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Overview

ID MAG03654
Name SX3_bin.23
Sample SMP0093
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family JACTUA01
Genus JAJRCM01
Species
Assembly information
Completeness (%) 81.83
Contamination (%) 0.6
GC content (%) 53.0
N50 (bp) 6,467
Genome size (bp) 1,364,916

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1573

Gene name Description KEGG GOs EC E-value Score Sequence
SX3_k127_1016537_0 Replication factor C K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 366.0
SX3_k127_1016537_1 PFAM GHMP kinase K06982 - 2.7.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 298.0
SX3_k127_1016537_2 Pfam:DUF137 K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000003941 251.0
SX3_k127_1016537_3 PFAM methyltransferase - - - 0.000000000000000002763 93.0
SX3_k127_1019805_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 578.0
SX3_k127_1019805_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 377.0
SX3_k127_1019805_2 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 352.0
SX3_k127_1019805_3 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 344.0
SX3_k127_1019805_4 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000005889 227.0
SX3_k127_1019805_5 SigmaK-factor processing regulatory protein BofA - - - 0.00000000004846 66.0
SX3_k127_1030257_0 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 550.0
SX3_k127_1030257_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000138 273.0
SX3_k127_1030257_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000004482 214.0
SX3_k127_1030257_3 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.000000000000000002873 85.0
SX3_k127_1032234_0 Transport of potassium into the cell K03549 - - 7.248e-241 756.0
SX3_k127_1032234_1 acetyltransferase - - - 0.00000000000000000000000000000000000000007829 157.0
SX3_k127_1032234_2 Small multi-drug export protein - - - 0.0000000000000000000000000000000001449 141.0
SX3_k127_1047806_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 336.0
SX3_k127_1047806_1 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 291.0
SX3_k127_1047806_2 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000008474 223.0
SX3_k127_1047806_3 Cobalamin synthesis G C-terminus K02189 - 3.7.1.12 0.000001952 55.0
SX3_k127_1062548_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 567.0
SX3_k127_1062548_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 467.0
SX3_k127_1062548_2 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 411.0
SX3_k127_1062548_3 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.0000000000000000001977 93.0
SX3_k127_1062548_4 - - - - 0.000000000000004477 78.0
SX3_k127_1106346_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.288e-300 927.0
SX3_k127_1106346_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 8.892e-213 664.0
SX3_k127_1106346_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000000005328 132.0
SX3_k127_1106346_11 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000002113 124.0
SX3_k127_1106346_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000513 119.0
SX3_k127_1106346_13 ATP synthase subunit C K02124 - - 0.00000000000000000000002859 100.0
SX3_k127_1106346_14 ATP synthase subunit C K02124 - - 0.0000000000000000000004504 96.0
SX3_k127_1106346_16 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000004341 57.0
SX3_k127_1106346_17 H subunit K02107 - - 0.00000001937 59.0
SX3_k127_1106346_18 PFAM transposase, IS4 family protein - - - 0.0000001396 56.0
SX3_k127_1106346_2 V-type ATPase 116kDa subunit family K02123 - - 8.18e-209 668.0
SX3_k127_1106346_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 568.0
SX3_k127_1106346_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 566.0
SX3_k127_1106346_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 389.0
SX3_k127_1106346_6 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 302.0
SX3_k127_1106346_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 297.0
SX3_k127_1106346_8 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000005174 221.0
SX3_k127_1106346_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000000000000002326 139.0
SX3_k127_1117530_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.321e-250 782.0
SX3_k127_1117530_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 555.0
SX3_k127_1117530_10 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000004025 162.0
SX3_k127_1117530_11 - - - - 0.000000000000000000000000000000001341 136.0
SX3_k127_1117530_12 signal transduction protein with CBS domains K07744 - - 0.0000000000000000000000000007535 113.0
SX3_k127_1117530_13 - - - - 0.00000000000000000000002922 100.0
SX3_k127_1117530_14 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000003342 93.0
SX3_k127_1117530_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 494.0
SX3_k127_1117530_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 461.0
SX3_k127_1117530_4 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 400.0
SX3_k127_1117530_5 TIGRFAM small GTP-binding protein K06943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 393.0
SX3_k127_1117530_6 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 323.0
SX3_k127_1117530_7 E1-E2 ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000003748 248.0
SX3_k127_1117530_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000102 244.0
SX3_k127_1117530_9 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000001199 225.0
SX3_k127_1118990_0 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 376.0
SX3_k127_1118990_1 UV-endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 374.0
SX3_k127_1118990_10 Flavodoxin - GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000001396 98.0
SX3_k127_1118990_11 Flavodoxin domain - - - 0.000000000000000000006194 94.0
SX3_k127_1118990_12 PBS lyase HEAT-like repeat - - - 0.0000000000001035 80.0
SX3_k127_1118990_13 Protease prsW family - - - 0.0000441 51.0
SX3_k127_1118990_2 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 349.0
SX3_k127_1118990_3 PFAM zinc iron permease K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 321.0
SX3_k127_1118990_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000006123 233.0
SX3_k127_1118990_5 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000008784 226.0
SX3_k127_1118990_6 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000004694 152.0
SX3_k127_1118990_7 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000001599 133.0
SX3_k127_1118990_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000000000000000000000000000002733 126.0
SX3_k127_1118990_9 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000000000000000000000000003804 121.0
SX3_k127_1189050_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 5.486e-214 672.0
SX3_k127_1189050_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 8.582e-197 622.0
SX3_k127_1189050_2 Alpha/beta hydrolase family K06889 - - 0.0000000000000000000000000000000000000000000000000002942 193.0
SX3_k127_1220406_0 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 539.0
SX3_k127_1220406_1 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 418.0
SX3_k127_1220406_2 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 407.0
SX3_k127_1220406_3 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 359.0
SX3_k127_1220406_4 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007298 239.0
SX3_k127_1220406_5 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000008811 162.0
SX3_k127_1220406_6 rubredoxin - - - 0.00000000000000000002453 91.0
SX3_k127_1220406_7 Rubredoxin - - - 0.00000000000155 69.0
SX3_k127_1240552_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 6.672e-196 618.0
SX3_k127_1240552_1 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000001638 229.0
SX3_k127_1240552_2 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000003215 220.0
SX3_k127_1240552_3 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000000000001908 187.0
SX3_k127_1242542_0 PFAM peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000004941 235.0
SX3_k127_1242542_1 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000000000000000000000000000000000000123 181.0
SX3_k127_1277046_0 DEAD DEAH box helicase domain protein K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 377.0
SX3_k127_1277046_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 306.0
SX3_k127_1277046_2 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000001067 212.0
SX3_k127_1277046_3 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000001583 84.0
SX3_k127_128525_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009834 285.0
SX3_k127_128525_1 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008383 236.0
SX3_k127_128525_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000000000000000000000000000000000000000001902 228.0
SX3_k127_128525_3 Tripartite tricarboxylate transporter TctA family K08971 - - 0.000000000000000000000000000000000000000000000000000000005359 203.0
SX3_k127_1355925_0 - - - - 0.00000000000000005637 96.0
SX3_k127_1355925_1 PFAM PKD domain containing protein - - - 0.00000005978 66.0
SX3_k127_1370543_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 8.851e-234 736.0
SX3_k127_1370543_1 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 449.0
SX3_k127_1370543_2 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 383.0
SX3_k127_1370543_3 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001507 284.0
SX3_k127_1370543_4 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007588 250.0
SX3_k127_1370543_5 - - - - 0.000000000000000000000000000000000000000000000000000000000159 207.0
SX3_k127_1370543_6 - - - - 0.000000000000000002348 93.0
SX3_k127_1370543_7 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000001198 78.0
SX3_k127_1381611_0 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 420.0
SX3_k127_1381611_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 348.0
SX3_k127_1381611_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 317.0
SX3_k127_1381611_3 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007827 264.0
SX3_k127_1381611_4 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004261 256.0
SX3_k127_1381611_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005781 258.0
SX3_k127_1381611_6 COG0477 Permeases of the major facilitator superfamily K08177 - - 0.00000000000000000000000009198 109.0
SX3_k127_1408981_0 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000001183 182.0
SX3_k127_1408981_1 Flavodoxin - - - 0.000000000000000000000000000000004542 136.0
SX3_k127_1408981_2 Uncharacterised protein family (UPF0153) K06940 - - 0.00001215 53.0
SX3_k127_1425959_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 7.609e-219 689.0
SX3_k127_1425959_1 PFAM Radical SAM domain protein K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 397.0
SX3_k127_1425959_2 PFAM GTP-binding protein HSR1-related K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 366.0
SX3_k127_1425959_3 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 333.0
SX3_k127_1425959_4 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 288.0
SX3_k127_1425959_5 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.000000000000000000000000000000000000000000000000003771 183.0
SX3_k127_1425959_6 Zn-ribbon containing protein K07163 - - 0.000000000000000000000000000000000000000000000001683 176.0
SX3_k127_1425959_7 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.0000000000000000000000000000007664 122.0
SX3_k127_1467034_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 398.0
SX3_k127_1467034_2 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000808 208.0
SX3_k127_1467034_3 - - - - 0.000000000000000000000000000002837 125.0
SX3_k127_1474273_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1255.0
SX3_k127_1474273_1 PFAM CBS domain - - - 3.377e-231 724.0
SX3_k127_1474273_10 - - - - 0.0000000002948 64.0
SX3_k127_1474273_2 Belongs to the UPF0280 family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 289.0
SX3_k127_1474273_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009697 258.0
SX3_k127_1474273_4 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001667 251.0
SX3_k127_1474273_5 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000326 232.0
SX3_k127_1474273_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000001165 173.0
SX3_k127_1474273_7 zinc finger, SWIM - - - 0.0000000000000000000000000000007303 124.0
SX3_k127_1474273_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000001363 104.0
SX3_k127_1474273_9 - - - - 0.0000000000001122 73.0
SX3_k127_1490333_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.887e-268 836.0
SX3_k127_1490333_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 503.0
SX3_k127_1490333_10 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000004154 171.0
SX3_k127_1490333_11 - - - - 0.00000000000000000000000000000000000000000009561 165.0
SX3_k127_1490333_12 PFAM peptidase zinc-dependent K06974 - - 0.00000000000000000000000000000000000000003009 160.0
SX3_k127_1490333_13 Belongs to the UPF0146 family K09713 - - 0.0000000000000000000000000000000000000003521 156.0
SX3_k127_1490333_14 - - - - 0.0000000000000000000000000000000004594 136.0
SX3_k127_1490333_15 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0003881 44.0
SX3_k127_1490333_2 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 480.0
SX3_k127_1490333_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 375.0
SX3_k127_1490333_4 SMART Elongator protein 3 MiaB NifB K15865 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 374.0
SX3_k127_1490333_5 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 331.0
SX3_k127_1490333_6 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 305.0
SX3_k127_1490333_7 methanogen marker protein 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 301.0
SX3_k127_1490333_8 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000002573 241.0
SX3_k127_1490333_9 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000002135 214.0
SX3_k127_1494584_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 3.01e-245 763.0
SX3_k127_1494584_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 558.0
SX3_k127_1494584_10 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000002259 216.0
SX3_k127_1494584_11 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000005551 219.0
SX3_k127_1494584_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000004732 208.0
SX3_k127_1494584_13 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000001722 195.0
SX3_k127_1494584_14 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000004092 191.0
SX3_k127_1494584_15 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.0000000000000000000000000000000000000000000006401 168.0
SX3_k127_1494584_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000000000000000415 128.0
SX3_k127_1494584_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000000002218 91.0
SX3_k127_1494584_18 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000008278 48.0
SX3_k127_1494584_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009773 456.0
SX3_k127_1494584_3 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 408.0
SX3_k127_1494584_4 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 395.0
SX3_k127_1494584_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 387.0
SX3_k127_1494584_6 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 369.0
SX3_k127_1494584_7 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 337.0
SX3_k127_1494584_8 Located on the platform of the 30S subunit K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000005452 235.0
SX3_k127_1494584_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000003258 230.0
SX3_k127_1500428_0 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 501.0
SX3_k127_1500428_1 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 450.0
SX3_k127_1500428_10 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000009182 89.0
SX3_k127_1500428_11 archaeal Zn-finger protein - - - 0.0000000000000003735 81.0
SX3_k127_1500428_12 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.000000000001419 70.0
SX3_k127_1500428_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 310.0
SX3_k127_1500428_3 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001928 270.0
SX3_k127_1500428_4 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004397 245.0
SX3_k127_1500428_5 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000000000000000000000000000000000000000002604 200.0
SX3_k127_1500428_6 Domain of unknown function (DUF371) K09738 - - 0.0000000000000000000000000000000000000002332 154.0
SX3_k127_1500428_7 Belongs to the PDCD5 family K06875 - - 0.0000000000000000000000000000000000001202 145.0
SX3_k127_1500428_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000000000000000001979 114.0
SX3_k127_1500428_9 CRS1_YhbY K07574 - - 0.0000000000000000000174 93.0
SX3_k127_1509878_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.253e-220 692.0
SX3_k127_1509878_1 Protein-export membrane protein SecD K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 597.0
SX3_k127_1509878_10 Protein of unknown function (DUF2551) - - - 0.00000000000000000000000000000000001201 141.0
SX3_k127_1509878_11 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000009428 135.0
SX3_k127_1509878_12 - - - - 0.000000000000000004031 88.0
SX3_k127_1509878_2 Involved in protein export K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 344.0
SX3_k127_1509878_3 Radical SAM ThiC family K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 301.0
