 72.0
SX2_k127_2607651_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.61e-220 697.0
SX2_k127_2607651_1 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000002987 207.0
SX2_k127_2607651_2 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.000000000000000000000000000000002639 133.0
SX2_k127_2607651_3 Phosphotransferase System K11189 - - 0.00000000000000000000000001185 111.0
SX2_k127_2609954_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 480.0
SX2_k127_2609954_1 TIGRFAM TIGR00645 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001626 226.0
SX2_k127_2609954_2 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000002363 207.0
SX2_k127_2612134_0 Catalyzes the formation of 2-oxoglutarate from isocitrate K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 471.0
SX2_k127_2612134_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0008535 47.0
SX2_k127_2618526_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 496.0
SX2_k127_2618526_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 332.0
SX2_k127_2618526_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059,K03793 - 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000004586 265.0
SX2_k127_2618526_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000007724 215.0
SX2_k127_2618526_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000004353 179.0
SX2_k127_2618526_5 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000007854 175.0
SX2_k127_2618526_6 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000006182 162.0
SX2_k127_2618526_7 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000005354 106.0
SX2_k127_2618526_8 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.0000000001235 63.0
SX2_k127_2618526_9 - - - - 0.0000004031 58.0
SX2_k127_2657015_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015673,GO:0015679,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0031224,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0071944,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1902601,GO:1990169 - 0.0 1304.0
SX2_k127_2657015_1 short-chain dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 360.0
SX2_k127_2657015_2 Protein of unknown function, DUF484 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002305 287.0
SX2_k127_2657015_3 CRS1_YhbY K07574 - - 0.0000000000000000000000000002706 116.0
SX2_k127_2664528_0 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 386.0
SX2_k127_2664528_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003445 281.0
SX2_k127_2664528_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005369 256.0
SX2_k127_2674854_0 Ethylbenzene dehydrogenase - - - 0.0000000000005376 81.0
SX2_k127_2679511_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 475.0
SX2_k127_2679511_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 462.0
SX2_k127_2679511_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000008324 199.0
SX2_k127_2679511_3 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000000000000000008697 199.0
SX2_k127_2679511_4 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000007075 166.0
SX2_k127_2679511_5 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000002538 168.0
SX2_k127_2679511_6 Cytochrome c mono- and diheme variants - - - 0.000000000000000000002857 101.0
SX2_k127_2701772_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 517.0
SX2_k127_2701772_1 Peptidase dimerisation domain - - - 0.00000000000002292 72.0
SX2_k127_2704965_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002126 259.0
SX2_k127_2707254_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 4.904e-249 774.0
SX2_k127_2707254_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 553.0
SX2_k127_2707254_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 537.0
SX2_k127_2707254_3 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001779 270.0
SX2_k127_2707254_4 signal transduction histidine kinase K07708 - 2.7.13.3 0.000000000000000000000000001299 117.0
SX2_k127_2707254_5 Domain of unknown function (DUF4124) - - - 0.00000000000000004817 89.0
SX2_k127_2727300_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00651 - 2.3.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 539.0
SX2_k127_2727300_1 (ABC) transporter - - - 0.00000002045 55.0
SX2_k127_2737620_0 Sulfotransferase domain K01014 - 2.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 522.0
SX2_k127_2737620_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 503.0
SX2_k127_2737620_2 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 318.0
SX2_k127_2743874_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000001698 248.0
SX2_k127_2743874_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000003785 212.0
SX2_k127_2743874_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000004402 90.0
SX2_k127_2743874_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000005096 55.0
SX2_k127_2748997_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 1.283e-288 895.0
SX2_k127_2750689_0 formylmethanofuran dehydrogenase activity K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000002172 244.0
SX2_k127_2750689_1 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000009389 143.0
SX2_k127_2750689_2 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 - 2.3.1.101 0.000000000000000000000000000001357 123.0
SX2_k127_2759078_0 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000003337 234.0
SX2_k127_2759078_1 histone deacetylase - - - 0.000000000000000000000000000000000000000000002394 171.0
SX2_k127_2759580_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 4.405e-219 701.0
SX2_k127_2759812_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001757 285.0
SX2_k127_2759812_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001272 263.0
SX2_k127_2759812_2 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000001206 170.0
SX2_k127_2759812_3 Belongs to the UPF0235 family K09131 - - 0.00000000002342 68.0
SX2_k127_2814695_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 354.0
SX2_k127_2814695_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000294 248.0
SX2_k127_2814695_2 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000001907 104.0
SX2_k127_2816571_0 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 379.0
SX2_k127_2816571_1 Radical SAM domain - - - 0.000000000000000005171 85.0
SX2_k127_2816571_2 PFAM Toluene tolerance K07323 - - 0.00000000000000004156 85.0
SX2_k127_2825133_0 PFAM Methylene-tetrahydromethanopterin dehydrogenase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 393.0
SX2_k127_2825133_1 Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001345 256.0
SX2_k127_2825133_2 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000000000000001138 221.0
SX2_k127_2825133_3 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 0.000000000000000000000002153 103.0
SX2_k127_2825133_4 AAA domain K03112 - - 0.000000001526 70.0
SX2_k127_2825315_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 526.0
SX2_k127_2825315_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 303.0
SX2_k127_283582_0 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 415.0
SX2_k127_283582_1 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 417.0
SX2_k127_2837329_0 TIGRFAM periplasmic protein thiol K02199 - - 0.00000000000000000000000000000000000000000000000000000000000002124 219.0
SX2_k127_2837329_1 Cytochrome c-type biogenesis protein K02198 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000005194 176.0
SX2_k127_2837329_2 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000002705 161.0
SX2_k127_2837329_3 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000002872 146.0
SX2_k127_283772_0 Glycosyl transferases group 1 K12995 - 2.4.1.348 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 380.0
SX2_k127_283772_1 epimerase dehydratase - - - 0.000000000000000000000000000001347 126.0
SX2_k127_2846656_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 466.0
SX2_k127_2846656_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001612 246.0
SX2_k127_2849815_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.983e-220 685.0
SX2_k127_2849815_1 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 407.0
SX2_k127_2849815_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002643 243.0
SX2_k127_2851664_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 327.0
SX2_k127_2851664_1 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000001258 118.0
SX2_k127_2851664_2 antisigma factor binding K03409,K05946 - 2.4.1.187 0.000000004266 64.0
SX2_k127_2870824_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 384.0
SX2_k127_2870824_1 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000005387 179.0
SX2_k127_2877113_0 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003595 240.0
SX2_k127_2881540_0 chemotaxis, protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 356.0
SX2_k127_2881540_1 CheW-like domain - - - 0.00000000000004975 76.0
SX2_k127_2881540_2 Two component signalling adaptor domain - - - 0.00001194 57.0
SX2_k127_2897806_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 7.891e-219 686.0
SX2_k127_2897806_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005315 265.0
SX2_k127_2897806_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000001113 240.0
SX2_k127_2897806_3 Putative molybdenum carrier - - - 0.00000000000000000000000000000000000000000005326 164.0
SX2_k127_2897806_4 Protein conserved in bacteria - - - 0.00000000000000000000000000002471 119.0
SX2_k127_2897806_5 Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase K07740 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000000000000000000000003078 110.0
SX2_k127_2899025_0 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 353.0
SX2_k127_2899025_1 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008654 272.0
SX2_k127_2899025_2 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000005372 166.0
SX2_k127_2899025_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.000002397 56.0
SX2_k127_2923699_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 1.525e-294 923.0
SX2_k127_2923699_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 8.721e-252 779.0
SX2_k127_2923699_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 8.011e-215 673.0
SX2_k127_2923699_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 487.0
SX2_k127_2923699_4 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000007634 252.0
SX2_k127_2924572_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 432.0
SX2_k127_2924572_1 TraB family K09973 - - 0.0000000000000000000000000000003504 134.0
SX2_k127_2924572_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000003326 111.0
SX2_k127_2937208_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 404.0
SX2_k127_2937208_1 Belongs to the UPF0176 family K07146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 331.0
SX2_k127_2937208_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K01802,K03769 - 5.2.1.8 0.0000000000000000000000000000000000000004066 150.0
SX2_k127_2937208_3 Transposase IS200 like K07491 - - 0.0000000000000002534 78.0
SX2_k127_2942486_0 Type II secretion system (T2SS), protein F K02455,K12278 - - 0.000000000000000000000000000000000000000000000000004199 184.0
SX2_k127_2942486_1 general secretion pathway protein - - - 0.00000000000000000000000001143 116.0
SX2_k127_2942486_2 O-Antigen ligase - - - 0.00000000000000000000000002413 121.0
SX2_k127_2942486_3 Prokaryotic N-terminal methylation motif K10924 - - 0.0000000000000000000003648 101.0
SX2_k127_2952910_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 286.0
SX2_k127_2952910_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000946 216.0
SX2_k127_2952910_2 Methyltransferase - - - 0.00000000000000000000000000000000000000000000002042 179.0
SX2_k127_2973371_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 3.381e-218 692.0
SX2_k127_2973371_1 PFAM pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000002111 193.0
SX2_k127_2973371_2 Two component signalling adaptor domain - - - 0.00000000000000000000000000000000000000000000000001065 184.0
SX2_k127_2992117_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000004824 231.0
SX2_k127_2992117_1 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000002362 162.0
SX2_k127_3019300_0 Sigma factor PP2C-like phosphatases K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 454.0
