Overview

ID MAG03646
Name SX2_bin.35
Sample SMP0092
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class GWC2-55-46
Order GWC2-55-46
Family DRQE01
Genus JAOUFM01
Species
Assembly information
Completeness (%) 88.0
Contamination (%) 2.24
GC content (%) 50.0
N50 (bp) 7,956
Genome size (bp) 1,541,997

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1552

Gene name Description KEGG GOs EC E-value Score Sequence
SX2_k127_1015696_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 472.0
SX2_k127_1015696_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000004983 224.0
SX2_k127_1015696_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000121 192.0
SX2_k127_1015696_3 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000003134 186.0
SX2_k127_1015696_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000002758 146.0
SX2_k127_1073889_0 Transport of potassium into the cell K03549 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 520.0
SX2_k127_1073889_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 436.0
SX2_k127_1073889_2 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 348.0
SX2_k127_1073889_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004194 263.0
SX2_k127_1073889_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000004729 238.0
SX2_k127_116523_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 580.0
SX2_k127_116523_1 Pfam:Arch_ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000259 273.0
SX2_k127_116523_2 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000000000000000000000000000002977 215.0
SX2_k127_116523_3 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000009659 162.0
SX2_k127_116523_4 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000001264 149.0
SX2_k127_116523_5 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000357 143.0
SX2_k127_116523_6 PFAM CheW domain protein K03408 - - 0.000000000000000000000005791 112.0
SX2_k127_1190916_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1059.0
SX2_k127_1190916_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.547e-253 812.0
SX2_k127_1190916_2 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000003301 210.0
SX2_k127_1190916_3 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000572 209.0
SX2_k127_1190916_4 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000004599 196.0
SX2_k127_1190916_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000001678 145.0
SX2_k127_1190916_6 Tetratricopeptide repeat - - - 0.000000000000000000000006211 108.0
SX2_k127_1190916_7 Glutathione peroxidase - - - 0.000009275 52.0
SX2_k127_1190916_8 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.000307 45.0
SX2_k127_1204272_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 398.0
SX2_k127_1204272_1 phosphoenolpyruvate-protein phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001186 220.0
SX2_k127_1204272_10 ResB-like family - - - 0.00006764 51.0
SX2_k127_1204272_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000151 217.0
SX2_k127_1204272_3 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000003099 209.0
SX2_k127_1204272_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000001044 129.0
SX2_k127_1204272_5 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate family K00171 - 1.2.7.1 0.00000000000000000000000000003214 119.0
SX2_k127_1204272_6 Helix-turn-helix domain - - - 0.000000000003712 77.0
SX2_k127_1204272_7 Tetratricopeptide TPR_2 - - - 0.0000000002948 64.0
SX2_k127_1214367_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 6.128e-231 727.0
SX2_k127_1214367_1 Peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 347.0
SX2_k127_1214367_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000003482 179.0
SX2_k127_1214367_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000001576 182.0
SX2_k127_1217151_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 492.0
SX2_k127_1217151_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 445.0
SX2_k127_1217151_10 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000002661 135.0
SX2_k127_1217151_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 437.0
SX2_k127_1217151_3 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 309.0
SX2_k127_1217151_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000001017 223.0
SX2_k127_1217151_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000343 215.0
SX2_k127_1217151_6 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000000000000000000002802 216.0
SX2_k127_1217151_7 Histidine kinase K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000005381 175.0
SX2_k127_1217151_8 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.0000000000000000000000000000000000002476 143.0
SX2_k127_1217151_9 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000001438 141.0
SX2_k127_1218508_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 518.0
SX2_k127_1218508_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 499.0
SX2_k127_1218508_2 Aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 428.0
SX2_k127_1218508_3 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000008876 242.0
SX2_k127_1218508_4 Rubrerythrin - - - 0.00000000000000001191 89.0
SX2_k127_1218508_5 - - - - 0.000000000000002292 79.0
SX2_k127_1254449_0 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 321.0
SX2_k127_1254449_1 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000001042 223.0
SX2_k127_1254449_2 Phosphomethylpyrimidine kinase K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000003059 180.0
SX2_k127_1254449_3 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000002138 66.0
SX2_k127_125809_0 Cytochrome C and Quinol oxidase polypeptide I K04561 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 568.0
SX2_k127_125809_1 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 323.0
SX2_k127_125809_2 Cytochrome c K02305 - - 0.0000000000000000000000000000000000000001795 154.0
SX2_k127_125809_3 - - - - 0.0000000000000000000002062 103.0
SX2_k127_1267923_0 PFAM Bacterial extracellular solute-binding - - - 3.725e-239 761.0
SX2_k127_1267923_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000001823 162.0
SX2_k127_128440_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 440.0
SX2_k127_128440_1 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000002927 235.0
SX2_k127_1284840_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 573.0
SX2_k127_1284840_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 297.0
SX2_k127_1284840_2 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 292.0
SX2_k127_1284840_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000003181 242.0
SX2_k127_1284840_4 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000007917 186.0
SX2_k127_1284840_5 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000003678 111.0
SX2_k127_1284840_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000002949 107.0
SX2_k127_1285927_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.672e-256 805.0
SX2_k127_1285927_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 365.0
SX2_k127_1285927_10 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0016485,GO:0016540,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564 4.1.1.11 0.0000000000000000000000000000000000000002064 153.0
SX2_k127_1285927_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 312.0
SX2_k127_1285927_3 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 311.0
SX2_k127_1285927_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006499 260.0
SX2_k127_1285927_5 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007394 254.0
SX2_k127_1285927_6 TIGRFAM cysteine desulfurase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000002926 221.0
SX2_k127_1285927_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000504 221.0
SX2_k127_1285927_8 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000461 209.0
SX2_k127_1285927_9 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000001411 208.0
SX2_k127_1305587_0 Endoribonuclease that initiates mRNA decay K18682 - - 5.076e-195 621.0
SX2_k127_1305587_1 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 300.0
SX2_k127_1305587_2 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000001325 162.0
SX2_k127_1305587_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000817 149.0
SX2_k127_1305587_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.0000001641 56.0
SX2_k127_130744_0 SMART Elongator protein 3 MiaB NifB - - - 7.1e-248 792.0
SX2_k127_130744_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 5.494e-198 636.0
SX2_k127_130744_10 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000001772 204.0
SX2_k127_130744_11 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000002061 156.0
SX2_k127_130744_12 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.00000000000000000000000000000000000000002948 157.0
SX2_k127_130744_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000001614 127.0
SX2_k127_130744_14 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000003837 103.0
SX2_k127_130744_15 - - - - 0.00000000000000000005229 92.0
SX2_k127_130744_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000002038 76.0
SX2_k127_130744_17 Prokaryotic N-terminal methylation motif - - - 0.0000000000009715 73.0
SX2_k127_130744_18 YHS domain - - - 0.0000000002685 64.0
SX2_k127_130744_2 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 521.0
SX2_k127_130744_3 Type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 493.0
SX2_k127_130744_4 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 491.0
SX2_k127_130744_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 473.0
SX2_k127_130744_6 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 336.0
SX2_k127_130744_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 296.0
SX2_k127_130744_8 Ankyrin repeats (many copies) K10380,K15502,K15503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008126 277.0
SX2_k127_130744_9 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000002266 232.0
SX2_k127_1321884_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 6.875e-299 942.0
SX2_k127_1321884_1 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 407.0
SX2_k127_1321884_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 385.0
SX2_k127_1321884_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000003082 223.0
SX2_k127_1387835_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 619.0
SX2_k127_1387835_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 610.0
SX2_k127_1387835_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 575.0
SX2_k127_1387835_3 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 556.0
SX2_k127_1387835_4 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 515.0
SX2_k127_1387835_5 protein histidine kinase activity K02482,K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 383.0
SX2_k127_1387835_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000002753 214.0
SX2_k127_1387835_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000007067 132.0
SX2_k127_1387835_8 B12 binding domain - - - 0.0000000000000000000000007518 105.0
SX2_k127_1387835_9 phosphorelay signal transduction system - - - 0.0001969 49.0
SX2_k127_1407859_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009892 265.0
SX2_k127_1407859_1 Glycosyltransferase Family 4 K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000004415 249.0
SX2_k127_1407859_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009567 242.0
SX2_k127_1407859_3 radical SAM domain protein K06139 - - 0.00000000000000000000000000000000000000000000000000000000000002456 227.0
SX2_k127_1407859_4 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000005435 199.0
SX2_k127_1407859_5 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000895 178.0
SX2_k127_1407859_6 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000001018 106.0
SX2_k127_1407859_7 Glycosyltransferase like family 2 K12988 - - 0.000000000000000162 81.0
SX2_k127_1407859_8 Methyltransferase domain - - - 0.0000000000000463 80.0
SX2_k127_1432390_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 614.0
SX2_k127_1432390_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 497.0
SX2_k127_1432390_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000004398 234.0
SX2_k127_1432390_11 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000003096 207.0
SX2_k127_1432390_12 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000002635 203.0
SX2_k127_1432390_13 AIR carboxylase K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000002395 193.0
SX2_k127_1432390_14 SmpB protein K03664 - - 0.00000000000000000000000000000000000000000000002748 174.0
SX2_k127_1432390_15 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000001959 166.0
SX2_k127_1432390_16 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000000000005272 121.0
SX2_k127_1432390_17 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000003271 113.0
SX2_k127_1432390_18 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000008212 109.0
SX2_k127_1432390_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000004728 92.0
SX2_k127_1432390_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 479.0
SX2_k127_1432390_20 - K07275 - - 0.000000000000001637 85.0
SX2_k127_1432390_21 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000001412 73.0
SX2_k127_1432390_22 response to oxidative stress K03803 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000004303 69.0
SX2_k127_1432390_3 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 381.0
SX2_k127_1432390_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 342.0
SX2_k127_1432390_5 PFAM ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 319.0
SX2_k127_1432390_6 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 319.0
SX2_k127_1432390_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 319.0
SX2_k127_1432390_8 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003829 265.0
SX2_k127_1432390_9 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004047 261.0
SX2_k127_14454_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.125e-215 681.0
SX2_k127_14454_1 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 324.0
SX2_k127_14454_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 293.0
SX2_k127_14454_3 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 GO:0003674,GO:0003824,GO:0004850,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006218,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016043,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0022607,GO:0030955,GO:0031420,GO:0033554,GO:0034214,GO:0034641,GO:0034655,GO:0034656,GO:0042454,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046108,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0050896,GO:0051259,GO:0051716,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.3 0.000000000000000007957 85.0
SX2_k127_1501580_0 oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 444.0
SX2_k127_1501580_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 391.0
SX2_k127_1501580_2 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 367.0
SX2_k127_1501580_3 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000000000005394 174.0
SX2_k127_1501580_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000004043 136.0
SX2_k127_1504880_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 572.0
SX2_k127_1504880_1 PFAM methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000001597 199.0
SX2_k127_1504880_2 - - - - 0.00000000000000000000000000000000000000000000002721 175.0
SX2_k127_1510123_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000001757 118.0
SX2_k127_1524289_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.205e-268 844.0
SX2_k127_1524289_1 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 410.0
SX2_k127_1524289_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 291.0
SX2_k127_1524289_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000002044 122.0
SX2_k127_1524289_4 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000001316 78.0
SX2_k127_1524289_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000002088 75.0
SX2_k127_1545353_0 (Rhomboid) family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000001725 224.0
SX2_k127_1545353_1 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000009032 153.0
SX2_k127_1566393_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 604.0
SX2_k127_1566393_1 phosphoprotein phosphatase activity - - - 0.0000000000000000000000003258 108.0
SX2_k127_1568718_0 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002369 287.0
SX2_k127_1568718_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000001532 222.0
SX2_k127_1568718_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000006771 211.0
SX2_k127_1568718_3 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.00000000000000000000000000000002739 132.0
SX2_k127_1573612_0 Molybdopterin K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 462.0
SX2_k127_1573612_1 May be involved in the biosynthesis of molybdopterin K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000003033 242.0
SX2_k127_1573612_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000001259 110.0
