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Overview

ID MAG03644
Name SX2_bin.28
Sample SMP0092
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Coriobacteriia
Order Anaerosomatales
Family PALSA-660
Genus
Species
Assembly information
Completeness (%) 56.09
Contamination (%) 0.79
GC content (%) 69.0
N50 (bp) 5,729
Genome size (bp) 925,815

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes907

Gene name Description KEGG GOs EC E-value Score Sequence
SX2_k127_1080923_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 5.724e-232 724.0
SX2_k127_1080923_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 9.078e-228 722.0
SX2_k127_1080923_2 Glucosamine-6-phosphate deaminase K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 436.0
SX2_k127_1080923_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000001885 252.0
SX2_k127_1080923_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000001372 225.0
SX2_k127_1080923_5 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000000000000000000000000003593 214.0
SX2_k127_1080923_6 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001214 162.0
SX2_k127_1088691_0 Metal ion transporter, metal ion (Mn2 Fe2 ) transporter (Nramp) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 443.0
SX2_k127_1088691_1 Magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000008876 213.0
SX2_k127_1115655_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.314e-232 740.0
SX2_k127_1115655_1 COGs COG1125 ABC-type proline glycine betaine transport systems ATPase components K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 346.0
SX2_k127_1115655_2 dihydropteroate synthase K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 310.0
SX2_k127_1115655_3 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000235 291.0
SX2_k127_1115655_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000002644 239.0
SX2_k127_1115655_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000001723 262.0
SX2_k127_1115655_6 glycine betaine transport K05846 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - 0.0000000000000000000000000000000000000000000000000000000000000000002993 250.0
SX2_k127_1115655_7 permease K05846 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - 0.00000000000000000000000000000000000000000000000000004473 196.0
SX2_k127_1115655_8 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000004375 174.0
SX2_k127_1115655_9 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000002616 130.0
SX2_k127_1144025_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000007654 254.0
SX2_k127_1170755_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 462.0
SX2_k127_1170755_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 354.0
SX2_k127_1170755_2 Elongation factor SelB winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000001453 241.0
SX2_k127_1170755_3 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000118 223.0
SX2_k127_1170755_4 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000005161 114.0
SX2_k127_1170755_5 DsrE/DsrF-like family K04085 - - 0.00000000000000000000002009 104.0
SX2_k127_1172665_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.462e-291 908.0
SX2_k127_1172665_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.076e-206 659.0
SX2_k127_1172665_2 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000006901 128.0
SX2_k127_1172665_3 - - - - 0.000000000004644 73.0
SX2_k127_1172665_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0007567 47.0
SX2_k127_1184832_0 DnaQ family exonuclease DinG family helicase K03722 - 3.6.4.12 3.821e-220 717.0
SX2_k127_1184832_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 604.0
SX2_k127_1184832_2 L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000007817 220.0
SX2_k127_1289261_0 biogenesis protein CcmF K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 485.0
SX2_k127_1289261_1 PFAM ABC transporter K01990,K02193,K09697 - 3.6.3.41,3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 313.0
SX2_k127_1289261_2 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 294.0
SX2_k127_1289261_3 PFAM helix-turn-helix domain protein - - - 0.00000000000000000000000000000000000001344 154.0
SX2_k127_1289261_4 heme exporter protein CcmB K02194 - - 0.0000000000000000000000000002829 117.0
SX2_k127_1289261_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000227 104.0
SX2_k127_1289261_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000003059 93.0
SX2_k127_1332017_0 PFAM FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 528.0
SX2_k127_1332017_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 443.0
SX2_k127_1332017_2 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000106 173.0
SX2_k127_1332017_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000008378 151.0
SX2_k127_1332017_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000003396 132.0
SX2_k127_1332017_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000002262 125.0
SX2_k127_1332017_6 peptidase - - - 0.00000000005817 74.0
SX2_k127_1332017_7 - - - - 0.00001235 57.0
SX2_k127_1384780_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 363.0
SX2_k127_1384780_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000007799 214.0
SX2_k127_1384780_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000001879 208.0
SX2_k127_1384780_3 PFAM peptidase K21471 - - 0.000000000000000000000000000000000000000000000000001161 197.0
SX2_k127_1384780_4 domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000001837 157.0
SX2_k127_1384780_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000001093 141.0
SX2_k127_1384780_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000001099 141.0
SX2_k127_1390375_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 601.0
SX2_k127_1390375_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 561.0
SX2_k127_1390375_2 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 353.0
SX2_k127_1390375_3 4Fe-4S binding domain K02572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 310.0
SX2_k127_1390375_4 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002717 261.0
SX2_k127_1390375_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000006131 139.0
SX2_k127_1390375_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000002973 100.0
SX2_k127_1390375_7 Belongs to the DEAD box helicase family K03732,K11927 - 3.6.4.13 0.00000000000002552 81.0
SX2_k127_1390375_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00004851 54.0
SX2_k127_1390375_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0005324 49.0
SX2_k127_1415978_0 Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP K05716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 374.0
SX2_k127_1415978_1 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 305.0
SX2_k127_1415978_2 2-phosphoglycerate kinase K05715 - - 0.000000000000000000000000000000000000000000000000007775 201.0
SX2_k127_1415978_3 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000002959 100.0
SX2_k127_1429564_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 580.0
SX2_k127_1429564_1 FeS-containing Cyanobacterial-specific oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 352.0
SX2_k127_1429564_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 302.0
SX2_k127_1429564_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000003101 140.0
SX2_k127_144679_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.478e-226 730.0
SX2_k127_144679_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 298.0
SX2_k127_144679_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000002813 139.0
SX2_k127_144679_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000002139 128.0
SX2_k127_144679_4 - - - - 0.00000000000000000000000005013 116.0
SX2_k127_144679_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000008724 104.0
SX2_k127_1449213_0 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 343.0
SX2_k127_1449213_1 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003739 263.0
SX2_k127_1449213_2 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.0000000000001543 76.0
SX2_k127_1450347_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 388.0
SX2_k127_1450347_1 prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 311.0
SX2_k127_1450347_2 May catalyze the transamination reaction in phenylalanine biosynthesis K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000008907 261.0
SX2_k127_1475449_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 551.0
SX2_k127_1475449_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 405.0
SX2_k127_1475449_2 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 362.0
SX2_k127_1475449_3 EamA-like transporter family - - - 0.0000000000000000000000004508 116.0
SX2_k127_1475449_4 VanZ like family - - - 0.00000000000000006158 86.0
SX2_k127_1517635_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.898e-235 741.0
SX2_k127_1517635_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000001346 240.0
SX2_k127_1517635_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000009143 123.0
SX2_k127_1595121_0 ABC transporter K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000003095 242.0
SX2_k127_1595121_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002039 244.0
SX2_k127_1595121_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000003242 144.0
SX2_k127_1595121_3 Domain of unknown function (DUF4287) - - - 0.0000000000000711 75.0
SX2_k127_1595121_4 FtsX-like permease family K09808 - - 0.0000000000752 68.0
SX2_k127_161412_0 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001186 276.0
SX2_k127_161412_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000006314 225.0
SX2_k127_161412_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000005769 201.0
SX2_k127_161412_3 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000002132 137.0
SX2_k127_1618689_0 Putative glucoamylase K13688 - - 0.0 1242.0
SX2_k127_1618689_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1123.0
SX2_k127_1618689_10 IA, variant 3 K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000000267 173.0
SX2_k127_1618689_11 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000002818 153.0
SX2_k127_1618689_12 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000005011 151.0