SX3_k127_1509878_4 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 286.0
SX3_k127_1509878_5 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000003346 217.0
SX3_k127_1509878_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000004732 220.0
SX3_k127_1509878_7 PFAM HhH-GPD family protein K07457 - - 0.00000000000000000000000000000000000000000000000000000001121 204.0
SX3_k127_1509878_8 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.000000000000000000000000000000000000000002698 162.0
SX3_k127_1509878_9 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000000000000000575 143.0
SX3_k127_151144_0 Proton-conducting membrane transporter K05568 - - 1.04e-217 687.0
SX3_k127_151144_1 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 3.098e-195 615.0
SX3_k127_151144_10 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.000000000000000000000000000000000005087 140.0
SX3_k127_151144_11 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000000000000000001436 136.0
SX3_k127_151144_12 Domain of unknown function (DUF4040) - - - 0.000000000000000000000000249 108.0
SX3_k127_151144_13 Multiple resistance and pH regulation protein F K05570 - - 0.00000000000000000000146 96.0
SX3_k127_151144_14 Membrane bound hydrogenase - - - 0.000000000000000000459 95.0
SX3_k127_151144_2 PFAM respiratory-chain NADH dehydrogenase, subunit 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 383.0
SX3_k127_151144_3 RNA methylase K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 368.0
SX3_k127_151144_4 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18023 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000009883 241.0
SX3_k127_151144_5 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.0000000000000000000000000000000000000000000000000000000000000001968 224.0
SX3_k127_151144_6 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K18017 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000004841 220.0
SX3_k127_151144_7 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.000000000000000000000000000000000000000000000000000001429 194.0
SX3_k127_151144_8 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.00000000000000000000000000000000000000000000006363 173.0
SX3_k127_151144_9 - - - - 0.00000000000000000000000000000000000001039 147.0
SX3_k127_1522994_0 B3/4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 311.0
SX3_k127_1522994_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 318.0
SX3_k127_1522994_2 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000001912 210.0
SX3_k127_1529387_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 500.0
SX3_k127_1529387_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000958 443.0
SX3_k127_1529387_2 HTH-type transcriptional regulatory protein K07728 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 379.0
SX3_k127_1529387_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000001555 217.0
SX3_k127_1529387_4 Anaerobic ribonucleoside-triphosphate reductase - - - 0.00000000000000000000000000000006093 126.0
SX3_k127_1543405_0 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 406.0
SX3_k127_1543405_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 369.0
SX3_k127_1543405_2 Domain of unknown function (DUF1917) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 299.0
SX3_k127_1543405_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000009978 93.0
SX3_k127_1543405_4 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000002258 85.0
SX3_k127_1549296_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 1.137e-314 974.0
SX3_k127_1549296_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 308.0
SX3_k127_1549296_3 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000000000000000000000000000069 193.0
SX3_k127_1549296_4 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000377 130.0
SX3_k127_1549296_5 - - - - 0.000001647 56.0
SX3_k127_1565775_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1700.0
SX3_k127_1565775_1 Uncharacterized protein conserved in archaea (DUF2114) - - - 1.732e-253 788.0
SX3_k127_1565775_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000002737 177.0
SX3_k127_1565775_11 - - - - 0.00000000000000000000000214 104.0
SX3_k127_1565775_2 PFAM Radical SAM domain protein K06937 - - 2.984e-244 761.0
SX3_k127_1565775_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.826e-201 632.0
SX3_k127_1565775_4 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 606.0
SX3_k127_1565775_5 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 507.0
SX3_k127_1565775_6 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 405.0
SX3_k127_1565775_7 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 378.0
SX3_k127_1565775_8 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000005328 211.0
SX3_k127_1565775_9 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.000000000000000000000000000000000000000000000000001354 185.0
SX3_k127_1604247_0 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 458.0
SX3_k127_1604247_1 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.000000000000000000000000000000000000000000000000001736 183.0
SX3_k127_1604247_2 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.0000000000000000000000000000000000000000000000006138 179.0
SX3_k127_1604247_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.000000006951 56.0
SX3_k127_1614455_0 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 404.0
SX3_k127_1614455_1 arsenite transmembrane transporter activity K03893 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001637 289.0
SX3_k127_1614455_2 PFAM glutamate--cysteine ligase, GCS2 - - - 0.00000000000000000000000000000000000000000000000000000000000000003335 228.0
SX3_k127_1614455_3 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000019 194.0
SX3_k127_1614455_4 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000009322 155.0
SX3_k127_1614455_5 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000001348 89.0
SX3_k127_1642018_0 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006636 257.0
SX3_k127_1642018_1 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.00000000000000000000000000000000000000000000000000000009268 200.0
SX3_k127_1642018_2 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000003059 83.0
SX3_k127_1653104_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1479.0
SX3_k127_1653104_1 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 8.006e-230 723.0
SX3_k127_1653104_2 tRNAHis guanylyltransferase - - - 0.0000000000000004197 79.0
SX3_k127_1669026_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 507.0
SX3_k127_1669026_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001661 271.0
SX3_k127_1669026_2 Uncharacterised protein family UPF0058 - - - 0.000000000000000000000000000000000000009785 146.0
SX3_k127_1669026_3 Belongs to the UPF0235 family K09131 - - 0.00000000004234 68.0
SX3_k127_1688475_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1296.0
SX3_k127_1688475_1 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 308.0
SX3_k127_1688475_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 293.0
SX3_k127_1688475_3 PFAM thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000603 260.0
SX3_k127_1688475_4 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001532 256.0
SX3_k127_1688475_5 PBS lyase HEAT-like repeat - - - 0.0000000002063 67.0
SX3_k127_17039_0 Protein-export membrane protein SecD K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 432.0
SX3_k127_17039_1 Involved in protein export K03074 - - 0.0000000000000000000000000000000000000000000001242 169.0
SX3_k127_1709714_0 peptidyl-tyrosine sulfation - - - 1.172e-261 847.0
SX3_k127_1709714_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.128e-227 710.0
SX3_k127_1709714_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 4.26e-196 615.0
SX3_k127_1709714_3 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 578.0
SX3_k127_1709714_4 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 454.0
SX3_k127_1709714_5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 299.0
SX3_k127_1709714_6 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 289.0
SX3_k127_1709714_7 COG0433 Predicted ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000438 263.0
SX3_k127_1709714_8 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000001316 114.0
SX3_k127_1726713_0 Domain of unknown function DUF87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 439.0
SX3_k127_1726713_1 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.000000000000000000000000000000000000000000000000000000000000001182 221.0
SX3_k127_1733986_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 1.438e-242 759.0
SX3_k127_1733986_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 1.853e-203 643.0
SX3_k127_1733986_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 384.0
SX3_k127_1733986_3 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 362.0
SX3_k127_1733986_4 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 331.0
SX3_k127_1733986_5 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 321.0
SX3_k127_1733986_6 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002418 267.0
SX3_k127_1733986_7 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000007087 237.0
SX3_k127_1733986_8 - - - - 0.000000000000001156 87.0
SX3_k127_1733986_9 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.00000000001937 64.0
SX3_k127_1771650_0 AAA-like domain K06915 - - 7.485e-227 714.0
SX3_k127_1771650_1 PFAM formate nitrite transporter K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 379.0
SX3_k127_1771650_2 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 317.0
SX3_k127_1771650_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.00000000000000000000000000000000000000000000000000000000000002049 221.0
SX3_k127_1771650_4 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.0000000000000000000000000000000000000000000000000000000000000383 218.0
SX3_k127_1771650_5 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.0000001912 55.0
SX3_k127_1808844_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 475.0
SX3_k127_1808844_1 PFAM peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 403.0
SX3_k127_1811671_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 5.799e-263 821.0
SX3_k127_1811671_1 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 308.0
SX3_k127_1811671_2 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000676 205.0
SX3_k127_1811671_3 AMP binding - - - 0.000000000000000000000000000000000000000000000001205 184.0
SX3_k127_1811671_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000211 154.0
SX3_k127_1811671_5 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000004857 128.0
SX3_k127_1811671_6 ThiS family K03636 - - 0.000000000000000000000001108 106.0
SX3_k127_1811671_7 Ferredoxin K05337 - - 0.0000000000000000006171 88.0
SX3_k127_1811671_8 PspC domain K03973 - - 0.00000000000000001672 83.0
SX3_k127_1849446_0 DEAD DEAH box helicase K06877 - - 1.583e-290 910.0
SX3_k127_1849446_1 DNA methylase K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 401.0
SX3_k127_1849446_2 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 330.0
SX3_k127_1849446_3 - - - - 0.000000004258 59.0
SX3_k127_1909197_0 PFAM type II secretion system protein E K07332 - - 5.509e-296 918.0
SX3_k127_1909197_1 type II secretion system protein K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 609.0
SX3_k127_1909197_2 KaiC K07331 - - 0.000000000000000000000000000000003023 128.0
SX3_k127_1924965_0 ATP-grasp domain K06913 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 426.0
SX3_k127_1924965_1 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 329.0
SX3_k127_1924965_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000004968 238.0
SX3_k127_1924965_3 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000000000000000000000000000000004623 224.0
SX3_k127_1924965_4 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000000000000000000000000000009923 223.0
SX3_k127_1924965_5 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000008119 153.0
SX3_k127_1924965_6 - - - - 0.000000000000000000417 91.0
SX3_k127_1924965_7 - - - - 0.00000000000002255 79.0
SX3_k127_1924965_8 - - - - 0.00001457 51.0
SX3_k127_1953414_0 AMP-binding enzyme - - - 5.15e-221 692.0
SX3_k127_1953414_1 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 460.0
SX3_k127_1953414_10 - - - - 0.00000000000000000000000000000000000000000000000000001041 204.0
SX3_k127_1953414_11 - - - - 0.0000000000000000000000000000000000000000000000000001003 191.0
SX3_k127_1953414_12 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000002274 187.0
SX3_k127_1953414_13 - - - - 0.00000000000000000000000000000000000000000000000000653 194.0
SX3_k127_1953414_14 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000212 185.0
SX3_k127_1953414_15 Prokaryotic homologs of the JAB domain - - - 0.00000000000000000000000000000000000000000000005353 171.0
SX3_k127_1953414_16 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000007361 177.0
SX3_k127_1953414_17 Belongs to the UPF0216 family K09737 - - 0.00000000000000000000000000000000000000000002187 165.0
SX3_k127_1953414_18 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000000000000000009642 157.0
SX3_k127_1953414_19 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000002837 152.0
SX3_k127_1953414_2 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 434.0
SX3_k127_1953414_20 - - - - 0.00000000000000000000000000000000007465 133.0
SX3_k127_1953414_21 - K00960 - 2.7.7.6 0.00000000000000000000000000000009006 125.0
SX3_k127_1953414_22 - - - - 0.0000000000000000000000000000137 125.0
SX3_k127_1953414_23 Protein of unknown function (DUF2769) - - - 0.0000000000000000000000001887 108.0
SX3_k127_1953414_24 - - - - 0.0000000000000000000001837 104.0
SX3_k127_1953414_25 PFAM peptidase U32 K08303 - - 0.000000000000000000005201 95.0
SX3_k127_1953414_26 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000005351 94.0
SX3_k127_1953414_27 PFAM Radical SAM domain protein - - - 0.0000000000000003099 80.0
SX3_k127_1953414_28 PFAM Radical SAM domain protein - - - 0.000004933 49.0
SX3_k127_1953414_29 FAD dependent oxidoreductase - - - 0.000007442 58.0
SX3_k127_1953414_3 PFAM ABC transporter related K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 387.0
SX3_k127_1953414_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 341.0
SX3_k127_1953414_5 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 321.0
SX3_k127_1953414_6 PFAM SMC domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 302.0
SX3_k127_1953414_7 Sodium hydrogen exchanger K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003936 280.0
SX3_k127_1953414_8 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000005682 216.0
SX3_k127_1953414_9 PFAM TrkA-C domain K07228 - - 0.00000000000000000000000000000000000000000000000000000000006201 208.0
SX3_k127_1982981_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 349.0
SX3_k127_1982981_1 phosphatase activity K07025,K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000002444 173.0
SX3_k127_1982981_2 Mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.0000000000000000000000000000000000005081 143.0
SX3_k127_2066035_0 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 317.0
SX3_k127_2066035_1 ISXO2-like transposase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006618 239.0
SX3_k127_2066035_2 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000005689 129.0
SX3_k127_2070413_0 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003791 273.0
SX3_k127_2070413_1 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.00000000000000000000000000000003521 129.0
SX3_k127_2070413_2 protein possibly involved in aromatic compounds catabolism K02614 - - 0.00000000000000000000000000003392 121.0
SX3_k127_2077832_0 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 420.0
SX3_k127_2077832_1 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 357.0
SX3_k127_2077832_2 PFAM Methyl-coenzyme M reductase, protein D K03422 - - 0.000000000000000000000000000000000000000000000000000104 190.0
SX3_k127_2077832_3 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.000000000000000000000000005388 110.0
SX3_k127_2147708_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 380.0
SX3_k127_2147708_1 phosphohydrolase (DHH superfamily) K07097 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 358.0
SX3_k127_2147708_2 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 328.0
SX3_k127_2147708_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003189 286.0
SX3_k127_2147708_4 - - - - 0.0000000000000000000000000000000000000000000000109 181.0
SX3_k127_2147708_5 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000308 112.0
SX3_k127_2197185_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 413.0
SX3_k127_2197185_1 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 293.0
SX3_k127_2197185_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003903 281.0
SX3_k127_2197185_3 metallopeptidase activity - - - 0.00000000000000006612 86.0
SX3_k127_2197185_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000002073 80.0
SX3_k127_2197185_5 TfoX N-terminal domain - - - 0.0000000000000002405 82.0
SX3_k127_2240084_0 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 297.0
SX3_k127_2240084_1 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000001457 236.0
SX3_k127_2240084_2 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000002056 138.0
SX3_k127_232044_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 489.0