SX2_k127_3019300_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 327.0
SX2_k127_3019300_2 Anti-sigma-factor antagonist K04749 - - 0.0000000000000000000000000003105 117.0
SX2_k127_3019300_3 Permease MlaE K02066 - - 0.00003569 49.0
SX2_k127_3025368_0 COG1076 DnaJ-domain-containing proteins 1 K05801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 292.0
SX2_k127_3025368_1 - - - - 0.00000000000000000000104 94.0
SX2_k127_3025368_2 PilZ domain - - - 0.0004237 48.0
SX2_k127_3035922_0 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 321.0
SX2_k127_3035922_1 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000001843 239.0
SX2_k127_3035922_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000002319 182.0
SX2_k127_3035922_3 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.000000000005044 69.0
SX2_k127_3036747_0 FAD dependent oxidoreductase - - - 1.254e-214 673.0
SX2_k127_3036747_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 290.0
SX2_k127_3036747_2 - - - - 0.0000000000000000000000000000000000000000003529 165.0
SX2_k127_3061879_0 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 431.0
SX2_k127_3061879_1 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000005008 183.0
SX2_k127_3061879_2 COG0424 Nucleotide-binding protein implicated in inhibition of septum formation K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.0000000000000000000000000000000000000000000000003683 181.0
SX2_k127_3068735_0 COG0501 Zn-dependent protease with chaperone function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004299 269.0
SX2_k127_3068735_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
SX2_k127_3088712_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.392e-206 647.0
SX2_k127_3088712_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 319.0
SX2_k127_309808_0 ABC transporter K06020 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 1.885e-285 884.0
SX2_k127_309808_1 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000526 184.0
SX2_k127_309808_2 HD domain K07814 - - 0.00000000000000000000000000000000000000008785 153.0
SX2_k127_3104678_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000001122 219.0
SX2_k127_3104678_1 - - - - 0.00000000000006824 75.0
SX2_k127_3129315_0 C-terminal region of aryl-sulfatase K01130 - 3.1.6.1 8.082e-212 672.0
SX2_k127_3129315_1 Iron-sulfur cluster-binding domain K06871 - - 3.465e-208 655.0
SX2_k127_3129315_2 Pfam Sulfatase K01130 - 3.1.6.1 0.000000000000000005032 87.0
SX2_k127_3137554_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 1.304e-194 614.0
SX2_k127_3137554_1 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 293.0
SX2_k127_3137554_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000005336 134.0
SX2_k127_3138927_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 4.575e-302 933.0
SX2_k127_3138927_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 322.0
SX2_k127_3138927_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001835 270.0
SX2_k127_3138927_3 COG0440 Acetolactate synthase, small (regulatory) subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000009206 233.0
SX2_k127_3138927_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000008358 147.0
SX2_k127_3165524_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2181.0
SX2_k127_3165524_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1669.0
SX2_k127_3165524_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1153.0
SX2_k127_3165524_3 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.88e-223 695.0
SX2_k127_3165524_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004213 224.0
SX2_k127_3165524_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000002054 224.0
SX2_k127_3175541_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1161.0
SX2_k127_3175541_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 384.0
SX2_k127_3175541_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 341.0
SX2_k127_3175541_3 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000006107 108.0
SX2_k127_3175541_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000003283 89.0
SX2_k127_3191677_0 catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids K00835 - 2.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 531.0
SX2_k127_3191677_1 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 461.0
SX2_k127_3191677_2 - - - - 0.000000000000000000005489 104.0
SX2_k127_3192241_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001267 284.0
SX2_k127_3192241_1 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000001794 211.0
SX2_k127_3192241_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000001377 144.0
SX2_k127_3213100_0 Predicted membrane protein (DUF2339) - - - 7.66e-227 731.0
SX2_k127_3213100_1 PFAM chemotaxis K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 310.0
SX2_k127_3213100_2 Protein of unknown function (DUF3999) - - - 0.000000000000000000000000000000000000000000000000000000000000000001314 244.0
SX2_k127_3213100_3 17 kDa outer membrane surface antigen - - - 0.0000000000000000000000000000000000000000000000000003149 189.0
SX2_k127_3215740_0 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 377.0
SX2_k127_3223849_0 DNA polymerase III, alpha subunit K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000001488 186.0
SX2_k127_3223849_1 general secretion pathway protein D K02453 - - 0.00000000000000000000000000000000000000000009813 171.0
SX2_k127_3223849_2 Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time K02337 - 2.7.7.7 0.0000000000000000000000000000000000002706 143.0
SX2_k127_3223849_3 General secretion pathway protein C K02452 - - 0.0000000000000000000000000004422 124.0
SX2_k127_3234706_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 387.0
SX2_k127_3234706_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000001439 63.0
SX2_k127_3245628_0 PFAM Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 583.0
SX2_k127_3245628_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 308.0
SX2_k127_3245628_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000008314 242.0
SX2_k127_3245628_3 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000006264 192.0
SX2_k127_3246019_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 360.0
SX2_k127_3246019_1 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 321.0
SX2_k127_3268003_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 5.638e-208 655.0
SX2_k127_3268003_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 425.0
SX2_k127_3268003_2 COG0512 Anthranilate para-aminobenzoate synthases component II K01658,K01664 GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 316.0
SX2_k127_3273696_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 8.515e-202 646.0
SX2_k127_3273696_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000006225 197.0
SX2_k127_3273696_2 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.00000000000000000000006806 102.0
SX2_k127_3285295_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.358e-210 661.0
SX2_k127_3285295_1 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 461.0
SX2_k127_3285295_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 443.0
SX2_k127_3285295_3 Mg2 and Co2 transporter CorC K06189 GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 323.0
SX2_k127_3285295_4 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 329.0
SX2_k127_3285295_5 Conserved TM helix K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 311.0
SX2_k127_3285295_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005228 262.0
SX2_k127_3285295_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000009621 173.0
SX2_k127_3285295_8 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.0000000000000000000000000000000000004565 141.0
SX2_k127_3287802_0 Cytosol aminopeptidase family, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 462.0
SX2_k127_3287802_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 342.0
SX2_k127_3287802_2 RNA-binding protein - - - 0.0000000000000000000002871 102.0
SX2_k127_3316317_0 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003863 277.0
SX2_k127_3316317_1 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001772 261.0
SX2_k127_3332198_0 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 308.0
SX2_k127_3332198_1 COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II) K04568 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000002044 213.0
SX2_k127_3332198_2 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843,K19810 - 5.4.3.2 0.00000000000000000000000000000000000000000000002891 173.0
SX2_k127_3347991_0 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 503.0
SX2_k127_3347991_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000001924 169.0
SX2_k127_3351985_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 426.0
SX2_k127_3351985_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 328.0
SX2_k127_3361294_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 8.833e-211 661.0
SX2_k127_3361294_1 Trypsin K04691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 351.0
SX2_k127_3361294_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000079 257.0
SX2_k127_3361294_3 Cytochrome C1 K00413 - - 0.00000000000000000000000000001247 130.0
SX2_k127_3396944_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 376.0
SX2_k127_3396944_1 PFAM Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 310.0
SX2_k127_3400185_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 456.0
SX2_k127_3400185_1 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions K05501 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000004274 236.0
SX2_k127_3400185_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000008872 234.0
SX2_k127_3400185_3 Pfam Transposase IS66 - - - 0.0000000000000000000000001187 114.0
SX2_k127_3406969_0 PFAM Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 414.0
SX2_k127_3406969_1 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 359.0
SX2_k127_3446447_0 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000003667 224.0
SX2_k127_3446447_1 - - - - 0.000000000000000000000000000000002612 135.0
SX2_k127_3461220_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 403.0
SX2_k127_3461220_1 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000001437 189.0
SX2_k127_3461220_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000000006732 147.0
SX2_k127_3461220_3 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000002048 86.0
SX2_k127_3463222_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 292.0
SX2_k127_3463222_1 Superoxide dismutase K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002205 267.0
SX2_k127_3463222_2 ORF6N domain - - - 0.000000000000000000000000000000000000000000000000000006991 195.0
SX2_k127_3463222_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000003173 176.0
SX2_k127_3463222_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000135 167.0
SX2_k127_3466513_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 1.386e-287 892.0
SX2_k127_3466513_1 Dodecin K09165 - - 0.00000000000000000000002654 100.0
SX2_k127_3467857_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.785e-320 992.0
SX2_k127_3485061_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 5.686e-217 678.0
SX2_k127_3485061_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 367.0
SX2_k127_3485061_2 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000001038 235.0
SX2_k127_3485061_3 Protein of unknown function (DUF3426) - - - 0.00000000003627 73.0
SX2_k127_3523784_0 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000007441 238.0
SX2_k127_3523784_1 PFAM Gram-negative bacterial tonB protein K03832 - - 0.000000000000000000000000000000000000000000009332 171.0
SX2_k127_3523784_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000001235 149.0
SX2_k127_3544684_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 541.0
SX2_k127_3544684_1 protein conserved in bacteria K09948 - - 0.00000000000000000000000000000001415 133.0
SX2_k127_3557680_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001585 265.0
SX2_k127_3557680_1 - - - - 0.0000000000000000000000000000000000000000002085 167.0
SX2_k127_3557680_2 ribonuclease activity - - - 0.0000000001055 65.0
SX2_k127_357770_0 Hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 331.0