SX2_k127_1618689_13 MFS/sugar transport protein - - - 0.0000000000000000000000000000000004006 147.0
SX2_k127_1618689_14 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000009502 116.0
SX2_k127_1618689_16 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000006372 78.0
SX2_k127_1618689_17 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000001249 80.0
SX2_k127_1618689_18 TIGRFAM RND family efflux transporter, MFP subunit K02005 - - 0.000000000003843 79.0
SX2_k127_1618689_19 B-1 B cell differentiation K07126 - - 0.000000000008218 78.0
SX2_k127_1618689_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.648e-257 807.0
SX2_k127_1618689_20 - - - - 0.00004872 46.0
SX2_k127_1618689_21 Protein of unknown function (DUF721) - - - 0.0008502 49.0
SX2_k127_1618689_3 Bacterial dnaA protein helix-turn-helix domain K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 471.0
SX2_k127_1618689_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 315.0
SX2_k127_1618689_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 324.0
SX2_k127_1618689_6 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 309.0
SX2_k127_1618689_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000699 279.0
SX2_k127_1618689_8 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001098 232.0
SX2_k127_1618689_9 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000002762 213.0
SX2_k127_1622477_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 9.003e-275 865.0
SX2_k127_1622477_1 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002314 285.0
SX2_k127_1622477_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004748 260.0
SX2_k127_1622477_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000003974 233.0
SX2_k127_1622477_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000007749 204.0
SX2_k127_1622477_5 HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668 K07015 - - 0.00000000000000000000000000000000000000197 153.0
SX2_k127_1622477_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.0000000000000000000000000000001958 130.0
SX2_k127_1622477_7 ABC-2 family transporter protein - - - 0.0000000000000001861 88.0
SX2_k127_1634341_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000000000000000000000000000000000000000000000001634 192.0
SX2_k127_1634341_1 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000006532 94.0
SX2_k127_1634341_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000003647 83.0
SX2_k127_1634341_3 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - 0.00000005565 62.0
SX2_k127_1639949_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 478.0
SX2_k127_1639949_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 461.0
SX2_k127_1639949_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000229 258.0
SX2_k127_1639949_3 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000004801 201.0
SX2_k127_1653650_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 517.0
SX2_k127_1653650_1 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007875 278.0
SX2_k127_1656756_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.63e-277 872.0
SX2_k127_1656756_1 beta-lactamase domain protein - - - 0.000000000000000000000000000000000008335 141.0
SX2_k127_1683409_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 473.0
SX2_k127_1683409_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000007411 265.0
SX2_k127_1720167_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002603 237.0
SX2_k127_1720167_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA - - - 0.0000000000000000000000000000000000000000000000000000000007952 216.0
SX2_k127_1720167_2 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.0000000000000000000000000000000001849 143.0
SX2_k127_173154_0 Belongs to the CarB family K01955 - 6.3.5.5 3.398e-200 629.0
SX2_k127_173154_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 466.0
SX2_k127_1738501_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 400.0
SX2_k127_1738501_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 404.0
SX2_k127_1738501_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 389.0
SX2_k127_1738501_3 Abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 294.0
SX2_k127_1738501_4 - - - - 0.0000000000000000000000246 117.0
SX2_k127_1738501_5 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000001226 75.0
SX2_k127_1747953_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 631.0
SX2_k127_1747953_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000006653 191.0
SX2_k127_1747953_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00000000000000000000000000000000000000003671 156.0
SX2_k127_1747953_3 acr, cog1399 K07040 - - 0.000000000000000000000000002215 118.0
SX2_k127_1747953_4 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000006941 95.0
SX2_k127_1747953_5 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000005848 82.0
SX2_k127_1758405_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.6e-220 713.0
SX2_k127_1758405_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 320.0
SX2_k127_1758405_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005449 284.0
SX2_k127_1758405_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000002913 268.0
SX2_k127_1758405_4 PFAM Serine dehydratase alpha chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000003726 251.0
SX2_k127_1758405_5 PDZ DHR GLGF domain protein K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000142 240.0
SX2_k127_1758405_6 Rubrerythrin - - - 0.0000000000000000000000000000000000000000008293 172.0
SX2_k127_1758405_7 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000002537 147.0
SX2_k127_1758405_8 PFAM FeoA family protein K04758 - - 0.00000000000001376 77.0
SX2_k127_1795251_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 7.297e-247 780.0
SX2_k127_1795251_1 Rhomboid family K19225 - 3.4.21.105 0.000000006053 64.0
SX2_k127_1828557_0 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 294.0
SX2_k127_1828557_1 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000000363 222.0
SX2_k127_1828557_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000009275 183.0
SX2_k127_1867245_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000344 266.0
SX2_k127_1867245_1 sugar transferase - - - 0.00000000000000000000000000000000000000000000000000001873 192.0
SX2_k127_1867245_2 O-Antigen ligase K18814 - - 0.000000000000000000006766 109.0
SX2_k127_1867245_3 Tetratricopeptide repeat - - - 0.0000000002315 70.0
SX2_k127_1867245_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000209 61.0
SX2_k127_1870439_0 pilus assembly protein ATPase CpaF K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 291.0
SX2_k127_1870439_1 NUBPL iron-transfer P-loop NTPase K02282 - - 0.00000000000000000000000000000000000000000000000000000000147 221.0
SX2_k127_1870439_2 TIGRFAM Flp pilus assembly protein CpaB K02279 - - 0.0000000000008847 78.0
SX2_k127_1870439_3 Putative Flp pilus-assembly TadE/G-like - - - 0.0000001212 58.0
SX2_k127_1873459_0 Type II IV secretion system protein K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 512.0
SX2_k127_1873459_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 476.0
SX2_k127_1873459_2 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 326.0
SX2_k127_1873459_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000002213 162.0
SX2_k127_1874361_0 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001538 291.0
SX2_k127_1874361_1 hemolysin III K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000007323 242.0
SX2_k127_1874361_2 - - - - 0.000000000000000000000000000000000000000000000000001923 191.0
SX2_k127_1874361_3 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress - - - 0.0000000000000000000000000000000000000000001607 168.0
SX2_k127_1874361_4 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000001472 149.0
SX2_k127_1874361_5 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000003884 139.0
SX2_k127_1874361_6 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000002551 103.0
SX2_k127_1874361_7 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000002 100.0
SX2_k127_1874361_8 acetyltransferase - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.00000000001052 77.0
SX2_k127_1933252_0 Anion-transporting ATPase K01551 - 3.6.3.16 1.061e-208 670.0
SX2_k127_1933252_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001406 283.0
SX2_k127_1933252_2 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000002351 254.0
SX2_k127_1933252_3 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000006121 222.0
SX2_k127_1933252_4 Arsenical resistance operon trans-acting repressor arsD - - - 0.00000000000000000000000000001147 121.0
SX2_k127_1933252_5 Transcriptional regulator, ArsR family K03892 - - 0.0000000000001704 74.0
SX2_k127_1944464_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 565.0
SX2_k127_1944464_1 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000143 273.0
SX2_k127_1944464_2 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002407 255.0
SX2_k127_1944464_3 Hydrolase, NUDIX family - - - 0.00000000000001097 79.0
SX2_k127_1944464_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0001765 46.0
SX2_k127_1944464_5 N-acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0002332 50.0
SX2_k127_1960638_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006416 264.0
SX2_k127_1960638_1 zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000001101 214.0
SX2_k127_1960638_2 oligosaccharyl transferase activity - - - 0.000000000000000000000000001687 127.0
SX2_k127_1960638_3 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.000000000000000009943 92.0
SX2_k127_2013163_0 fructose-1,6-bisphosphatase K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 359.0
SX2_k127_2013163_1 Proton-coupled thiamine transporter YuaJ K16789 - - 0.0000000000000000000000000000000000002525 151.0
SX2_k127_2013163_2 heme binding K21471,K21472 - - 0.0000000000000000000000000000001791 143.0
SX2_k127_2013163_3 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.0000000000001367 80.0
SX2_k127_2013163_4 Regulatory protein, FmdB family - - - 0.0000000000001893 78.0
SX2_k127_2013163_5 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000005039 62.0
SX2_k127_2030291_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 404.0
SX2_k127_2030291_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000002456 160.0
