Overview

ID MAG03678
Name SX3_bin.8
Sample SMP0093
Taxonomy
Kingdom Archaea
Phylum Hydrothermarchaeota
Class Hydrothermarchaeia
Order Hydrothermarchaeales
Family JAZFTJ01
Genus
Species
Assembly information
Completeness (%) 95.81
Contamination (%) 1.34
GC content (%) 58.0
N50 (bp) 13,122
Genome size (bp) 1,410,038

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1369

Gene name Description KEGG GOs EC E-value Score Sequence
SX3_k127_1013083_0 PFAM ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 330.0
SX3_k127_1013083_1 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 325.0
SX3_k127_1013083_2 Predicted permease - - - 0.000000000000000000000005128 116.0
SX3_k127_1013083_5 Transcriptional regulator, PadR-like family - - - 0.0000008634 55.0
SX3_k127_1028_0 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 304.0
SX3_k127_1028_1 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 295.0
SX3_k127_1028_2 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001094 271.0
SX3_k127_1028_3 Protein of unknown function (DUF98) - - - 0.000000000000000000000000000000000000000003114 172.0
SX3_k127_107930_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 466.0
SX3_k127_107930_1 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 418.0
SX3_k127_107930_2 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
SX3_k127_107930_3 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000007754 265.0
SX3_k127_107930_4 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000164 265.0
SX3_k127_107930_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000003451 214.0
SX3_k127_107930_6 Belongs to the UPF0179 family K09730 - - 0.0000000000000000000000001401 111.0
SX3_k127_107930_7 - - - - 0.000000000000000000000009115 110.0
SX3_k127_107930_8 Membrane protein of unknown function DUF63 - - - 0.00000000000000000000004739 108.0
SX3_k127_107930_9 membrane-associated protein domain - - - 0.0000000000000000007834 97.0
SX3_k127_1111271_0 PFAM Integrase core domain - - - 0.00000000000000005215 94.0
SX3_k127_1117255_0 DEAD DEAH box helicase domain protein K10896 - - 3.616e-205 661.0
SX3_k127_1117255_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 608.0
SX3_k127_1117255_10 ERCC4 domain K10896 - - 0.0000000000000000007003 99.0
SX3_k127_1117255_11 Parallel beta-helix repeats - - - 0.00000000000001242 79.0
SX3_k127_1117255_2 Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 607.0
SX3_k127_1117255_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 446.0
SX3_k127_1117255_4 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 440.0
SX3_k127_1117255_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 313.0
SX3_k127_1117255_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002258 263.0
SX3_k127_1117255_7 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000000000000005139 202.0
SX3_k127_1117255_8 Ribbon-helix-helix protein, copG family - - - 0.00000000000000000000000000000000000000000000000001124 187.0
SX3_k127_1117255_9 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 GO:0000041,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006826,GO:0008150,GO:0008152,GO:0008823,GO:0015677,GO:0015682,GO:0016020,GO:0016021,GO:0016491,GO:0016722,GO:0016723,GO:0030001,GO:0031224,GO:0031226,GO:0033216,GO:0034220,GO:0034755,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0052851,GO:0055085,GO:0055114,GO:0071944,GO:0072512,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098706,GO:0098711,GO:0098739,GO:0099587 1.5.1.40 0.0000000000000000000000000000000000000000009126 165.0
SX3_k127_1121777_0 - K07092 - - 0.000000000008638 70.0
SX3_k127_1121777_1 Predicted permease - - - 0.0000000001146 70.0
SX3_k127_1121777_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000002632 52.0
SX3_k127_1129208_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00005329 50.0
SX3_k127_1137490_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000007158 220.0
SX3_k127_1137490_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000723 186.0
SX3_k127_1146746_0 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 372.0
SX3_k127_1146746_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 373.0
SX3_k127_1146746_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000005104 211.0
SX3_k127_1146746_3 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000000000004928 166.0
SX3_k127_1146746_4 COG1078 HD superfamily phosphohydrolases K06885 - - 0.000000000007303 68.0
SX3_k127_1146746_5 Peptidase family M50 - - - 0.000001785 57.0
SX3_k127_1230000_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000001035 205.0
SX3_k127_1230000_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000001572 109.0
SX3_k127_1230000_2 NMT1-like family K02051 - - 0.00000001015 66.0