SX2_k127_357770_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 342.0
SX2_k127_357770_2 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000000001575 178.0
SX2_k127_357770_3 DNA polymerase III, delta' K02341 - 2.7.7.7 0.0000000000007618 75.0
SX2_k127_3588384_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.519e-241 750.0
SX2_k127_3588384_1 cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.00000000000000000000000000000000000000000000000015 184.0
SX2_k127_3594864_0 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 524.0
SX2_k127_3594864_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 285.0
SX2_k127_3604123_0 lytic transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 365.0
SX2_k127_3604123_1 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001422 238.0
SX2_k127_3612690_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000003501 277.0
SX2_k127_3612690_2 PFAM LppC K07121 - - 0.0000007311 57.0
SX2_k127_3622724_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 389.0
SX2_k127_3622724_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 290.0
SX2_k127_3622724_2 Glutaredoxin-like domain (DUF836) - - - 0.0000000000003197 72.0
SX2_k127_363926_0 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 362.0
SX2_k127_363926_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000001936 158.0
SX2_k127_363926_2 MazG-like family - - - 0.000000000000000000000000000000000000004248 148.0
SX2_k127_363926_3 Putative diguanylate phosphodiesterase - - - 0.0000000001112 64.0
SX2_k127_3652153_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 523.0
SX2_k127_3652153_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 493.0
SX2_k127_3652153_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 362.0
SX2_k127_3652153_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000000000000000004277 155.0
SX2_k127_3654965_0 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 381.0
SX2_k127_3654965_1 oxidase, assembly K02258 - - 0.0000000000000000000000000000000000000000000006088 173.0
SX2_k127_3654965_2 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.00000000000000000000000000000002458 128.0
SX2_k127_3654965_3 signal sequence binding - - - 0.000000000000000000000003604 110.0
SX2_k127_3654965_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.00000000000000001106 83.0
SX2_k127_3654965_5 Protein of unknown function (DUF2909) - - - 0.000000713 53.0
SX2_k127_368816_0 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 489.0
SX2_k127_368816_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000001014 119.0
SX2_k127_3739125_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005862 279.0
SX2_k127_3739125_1 chemotaxis protein K03406 - - 0.0000001493 54.0
SX2_k127_3754429_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.659e-258 804.0
SX2_k127_3754429_1 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 297.0
SX2_k127_3754429_2 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000001383 200.0
SX2_k127_3754429_3 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.00000000000000000000000000000000003773 136.0
SX2_k127_3761160_0 metal-dependent phosphoesterases (PHP family) K07053 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 313.0
SX2_k127_3761160_1 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002821 282.0
SX2_k127_3769582_0 TonB-dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000331 149.0
SX2_k127_3769582_1 AsmA family K07289,K07290 - - 0.00000000000000000000000000004079 124.0
SX2_k127_3790062_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 487.0
SX2_k127_3790062_1 HAD-superfamily hydrolase subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000001309 224.0
SX2_k127_3790062_2 Belongs to the peptidase S1C family K04772 - - 0.0000000000000000000000000000001708 127.0
SX2_k127_3790062_3 Radical SAM - - - 0.00000000000004975 76.0
SX2_k127_3800962_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 512.0
SX2_k127_3800962_1 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000002384 265.0
SX2_k127_3800962_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000139 212.0
SX2_k127_3800962_3 Glycyl-tRNA synthetase beta subunit K01879 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000000000000000000000000000000001428 173.0
SX2_k127_3830443_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 450.0
SX2_k127_3830443_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000003146 239.0
SX2_k127_3830443_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000004274 199.0
SX2_k127_3830443_3 TIGRFAM Glutaredoxin-like protein, YruB-family - - - 0.000001617 57.0
SX2_k127_3837410_0 TonB dependent receptor - - - 1.229e-224 713.0
SX2_k127_3837410_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000001223 205.0
SX2_k127_3855270_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 517.0
SX2_k127_3855270_1 - - - - 0.000000000000000000000000000000001948 138.0
SX2_k127_3855270_2 Domain of unknown function (DUF4404) - - - 0.000000000000007306 78.0
SX2_k127_3860588_0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00210,K00220,K00800 - 1.3.1.12,1.3.1.43,2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 494.0
SX2_k127_3860588_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 469.0
SX2_k127_3860588_2 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 319.0
SX2_k127_3887097_0 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000007206 216.0
SX2_k127_3887097_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000000000000000000001137 173.0
SX2_k127_3888071_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 341.0
SX2_k127_3888071_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000044 220.0
SX2_k127_3913832_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.172e-203 635.0
SX2_k127_3913832_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 403.0
SX2_k127_3913832_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 334.0
SX2_k127_3916066_0 acyl-coa dehydrogenase - - - 2.549e-266 824.0
SX2_k127_3916066_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 543.0
SX2_k127_3916075_0 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 301.0
SX2_k127_3916075_1 Protein of unknown function (DUF4065) - - - 0.0000000000000000000000000000000000000000000000009869 180.0
SX2_k127_3916075_2 transcription regulator containing HTH domain K18831 - - 0.0000000000000000000000000000000000000000000004097 169.0
SX2_k127_3916075_3 protein conserved in bacteria K19166 - - 0.000000000000000000000000000000000005926 138.0
SX2_k127_39311_0 Putative transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009769 274.0
SX2_k127_39311_1 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003057 275.0
SX2_k127_39311_2 Belongs to the 'phage' integrase family - - - 0.00000000001631 66.0
SX2_k127_3935763_0 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 330.0
SX2_k127_3935763_1 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000005752 247.0
SX2_k127_3935763_2 pfam ammecr1 - - - 0.0000000000000000000000000000000007828 135.0
SX2_k127_3948440_0 Cupin domain - - - 0.000000000000000000000000000000000000000007585 158.0
SX2_k127_3948440_1 GAF domain K07673 - 2.7.13.3 0.0000000000000000000000001369 118.0
SX2_k127_3965448_0 Involved in initiation control of chromosome replication - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 421.0
SX2_k127_3965448_1 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000005634 229.0
SX2_k127_3965830_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.029e-261 810.0
SX2_k127_3971934_0 lipoprotein K07121 GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 321.0
SX2_k127_3971934_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271,K12961 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001299 270.0
SX2_k127_3971934_2 PFAM transport-associated - - - 0.0000000000000000000000000000000000000000000000000002485 191.0
SX2_k127_3971934_3 copG family - - - 0.0000000000000000000000000002049 116.0
SX2_k127_3971934_4 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000118 116.0
SX2_k127_39798_0 Belongs to the glutamate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 606.0
SX2_k127_39798_1 endonuclease containing a URI domain K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000002155 78.0
SX2_k127_3988182_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 312.0
SX2_k127_3988182_1 Biopolymer transport protein K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000001674 168.0
SX2_k127_3988182_2 TonB C terminal K03646 - - 0.0000000001117 73.0
SX2_k127_3989870_0 Efflux pump membrane transporter K03296 - - 0.0 1110.0
SX2_k127_3989870_1 Helix-turn-helix domain - - - 0.0000000000000003506 83.0
SX2_k127_3993652_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.484e-199 629.0
SX2_k127_3993652_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000764 226.0
SX2_k127_3996942_0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000003093 237.0
SX2_k127_3996942_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000001888 217.0
SX2_k127_3996942_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000003624 176.0
SX2_k127_3996942_3 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002261 144.0
SX2_k127_4020041_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 456.0
SX2_k127_4020041_1 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 413.0
SX2_k127_4020041_2 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000002272 186.0
SX2_k127_4020041_3 Belongs to the Nudix hydrolase family. NudJ subfamily K03574,K12152 GO:0003674,GO:0003824,GO:0004787,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0017111 3.6.1.55 0.0000000000000000000000000000000000000000000000001538 181.0
SX2_k127_4048693_0 serine threonine protein kinase K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 317.0
SX2_k127_4048693_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008351 244.0
SX2_k127_4048806_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000003651 72.0
SX2_k127_4054146_0 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000004613 247.0
SX2_k127_4054146_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000101 201.0
SX2_k127_4054146_2 Belongs to the HSP15 family K04762 - - 0.000000000000000000000000002442 119.0
SX2_k127_4058522_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 502.0
SX2_k127_4058522_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 424.0
SX2_k127_4058522_2 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 362.0
SX2_k127_4058522_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000009423 218.0
SX2_k127_4058522_4 subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000006382 216.0
SX2_k127_4058522_5 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000001317 157.0
SX2_k127_4058522_6 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000003592 108.0
SX2_k127_4058522_7 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000009118 95.0
SX2_k127_4058522_8 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000001051 96.0
SX2_k127_4065028_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 564.0
SX2_k127_4065028_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000001628 252.0
SX2_k127_4065028_2 PFAM Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000000000000000000001059 212.0
SX2_k127_4065028_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000004352 198.0
SX2_k127_4065028_4 Thioredoxin-like - - - 0.0000000000001122 73.0
SX2_k127_4104480_0 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000006515 191.0
SX2_k127_4104480_1 Catalyzes the conversion of dihydroorotate to orotate K00254 - 1.3.5.2 0.0000000000000000002311 92.0
SX2_k127_4115056_0 ethanolamine - - - 9.564e-234 729.0
SX2_k127_4115056_1 - - - - 0.0000000000003766 71.0
SX2_k127_4115056_2 - - - - 0.000001426 51.0
SX2_k127_4128366_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 611.0
SX2_k127_4128366_1 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 328.0
SX2_k127_4128366_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000001178 173.0
SX2_k127_4128366_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000001149 151.0
SX2_k127_4168776_0 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000002159 116.0
SX2_k127_4170647_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 1.659e-288 896.0
SX2_k127_4198059_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 4.969e-204 646.0