SX2_k127_2030291_2 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000003534 132.0
SX2_k127_2030291_3 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000001691 120.0
SX2_k127_2030291_4 - - - - 0.0002758 45.0
SX2_k127_2042975_0 Transcriptional regulator PadR-like family K10947 - - 0.0000000000000006047 81.0
SX2_k127_2042975_1 PilT protein domain protein - - - 0.0000148 54.0
SX2_k127_2042975_2 SpoVT / AbrB like domain K07172 - - 0.00001756 47.0
SX2_k127_2056506_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 415.0
SX2_k127_2056506_1 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000001346 211.0
SX2_k127_2056506_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000001727 203.0
SX2_k127_2056506_3 OsmC-like protein K07397 - - 0.000000000000000000000000000000001352 134.0
SX2_k127_2056506_4 - - - - 0.000000000000009268 87.0
SX2_k127_2089370_0 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 412.0
SX2_k127_2089370_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000004208 180.0
SX2_k127_2089370_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000002239 104.0
SX2_k127_2089370_3 Rieske-like [2Fe-2S] domain K05710 - - 0.000000000000000000534 97.0
SX2_k127_2089370_4 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000001254 91.0
SX2_k127_2089370_5 WYL domain K13573 - - 0.0000000000000009725 88.0
SX2_k127_2089370_6 PFAM glutaredoxin - - - 0.000000000000004582 89.0
SX2_k127_2089370_7 Transcriptional regulator - - - 0.00000000005983 72.0
SX2_k127_2096661_0 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000404 260.0
SX2_k127_2096661_1 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006139 247.0
SX2_k127_2096661_2 short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000241 267.0
SX2_k127_2096661_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000001827 211.0
SX2_k127_2096661_4 TIGRFAM cell envelope-related function transcriptional attenuator common domain - - - 0.000000000000000000000000000000000007227 146.0
SX2_k127_2096661_5 Conserved repeat domain - - - 0.00000007684 63.0
SX2_k127_2175689_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 451.0
SX2_k127_2175689_1 pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 440.0
SX2_k127_2175689_2 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 407.0
SX2_k127_2175689_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001594 281.0
SX2_k127_2175689_4 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000001155 196.0
SX2_k127_2175689_5 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.0000000000000000000000000000001831 133.0
SX2_k127_2175689_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000001252 118.0
SX2_k127_2175689_7 heat shock protein binding - - - 0.00001065 52.0
SX2_k127_2232725_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 410.0
SX2_k127_2232725_1 - - - - 0.0000000000000000000000000000000002251 135.0
SX2_k127_2232725_2 - - - - 0.0000000000008773 77.0
SX2_k127_2232725_3 Belongs to the 5'-nucleotidase family - - - 0.000000002463 69.0
SX2_k127_2232725_4 type IV pilus modification protein PilV - - - 0.00001268 57.0
SX2_k127_2232725_5 - - - - 0.0008646 51.0
SX2_k127_2252310_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 585.0
SX2_k127_2252310_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 487.0
SX2_k127_2252310_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 306.0
SX2_k127_2252310_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000004818 268.0
SX2_k127_2252310_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000001393 166.0
SX2_k127_2252310_5 Preprotein translocase SecG subunit K03075 - - 0.00000000001509 72.0
SX2_k127_2329885_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 388.0
SX2_k127_2329885_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008939 245.0
SX2_k127_2329885_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000004162 159.0
SX2_k127_2329885_3 abc transporter K01990 - - 0.00000000000000000000000007794 115.0
SX2_k127_2329885_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 0.0000000003441 64.0
SX2_k127_2329885_5 Phospholipase_D-nuclease N-terminal - - - 0.000001971 57.0
SX2_k127_2403663_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.521e-320 1004.0
SX2_k127_2403663_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 310.0
SX2_k127_2403663_2 Camelysin metallo-endopeptidase - - - 0.000000002596 66.0
SX2_k127_2403663_3 Peptidase S24-like K13280 - 3.4.21.89 0.0000003902 61.0
SX2_k127_2406256_0 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000003737 199.0
SX2_k127_2406256_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000002613 160.0
SX2_k127_2456147_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 566.0
SX2_k127_2456147_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 426.0
SX2_k127_2456147_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 410.0
SX2_k127_2456147_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000003593 235.0
SX2_k127_2456147_4 NmrA-like family - - - 0.00000000000004377 83.0
SX2_k127_2473974_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07651 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000005483 252.0
SX2_k127_2473974_1 iron-sulfur binding K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000004629 243.0
SX2_k127_2473974_2 Transcriptional regulatory protein, C terminal K02483,K07658 - - 0.0000000000000000000000000000000000000000000000000000000000001251 220.0
SX2_k127_2473974_3 - - - - 0.00000000001627 74.0
SX2_k127_2480200_0 TIGRFAM RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000003935 173.0
SX2_k127_2480200_1 EamA-like transporter family - - - 0.0000000000000000000007761 107.0
SX2_k127_2480200_2 Domain of unknown function DUF302 - - - 0.00000000000000003411 87.0
SX2_k127_2480200_3 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000919 79.0
SX2_k127_2480200_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00001074 57.0
SX2_k127_2480200_5 SMART phosphoesterase PHP domain protein - - - 0.0004395 45.0
SX2_k127_2493810_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000006227 217.0
SX2_k127_2493810_1 QueT transporter - - - 0.00000000000000000000000000000000000000000000000000002273 194.0
SX2_k127_2493810_2 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000002634 192.0
SX2_k127_2493810_3 Domains FehydlgC, FeS, sigma54 interaction, HTH8 - - - 0.00001098 48.0
SX2_k127_2505594_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 586.0
SX2_k127_2505594_1 PFAM Pyruvate carboxyltransferase K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 525.0
SX2_k127_2505594_2 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 489.0
SX2_k127_2505594_3 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000002378 237.0
SX2_k127_2505594_4 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000176 238.0
SX2_k127_2505594_5 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000003129 113.0
SX2_k127_2516892_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000001091 219.0
SX2_k127_2516892_1 DivIVA domain protein K04074 - - 0.000000000000000000000000000212 123.0
SX2_k127_2516892_2 YGGT family K02221 - - 0.000000007954 67.0
SX2_k127_2537736_0 phosphate starvation-inducible protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 413.0
SX2_k127_2537736_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 353.0
SX2_k127_2537736_2 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000087 266.0
SX2_k127_2537736_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000002608 201.0
SX2_k127_2537736_4 Transporter associated domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000001768 199.0
SX2_k127_2537736_5 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.00000000000000000000000000000000000000000000000001807 187.0
SX2_k127_2537736_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000205 172.0
SX2_k127_2537736_7 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000001431 135.0
SX2_k127_2537736_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000001187 121.0
SX2_k127_2560059_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1144.0
SX2_k127_2560059_1 ComEA protein K02237 - - 0.00000000000000000000000000000000001373 144.0
SX2_k127_2560059_2 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000000000000004838 89.0
SX2_k127_2564754_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001493 270.0
SX2_k127_2564754_1 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.000000000000000000000000009464 124.0
SX2_k127_2564754_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000007677 104.0
SX2_k127_2564754_3 response regulator - - - 0.000000000000000000000001596 115.0
SX2_k127_2564754_4 PFAM H -transporting two-sector ATPase, C (AC39) subunit K02119 - - 0.0000000000000000003791 99.0
SX2_k127_2564754_5 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000002376 81.0
SX2_k127_2564754_7 ATP synthase, subunit F K02122 - - 0.0000007266 57.0
SX2_k127_2578595_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000002427 235.0
SX2_k127_2578595_1 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000001127 198.0
SX2_k127_2719257_0 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 417.0
SX2_k127_2719257_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000001503 178.0
SX2_k127_2719257_2 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000007171 161.0
SX2_k127_2719257_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000002966 131.0
SX2_k127_2719257_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000005466 117.0
SX2_k127_2719257_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000003695 76.0
SX2_k127_2726401_0 metallopeptidase activity K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 374.0
SX2_k127_2726401_1 NLP P60 protein K21471 - - 0.00000000000000000000000000000000000000000001107 176.0
SX2_k127_2741400_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 571.0
SX2_k127_2741400_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 402.0
SX2_k127_2741400_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 383.0
SX2_k127_2741400_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000002093 255.0
SX2_k127_2741400_4 Cytochrome b/b6/petB K03620 - - 0.00000000000000000000000000000000000000000000000000000000000002745 220.0
SX2_k127_2741400_5 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000004953 169.0