SX3_k127_1230000_3 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000006732 54.0
SX3_k127_1237511_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000103 201.0
SX3_k127_1239079_0 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 306.0
SX3_k127_1239079_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001739 280.0
SX3_k127_1239079_10 - - - - 0.00000000000001218 79.0
SX3_k127_1239079_11 sister chromatid segregation - - - 0.000042 52.0
SX3_k127_1239079_12 - - - - 0.00026 50.0
SX3_k127_1239079_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000005153 201.0
SX3_k127_1239079_3 Necessary for normal cell division and for the maintenance of normal septation - - - 0.00000000000000000000000000000000000000000000000000002501 193.0
SX3_k127_1239079_4 - - - - 0.000000000000000000000000000000000000000000000001038 186.0
SX3_k127_1239079_5 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000007115 141.0
SX3_k127_1239079_6 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000005125 102.0
SX3_k127_1239079_7 PFAM response regulator receiver K07657,K07658 - - 0.0000000000000000000331 94.0
SX3_k127_1239079_8 - K00960 - 2.7.7.6 0.00000000000000002315 82.0
SX3_k127_1239079_9 E3 Ubiquitin ligase - - - 0.0000000000000001141 89.0
SX3_k127_1335640_0 Belongs to the TCP-1 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.963e-233 734.0
SX3_k127_1335640_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 474.0
SX3_k127_1335640_10 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000001059 194.0
SX3_k127_1335640_11 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000006603 166.0
SX3_k127_1335640_12 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000007022 154.0
SX3_k127_1335640_13 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000002052 126.0
SX3_k127_1335640_14 PFAM phosphatidate cytidylyltransferase - - - 0.000000000000000000000003101 110.0
SX3_k127_1335640_15 Glutaredoxin - - - 0.0000000000000000004806 89.0
SX3_k127_1335640_16 - - - - 0.00000000000000005855 86.0
SX3_k127_1335640_17 - - - - 0.0000002517 62.0
SX3_k127_1335640_18 KIP1-like protein - - - 0.00004571 56.0
SX3_k127_1335640_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 447.0
SX3_k127_1335640_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 381.0
SX3_k127_1335640_4 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 305.0
SX3_k127_1335640_5 ORF6N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 290.0
SX3_k127_1335640_6 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 291.0
SX3_k127_1335640_7 formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001115 281.0
SX3_k127_1335640_8 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003356 286.0
SX3_k127_1335640_9 formylmethanofuran dehydrogenase, subunit C K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000005641 266.0
SX3_k127_1348345_0 formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 8.697e-224 706.0
SX3_k127_1348345_1 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 556.0
SX3_k127_1348345_2 formylmethanofuran dehydrogenase, subunit C K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000001024 240.0
SX3_k127_1348345_3 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000067 212.0
SX3_k127_1348345_4 4Fe-4S dicluster domain K00205 - - 0.00000000000000000000000000000000000000000000000000135 193.0
SX3_k127_1348345_5 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000833 147.0
SX3_k127_1348345_6 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.000000000000000000000000000000771 126.0
SX3_k127_1348345_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11260,K14107 - - 0.00000000000007856 80.0
SX3_k127_1348345_8 Predicted membrane protein (DUF2101) - - - 0.000000000379 63.0
SX3_k127_1425655_0 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000007348 231.0
SX3_k127_1425655_1 PFAM regulatory protein, ArsR - - - 0.0000000000000000000000000000000000000005453 154.0
SX3_k127_1425655_2 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000008313 132.0
SX3_k127_1425655_3 - - - - 0.0000001167 61.0
SX3_k127_1425655_4 PKD domain containing protein K01183 - 3.2.1.14 0.00001216 57.0
SX3_k127_1425655_5 - - - - 0.0000147 54.0
SX3_k127_1483858_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 0.0006651 42.0
SX3_k127_1486122_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.27e-215 679.0
SX3_k127_1486122_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 601.0
SX3_k127_1486122_10 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000001419 177.0
SX3_k127_1486122_11 - - - - 0.000000000000000000000004324 106.0
SX3_k127_1486122_12 Starch synthase catalytic domain K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.0000000000004148 82.0
SX3_k127_1486122_13 Protein of unknown function DUF47 K07220 - - 0.00000002053 63.0