SX3_k127_232044_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000006952 149.0
SX3_k127_2329626_0 sensor histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 291.0
SX3_k127_2329626_1 PFAM dihydropteroate synthase, DHPS - - - 0.000000000000000000000000000000000000003789 147.0
SX3_k127_2329626_2 Protein of unknown function (DUF2769) - - - 0.0000000000000000000000006147 106.0
SX3_k127_233914_0 PFAM TM2 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003629 274.0
SX3_k127_233914_1 PFAM TM2 domain containing protein - - - 0.00000000000000000000000000000000000000000000000000002893 201.0
SX3_k127_233914_2 Belongs to the UPF0248 family K09715 - - 0.0000000000000000002222 90.0
SX3_k127_2343978_0 TIGRFAM small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 362.0
SX3_k127_2343978_1 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004153 266.0
SX3_k127_2354351_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000005165 222.0
SX3_k127_2396195_0 Involved in cell shape control K22222 - - 2.037e-203 639.0
SX3_k127_2396195_1 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 607.0
SX3_k127_2396195_2 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 515.0
SX3_k127_2396195_3 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 349.0
SX3_k127_2396195_4 PFAM Glycosyl transferase family 2 K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004727 279.0
SX3_k127_2396195_5 Uncharacterized membrane protein (DUF2298) - - - 0.000000003205 60.0
SX3_k127_2487443_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 491.0
SX3_k127_2487443_1 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 356.0
SX3_k127_2520864_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 1.316e-275 861.0
SX3_k127_2520864_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 5.39e-200 632.0
SX3_k127_2520864_2 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 338.0
SX3_k127_2520864_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000003608 249.0
SX3_k127_2520864_4 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000000000000000000004776 153.0
SX3_k127_2520864_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000002088 75.0
SX3_k127_2520864_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000001052 66.0
SX3_k127_2540273_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 1.172e-217 679.0
SX3_k127_2540273_1 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 595.0
SX3_k127_2540273_2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 564.0
SX3_k127_2540273_3 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 419.0
SX3_k127_2540273_4 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 354.0
SX3_k127_2540273_6 Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002798 239.0
SX3_k127_2540273_7 catalyzes the formation of a number of methylated intermediates from arsenite and SAM producing trimethylarsine K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000006926 223.0
SX3_k127_2540273_8 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000004092 181.0
SX3_k127_2540273_9 SpoVT / AbrB like domain - - - 0.00000000000000000000000005608 110.0
SX3_k127_2553441_0 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00125 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 587.0
SX3_k127_2553441_1 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 495.0
SX3_k127_2553441_2 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000347 211.0
SX3_k127_2553441_3 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000000006524 226.0
SX3_k127_2553441_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000005007 211.0
SX3_k127_2553441_5 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000001398 112.0
SX3_k127_2553441_6 PFAM TPR repeat-containing protein - - - 0.000000000000008445 81.0
SX3_k127_2556094_0 DEAD DEAH box helicase domain protein K10896 - - 1.562e-299 935.0
SX3_k127_2556094_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 3.079e-264 826.0
SX3_k127_2556094_10 PFAM molybdopterin biosynthesis MoaE K03635,K21142 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.0000000000000000000000000000001763 127.0
SX3_k127_2556094_11 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.0000000000000000002923 92.0
SX3_k127_2556094_12 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000004774 75.0
SX3_k127_2556094_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 545.0
SX3_k127_2556094_3 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 507.0
SX3_k127_2556094_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 295.0
SX3_k127_2556094_5 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001988 258.0
SX3_k127_2556094_6 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000005691 254.0
SX3_k127_2556094_7 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000001117 211.0
SX3_k127_2556094_8 TfuA-like protein - - - 0.000000000000000000000000000000000000000000000121 177.0
SX3_k127_2556094_9 Belongs to the UPF0147 family K09721 - - 0.0000000000000000000000000000000000003061 141.0
SX3_k127_2557734_0 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001067 278.0
SX3_k127_2557734_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003653 263.0
SX3_k127_2557734_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000586 229.0
SX3_k127_2557734_3 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000000000000000005614 194.0
SX3_k127_2557734_4 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000004191 160.0
SX3_k127_2557734_5 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000000001891 127.0
SX3_k127_2557734_6 - - - - 0.00000000000000000000000000001822 119.0
SX3_k127_2557734_7 Binds to the 23S rRNA K02896 - - 0.000000000000000000000000001285 112.0
SX3_k127_2557734_8 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000002484 78.0
SX3_k127_2557734_9 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000006467 72.0
SX3_k127_2593981_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.011e-208 652.0
SX3_k127_2593981_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 571.0
SX3_k127_2593981_10 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000000000000000000000000000004868 151.0
SX3_k127_2593981_11 PBS lyase HEAT-like repeat - - - 0.0000000000000000000003917 108.0
SX3_k127_2593981_12 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000002641 51.0
SX3_k127_2593981_13 COG3364 Zn-ribbon containing protein K07163 - - 0.000006337 57.0
SX3_k127_2593981_2 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 513.0
SX3_k127_2593981_3 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 381.0
SX3_k127_2593981_4 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 305.0
SX3_k127_2593981_5 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001795 274.0
SX3_k127_2593981_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000601 216.0
SX3_k127_2593981_7 PFAM methyltransferase small K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000003747 209.0
SX3_k127_2593981_8 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000000000000000000000000000006611 189.0
SX3_k127_2593981_9 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000000000000000000000000007351 169.0
SX3_k127_2596512_0 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 1.001e-204 643.0
SX3_k127_2596512_1 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005002 281.0
SX3_k127_2596512_2 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003806 281.0
SX3_k127_2596512_3 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.00000000000000000000001114 104.0
SX3_k127_2596512_4 DGC domain - - - 0.0000000000000000000002722 103.0
SX3_k127_2596512_5 Putative zinc ribbon domain - - - 0.00000000000000000177 89.0
SX3_k127_2596512_6 TIR domain - - - 0.00000000000002302 76.0
SX3_k127_2605716_0 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 387.0
SX3_k127_2605716_1 protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000002563 185.0
SX3_k127_2637137_0 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 389.0
SX3_k127_2637137_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000114 189.0
SX3_k127_2637137_2 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000000000000000003 138.0
SX3_k127_2637137_3 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000003116 110.0
SX3_k127_2638854_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 536.0
SX3_k127_2638854_1 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 502.0
SX3_k127_2639531_0 Belongs to the peptidase S16 family - - - 1.186e-198 631.0
SX3_k127_2639531_1 TIGRFAM Chlamydial polymorphic outer membrane protein repeat - - - 0.00000000000003938 82.0
SX3_k127_2672829_0 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 9.648e-196 616.0
SX3_k127_2672829_1 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.000000000000000000000000000000315 128.0
SX3_k127_2672829_2 - - - - 0.0000000000000000000000005112 106.0
SX3_k127_2672829_3 - - - - 0.0000000000000004524 85.0
SX3_k127_2672829_4 PFAM CBS domain containing protein - - - 0.0000000000003417 69.0
SX3_k127_2711280_0 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 311.0
SX3_k127_2711280_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000004268 237.0
SX3_k127_2711280_2 Yip1 domain - - - 0.0000000000000000000000000000000000000000002008 167.0
SX3_k127_2711280_3 COG1361 S-layer domain - - - 0.000000000000000000000000000000000000002295 153.0
SX3_k127_2751194_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 535.0
SX3_k127_2751194_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 511.0
SX3_k127_2751194_2 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 362.0
SX3_k127_2751194_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 346.0
SX3_k127_2751194_4 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000001188 229.0
SX3_k127_2751194_5 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000001415 91.0
SX3_k127_279474_0 in RNase L inhibitor, RLI K06174 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 329.0
SX3_k127_279474_1 RNase L inhibitor, RLI - - - 0.0000000000000000000000000000000000000000000000002531 179.0
SX3_k127_279474_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000004191 96.0
SX3_k127_2804077_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 586.0
SX3_k127_2804077_1 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 544.0
SX3_k127_2804077_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 474.0
SX3_k127_2804077_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 448.0
SX3_k127_2804077_4 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 432.0
SX3_k127_2804077_5 Domain of unknown function (DUF1743) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 417.0
SX3_k127_2804077_6 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 348.0
SX3_k127_2804077_7 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 314.0
SX3_k127_2804077_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11260 - - 0.0000000000000000000000000000000000000000009233 160.0
SX3_k127_2804739_0 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 316.0
SX3_k127_2804739_1 PBS lyase HEAT-like repeat - - - 0.000000000000000002553 92.0
SX3_k127_2830946_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 2.919e-264 824.0
SX3_k127_2830946_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 549.0
SX3_k127_2830946_2 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 344.0
SX3_k127_2830946_3 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 291.0
SX3_k127_2830946_4 PFAM ribosomal protein S8E K02995 - - 0.0000000000000000000000000000000000000000000000006526 177.0
SX3_k127_2830946_5 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.000000000000000000000000000000000000000000004699 167.0
SX3_k127_2830946_6 - - - - 0.00000000000000000000000000000000000000000008833 163.0
SX3_k127_2830946_7 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000000000000000000000000000000000001817 158.0
SX3_k127_2830946_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000000000000000000000003241 123.0
SX3_k127_2830946_9 RNA-binding protein involved in rRNA processing K07569 - - 0.00000000000000000001086 95.0
SX3_k127_2831927_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 4.207e-260 816.0
SX3_k127_2831927_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 316.0
SX3_k127_2831927_2 Family of unknown function (DUF5350) - - - 0.0000000002232 65.0
SX3_k127_2836304_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 402.0
SX3_k127_2836304_1 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 367.0
SX3_k127_2836304_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 322.0
SX3_k127_2836304_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 319.0
SX3_k127_283784_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 385.0
SX3_k127_283784_1 PFAM regulatory protein, ArsR K07721 - - 0.0000000000000000000000000000000000000000000000000000003722 199.0
SX3_k127_283784_2 HEAT repeats - - - 0.000000000000000000000000749 110.0
SX3_k127_283784_3 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000006162 85.0
SX3_k127_283962_0 - - - - 0.00000000000000000000000000001097 121.0
SX3_k127_283962_1 PAS domain - - - 0.000000000000000000000000001926 117.0
SX3_k127_2844522_0 Cellulosome anchoring protein cohesin region - - - 0.0000000000000000000000000000004397 135.0
SX3_k127_2844522_1 Cellulosome anchoring protein cohesin region - - - 0.000000000008609 72.0
SX3_k127_2844522_2 COG1520 FOG WD40-like repeat - - - 0.00000001928 65.0
SX3_k127_2844522_3 - - - - 0.0000001192 57.0
SX3_k127_2844522_4 Pentaxin family K17495 GO:0003674,GO:0003682,GO:0005488,GO:0005575,GO:0005576 - 0.0002759 54.0
SX3_k127_2869433_0 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 463.0
SX3_k127_2869433_1 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000003464 239.0
SX3_k127_2869433_2 NMT1-like family K02051 - - 0.00000001881 57.0
SX3_k127_2915150_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.391e-219 694.0
SX3_k127_2915150_1 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 417.0
SX3_k127_2915150_2 Type II secretion system (T2SS), protein F K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 408.0
SX3_k127_2915150_3 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000000000003666 183.0
SX3_k127_2915150_4 - - - - 0.0000000000000000000000000000005242 126.0
SX3_k127_2915150_5 - - - - 0.000000000000000000575 89.0
SX3_k127_2915150_6 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0001665 45.0
SX3_k127_2921166_0 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 3.487e-243 769.0
SX3_k127_2933723_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1185.0
SX3_k127_2933723_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.023e-247 768.0
SX3_k127_2933723_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 426.0
SX3_k127_2933723_3 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 298.0
SX3_k127_2933723_4 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000006597 231.0
SX3_k127_2933723_5 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000008155 224.0
SX3_k127_2933723_6 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000009962 198.0
SX3_k127_2933723_7 adenyl ribonucleotide binding - - - 0.0000000000000000000000000000000000000000000003299 173.0
SX3_k127_2933723_8 acid binding OB-fold tRNA helicase-type K07463 - - 0.0000000000000000000000000000000000000000003382 162.0
SX3_k127_2933723_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000002298 56.0
SX3_k127_3063784_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 372.0
SX3_k127_3063784_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000006137 154.0
SX3_k127_3075385_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.776e-260 808.0
SX3_k127_3075385_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 486.0
SX3_k127_3086072_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 514.0
SX3_k127_3086072_1 TIGRFAM small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006533 243.0
SX3_k127_3086072_2 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000002941 222.0
SX3_k127_3086072_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.000000000000000000000000000000002555 138.0
SX3_k127_3086072_4 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000003696 65.0
SX3_k127_3131234_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 1.743e-227 706.0
SX3_k127_3131234_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 387.0
SX3_k127_3131234_2 ATP-grasp domain K06914 - 6.3.4.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 379.0
SX3_k127_3131234_3 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 340.0
SX3_k127_3131234_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 258.0
SX3_k127_3131234_5 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000007133 217.0
SX3_k127_3131234_6 - - - - 0.0000000000000000000000000000000000000000001375 166.0
SX3_k127_3131234_7 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000000000000008668 155.0
SX3_k127_3136659_0 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 603.0
SX3_k127_3136659_1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.000000000000000000000000000000000000000002961 157.0
SX3_k127_3136659_2 TPR repeat - - - 0.00000000000000004579 88.0
SX3_k127_3158948_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 5.808e-276 856.0
SX3_k127_3158948_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 590.0
SX3_k127_3158948_2 PFAM dihydropteroate synthase, DHPS - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 507.0
SX3_k127_3158948_3 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008992 452.0
SX3_k127_3158948_4 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 361.0