SX2_k127_2741400_6 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000006114 128.0
SX2_k127_2741400_7 Cytochrome b5-like Heme/Steroid binding domain - - - 0.0000000000000000009032 90.0
SX2_k127_2764944_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 404.0
SX2_k127_2764944_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000007934 190.0
SX2_k127_2764944_2 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000004175 170.0
SX2_k127_2764944_3 Molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.0000000000000000000000000000000000002096 152.0
SX2_k127_2764944_4 PFAM MOSC domain containing protein - - - 0.0000000000000000000000003291 106.0
SX2_k127_2764944_5 Mo-molybdopterin cofactor biosynthetic process - - - 0.0001015 53.0
SX2_k127_2846424_0 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 471.0
SX2_k127_2846424_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000003575 149.0
SX2_k127_3039688_0 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000242 226.0
SX2_k127_3039688_1 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000008418 136.0
SX2_k127_3039688_2 Alpha beta hydrolase - - - 0.000000000000000000004975 103.0
SX2_k127_3039688_3 general secretion pathway protein - - - 0.00008218 50.0
SX2_k127_3049583_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000009619 146.0
SX2_k127_3049583_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000597 110.0
SX2_k127_3049583_2 NACHT domain - - - 0.000000000000000002262 99.0
SX2_k127_3049583_3 protein folding in endoplasmic reticulum K19134 - - 0.0000000005634 70.0
SX2_k127_3071053_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 7.873e-212 679.0
SX2_k127_3071053_1 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000002169 252.0
SX2_k127_3071053_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000001303 220.0
SX2_k127_3071053_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000003263 188.0
SX2_k127_3071053_4 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000001599 133.0
SX2_k127_3074166_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 608.0
SX2_k127_3074166_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 399.0
SX2_k127_3074166_2 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000005965 141.0
SX2_k127_3077698_0 Cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 479.0
SX2_k127_3077698_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 469.0
SX2_k127_3077698_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000005403 198.0
SX2_k127_3077698_3 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000003729 188.0
SX2_k127_3077698_4 Belongs to the SEDS family K05837 - - 0.00000000000006612 76.0
SX2_k127_3077698_5 rod shape-determining protein MreD K03571 - - 0.0000000000001291 79.0
SX2_k127_3082780_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 556.0
SX2_k127_3082780_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 489.0
SX2_k127_3082780_2 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000056 199.0
SX2_k127_3082780_3 phosphorelay signal transduction system K07658 - - 0.00000000000000000000000002215 117.0
SX2_k127_3082780_4 PFAM Acetyltransferase (GNAT) family - - - 0.000000000003105 78.0
SX2_k127_3082780_5 - - - - 0.0000003835 57.0
SX2_k127_3095645_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 401.0
SX2_k127_3095645_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 306.0
SX2_k127_3095645_2 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002168 282.0
SX2_k127_3095645_3 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000000002389 146.0
SX2_k127_3095645_4 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000158 114.0
SX2_k127_3096046_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 507.0
SX2_k127_3096046_1 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 497.0
SX2_k127_3096046_2 NIL domain - - - 0.000000000000000000000002994 105.0
SX2_k127_3132360_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 453.0
SX2_k127_3132360_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 346.0
SX2_k127_3132360_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 308.0
SX2_k127_3132360_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001432 272.0
SX2_k127_3139495_0 Glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 309.0
SX2_k127_3139495_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005027 266.0
SX2_k127_3139495_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000008 217.0
SX2_k127_3139495_3 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000004025 134.0
SX2_k127_3141433_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001592 261.0
SX2_k127_3141433_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000009175 190.0
SX2_k127_3141433_2 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000001169 127.0
SX2_k127_3141433_3 Sortase family - - - 0.000000000000000000000000004932 119.0
SX2_k127_3163062_0 Conserved region in glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 393.0
SX2_k127_3163062_1 DHHA2 domain protein K15986 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 339.0
SX2_k127_3163062_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000001206 183.0
SX2_k127_3163062_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000005013 90.0
SX2_k127_3191748_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 490.0
SX2_k127_3191748_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 468.0
SX2_k127_3191748_2 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 321.0
SX2_k127_3191748_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001284 280.0
SX2_k127_3191748_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000002732 237.0
SX2_k127_3191748_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000004368 234.0
SX2_k127_3191748_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000001777 190.0
SX2_k127_3191748_7 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000000000008549 191.0
SX2_k127_3191748_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000001145 168.0
SX2_k127_3191748_9 prepilin-type N-terminal cleavage methylation domain K02456,K02650 - - 0.0000004615 59.0
SX2_k127_3281819_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 469.0
SX2_k127_3281819_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 365.0
SX2_k127_3281819_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000000002411 145.0
SX2_k127_3281819_11 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000004648 131.0
SX2_k127_3281819_12 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000003576 77.0
SX2_k127_3281819_13 Ribosomal protein L30p/L7e K02907 - - 0.0000000004214 60.0
SX2_k127_3281819_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 321.0
SX2_k127_3281819_3 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 304.0
SX2_k127_3281819_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000011 274.0
SX2_k127_3281819_5 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002316 254.0
SX2_k127_3281819_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000003666 232.0
SX2_k127_3281819_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000003799 203.0
SX2_k127_3281819_8 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000005739 197.0
SX2_k127_3281819_9 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16787 - - 0.000000000000000000000000000000000000000105 168.0
SX2_k127_329219_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 2.293e-196 634.0
SX2_k127_329219_1 DAK2 domain fusion protein YloV K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 496.0
SX2_k127_329219_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000001951 196.0
SX2_k127_329219_3 PFAM Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000003415 194.0
SX2_k127_329219_4 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000008331 121.0
SX2_k127_329219_5 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000002941 121.0
SX2_k127_329219_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000008359 99.0
SX2_k127_329219_7 Hydrid cluster protein-associated redox disulfide domain protein - - - 0.00007258 52.0
SX2_k127_3311649_0 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000000005419 164.0
SX2_k127_3311649_1 phosphatase activity K07025 - - 0.000000000000000000000000000000194 134.0
SX2_k127_3311649_2 sigma factor antagonist activity K03409,K05946,K06379 GO:0000003,GO:0000287,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004035,GO:0005488,GO:0005515,GO:0006355,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016989,GO:0019219,GO:0019222,GO:0019954,GO:0030145,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0043934,GO:0044237,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.4.1.187,2.7.11.1 0.0000000000000000000000000000003637 133.0
SX2_k127_3311649_3 PFAM Nitroreductase - - - 0.00000000000000000000000000005172 124.0
SX2_k127_3311649_4 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase K03429 - 2.4.1.315 0.000000003816 68.0
SX2_k127_3311956_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 602.0
SX2_k127_3311956_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006617 283.0
SX2_k127_3311956_2 VanW like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000598 238.0
SX2_k127_3313046_0 Chemotaxis protein CheA K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 456.0
SX2_k127_3313046_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000005734 274.0
SX2_k127_3313046_2 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000001145 224.0
SX2_k127_3313046_3 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000009563 163.0
SX2_k127_3313046_4 Chemotaxis protein CheC K03410 - - 0.00000000000000000000000000000000000213 149.0
SX2_k127_3313046_5 Chemotaxis signal transduction protein K03408 - - 0.0000000000000000000000000008373 121.0
SX2_k127_3313046_6 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000002702 50.0
SX2_k127_3320374_0 ABC transporter K02006,K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 288.0
SX2_k127_3320374_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001591 284.0
SX2_k127_3320374_2 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000000000001636 200.0
SX2_k127_3320374_3 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000003871 178.0
SX2_k127_3320374_4 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000009987 142.0