SX2_k127_1573612_3 Uncharacterized conserved protein (DUF2299) - - - 0.00000006571 61.0
SX2_k127_1593187_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 457.0
SX2_k127_1593187_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000000004852 139.0
SX2_k127_1593187_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000003548 104.0
SX2_k127_1626495_0 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 567.0
SX2_k127_1626495_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 527.0
SX2_k127_1626495_10 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000004326 165.0
SX2_k127_1626495_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000006313 98.0
SX2_k127_1626495_12 Polymer-forming cytoskeletal - - - 0.000000000000000009795 89.0
SX2_k127_1626495_13 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000000000005706 81.0
SX2_k127_1626495_14 PFAM FecR protein - - - 0.000000002502 68.0
SX2_k127_1626495_15 FecR protein - - - 0.0000001109 62.0
SX2_k127_1626495_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 449.0
SX2_k127_1626495_3 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 417.0
SX2_k127_1626495_4 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 325.0
SX2_k127_1626495_5 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003571 261.0
SX2_k127_1626495_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000006392 210.0
SX2_k127_1626495_7 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000006816 185.0
SX2_k127_1626495_8 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000003685 196.0
SX2_k127_1626495_9 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000002385 166.0
SX2_k127_1643626_0 long-chain fatty acid transport protein - - - 0.0 1086.0
SX2_k127_1643626_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 533.0
SX2_k127_1643626_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 488.0
SX2_k127_1643626_3 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000494 151.0
SX2_k127_1643626_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000007513 113.0
SX2_k127_1643626_5 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000004065 83.0
SX2_k127_1653967_0 Heat shock 70 kDa protein K04043 - - 3.386e-263 825.0
SX2_k127_1653967_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 474.0
SX2_k127_1653967_2 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 474.0
SX2_k127_1653967_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001985 238.0
SX2_k127_1653967_4 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000004509 154.0
SX2_k127_1653967_5 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000002962 110.0
SX2_k127_1653967_6 Tetratricopeptide repeat - - - 0.000000005708 68.0
SX2_k127_1668170_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 407.0
SX2_k127_1668170_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000001395 211.0
SX2_k127_1668170_2 Peptidase U32 - - - 0.00000000000000000000000000000000000004365 152.0
SX2_k127_1672683_0 GTP1/OBG K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003643 279.0
SX2_k127_1672683_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000006053 246.0
SX2_k127_169519_0 threonyl-tRNA aminoacylation K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 565.0
SX2_k127_169519_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000007496 193.0
SX2_k127_169519_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000001048 136.0
SX2_k127_169519_3 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000007203 71.0
SX2_k127_169519_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00001868 49.0
SX2_k127_1701327_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 647.0
SX2_k127_1701327_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 440.0
SX2_k127_1701327_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 383.0
SX2_k127_1701327_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002152 282.0
SX2_k127_1701327_4 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000003894 263.0
SX2_k127_1701327_5 DNA packaging - - - 0.0000000000000000000000000000000000000000000000000000000000001184 229.0
SX2_k127_1701327_6 - - - - 0.00000008175 63.0
SX2_k127_1701327_7 Protein of unknown function (DUF3108) - - - 0.00009911 53.0
SX2_k127_173348_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 444.0
SX2_k127_173348_1 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000001581 111.0
SX2_k127_173348_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000003347 113.0
SX2_k127_173348_3 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000002566 67.0
SX2_k127_173348_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.000003138 50.0
SX2_k127_1784705_0 response to heat K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 518.0
SX2_k127_1784705_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007263 293.0
SX2_k127_1784705_2 SMART Heat shock protein DnaJ K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004055 265.0
SX2_k127_1787089_0 Methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000004313 239.0
SX2_k127_1787089_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000001221 238.0
SX2_k127_1787089_2 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000001292 143.0
SX2_k127_1803708_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 527.0
SX2_k127_1803708_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 438.0
SX2_k127_1803708_10 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000003095 175.0
SX2_k127_1803708_11 PFAM transcription factor CarD K07736 - - 0.0000000000000000000000000000000000000000000004908 170.0
SX2_k127_1803708_12 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000001411 147.0
SX2_k127_1803708_13 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04068 - 1.97.1.4 0.000000000000000000000000000000002341 136.0
SX2_k127_1803708_14 heat shock protein 70 - - - 0.000000000000000000000000005068 129.0
SX2_k127_1803708_15 PilZ domain - - - 0.00000000000000000001689 95.0
SX2_k127_1803708_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 378.0
SX2_k127_1803708_3 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 375.0
SX2_k127_1803708_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 344.0
SX2_k127_1803708_5 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005079 261.0
SX2_k127_1803708_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000008357 211.0
SX2_k127_1803708_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000002063 198.0
SX2_k127_1803708_8 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000000000000000000000006052 185.0
SX2_k127_1803708_9 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000003746 182.0
SX2_k127_1826019_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 589.0
SX2_k127_1826019_1 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 389.0
SX2_k127_1826019_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 385.0
SX2_k127_1826019_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 345.0
SX2_k127_1826019_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 298.0
SX2_k127_1826019_5 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000021 289.0
SX2_k127_1826019_6 Glutamine amidotransferase of anthranilate synthase K01664 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000001111 241.0
SX2_k127_1826019_7 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000001865 244.0
SX2_k127_1826019_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000003181 217.0
SX2_k127_1826019_9 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000001111 222.0
SX2_k127_1828586_0 Polyphosphate kinase 2 (PPK2) - - - 4.76e-213 672.0
SX2_k127_1828586_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.628e-206 665.0
SX2_k127_1828586_2 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000008222 198.0
SX2_k127_1828586_3 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000008337 132.0
SX2_k127_1828586_4 PFAM CHAD domain containing protein - - - 0.0000000000000000008073 98.0
SX2_k127_183324_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 426.0
SX2_k127_183324_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000009566 186.0
SX2_k127_1834272_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 409.0
SX2_k127_1834272_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000005967 202.0
SX2_k127_1834272_2 energy transducer activity K03646,K03832 - - 0.0000000003156 68.0
SX2_k127_1835965_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 7.308e-253 790.0
SX2_k127_1835965_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.761e-250 781.0
SX2_k127_1835965_10 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000005251 154.0
SX2_k127_1835965_11 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000003563 150.0
SX2_k127_1835965_12 Protein of unknown function (DUF465) K09794 - - 0.0000003267 55.0
SX2_k127_1835965_13 Tetratricopeptide repeat - - - 0.0000405 53.0
SX2_k127_1835965_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 506.0
SX2_k127_1835965_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 389.0
SX2_k127_1835965_4 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 353.0
SX2_k127_1835965_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 286.0
SX2_k127_1835965_6 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000001412 223.0
SX2_k127_1835965_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000007498 214.0
SX2_k127_1835965_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000004215 214.0
SX2_k127_1835965_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000001915 206.0
SX2_k127_1839320_0 Sporulation initiation inhibitor protein Soj K03496 - - 0.0000000000000000000000000000000000000000000000000000000002552 211.0
SX2_k127_1839320_1 histidine kinase - - - 0.00000000000000000000000000000418 132.0
SX2_k127_1839320_2 HD domain - - - 0.0000000000000000000008239 107.0
SX2_k127_1839320_3 Two component signalling adaptor domain K03408 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.000004126 54.0
SX2_k127_1845182_0 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 330.0
SX2_k127_1845182_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 325.0
SX2_k127_1845182_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 276.0
SX2_k127_1845182_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000004326 169.0
SX2_k127_1883556_0 Large extracellular alpha-helical protein K06894 - - 0.0 1375.0
SX2_k127_191730_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 398.0
SX2_k127_191730_1 quinolinate catabolic process K00278,K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 303.0
SX2_k127_191730_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009302 274.0
SX2_k127_191730_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000004976 74.0
SX2_k127_1942816_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 297.0
SX2_k127_1942816_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000009966 214.0
SX2_k127_1942816_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.000000000000000000000000000000000000000000000004069 173.0
SX2_k127_1942816_3 Domain of unknown function (DUF374) K02527,K09778 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000009775 164.0
SX2_k127_1942816_4 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.000000000000002088 76.0
SX2_k127_196897_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.641e-196 625.0
SX2_k127_196897_1 nitrite transmembrane transporter activity K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 529.0
SX2_k127_196897_10 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002283 272.0
SX2_k127_196897_11 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000002704 253.0
SX2_k127_196897_12 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004987 248.0
SX2_k127_196897_13 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000003583 236.0
SX2_k127_196897_14 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000511 238.0
SX2_k127_196897_15 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000001851 223.0
SX2_k127_196897_16 alpha beta - - - 0.000000000000000000000000000000000000000000000000000004871 199.0
SX2_k127_196897_17 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000006852 188.0
SX2_k127_196897_18 PFAM Lytic K08309 - - 0.00000000000000000000000000000000000000000000004021 176.0
SX2_k127_196897_19 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000001387 179.0
SX2_k127_196897_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 531.0
SX2_k127_196897_20 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000000309 169.0
SX2_k127_196897_21 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000001481 167.0
SX2_k127_196897_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000002504 153.0
SX2_k127_196897_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.000000000000000000000000000000000004588 152.0
SX2_k127_196897_24 Endonuclease containing a URI domain K07461 - - 0.00000000000000000000000000000000006974 136.0
SX2_k127_196897_25 cheY-homologous receiver domain K03413 - - 0.000000000116 72.0
SX2_k127_196897_26 PFAM ATP-binding region ATPase domain protein - - - 0.0000000264 64.0
SX2_k127_196897_28 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000179 51.0
SX2_k127_196897_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 477.0
SX2_k127_196897_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 327.0
SX2_k127_196897_5 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 320.0
SX2_k127_196897_6 Alcohol dehydrogenase GroES domain protein K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 318.0
SX2_k127_196897_7 Anthranilate synthase component I, N terminal region K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 310.0
SX2_k127_196897_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 285.0
SX2_k127_196897_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009898 280.0
SX2_k127_2030212_0 PFAM AsmA family protein K07290 - - 0.0000000000000000000000000000000000000000000000000000000000002818 231.0
SX2_k127_2032756_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002258 253.0
SX2_k127_2032756_1 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000003238 221.0
SX2_k127_2032756_2 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000008257 144.0
SX2_k127_2056674_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 334.0
SX2_k127_209148_0 EamA-like transporter family - - - 0.0000000000000000000000000000001998 134.0
SX2_k127_209148_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000569 121.0
SX2_k127_2106178_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 538.0
SX2_k127_2106178_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 284.0
SX2_k127_2106178_2 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 0.00000000000000000000000000000000000000000000000000001045 192.0
SX2_k127_2127567_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.443e-197 634.0
SX2_k127_2127567_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 320.0
SX2_k127_2127567_2 Mediates zinc uptake. May also transport other divalent cations K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000001083 233.0
SX2_k127_2170238_0 Selenide, water dikinase K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 321.0
SX2_k127_2170238_1 auxin efflux carrier family protein K07088 - - 0.00000000000000008033 84.0
SX2_k127_2170238_2 elongation factor SelB, winged helix K03833 - - 0.000000000006056 74.0
SX2_k127_2170238_3 Multidrug MFS transporter - - - 0.00000001294 64.0
SX2_k127_2172617_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.594e-266 846.0
SX2_k127_2172617_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 370.0
SX2_k127_2172617_2 Bacterial type II and III secretion system protein - - - 0.00000000005776 72.0
SX2_k127_22100_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.83e-227 715.0
SX2_k127_22100_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 9.267e-195 616.0
SX2_k127_22100_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 464.0
SX2_k127_22100_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007422 283.0
SX2_k127_22100_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000004384 244.0
SX2_k127_22100_5 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000005845 199.0
SX2_k127_22100_6 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000212 113.0
SX2_k127_22100_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000001875 70.0
SX2_k127_22100_8 Transcription factor Pur-alpha K21772 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0044424,GO:0044464,GO:0046686,GO:0050896,GO:0097159,GO:1901363 - 0.0000001454 56.0
SX2_k127_2278030_0 Aminotransferase, class I K14261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 601.0
SX2_k127_2278030_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 499.0
SX2_k127_2278030_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000852 261.0
SX2_k127_2278030_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000002191 253.0
SX2_k127_2280948_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1036.0
SX2_k127_2280948_1 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 616.0
SX2_k127_2280948_2 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000002403 55.0