SX2_k127_4198059_1 Belongs to the dihydroorotate dehydrogenase family K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 503.0
SX2_k127_4198059_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 343.0
SX2_k127_4198059_3 PFAM Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001445 271.0
SX2_k127_4198059_4 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000001621 220.0
SX2_k127_4198059_5 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000786 168.0
SX2_k127_4198059_6 PFAM Rhodanese-like - - - 0.000000000000000000000000000505 118.0
SX2_k127_4198178_0 - K09771 - - 0.00000000000000000000000000000000002338 137.0
SX2_k127_4198178_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000009072 93.0
SX2_k127_4200580_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 591.0
SX2_k127_4200580_1 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 415.0
SX2_k127_4200580_2 TIGRFAM FeS assembly SUF system protein SufT - - - 0.000000000000000000000000000000000000000000000000000000000000006019 220.0
SX2_k127_4200580_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000737 202.0
SX2_k127_4220935_0 Poly-beta-hydroxybutyrate polymerase K03821 - - 3.79e-221 695.0
SX2_k127_427127_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 494.0
SX2_k127_427127_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 359.0
SX2_k127_427127_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 317.0
SX2_k127_427127_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000006663 223.0
SX2_k127_427127_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000008042 185.0
SX2_k127_427127_5 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000701 146.0
SX2_k127_427127_6 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001418 73.0
SX2_k127_4279425_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001248 248.0
SX2_k127_4279425_1 Domain of unknown function (DUF4440) - - - 0.0000000001321 67.0
SX2_k127_4279425_2 BetI-type transcriptional repressor, C-terminal - - - 0.00000002471 63.0
SX2_k127_4280754_0 FKBP-type peptidyl-prolyl isomerase K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000004248 238.0
SX2_k127_4280754_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000003951 215.0
SX2_k127_4280754_2 Tetratricopeptide repeat - - - 0.00000000000000000005142 96.0
SX2_k127_4280754_3 Acyltransferase family - - - 0.0000000007173 67.0
SX2_k127_4286775_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 1.266e-206 655.0
SX2_k127_4286775_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 306.0
SX2_k127_4286775_2 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000001236 151.0
SX2_k127_4294006_0 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 338.0
SX2_k127_4294006_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000006681 236.0
SX2_k127_4294006_2 signal sequence binding - - - 0.00000000000000000007099 94.0
SX2_k127_4300766_0 O-Antigen ligase - - - 0.0000000000001176 84.0
SX2_k127_4300766_1 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000000002217 74.0
SX2_k127_4327181_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 332.0
SX2_k127_4327181_1 anaerobic respiration - - - 0.000000000000000000000001299 112.0
SX2_k127_4328985_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.433e-246 771.0
SX2_k127_4328985_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000006666 173.0
SX2_k127_4329104_0 Peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 477.0
SX2_k127_4329104_1 lipid carrier protein - - - 0.0000000000000000000000000000000000000001709 156.0
SX2_k127_4329104_2 Peptidase family U32 - - - 0.00005159 46.0
SX2_k127_433080_0 electron transfer flavoprotein beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 339.0
SX2_k127_433080_1 lyase activity - - - 0.00000000000000000000000000000000000000000000000000004362 202.0
SX2_k127_4331000_0 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001556 218.0
SX2_k127_4331000_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000002679 154.0
SX2_k127_4331000_2 - - - - 0.0000000000000000000000000000000000004706 145.0
SX2_k127_4331000_3 4Fe-4S single cluster domain - - - 0.000000000000000000004894 94.0
SX2_k127_4332900_0 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 528.0
SX2_k127_4370366_0 Transport of potassium into the cell K03549 - - 0.00000000000000000000000000000000000000000000000000000000000000005319 226.0
SX2_k127_4370366_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000001253 197.0
SX2_k127_4370366_2 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.00000000000000000000000000000000000000004333 160.0
SX2_k127_4374659_0 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 3.512e-217 686.0
SX2_k127_4409624_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 584.0
SX2_k127_4409624_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 308.0
SX2_k127_4409624_2 Membrane K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 287.0
SX2_k127_4409624_3 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.000000000000000000000000000000000000000000000000000000000004872 216.0
SX2_k127_4409624_4 Sel1-like repeats. K07126 - - 0.0000000000000003752 86.0
SX2_k127_4413344_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000967 514.0
SX2_k127_4413344_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000844 76.0
SX2_k127_4416283_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 514.0
SX2_k127_4416283_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 455.0
SX2_k127_4416283_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001723 236.0
SX2_k127_4416283_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000002738 232.0
SX2_k127_4416283_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000004282 217.0
SX2_k127_4416283_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000001885 126.0
SX2_k127_4419700_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 5.086e-205 644.0
SX2_k127_4419700_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus - - - 2.269e-202 646.0
SX2_k127_4419700_2 synthase component I K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 533.0
SX2_k127_4419700_3 PFAM aspartate glutamate uridylate kinase - - - 0.0000000000000000000000000000000000002057 149.0
SX2_k127_4419700_4 cheY-homologous receiver domain - - - 0.000000000000000000000007388 108.0
SX2_k127_4422272_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 420.0
SX2_k127_4422272_1 TraB family K09973 - - 0.00000000000000000000000000000404 128.0
SX2_k127_4429370_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 450.0
SX2_k127_4429370_1 COG2041 Sulfite oxidase and related enzymes K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 444.0
SX2_k127_4429370_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 330.0
SX2_k127_4432007_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 467.0
SX2_k127_4432007_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 327.0
SX2_k127_4432007_2 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000001794 66.0
SX2_k127_4436609_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000009383 221.0
SX2_k127_4436609_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000003277 183.0
SX2_k127_4436609_2 PAS fold - - - 0.00000000000000000000000000000004421 131.0
SX2_k127_4443470_0 GTP-binding protein K06207 - - 1.715e-246 776.0
SX2_k127_4443470_1 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000002828 84.0
SX2_k127_4454369_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 541.0
SX2_k127_4454369_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 434.0
SX2_k127_4454369_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0001479 46.0
SX2_k127_4464877_0 response regulator K02481,K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 527.0
SX2_k127_4464877_1 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 416.0
SX2_k127_4464877_2 Signal transduction histidine kinase K02668 - 2.7.13.3 0.00000000000000000000000000000000001027 140.0
SX2_k127_4464877_3 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000001567 134.0
SX2_k127_4464877_4 Protein of unknown function (DUF2723) - - - 0.000000000000000001545 94.0
SX2_k127_4466451_0 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001975 277.0
SX2_k127_4466451_1 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000001432 115.0
SX2_k127_4466451_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000106 75.0
SX2_k127_4467917_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.445e-252 781.0
SX2_k127_4467917_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000001446 184.0
SX2_k127_4518851_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 404.0
SX2_k127_4518851_1 Belongs to the UPF0176 family K07146 - - 0.000000000000000000000000000753 114.0
SX2_k127_453078_0 response regulator receiver K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 291.0
SX2_k127_453078_1 PFAM Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000001298 182.0
SX2_k127_453078_2 COG0457 FOG TPR repeat - - - 0.00000000000000000005365 91.0
SX2_k127_4548326_0 polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000001122 214.0
SX2_k127_4548326_1 Protein conserved in bacteria - - - 0.000000000000000001999 96.0
SX2_k127_4557944_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 582.0
SX2_k127_4557944_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000009446 204.0
SX2_k127_4557944_2 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.000000000000000000000000000000000005204 146.0
SX2_k127_4557944_3 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000003115 119.0
SX2_k127_4557944_4 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000891 115.0
SX2_k127_4562606_0 pfam abc-3 K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 305.0
SX2_k127_4562606_1 PFAM ABC transporter related K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004042 278.0
SX2_k127_4565740_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 577.0
SX2_k127_4565740_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 443.0
SX2_k127_4565740_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 349.0
SX2_k127_4565740_3 serine threonine protein kinase K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 319.0
SX2_k127_4565740_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000009358 218.0
SX2_k127_4570785_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.022e-244 766.0
SX2_k127_4570785_1 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001244 235.0
SX2_k127_4570785_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000001863 88.0
SX2_k127_4571406_0 COG1064 Zn-dependent alcohol K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 539.0
SX2_k127_4571406_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 527.0
SX2_k127_4571406_2 protein conserved in bacteria containing a divergent form of TPR repeats - - - 0.00000000000000000000000000000000000000000000000000000005816 206.0
SX2_k127_4588738_0 PFAM Binding-protein-dependent transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 390.0
SX2_k127_4588738_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000007612 218.0
SX2_k127_4588738_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000001287 201.0
SX2_k127_4589890_0 protein histidine kinase activity K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 394.0
SX2_k127_4604840_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001316 275.0
SX2_k127_4604840_1 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000001489 172.0
SX2_k127_4609566_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 483.0
SX2_k127_4609566_1 COG0560 Phosphoserine phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000104 226.0
SX2_k127_4610789_0 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001621 269.0
SX2_k127_4610789_1 COG2998 ABC-type tungstate transport system, permease component - - - 0.000000000000000000000000000000000000000141 156.0
SX2_k127_4610789_2 ABC-type tungstate transport system, periplasmic component - - - 0.0000000000000000000000000000000000009529 141.0
SX2_k127_4612527_0 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 442.0
SX2_k127_4623970_0 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 603.0
SX2_k127_4623970_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 317.0
SX2_k127_4630051_0 Similarity to COG0471 Di- and tricarboxylate transporters(Evalue K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 381.0