SX2_k127_3320374_5 Cobalt ABC transporter K02008 - - 0.0000000000000000000000000004583 131.0
SX2_k127_3320374_6 SMART Nucleotide binding protein, PINc K07175 - - 0.0001728 53.0
SX2_k127_3382886_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 419.0
SX2_k127_3382886_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 295.0
SX2_k127_3382886_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000002738 276.0
SX2_k127_3382886_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.0000000000000000000000000000000000000000000000000000000000000009236 239.0
SX2_k127_3382886_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000007809 204.0
SX2_k127_3382886_5 Beta-lactamase - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.0000000003247 66.0
SX2_k127_3382886_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.000207 52.0
SX2_k127_338991_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 608.0
SX2_k127_338991_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000003074 94.0
SX2_k127_3422269_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 557.0
SX2_k127_3422269_1 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 413.0
SX2_k127_3422269_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000001927 236.0
SX2_k127_3422269_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000006282 186.0
SX2_k127_3422269_4 Virulence activator alpha C-term - - - 0.0000000000000000000000000000000001588 140.0
SX2_k127_3422269_5 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000003595 128.0
SX2_k127_3422269_6 Serine aminopeptidase, S33 - - - 0.00007302 46.0
SX2_k127_3433347_0 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 348.0
SX2_k127_3433347_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 332.0
SX2_k127_3433347_2 Diguanylate cyclase - - - 0.00000000000000000000000000000002677 141.0
SX2_k127_3439158_0 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000001739 170.0
SX2_k127_3445171_0 DNA topoisomerase K03168 - 5.99.1.2 1.411e-273 872.0
SX2_k127_3445171_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 441.0
SX2_k127_3445171_10 Twin arginine-targeting protein translocase, TatA E family K03117,K03646 - - 0.000007015 53.0
SX2_k127_3445171_11 peptidyl-tyrosine sulfation - - - 0.00007518 53.0
SX2_k127_3445171_12 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0005181 51.0
SX2_k127_3445171_2 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 291.0
SX2_k127_3445171_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 292.0
SX2_k127_3445171_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000008729 236.0
SX2_k127_3445171_5 PFAM Metal-dependent phosphohydrolase, HD K06951 - - 0.0000000000000000000000000000000000000000000000000005829 190.0
SX2_k127_3445171_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000002419 192.0
SX2_k127_3445171_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000002103 136.0
SX2_k127_3445171_8 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000002962 124.0
SX2_k127_3445171_9 antisigma factor binding K04749,K17763,K20978 - - 0.000001247 56.0
SX2_k127_3469933_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.964e-305 945.0
SX2_k127_3469933_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000002971 127.0
SX2_k127_3532287_0 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 366.0
SX2_k127_3532287_1 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 355.0
SX2_k127_3532287_2 ATP-grasp domain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000003348 187.0
SX2_k127_3532287_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000002986 137.0
SX2_k127_3532287_4 Glycosyl transferases group 1 K19424 - - 0.0000000000000000000000000004282 121.0
SX2_k127_3567292_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 576.0
SX2_k127_3567292_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000004565 178.0
SX2_k127_3567292_2 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000006395 143.0
SX2_k127_3578333_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 612.0
SX2_k127_3578333_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000004055 194.0
SX2_k127_3578333_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000000000007768 86.0
SX2_k127_3650035_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 423.0
SX2_k127_3650035_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 387.0
SX2_k127_3650035_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 333.0
SX2_k127_3650035_3 NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000001041 72.0
SX2_k127_3650035_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000001658 59.0
SX2_k127_3673957_0 Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 6.301e-238 743.0
SX2_k127_3673957_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 517.0
SX2_k127_3673957_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 396.0
SX2_k127_3673957_3 Isochorismatase family K09020 - 3.5.1.110 0.000000000000000000000000000000000000000000000000000000000000000000000000000001663 274.0
SX2_k127_3673957_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000001171 253.0
SX2_k127_3673957_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000001948 220.0
SX2_k127_3673957_6 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000006821 198.0
SX2_k127_3673957_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000001086 55.0
SX2_k127_387490_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 8.838e-220 700.0
SX2_k127_387490_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 482.0
SX2_k127_3890055_0 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 340.0
SX2_k127_3890055_1 diacylglycerol kinase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000005273 235.0
SX2_k127_3890055_2 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000493 197.0
SX2_k127_3894520_0 TIGRFAM histidinol phosphate phosphatase HisJ K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000004906 277.0
SX2_k127_3894520_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000001333 218.0
SX2_k127_3894520_2 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000002918 206.0
SX2_k127_3894520_3 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.0000000000000000000000000000000000004265 147.0
SX2_k127_3894520_4 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000007296 130.0
SX2_k127_3894520_5 zinc ribbon domain K07164 - - 0.0000000000000000000000007711 113.0
SX2_k127_3982088_0 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 297.0
SX2_k127_3982088_1 Psort location CytoplasmicMembrane, score 9.46 K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000009142 196.0
SX2_k127_3982088_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000001432 172.0
SX2_k127_3982088_3 metal cluster binding - - - 0.000000000001312 75.0
SX2_k127_4094345_0 alpha beta alpha domain I K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 516.0
SX2_k127_4214508_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 1.473e-250 809.0
SX2_k127_4214508_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 490.0
SX2_k127_4214508_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 376.0
SX2_k127_4214508_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 329.0
SX2_k127_4214508_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 324.0
SX2_k127_4214508_5 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.000000000000000000000000000004504 123.0
SX2_k127_4242335_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000215 129.0
SX2_k127_4242335_1 Belongs to the SAICAR synthetase family K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.00000002713 57.0
SX2_k127_4242335_2 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K07025 - - 0.00000109 51.0
SX2_k127_4259448_0 MviN-like protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 338.0
SX2_k127_4259448_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000001141 233.0
SX2_k127_4266358_0 Glycosyltransferase 36 associated - - - 1.478e-292 943.0
SX2_k127_4266358_1 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000109 138.0
SX2_k127_4266358_2 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000001313 124.0
SX2_k127_4266358_3 Thioredoxin-like protein HCF164, chloroplastic - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009636,GO:0009987,GO:0010190,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0017004,GO:0019725,GO:0022607,GO:0031976,GO:0031977,GO:0031984,GO:0033554,GO:0034357,GO:0034599,GO:0034622,GO:0042221,GO:0042592,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055035,GO:0055114,GO:0065003,GO:0065007,GO:0065008,GO:0070887,GO:0071840,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000002064 58.0
SX2_k127_434743_0 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000006925 150.0
SX2_k127_434743_1 sequence-specific DNA binding K13655 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000005718 89.0
SX2_k127_434743_2 domain, Protein - - - 0.00000001116 63.0
SX2_k127_43599_0 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 378.0
SX2_k127_43599_1 cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 356.0
SX2_k127_43599_2 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 320.0
SX2_k127_43599_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000001802 246.0
SX2_k127_43599_4 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.000004704 52.0
SX2_k127_43599_5 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564 3.4.21.102 0.0001568 48.0
SX2_k127_4364518_0 RNA polymerase sigma-70 factor, sigma-B F G subfamily K03090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009276 305.0
SX2_k127_4364518_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000527 202.0
SX2_k127_4364518_2 - K04757 - 2.7.11.1 0.0000000000000002993 89.0
SX2_k127_4364518_3 Bacterial protein of unknown function (DUF948) - - - 0.0000156 51.0
SX2_k127_442549_0 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000001034 240.0
SX2_k127_442549_1 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000007028 154.0
SX2_k127_442549_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 - 0.0000000000000000000000000000000000000003858 171.0
SX2_k127_454133_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000003962 231.0
SX2_k127_454133_1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000635 240.0