SX2_k127_2280948_3 Outer membrane lipoprotein K05807 - - 0.0001078 53.0
SX2_k127_2280948_4 PilZ domain - - - 0.0001157 47.0
SX2_k127_2300689_0 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 1.096e-210 662.0
SX2_k127_2300689_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000001073 178.0
SX2_k127_2311116_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239,K18556 - 1.3.1.6,1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 366.0
SX2_k127_2311116_1 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000002961 165.0
SX2_k127_2311116_2 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.0000000000000000000000000000000000007308 142.0
SX2_k127_2311892_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 514.0
SX2_k127_2311892_1 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 470.0
SX2_k127_2311892_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 307.0
SX2_k127_2319269_0 histidine kinase, HAMP K13598 - 2.7.13.3 2.784e-196 632.0
SX2_k127_2319269_1 response regulator K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 546.0
SX2_k127_2319269_10 dnak suppressor protein K06204 - - 0.00000000000000000000001696 105.0
SX2_k127_2319269_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 460.0
SX2_k127_2319269_3 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 415.0
SX2_k127_2319269_4 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 428.0
SX2_k127_2319269_5 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 356.0
SX2_k127_2319269_6 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 296.0
SX2_k127_2319269_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000001515 194.0
SX2_k127_2319269_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000002606 185.0
SX2_k127_2319269_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000008119 153.0
SX2_k127_2320285_0 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 402.0
SX2_k127_2320285_1 Semialdehyde dehydrogenase, NAD binding domain K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 392.0
SX2_k127_2320285_10 Pfam Methyltransferase - - - 0.00000000000000002137 87.0
SX2_k127_2320285_11 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000002803 71.0
SX2_k127_2320285_2 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000002843 227.0
SX2_k127_2320285_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000008476 205.0
SX2_k127_2320285_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001186 186.0
SX2_k127_2320285_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000003594 166.0
SX2_k127_2320285_7 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000004299 104.0
SX2_k127_2320285_8 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000002508 100.0
SX2_k127_2320285_9 - - - - 0.000000000000000000002078 95.0
SX2_k127_2369155_0 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 289.0
SX2_k127_2369155_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03522,K05337 - - 0.0000000000000000002666 90.0
SX2_k127_2369155_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000005235 86.0
SX2_k127_2369155_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000002375 54.0
SX2_k127_2369155_4 AsmA family K07290 - - 0.0003431 49.0
SX2_k127_2372638_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 5.265e-231 740.0
SX2_k127_2372638_1 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 587.0
SX2_k127_2372638_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000004908 237.0
SX2_k127_2372638_11 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000001242 183.0
SX2_k127_2372638_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000001414 176.0
SX2_k127_2372638_13 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000123 163.0
SX2_k127_2372638_14 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000000007778 143.0
SX2_k127_2372638_15 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000002749 141.0
SX2_k127_2372638_16 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000003057 140.0
SX2_k127_2372638_17 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000002917 119.0
SX2_k127_2372638_18 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000003484 117.0
SX2_k127_2372638_19 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000009795 94.0
SX2_k127_2372638_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 464.0
SX2_k127_2372638_20 Roadblock/LC7 domain - - - 0.000000000000000000095 93.0
SX2_k127_2372638_21 Pilus assembly protein, PilP K02665 - - 0.000000000329 68.0
SX2_k127_2372638_22 Protein of unknown function (DUF448) K07742 - - 0.000007611 51.0
SX2_k127_2372638_3 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 422.0
SX2_k127_2372638_4 PFAM type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 421.0
SX2_k127_2372638_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 357.0
SX2_k127_2372638_6 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 309.0
SX2_k127_2372638_7 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 293.0
SX2_k127_2372638_8 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007265 278.0
SX2_k127_2372638_9 tRNA pseudouridylate synthase B C-terminal domain K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000671 240.0
SX2_k127_2376644_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 604.0
SX2_k127_2376644_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 318.0
SX2_k127_2376644_2 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 316.0
SX2_k127_2376644_3 PFAM SAICAR synthetase K01756,K01923 - 4.3.2.2,6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 308.0
SX2_k127_2376644_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000009 108.0
SX2_k127_2376644_5 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000000000000009012 114.0
SX2_k127_2376644_7 CI repressor - - - 0.00000000338 64.0
SX2_k127_2376644_8 - - - - 0.000002998 49.0
SX2_k127_2376644_9 Transcriptional - - - 0.000008349 55.0
SX2_k127_2382269_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 383.0
SX2_k127_2382269_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000456 228.0
SX2_k127_2382269_2 hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000002552 181.0
SX2_k127_2382269_3 Putative RNA methylase family UPF0020 K15460 - 2.1.1.223 0.00000000000000000000005907 106.0
SX2_k127_2382269_4 haemagglutination activity domain - - - 0.00000000000000000000288 97.0
SX2_k127_2382269_5 - - - - 0.0000000000000006732 80.0
SX2_k127_2382269_6 Protein of unknown function (DUF721) - - - 0.0000001407 60.0
SX2_k127_2399639_0 sulfate adenylyltransferase K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 503.0
SX2_k127_2399639_1 Catalyzes the synthesis of activated sulfate K00860 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016740,GO:0016772,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 344.0
SX2_k127_2399639_2 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000001387 230.0
SX2_k127_2399639_3 AMP binding K03499,K06149 - - 0.000008774 50.0
SX2_k127_24104_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 587.0
SX2_k127_24104_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 364.0
SX2_k127_24104_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000178 80.0
SX2_k127_2427800_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 506.0
SX2_k127_2427800_1 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000004059 122.0
SX2_k127_2427800_2 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.00000000000000000000000003893 111.0
SX2_k127_2427800_3 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000006159 62.0
SX2_k127_2449144_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 2.885e-262 830.0
SX2_k127_2449144_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 347.0
SX2_k127_2449144_2 TRAM domain K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000001466 272.0
SX2_k127_2449144_3 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000003782 218.0
SX2_k127_2449144_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000004619 145.0
SX2_k127_2449144_5 - - - - 0.000000000000000000000000003242 125.0
SX2_k127_2449144_6 Tetratricopeptide repeat - - - 0.00000000000000002036 94.0
SX2_k127_2449144_7 tetratricopeptide repeat - - - 0.0000000000003664 79.0
SX2_k127_2449144_8 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000001208 64.0
SX2_k127_2469419_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 326.0
SX2_k127_2469419_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000000001268 143.0
SX2_k127_2469419_2 - - - - 0.0000000000000000000000000001575 124.0
SX2_k127_2469419_3 peptidyl-tyrosine sulfation - - - 0.0001038 51.0
SX2_k127_24840_0 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 572.0
SX2_k127_24840_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 325.0
SX2_k127_24840_2 Succinyl-CoA ligase like flavodoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007168 224.0
SX2_k127_24840_3 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000001012 119.0
SX2_k127_24840_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000002978 81.0
SX2_k127_2593647_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003416 273.0
SX2_k127_2593647_1 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000007081 254.0
SX2_k127_2593647_2 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000000000000000000000000000000005111 233.0
SX2_k127_2593647_3 Glycosyl hydrolases family 15 K07190 - - 0.000000000000000000000000000000000000000000000000000000001262 216.0
SX2_k127_2593647_4 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000001067 174.0
SX2_k127_2645139_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.175e-201 651.0
SX2_k127_2645139_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000003638 137.0
SX2_k127_2645139_2 Cytochrome c - - - 0.00000000000000000000000002924 115.0
SX2_k127_2658482_0 chelatase, subunit ChlI K07391 - - 1.694e-198 631.0
SX2_k127_2658482_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 343.0
SX2_k127_2658482_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 345.0
SX2_k127_2658482_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 305.0
SX2_k127_2658482_4 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000008644 196.0
SX2_k127_2658482_5 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000003216 159.0
SX2_k127_2666200_0 transport - - - 0.0000000000000000000000000000000593 134.0
SX2_k127_2666200_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000008115 94.0
SX2_k127_2666200_2 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.0002478 46.0
SX2_k127_2672043_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 2.754e-199 636.0
SX2_k127_2672043_1 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 564.0
SX2_k127_2672043_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000495 126.0
SX2_k127_2672043_11 - - - - 0.0000000000002844 74.0
SX2_k127_2672043_2 Oxidoreductase K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 571.0
SX2_k127_2672043_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 437.0
SX2_k127_2672043_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 395.0
SX2_k127_2672043_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000006238 220.0
SX2_k127_2672043_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000001858 163.0
SX2_k127_2672043_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000398 154.0
SX2_k127_2672043_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000002591 153.0
SX2_k127_2672043_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000003556 139.0
SX2_k127_2677915_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003771 275.0
SX2_k127_2677915_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000002652 173.0
SX2_k127_2677915_2 Protein of unknown function (DUF2914) - - - 0.00002848 47.0
SX2_k127_274344_0 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000001313 153.0
SX2_k127_274344_1 RelE-like toxin of type II toxin-antitoxin system HigB K07334 GO:0008150,GO:0008219,GO:0009987 - 0.00000000000000000000000000006888 117.0
SX2_k127_274344_2 addiction module antidote protein HigA K21498 - - 0.000000000000000000000000002969 114.0
SX2_k127_274344_3 - - - - 0.000000000000004291 76.0
SX2_k127_2761865_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 414.0
SX2_k127_2761865_1 DNA helicase K03657 - 3.6.4.12 0.000000000000000004762 87.0
SX2_k127_2768026_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.046e-271 843.0
SX2_k127_2768026_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005264 243.0
SX2_k127_2768026_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000002166 149.0
SX2_k127_277340_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 304.0
SX2_k127_277340_1 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000005017 241.0
SX2_k127_277340_2 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168 - 0.0000000000000000000000000000000000000000000000003142 185.0
SX2_k127_277340_3 heat shock protein binding K05516,K05801 - - 0.00000000000000000005138 101.0
SX2_k127_277340_4 molybdate ion transport K02019 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000006346 79.0
SX2_k127_2774552_0 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 335.0
SX2_k127_2774552_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 289.0
SX2_k127_2774552_2 protein conserved in bacteria K09798 - - 0.0000000000000000000000000000001199 127.0
SX2_k127_2774552_3 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000003165 117.0
SX2_k127_277762_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 418.0
SX2_k127_277762_1 Roadblock/LC7 domain - - - 0.0000000000000000000213 94.0
SX2_k127_280080_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 437.0
SX2_k127_280080_1 Tetratricopeptide TPR_2 repeat protein K12600 - - 0.0000000000000000000000000000000000003623 151.0
SX2_k127_280080_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000001192 123.0
SX2_k127_280080_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000006092 72.0
SX2_k127_280080_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000006733 67.0
SX2_k127_2803024_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.516e-196 627.0
SX2_k127_2803024_1 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.00000000000000000000000000000000000000004682 154.0
SX2_k127_2803024_2 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000004777 85.0
SX2_k127_2809491_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000167 272.0
SX2_k127_2809491_1 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000001457 123.0
SX2_k127_2809491_2 Rubrerythrin - - - 0.0000000001217 63.0
SX2_k127_2809491_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0001627 48.0
SX2_k127_2885922_0 conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000001026 205.0
SX2_k127_2885922_1 Protein of unknown function (DUF3015) - - - 0.0000000000000000000000000000000001285 138.0
SX2_k127_2885922_2 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000001576 117.0
SX2_k127_2895407_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 3.604e-202 646.0
SX2_k127_2895407_1 Bacterial cellulose synthase subunit K20541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 509.0
SX2_k127_2895407_2 modulates the activities of several proteins which are inactive in their K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 335.0
SX2_k127_2895407_3 PFAM Glycosyl hydrolases family 8 K20542 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000001279 239.0
SX2_k127_2895407_4 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000357 233.0
SX2_k127_2895407_5 peptidyl-tyrosine sulfation K20543 - - 0.00000000000000000000000000000000000000000001109 183.0
SX2_k127_2895407_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000001317 169.0
SX2_k127_2895407_7 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000637 124.0
SX2_k127_2895407_8 Glycosyl transferase family 21 K00694 - 2.4.1.12 0.00000000000000001312 88.0
SX2_k127_2898420_0 4Fe-4S dicluster domain K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 5.008e-197 626.0
SX2_k127_2898420_1 Transporter K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 486.0
SX2_k127_2898420_2 Molybdopterin oxidoreductase K00370,K17050 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000005892 235.0
SX2_k127_2898420_3 Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000007702 211.0
SX2_k127_2898420_4 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000004793 93.0
SX2_k127_2898420_5 Nitrate reductase K00373 - - 0.00000007287 61.0
SX2_k127_2898420_6 Protein of unknown function (DUF2769) - - - 0.00004465 50.0
SX2_k127_2940233_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 400.0
SX2_k127_2940233_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000001441 108.0
SX2_k127_2940233_2 - - - - 0.0000000000000009582 79.0
SX2_k127_294771_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 597.0
SX2_k127_294771_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 579.0
SX2_k127_294771_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000003616 190.0
SX2_k127_294771_11 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000009941 161.0