SX2_k127_4630051_1 - K14588 - - 0.00000000000000000000000000001533 123.0
SX2_k127_4630051_2 FAD binding domain - - - 0.0000000000000000000000000002156 117.0
SX2_k127_4630051_3 Uncharacterized lipoprotein K07286 - - 0.00000000003656 71.0
SX2_k127_4641096_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000004609 208.0
SX2_k127_4641096_1 PFAM Cytochrome c assembly protein - - - 0.000000000000006772 74.0
SX2_k127_4641096_2 Collagen triple helix repeat (20 copies) - - - 0.0000000001654 67.0
SX2_k127_4641096_3 Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment - GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:1901678 - 0.0000001054 54.0
SX2_k127_4674709_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 540.0
SX2_k127_4674709_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 418.0
SX2_k127_4674709_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 413.0
SX2_k127_4674709_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 383.0
SX2_k127_4678989_0 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000005222 207.0
SX2_k127_4678989_1 protein conserved in bacteria K09938 - - 0.00000000000000000000000000000944 127.0
SX2_k127_4697297_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000007723 209.0
SX2_k127_4697297_1 - - - - 0.000000000000000000000000000000000000005109 149.0
SX2_k127_4697297_2 MAPEG family - - - 0.00000000000000000000000000001948 123.0
SX2_k127_4706778_0 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 554.0
SX2_k127_4706778_1 LysR substrate binding domain - - - 0.000000000000000000000000000000006323 130.0
SX2_k127_4706778_2 Nuclear transport factor 2 (NTF2) domain - - - 0.00000000000004522 79.0
SX2_k127_4723912_0 Transcriptional regulator K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007571 245.0
SX2_k127_4723912_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000003496 148.0
SX2_k127_4723912_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03821 - - 0.0000000000000000006816 87.0
SX2_k127_4725266_0 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000007775 211.0
SX2_k127_4725266_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000001406 182.0
SX2_k127_4725266_2 - - - - 0.000000000000000000002603 102.0
SX2_k127_4725266_3 - - - - 0.00009176 48.0
SX2_k127_4739638_0 Cytochrome C1 family K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 261.0
SX2_k127_4739638_1 Stringent starvation protein A K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000007536 236.0
SX2_k127_4739638_2 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000001378 147.0
SX2_k127_4739638_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000003235 121.0
SX2_k127_4749570_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000001618 149.0
SX2_k127_4749570_1 Response regulator, receiver - - - 0.00000000000000000000000000000002472 133.0
SX2_k127_4749570_2 transduction histidine kinase - - - 0.000000000000000000000004283 117.0
SX2_k127_4750580_0 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000008267 263.0
SX2_k127_4750580_1 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000006725 127.0
SX2_k127_4756367_0 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000001099 218.0
SX2_k127_4756367_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000005564 168.0
SX2_k127_4756367_2 membrane K06077 - - 0.000000000000000000000000000000000002375 142.0
SX2_k127_4756367_3 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.00000000000000000000000000001616 118.0
SX2_k127_4763918_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 329.0
SX2_k127_4763918_1 PFAM HhH-GPD K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 253.0
SX2_k127_4763918_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000006105 145.0
SX2_k127_4763918_3 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000001012 104.0
SX2_k127_4766065_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 475.0
SX2_k127_4766065_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 441.0
SX2_k127_4766065_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 314.0
SX2_k127_4766065_3 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000000000000000000000003101 146.0
SX2_k127_4766065_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000001257 141.0
SX2_k127_4779877_0 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 325.0
SX2_k127_4779877_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000001051 265.0
SX2_k127_4779877_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000002114 254.0
SX2_k127_4779877_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000001066 143.0
SX2_k127_4779877_4 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.000008203 51.0
SX2_k127_4795741_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 333.0
SX2_k127_4795741_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000214 170.0
SX2_k127_4795741_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000002565 147.0
SX2_k127_4805195_0 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 482.0
SX2_k127_4805195_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 409.0
SX2_k127_4808128_0 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002695 280.0
SX2_k127_4808128_1 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001141 282.0
SX2_k127_4808128_2 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000841 154.0
SX2_k127_4813257_0 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 310.0
SX2_k127_4813257_1 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001885 277.0
SX2_k127_4813257_2 F plasmid transfer operon, TraF, protein - - - 0.0000000000000000000000000000000000000004559 164.0
SX2_k127_4813257_3 Ribosomal L28 family K02902 - - 0.000000000000000000000000000000002358 132.0
SX2_k127_4813257_4 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000008031 100.0
SX2_k127_4813257_5 Predicted membrane protein (DUF2238) K08984 - - 0.0001765 46.0
SX2_k127_4818829_0 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 417.0
SX2_k127_4818829_1 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 377.0
SX2_k127_4818829_2 Rubrerythrin - - - 0.0000000000000000000000000000000004134 132.0
SX2_k127_4818829_3 PFAM MazG nucleotide pyrophosphohydrolase K04765 - 3.6.1.9 0.00000000000000000000000005867 109.0
SX2_k127_4818829_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000008292 85.0
SX2_k127_4828326_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.086e-208 655.0
SX2_k127_4828326_1 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000371 265.0
SX2_k127_4833981_0 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 563.0
SX2_k127_4833981_1 amino acid - - - 0.0000000000000000000000000000000000000000000000002454 177.0
SX2_k127_4848947_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1043.0
SX2_k127_4848947_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.367e-199 628.0
SX2_k127_4848947_2 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000002473 107.0
SX2_k127_4851873_0 N-acetylmuramoyl-L-alanine amidase K01448 GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 332.0
SX2_k127_4851873_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000008682 155.0
SX2_k127_4851873_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000002164 118.0
SX2_k127_4857935_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 449.0
SX2_k127_4857935_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 415.0
SX2_k127_4857935_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001366 260.0
SX2_k127_4857935_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000002256 256.0
SX2_k127_4857935_4 Competence protein - - - 0.0000000000000000000000000000000000000000000008109 176.0
SX2_k127_4857935_5 Alpha/beta hydrolase family K02170 - 3.1.1.85 0.00000000000000000000000000000000002559 144.0
SX2_k127_486205_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 576.0
SX2_k127_486205_1 Membrane fusogenic activity K09806 - - 0.0000000000000859 74.0
SX2_k127_4880390_0 Transglycosylase SLT domain K18691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001387 247.0
SX2_k127_4880390_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000002987 229.0
SX2_k127_4880390_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000727 213.0
SX2_k127_4880390_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000001627 212.0
SX2_k127_4880390_4 Bacterial periplasmic substrate-binding proteins - - - 0.000000000000000000000000002492 121.0
SX2_k127_4891156_0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006608 246.0
SX2_k127_4891156_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000004326 237.0
SX2_k127_4891156_2 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000001098 195.0
SX2_k127_4891156_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000006196 174.0
SX2_k127_4891156_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000004143 167.0
SX2_k127_4891156_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000001451 159.0
SX2_k127_4891156_6 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000001096 138.0
SX2_k127_4891156_7 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000001363 138.0
SX2_k127_4891156_8 Ribosomal protein L30 K02907 - - 0.0000000000000000004907 90.0
SX2_k127_4930842_0 Protein of unknown function (DUF1329) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 546.0
SX2_k127_4930842_1 Protein of unknown function (DUF1302) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001213 248.0
SX2_k127_4937916_0 Glutamate-cysteine ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009871 397.0
SX2_k127_4937916_1 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000003539 232.0
SX2_k127_4937916_2 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000008402 178.0
SX2_k127_4937916_3 glutamate--cysteine ligase K01919 - 6.3.2.2 0.000000000000000000000000000000000000000001967 158.0
SX2_k127_4937916_4 Belongs to the 'phage' integrase family - - - 0.00000004666 56.0
SX2_k127_4941389_0 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 540.0
SX2_k127_4941389_1 Pilus assembly protein K02662 - - 0.00000000000000000000000000558 112.0
SX2_k127_4942430_0 response regulator receiver K13041 - - 0.00000000000000000000000000000000000000000000000000000000000005706 219.0
SX2_k127_4942430_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000002426 170.0
SX2_k127_4942430_2 Cold shock K03704 - - 0.00000000000000000000001836 105.0
SX2_k127_4942430_3 - - - - 0.00000000000000000006551 97.0
SX2_k127_4942430_4 PilZ domain - - - 0.0008164 48.0
SX2_k127_4942608_0 Virulence factor BrkB K07058 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000001484 222.0
SX2_k127_4942608_1 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000001261 151.0
SX2_k127_4942608_2 acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000003795 101.0
SX2_k127_4945599_0 small GTP-binding protein K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 565.0
SX2_k127_4955130_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 9.815e-224 716.0
SX2_k127_4955130_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.058e-206 645.0
SX2_k127_4955130_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006991 276.0
SX2_k127_4955130_3 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000566 114.0
SX2_k127_4955130_4 Sel1-like repeats. - - - 0.0000000000007389 78.0
SX2_k127_4960264_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006599 586.0
SX2_k127_4960264_1 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000001785 227.0
SX2_k127_4960264_2 COG3175 Cytochrome oxidase assembly factor K02258 - - 0.00000000000000000000000000000000000000000000000135 181.0
SX2_k127_4980569_0 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 283.0
SX2_k127_4980569_1 Belongs to the Fur family K09823 - - 0.000000000000000000000000000000000000000000000000000000000000001138 222.0
SX2_k127_4980569_2 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000007993 195.0
SX2_k127_4980569_3 Phage integrase family - - - 0.0000000000000000000000000000000008366 131.0
SX2_k127_4980569_4 PFAM response regulator receiver - - - 0.000000000000000000000000003262 119.0
SX2_k127_4980569_5 sulfur carrier activity K00549,K04085,K04487 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.00000000000000001934 87.0
SX2_k127_4980569_6 PFAM periplasmic solute binding protein K09815 - - 0.000001894 53.0
SX2_k127_4980569_7 helix_turn_helix, Lux Regulon - - - 0.0002569 51.0