SX3_k127_1486122_2 Quinolinate phosphoribosyl transferase, N-terminal domain K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 458.0
SX3_k127_1486122_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 448.0
SX3_k127_1486122_4 PFAM glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 425.0
SX3_k127_1486122_5 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 395.0
SX3_k127_1486122_6 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 366.0
SX3_k127_1486122_7 PFAM Sugar isomerase (SIS) K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 319.0
SX3_k127_1486122_8 Peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000002201 198.0
SX3_k127_1486122_9 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000025 184.0
SX3_k127_1489761_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000002977 231.0
SX3_k127_1489761_1 PFAM H transporting two-sector ATPase C subunit K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 - 0.0000000000000000002071 94.0
SX3_k127_1489761_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000001263 64.0
SX3_k127_1509580_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.0000000000000000000000000000000000000000000000000000001729 198.0
SX3_k127_1509580_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000006727 179.0
SX3_k127_1509580_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000000000003837 180.0
SX3_k127_1509580_3 structural constituent of ribosome K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000002372 160.0
SX3_k127_1634494_0 intracellular sequestering of iron ion K13625 GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005767,GO:0005773,GO:0005775,GO:0005776,GO:0005829,GO:0006810,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006887,GO:0006955,GO:0008043,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0012505,GO:0016192,GO:0019725,GO:0030003,GO:0030139,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0032991,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042221,GO:0042582,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044422,GO:0044424,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044754,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0070288,GO:0071682,GO:0097577,GO:0097708,GO:0098771,GO:0099503 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 371.0
SX3_k127_1642_0 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 376.0
SX3_k127_1642_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008257 288.0
SX3_k127_1642_10 Stage II sporulation protein M - - - 0.0003551 50.0
SX3_k127_1642_2 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000002126 243.0
SX3_k127_1642_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000005448 198.0
SX3_k127_1642_4 Thioredoxin-like - - - 0.000000000000000000000000000000000000002011 165.0
SX3_k127_1642_5 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000046 158.0
SX3_k127_1642_6 zinc metalloprotease whose natural substrate is K06974 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000005366 151.0
SX3_k127_1642_7 Acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000006505 131.0
SX3_k127_1642_8 PFAM Uncharacterised protein family UPF0058 - - - 0.00000000000000000001405 94.0
SX3_k127_1642_9 Belongs to the UPF0146 family K09713 - - 0.00000000004947 66.0
SX3_k127_167155_0 KaiC - - - 0.00000000000000000000000000000000000000000000000000004659 195.0
SX3_k127_1688943_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 604.0
SX3_k127_1688943_1 HMGL-like K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 565.0
SX3_k127_1688943_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 502.0
SX3_k127_1688943_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001772 284.0
SX3_k127_1688943_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704,K16793 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.114,4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000002861 232.0
SX3_k127_1688943_5 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000001942 234.0
SX3_k127_1688943_6 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000002111 175.0
SX3_k127_1688943_7 domain protein - - - 0.000000000001821 80.0
SX3_k127_1688943_8 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000004474 59.0
SX3_k127_1697940_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 371.0
SX3_k127_1697940_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 343.0
SX3_k127_1697940_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 291.0
SX3_k127_1697940_3 Cytidylyltransferase K19712 - 2.7.7.62 0.0000000000000000000000000000000000000000008473 165.0
SX3_k127_1697940_4 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000003997 162.0
SX3_k127_1697940_5 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000002137 121.0