SX2_k127_294771_12 calmodulin binding K19626 GO:0001655,GO:0001736,GO:0001738,GO:0001822,GO:0001947,GO:0002009,GO:0003002,GO:0003007,GO:0003143,GO:0003341,GO:0003351,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005819,GO:0005856,GO:0005929,GO:0006810,GO:0006928,GO:0007017,GO:0007018,GO:0007164,GO:0007275,GO:0007368,GO:0007369,GO:0007389,GO:0007507,GO:0008104,GO:0008150,GO:0009653,GO:0009790,GO:0009791,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009966,GO:0009968,GO:0009987,GO:0010171,GO:0010646,GO:0010648,GO:0015031,GO:0015630,GO:0015833,GO:0016020,GO:0023051,GO:0023057,GO:0030111,GO:0030178,GO:0031016,GO:0032501,GO:0032502,GO:0033036,GO:0035050,GO:0035239,GO:0035295,GO:0035844,GO:0036372,GO:0042886,GO:0042995,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044422,GO:0044424,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0045184,GO:0048471,GO:0048513,GO:0048519,GO:0048523,GO:0048546,GO:0048562,GO:0048565,GO:0048568,GO:0048583,GO:0048585,GO:0048598,GO:0048645,GO:0048646,GO:0048729,GO:0048731,GO:0048793,GO:0048856,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0055123,GO:0060026,GO:0060027,GO:0060287,GO:0060429,GO:0060562,GO:0060828,GO:0060971,GO:0060972,GO:0060993,GO:0061371,GO:0065007,GO:0071702,GO:0071705,GO:0072001,GO:0072003,GO:0072114,GO:0072116,GO:0072359,GO:0090090,GO:0097543,GO:0097546,GO:0120025,GO:0120038 - 0.000000000000000000000000000000000000000001022 173.0
SX2_k127_294771_13 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000003034 151.0
SX2_k127_294771_14 regulation of translation K03530 - - 0.00000000000000000000000000000000003773 136.0
SX2_k127_294771_15 - - - - 0.0000000000000000000000000004355 122.0
SX2_k127_294771_16 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000003488 112.0
SX2_k127_294771_17 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000472 83.0
SX2_k127_294771_19 cytochrome c biogenesis protein K07399 - - 0.000737 48.0
SX2_k127_294771_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 445.0
SX2_k127_294771_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 434.0
SX2_k127_294771_4 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 370.0
SX2_k127_294771_5 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 358.0
SX2_k127_294771_6 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 322.0
SX2_k127_294771_7 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000002696 215.0
SX2_k127_294771_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000006524 206.0
SX2_k127_294771_9 Ankyrin repeat domain-containing protein 50-like K21440 - - 0.000000000000000000000000000000000000000000000000000004835 213.0
SX2_k127_2957674_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 460.0
SX2_k127_2957674_1 Bacterial regulatory protein, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 444.0
SX2_k127_2957674_10 Belongs to the sulfur carrier protein TusA family - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000003774 89.0
SX2_k127_2957674_11 SMART PDZ DHR GLGF domain protein - - - 0.00000000005532 68.0
SX2_k127_2957674_12 Rubrerythrin - - - 0.0000000008055 66.0
SX2_k127_2957674_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 412.0
SX2_k127_2957674_3 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 377.0
SX2_k127_2957674_4 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 323.0
SX2_k127_2957674_5 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001056 232.0
SX2_k127_2957674_6 COG2189 Adenine specific DNA methylase Mod K00571,K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000009595 212.0
SX2_k127_2957674_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000006556 176.0
SX2_k127_2957674_8 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000003513 163.0
SX2_k127_2957674_9 Ferredoxin - - - 0.000000000000000000000004041 105.0
SX2_k127_2969618_0 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 442.0
SX2_k127_2969618_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 326.0
SX2_k127_2969618_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000294 285.0
SX2_k127_2969618_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000002196 130.0
SX2_k127_2969618_4 PFAM UvrD REP helicase - - - 0.0000000000000000000004966 96.0
SX2_k127_2969618_5 TonB C terminal K03832 - - 0.000000000000000000099 99.0
SX2_k127_2969618_6 - - - - 0.000000000000000002455 94.0
SX2_k127_2969618_7 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000009479 88.0
SX2_k127_2969618_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000006979 68.0
SX2_k127_2969618_9 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000737 74.0
SX2_k127_2992587_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 329.0
SX2_k127_2992587_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 321.0
SX2_k127_3017521_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 612.0
SX2_k127_3017521_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 469.0
SX2_k127_3050554_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 493.0
SX2_k127_3050554_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 414.0
SX2_k127_3050554_10 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000116 182.0
SX2_k127_3050554_11 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000007332 158.0
SX2_k127_3050554_12 Belongs to the Fur family K09825 - - 0.00000000000000000000000000000000000000335 150.0
SX2_k127_3050554_13 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000004603 120.0
SX2_k127_3050554_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000003111 101.0
SX2_k127_3050554_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 344.0
SX2_k127_3050554_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 333.0
SX2_k127_3050554_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 329.0
SX2_k127_3050554_5 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 302.0
SX2_k127_3050554_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001577 268.0
SX2_k127_3050554_7 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000005304 221.0
SX2_k127_3050554_8 chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000001311 212.0
SX2_k127_3050554_9 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000000000001811 208.0
SX2_k127_3068900_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 462.0
SX2_k127_3068900_1 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 378.0
SX2_k127_3068900_10 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000001861 68.0
SX2_k127_3068900_11 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000006478 59.0
SX2_k127_3068900_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003994 272.0
SX2_k127_3068900_3 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001961 255.0
SX2_k127_3068900_4 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.00000000000000000000000000000000000000000000000002533 186.0
SX2_k127_3068900_5 Belongs to the Fur family K09825 - - 0.000000000000000000000000000000000000004873 149.0
SX2_k127_3068900_6 radical SAM domain protein - - - 0.000000000000000000000000000000007193 133.0
SX2_k127_3068900_7 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000009901 134.0
SX2_k127_3068900_8 PFAM Tetratricopeptide repeat - - - 0.0000000000000000002452 98.0
SX2_k127_3068900_9 - - - - 0.0000000000000003446 85.0
SX2_k127_3076073_0 Pfam:N_methyl_2 K02456 - - 0.0000000000000000000000000000000000000000000000002601 181.0
SX2_k127_3076073_1 Type II secretory pathway, pseudopilin - - - 0.0000000000000000000000000000000000001336 147.0
SX2_k127_3076073_2 Type II secretion system protein G K02456 - - 0.0000000000000000000000000000000002932 135.0
SX2_k127_3076073_3 TIGRFAM general secretion pathway protein F K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000106 90.0
SX2_k127_3076073_4 type II and III secretion system protein K02453 - - 0.0006473 47.0
SX2_k127_3078351_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 396.0
SX2_k127_3078351_1 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007599 272.0
SX2_k127_3107336_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 4.827e-194 628.0
SX2_k127_3107336_1 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 594.0
SX2_k127_3107336_2 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 535.0
SX2_k127_3107336_3 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 515.0
SX2_k127_3107336_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 305.0
SX2_k127_3107336_5 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 295.0
SX2_k127_3107336_6 Secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000000000000000000005914 166.0
SX2_k127_3107336_7 PFAM Sporulation and spore germination - - - 0.000000000000000000002683 101.0
SX2_k127_3128943_0 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 512.0
SX2_k127_3128943_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 358.0
SX2_k127_3128943_2 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 342.0
SX2_k127_3128943_3 cytochrome c oxidase, subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000000006512 163.0
SX2_k127_3128943_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000009296 157.0
SX2_k127_3128943_5 signal sequence binding K07152 - - 0.000000000000000000000000000000001819 138.0
SX2_k127_3128943_6 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000003201 133.0
SX2_k127_3128943_7 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000002636 128.0
SX2_k127_3128943_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000001858 91.0
SX2_k127_3128943_9 FtsZ-dependent cytokinesis - - - 0.000000000000002508 85.0
SX2_k127_3136174_0 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000001024 92.0
SX2_k127_3136174_1 C4-type zinc ribbon domain K07164 - - 0.0000000000000000007959 95.0
SX2_k127_3136174_2 - - - - 0.000000000000000002567 87.0
SX2_k127_3161284_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.943e-301 948.0
SX2_k127_3161284_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.899e-202 638.0
SX2_k127_3161284_10 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 299.0
SX2_k127_3161284_11 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004162 293.0
SX2_k127_3161284_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000001838 193.0
SX2_k127_3161284_13 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000003084 156.0
SX2_k127_3161284_14 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000006089 154.0
SX2_k127_3161284_15 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000009893 147.0
SX2_k127_3161284_16 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000009524 138.0
SX2_k127_3161284_17 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000009479 128.0
SX2_k127_3161284_18 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000001544 128.0
SX2_k127_3161284_19 PTS system fructose IIA component K02793 - 2.7.1.191 0.000000000000000000000000004455 115.0
SX2_k127_3161284_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 566.0
SX2_k127_3161284_20 PTS HPr component phosphorylation site K11189 - - 0.00000000000000000000000001092 111.0
SX2_k127_3161284_21 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.000000000000000002048 91.0
SX2_k127_3161284_22 regulation of DNA repair K03565 - - 0.0000001609 59.0
SX2_k127_3161284_23 shape-determining protein MreD K03571 - - 0.0006493 49.0
SX2_k127_3161284_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 563.0
SX2_k127_3161284_4 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 511.0
SX2_k127_3161284_5 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 504.0
SX2_k127_3161284_6 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 485.0
SX2_k127_3161284_7 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 482.0
SX2_k127_3161284_8 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 445.0
SX2_k127_3161284_9 Cell cycle protein K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 353.0
SX2_k127_3186088_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 458.0
SX2_k127_3186088_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 408.0
SX2_k127_3186088_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 292.0
SX2_k127_3186088_3 - - - - 0.00000000000000000000009755 104.0
SX2_k127_3186088_4 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000001995 94.0
SX2_k127_3204631_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 316.0
SX2_k127_3204631_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000006656 201.0
SX2_k127_3204631_3 Ami_3 K01448 - 3.5.1.28 0.00001126 49.0
SX2_k127_3208589_0 Zinc dependent phospholipase C - - - 0.0000000000000000000000000000000000000000000000000000000000000000002599 242.0
SX2_k127_3208589_1 Ankyrin repeats (3 copies) - - - 0.0000000000000000003284 91.0
SX2_k127_3208589_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000005327 86.0
SX2_k127_3215458_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000005349 152.0
SX2_k127_3235477_0 Proposed homoserine kinase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 460.0
SX2_k127_3235477_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 370.0
SX2_k127_3246586_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 464.0
SX2_k127_3246586_1 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007394 254.0
SX2_k127_3246586_2 PFAM Peptidase M23 K21471 - - 0.0000000000000000000000000000000000000000000004795 181.0
SX2_k127_3246586_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000147 173.0
SX2_k127_3246586_4 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000001836 134.0
SX2_k127_3246586_5 MMPL family K07003 - - 0.000000000000000000000000000002142 122.0
SX2_k127_3248183_0 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000001454 159.0
SX2_k127_3248183_1 guanyl-nucleotide exchange factor activity K03286,K20276 - - 0.000000000000000000000000000002426 131.0
SX2_k127_3248183_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000003232 69.0
SX2_k127_3256774_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 541.0
SX2_k127_3256774_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 503.0
SX2_k127_3256774_2 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000357 121.0
SX2_k127_3256774_3 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000009064 109.0
SX2_k127_3256774_4 cytochrome c biogenesis protein K07399 - - 0.0000000001201 72.0
SX2_k127_3276595_0 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 505.0
SX2_k127_3276595_1 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 435.0
SX2_k127_3276595_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 384.0
SX2_k127_3276595_3 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 332.0
SX2_k127_3276595_4 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000002343 204.0
SX2_k127_3276595_5 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.0000000000000000000000000000001775 134.0
SX2_k127_3276595_6 PFAM alpha beta hydrolase fold K02170 - 3.1.1.85 0.00000000000000000001175 101.0
SX2_k127_3276595_7 E3 Ubiquitin ligase - - - 0.00000000000008307 83.0
SX2_k127_3324747_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 550.0
SX2_k127_3324747_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 391.0
SX2_k127_3324747_10 biosynthesis protein ThiH K03150 - 4.1.99.19 0.000000000000000005032 87.0
SX2_k127_3324747_11 ThiS family K03154 - - 0.000000000001086 70.0
SX2_k127_3324747_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 355.0
SX2_k127_3324747_3 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 337.0
SX2_k127_3324747_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 322.0
SX2_k127_3324747_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
SX2_k127_3324747_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000001449 247.0
SX2_k127_3324747_7 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000003497 201.0
SX2_k127_3324747_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000001757 184.0
SX2_k127_3324747_9 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000001078 121.0
SX2_k127_3328990_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 578.0
SX2_k127_3328990_1 hydrolase, family 3 K01207 - 3.2.1.52 0.000000000000000000000000000000000003444 151.0
SX2_k127_3328990_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000007365 81.0
SX2_k127_3377553_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 403.0
SX2_k127_3377553_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000003157 211.0
SX2_k127_3377553_2 protein conserved in bacteria K09931 - - 0.00000000000000000000000000000000008873 139.0
SX2_k127_3377553_3 Protein of unknown function (DUF3343) - - - 0.0000004119 54.0
SX2_k127_3392148_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K15230,K15233 - 2.3.3.8,6.2.1.5 0.0 1045.0
SX2_k127_3392148_1 succinate-CoA ligase activity K15231,K15232 - 2.3.3.8,6.2.1.18 2.975e-210 659.0
SX2_k127_3392148_2 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000532 177.0
SX2_k127_33928_0 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000176 295.0
SX2_k127_33928_1 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000007907 199.0
SX2_k127_33928_2 PFAM Haloacid dehalogenase domain protein hydrolase K01091 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 0.000000000000000000000000000000000000008246 153.0
SX2_k127_3398360_0 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000007065 205.0