SX2_k127_454133_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000003892 162.0
SX2_k127_454133_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.000000000000000000000000000000000006732 147.0
SX2_k127_454133_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000001758 140.0
SX2_k127_4552285_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 463.0
SX2_k127_4552285_1 PFAM Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 433.0
SX2_k127_4552285_2 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000001613 245.0
SX2_k127_4552285_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000001898 147.0
SX2_k127_4554193_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 7.401e-232 730.0
SX2_k127_4554193_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070,K03789,K14742 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004596,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006464,GO:0006473,GO:0006474,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008999,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0030312,GO:0031365,GO:0032991,GO:0034212,GO:0034470,GO:0034641,GO:0034660,GO:0036211,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051604,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.128,2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 471.0
SX2_k127_4554193_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000008299 166.0
SX2_k127_4554193_3 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.00000000000000000000000000000000000000008932 155.0
SX2_k127_4554193_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000003079 147.0
SX2_k127_4554193_5 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.00000000000000000000000000001643 125.0
SX2_k127_4620253_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1065.0
SX2_k127_4620253_1 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.000000000000000000000000000000000000000000000000333 189.0
SX2_k127_4620253_2 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.000000000000000000000000000002563 134.0
SX2_k127_4625183_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 330.0
SX2_k127_4625183_1 Phosphate transport system permease protein PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 344.0
SX2_k127_4625183_2 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000001808 228.0
SX2_k127_4625183_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000002023 217.0
SX2_k127_4625183_4 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000000000001085 168.0
SX2_k127_4631045_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 494.0
SX2_k127_4631045_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 421.0
SX2_k127_4631045_10 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000001298 186.0
SX2_k127_4631045_11 PFAM response regulator receiver K07657 - - 0.0000000000000000000006917 102.0
SX2_k127_4631045_12 RIP metalloprotease RseP K11749 - - 0.00000000000000000003814 93.0
SX2_k127_4631045_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 341.0
SX2_k127_4631045_3 Sigma-70, region 4 K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 323.0
SX2_k127_4631045_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 323.0
SX2_k127_4631045_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005011 283.0
SX2_k127_4631045_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000006303 274.0
SX2_k127_4631045_7 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003996 273.0
SX2_k127_4631045_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000001783 222.0
SX2_k127_4631045_9 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000001625 194.0
SX2_k127_4634291_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 452.0
SX2_k127_4634291_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 421.0
SX2_k127_4634291_2 Polysaccharide biosynthesis protein K17716 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 398.0
SX2_k127_4634291_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000002045 194.0
SX2_k127_4634291_4 Glycosyl transferases group 1 - - - 0.000000000000000000003182 106.0
SX2_k127_4662423_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 339.0
SX2_k127_4662423_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000001465 209.0
SX2_k127_4662423_2 response regulator receiver K07696,K11624 - - 0.0000000000000000000000000000000000001183 150.0
SX2_k127_4662423_3 Histidine kinase - - - 0.00000000000000000000000000000009195 141.0
SX2_k127_4662423_4 PFAM Amino acid-binding ACT - - - 0.000000006694 62.0
SX2_k127_4714898_0 TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 444.0
SX2_k127_4714898_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000002049 246.0
SX2_k127_4714898_2 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000002438 141.0
SX2_k127_4718325_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 3.165e-287 912.0
SX2_k127_4718325_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000002863 191.0
SX2_k127_4832936_0 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 307.0
SX2_k127_4832936_1 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000008557 175.0
SX2_k127_4832936_2 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000001667 158.0
SX2_k127_4837596_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.028e-249 781.0
SX2_k127_4845146_0 TIGRFAM Arsenical-resistance protein K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 462.0
SX2_k127_4845146_1 - - - - 0.0000000000000000000000000001147 127.0
SX2_k127_4845146_2 SMART regulatory protein ArsR K03892 - - 0.000000000000000001585 92.0
SX2_k127_4845146_3 Universal stress protein family - - - 0.0000000004444 72.0
SX2_k127_4845146_4 Helix-turn-helix domain - - - 0.000004515 58.0
SX2_k127_487368_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 558.0
SX2_k127_487368_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 432.0
SX2_k127_487368_2 - - - - 0.00000000000000000000000000000000001189 141.0
SX2_k127_487368_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000002176 87.0
SX2_k127_487368_4 - - - - 0.0001344 46.0
SX2_k127_4875951_0 type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000004466 218.0
SX2_k127_4875951_1 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000002707 205.0
SX2_k127_4875951_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02658 - - 0.00000000000000000000000000001231 122.0
SX2_k127_4875951_3 Two component signalling adaptor domain K03408 - - 0.0000000000000000001258 96.0
SX2_k127_4875951_4 Two component signalling adaptor domain K03408 - - 0.000000000000001009 89.0
SX2_k127_4875951_5 PFAM MCP methyltransferase, CheR-type K00575 - 2.1.1.80 0.0000004377 55.0
SX2_k127_4940873_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K13019 - 5.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 435.0
SX2_k127_4940873_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 397.0
SX2_k127_4940873_2 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 306.0
SX2_k127_4940873_3 PFAM transferase hexapeptide repeat containing protein - - - 0.0000000000000000000000000000000007154 132.0
SX2_k127_4941897_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 403.0
SX2_k127_4941897_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000005201 95.0
SX2_k127_4943150_0 GTP-binding protein TypA K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 288.0
SX2_k127_4943150_1 Putative sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001079 288.0
SX2_k127_4943150_2 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000007203 199.0
SX2_k127_4943150_3 PadR family transcriptional regulator K10947 - - 0.000000000000000000000000000000000000004661 149.0
SX2_k127_4943150_4 membrane - - - 0.000000000000000000118 99.0
SX2_k127_4943150_5 Phospholipase_D-nuclease N-terminal - - - 0.0002282 50.0
SX2_k127_4970256_0 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000002183 211.0
SX2_k127_4970256_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000007476 195.0
SX2_k127_500464_0 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001051 282.0
SX2_k127_500464_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000009043 136.0
SX2_k127_500464_2 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000001702 133.0
SX2_k127_500464_3 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000005691 93.0
SX2_k127_5023803_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002466 260.0
SX2_k127_5023803_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003726 251.0
SX2_k127_5023803_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000007864 186.0
SX2_k127_5023803_3 ABC transporter K01995 - - 0.0000000000000000000000000000000000007282 156.0
SX2_k127_5023803_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000001874 71.0
SX2_k127_5043510_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000002118 273.0
SX2_k127_5043510_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000007039 184.0
SX2_k127_5043510_2 Ribosomal protein L19 K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000000000001043 170.0
SX2_k127_5043510_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000006421 171.0
SX2_k127_5043510_4 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000006684 110.0
SX2_k127_5043510_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000002137 81.0
SX2_k127_5055966_0 Bacterial protein of unknown function (DUF853) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 618.0
SX2_k127_5055966_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007785 271.0
SX2_k127_5055966_2 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000001496 208.0
SX2_k127_5283473_0 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 526.0
SX2_k127_5283473_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009322 288.0
SX2_k127_5283473_2 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000327 280.0
SX2_k127_5283473_3 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000001338 259.0
SX2_k127_5283473_4 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000001335 188.0
SX2_k127_5283473_5 endonuclease III K03575 - - 0.0000000000000000000006219 98.0
SX2_k127_5283473_6 Protein of unknown function (DUF4446) - - - 0.0000000000001699 79.0
SX2_k127_5287633_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.65e-227 722.0
SX2_k127_5287633_1 Thiamine pyrophosphokinase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 424.0