SX2_k127_5010487_0 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.102 1.29e-217 691.0
SX2_k127_5033953_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 531.0
SX2_k127_5033953_1 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517,K12974 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000001318 207.0
SX2_k127_504462_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 4.954e-229 718.0
SX2_k127_504462_1 Modulates RecA activity K03565 - - 0.00000000000000000000021 99.0
SX2_k127_5053029_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 454.0
SX2_k127_5053029_1 PFAM MucB RseB K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000001067 238.0
SX2_k127_5053639_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 446.0
SX2_k127_5053639_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 417.0
SX2_k127_5053639_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000009872 155.0
SX2_k127_5053639_3 NlpB/DapX lipoprotein K07287 - - 0.000000000000000000000000000000000000143 155.0
SX2_k127_5053639_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000001026 57.0
SX2_k127_5053639_5 Galactose-1-phosphate uridyl transferase, N-terminal domain - - - 0.0000000533 54.0
SX2_k127_5062997_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008255 273.0
SX2_k127_5062997_1 - - - - 0.000000000000000006466 91.0
SX2_k127_5075167_0 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000008026 235.0
SX2_k127_5075167_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000006393 168.0
SX2_k127_5075167_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K01498,K11752 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.193,3.5.4.26 0.00000000000000000195 86.0
SX2_k127_5087735_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.021e-228 730.0
SX2_k127_5087735_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 611.0
SX2_k127_5087735_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 299.0
SX2_k127_5087735_3 penicillin-binding protein 1A K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.0000000004807 61.0
SX2_k127_5097390_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000732 278.0
SX2_k127_5097390_1 GGDEF domain - - - 0.000000000000000000000000004216 119.0
SX2_k127_5098993_0 PFAM ABC transporter K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 389.0
SX2_k127_5098993_1 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000179 268.0
SX2_k127_5098993_2 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000001765 168.0
SX2_k127_5108190_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 589.0
SX2_k127_5108190_1 transport system, permease component - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000001214 233.0
SX2_k127_5110709_0 serine threonine protein kinase K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 307.0
SX2_k127_5110709_1 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.00000000000274 68.0
SX2_k127_5128084_0 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000003165 222.0
SX2_k127_5128084_1 Type II secretory pathway, pseudopilin PulG K10924 - - 0.0000000000000000000000003726 109.0
SX2_k127_5128084_2 general secretion pathway protein - - - 0.00000000000004481 75.0
SX2_k127_5130152_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 538.0
SX2_k127_5130152_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 349.0
SX2_k127_5130152_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 289.0
SX2_k127_5130152_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000002655 244.0
SX2_k127_5130152_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000003904 233.0
SX2_k127_5130152_5 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000000000000000000000005516 198.0
SX2_k127_5145240_0 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 3.004e-200 636.0
SX2_k127_5145240_1 Type II secretion system K02653 - - 0.00005155 48.0
SX2_k127_516527_0 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 522.0
SX2_k127_516527_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 413.0
SX2_k127_516527_2 Pyrroloquinoline quinone biosynthesis protein E K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 391.0
SX2_k127_516527_3 coenzyme PQQ synthesis K06138 - - 0.00000000000000000000000003145 113.0
SX2_k127_5174747_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 1.089e-316 976.0
SX2_k127_5174747_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000001122 208.0
SX2_k127_5174747_2 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.0000000000000000000000000000000000000001975 153.0
SX2_k127_5174747_3 succinate dehydrogenase K00242 - - 0.0000000000000000000000001152 111.0
SX2_k127_5174747_4 Protein of unknown function (DUF1674) - - - 0.0000000003246 62.0
SX2_k127_5183608_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.356e-219 687.0
SX2_k127_5183608_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 387.0
SX2_k127_5183608_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 296.0
SX2_k127_5183608_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000005261 156.0
SX2_k127_5183608_4 Lipopolysaccharide assembly protein A domain K08992 - - 0.000000004153 61.0
SX2_k127_5185701_0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 295.0
SX2_k127_5185701_1 Peptidase C26 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005752 250.0
SX2_k127_5185701_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.0000000000000000000000000000000000000000000000000000000000002996 218.0
SX2_k127_5185701_3 TIGRFAM Type VI secretion system effector, Hcp1 K11903 - - 0.0000000000000000006225 93.0
SX2_k127_5185701_4 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.00000006915 55.0
SX2_k127_5187868_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 349.0
SX2_k127_5187868_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000001189 194.0
SX2_k127_519351_0 von willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 383.0
SX2_k127_519351_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000003376 170.0
SX2_k127_5202292_0 Diguanylate cyclase - - - 0.000000000000000000000000000002511 134.0
SX2_k127_5202292_1 Type II secretion system protein B K02451 - - 0.00000001085 64.0
SX2_k127_5204442_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 387.0
SX2_k127_5204442_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000006062 181.0
SX2_k127_5215566_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 531.0
SX2_k127_5215566_1 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 332.0
SX2_k127_5215566_2 COG0811 Biopolymer transport proteins K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0017038,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0033036,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001998 271.0
SX2_k127_5215566_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000004816 248.0
SX2_k127_5215566_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000002985 186.0
SX2_k127_5215566_5 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000000000000008821 157.0
SX2_k127_5215566_6 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000001629 141.0
SX2_k127_5228626_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 385.0
SX2_k127_5228626_1 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 340.0
SX2_k127_5228626_2 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002595 278.0
SX2_k127_5231689_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 463.0
SX2_k127_5231689_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 431.0
SX2_k127_5231689_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001294 276.0
SX2_k127_5231689_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000007316 177.0
SX2_k127_5231689_4 - K06950 - - 0.000000005514 59.0
SX2_k127_5245102_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 331.0
SX2_k127_5245102_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000005406 82.0
SX2_k127_5247722_0 amino acid - - - 2.655e-242 756.0
SX2_k127_5247722_1 Ethanolamine ammonia lyase large subunit K03735 - 4.3.1.7 2.44e-237 739.0
SX2_k127_5247722_2 Belongs to the EutC family K03736 - 4.3.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 320.0
SX2_k127_5247722_3 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.6.1.41 0.000000000004151 68.0
SX2_k127_5269001_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 584.0
SX2_k127_5269001_1 - - - - 0.00000000004978 68.0
SX2_k127_5275986_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 518.0
SX2_k127_5275986_1 NnrU protein K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 334.0
SX2_k127_5275986_2 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006 244.0
SX2_k127_5275986_3 Bacterial PH domain - - - 0.00000000000000000000000000000000000000000000004137 173.0
SX2_k127_5275986_4 general secretion pathway protein - - - 0.00000000000000000000000000000000000000003856 162.0
SX2_k127_5291861_0 COG1077 Actin-like ATPase involved in cell morphogenesis K03569 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 572.0
SX2_k127_5291861_1 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001866 277.0
SX2_k127_5291861_2 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000000000000000000000000000000000888 169.0
SX2_k127_5294409_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 524.0
SX2_k127_5294409_1 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000006777 218.0
SX2_k127_5294409_2 PFAM helix-turn-helix domain protein - - - 0.00000000000000000000000000003396 119.0
SX2_k127_5294409_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000005747 64.0
SX2_k127_5294409_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000004869 49.0
SX2_k127_5294409_6 Phage derived protein Gp49-like (DUF891) - - - 0.0001792 48.0
SX2_k127_5294409_7 Helix-turn-helix domain - - - 0.0003014 47.0
SX2_k127_5303924_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 320.0
SX2_k127_5303924_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 314.0
SX2_k127_5303924_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000006155 196.0
SX2_k127_5303924_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000003493 122.0
SX2_k127_5320098_0 belongs to the Fur family K09826 - - 0.0000000000000000000000000000000000000001086 157.0
SX2_k127_5320098_1 Oxidative deamination of D-amino acids K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 0.0000000000000000000000000000001313 126.0
SX2_k127_5327059_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 358.0
SX2_k127_5327059_1 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000000000000000000001799 151.0
SX2_k127_5327059_2 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000004351 60.0
SX2_k127_5343412_0 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 483.0
SX2_k127_5343412_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 422.0
SX2_k127_5343412_2 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000002019 136.0
SX2_k127_5350078_0 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 411.0
SX2_k127_5350078_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000002648 241.0
SX2_k127_5350078_2 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.0007563 44.0
SX2_k127_537229_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000004856 196.0
SX2_k127_537229_1 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000002689 65.0
SX2_k127_5383604_0 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000003426 236.0
SX2_k127_5383604_1 PFAM multicopper oxidase type - - - 0.0000000000000000000000000000002482 129.0
SX2_k127_5392787_0 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1384.0
SX2_k127_5397560_0 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 1.514e-198 627.0
SX2_k127_5397560_1 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 317.0
SX2_k127_5397560_2 Belongs to the UPF0149 family K09895 - - 0.00000000000000000000003174 107.0
SX2_k127_5397560_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000015 98.0
SX2_k127_5397560_4 EVE domain - - - 0.000000000000001308 76.0
SX2_k127_5397560_5 - - - - 0.000000000003529 68.0
SX2_k127_5410356_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 432.0
SX2_k127_5410356_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000106 256.0
SX2_k127_5416002_0 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 - 3.5.1.28 0.0000000000000000000000000000000004442 134.0