SX3_k127_1697940_6 - - - - 0.000000000000000000000001573 107.0
SX3_k127_1697940_7 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000009921 78.0
SX3_k127_1736949_0 Transposase, Mutator family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 440.0
SX3_k127_1746376_0 HELICc2 K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000007433 192.0
SX3_k127_1746376_1 Domain of unknown function - - - 0.000000000002566 81.0
SX3_k127_1746376_2 - - - - 0.000005418 57.0
SX3_k127_1782738_0 Phage portal protein - - - 0.0000000000000000000000007845 118.0
SX3_k127_1783934_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 400.0
SX3_k127_1783934_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000005415 74.0
SX3_k127_1789843_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 571.0
SX3_k127_1789843_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 493.0
SX3_k127_1789843_2 Belongs to the UPF0282 family K07022 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 349.0
SX3_k127_1789843_3 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 348.0
SX3_k127_1789843_4 t-RNA-binding domain protein K01874,K06878 - 6.1.1.10 0.000000000000000000000000000005083 122.0
SX3_k127_1789843_5 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.000000000000000000004932 102.0
SX3_k127_1861011_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 611.0
SX3_k127_1861011_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 554.0
SX3_k127_1861011_10 OB-fold nucleic acid binding domain K09746 - - 0.0000000000000000000006954 104.0
SX3_k127_1861011_11 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000006562 101.0
SX3_k127_1861011_12 Protein of unknown function (DUF424) K09148 - - 0.0000000000000000002666 90.0
SX3_k127_1861011_2 COG COG0436 Aspartate tyrosine aromatic aminotransferase K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 370.0
SX3_k127_1861011_3 PFAM ExsB family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000002186 241.0
SX3_k127_1861011_4 TIGRFAM Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000007189 216.0
SX3_k127_1861011_5 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000001277 211.0
SX3_k127_1861011_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000833 195.0
SX3_k127_1861011_7 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000002924 188.0
SX3_k127_1861011_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000002518 151.0
SX3_k127_1861011_9 cheY-homologous receiver domain K07668 - - 0.000000000000000000000007054 109.0
SX3_k127_187669_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.2.7.4 1.346e-278 876.0
SX3_k127_187669_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 5.05e-201 649.0
SX3_k127_187669_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008407 381.0
SX3_k127_187669_11 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 351.0
SX3_k127_187669_12 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 349.0
SX3_k127_187669_13 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 335.0
SX3_k127_187669_14 Proton-conducting membrane transporter K22169 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 337.0
SX3_k127_187669_15 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 327.0
SX3_k127_187669_16 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 320.0
SX3_k127_187669_17 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 302.0
SX3_k127_187669_18 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 295.0
SX3_k127_187669_19 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K22174 - 1.1.98.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 308.0
SX3_k127_187669_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl- CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00192,K00193 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 511.0
SX3_k127_187669_20 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 291.0
SX3_k127_187669_21 Phosphopantothenate/pantothenate synthetase K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 284.0
SX3_k127_187669_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001274 274.0
SX3_k127_187669_23 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001203 271.0
SX3_k127_187669_24 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000006929 252.0
SX3_k127_187669_25 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003137 228.0
SX3_k127_187669_26 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K21816 - 1.8.98.3 0.00000000000000000000000000000000000000000000000000000000003234 219.0
SX3_k127_187669_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000001513 190.0
SX3_k127_187669_28 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000005522 180.0
SX3_k127_187669_29 GHMP kinases N terminal domain K06982 - 2.7.1.169 0.000000000000000000000000000000000000000000001088 179.0