SX2_k127_5287633_2 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 381.0
SX2_k127_5287633_3 integral membrane protein MviN K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 366.0
SX2_k127_5287633_4 TIGRFAM hemolysin TlyA family protein K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000003748 267.0
SX2_k127_5287633_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000002856 229.0
SX2_k127_5287633_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000003889 159.0
SX2_k127_5287633_7 Copper transport outer membrane protein, MctB - - - 0.00000000444 67.0
SX2_k127_536152_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 333.0
SX2_k127_5407373_0 Clp domain protein K03696 - - 0.0 1016.0
SX2_k127_5407373_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 487.0
SX2_k127_5407373_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 400.0
SX2_k127_5407373_3 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation K07067 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 333.0
SX2_k127_5407373_4 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000004234 263.0
SX2_k127_5407373_5 PilT protein domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002544 267.0
SX2_k127_5407373_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000003149 212.0
SX2_k127_5407373_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000003082 126.0
SX2_k127_5407373_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000004855 100.0
SX2_k127_5425330_0 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 303.0
SX2_k127_5425330_1 chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000003306 208.0
SX2_k127_5425330_2 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000001401 149.0
SX2_k127_5425330_3 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000006875 82.0
SX2_k127_5542890_0 - - - - 0.000000000000000000000000000000000000000000000000000000000003374 213.0
SX2_k127_5542890_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000002197 186.0
SX2_k127_5542890_2 domain, Protein - - - 0.000000000000000000000000000000261 141.0
SX2_k127_5542890_3 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000002425 123.0
SX2_k127_5542890_5 aminopeptidase activity - - - 0.00000000000000008337 94.0
SX2_k127_5542890_6 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.0000000000000001211 81.0
SX2_k127_5542890_7 TIGRFAM integral membrane protein TIGR01906 - - - 0.00000000000001726 83.0
SX2_k127_5542890_8 Transcriptional regulator, Crp Fnr family K10914,K21563 - - 0.00000004122 63.0
SX2_k127_5553562_0 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 305.0
SX2_k127_5553562_1 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001058 281.0
SX2_k127_5553562_2 Fumarase C-terminus K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000001798 209.0
SX2_k127_5553562_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000002035 210.0
SX2_k127_5553562_4 Fumarate hydratase (Fumerase) K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000002693 191.0
SX2_k127_5553562_5 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000001504 135.0
SX2_k127_5553562_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000001541 134.0
SX2_k127_5553562_7 response to nickel cation - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0040008,GO:0045926,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0065007,GO:0097159,GO:1901363 - 0.00000000000002569 77.0
SX2_k127_5565821_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0008150,GO:0040007 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 370.0
SX2_k127_5565821_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000002321 219.0
SX2_k127_5565821_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000003453 170.0
SX2_k127_5591410_0 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000009137 185.0
SX2_k127_5591410_1 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000007902 146.0
SX2_k127_5591410_2 B12 binding domain - - - 0.00000000000000000000003114 108.0
SX2_k127_5591410_4 Protein of unknown function (DUF1048) - - - 0.0005888 47.0
SX2_k127_5671386_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 608.0
SX2_k127_5671386_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 576.0
SX2_k127_5671386_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000003816 143.0
SX2_k127_5671386_3 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.00000000000000000000000000001313 132.0
SX2_k127_5748176_0 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 629.0
SX2_k127_5748176_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 300.0
SX2_k127_5748176_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000314 273.0
SX2_k127_5756450_0 ABC transporter, ATP-binding protein K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 443.0
SX2_k127_5756450_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 379.0
SX2_k127_5756450_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 321.0
SX2_k127_5756450_3 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000001503 143.0
SX2_k127_5756450_4 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000009311 117.0
SX2_k127_5767611_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001861 284.0
SX2_k127_5767611_1 TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000191 265.0
SX2_k127_5767611_10 - - - - 0.0000000000001503 75.0
SX2_k127_5767611_11 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000166 52.0
SX2_k127_5767611_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000005119 201.0
SX2_k127_5767611_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.0000000000000000000000000000000000000000000000007505 187.0
SX2_k127_5767611_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000002328 169.0
SX2_k127_5767611_5 NLP P60 protein K21471 - - 0.0000000000000000000000000000000000000002173 168.0
SX2_k127_5767611_6 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.00000000000000000000000000000000000001347 149.0
SX2_k127_5767611_7 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000002853 142.0
SX2_k127_5767611_8 zinc-ribbon domain - - - 0.000000000000000000000000001779 117.0
SX2_k127_5767611_9 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000001312 111.0
SX2_k127_5777826_0 elongation factor G K02355 - - 6.154e-260 821.0
SX2_k127_5777826_1 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 409.0
SX2_k127_5777826_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 346.0
SX2_k127_5777826_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000001005 199.0
SX2_k127_5777826_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000001812 192.0
SX2_k127_5777826_5 Diacylglycerol kinase catalytic domain K07029 - 2.7.1.107 0.000000000000000000000000000000000000000000000005156 184.0
SX2_k127_5777826_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000002236 145.0
SX2_k127_5800937_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 599.0
SX2_k127_5800937_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000001259 227.0
SX2_k127_5800937_2 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000004475 207.0
SX2_k127_5800937_3 TIGRFAM cell envelope-related function transcriptional attenuator - - - 0.0000000000000000000000000000000000000000000000000000006184 209.0
SX2_k127_5800937_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000003069 110.0
SX2_k127_5800937_5 PFAM O-antigen polymerase - - - 0.0000000000004025 83.0
SX2_k127_5800937_6 TIGRFAM cell envelope-related function transcriptional attenuator - - - 0.00001336 48.0
SX2_k127_5822514_0 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 439.0
SX2_k127_5822514_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 410.0
SX2_k127_5822514_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 366.0
SX2_k127_5822514_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 364.0
SX2_k127_5822514_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 361.0
SX2_k127_5822514_5 PASTA domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 305.0
SX2_k127_5822514_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003452 280.0
SX2_k127_5822514_7 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002764 280.0
SX2_k127_588531_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 325.0
SX2_k127_588531_1 PFAM DRTGG domain protein K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000004115 238.0
SX2_k127_588531_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000401 153.0
SX2_k127_5895904_0 Heat shock 70 kDa protein K04043 - - 5.528e-301 933.0
SX2_k127_5895904_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.263e-299 940.0
SX2_k127_5895904_2 NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000004452 247.0
SX2_k127_5895904_3 sortase family K07284 - 3.4.22.70 0.000000000000000000000000008085 122.0
SX2_k127_5895904_4 4Fe-4S binding domain - - - 0.0000000000000000006188 91.0
SX2_k127_5895904_5 - - - - 0.000000002269 68.0
SX2_k127_5912093_0 Fibronectin type 3 domain K20276 - - 0.00000000000000000000000006188 126.0
SX2_k127_5912093_1 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000002987 120.0
SX2_k127_5912093_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000632 86.0
SX2_k127_5978625_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 562.0
SX2_k127_5978625_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 435.0
SX2_k127_5978625_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000001756 214.0
SX2_k127_5978625_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000001075 180.0
SX2_k127_5978625_4 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000001295 116.0
SX2_k127_5981794_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002532 251.0
SX2_k127_5981794_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000003227 199.0
SX2_k127_5981794_2 WHG domain - - - 0.0000000000000000009147 94.0
SX2_k127_5981794_3 PFAM CAAX amino terminal protease family K07052 - - 0.000000000002677 80.0
SX2_k127_5981794_4 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000003851 79.0
SX2_k127_5981794_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00004636 56.0
SX2_k127_5984307_0 Telomere recombination K04656 - - 4.129e-221 711.0
SX2_k127_5984307_1 hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 463.0
SX2_k127_5984307_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 440.0