SX3_k127_3158948_5 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 286.0
SX3_k127_3158948_6 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 291.0
SX3_k127_3158948_7 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000003146 239.0
SX3_k127_3158948_8 Uncharacterized protein, homolog of nitrogen regulatory protein PII - - - 0.00000000000000000000000000000000000000000000000003285 181.0
SX3_k127_3158948_9 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000000002369 145.0
SX3_k127_3200330_0 TIGRFAM formate dehydrogenase family accessory protein FdhD K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001716 279.0
SX3_k127_3200330_1 Domain of unknown function (DUF1890) - - - 0.00000000000000000000000000000000000000000000000003356 184.0
SX3_k127_3200330_2 Domain of unknown function (DUF1894) - - - 0.000000000000000000000000000004248 122.0
SX3_k127_3200330_3 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000004698 74.0
SX3_k127_321356_0 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 338.0
SX3_k127_321356_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 293.0
SX3_k127_321356_2 Protein of unknown function (DUF1722) - - - 0.0000000000000000000001523 100.0
SX3_k127_321356_3 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000959 74.0
SX3_k127_3281696_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 587.0
SX3_k127_3281696_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 549.0
SX3_k127_3281696_2 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 406.0
SX3_k127_3281696_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
SX3_k127_3281696_4 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 286.0
SX3_k127_3281696_5 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000279 269.0
SX3_k127_3281696_6 Helix-turn-helix domain protein K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004953 250.0
SX3_k127_3281696_7 Cysteine-rich small domain K08260 - 3.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000001682 226.0
SX3_k127_3281696_8 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000001145 106.0
SX3_k127_3281792_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005854 269.0
SX3_k127_3281792_1 binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000000000000000003637 170.0
SX3_k127_3281792_2 protein conserved in archaea K09723 - - 0.000000000000000000000000000000000003687 144.0
SX3_k127_3281792_3 Translation initiation factor 2 alpha subunit K03237 - - 0.00000000000000000000000000000000009107 133.0
SX3_k127_3281792_4 PFAM Ribosomal protein S27E K02978 - - 0.0000000000000000000000002159 106.0
SX3_k127_3284232_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 372.0
SX3_k127_3284232_1 - K00960 - 2.7.7.6 0.00000000000000000000005169 101.0
SX3_k127_3284232_2 - - - - 0.000000000000000002174 90.0
SX3_k127_3284232_3 Helix-turn-helix domain - - - 0.00001153 49.0
SX3_k127_3296419_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 420.0
SX3_k127_3296419_1 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 292.0
SX3_k127_3296419_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 289.0
SX3_k127_3296419_3 Flavodoxin - - - 0.000000000000000000000000000000000000000001187 162.0
SX3_k127_3340205_0 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 575.0
SX3_k127_3340205_1 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 464.0
SX3_k127_3340205_2 PFAM metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 287.0
SX3_k127_3340205_3 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000003916 161.0
SX3_k127_3340205_4 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.0000000000000000000000000000000000004263 146.0
SX3_k127_3340205_5 SOS response associated peptidase (SRAP) - - - 0.0000000000000939 73.0
SX3_k127_3340205_6 PFAM YHS domain - - - 0.0000000002284 66.0
SX3_k127_3383167_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 7.723e-241 755.0
SX3_k127_3383167_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 4.545e-240 752.0
SX3_k127_3383167_10 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0002229 48.0
SX3_k127_3383167_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.088e-237 764.0
SX3_k127_3383167_3 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 436.0
SX3_k127_3383167_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 364.0
SX3_k127_3383167_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 318.0
SX3_k127_3383167_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000003456 263.0
SX3_k127_3383167_7 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000002465 178.0
SX3_k127_3383167_8 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000000000000000000000005326 164.0
SX3_k127_3383167_9 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0000000000000000000001127 97.0
SX3_k127_3395967_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1551.0
SX3_k127_3395967_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1206.0
SX3_k127_3395967_10 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 400.0
SX3_k127_3395967_11 PFAM glutamate synthase alpha subunit domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 342.0
SX3_k127_3395967_12 transcription termination protein NusA K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000001182 232.0
SX3_k127_3395967_13 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000003293 164.0
SX3_k127_3395967_14 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000000001876 145.0
SX3_k127_3395967_15 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000417 135.0
SX3_k127_3395967_16 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.00000000000000000000000000000004422 128.0
SX3_k127_3395967_17 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.000000000000000000000433 98.0
SX3_k127_3395967_2 Belongs to the glutamate synthase family - - - 4.19e-270 837.0
SX3_k127_3395967_3 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 606.0
SX3_k127_3395967_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 603.0
SX3_k127_3395967_5 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 575.0
SX3_k127_3395967_6 PFAM glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 563.0
SX3_k127_3395967_7 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 490.0
SX3_k127_3395967_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 408.0
SX3_k127_3395967_9 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 408.0
SX3_k127_341088_0 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 495.0
SX3_k127_341088_1 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000003467 201.0
SX3_k127_341088_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000001759 73.0
SX3_k127_3438845_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 293.0
SX3_k127_3438845_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000004265 233.0
SX3_k127_3438845_2 Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000004053 197.0
SX3_k127_3438845_3 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000000002372 174.0
SX3_k127_3438845_4 Helix-turn-helix domain protein K03627 - - 0.000000000000000000000000000000000000000000001133 170.0
SX3_k127_3438845_5 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000004061 157.0
SX3_k127_3449656_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 378.0
SX3_k127_3449656_1 Amino acid ABC transporter substrate-binding protein, PAAT family K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 347.0
SX3_k127_3449656_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 332.0
SX3_k127_3449656_3 amino acid ABC transporter K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 312.0
SX3_k127_3449656_4 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 306.0
SX3_k127_3449656_5 Amino acid ABC transporter substrate-binding protein, PAAT family K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 305.0
SX3_k127_3449656_6 archaeosine synthase activity K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008753 282.0
SX3_k127_3462122_0 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 325.0
SX3_k127_3462122_1 PFAM Linocin_M18 bacteriocin protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 321.0
SX3_k127_3462122_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 294.0
SX3_k127_3462122_3 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005866 271.0
SX3_k127_3462122_4 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002185 243.0
SX3_k127_3462122_5 chorismate mutase K04093 - 5.4.99.5 0.0000000000000000000000528 102.0
SX3_k127_3462122_6 Rubrerythrin - - - 0.0000000000003476 71.0
SX3_k127_3462122_7 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000001167 65.0
SX3_k127_3466443_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 4.472e-229 719.0
SX3_k127_3466443_1 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 306.0
SX3_k127_3466443_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000003611 239.0
SX3_k127_3466443_3 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000000000000000000000000000000264 196.0
SX3_k127_3466443_4 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000000000000000387 119.0
SX3_k127_3466443_5 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000000000000002632 115.0
SX3_k127_3466443_6 Large family of predicted nucleotide-binding domains K07158 - - 0.0000000000000000000002184 100.0
SX3_k127_3466443_7 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000003755 85.0
SX3_k127_3485410_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.642e-204 642.0
SX3_k127_3485859_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 566.0
SX3_k127_3485859_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 512.0
SX3_k127_3485859_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 391.0
SX3_k127_3485859_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 293.0
SX3_k127_3485859_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 287.0
SX3_k127_3485859_5 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007026 278.0
SX3_k127_3485859_6 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000001618 235.0
SX3_k127_3485859_7 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000523 214.0
SX3_k127_3485859_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000002329 191.0
SX3_k127_3507881_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 445.0
SX3_k127_3507881_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 380.0
SX3_k127_3507881_2 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 356.0
SX3_k127_3507881_3 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006436 300.0
SX3_k127_3507881_4 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000001923 240.0
SX3_k127_3507881_5 structural constituent of ribosome K02962 - - 0.0000000000000008557 78.0
SX3_k127_3507881_6 - - - - 0.0002009 46.0
SX3_k127_3510266_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000004922 233.0
SX3_k127_3510266_1 Uncharacterized protein conserved in archaea (DUF2121) - - - 0.0000000000000000000000000000000000000000000000000008542 190.0
SX3_k127_3510266_3 EamA-like transporter family - - - 0.00000001408 61.0
SX3_k127_3553112_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 1.534e-207 652.0
SX3_k127_3553112_1 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 367.0
SX3_k127_3553112_2 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000003089 124.0
SX3_k127_3553112_3 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.000000000003663 67.0
SX3_k127_3575362_0 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 498.0
SX3_k127_3575362_1 Methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 353.0
SX3_k127_3575362_2 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000002034 245.0
SX3_k127_3575362_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000000000000000000000003442 216.0
SX3_k127_3606102_0 Protein of unknown function (DUF460) K09150 - - 1.293e-228 726.0
SX3_k127_3606102_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 439.0
SX3_k127_3606102_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002565 260.0
SX3_k127_3606102_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 394.0
SX3_k127_3606102_3 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 365.0
SX3_k127_3606102_4 Rio2, N-terminal K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 339.0
SX3_k127_3606102_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 334.0
SX3_k127_3606102_6 Domain of unknown function DUF128 K21640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 323.0
SX3_k127_3606102_7 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 306.0
SX3_k127_3606102_8 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007797 276.0
SX3_k127_3606102_9 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001831 254.0
SX3_k127_3637929_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1159.0
SX3_k127_3637929_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.000000000000000000000000000000000000006069 146.0
SX3_k127_367035_0 COG1940 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 316.0
SX3_k127_3692700_0 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 297.0
SX3_k127_3692700_1 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000035 262.0
SX3_k127_3692700_2 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000007992 229.0
SX3_k127_3692700_3 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000001055 69.0
SX3_k127_3714818_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 547.0
SX3_k127_3717643_0 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 368.0
SX3_k127_3717643_1 - - - - 0.00000000000000000000000000000000004716 144.0
SX3_k127_3717643_2 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000001345 110.0
SX3_k127_3717643_3 archaeal Zn-finger protein - - - 0.0000000000000000000005141 97.0
SX3_k127_3755515_0 Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
SX3_k127_3755515_1 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.0000000000000000000000000000000000000000000000001131 178.0
SX3_k127_3755515_2 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000001892 155.0
SX3_k127_3755515_3 Uncharacterised conserved protein UCP033563 - - - 0.00000000000000000000007094 100.0
SX3_k127_3785673_0 - - - - 0.0000000000000000000000000000000000000000001838 177.0
SX3_k127_3785673_1 - - - - 0.000000000000000000000000000000001901 135.0
SX3_k127_3785673_2 - - - - 0.0000000000000001886 82.0
SX3_k127_3836192_0 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 365.0
SX3_k127_3836192_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 293.0
SX3_k127_3836192_2 Isoprenylcysteine carboxyl methyltransferase - - - 0.00000174 51.0
SX3_k127_3878048_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 5.208e-303 941.0
SX3_k127_3878048_1 Involved in regulation of DNA replication K10725 - - 9.056e-209 655.0
SX3_k127_3878048_10 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 350.0
SX3_k127_3878048_11 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001612 261.0
SX3_k127_3878048_12 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001621 265.0
SX3_k127_3878048_13 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004092 256.0
SX3_k127_3878048_14 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001657 234.0
SX3_k127_3878048_15 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000003121 236.0
SX3_k127_3878048_16 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000001824 225.0
SX3_k127_3878048_17 PFAM Ribonuclease III - - - 0.00000000000000000000000000000000000000000000000000000000001667 213.0
SX3_k127_3878048_18 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000002131 207.0
SX3_k127_3878048_19 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000007544 189.0
SX3_k127_3878048_2 PFAM aminotransferase class V - - - 6.735e-201 631.0
SX3_k127_3878048_20 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000001589 186.0
SX3_k127_3878048_21 Domain of unknown function DUF123 - - - 0.0000000000000000000000000000000000000000001323 163.0
SX3_k127_3878048_22 Peptidase family M23 - - - 0.000000000000000000000000000000000000006654 151.0
SX3_k127_3878048_23 Domain of unknown function (DUF1805) - - - 0.000000000000000000000000000007004 124.0
SX3_k127_3878048_24 - - - - 0.0000000000000000000001455 104.0
SX3_k127_3878048_25 - - - - 0.000000000000000000002797 105.0
SX3_k127_3878048_26 Belongs to the UPF0434 family - - - 0.00000000000000000008307 89.0
SX3_k127_3878048_27 Domain of unknown function (DUF4405) - - - 0.0004608 48.0
SX3_k127_3878048_3 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 1.182e-199 632.0
SX3_k127_3878048_4 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 589.0
SX3_k127_3878048_5 PFAM Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 582.0
SX3_k127_3878048_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 545.0
SX3_k127_3878048_7 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 533.0
SX3_k127_3878048_8 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 489.0
SX3_k127_3878048_9 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 362.0
SX3_k127_3883487_0 - - - - 0.000000000000000000002754 102.0
SX3_k127_3883487_1 - - - - 0.0003166 44.0
SX3_k127_3900460_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 542.0
SX3_k127_3900460_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 427.0
SX3_k127_3900460_2 signal transduction protein with CBS domains K07744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 400.0
SX3_k127_3900460_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 353.0
SX3_k127_3900460_4 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000004034 227.0
SX3_k127_3900460_5 TIGRFAM small GTP-binding protein K06943 - - 0.00000000000000000000000000002454 119.0