SX2_k127_3398360_1 tigr00255 - - - 0.000000000000000000000000000000000000000000000000000006359 201.0
SX2_k127_3398360_2 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000000006227 160.0
SX2_k127_3398360_3 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000004725 98.0
SX2_k127_3398360_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000004594 71.0
SX2_k127_3424350_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 393.0
SX2_k127_3424350_1 Ankyrin repeats (3 copies) - - - 0.0000000000000000000000001453 114.0
SX2_k127_3424350_2 peptidyl-tyrosine sulfation - - - 0.0000133 54.0
SX2_k127_3444353_0 Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000005274 207.0
SX2_k127_3444353_1 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000003317 146.0
SX2_k127_3444353_2 Uncharacterized conserved protein (DUF2304) - - - 0.0000000004444 65.0
SX2_k127_3456914_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 420.0
SX2_k127_3456914_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 331.0
SX2_k127_3473147_0 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 386.0
SX2_k127_3482941_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 610.0
SX2_k127_3482941_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 454.0
SX2_k127_3482941_10 Psort location Cytoplasmic, score K07816 - 2.7.6.5 0.0000000005673 69.0
SX2_k127_3482941_11 beta-lactamase activity K07126 - - 0.000001178 60.0
SX2_k127_3482941_12 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000001373 50.0
SX2_k127_3482941_2 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 362.0
SX2_k127_3482941_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000001385 184.0
SX2_k127_3482941_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000006547 175.0
SX2_k127_3482941_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000003491 108.0
SX2_k127_3482941_6 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000002917 93.0
SX2_k127_3482941_7 COG0848 Biopolymer transport protein - - - 0.0000000000000000004008 93.0
SX2_k127_3482941_8 Hsp20/alpha crystallin family K13993 - - 0.000000000000008372 81.0
SX2_k127_3482941_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000001805 86.0
SX2_k127_3551685_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 344.0
SX2_k127_3551685_1 Rubrerythrin K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 291.0
SX2_k127_3551685_2 2-keto-4-pentenoate hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000359 216.0
SX2_k127_3551685_3 monooxygenase activity - - - 0.000000000000000000000005375 107.0
SX2_k127_3551685_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000002271 101.0
SX2_k127_3551685_5 domain, Protein - - - 0.0000000000000000001332 96.0
SX2_k127_3551685_6 peptidyl-tyrosine sulfation - - - 0.000000000000008197 82.0
SX2_k127_3551685_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.000007246 56.0
SX2_k127_3557301_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 601.0
SX2_k127_3557301_1 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 297.0
SX2_k127_3566398_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 439.0
SX2_k127_3566398_1 Phosphorylase superfamily K00757 - 2.4.2.3 0.00000000000000000000002397 102.0
SX2_k127_3566398_2 Histidine phosphatase superfamily (branch 1) K08296 - - 0.00000000000000000000002608 105.0
SX2_k127_3566398_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000003988 56.0
SX2_k127_3590338_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 511.0
SX2_k127_3590338_1 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 451.0
SX2_k127_3590338_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 447.0
SX2_k127_3590338_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 295.0
SX2_k127_3590338_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 288.0
SX2_k127_3590338_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002865 276.0
SX2_k127_3590338_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 254.0
SX2_k127_3590338_7 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
SX2_k127_3590338_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000003269 117.0
SX2_k127_3590338_9 50S ribosomal protein L31 K02909 - - 0.0000000000000000000000001398 106.0
SX2_k127_3613326_0 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 457.0
SX2_k127_3613326_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 324.0
SX2_k127_3613326_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 288.0
SX2_k127_3679480_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000001679 259.0
SX2_k127_3679480_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000004406 224.0
SX2_k127_3679480_2 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000000000000000000000007199 217.0
SX2_k127_3679480_3 HEPN domain - - - 0.00000000000000000002017 96.0
SX2_k127_3679480_4 Sigma-54 interaction domain K07714 - - 0.000000000000000004197 86.0
SX2_k127_3685474_0 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 420.0
SX2_k127_3685474_1 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.000000000000000005225 90.0
SX2_k127_3685474_2 Rubrerythrin - - - 0.0000007764 55.0
SX2_k127_3719771_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000547 297.0
SX2_k127_3755496_0 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 542.0
SX2_k127_3755496_1 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 470.0
SX2_k127_3755496_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 457.0
SX2_k127_3755496_3 peroxidase activity K00435 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003071 269.0
SX2_k127_3755496_4 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.0000000000000000000000000000000000002209 151.0
SX2_k127_3755496_5 Belongs to the UPF0178 family - - - 0.00000000000000000000000000000000001712 140.0
SX2_k127_3755496_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000001305 123.0
SX2_k127_3755496_7 - - - - 0.00000000000000006632 84.0
SX2_k127_3770116_0 protein-glutamate methylesterase activity K03412,K13924 - 2.1.1.80,3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 395.0
SX2_k127_3770116_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 397.0
SX2_k127_3770116_2 PFAM chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000002306 254.0
SX2_k127_3770116_3 Methylase of chemotaxis methyl-accepting K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000645 223.0
SX2_k127_3770116_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000003188 190.0
SX2_k127_3770116_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis - - - 0.000000000000000000000000000000000000000000004552 169.0
SX2_k127_3770116_6 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000001152 151.0
SX2_k127_3816695_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 604.0
SX2_k127_3816695_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 464.0
SX2_k127_3816695_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 296.0
SX2_k127_3816695_3 RNA pseudouridylate synthase K06181 - 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000003966 245.0
SX2_k127_3816695_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000008919 243.0
SX2_k127_3816695_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000007367 141.0
SX2_k127_3816695_6 Rhodanese Homology Domain - - - 0.000000000000000000000002726 108.0
SX2_k127_3816695_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000005864 91.0
SX2_k127_3818900_0 carbon starvation protein CstA K06200 - - 6.041e-207 652.0
SX2_k127_3818900_1 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 507.0
SX2_k127_3818900_10 Tetratricopeptide repeat - - - 0.0000004916 57.0
SX2_k127_3818900_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.00005384 48.0
SX2_k127_3818900_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 427.0
SX2_k127_3818900_3 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 400.0
SX2_k127_3818900_4 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000003003 219.0
SX2_k127_3818900_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000002058 191.0
SX2_k127_3818900_6 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.00000000000000000000000000000000000000000000000001451 202.0
SX2_k127_3818900_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000001028 118.0
SX2_k127_3818900_8 ResB-like family - - - 0.00000000000000000001056 104.0
SX2_k127_3818900_9 Belongs to the UPF0235 family K09131 - - 0.0000000000000002184 83.0
SX2_k127_3838256_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1089.0
SX2_k127_3838256_2 Response regulator receiver domain protein K22010 - - 0.0000000000000000000000000000000000000000005654 164.0
SX2_k127_3838256_3 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000003128 142.0
SX2_k127_3838256_4 PFAM PEGA domain protein - - - 0.0000000000000000000000000000001511 134.0
SX2_k127_3838256_5 PFAM Bacterial extracellular solute-binding - - - 0.000001691 51.0
SX2_k127_3861160_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.49e-198 626.0
SX2_k127_3861160_1 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 363.0
SX2_k127_3861160_2 PFAM Cysteine-rich region, CCG K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 298.0
SX2_k127_3861160_3 Fumarase C-terminus K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 257.0
SX2_k127_3861160_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000911 120.0
SX2_k127_3861160_5 HEPN domain - - - 0.0000000000000001861 84.0
SX2_k127_3861160_6 HNH endonuclease - - - 0.0000000000008182 74.0
SX2_k127_3861160_7 Protein of unknown function DUF262 - - - 0.000002597 53.0
SX2_k127_3861160_8 PFAM DNA polymerase, beta domain protein region - - - 0.000003105 54.0
SX2_k127_387393_0 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 326.0
SX2_k127_387393_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 294.0
SX2_k127_3907247_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 368.0
SX2_k127_3907247_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000002191 186.0
SX2_k127_3907247_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000001009 180.0
SX2_k127_3924077_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 472.0
SX2_k127_3924077_1 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 316.0
SX2_k127_3924077_2 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000006171 194.0
SX2_k127_3924077_3 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000026 162.0
SX2_k127_3932832_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2049.0
SX2_k127_3932832_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.792e-314 975.0
SX2_k127_3932832_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000006728 157.0
SX2_k127_3932832_11 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000001617 137.0
SX2_k127_3932832_12 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000004157 87.0
SX2_k127_3932832_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000003809 69.0
SX2_k127_3932832_14 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000002727 63.0
SX2_k127_3932832_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 2.566e-267 834.0
SX2_k127_3932832_3 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 5.216e-234 736.0
SX2_k127_3932832_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 287.0
SX2_k127_3932832_5 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003792 264.0
SX2_k127_3932832_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000001859 246.0
SX2_k127_3932832_7 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002888 221.0
SX2_k127_3932832_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000002111 212.0
SX2_k127_3932832_9 Ribosomal protein L11/L12 K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001262 200.0
SX2_k127_3971777_0 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 455.0
SX2_k127_3971777_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000002373 114.0
SX2_k127_4030662_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 347.0
SX2_k127_4030662_1 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009148 264.0
SX2_k127_4030662_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000001086 245.0
SX2_k127_4030662_3 PFAM 4Fe-4S binding domain - - - 0.0000000000000000000000000000000007236 132.0
SX2_k127_4030662_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000007597 131.0
SX2_k127_4030662_5 Protein conserved in bacteria K09922 - - 0.000000000000000000003175 93.0
SX2_k127_4030662_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000005563 83.0
SX2_k127_4030662_7 Glutaredoxin K03676 - - 0.0000002157 54.0
SX2_k127_4056832_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 539.0
SX2_k127_4056832_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 500.0
SX2_k127_4056832_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000001195 173.0
SX2_k127_4056832_11 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000181 150.0
SX2_k127_4056832_12 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000006163 117.0
SX2_k127_4056832_13 - - - - 0.000000000000000000000001814 105.0
SX2_k127_4056832_14 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000604 105.0
SX2_k127_4056832_15 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000001391 101.0
SX2_k127_4056832_16 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000002538 104.0
SX2_k127_4056832_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 370.0
SX2_k127_4056832_3 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 293.0
SX2_k127_4056832_4 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000003041 268.0
SX2_k127_4056832_5 regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000003279 243.0
SX2_k127_4056832_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000002247 231.0
SX2_k127_4056832_7 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000009925 233.0
SX2_k127_4056832_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000001427 204.0
SX2_k127_4056832_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000005209 199.0
SX2_k127_4074799_0 NmrA-like family K01784,K02473,K03274 - 5.1.3.2,5.1.3.20,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 399.0
SX2_k127_4074799_1 PFAM methyltransferase - - - 0.000000000000000000000000000000000000009572 158.0
SX2_k127_4074799_2 Bifunctional protein K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000002111 145.0
SX2_k127_4074799_3 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000000000000000000000000000000003685 145.0
SX2_k127_4074799_4 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000002483 76.0
SX2_k127_4080834_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 484.0
SX2_k127_4080834_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 294.0
SX2_k127_4080834_2 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001504 259.0
SX2_k127_4080834_3 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000001005 143.0
SX2_k127_4100001_0 biotin synthase activity K01012,K04653 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 331.0
SX2_k127_4100001_1 Biotin and Thiamin Synthesis associated domain - - - 0.00000000000000000000000001154 112.0
SX2_k127_4113086_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 503.0
SX2_k127_4113086_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 297.0
SX2_k127_4113086_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000514 202.0
SX2_k127_4181256_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.325e-196 622.0
SX2_k127_4181256_1 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000002313 229.0
SX2_k127_4181256_2 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000002531 212.0
SX2_k127_4181256_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000576 189.0
SX2_k127_4181256_4 acetyl xylan esterase K01060 - 3.1.1.41 0.00000000000000000000003212 111.0
SX2_k127_4224564_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004577 258.0
SX2_k127_4224564_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000009382 226.0
SX2_k127_4224564_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000003381 228.0
SX2_k127_4224564_3 RNA methyltransferase K09761 - 2.1.1.193 0.00000000000000000000000000000000000000004041 160.0
SX2_k127_4224564_4 sequence-specific DNA binding - - - 0.0000000000000000000000000014 116.0
SX2_k127_4224564_5 YGGT family K02221 - - 0.000000000000001825 77.0
SX2_k127_4224564_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07775 - - 0.00005465 50.0
SX2_k127_4224564_7 PilZ domain K02676 - - 0.0002986 51.0
SX2_k127_4288844_0 Pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 332.0
SX2_k127_4288844_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000001736 230.0
SX2_k127_4288844_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000001168 207.0
SX2_k127_4288844_3 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000003081 146.0
SX2_k127_4288844_4 - - - - 0.000000000000000000000000000000005145 141.0
SX2_k127_4288844_5 Tetratricopeptide repeat - - - 0.00000000002251 72.0
SX2_k127_4292877_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 570.0
SX2_k127_4292877_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 442.0
SX2_k127_4292877_10 DUF218 domain - - - 0.0000000000000000000000005642 113.0