SX2_k127_5416002_1 COG3023 Negative regulator of beta-lactamase expression K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.000000000000000000000000000000002447 130.0
SX2_k127_5416002_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.1.10 0.0000000000000000000000000000007707 132.0
SX2_k127_5416002_3 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 0.0004185 44.0
SX2_k127_5433960_0 Phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 325.0
SX2_k127_5433960_1 - - - - 0.000000000000000000000000000000000000000007365 157.0
SX2_k127_5433960_2 ABC-type tungstate transport system, periplasmic component K05773 - - 0.0000000000000000001475 90.0
SX2_k127_5433960_3 - - - - 0.000000001652 62.0
SX2_k127_5439104_0 Alpha-2-Macroglobulin K06894 - - 9.315e-199 631.0
SX2_k127_5461891_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1207.0
SX2_k127_5461891_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 443.0
SX2_k127_5496717_0 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001093 258.0
SX2_k127_5496717_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000006803 241.0
SX2_k127_5519668_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 426.0
SX2_k127_5519668_1 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000000000001886 123.0
SX2_k127_5519668_2 PFAM EAL domain K21025 - - 0.00006391 50.0
SX2_k127_5521184_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000001378 173.0
SX2_k127_5521184_1 Sel1-like repeats. K07126 - - 0.0000000000000000000001354 103.0
SX2_k127_5521184_2 COG4235 Cytochrome c biogenesis factor K02200 - - 0.0000000000000009228 79.0
SX2_k127_5524337_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 442.0
SX2_k127_5524337_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 437.0
SX2_k127_5524337_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 369.0
SX2_k127_552660_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 3.5e-311 975.0
SX2_k127_552660_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000001606 125.0
SX2_k127_5539807_0 (ABC) transporter K11004,K13409 - - 2.981e-300 936.0
SX2_k127_5539807_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.085e-200 629.0
SX2_k127_5539807_2 S23 ribosomal protein - - - 0.000000000000000000000000000000000000000001324 160.0
SX2_k127_5547580_0 PFAM filamentation induced by cAMP protein Fic - - - 2.534e-210 664.0
SX2_k127_5547580_1 methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0000000000000000000007966 95.0
SX2_k127_5547580_2 methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.000000000001482 68.0
SX2_k127_5550538_0 flavoproteins K07007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 499.0
SX2_k127_5550538_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 315.0
SX2_k127_5550538_2 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002624 273.0
SX2_k127_5550538_3 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001422 269.0
SX2_k127_5550538_4 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004676 258.0
SX2_k127_5550538_5 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000003397 246.0
SX2_k127_5550538_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000001795 109.0
SX2_k127_5550538_7 dUTPase - - - 0.00000000000000000001293 97.0
SX2_k127_5554335_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 588.0
SX2_k127_5554335_1 GDP-mannose 4,6 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 298.0
SX2_k127_5554335_2 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.00000003978 54.0
SX2_k127_55623_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 373.0
SX2_k127_55623_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000003786 250.0
SX2_k127_55623_2 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 0.00000000000000000000000000000000007056 139.0
SX2_k127_5640441_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 353.0
SX2_k127_5641554_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 572.0
SX2_k127_5641554_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 396.0
SX2_k127_5641554_2 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000002337 181.0
SX2_k127_5641554_3 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 0.0000000000000000000000000000000000000000001329 162.0
SX2_k127_565408_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 9.981e-236 741.0
SX2_k127_565408_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000046 251.0
SX2_k127_5656847_0 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000003351 183.0
SX2_k127_5656847_1 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000005017 169.0
SX2_k127_5656847_2 formate dehydrogenase - - - 0.00000000000000000000000000000000009764 145.0
SX2_k127_5660805_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008835 466.0
SX2_k127_5660805_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 453.0
SX2_k127_5660805_2 Cache_2 K08738 - - 0.000000000000000000000000000000000000000000001351 166.0
SX2_k127_5686110_0 FAD dependent oxidoreductase K00303,K10816 - 1.4.99.5,1.5.3.1 2.505e-226 706.0
SX2_k127_5686110_1 PFAM Sarcosine oxidase, delta subunit, heterotetrameric K00304 - 1.5.3.1 0.0000000001217 63.0
SX2_k127_5697204_0 Conserved region in glutamate synthase K22083 - 2.1.1.21 1.276e-264 816.0
SX2_k127_5697204_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001011 212.0
SX2_k127_5697204_2 Belongs to the AB hydrolase superfamily. MetX family K00641 - 2.3.1.31 0.00000000000000000000000000000000000000004639 154.0
SX2_k127_569768_0 Peptidase C13 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 313.0
SX2_k127_569768_1 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000002537 207.0
SX2_k127_569768_2 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000454 204.0
SX2_k127_569768_3 - - - - 0.0000000005811 60.0
SX2_k127_5702042_0 FtsX-like permease family K02004 - - 1.038e-233 749.0
SX2_k127_5702042_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.455e-231 721.0
SX2_k127_5702042_2 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 586.0
SX2_k127_5702042_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 299.0
SX2_k127_5702042_4 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 295.0
SX2_k127_5702042_5 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000595 251.0
SX2_k127_5702042_6 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000381 209.0
SX2_k127_5702042_7 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000005846 165.0
SX2_k127_5702042_8 PIN domain - - - 0.0000000000000000000000123 106.0
SX2_k127_5702042_9 toxin-antitoxin pair type II binding - - - 0.0001185 49.0
SX2_k127_5703600_0 PFAM transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 325.0
SX2_k127_5703600_1 nitrous oxide reductase K00376 - 1.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001388 258.0
SX2_k127_5714072_0 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 319.0
SX2_k127_5714072_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003815 255.0
SX2_k127_5714072_2 Protein of unknown function (DUF3450) - - - 0.0000000000000000000000000000000008978 136.0
SX2_k127_5734874_0 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 384.0
SX2_k127_5734874_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 302.0
SX2_k127_5734874_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000001441 180.0
SX2_k127_5740793_0 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000174 181.0
SX2_k127_5740793_1 membrane - - - 0.00000000000000000000000000000000000000001719 165.0
SX2_k127_5740793_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001717 127.0
SX2_k127_5795198_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 386.0
SX2_k127_5795198_1 HlyD family K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 308.0
SX2_k127_5795198_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000003132 107.0
SX2_k127_5814300_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 550.0
SX2_k127_5814300_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002024 260.0
SX2_k127_5830122_0 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 361.0
SX2_k127_5830122_1 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000000005044 191.0
SX2_k127_5856145_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 364.0
SX2_k127_5856145_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.0000000000000000000000000000000000000000002071 162.0
SX2_k127_5856145_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000001369 142.0
SX2_k127_5863803_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 8.348e-279 881.0
SX2_k127_5863803_1 Participates in both transcription termination and antitermination K02600 - - 2.729e-220 693.0
SX2_k127_5863803_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 363.0
SX2_k127_5863803_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000003621 156.0
SX2_k127_5863803_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000002749 127.0
SX2_k127_5863803_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000001554 95.0
SX2_k127_5863803_6 - - - - 0.000000002705 58.0
SX2_k127_5863803_7 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.000001301 50.0
SX2_k127_5883601_0 amino acid - - - 2.136e-247 774.0
SX2_k127_5883601_1 acyl-coa dehydrogenase - - - 0.000000000000000000004457 93.0
SX2_k127_5883601_2 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000002779 93.0
SX2_k127_5895204_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 437.0
SX2_k127_5895204_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 419.0
SX2_k127_5895204_2 COG1131 ABC-type multidrug transport system, ATPase component K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 407.0
SX2_k127_5895204_3 Transport permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 360.0
SX2_k127_5895204_4 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 328.0
SX2_k127_5895204_5 TIGRFAM Lytic murein transglycosylase B K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 314.0
SX2_k127_5895204_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 289.0
SX2_k127_5895204_7 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007392 258.0
SX2_k127_5895204_8 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000003779 195.0
SX2_k127_5895204_9 Cyclic nucleotide-monophosphate binding domain K03301 - - 0.00000003828 60.0
SX2_k127_5896252_0 Major Facilitator Superfamily - - - 1.459e-260 814.0
SX2_k127_5896252_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 354.0
SX2_k127_5896252_2 PFAM Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000006232 158.0
SX2_k127_5910244_0 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 389.0
SX2_k127_5919473_0 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 418.0
SX2_k127_5919473_1 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 327.0
SX2_k127_5919473_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 316.0
SX2_k127_5919473_3 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 310.0
SX2_k127_5919473_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 292.0
SX2_k127_5919473_5 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000001553 235.0
SX2_k127_5919473_6 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000003901 140.0
SX2_k127_5919473_7 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000001314 143.0
SX2_k127_5919473_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000002719 93.0
SX2_k127_5924594_0 PFAM Isocitrate dehydrogenase NADP-dependent monomeric type K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 570.0
SX2_k127_5929367_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002231 310.0
SX2_k127_5929367_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000001643 181.0
SX2_k127_5929367_2 diguanylate cyclase - - - 0.000000000000000000000000000000000003203 146.0
SX2_k127_5929367_3 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000005507 128.0
SX2_k127_5929367_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000001027 55.0
SX2_k127_5942992_0 FAD linked oxidase K00104 - 1.1.3.15 2.223e-210 662.0
SX2_k127_5942992_1 COG1530 Ribonucleases G and E K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 497.0
SX2_k127_5956330_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 393.0
SX2_k127_5956330_1 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000839 68.0
SX2_k127_5986791_0 PFAM binding-protein-dependent transport systems inner membrane component K02037 - - 5.032e-295 921.0
SX2_k127_5986791_1 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 2.92e-219 696.0