SX3_k127_3900460_6 PRC-barrel domain protein - - - 0.0000000000000000003167 89.0
SX3_k127_3968148_0 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 293.0
SX3_k127_3968148_1 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 286.0
SX3_k127_3968148_2 PFAM glutamate--cysteine ligase, GCS2 - - - 0.0000000000000000000000000000000000000000000000000000004794 198.0
SX3_k127_3968148_3 Thioredoxin - - - 0.000000000000000000000000000000000000000000002295 168.0
SX3_k127_3968148_4 aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000001682 125.0
SX3_k127_3981374_0 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000347 173.0
SX3_k127_3981374_1 Chagasin family peptidase inhibitor I42 K14475 - - 0.00000002488 61.0
SX3_k127_4039930_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 6.625e-267 830.0
SX3_k127_4039930_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.293e-209 659.0
SX3_k127_4039930_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 599.0
SX3_k127_4045840_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 593.0
SX3_k127_4045840_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 516.0
SX3_k127_4045840_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 505.0
SX3_k127_4045840_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 421.0
SX3_k127_4045840_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000003453 246.0
SX3_k127_4045840_5 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000002315 216.0
SX3_k127_4087438_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.059e-299 925.0
SX3_k127_4087438_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006581 247.0
SX3_k127_4087438_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000001669 238.0
SX3_k127_4087438_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000000000000000000003811 145.0
SX3_k127_4120762_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.771e-240 756.0
SX3_k127_4120762_1 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 521.0
SX3_k127_4120762_2 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 398.0
SX3_k127_4120762_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 381.0
SX3_k127_4120762_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 310.0
SX3_k127_4120762_5 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 302.0
SX3_k127_4120762_6 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008712 273.0
SX3_k127_4120762_7 protein conserved in archaea - - - 0.0000000000000000000000000001726 117.0
SX3_k127_4120762_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000000000000000000001712 113.0
SX3_k127_4120762_9 - - - - 0.0000117 50.0
SX3_k127_4133465_0 PFAM amino acid-binding ACT domain protein K06862 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 313.0
SX3_k127_4133465_1 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000003879 233.0
SX3_k127_4133465_2 DNA polymerase beta domain protein region K09717 - - 0.0000000000000000000000000000000000000000000000000000000000002215 214.0
SX3_k127_4133465_3 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000002188 177.0
SX3_k127_4150234_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.046e-314 985.0
SX3_k127_4150234_1 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009584 278.0
SX3_k127_4150234_2 - - - - 0.0000000000000000000000000000009296 123.0
SX3_k127_416066_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 8.584e-194 612.0
SX3_k127_416066_1 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 330.0
SX3_k127_416066_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 321.0
SX3_k127_416066_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000007549 184.0
SX3_k127_4163752_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 594.0
SX3_k127_4163752_1 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000004309 209.0
SX3_k127_4189373_0 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 408.0
SX3_k127_4189373_1 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 310.0
SX3_k127_4189373_2 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001318 241.0
SX3_k127_4189373_3 - - - - 0.0000000000000000000000000000000000000000000000000003851 199.0
SX3_k127_4189373_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.0000000000000000000000000002713 117.0
SX3_k127_4189373_5 PQ loop repeat K15383 - - 0.0000000000000000000008502 97.0
SX3_k127_4206134_0 Belongs to the MCM family K10726 - - 4.395e-303 943.0
SX3_k127_4206134_1 DEAD DEAH box helicase domain protein K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 563.0
SX3_k127_4206134_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 503.0
SX3_k127_4206134_3 PFAM TatD-related deoxyribonuclease K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 380.0
SX3_k127_4206134_4 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 335.0
SX3_k127_4206134_5 pfam nmd3 K07562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 302.0
SX3_k127_4206134_6 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002389 280.0
SX3_k127_4206134_7 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000006444 147.0
SX3_k127_4206134_8 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000000000002754 133.0
SX3_k127_4206134_9 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000000009878 102.0
SX3_k127_421821_0 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000006186 158.0
SX3_k127_4251451_0 in RNase L inhibitor, RLI K06174 - - 4.723e-281 874.0
SX3_k127_4251451_1 Domain of unknown function (DUF814) - - - 6.246e-205 656.0
SX3_k127_4251451_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 401.0
SX3_k127_4251451_3 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 333.0
SX3_k127_4251451_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 316.0
SX3_k127_4251451_5 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001543 232.0
SX3_k127_4251451_6 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000000000000000000000000000000000000000000000000001525 201.0
SX3_k127_4251451_7 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000004313 166.0
SX3_k127_4251451_8 RNase L inhibitor, RLI - - - 0.00000000000000000000000001647 112.0
SX3_k127_4254895_0 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 3.912e-201 633.0
SX3_k127_4254895_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 476.0
SX3_k127_4254895_2 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 369.0
SX3_k127_4267269_0 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 312.0
SX3_k127_4267269_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002675 255.0
SX3_k127_4267269_2 PFAM TPR repeat-containing protein - - - 0.000000000000005817 80.0
SX3_k127_4294637_0 KH, type 1, domain K07041 - - 0.0 1073.0
SX3_k127_4294637_1 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 422.0
SX3_k127_4294637_2 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 385.0
SX3_k127_4294637_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 310.0
SX3_k127_4294637_4 COG0589 Universal stress protein UspA and related nucleotide-binding - - - 0.000000000000000000000000000000000000000000001573 169.0
SX3_k127_4294637_5 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000207 149.0
SX3_k127_4312842_0 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 606.0
SX3_k127_4312842_1 Glycogen debranching enzyme N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 600.0
SX3_k127_4312842_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 537.0
SX3_k127_4312842_3 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 370.0
SX3_k127_4312842_4 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000315 263.0
SX3_k127_4312842_5 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.00000004199 57.0
SX3_k127_4329612_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 2.681e-244 766.0
SX3_k127_4329612_1 Catalase K03781 - 1.11.1.6 3.844e-220 691.0
SX3_k127_4329612_2 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 494.0
SX3_k127_4329612_3 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000000372 146.0
SX3_k127_4329612_4 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 0.0000000000001915 70.0
SX3_k127_434383_0 PFAM Radical SAM domain protein K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 499.0
SX3_k127_434383_1 NAD(P)H-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001273 254.0
SX3_k127_434383_2 Oxidoreductase, short chain dehydrogenase reductase family protein - - - 0.000001957 55.0
SX3_k127_4364084_0 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 312.0
SX3_k127_4364084_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004222 270.0
SX3_k127_4364084_2 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000000000002105 173.0
SX3_k127_4364084_3 - - - - 0.0000000000000000000000000002204 121.0
SX3_k127_4364084_4 Hemerythrin hhe cation binding - - - 0.00003667 52.0
SX3_k127_4385560_0 PFAM amine oxidase - - - 2.197e-194 614.0
SX3_k127_4385560_1 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 372.0
SX3_k127_4385560_2 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 309.0
SX3_k127_4397786_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 574.0
SX3_k127_4397786_1 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 493.0
SX3_k127_4397786_2 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 336.0
SX3_k127_4397786_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000005329 243.0
SX3_k127_4397786_4 PHP C-terminal domain protein - - - 0.0000000000000000000000000000000000000001807 153.0
SX3_k127_4397786_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000005429 93.0
SX3_k127_4405536_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.083e-254 795.0
SX3_k127_4405536_1 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002199 263.0
SX3_k127_4405536_2 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.0000000000000000000004061 97.0
SX3_k127_4405536_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00006179 45.0
SX3_k127_4405833_0 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 434.0
SX3_k127_4405833_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 428.0
SX3_k127_4405833_10 - - - - 0.000000000000003795 85.0
SX3_k127_4405833_11 redox protein regulator of disulfide bond formation - - - 0.0000004489 54.0
SX3_k127_4405833_2 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009834 409.0
SX3_k127_4405833_3 Lon protease (S16) C-terminal proteolytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 296.0
SX3_k127_4405833_4 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000878 259.0
SX3_k127_4405833_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000002327 220.0
SX3_k127_4405833_6 HAD-hyrolase-like K07025 - - 0.00000000000000000000000000000000000000000000000000000000000002345 223.0
SX3_k127_4405833_7 Fe-S-cluster oxidoreductase - - - 0.00000000000000000000000000000000000000000002187 165.0
SX3_k127_4405833_8 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0000000000000000000000000000000000000002116 156.0
SX3_k127_4405833_9 - - - - 0.000000000000000000001808 98.0
SX3_k127_4425581_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000006546 228.0
SX3_k127_4425581_1 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000001375 153.0
SX3_k127_4425581_2 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000000000000000003189 134.0
SX3_k127_4425581_3 SMART Elongator protein 3 MiaB NifB K06936 - - 0.000000000000000000000000000007249 121.0
SX3_k127_4425581_4 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000003439 84.0
SX3_k127_4430285_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 377.0
SX3_k127_4430285_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 332.0
SX3_k127_4430285_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002664 245.0
SX3_k127_4430285_3 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000001591 229.0
SX3_k127_4430285_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000001711 85.0
SX3_k127_4430285_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000009228 80.0
SX3_k127_4435906_0 Belongs to the peptidase S16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 432.0
SX3_k127_4435906_1 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 412.0
SX3_k127_4435906_2 Protein of unknown function (DUF1648) - - - 0.0000000000000000000000000000000000000000000000000000000000002667 220.0
SX3_k127_4439628_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 361.0
SX3_k127_4439628_1 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 349.0
SX3_k127_4439628_10 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.000000000000000000000000000000004838 129.0
SX3_k127_4439628_11 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.000000000000000000000002036 102.0
SX3_k127_4439628_12 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.000000000000000000000008128 105.0
SX3_k127_4439628_13 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000000000000000000009563 104.0
SX3_k127_4439628_14 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000002527 91.0
SX3_k127_4439628_2 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 292.0
SX3_k127_4439628_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000001912 235.0
SX3_k127_4439628_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000004444 218.0
SX3_k127_4439628_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000000000000002264 213.0
SX3_k127_4439628_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000000003234 204.0
SX3_k127_4439628_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000009912 203.0
SX3_k127_4439628_8 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000000000000002531 177.0
SX3_k127_4439628_9 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.0000000000000000000000000000000000000000000607 164.0
SX3_k127_4455792_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 1.708e-234 741.0
SX3_k127_4455792_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 5.925e-229 726.0
SX3_k127_4455792_10 Pfam:DUF552 K09152 - - 0.000000000000000000004164 92.0
SX3_k127_4455792_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.108e-223 706.0
SX3_k127_4455792_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 2.085e-210 666.0
SX3_k127_4455792_4 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 611.0
SX3_k127_4455792_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 471.0
SX3_k127_4455792_6 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 447.0
SX3_k127_4455792_7 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000005535 153.0
SX3_k127_4455792_8 ZPR1-related zinc finger protein K06874 - - 0.00000000000000000000000000000000004675 139.0
SX3_k127_4455792_9 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000001108 150.0
SX3_k127_4477191_0 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 520.0
SX3_k127_4477191_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 519.0
SX3_k127_4477191_2 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 423.0
SX3_k127_4477191_3 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 348.0
SX3_k127_4477191_4 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 295.0
SX3_k127_4477191_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 285.0
SX3_k127_4477191_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000006523 243.0
SX3_k127_4477191_7 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000001771 236.0
SX3_k127_4477191_8 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000001055 182.0
SX3_k127_4478807_0 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 453.0
SX3_k127_4478807_1 Pas domain - - - 0.000000000000000000000000000000000000003548 152.0
SX3_k127_4527526_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.773e-215 677.0
SX3_k127_4527526_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 4.011e-202 638.0
SX3_k127_4527526_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000001871 160.0
SX3_k127_4597419_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 1.058e-217 694.0
SX3_k127_4597419_1 - - - - 0.0000000000000000000000000000000000000000000006162 170.0
SX3_k127_4597419_2 SigmaK-factor processing regulatory protein BofA K06317 - - 0.00000000000000000000004111 101.0
SX3_k127_4597419_3 - - - - 0.000000000000000000009682 91.0
SX3_k127_4597419_4 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000001587 86.0
SX3_k127_4597419_5 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00001248 47.0
SX3_k127_4635115_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.0 1041.0
SX3_k127_4635115_1 N-4 methylation of cytosine K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 361.0
SX3_k127_4635115_2 TPR repeat-containing protein - - - 0.000000000000000000000002991 109.0
SX3_k127_4724386_0 TIGRFAM F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 331.0
SX3_k127_4724386_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 291.0
SX3_k127_4724386_2 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000000000001936 168.0
SX3_k127_4724386_3 Pterin binding enzyme K00796 - 2.5.1.15 0.000000001159 59.0
SX3_k127_4751069_0 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 563.0
SX3_k127_4751069_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 504.0
SX3_k127_4751069_2 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 469.0
SX3_k127_4751069_3 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 355.0
SX3_k127_4751069_4 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000002621 235.0
SX3_k127_4751069_5 PFAM sigma-70 region 4 domain protein K09714 - - 0.0000000000000000000000000000000000000000000000002657 179.0
SX3_k127_4751069_6 Involved in cell shape control K22222 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000003571 177.0