SX2_k127_4292877_11 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000004158 100.0
SX2_k127_4292877_2 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 407.0
SX2_k127_4292877_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 359.0
SX2_k127_4292877_4 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 288.0
SX2_k127_4292877_5 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000006349 255.0
SX2_k127_4292877_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000001139 242.0
SX2_k127_4292877_7 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000003195 222.0
SX2_k127_4292877_8 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000003203 149.0
SX2_k127_4292877_9 Could be involved in septation K06412 - - 0.000000000000000000000000007213 114.0
SX2_k127_4318515_0 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 303.0
SX2_k127_4318515_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000001353 229.0
SX2_k127_4318515_2 translation initiation factor activity K03699 - - 0.0000000000000000000000000000000000000000000002833 176.0
SX2_k127_4318515_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000001466 112.0
SX2_k127_4318515_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000006322 113.0
SX2_k127_4318515_5 Putative regulatory protein - - - 0.0000000000000000000002368 98.0
SX2_k127_4318515_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000008754 73.0
SX2_k127_4318515_8 - - - - 0.0000001658 55.0
SX2_k127_4318515_9 - - - - 0.00001903 49.0
SX2_k127_4321332_0 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 359.0
SX2_k127_4321332_1 calcium, potassium:sodium antiporter activity K07301 - - 0.0000000000000000000000000000000000309 142.0
SX2_k127_4321332_2 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000005784 139.0
SX2_k127_4321332_3 FecR protein - - - 0.000003771 58.0
SX2_k127_4321332_4 Regulatory protein - - - 0.0002845 49.0
SX2_k127_4326697_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.163e-259 811.0
SX2_k127_4326697_1 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000003353 224.0
SX2_k127_4326697_2 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000969 163.0
SX2_k127_4326697_3 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000001371 132.0
SX2_k127_4326697_4 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000001258 118.0
SX2_k127_4326697_5 photosynthesis - - - 0.000000002478 64.0
SX2_k127_4328571_0 penicillin-binding protein K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 515.0
SX2_k127_4328571_1 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 462.0
SX2_k127_4328571_2 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000003797 175.0
SX2_k127_4328571_3 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000003189 142.0
SX2_k127_4328571_4 Methyl-accepting chemotaxis protein (MCP) signaling domain - - - 0.0000000002795 68.0
SX2_k127_4328571_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000002078 56.0
SX2_k127_4328814_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004299 258.0
SX2_k127_4328814_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000001629 143.0
SX2_k127_4328814_2 - - - - 0.0004457 53.0
SX2_k127_4353595_0 C4-dicarboxylate transporter malic acid transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 322.0
SX2_k127_4353595_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000001663 203.0
SX2_k127_4437026_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 581.0
SX2_k127_4437026_1 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 321.0
SX2_k127_4437026_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000974 207.0
SX2_k127_4437026_3 riboflavin synthase alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000003812 191.0
SX2_k127_4437026_4 GAF domain - - - 0.0000000000000000000000000000000000000000000000000245 194.0
SX2_k127_4437026_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000002491 125.0
SX2_k127_4437026_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000111 74.0
SX2_k127_4492389_0 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009557 269.0
SX2_k127_4492389_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009859 253.0
SX2_k127_4492389_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000001177 246.0
SX2_k127_4492389_3 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000009216 242.0
SX2_k127_4492389_4 FecR protein - - - 0.000000000000000000000002061 113.0
SX2_k127_4492389_5 Cobalt transport protein K02008 - - 0.00000000000000000000003754 111.0
SX2_k127_4492389_6 FecR protein - - - 0.000000005776 64.0
SX2_k127_4492389_7 PilZ domain - - - 0.000000008114 61.0
SX2_k127_4509815_0 Molybdopterin oxidoreductase K00370,K17050 - 1.7.5.1 0.0 1219.0
SX2_k127_4509815_1 General secretory system II, protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 614.0
SX2_k127_4509815_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 299.0
SX2_k127_4509815_3 Sensor histidine kinase, HAMP domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 307.0
SX2_k127_4509815_4 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000004232 159.0
SX2_k127_4509815_5 Cytochrome b/b6/petB - - - 0.00000000000000000000000007374 117.0
SX2_k127_4509815_6 Cytochrome c - - - 0.00000000000000000005496 96.0
SX2_k127_4509815_7 PFAM Fimbrial assembly family protein K02663 - - 0.00000000447 64.0
SX2_k127_4509815_9 Pilus assembly protein K02662 - - 0.00002707 55.0
SX2_k127_4515815_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 486.0
SX2_k127_4515815_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 452.0
SX2_k127_4515815_10 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000009004 197.0
SX2_k127_4515815_11 MafB19-like deaminase K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000008597 173.0
SX2_k127_4515815_12 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000007553 180.0
SX2_k127_4515815_13 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000009336 164.0
SX2_k127_4515815_14 - - - - 0.0000000000000000000000000000000000000002998 163.0
SX2_k127_4515815_15 Thermostable hemolysin - - - 0.000000000000000000000001718 112.0
SX2_k127_4515815_16 PFAM Penicillinase repressor - - - 0.0000000000000000000409 95.0
SX2_k127_4515815_17 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.000000000000000008422 89.0
SX2_k127_4515815_19 4Fe-4S single cluster domain K22227 - - 0.00000000000000006591 93.0
SX2_k127_4515815_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 343.0
SX2_k127_4515815_20 Thermostable hemolysin - - - 0.0000000000000001379 88.0
SX2_k127_4515815_21 BlaR1 peptidase M56 - - - 0.000000000005812 76.0
SX2_k127_4515815_22 - - - - 0.0002075 48.0
SX2_k127_4515815_3 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 338.0
SX2_k127_4515815_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 312.0
SX2_k127_4515815_5 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 297.0
SX2_k127_4515815_6 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002759 273.0
SX2_k127_4515815_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000002519 226.0
SX2_k127_4515815_8 serine-type endopeptidase activity K09973 - - 0.0000000000000000000000000000000000000000000000000000000003593 212.0
SX2_k127_4515815_9 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000002135 221.0
SX2_k127_4585316_0 General secretory system II, protein E domain protein K02652 - - 6.047e-231 727.0
SX2_k127_4585316_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 492.0
SX2_k127_4585316_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000005688 268.0
SX2_k127_4585316_3 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000003042 96.0
SX2_k127_4656387_0 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006683 280.0
SX2_k127_4656387_1 Protein of unknown function (DUF2400) K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001977 274.0
SX2_k127_4656387_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000001505 227.0
SX2_k127_4701879_0 N-terminal domain of unknown function (DUF4140) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001858 253.0
SX2_k127_4701879_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000008712 140.0
SX2_k127_4701879_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000006107 113.0
SX2_k127_4738709_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1081.0
SX2_k127_4738709_1 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000002314 104.0
SX2_k127_4738709_2 - - - - 0.0000000000000000000002095 101.0
SX2_k127_4738709_3 Domain of unknown function (DUF1858) - - - 0.000000000000000000001683 95.0
SX2_k127_4738709_4 4 iron, 4 sulfur cluster binding - - - 0.000000000000000003681 85.0
SX2_k127_4738709_5 Domain of Unknown function (DUF542) K07322 - - 0.00000000001245 66.0
SX2_k127_4738709_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000008054 52.0
SX2_k127_4752236_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000001619 188.0
SX2_k127_4752236_1 Alginate export - - - 0.000000000000000000000000000000000000000009632 167.0
SX2_k127_4752236_2 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000000000001254 129.0
SX2_k127_4765003_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 479.0
SX2_k127_4765003_1 cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 315.0
SX2_k127_4765003_2 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000002215 90.0
SX2_k127_4765003_3 peptidylprolyl isomerase K03770 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 0.000000000004097 79.0
SX2_k127_4765003_4 - - - - 0.0000000002959 70.0
SX2_k127_48037_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000005216 231.0
SX2_k127_48037_1 E3 Ubiquitin ligase - - - 0.00000000000003207 83.0
SX2_k127_48037_2 PFAM Protein kinase domain - - - 0.000000002453 63.0
SX2_k127_4805771_0 serine threonine protein kinase K12132 - 2.7.11.1 1.515e-198 647.0
SX2_k127_4805771_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 290.0
SX2_k127_4805771_2 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000002263 176.0
SX2_k127_4805771_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000001535 93.0
SX2_k127_4864311_0 TIGRFAM 6-phosphogluconate dehydrogenase, decarboxylating K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 378.0
SX2_k127_4864311_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000002264 220.0
SX2_k127_4864311_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057,K02564 - 3.1.1.31,3.5.99.6 0.0000000000000000000000000000000000000005048 153.0
SX2_k127_4873190_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.189e-298 932.0
SX2_k127_4873190_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.637e-207 653.0
SX2_k127_4873190_2 Radical SAM superfamily K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 394.0
SX2_k127_4873190_3 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.0000000000000000000000004383 110.0
SX2_k127_4873190_4 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000005419 107.0
SX2_k127_4892045_0 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000002108 186.0
SX2_k127_4892045_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000004554 182.0
SX2_k127_4892045_2 PFAM conserved K08316 - 2.1.1.171 0.00000000000000000000000000000000003847 141.0
SX2_k127_4892045_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000003641 118.0
SX2_k127_4892300_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 359.0
SX2_k127_4892300_1 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 318.0
SX2_k127_4892300_2 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 302.0
SX2_k127_4892300_3 Receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 304.0
SX2_k127_4892300_4 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001997 276.0
SX2_k127_4892300_5 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000004522 281.0
SX2_k127_4892300_6 transmembrane signaling receptor activity K03406 - - 0.0000000000000000000000000000001422 138.0
SX2_k127_4892300_7 PFAM response regulator receiver K03413 - - 0.00000000000000000000000009597 111.0
SX2_k127_4892300_8 Sulfurtransferase - - - 0.0000000239 55.0
SX2_k127_4892300_9 PFAM CheW domain protein K03408 - - 0.0000007104 57.0
SX2_k127_4901034_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 471.0
SX2_k127_4901034_1 - - - - 0.0000000009058 69.0
SX2_k127_4908541_0 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000003355 111.0
SX2_k127_4908541_1 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000001201 67.0
SX2_k127_4908541_2 Lipopolysaccharide-assembly - - - 0.000000001735 65.0
SX2_k127_4919660_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.027e-194 614.0
SX2_k127_4919660_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000005664 124.0
SX2_k127_5001475_0 type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 418.0
SX2_k127_5001475_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 349.0
SX2_k127_5001475_2 PFAM N-acetylmuramoyl-L-alanine amidase family 2 - - - 0.00000000000000000000000000000000000000004047 156.0
SX2_k127_5011067_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 535.0
SX2_k127_5011067_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 470.0
SX2_k127_5011067_10 cyclic nucleotide binding K01420,K10914,K21556,K21562 - - 0.0000000000000000000000000000000000128 144.0
SX2_k127_5011067_11 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000000000003077 113.0
SX2_k127_5011067_12 HEAT repeat - - - 0.000000000000000001067 93.0
SX2_k127_5011067_2 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 432.0
SX2_k127_5011067_3 histidine kinase, HAMP K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 331.0
SX2_k127_5011067_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000001031 271.0
SX2_k127_5011067_5 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001235 279.0
SX2_k127_5011067_6 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 268.0
SX2_k127_5011067_7 PFAM Uncharacterised BCR, COG1649 K11931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001607 259.0
SX2_k127_5011067_8 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000001547 221.0
SX2_k127_5011067_9 HEAT repeats - - - 0.000000000000000000000000000000000000001373 166.0
SX2_k127_5033172_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 613.0
SX2_k127_5033172_1 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 557.0
SX2_k127_5033172_10 Cyclic nucleotide-monophosphate binding domain K04739 - - 0.00000000000000000000009343 111.0
SX2_k127_5033172_11 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000002572 88.0
SX2_k127_5033172_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 440.0
SX2_k127_5033172_3 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 403.0
SX2_k127_5033172_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 314.0
SX2_k127_5033172_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003399 285.0
SX2_k127_5033172_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000004362 265.0
SX2_k127_5033172_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005466 261.0
SX2_k127_5033172_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000002048 188.0
SX2_k127_5033172_9 transport system, membrane component - - - 0.00000000000000000000000000000235 122.0
SX2_k127_5034972_0 PFAM Radical SAM - - - 4.586e-201 638.0
SX2_k127_5034972_1 transport system, membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003436 284.0
SX2_k127_50380_0 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 391.0
SX2_k127_50380_1 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 336.0
SX2_k127_50380_2 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000001066 207.0
SX2_k127_50380_3 Yqey-like protein K09117 - - 0.0000000000000000000000000000000003443 136.0
SX2_k127_5051152_0 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000001327 179.0
SX2_k127_5051152_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000006544 130.0
SX2_k127_5051152_3 ResB protein required for cytochrome c biosynthesis K07399 - - 0.00008109 53.0
SX2_k127_5077328_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 322.0
SX2_k127_5077328_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 285.0
SX2_k127_5077328_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003105 275.0
SX2_k127_5077328_4 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.0000000000000000005499 91.0
SX2_k127_5156398_0 AefR-like transcriptional repressor, C-terminal region - - - 0.0000000000000000000000000000000000006355 147.0
SX2_k127_5156398_1 COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - 0.000000000000000000001798 100.0
SX2_k127_5156398_2 response to abiotic stimulus - - - 0.0003154 53.0
SX2_k127_5157118_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 425.0
SX2_k127_5157118_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000005551 235.0
SX2_k127_5157802_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 511.0
SX2_k127_5157802_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 285.0
SX2_k127_5157802_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001137 256.0
SX2_k127_5157802_3 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000000146 96.0
SX2_k127_5174125_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 585.0
SX2_k127_5174125_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000001248 224.0