SX3_k127_187669_3 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 481.0
SX3_k127_187669_30 Putative Fe-S cluster K11260 - - 0.0000000000000000000000000000000000000006263 154.0
SX3_k127_187669_31 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000005248 153.0
SX3_k127_187669_32 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.0000000000000000000000000001154 126.0
SX3_k127_187669_33 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.00000000000000000000006372 102.0
SX3_k127_187669_34 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000002764 97.0
SX3_k127_187669_35 In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha- aminoadipate (AAA) pathway K06154 - - 0.000000000000001856 82.0
SX3_k127_187669_36 Belongs to the UPF0248 family K09715 - - 0.00000000000001017 76.0
SX3_k127_187669_37 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000007076 78.0
SX3_k127_187669_38 - K00533,K03616 - 1.12.7.2 0.000000003487 59.0
SX3_k127_187669_39 NADH ubiquinone oxidoreductase subunit 6 (chain J) K00339 - 1.6.5.3 0.00000002341 59.0
SX3_k127_187669_4 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 471.0
SX3_k127_187669_40 Belongs to the glycosyl hydrolase 28 family - - - 0.000003141 53.0
SX3_k127_187669_41 - - - - 0.00004269 48.0
SX3_k127_187669_42 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0004679 46.0
SX3_k127_187669_5 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 467.0
SX3_k127_187669_6 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2) K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 458.0
SX3_k127_187669_7 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 452.0
SX3_k127_187669_8 small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 428.0
SX3_k127_187669_9 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 372.0
SX3_k127_1905716_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 306.0
SX3_k127_1905716_1 membrane - - - 0.0000298 57.0
SX3_k127_1905716_2 Predicted membrane protein (DUF2101) - - - 0.00004589 53.0
SX3_k127_1924656_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 316.0
SX3_k127_1924656_1 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000002861 229.0
SX3_k127_1924656_2 Peptidase M50 - - - 0.000000000000000000001273 112.0
SX3_k127_1924656_3 Subtilase family K01183,K01337,K14645 - 3.2.1.14,3.4.21.50 0.000000000000000008446 98.0
SX3_k127_1924656_4 IMP dehydrogenase activity - - - 0.00002056 58.0
SX3_k127_1924903_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 571.0
SX3_k127_1924903_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000005243 184.0
SX3_k127_1924903_2 CBS domain - - - 0.000000000000000000003244 99.0
SX3_k127_1924903_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000009922 68.0
SX3_k127_1944767_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 561.0
SX3_k127_1944767_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000004514 239.0
SX3_k127_1944767_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000009533 64.0
SX3_k127_1944767_3 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.0003797 46.0
SX3_k127_1954106_0 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 496.0
SX3_k127_1954106_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 454.0
SX3_k127_1954106_10 YHS domain - - - 0.000000000009871 72.0
SX3_k127_1954106_11 TOPRIM - - - 0.0000000004461 71.0
SX3_k127_1954106_12 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0001222 55.0
SX3_k127_1954106_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 334.0
SX3_k127_1954106_3 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000001853 200.0
SX3_k127_1954106_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000005325 195.0
SX3_k127_1954106_5 MgtC family - - - 0.000000000000000000000000000000000000000000008722 178.0
SX3_k127_1954106_6 PFAM MazG nucleotide pyrophosphohydrolase domain - - - 0.0000000000000000000000000002138 120.0
SX3_k127_1954106_7 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000004263 100.0
SX3_k127_1954106_8 peptidase U32 - - - 0.000000000001072 79.0
SX3_k127_1954106_9 Belongs to the UPF0235 family K09131 - - 0.000000000008741 69.0
SX3_k127_198549_0 type II secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 578.0
SX3_k127_198549_1 secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 483.0
SX3_k127_198549_10 serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000004473 237.0
SX3_k127_198549_11 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000007658 227.0
SX3_k127_198549_12 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000005776 218.0
SX3_k127_198549_13 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000004481 219.0
SX3_k127_198549_14 MviN-like protein - - - 0.00000000000000000000000000000000000000000000000000004549 203.0