SX3_k127_4774302_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 437.0
SX3_k127_4774302_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 318.0
SX3_k127_4774302_2 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 298.0
SX3_k127_4774302_3 PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003985 278.0
SX3_k127_4774302_4 amino acid K16263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002477 273.0
SX3_k127_4774302_5 small multi-drug export - - - 0.0000000000000000000000000000000000000000000000000000004288 198.0
SX3_k127_4774302_6 PFAM Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000001414 169.0
SX3_k127_4774302_7 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000007119 88.0
SX3_k127_478480_0 TIGRFAM cell division ATPase MinD K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 379.0
SX3_k127_478480_1 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 318.0
SX3_k127_478480_2 Tetratricopeptide repeat - - - 0.00000000000000000001838 99.0
SX3_k127_478480_3 - - - - 0.000006327 51.0
SX3_k127_4785003_0 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 341.0
SX3_k127_4785003_1 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000114 256.0
SX3_k127_4785003_2 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000002283 167.0
SX3_k127_4785003_3 Zinc-ribbon containing domain - - - 0.000000000000000000000000000003315 120.0
SX3_k127_4785003_4 PFAM Desulfoferrodoxin Dfx domain protein - - - 0.000000000000003514 76.0
SX3_k127_4785003_5 Rubrerythrin - - - 0.0000000000003505 70.0
SX3_k127_4828878_0 Predicted membrane protein (DUF2070) K08979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 551.0
SX3_k127_4828878_1 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 371.0
SX3_k127_4828878_2 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000004782 220.0
SX3_k127_4828878_3 Belongs to the UPF0212 family K09731 - - 0.000000000000000000000000000000000000000000000000001291 184.0
SX3_k127_4828878_4 Family of unknown function (DUF5350) - - - 0.00000000000000000000000002236 112.0
SX3_k127_4828878_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.0000000000000003526 80.0
SX3_k127_4867356_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.136e-297 926.0
SX3_k127_4867356_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 584.0
SX3_k127_4867356_10 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007471 266.0
SX3_k127_4867356_11 hydrolase K04794 - 3.1.1.29 0.000000000000000000000000000000000000000000000009828 178.0
SX3_k127_4867356_12 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.00000000000000000000000000000000000000000902 158.0
SX3_k127_4867356_13 - - - - 0.000000000000000000000000000000000000008309 147.0
SX3_k127_4867356_14 PDGLE domain K02009 - - 0.000000000000000000002277 106.0
SX3_k127_4867356_2 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 462.0
SX3_k127_4867356_3 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 439.0
SX3_k127_4867356_4 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 438.0
SX3_k127_4867356_5 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 349.0
SX3_k127_4867356_6 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 316.0
SX3_k127_4867356_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 297.0
SX3_k127_4867356_8 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 297.0
SX3_k127_4867356_9 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001333 265.0
SX3_k127_4937828_0 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 1.048e-300 926.0
SX3_k127_4937828_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 4.5e-282 873.0
SX3_k127_4937828_2 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 316.0
SX3_k127_4937828_3 TIGRFAM cell division ATPase MinD K03609 - - 0.00000000000000000000000000000005919 126.0
SX3_k127_4937828_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000000000000000000000000000002702 123.0
SX3_k127_4937828_5 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000006112 120.0
SX3_k127_4937828_6 - - - - 0.00000000000000001962 90.0
SX3_k127_4937828_7 Roadblock LC7 family protein K06945,K07131 - - 0.0000000000001682 75.0
SX3_k127_4937828_8 - - - - 0.00000005216 61.0
SX3_k127_4938827_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 345.0
SX3_k127_5004400_0 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000002433 218.0
SX3_k127_5004400_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000231 216.0
SX3_k127_5004400_2 Periplasmic copper-binding protein (NosD) - - - 0.0003759 52.0
SX3_k127_5046758_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 3.01e-198 621.0
SX3_k127_5046758_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 334.0
SX3_k127_5067342_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 2.477e-251 778.0
SX3_k127_5067342_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 304.0
SX3_k127_5067342_2 PFAM Glucose-methanol-choline oxidoreductase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 295.0
SX3_k127_5067342_3 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000001256 205.0
SX3_k127_5067342_4 signal transduction protein with CBS domains - - - 0.0000000000000000000000001306 118.0
SX3_k127_5067342_5 CBS domain - - - 0.000000000000003607 86.0
SX3_k127_5069790_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 587.0
SX3_k127_5069790_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000006148 169.0
SX3_k127_5069790_2 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000002641 103.0
SX3_k127_5069790_3 Transcriptional regulator K07108 - - 0.0000000000000000000002121 100.0
SX3_k127_50931_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.024e-245 765.0
SX3_k127_50931_1 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 334.0
SX3_k127_50931_10 PFAM Ribosomal protein K02912 - - 0.000000000000000000000000000000003873 134.0
SX3_k127_50931_2 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000294 258.0
SX3_k127_50931_3 TIGRFAM ribosomal protein L30P K02907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002761 243.0
SX3_k127_50931_4 Integral membrane protein DUF106 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002713 237.0
SX3_k127_50931_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000007533 230.0
SX3_k127_50931_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000000000000000003383 227.0
SX3_k127_50931_7 binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000000000000000000007187 181.0
SX3_k127_50931_8 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000969 163.0
SX3_k127_50931_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000003534 156.0
SX3_k127_5111338_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 4.623e-250 781.0
SX3_k127_5111338_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.064e-233 732.0
SX3_k127_5111338_10 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000001313 208.0
SX3_k127_5111338_11 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000008076 165.0
SX3_k127_5111338_12 light absorption K06893 - - 0.000000000000000000000000000000004024 136.0
SX3_k127_5111338_13 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000004719 101.0
SX3_k127_5111338_14 Phospholipid methyltransferase - - - 0.000000000008609 72.0
SX3_k127_5111338_2 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 477.0
SX3_k127_5111338_3 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 415.0
SX3_k127_5111338_4 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 408.0
SX3_k127_5111338_5 PFAM major facilitator superfamily MFS_1 K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 392.0
SX3_k127_5111338_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 338.0
SX3_k127_5111338_7 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 309.0
SX3_k127_5111338_8 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000005181 240.0
SX3_k127_5111338_9 methyltransferase small K07579 - - 0.00000000000000000000000000000000000000000000000000000000000000000006334 238.0
SX3_k127_5145249_0 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 374.0
SX3_k127_5145249_1 PFAM Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000003617 132.0
SX3_k127_5145249_2 DGC domain protein - - - 0.00000000000000000000000000000233 124.0
SX3_k127_5145249_3 - - - - 0.000000000000000001272 96.0
SX3_k127_5155719_0 PFAM TM2 domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001488 273.0
SX3_k127_5155719_1 PFAM Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005615 259.0
SX3_k127_5155719_2 Radical SAM domain protein - - - 0.000000000000000003656 83.0
SX3_k127_5155719_3 Protein of unknown function (DUF1622) - - - 0.000000000000000008292 85.0
SX3_k127_5176194_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 437.0
SX3_k127_5176194_1 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 294.0
SX3_k127_5176194_2 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000007024 201.0
SX3_k127_5176194_3 COG1202 Superfamily II helicase, archaea-specific - - - 0.00000000000000000000000000000000000000000000000000001795 192.0
SX3_k127_5176194_4 Polysaccharide biosynthesis protein - - - 0.00006065 51.0
SX3_k127_518182_0 PFAM ribonuclease II K01147 - 3.1.13.1 8.107e-201 636.0
SX3_k127_518182_1 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 391.0
SX3_k127_518182_2 PFAM Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000572 251.0
SX3_k127_518182_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000002032 182.0
SX3_k127_518182_4 PFAM Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000479 182.0
SX3_k127_518182_5 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000008816 91.0
SX3_k127_518182_6 Protein of unknown function (DUF2769) - - - 0.000000000000002827 79.0
SX3_k127_518182_7 GYD domain - - - 0.000001612 51.0
SX3_k127_5209068_0 Nitrogenase component 1 type Oxidoreductase K02591 - 1.18.6.1 2.36e-234 732.0
SX3_k127_5209068_1 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 486.0
SX3_k127_5209068_2 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.00000000000000000000000000000000000000000000000000000007016 196.0
SX3_k127_5209068_3 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000000002142 63.0
SX3_k127_5210235_0 PFAM ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 362.0
SX3_k127_5210235_1 COG0863 DNA modification methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
SX3_k127_5210235_2 PFAM SufBD protein K07033 - - 0.0000000000000000000005242 99.0
SX3_k127_5219125_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 574.0
SX3_k127_5219125_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 391.0
SX3_k127_5219125_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 391.0
SX3_k127_5219125_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 313.0
SX3_k127_5219125_4 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000167 253.0
SX3_k127_5219125_5 transcription factor (CBF NF-Y) - - - 0.00000000000000000000000000697 113.0
SX3_k127_5232232_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 582.0
SX3_k127_5232232_1 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 533.0
SX3_k127_5232232_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 445.0
SX3_k127_5232232_3 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 404.0
SX3_k127_5232232_4 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.000000000000000000000000000000000000000000000000003633 184.0
SX3_k127_5260924_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 483.0
SX3_k127_5260924_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 347.0
SX3_k127_5260924_2 - - - - 0.000307 45.0
SX3_k127_5266000_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 587.0
SX3_k127_5266000_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006042 254.0
SX3_k127_5266000_2 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.00000001835 55.0
SX3_k127_5266000_3 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.00004046 47.0
SX3_k127_5293046_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 320.0
SX3_k127_5293046_1 PFAM response regulator receiveR - - - 0.00000000000000000000000000000000000000000000000002034 183.0
SX3_k127_5293046_2 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000000000000000000007632 168.0
SX3_k127_5313601_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 5.857e-278 863.0
SX3_k127_5313601_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 7.552e-228 711.0
SX3_k127_5313601_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 376.0
SX3_k127_5313601_3 PFAM ABC transporter K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002011 251.0
SX3_k127_5313601_4 PFAM ABC transporter related K02068,K03529,K06166,K16786,K16787 - 2.7.8.37 0.000000000000000000000000000000000000000000000000000000000000000000000004662 250.0
SX3_k127_5313601_5 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000000000000000000000000000000000000000001995 203.0
SX3_k127_5313601_6 Radical SAM ThiC family K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000006092 189.0
SX3_k127_5313601_7 PFAM BioY protein K03523 - - 0.000000000000000000000000000000000000000000000000003489 188.0
SX3_k127_5314136_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 9.813e-273 857.0
SX3_k127_5314136_1 SMART Elongator protein 3 MiaB NifB - - - 1.079e-260 816.0
SX3_k127_5314136_10 KH domain protein K06961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005034 249.0
SX3_k127_5314136_11 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000000000000000000000000000000008777 230.0
SX3_k127_5314136_12 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.00000000000000000000000000000000000000000000000000000000000001816 220.0
SX3_k127_5314136_13 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000002063 198.0
SX3_k127_5314136_14 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000000000000000000000001782 141.0
SX3_k127_5314136_15 nucleoside 2-deoxyribosyltransferase - - - 0.0000000000000000000000000000000005425 142.0
SX3_k127_5314136_16 nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000000000002128 110.0
SX3_k127_5314136_17 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000000000002116 93.0
SX3_k127_5314136_18 transcriptional regulators K03724 - - 0.00000000000000000004646 91.0
SX3_k127_5314136_19 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.000000000000000002018 85.0
SX3_k127_5314136_2 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 583.0
SX3_k127_5314136_3 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278 552.0
SX3_k127_5314136_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 504.0
SX3_k127_5314136_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 476.0
SX3_k127_5314136_6 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 456.0
SX3_k127_5314136_7 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 348.0
SX3_k127_5314136_8 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 319.0
SX3_k127_5314136_9 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003642 265.0
SX3_k127_532727_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 388.0
SX3_k127_532727_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000000000000007367 207.0
SX3_k127_532727_3 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000002205 50.0
SX3_k127_5335127_0 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 593.0
SX3_k127_5335127_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 558.0
SX3_k127_5335127_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 436.0
SX3_k127_5335127_3 Belongs to the UPF0285 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 418.0
SX3_k127_5335127_4 Putative small multi-drug export protein - - - 0.0000000000000000000000000000000000000001083 156.0
SX3_k127_5335127_5 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000002372 144.0
SX3_k127_5335127_6 helicase activity K06915 - - 0.000000000000000001638 92.0
SX3_k127_5343076_0 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 4.626e-194 614.0
SX3_k127_5343076_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000001551 152.0
SX3_k127_5389914_0 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 2.262e-210 668.0
SX3_k127_5389914_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.027e-202 637.0
SX3_k127_5389914_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 396.0
SX3_k127_5389914_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 368.0
SX3_k127_5389914_4 FHA domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001242 274.0
SX3_k127_5389914_5 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000213 192.0
SX3_k127_5389914_6 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.000000000000000000000000000000000000009099 150.0
SX3_k127_5414006_0 Ferrous iron transport B domain protein K04759 - - 1.126e-205 657.0
SX3_k127_5414006_1 Helix-hairpin-helix domain K02347 - - 3.499e-202 644.0
SX3_k127_5414006_2 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000032 184.0
SX3_k127_5414006_3 iron dependent repressor K03709,K04758 - - 0.0000000000000000000000000000000002059 139.0
SX3_k127_5414006_4 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.000000000000000000000000000000007978 130.0
SX3_k127_5436900_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 4.6e-210 663.0
SX3_k127_5436900_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 475.0
SX3_k127_5436900_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001543 277.0
SX3_k127_5436900_3 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.00000000000000000000000000000000000000000000000000000000000000000001462 240.0
SX3_k127_5436900_4 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000000000000000000000000000000001199 154.0