SX2_k127_5174125_2 Formylmethanofuran dehydrogenase, subunit e - - - 0.0000000000000000000000000000000000000000000000007495 182.0
SX2_k127_5174125_3 PFAM Peptidase S24 S26A S26B, conserved region - - - 0.000000005035 63.0
SX2_k127_5174125_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00009764 46.0
SX2_k127_5195316_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 486.0
SX2_k127_5195316_1 Part of a membrane complex involved in electron transport K00347,K03614 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 390.0
SX2_k127_5195316_10 FMN binding K03612 - - 0.00000000000000000000000000000002538 132.0
SX2_k127_5195316_11 Glutathione peroxidase - - - 0.0000000000000000000000000000001579 132.0
SX2_k127_5195316_12 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000003954 119.0
SX2_k127_5195316_14 glutaredoxin 2 - - - 0.00000000000000002124 85.0
SX2_k127_5195316_15 Tetratricopeptide repeat - - - 0.0000000000000001292 88.0
SX2_k127_5195316_16 histidine kinase, HAMP K13598 - 2.7.13.3 0.0001175 47.0
SX2_k127_5195316_2 Trypsin K08070,K08372 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 340.0
SX2_k127_5195316_3 ResB-like family K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 328.0
SX2_k127_5195316_4 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003761 286.0
SX2_k127_5195316_5 Putative Fe-S cluster K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003161 279.0
SX2_k127_5195316_6 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009377 264.0
SX2_k127_5195316_7 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000003163 239.0
SX2_k127_5195316_8 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000009778 227.0
SX2_k127_5195316_9 Thioredoxin-like - - - 0.00000000000000000000000000000000000000002005 159.0
SX2_k127_5206799_0 Phage tail tape measure protein, TP901 family - - - 0.00000000001269 76.0
SX2_k127_5257698_0 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 367.0
SX2_k127_5266197_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000553 230.0
SX2_k127_5266197_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000002437 218.0
SX2_k127_5266197_2 (Rhomboid) family K07059 - - 0.000000000000000000000000000000000000000000000000000000002372 206.0
SX2_k127_5266197_3 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000003082 127.0
SX2_k127_5266197_4 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000001094 67.0
SX2_k127_5288884_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 4.433e-253 804.0
SX2_k127_5288884_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 447.0
SX2_k127_5288884_2 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 355.0
SX2_k127_5288884_3 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003427 277.0
SX2_k127_5288884_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000001459 233.0
SX2_k127_5288884_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000003524 165.0
SX2_k127_5288884_6 cytochrome complex assembly - - - 0.000000003532 65.0
SX2_k127_5328783_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 591.0
SX2_k127_5328783_1 Belongs to the complex I 75 kDa subunit family K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 605.0
SX2_k127_5328783_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 483.0
SX2_k127_5328783_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 312.0
SX2_k127_5328783_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000005319 226.0
SX2_k127_5328783_5 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000008946 224.0
SX2_k127_5328783_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000005431 182.0
SX2_k127_5328783_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000001554 157.0
SX2_k127_5328783_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000118 128.0
SX2_k127_5328783_9 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000004204 117.0
SX2_k127_5352511_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000005803 151.0
SX2_k127_5362305_0 CBS domain containing protein K00974 - 2.7.7.72 1.783e-211 688.0
SX2_k127_5362305_1 2 iron, 2 sulfur cluster binding K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 415.0
SX2_k127_5362305_10 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000001357 87.0
SX2_k127_5362305_11 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000001028 72.0
SX2_k127_5362305_12 SEC-C motif domain protein K07039 - - 0.000000003992 66.0
SX2_k127_5362305_13 Protein of unknown function (DUF2892) - - - 0.000000566 54.0
SX2_k127_5362305_2 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 342.0
SX2_k127_5362305_3 curli production assembly transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 331.0
SX2_k127_5362305_4 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 305.0
SX2_k127_5362305_5 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001601 284.0
SX2_k127_5362305_6 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000003635 269.0
SX2_k127_5362305_7 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000008111 166.0
SX2_k127_5362305_8 Lipoprotein - - - 0.000000000000000000000000000000000000000001181 165.0
SX2_k127_5362305_9 MarR family transcriptional regulator - - - 0.0000000000000000000000000002108 118.0
SX2_k127_5373919_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 6.067e-243 756.0
SX2_k127_5373919_1 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000000000000000000000001715 195.0
SX2_k127_5373919_2 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000002025 194.0
SX2_k127_5373919_3 YacP-like NYN domain K06962 - - 0.000000000001611 74.0
SX2_k127_5373919_4 Domain of unknown function (DUF4105) - - - 0.00000002365 59.0
SX2_k127_5373919_5 to M. xanthus CarD K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.00002354 48.0
SX2_k127_5398678_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 485.0
SX2_k127_5398678_1 cheY-homologous receiver domain - - - 0.00000002821 61.0
SX2_k127_5420880_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 577.0
SX2_k127_5420880_1 - - - - 0.000000000000000000000000000000000000000000000000003171 188.0
SX2_k127_5420880_2 Tetratricopeptide repeat - - - 0.000000000000003539 82.0
SX2_k127_5423253_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 531.0
SX2_k127_5423253_1 cAMP biosynthetic process - - - 0.0000000000000000000009958 110.0
SX2_k127_5423253_2 SMART Tetratricopeptide domain protein - - - 0.0000004227 59.0
SX2_k127_546591_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 406.0
SX2_k127_546591_1 PFAM Major facilitator superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 378.0
SX2_k127_547522_0 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 466.0
SX2_k127_547522_1 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 377.0
SX2_k127_547522_2 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000002065 215.0
SX2_k127_547522_3 PhoQ Sensor - - - 0.00000000000000000000000000000000000001317 162.0
SX2_k127_547522_4 long-chain fatty acid transporting porin activity K07267 - - 0.000000000000000000000000000000008155 142.0
SX2_k127_547522_5 Dodecin K09165 - - 0.0000000000000000001147 90.0
SX2_k127_547522_7 phosphate ion binding - - - 0.000001192 57.0
SX2_k127_547522_8 - - - - 0.000006058 51.0
SX2_k127_5484984_0 Peptidase dimerisation domain K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 370.0
SX2_k127_5484984_1 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 355.0
SX2_k127_5484984_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000002655 164.0
SX2_k127_5484984_3 Domain of unknown function (DUF1736) - - - 0.00000000001673 73.0
SX2_k127_5501441_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 500.0
SX2_k127_5501441_1 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 383.0
SX2_k127_5501441_10 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000005583 115.0
SX2_k127_5501441_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000001979 49.0
SX2_k127_5501441_2 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 301.0
SX2_k127_5501441_3 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 294.0
SX2_k127_5501441_4 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000003982 265.0
SX2_k127_5501441_5 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000003705 232.0
SX2_k127_5501441_6 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000000000003501 209.0
SX2_k127_5501441_7 methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000002329 191.0
SX2_k127_5501441_8 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000005876 132.0
SX2_k127_5501441_9 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000004068 120.0
SX2_k127_5513171_0 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 553.0
SX2_k127_5513171_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 526.0
SX2_k127_5513171_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 360.0
SX2_k127_5513171_3 peptidase M29 K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 360.0
SX2_k127_5513171_4 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000008315 207.0
SX2_k127_5513171_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors - - - 0.00000000000000000000000000000000000000000000000000000003311 209.0
SX2_k127_5513171_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000004939 101.0
SX2_k127_5527120_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 398.0
SX2_k127_5527120_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000004221 227.0
SX2_k127_5537354_0 ABC transporter K06158 - - 2.667e-196 628.0
SX2_k127_5537354_1 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 516.0
SX2_k127_5537354_2 GIY-YIG type nucleases (URI domain) K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 495.0
SX2_k127_5537354_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 366.0
SX2_k127_5537354_4 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 302.0
SX2_k127_5537354_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000003073 224.0
SX2_k127_5537354_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000164 190.0
SX2_k127_5537354_7 - - - - 0.0000000000004387 71.0
SX2_k127_5550933_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 432.0
SX2_k127_5550933_1 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 286.0
SX2_k127_5550933_2 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000003536 100.0
SX2_k127_5557250_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 427.0
SX2_k127_5557250_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 364.0
SX2_k127_5574595_0 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003531 257.0
SX2_k127_5574595_1 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002744 254.0
SX2_k127_5574595_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000001067 203.0
SX2_k127_5574595_3 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000001283 196.0
SX2_k127_5574595_4 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000312 176.0
SX2_k127_5574595_5 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000003461 175.0
SX2_k127_5574595_6 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000002024 174.0
SX2_k127_5574595_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000006617 131.0
SX2_k127_5574595_8 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000002881 94.0
SX2_k127_5574595_9 Belongs to the UPF0434 family K09791 - - 0.0000000000005997 70.0
SX2_k127_5588844_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 559.0
SX2_k127_5588844_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000006359 252.0
SX2_k127_5588844_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009876 234.0
SX2_k127_5618083_0 - - - - 0.000000000000000000000577 111.0
SX2_k127_5618083_1 Putative bacterial lipoprotein (DUF799) K21008 - - 0.000000000004604 74.0
SX2_k127_56415_0 PFAM Isocitrate dehydrogenase NADP-dependent monomeric type K00031 - 1.1.1.42 2.345e-288 898.0
SX2_k127_56415_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.704e-209 676.0
SX2_k127_56415_10 - - - - 0.0000006857 53.0
SX2_k127_56415_11 G8 - - - 0.00008895 54.0
SX2_k127_56415_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000008831 157.0
SX2_k127_56415_3 Monomeric isocitrate dehydrogenase - - - 0.0000000000000000000000000000000000001912 141.0
SX2_k127_56415_4 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000004237 139.0
SX2_k127_56415_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000786 132.0
SX2_k127_56415_6 Regulatory protein - - - 0.0000000000000000000001029 102.0
SX2_k127_56415_7 - - - - 0.0000000000001298 83.0
SX2_k127_56415_8 - - - - 0.00000000008084 75.0
SX2_k127_56415_9 - - - - 0.000000002993 69.0
SX2_k127_5664401_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.403e-288 909.0
SX2_k127_5664401_1 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009174 278.0
SX2_k127_5664401_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000007711 233.0
SX2_k127_5664401_3 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor K09776 - - 0.0000000000000000000000000000000000000000000000000001483 190.0
SX2_k127_5664401_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000002865 67.0
SX2_k127_5664875_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 439.0
SX2_k127_5664875_1 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 335.0
SX2_k127_5664875_10 Thiamine-binding protein - - - 0.000000000000000000000000000000000008244 138.0
SX2_k127_5664875_11 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000001144 136.0
SX2_k127_5664875_12 copper resistance - - - 0.000000000000000000000001104 109.0
SX2_k127_5664875_13 Rubrerythrin - - - 0.000000002436 59.0
SX2_k127_5664875_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 313.0
SX2_k127_5664875_3 macromolecule localization K01421,K01992,K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 296.0
SX2_k127_5664875_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001658 278.0
SX2_k127_5664875_5 PSP1 C-terminal domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005258 266.0
SX2_k127_5664875_6 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000007127 248.0
SX2_k127_5664875_7 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000002452 221.0
SX2_k127_5664875_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000002277 195.0
SX2_k127_5664875_9 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000002462 177.0
SX2_k127_5674988_0 mismatched DNA binding K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.601e-250 799.0
SX2_k127_5674988_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 9.82e-211 684.0
SX2_k127_5674988_2 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 614.0
SX2_k127_5674988_3 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 296.0
SX2_k127_5674988_4 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004658 280.0
SX2_k127_5674988_5 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003614 258.0
SX2_k127_5674988_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000003198 119.0
SX2_k127_5674988_7 PQQ enzyme repeat - - - 0.0000000000000000000004396 109.0
SX2_k127_5674988_8 FHA domain - - - 0.000000000000000004406 98.0
SX2_k127_5674988_9 Tetratricopeptide repeat - - - 0.0001032 45.0
SX2_k127_5675407_0 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 335.0
SX2_k127_5675407_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000001568 223.0
SX2_k127_5675407_2 - - - - 0.0000000000000000000000000000000000000006855 155.0
SX2_k127_5675407_3 Protein of unknown function (DUF507) - - - 0.0000000000000000004981 90.0
SX2_k127_5675407_4 PFAM Phosphomethylpyrimidine kinase type-1 K00941 - 2.7.1.49,2.7.4.7 0.0000000000001051 76.0
SX2_k127_5675407_5 COG0457 FOG TPR repeat - - - 0.00003139 54.0
SX2_k127_5694792_0 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009973 276.0
SX2_k127_5694792_1 Protein of unknown function (DUF1571) - - - 0.000000000000000000000000000000000000000003073 165.0
SX2_k127_5694792_2 Thioesterase K07107 - - 0.0000000000000000000000000002549 119.0
SX2_k127_5694792_3 Cupin domain - - - 0.000000000000000000002239 97.0
SX2_k127_5694792_4 4Fe-4S dicluster domain - - - 0.00009613 48.0
SX2_k127_5725649_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 386.0
SX2_k127_5725649_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004204 263.0
SX2_k127_5725649_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002439 254.0
SX2_k127_5725649_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000004936 179.0
SX2_k127_5725649_4 - - - - 0.0000000000000002059 82.0
SX2_k127_5725649_5 - - - - 0.000000004906 64.0
SX2_k127_5759842_0 Psort location Cytoplasmic, score K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 344.0
SX2_k127_5759842_1 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000004321 207.0
SX2_k127_5759842_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000008801 60.0
SX2_k127_5781759_0 Sodium:neurotransmitter symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 613.0
SX2_k127_5781759_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 520.0
SX2_k127_5781759_2 Outer membrane protein beta-barrel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 334.0
SX2_k127_5802019_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 337.0