SX3_k127_198549_15 ATP-grasp domain K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000001124 184.0
SX3_k127_198549_16 SMART KH domain protein K06961 - - 0.000000000000000000000000000000000000000000000000889 180.0
SX3_k127_198549_17 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000000000000000000000000000000000004301 175.0
SX3_k127_198549_18 PFAM Peptidase - - - 0.000000000000000000000000000000000000000009788 160.0
SX3_k127_198549_19 Type II secretion system (T2SS), protein F - - - 0.00000000000000000000000000000000000000002274 164.0
SX3_k127_198549_2 NAD-dependent epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 412.0
SX3_k127_198549_20 mRNA decay K07562 - - 0.0000000000000000000000000000000000006207 151.0
SX3_k127_198549_21 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000004189 134.0
SX3_k127_198549_22 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000001863 122.0
SX3_k127_198549_23 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000000000000000000000164 117.0
SX3_k127_198549_24 - - - - 0.0000000000000000001367 103.0
SX3_k127_198549_25 protein conserved in archaea K09743 - - 0.00000000000000001084 89.0
SX3_k127_198549_26 Zn-ribbon containing protein K07163 - - 0.00000000000001639 78.0
SX3_k127_198549_27 Carboxypeptidase regulatory-like domain - - - 0.0000000000004189 82.0
SX3_k127_198549_28 Protein of unknown function (DUF515) - - - 0.0000000000008627 80.0
SX3_k127_198549_29 PRC-barrel domain - - - 0.0000001295 57.0
SX3_k127_198549_3 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 386.0
SX3_k127_198549_30 PFAM Class III signal peptide - - - 0.0001291 46.0
SX3_k127_198549_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 373.0
SX3_k127_198549_5 Pheromone shutdown - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 313.0
SX3_k127_198549_6 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001224 274.0
SX3_k127_198549_7 TIGRFAM riboflavin-specific deaminase C-terminal K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 252.0
SX3_k127_198549_8 GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000001679 239.0
SX3_k127_198549_9 IMG reference gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000005245 250.0
SX3_k127_2015935_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 340.0
SX3_k127_2015935_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000003861 85.0
SX3_k127_2070077_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000001417 236.0
SX3_k127_2119917_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 500.0
SX3_k127_2119917_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 501.0
SX3_k127_2119917_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 389.0
SX3_k127_2119917_3 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 303.0
SX3_k127_2119917_4 PFAM TrkA-N domain K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000001227 235.0
SX3_k127_2119917_5 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000001305 144.0
SX3_k127_2119917_6 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000006694 104.0
SX3_k127_2119917_7 - - - - 0.000000297 59.0
SX3_k127_2171250_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000001184 270.0
SX3_k127_2171250_1 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000008256 79.0
SX3_k127_2171250_2 4Fe-4S dicluster domain - - - 0.0000000000004052 74.0
SX3_k127_2345819_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.651e-265 829.0
SX3_k127_2345819_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.267e-239 746.0
SX3_k127_2345819_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000002543 235.0
SX3_k127_2345819_3 Belongs to the UPF0216 family K09737 - - 0.00000000000000000000000001614 114.0
SX3_k127_2345819_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.000000000000000000001118 97.0
SX3_k127_2345819_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000003161 102.0
SX3_k127_2345819_6 VanZ like family - - - 0.000000000000001044 82.0
SX3_k127_2345819_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000817 83.0
SX3_k127_2345819_8 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000103 69.0
SX3_k127_2533268_0 PFAM DNA polymerase, beta domain protein region K09717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001111 268.0
SX3_k127_2533268_1 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity K00549 - 2.1.1.14 0.00000000000000000000000000000005068 133.0
SX3_k127_2578352_0 peptidase activity, acting on L-amino acid peptides - - - 0.000000000000000000000000000008294 131.0
SX3_k127_2591281_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000529 225.0
SX3_k127_2592313_0 - - - - 0.000004152 55.0
SX3_k127_2594928_0 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 299.0