SX3_k127_5436900_5 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000000000000000000000000001308 136.0
SX3_k127_5436900_6 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000002098 97.0
SX3_k127_5436900_7 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002579 91.0
SX3_k127_5436900_8 PFAM Ribosomal LX protein K02944 - - 0.0000000000000326 74.0
SX3_k127_5436900_9 Belongs to the PDCD5 family K06875 - - 0.000000001097 59.0
SX3_k127_544145_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 419.0
SX3_k127_544145_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000007625 242.0
SX3_k127_544145_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000004009 217.0
SX3_k127_544145_3 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000003563 210.0
SX3_k127_5470254_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 387.0
SX3_k127_5470254_1 Pas domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001778 279.0
SX3_k127_5470254_2 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001632 259.0
SX3_k127_5470254_3 - - - - 0.000000000000000000000000000000000000000000000000000000008844 213.0
SX3_k127_5489189_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 1.38e-267 835.0
SX3_k127_5489189_1 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00125 - 1.17.1.9 3.029e-217 679.0
SX3_k127_5489189_10 amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000001419 202.0
SX3_k127_5489189_11 - - - - 0.0000000000000000000000000000000000000000000002653 168.0
SX3_k127_5489189_12 - - - - 0.0000000000000000000000000001437 121.0
SX3_k127_5489189_13 - - - - 0.0000000000000000000000002383 108.0
SX3_k127_5489189_14 - - - - 0.000000000000000003495 89.0
SX3_k127_5489189_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 568.0
SX3_k127_5489189_3 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 547.0
SX3_k127_5489189_4 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 431.0
SX3_k127_5489189_5 methanogenesis marker protein 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 407.0
SX3_k127_5489189_6 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 337.0
SX3_k127_5489189_7 MviN-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 338.0
SX3_k127_5489189_8 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 308.0
SX3_k127_5489189_9 cytidyltransferase-related domain K00952 - 2.7.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001309 274.0
SX3_k127_5510350_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 6.063e-194 616.0
SX3_k127_5510350_1 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 616.0
SX3_k127_5510350_2 COG1246 N-acetylglutamate synthase and related acetyltransferases K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000257 223.0
SX3_k127_5510350_3 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000009863 223.0
SX3_k127_5510350_4 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000000000000000001144 112.0
SX3_k127_5510350_5 Sulfide dehydrogenase (Flavoprotein) subunit SudB K00528,K02823 - 1.18.1.2,1.19.1.1 0.00000000136 59.0
SX3_k127_5510350_7 PFAM Amidohydrolase 2 K07045 - - 0.00001184 51.0
SX3_k127_552133_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1161.0
SX3_k127_552133_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.259e-215 674.0
SX3_k127_552133_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 408.0
SX3_k127_552133_3 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000002211 258.0
SX3_k127_552133_4 chromosome segregation and condensation protein ScpA K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002963 253.0
SX3_k127_552133_5 - - - - 0.0000000000000001041 86.0
SX3_k127_5530887_0 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 571.0
SX3_k127_5530887_1 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 412.0
SX3_k127_5530887_2 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 337.0
SX3_k127_5530887_3 Protein phosphatase 2C - - - 0.000000000000000000000000000000000000000000000000000000000000000000007449 245.0
SX3_k127_5530887_4 PFAM Protein kinase domain - - - 0.000000000000000000000000000000000000000000000001656 193.0
SX3_k127_5530887_5 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000115 81.0
SX3_k127_5537382_0 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 342.0
SX3_k127_5537382_1 COG1668 ABC-type Na efflux pump, permease component - - - 0.0000000000000000000000000000000000000000000000000000000002471 213.0
SX3_k127_5572552_0 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 307.0
SX3_k127_5572552_1 ATPases associated with a variety of cellular activities K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 306.0
SX3_k127_5572552_2 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000586 225.0
SX3_k127_5572552_3 Zinc-uptake complex component A periplasmic K02077,K09815 - - 0.000000000000000000000000000000000000000000000000000000000000001397 228.0
SX3_k127_5572552_4 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000000005803 211.0
SX3_k127_5572552_5 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000002312 177.0
SX3_k127_5572552_6 Integral membrane protein DUF106 - - - 0.0000000003204 60.0
SX3_k127_5594939_0 PFAM ABC transporter K00400 - - 1.916e-282 874.0
SX3_k127_5594939_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 8.198e-218 680.0
SX3_k127_5594939_10 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.000000000000000000000000000000000000000000000000000001633 196.0
SX3_k127_5594939_11 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.0000000000000000000000000000000000000000000000000302 183.0
SX3_k127_5594939_2 Glycosyl hydrolase family 57 K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 536.0
SX3_k127_5594939_3 Belongs to the UPF0288 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 539.0
SX3_k127_5594939_4 methanogenesis marker protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 452.0
SX3_k127_5594939_5 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 409.0
SX3_k127_5594939_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 353.0
SX3_k127_5594939_7 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 325.0
SX3_k127_5594939_8 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000105 235.0
SX3_k127_5594939_9 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.00000000000000000000000000000000000000000000000000000009674 200.0
SX3_k127_566866_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 588.0
SX3_k127_566866_1 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 524.0
SX3_k127_5669743_0 LOR SDH bifunctional enzyme conserved - - - 1.171e-197 623.0
SX3_k127_5669743_1 SMART Elongator protein 3 MiaB NifB K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 354.0
SX3_k127_5669743_2 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 310.0
SX3_k127_5669743_3 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.00000000000000000000000000000000000000000000000000007058 192.0
SX3_k127_5757935_0 PFAM TM2 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005125 260.0
SX3_k127_5757935_1 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000006257 222.0
SX3_k127_5757935_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000006094 110.0
SX3_k127_57610_0 E1-E2 ATPase K17686 - 3.6.3.54 9.608e-257 807.0
SX3_k127_57610_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 556.0
SX3_k127_57610_2 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000001031 155.0
SX3_k127_5793201_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 9.964e-299 922.0
SX3_k127_5793201_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 4.446e-235 735.0
SX3_k127_5793201_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 1.732e-231 725.0
SX3_k127_5793201_3 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 9.594e-212 668.0
SX3_k127_5793201_4 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000003392 255.0
SX3_k127_5793201_5 Protein of unknown function (DUF4013) - - - 0.00000000000000000000000000000000000000000000000000000088 199.0
SX3_k127_5798040_0 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000000000000000000000000000008307 230.0
SX3_k127_5798040_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000001179 165.0
SX3_k127_5798040_2 - - - - 0.00000000000000000000000000000000006523 140.0
SX3_k127_5798040_3 UPF0056 membrane protein K05595 - - 0.0000000000000000000000000000000003446 136.0
SX3_k127_5798040_4 PBS lyase HEAT-like repeat - - - 0.0000000000000000002006 98.0
SX3_k127_5798040_5 B-block binding subunit of TFIIIC - - - 0.000000000000000004489 84.0
SX3_k127_5803923_0 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 434.0
SX3_k127_5803923_1 Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 377.0
SX3_k127_5803923_2 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 318.0
SX3_k127_5803923_3 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 316.0
SX3_k127_5803923_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000001368 154.0
SX3_k127_5809019_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 420.0
SX3_k127_5809019_1 O-methyltransferase K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 259.0
SX3_k127_5809019_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000006649 228.0
SX3_k127_5809019_3 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000002424 237.0
SX3_k127_5809019_4 - - - - 0.000000000000000000000000000000000000000000000005403 177.0
SX3_k127_5809019_5 transcription activator, effector binding - - - 0.000000000000000000000000000000000000000000007061 169.0
SX3_k127_5809019_6 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000005829 68.0
SX3_k127_5809019_7 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000002665 61.0
SX3_k127_5809019_8 - - - - 0.000000003272 62.0
SX3_k127_5817797_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.724e-310 963.0
SX3_k127_5817797_1 PFAM Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 596.0
SX3_k127_5817797_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit K01546 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 425.0
SX3_k127_5817797_3 K+-transporting ATPase, c chain K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000008281 163.0
SX3_k127_5838162_0 SMART zinc finger, CDGSH-type domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 314.0
SX3_k127_5838162_1 PFAM RDD domain containing protein - - - 0.00000000000000000000000000000000000000000000000001941 183.0
SX3_k127_5838162_2 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000000000000000000001553 110.0
SX3_k127_5838162_3 - - - - 0.00000000172 60.0
SX3_k127_5943971_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1653.0
SX3_k127_5943971_1 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 526.0
SX3_k127_5943971_2 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 320.0
SX3_k127_5943971_3 Protein of unknown function (DUF432) K09149 - - 0.0000000000000000000000000000000000000000000000000000000001647 211.0
SX3_k127_5943971_4 TIGRFAM UbiD family - - - 0.00000000000000000000000000000000000000000002467 162.0
SX3_k127_5943971_5 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000005353 123.0
SX3_k127_5943971_6 - - - - 0.00000000000000000000004419 106.0
SX3_k127_5943971_7 Histidine kinase-like ATPases - - - 0.0000000003169 72.0
SX3_k127_5945193_0 phosphoesterase RecJ domain protein - - - 9.322e-208 656.0
SX3_k127_5945193_1 SMART Elongator protein 3 MiaB NifB - - - 1.587e-200 634.0
SX3_k127_5945193_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007238 274.0
SX3_k127_5948692_0 Conserved region in glutamate synthase - - - 3.664e-289 893.0
SX3_k127_5948692_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 582.0
SX3_k127_5948692_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002911 274.0
SX3_k127_5948692_3 TIR domain - - - 0.0001648 50.0
SX3_k127_5950322_0 TGS domain protein K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 560.0
SX3_k127_5950322_1 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 390.0
SX3_k127_5950322_2 Pyruvate kinase, alpha/beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006325 270.0
SX3_k127_5950322_3 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000000000000007122 197.0
SX3_k127_5950322_4 Transport of potassium into the cell K03549 - - 0.000000000000000000000000000000003358 129.0
SX3_k127_5950322_5 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0000000000000000001019 98.0
SX3_k127_5963471_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 584.0
SX3_k127_5963471_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 565.0
SX3_k127_5963471_10 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002303 265.0
SX3_k127_5963471_11 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002671 259.0
SX3_k127_5963471_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000000000000000000000000000000000007399 175.0
SX3_k127_5963471_13 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000008448 160.0
SX3_k127_5963471_14 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000001223 57.0
SX3_k127_5963471_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 484.0
SX3_k127_5963471_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 472.0
SX3_k127_5963471_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 368.0
SX3_k127_5963471_5 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 364.0
SX3_k127_5963471_6 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 354.0
SX3_k127_5963471_7 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 342.0
SX3_k127_5963471_8 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 321.0
SX3_k127_5963471_9 Oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 284.0
SX3_k127_5965867_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.235e-231 724.0
SX3_k127_5965867_1 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 596.0
SX3_k127_5965867_10 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0000000000000000000000000000000003263 138.0
SX3_k127_5965867_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000000000000000003825 90.0
SX3_k127_5965867_12 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000002704 76.0
SX3_k127_5965867_13 - - - - 0.000000008468 60.0
SX3_k127_5965867_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 557.0
SX3_k127_5965867_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 387.0
SX3_k127_5965867_4 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 347.0
SX3_k127_5965867_5 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 316.0
SX3_k127_5965867_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000001027 215.0
SX3_k127_5965867_7 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.000000000000000000000000000000000000000000000000000001055 199.0
SX3_k127_5965867_8 binds to the 23S rRNA K02921 - - 0.00000000000000000000000000000000000000003045 154.0
SX3_k127_5965867_9 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000000000000000000000002706 143.0
SX3_k127_6004735_0 TIGRFAM TraB family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 478.0
SX3_k127_6004735_1 Belongs to the UPF0284 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 425.0
SX3_k127_6004735_2 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 417.0
SX3_k127_6004735_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 402.0
SX3_k127_6004735_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001502 274.0
SX3_k127_6004735_5 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000001165 237.0
SX3_k127_6004735_6 PFAM Phosphatidylglycerophosphatase A - - - 0.00000000000000000000000000000000000000000000000000000000005445 211.0
SX3_k127_6004735_7 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000005019 163.0
SX3_k127_6011792_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000201 125.0
SX3_k127_6011792_1 - - - - 0.0006466 48.0
SX3_k127_6017210_0 Heat shock 70 kDa protein K04043 - - 5.905e-295 918.0
SX3_k127_6017210_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 4.366e-247 767.0
SX3_k127_6017210_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 260.0
SX3_k127_6017210_11 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001404 252.0
SX3_k127_6017210_12 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001616 253.0
SX3_k127_6017210_13 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004512 234.0
SX3_k127_6017210_14 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000001119 192.0
SX3_k127_6017210_15 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000001972 191.0
SX3_k127_6017210_16 Thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000000000000002336 175.0
SX3_k127_6017210_17 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000006961 175.0
SX3_k127_6017210_18 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000007724 156.0
SX3_k127_6017210_19 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000006471 72.0
SX3_k127_6017210_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 5.161e-199 630.0
SX3_k127_6017210_20 Protein of unknown function (DUF1646) - - - 0.00000003997 59.0
SX3_k127_6017210_21 4Fe-4S binding domain protein - - - 0.0000006982 56.0
SX3_k127_6017210_22 - - - - 0.00000731 51.0
SX3_k127_6017210_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 503.0
SX3_k127_6017210_4 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 410.0
SX3_k127_6017210_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 392.0
SX3_k127_6017210_6 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 377.0
SX3_k127_6017210_7 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 350.0
SX3_k127_6017210_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000534 278.0
SX3_k127_6017210_9 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006341 282.0