SX2_k127_5986791_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 379.0
SX2_k127_600869_0 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 509.0
SX2_k127_600869_1 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 333.0
SX2_k127_600869_2 membrane-anchored protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002907 284.0
SX2_k127_600869_3 - - - - 0.0000000000000000000000000000000000000000000000003286 184.0
SX2_k127_600869_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000008174 175.0
SX2_k127_600869_5 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000402 98.0
SX2_k127_600869_6 Sulfotransferase domain - - - 0.0000001603 58.0
SX2_k127_6021008_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 7.571e-211 658.0
SX2_k127_6021008_1 ACT domain - - - 0.000000000000000000000000000000000000000000000000000009131 192.0
SX2_k127_6021008_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000002853 188.0
SX2_k127_6028159_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 512.0
SX2_k127_6028159_1 oxidase, subunit K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 309.0
SX2_k127_6028159_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000005144 104.0
SX2_k127_6047618_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 554.0
SX2_k127_6047618_1 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009542 266.0
SX2_k127_6047618_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000327 203.0
SX2_k127_6047618_3 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000001469 117.0
SX2_k127_608910_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004738 253.0
SX2_k127_608910_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000001932 212.0
SX2_k127_608910_2 TIGRFAM CRISPR-associated protein - - - 0.0000000000000000000000000000000000000000000003002 171.0
SX2_k127_629853_0 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000001758 231.0
SX2_k127_629853_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000319 218.0
SX2_k127_629853_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000006099 191.0
SX2_k127_629853_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000008771 152.0
SX2_k127_629853_4 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000002806 153.0
SX2_k127_629853_5 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000008448 123.0
SX2_k127_629853_6 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000004667 81.0
SX2_k127_637778_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.593e-272 846.0
SX2_k127_637778_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 580.0
SX2_k127_637778_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 528.0
SX2_k127_637778_3 protein methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 319.0
SX2_k127_637778_4 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000002838 175.0
SX2_k127_637778_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000004414 156.0
SX2_k127_637778_6 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000001139 150.0
SX2_k127_638816_0 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 388.0
SX2_k127_638816_1 biosynthesis protein HemY K02498 - - 0.00000000000000000000000000000000000000000000000000000000003597 222.0
SX2_k127_638816_2 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000007007 193.0
SX2_k127_678756_0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000756 177.0
SX2_k127_678756_1 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000003987 159.0
SX2_k127_678756_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000001803 133.0
SX2_k127_682883_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000003247 204.0
SX2_k127_682883_1 Cupin domain - - - 0.0000000000000001699 81.0
SX2_k127_682883_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0000000000000004982 82.0
SX2_k127_699687_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 377.0
SX2_k127_699687_1 Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair K03573 - - 0.00000000000000000000000000000000000000000000000000000000000000000005249 238.0
SX2_k127_699687_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000001744 167.0
SX2_k127_705894_0 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006757 260.0
SX2_k127_705894_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008353 251.0
SX2_k127_705894_2 - - - - 0.000000004544 66.0
SX2_k127_727096_0 Radical SAM - - - 8.705e-223 700.0
SX2_k127_727096_1 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 301.0
SX2_k127_727096_2 YdjC-like protein - - - 0.000000000000000000000000000000000000000000000002533 176.0
SX2_k127_727096_3 NnrU protein - - - 0.0000000000000000000000000001775 118.0
SX2_k127_754893_0 Helicase K03722 - 3.6.4.12 4.107e-206 660.0
SX2_k127_754893_1 Elongation factor P--(R)-beta-lysine ligase K04568 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000001823 162.0
SX2_k127_754893_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000003006 119.0
SX2_k127_761588_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 7.322e-307 951.0
SX2_k127_761588_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 332.0
SX2_k127_761588_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009351 239.0
SX2_k127_761588_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000002716 172.0
SX2_k127_761588_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000883 85.0
SX2_k127_769153_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 388.0
SX2_k127_769153_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000156 235.0
SX2_k127_769153_2 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000001607 242.0
SX2_k127_775314_0 Sigma-70 factor, region 1.2 K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 420.0
SX2_k127_775314_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 293.0
SX2_k127_775314_2 peptidase K06194 - - 0.00000000000000000000000000000000000000000000000000000000483 207.0
SX2_k127_775314_3 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000003355 126.0
SX2_k127_78121_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 338.0
SX2_k127_78121_1 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000007804 177.0
SX2_k127_78121_2 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000001502 119.0
SX2_k127_785323_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 571.0
SX2_k127_785323_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 476.0
SX2_k127_785323_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000007357 205.0
SX2_k127_785323_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000007442 176.0
SX2_k127_806521_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 390.0
SX2_k127_806521_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 363.0
SX2_k127_806521_2 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000004033 179.0
SX2_k127_806521_3 HemX, putative uroporphyrinogen-III C-methyltransferase K02496 - 2.1.1.107 0.00000000000000000000000001873 120.0
SX2_k127_806521_4 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000001183 72.0
SX2_k127_809114_0 similarity to OMNI NTL01RS2573 K07485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 291.0
SX2_k127_809114_1 Alkyl hydroperoxide reductase - - - 0.0000000000000000000000003006 105.0
SX2_k127_826009_0 peptidase K01414 - 3.4.24.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 339.0
SX2_k127_826009_1 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 331.0
SX2_k127_826009_2 PFAM cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000244 229.0
SX2_k127_826009_3 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000004994 199.0
SX2_k127_826009_4 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000029 117.0
SX2_k127_826009_5 PFAM Staphylococcal nuclease - - - 0.000000000000000000004189 102.0
SX2_k127_826009_6 Thiol disulfide interchange protein K03673 - - 0.0000000000000004844 79.0
SX2_k127_826009_7 Bacterial SH3 domain homologues K07184 - - 0.0000007066 61.0
SX2_k127_83872_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 408.0
SX2_k127_83872_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 406.0
SX2_k127_83872_2 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000000003688 151.0
SX2_k127_839172_0 PFAM ErfK YbiS YcfS YnhG family protein K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 311.0
SX2_k127_839172_1 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000008367 147.0
SX2_k127_839172_2 (Lipo)protein - - - 0.00000005215 58.0
SX2_k127_839172_3 Putative peptidoglycan binding domain - - - 0.0000004909 56.0
SX2_k127_844925_0 Cytochrome c - - - 0.0 1139.0
SX2_k127_844925_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000001289 73.0
SX2_k127_864742_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 518.0
SX2_k127_864742_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 478.0
SX2_k127_864742_2 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 454.0
SX2_k127_864742_3 Hemolysin activation secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 390.0
SX2_k127_866796_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 342.0
SX2_k127_866796_1 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 325.0
SX2_k127_866796_2 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000004523 162.0
SX2_k127_889301_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 2.217e-211 691.0
SX2_k127_889301_1 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000006504 235.0
SX2_k127_889301_2 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000003001 200.0
SX2_k127_889301_3 Histidine kinase - - - 0.0000000000000000000000004243 106.0
SX2_k127_889301_4 response regulator K02282,K07705 - - 0.00000000000000000000002578 104.0
SX2_k127_889301_5 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.00000000000000000000006442 103.0
SX2_k127_89157_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 554.0
SX2_k127_89157_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 388.0
SX2_k127_89157_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 368.0
SX2_k127_89157_3 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000003762 180.0
SX2_k127_89157_4 PFAM toluene tolerance K07323 - - 0.000000000000000000000000000000000000000000000383 174.0
SX2_k127_89157_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000001712 140.0
SX2_k127_89157_6 Belongs to the BolA IbaG family - - - 0.00000000000000000000008492 100.0
SX2_k127_89157_7 NTP binding protein (Contains STAS domain) K07122 - - 0.000000000001037 72.0
SX2_k127_915254_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1049.0
SX2_k127_915254_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000005053 224.0
SX2_k127_915254_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000000000000002191 201.0
SX2_k127_915254_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000002975 135.0
SX2_k127_915254_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000001544 53.0
SX2_k127_915254_5 - - - - 0.0000002859 51.0
SX2_k127_931219_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000002058 256.0
SX2_k127_931219_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000009075 220.0
SX2_k127_931219_2 MAPEG family - - - 0.00000000000000000000000000000001927 133.0
SX2_k127_931219_3 methyltransferase FkbM - - - 0.00000000000000000001795 102.0
SX2_k127_940076_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 3.437e-211 662.0
SX2_k127_940076_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000004199 79.0
SX2_k127_945734_0 Protein of unknown function, DUF255 K06888 - - 9.022e-254 801.0
SX2_k127_945734_1 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.0000000000000000000000000000000001646 135.0
SX2_k127_945734_2 Cupredoxin-like domain - - - 0.00000000000000000000000000000007629 127.0
SX2_k127_956360_0 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 472.0
SX2_k127_956360_1 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002275 275.0
SX2_k127_956360_2 PFAM binding-protein-dependent transport systems inner membrane component K02037 - - 0.0000000000000000418 85.0
SX2_k127_99482_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 343.0
SX2_k127_99482_1 PFAM ApaG domain protein K06195 - - 0.00000000000000000000000000000000000000000000000003805 181.0
SX2_k127_99482_2 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000007053 134.0
SX2_k127_99482_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000001142 104.0