SX2_k127_5802019_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002963 248.0
SX2_k127_5802019_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000005863 227.0
SX2_k127_5802019_3 membrane K07152,K08976 - - 0.00000000000000000000000000000000000000000000001401 173.0
SX2_k127_5802019_4 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000001391 169.0
SX2_k127_5802019_5 heme a metabolic process K02259 - - 0.000000000000000000000000000000000000000002339 167.0
SX2_k127_5802019_6 Cold-Shock Protein K03704 - - 0.0000000000000000000000012 104.0
SX2_k127_5802019_7 Mannose-6-phosphate isomerase - - - 0.000000000003032 71.0
SX2_k127_5809108_0 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 328.0
SX2_k127_5809108_1 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000001607 119.0
SX2_k127_5809108_2 PFAM helix-turn-helix domain protein - - - 0.000000000000000002551 85.0
SX2_k127_5836731_0 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000192 181.0
SX2_k127_5836731_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000001181 111.0
SX2_k127_5856869_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 561.0
SX2_k127_5856869_1 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 485.0
SX2_k127_5873345_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 556.0
SX2_k127_5873345_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 553.0
SX2_k127_5873345_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 300.0
SX2_k127_5873345_11 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000007258 224.0
SX2_k127_5873345_12 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000008775 205.0
SX2_k127_5873345_13 transcription regulator activity K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000000006164 167.0
SX2_k127_5873345_14 Essential cell division protein K03589 - - 0.000000000000000000000000384 115.0
SX2_k127_5873345_15 Cell division protein FtsL - - - 0.0000004804 57.0
SX2_k127_5873345_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 475.0
SX2_k127_5873345_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 429.0
SX2_k127_5873345_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 412.0
SX2_k127_5873345_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 390.0
SX2_k127_5873345_6 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 326.0
SX2_k127_5873345_7 MraW methylase family K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 312.0
SX2_k127_5873345_8 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 306.0
SX2_k127_5873345_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 302.0
SX2_k127_591983_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.051e-262 828.0
SX2_k127_591983_1 General secretory system II, protein E domain protein K02454 - - 2.697e-232 734.0
SX2_k127_591983_10 TIGRFAM tol-pal system protein YbgF - - - 0.000000000000000000002514 104.0
SX2_k127_591983_11 Bacterial regulatory protein, Fis family - - - 0.00000000002147 73.0
SX2_k127_591983_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.23e-222 700.0
SX2_k127_591983_3 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 448.0
SX2_k127_591983_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005674 268.0
SX2_k127_591983_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000001563 196.0
SX2_k127_591983_6 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000001103 172.0
SX2_k127_591983_7 Lysin motif - - - 0.0000000000000000000000000000000000000000001352 173.0
SX2_k127_591983_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000004147 128.0
SX2_k127_591983_9 - - - - 0.00000000000000000000000003426 112.0
SX2_k127_5941722_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.319e-268 838.0
SX2_k127_5941722_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 345.0
SX2_k127_5941722_2 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 339.0
SX2_k127_5941722_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000001255 201.0
SX2_k127_5941722_4 COG NOG14472 non supervised orthologous group - - - 0.0002737 51.0
SX2_k127_6002677_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008668 239.0
SX2_k127_6002677_1 TPR repeat-containing protein - - - 0.0000000000000000000000000001213 125.0
SX2_k127_6002677_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000001139 68.0
SX2_k127_6053193_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 1.159e-214 689.0
SX2_k127_6053193_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 595.0
SX2_k127_6053193_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 324.0
SX2_k127_6053193_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001027 252.0
SX2_k127_6053193_4 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000009077 193.0
SX2_k127_6053193_5 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000002504 155.0
SX2_k127_6053193_6 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000002462 113.0
SX2_k127_6053193_7 PFAM UspA domain protein - - - 0.000000000000000000006076 98.0
SX2_k127_6064461_0 Sel1 repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000004597 169.0
SX2_k127_6064461_1 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000006554 87.0
SX2_k127_610859_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 591.0
SX2_k127_610859_1 fibronectin type III domain protein K06882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 329.0
SX2_k127_610859_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008475 272.0
SX2_k127_610859_3 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008641 276.0
SX2_k127_610859_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001609 272.0
SX2_k127_610859_5 holo-[acyl-carrier-protein] synthase activity K00950,K00997,K01207,K01775,K06133,K06925,K18014 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.6.3,2.7.8.7,3.2.1.52,4.3.1.14,5.1.1.1 0.00000000000000000003235 95.0
SX2_k127_610859_7 peptidyl-tyrosine sulfation - - - 0.0002592 49.0
SX2_k127_631366_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.085e-284 910.0
SX2_k127_631366_1 ABC transporter K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 377.0
SX2_k127_631366_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 346.0
SX2_k127_631366_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000004889 231.0
SX2_k127_631366_4 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000004587 185.0
SX2_k127_631366_5 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000002455 117.0
SX2_k127_653965_0 COG0493 NADPH-dependent glutamate synthase beta chain and K00266 - 1.4.1.13,1.4.1.14 1.088e-203 643.0
SX2_k127_653965_1 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005084 278.0
SX2_k127_653965_2 PFAM response regulator receiver K02483,K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000004611 241.0
SX2_k127_653965_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741,K18701 - 1.20.4.1,2.8.4.2 0.000000000000000000000000002976 116.0
SX2_k127_653965_4 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000002146 118.0
SX2_k127_689398_0 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 578.0
SX2_k127_689398_1 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 385.0
SX2_k127_689398_2 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000002701 183.0
SX2_k127_778338_0 PFAM chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000002674 235.0
SX2_k127_778338_1 histidine kinase HAMP region domain protein K03406,K05874 - - 0.0000000000000000000000000000000000000000000000000008962 194.0
SX2_k127_778338_2 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000001554 123.0
SX2_k127_778338_3 PilZ domain K03406 - - 0.0000000000004076 77.0
SX2_k127_778338_4 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00001077 50.0
SX2_k127_792423_0 - - - - 0.000000000000000000000000000000000000000000000000000000000001141 218.0
SX2_k127_792423_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000006911 89.0
SX2_k127_792423_2 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000002137 58.0
SX2_k127_794636_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.553e-243 762.0
SX2_k127_794636_1 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 337.0
SX2_k127_794636_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 326.0
SX2_k127_794636_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001054 281.0
SX2_k127_794636_4 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000002728 115.0
SX2_k127_794636_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000439 51.0
SX2_k127_797564_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 451.0
SX2_k127_797564_1 EamA-like transporter family - - - 0.00000000000000000000000000000000007761 142.0
SX2_k127_797564_2 PFAM peptidase K21471 - - 0.0000000000000000000004579 105.0
SX2_k127_797564_3 - - - - 0.0000000002748 70.0
SX2_k127_798549_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.353e-245 771.0
SX2_k127_798549_1 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000005118 211.0
SX2_k127_798549_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000001524 149.0
SX2_k127_798549_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.000000001429 59.0
SX2_k127_803524_0 PFAM ABC transporter related K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 294.0
SX2_k127_803524_1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000003472 178.0
SX2_k127_803524_2 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000001865 70.0
SX2_k127_803524_3 Lipopolysaccharide transport periplasmic protein LptA K09774 - - 0.00000000003217 71.0
SX2_k127_803524_4 Lipopolysaccharide-assembly, LptC-related - - - 0.0000000006369 67.0
SX2_k127_803524_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000005989 60.0
SX2_k127_807349_0 PFAM aminotransferase, class I and II K10206 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0010285,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0033362,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 554.0
SX2_k127_807349_1 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001393 233.0
SX2_k127_807349_2 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000008029 146.0
SX2_k127_807349_3 Acyltransferase family - - - 0.00000000000000000000000000000000781 134.0
SX2_k127_807349_4 YHS domain - - - 0.00002197 50.0
SX2_k127_86066_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 517.0
SX2_k127_86066_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 499.0
SX2_k127_86066_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 308.0
SX2_k127_86066_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 286.0
SX2_k127_86066_4 PFAM Stage II sporulation K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004234 262.0
SX2_k127_86066_5 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000002128 104.0
SX2_k127_86066_6 Cytochrome c - - - 0.0000000000000009873 82.0
SX2_k127_86066_7 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000009161 49.0
SX2_k127_873244_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 596.0
SX2_k127_873244_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 555.0
SX2_k127_873244_10 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001115 260.0
SX2_k127_873244_11 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001346 259.0
SX2_k127_873244_12 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000126 228.0
SX2_k127_873244_13 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000001575 214.0
SX2_k127_873244_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001124 216.0
SX2_k127_873244_15 Ribosomal protein L3 K02906 - - 0.00000000000000000000000000000000000000000000000000000000006046 211.0
SX2_k127_873244_16 PFAM sodium K14445 - - 0.000000000000000000000000000000000000000000000000000003124 206.0
SX2_k127_873244_17 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000001409 182.0
SX2_k127_873244_18 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000001181 181.0
SX2_k127_873244_19 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000005651 166.0
SX2_k127_873244_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 413.0
SX2_k127_873244_20 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000007353 167.0
SX2_k127_873244_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000001272 166.0
SX2_k127_873244_22 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001385 156.0
SX2_k127_873244_23 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000005897 147.0
SX2_k127_873244_24 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000009178 145.0
SX2_k127_873244_25 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000165 146.0
SX2_k127_873244_26 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001722 141.0
SX2_k127_873244_27 Mov34 MPN PAD-1 family protein - - - 0.0000000000000000000000000000000001416 138.0
SX2_k127_873244_28 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000000000000000000006592 132.0
SX2_k127_873244_29 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000009889 130.0
SX2_k127_873244_3 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 395.0
SX2_k127_873244_30 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000002568 130.0
SX2_k127_873244_31 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000001501 130.0
SX2_k127_873244_32 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000006508 130.0
SX2_k127_873244_33 Sulfurtransferase TusA - - - 0.0000000000000000000000005058 106.0
SX2_k127_873244_34 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000005982 102.0
SX2_k127_873244_35 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000003144 102.0
SX2_k127_873244_36 NIL - - - 0.000000000000004123 78.0
SX2_k127_873244_37 Ribosomal protein L30 K02907 - - 0.0000000000001476 73.0
SX2_k127_873244_38 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000004189 71.0
SX2_k127_873244_39 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000003364 66.0
SX2_k127_873244_4 Pyridoxal-phosphate dependent enzyme K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 391.0
SX2_k127_873244_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 385.0
SX2_k127_873244_6 Nitrite/Sulfite reductase ferredoxin-like half domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 378.0
SX2_k127_873244_7 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 321.0
SX2_k127_873244_8 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 305.0
SX2_k127_873244_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001825 281.0
SX2_k127_89198_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 612.0
SX2_k127_89198_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000001113 162.0
SX2_k127_89322_0 Glycosyl transferase family 21 K00694 - 2.4.1.12 4.153e-240 762.0
SX2_k127_89322_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 294.0
SX2_k127_89322_2 PFAM TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000009521 253.0
SX2_k127_89322_3 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000004744 191.0
SX2_k127_89322_4 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000002299 184.0
SX2_k127_89322_5 RNA polymerase sigma factor K03088 - - 0.000000000000000000000002111 108.0
SX2_k127_901557_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 318.0
SX2_k127_901557_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 304.0
SX2_k127_901557_2 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000001624 184.0
SX2_k127_901557_3 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000000000000006099 195.0
SX2_k127_901557_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000003055 138.0
SX2_k127_901557_5 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000007146 127.0
SX2_k127_901557_6 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000002108 124.0
SX2_k127_901557_7 Methyltransferase domain - - - 0.0000004332 60.0
SX2_k127_901557_8 TonB family K03646,K03832 - - 0.0005024 51.0
SX2_k127_92862_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1032.0
SX2_k127_92862_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 611.0
SX2_k127_92862_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 310.0
SX2_k127_92862_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000003556 107.0
SX2_k127_92862_4 - - - - 0.000004207 49.0
SX2_k127_92862_5 - - - - 0.0001919 44.0
SX2_k127_935290_0 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000009836 190.0
SX2_k127_935290_1 phosphorelay signal transduction system - - - 0.0000000002376 66.0
SX2_k127_935290_2 metal-dependent phosphohydrolase, HD sub domain - - - 0.0002464 54.0
SX2_k127_955749_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 523.0
SX2_k127_955749_1 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000001613 240.0
SX2_k127_955749_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000001717 204.0
SX2_k127_988587_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 365.0
SX2_k127_988587_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000002715 216.0
SX2_k127_988587_2 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000805 128.0
SX2_k127_988587_3 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000001436 92.0
SX2_k127_988587_4 Predicted membrane protein (DUF2127) - - - 0.0000000000000001907 88.0
SX2_k127_988587_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000006844 68.0