SX3_k127_602199_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 561.0
SX3_k127_602199_1 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 375.0
SX3_k127_602199_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 314.0
SX3_k127_605918_0 sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 356.0
SX3_k127_605918_1 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000002622 225.0
SX3_k127_6066115_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 1.874e-219 685.0
SX3_k127_6066115_1 PFAM Beta propeller domain K14475 - - 4.736e-217 692.0
SX3_k127_6066115_2 PFAM Methyltransferase type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 310.0
SX3_k127_6066115_3 membrane K09167 - - 0.00000000000000000000000000000000000000000000000445 179.0
SX3_k127_6101964_0 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 3.989e-293 908.0
SX3_k127_6101964_1 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 5.394e-203 640.0
SX3_k127_6101964_10 - K14093 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001337 241.0
SX3_k127_6101964_11 Predicted membrane protein (DUF2105) K14098 - - 0.0000000000000000000000000000000000000000000000000000000000006091 220.0
SX3_k127_6101964_12 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaF K14097 - - 0.00000000000000000000000000000000000000000000000000003692 190.0
SX3_k127_6101964_13 - - - - 0.000000000000000000000000000001313 123.0
SX3_k127_6101964_14 Predicted membrane protein (DUF2107) K14096 - - 0.000000000000000000001563 99.0
SX3_k127_6101964_15 PFAM NiFe -hydrogenase-3-type complex Eha, EhaM K14104 - - 0.000000000000000000001964 99.0
SX3_k127_6101964_16 Formylmethanofuran dehydrogenase subunit D K00203 - 1.2.7.12 0.0000000000000000003143 93.0
SX3_k127_6101964_17 Predicted membrane protein (DUF2109) K14094 - - 0.000000000000000005225 90.0
SX3_k127_6101964_18 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000002591 76.0
SX3_k127_6101964_19 Involved in protein export. The function of the beta subunit is - GO:0003674,GO:0005085,GO:0005086,GO:0005488,GO:0005515,GO:0008150,GO:0019899,GO:0051020,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000009246 74.0
SX3_k127_6101964_2 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 546.0
SX3_k127_6101964_20 Predicted membrane protein (DUF2108) K14095 - - 0.0000000000005553 73.0
SX3_k127_6101964_21 - K14100 - - 0.000000003482 59.0
SX3_k127_6101964_3 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 531.0
SX3_k127_6101964_4 PFAM Cation K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 522.0
SX3_k127_6101964_5 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 389.0
SX3_k127_6101964_6 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 306.0
SX3_k127_6101964_7 4Fe-4S dicluster domain K11260,K14107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 287.0
SX3_k127_6101964_8 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaH K14099 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 286.0
SX3_k127_6101964_9 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003736 256.0
SX3_k127_6145992_0 COG0464 ATPases of the AAA class K13525 - - 4.305e-274 865.0
SX3_k127_6145992_1 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 406.0
SX3_k127_6145992_2 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002288 256.0
SX3_k127_6145992_3 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000004594 71.0
SX3_k127_6145992_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00001035 48.0
SX3_k127_6153395_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 5.869e-205 657.0
SX3_k127_6153395_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000007358 157.0
SX3_k127_6153395_2 DNA polymerase activity K02319 - 2.7.7.7 0.00000000000000000000005056 107.0
SX3_k127_6153395_3 Rhodanese-like domain K01069 - 3.1.2.6 0.0000000000000000000008676 95.0
SX3_k127_6153395_4 - - - - 0.0000001102 58.0
SX3_k127_6153395_5 - - - - 0.0000001632 53.0
SX3_k127_6245362_0 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 485.0
SX3_k127_6245362_1 TIGRFAM MIP family channel K02440,K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000002289 238.0
SX3_k127_6245362_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000008107 143.0
SX3_k127_6245362_3 UPF0391 membrane protein - - - 0.00000000000002166 73.0
SX3_k127_6245362_4 Domain of unknown function (DUF4382) - - - 0.0000000000002827 76.0
SX3_k127_6245362_5 SigmaK-factor processing regulatory protein BofA K06317 - - 0.000000000003277 71.0
SX3_k127_6245362_6 PFAM Major intrinsic protein K02440 - - 0.00000001011 56.0
SX3_k127_6260546_0 DNA polymerase beta domain protein region K09717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007807 263.0
SX3_k127_6260546_1 CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000000000000000000000000000000000001 245.0
SX3_k127_6260546_2 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000000000000002159 146.0
SX3_k127_626950_0 acid binding OB-fold tRNA helicase-type K07463 - - 1.191e-240 753.0
SX3_k127_626950_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 383.0
SX3_k127_626950_2 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000003095 188.0
SX3_k127_626950_3 - - - - 0.0000000000000000000000000005549 115.0
SX3_k127_626950_4 - - - - 0.0000000000000000007244 91.0
SX3_k127_626950_5 - - - - 0.000000000000000003681 85.0
SX3_k127_6319118_0 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 319.0
SX3_k127_6319118_1 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000886 207.0
SX3_k127_6319118_2 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000001144 206.0
SX3_k127_6319118_3 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000003546 116.0
SX3_k127_6424798_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 4.636e-209 670.0
SX3_k127_6424798_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 450.0
SX3_k127_6470137_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 8.592e-304 941.0
SX3_k127_6502682_0 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 443.0
SX3_k127_6502682_1 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 318.0
SX3_k127_6502682_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 314.0
SX3_k127_6502682_3 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000001541 213.0
SX3_k127_6502682_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000001094 80.0
SX3_k127_6502682_5 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.000000000007118 67.0
SX3_k127_6507669_0 - - - - 0.000000000000000000000000000000000000000000000000000000001328 204.0
SX3_k127_6507669_1 Fibronectin type III domain - - - 0.00000000006195 72.0
SX3_k127_6538072_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.425e-216 681.0
SX3_k127_6538072_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 489.0
SX3_k127_6538072_10 binds to the 23S rRNA K02922 - - 0.00000000000000000000000000009666 115.0
SX3_k127_6538072_11 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000002377 54.0
SX3_k127_6538072_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 331.0
SX3_k127_6538072_3 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002335 269.0
SX3_k127_6538072_4 PFAM PUA domain containing protein K07575 - - 0.0000000000000000000000000000000000000000000000000000000007969 206.0
SX3_k127_6538072_5 Pfam:DUF552 K09152 - - 0.000000000000000000000000000000000000000000000000000003063 193.0
SX3_k127_6538072_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000208 171.0
SX3_k127_6538072_7 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000000003005 167.0
SX3_k127_6538072_8 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000000000000000004442 132.0
SX3_k127_6538072_9 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000005292 134.0
SX3_k127_6546768_0 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 349.0
SX3_k127_6546768_1 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002908 277.0
SX3_k127_6546768_2 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000001993 109.0
SX3_k127_6555483_0 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 516.0
SX3_k127_6555483_1 aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 395.0
SX3_k127_6555483_2 PFAM extracellular solute-binding protein family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000005508 207.0
SX3_k127_6555483_3 Phage integrase family - - - 0.0006591 45.0
SX3_k127_6576793_0 Rhodanese-like domain K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 497.0
SX3_k127_6576793_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 434.0
SX3_k127_6576793_2 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 422.0
SX3_k127_6576793_3 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 416.0
SX3_k127_6576793_4 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 419.0
SX3_k127_6576793_5 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 306.0
SX3_k127_6576793_6 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 303.0
SX3_k127_658084_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000007819 263.0
SX3_k127_658084_1 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009973 249.0
SX3_k127_658084_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000005946 240.0
SX3_k127_658084_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000000000000000000000000000000000000000000000000000000000003333 214.0
SX3_k127_658084_4 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000006949 186.0
SX3_k127_6620827_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 333.0
SX3_k127_6620827_1 ABC-type tungstate transport system, periplasmic component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001874 279.0
SX3_k127_6620827_2 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008205 268.0
SX3_k127_6707114_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.302e-316 975.0
SX3_k127_6707114_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.453e-268 831.0
SX3_k127_6707114_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 411.0
SX3_k127_6707114_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001102 257.0
SX3_k127_6707114_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000000000000000000000000000004671 198.0
SX3_k127_6707114_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000001398 100.0
SX3_k127_672134_0 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 572.0
SX3_k127_672134_1 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000003259 165.0
SX3_k127_672134_2 protein N-acetylglucosaminyltransferase activity K12600 - - 0.0000000000000000000000000000000005046 142.0
SX3_k127_672134_3 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000003873 134.0
SX3_k127_672134_4 TIGRFAM C_GCAxxG_C_C family - - - 0.0000000000000000000002443 102.0
SX3_k127_672134_5 sister chromatid segregation - - - 0.00004094 54.0
SX3_k127_6734532_0 Predicted membrane protein (DUF2070) K08979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 462.0
SX3_k127_6734532_1 SMART Tetratricopeptide domain protein - - - 0.000000001237 65.0
SX3_k127_679264_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 8.881e-219 689.0
SX3_k127_679264_1 Ferritin-like domain K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000000000000007944 223.0
SX3_k127_679264_2 - - - - 0.000000000000000000000000000000000000000000004017 169.0
SX3_k127_679264_3 Stage II sporulation protein M K06384 - - 0.00000000000000000000000000000000000000002258 159.0
SX3_k127_679264_4 Membrane protein of unknown function DUF63 - - - 0.00000000000007646 72.0
SX3_k127_679264_5 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000004474 59.0
SX3_k127_680367_0 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 429.0
SX3_k127_680367_1 Involved in cell shape control K22222 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000001168 249.0
SX3_k127_680367_2 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000005483 181.0
SX3_k127_695480_0 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 5.894e-222 698.0
SX3_k127_695480_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 529.0
SX3_k127_695480_2 Membrane protein of unknown function DUF63 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 301.0
SX3_k127_695480_3 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001673 273.0
SX3_k127_695480_4 Belongs to the UPF0179 family K09730 - - 0.000000000000000000000000000000000000000000000000000000000969 205.0
SX3_k127_695480_5 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000000000000000006803 172.0
SX3_k127_695480_6 metal-binding protein - - - 0.0000000000000000000000003239 107.0
SX3_k127_697677_0 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000005974 218.0
SX3_k127_697677_1 Belongs to the UPF0305 family - - - 0.00000000000000000000000000000000000000000000001277 176.0
SX3_k127_697677_2 TIGRFAM TraB family protein - - - 0.0000000000000000000000000000000005465 132.0
SX3_k127_807625_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 586.0
SX3_k127_807625_1 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 359.0
SX3_k127_807625_2 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 344.0
SX3_k127_807625_3 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000009206 165.0
SX3_k127_807625_4 B-block binding subunit of TFIIIC - - - 0.000000000000000000000000000000006364 130.0
SX3_k127_807625_5 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000000000001459 125.0
SX3_k127_841157_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1305.0
SX3_k127_841157_1 PFAM PilT protein domain protein K06865 - - 2.133e-279 870.0
SX3_k127_841157_10 - - - - 0.000000000000000000000000000000000000000000905 164.0
SX3_k127_841157_11 Protein of unknown function (DUF473) K09135 - - 0.0000000000000000000000000000000001554 137.0
SX3_k127_841157_12 - - - - 0.0000000000000000000000003371 108.0
SX3_k127_841157_13 - - - - 0.000000000757 68.0
SX3_k127_841157_2 PFAM type II secretion system protein E K07332 - - 9.578e-266 839.0
SX3_k127_841157_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.161e-200 632.0
SX3_k127_841157_4 TIGRFAM cell division ATPase MinD K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 385.0
SX3_k127_841157_5 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 345.0
SX3_k127_841157_6 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 331.0
SX3_k127_841157_7 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000007837 188.0
SX3_k127_841157_8 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000021 178.0
SX3_k127_841157_9 Roadblock LC7 K07131 - - 0.000000000000000000000000000000000000000000001247 167.0
SX3_k127_847174_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 405.0
SX3_k127_847174_1 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000000000002716 229.0
SX3_k127_847174_2 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000003106 146.0
SX3_k127_847174_3 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.0000000000000000001272 92.0
SX3_k127_864471_0 PFAM Radical SAM domain protein K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 569.0
SX3_k127_864471_1 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 0.000000000000000000000000000001757 120.0
SX3_k127_864471_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0007318 42.0
SX3_k127_890770_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.747e-271 842.0
SX3_k127_890770_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 348.0
SX3_k127_890770_2 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 342.0
SX3_k127_890770_3 Belongs to the dCTP deaminase family K01494,K09887 - 3.5.4.13,3.5.4.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 300.0
SX3_k127_890770_4 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000003642 186.0
SX3_k127_890984_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 336.0
SX3_k127_890984_1 Cache_2 - - - 0.000000000000000000000000000000000000000000000009698 175.0
SX3_k127_890984_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.000000000000000000000000000001577 125.0
SX3_k127_918986_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 518.0
SX3_k127_918986_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003416 253.0
SX3_k127_918986_2 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000003191 171.0
SX3_k127_918986_3 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000001968 158.0
SX3_k127_950936_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 1.609e-310 965.0
SX3_k127_950936_1 DEAD DEAH box helicase domain protein K03725 - - 7.1e-283 884.0
SX3_k127_950936_10 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000000000000000000000000000002354 234.0
SX3_k127_950936_11 ArsR transcriptional regulator - - - 0.000000000000000000000000000000000000000003251 160.0
SX3_k127_950936_12 - - - - 0.0000000000000002588 81.0
SX3_k127_950936_2 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.185e-236 739.0
SX3_k127_950936_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 557.0
SX3_k127_950936_4 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 394.0
SX3_k127_950936_5 SMART regulatory protein, Crp K07730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 385.0
SX3_k127_950936_6 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 290.0
SX3_k127_950936_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006279 284.0
SX3_k127_950936_8 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005778 263.0
SX3_k127_950936_9 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001973 255.0
SX3_k127_981287_0 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 605.0
SX3_k127_981287_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 428.0
SX3_k127_981287_2 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000002469 199.0