SX2_k127_5984307_3 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 447.0
SX2_k127_5984307_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 355.0
SX2_k127_5984307_5 hydrogenase assembly chaperone HypC HupF K04653 - - 0.0000000000000000001328 92.0
SX2_k127_5984307_6 EamA-like transporter family - - - 0.0000000000000000009268 97.0
SX2_k127_6029744_0 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 347.0
SX2_k127_6029744_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 354.0
SX2_k127_6029744_2 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 305.0
SX2_k127_6029744_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000007691 149.0
SX2_k127_6029744_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000006193 117.0
SX2_k127_6029744_5 Transcriptional regulator, TraR DksA family K06204 - - 0.00000000000000002326 88.0
SX2_k127_6029744_6 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000003669 65.0
SX2_k127_612364_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000004062 207.0
SX2_k127_612364_1 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000006963 133.0
SX2_k127_615860_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000009723 236.0
SX2_k127_615860_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000002988 158.0
SX2_k127_615860_2 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0001999 50.0
SX2_k127_676211_0 PFAM zinc iron permease K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006443 283.0
SX2_k127_676211_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000002087 159.0
SX2_k127_676211_2 Transmembrane secretion effector - - - 0.00000001997 65.0
SX2_k127_710972_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.39e-215 686.0
SX2_k127_710972_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.124e-212 667.0
SX2_k127_710972_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 408.0
SX2_k127_710972_3 May be required for sporulation K09762 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 380.0
SX2_k127_710972_4 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 299.0
SX2_k127_710972_5 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005124 253.0
SX2_k127_710972_6 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000004364 87.0
SX2_k127_752329_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 4.95e-213 674.0
SX2_k127_752329_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 533.0
SX2_k127_752329_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 474.0
SX2_k127_752329_3 DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 339.0
SX2_k127_752329_4 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 317.0
SX2_k127_752329_5 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000001775 173.0
SX2_k127_752329_6 Chorismate mutase type II - - - 0.000000000000000000006024 96.0
SX2_k127_755292_0 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 562.0
SX2_k127_755292_1 PFAM LOR SDH bifunctional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 367.0
SX2_k127_758950_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 581.0
SX2_k127_758950_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 406.0
SX2_k127_758950_10 Antidote-toxin recognition MazE, bacterial antitoxin K06284 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0042802,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - 0.000000000000000000008261 96.0
SX2_k127_758950_11 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360 2.1.1.198 0.00001476 48.0
SX2_k127_758950_2 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007063 258.0
SX2_k127_758950_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000002515 227.0
SX2_k127_758950_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - - 0.000000000000000000000000000000000000000000001651 177.0
SX2_k127_758950_5 G5 domain protein - - - 0.0000000000000000000000000000000000000000007668 172.0
SX2_k127_758950_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000003433 153.0
SX2_k127_758950_7 Flavodoxin-like fold - - - 0.000000000000000000000000002316 127.0
SX2_k127_758950_8 Biofilm formation stimulator VEG - - - 0.00000000000000000000003578 101.0
SX2_k127_758950_9 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation K06412 GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - 0.0000000000000000000000836 104.0
SX2_k127_765596_0 fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003241 287.0
SX2_k127_765596_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000002854 224.0
SX2_k127_765596_2 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000001108 185.0
SX2_k127_765596_3 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 0.000000000000000000000000000000000000000008703 156.0
SX2_k127_765596_4 TrpR family protein YerC YecD - - - 0.00000000000000000000000003736 110.0
SX2_k127_770158_0 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000003347 201.0
SX2_k127_770158_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000001101 198.0
SX2_k127_770158_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000829 151.0
SX2_k127_770158_3 Hydrolase, NUDIX family - - - 0.000000000005334 73.0
SX2_k127_770158_4 Lysin motif - - - 0.0004775 50.0
SX2_k127_77921_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 467.0
SX2_k127_77921_1 DNA recombination K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 408.0
SX2_k127_77921_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 303.0
SX2_k127_77921_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000009395 238.0
SX2_k127_77921_4 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000000000002037 163.0
SX2_k127_77921_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000248 119.0
SX2_k127_77921_6 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.0000000000009361 74.0
SX2_k127_780931_0 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571 - 4.1.1.3 2.47e-268 837.0
SX2_k127_780931_1 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 598.0
SX2_k127_780931_2 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002481 289.0
SX2_k127_780931_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005093 257.0
SX2_k127_780931_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000009522 185.0
SX2_k127_780931_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000006114 141.0
SX2_k127_780931_6 3-dehydroquinate synthase K01735 - 4.2.3.4 0.0000000000000000000000000001641 119.0
SX2_k127_780931_7 Asp23 family, cell envelope-related function - - - 0.0000000000000000002049 92.0
SX2_k127_780931_8 Exonuclease VII small subunit - - - 0.0001238 49.0
SX2_k127_82547_0 TIGRFAM DNA polymerase III, alpha subunit K02337,K14162 - 2.7.7.7 3.864e-227 743.0
SX2_k127_850130_0 Two component signalling adaptor domain K03407,K13490 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 446.0
SX2_k127_850130_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 340.0
SX2_k127_850130_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412,K13491 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000003499 276.0
SX2_k127_850130_3 chemotaxis, protein K03406 - - 0.000000000000000000000000000001773 126.0
SX2_k127_854635_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 463.0
SX2_k127_854635_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 466.0
SX2_k127_854635_2 PFAM 2-nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 362.0
SX2_k127_854635_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000008284 183.0
SX2_k127_854635_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000189 111.0
SX2_k127_854635_5 TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase K00059 - 1.1.1.100 0.00000000001485 65.0
SX2_k127_881352_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 425.0
SX2_k127_881352_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 387.0
SX2_k127_881352_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 354.0
SX2_k127_881352_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003525 252.0
SX2_k127_881352_4 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000001104 130.0
SX2_k127_881352_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000783 111.0
SX2_k127_881352_6 Preprotein translocase K03210 - - 0.000000000000003136 81.0
SX2_k127_892823_0 Ribosomal protein S1 K02945 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 555.0
SX2_k127_892823_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 411.0
SX2_k127_892823_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000002917 133.0
SX2_k127_892823_3 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000002684 130.0
SX2_k127_896242_0 amidohydrolase K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 381.0
SX2_k127_896242_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 311.0
SX2_k127_896242_2 transmembrane transport K02035,K15580 - - 0.0000000000000000002709 92.0
SX2_k127_930626_0 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000003912 258.0
SX2_k127_930626_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000004279 153.0
SX2_k127_930626_2 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000006898 124.0
SX2_k127_930626_3 PFAM ABC transporter related K01990 - - 0.0000000000000001942 83.0
SX2_k127_948384_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 597.0
SX2_k127_948384_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 468.0
SX2_k127_948384_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000002725 266.0
SX2_k127_948384_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000001189 198.0
SX2_k127_948384_4 Sua5 YciO YrdC YwlC family K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000002472 187.0
SX2_k127_948384_5 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000003974 176.0
SX2_k127_948384_6 Protein of unknown function (DUF1385) - - - 0.00000000001161 66.0
SX2_k127_963752_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001972 250.0
SX2_k127_963752_1 ATPases associated with a variety of cellular activities K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000008717 227.0
SX2_k127_963752_2 GYD domain - - - 0.0000000000000000000000000000005625 126.0
SX2_k127_963752_3 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000007631 118.0
SX2_k127_963752_4 FtsX-like permease family K02004 - - 0.0000000000000000000000001796 116.0
SX2_k127_963752_5 Transcriptional regulator - - - 0.000000000000000000000001387 111.0