SX3_k127_2594928_1 nucleotidyltransferase activity K07075 - - 0.000000000000000000000000000000001059 136.0
SX3_k127_2594928_2 Transcriptional regulator, AbrB family K06193 - - 0.0000168 51.0
SX3_k127_2610958_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 341.0
SX3_k127_2610958_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000473 209.0
SX3_k127_2610958_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.00000000000000000000000000000000000000000000002115 171.0
SX3_k127_2617576_0 cheY-homologous receiver domain K07668 - - 0.0000000000000000000000000001983 119.0
SX3_k127_2642684_0 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007957 248.0
SX3_k127_2642684_1 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000001526 220.0
SX3_k127_2642684_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000002844 154.0
SX3_k127_2642684_3 PDGLE domain K02009 - - 0.0000000003012 71.0
SX3_k127_2659080_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 516.0
SX3_k127_2659080_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 434.0
SX3_k127_2659080_10 Protein of unknown function (DUF2769) - - - 0.0000000004737 64.0
SX3_k127_2659080_11 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000002252 56.0
SX3_k127_2659080_12 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000527 53.0
SX3_k127_2659080_2 transcriptional regulator K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 406.0
SX3_k127_2659080_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 316.0
SX3_k127_2659080_4 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000000000000000000001375 221.0
SX3_k127_2659080_5 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000001606 187.0
SX3_k127_2659080_6 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000004433 164.0
SX3_k127_2659080_7 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000009625 113.0
SX3_k127_2659080_8 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000001575 116.0
SX3_k127_2659080_9 Putative DNA-binding domain K03655 - 3.6.4.12 0.0000000000001846 83.0
SX3_k127_2667150_0 Beta-Casp domain K07041 - - 3.614e-249 783.0
SX3_k127_2667150_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.796e-194 613.0
SX3_k127_2667150_10 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001313 220.0
SX3_k127_2667150_11 Peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000001819 218.0
SX3_k127_2667150_12 Domain of unknown function (DUF1724) - - - 0.000000000000000000000000000000000000000000000000000000000003164 217.0
SX3_k127_2667150_13 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000001398 209.0
SX3_k127_2667150_14 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000008802 191.0
SX3_k127_2667150_15 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000002188 180.0
SX3_k127_2667150_16 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000000000000008176 168.0
SX3_k127_2667150_17 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000001033 170.0
SX3_k127_2667150_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K19694 - - 0.0000000000000000000000000000000000001035 151.0
SX3_k127_2667150_19 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000004058 108.0
SX3_k127_2667150_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 434.0
SX3_k127_2667150_20 PUA domain K07565 - - 0.000000000000000001306 92.0
SX3_k127_2667150_21 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000000000000001964 87.0
SX3_k127_2667150_22 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000007225 49.0
SX3_k127_2667150_23 - - - - 0.0001924 46.0
SX3_k127_2667150_3 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 358.0
SX3_k127_2667150_4 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000346 276.0
SX3_k127_2667150_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001346 257.0
SX3_k127_2667150_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000231 242.0
SX3_k127_2667150_7 Nucleotidyltransferase domain K07073 - - 0.0000000000000000000000000000000000000000000000000000000000000001278 228.0
SX3_k127_2667150_8 PFAM UbiA prenyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002999 221.0
SX3_k127_2667150_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000399 214.0
SX3_k127_2673593_0 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 522.0
SX3_k127_2673593_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 400.0
SX3_k127_2673593_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000008757 228.0
SX3_k127_2673593_3 Haloacid dehalogenase-like hydrolase K01101 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000001733 209.0
SX3_k127_2675600_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.096e-299 938.0
SX3_k127_2675600_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.076e-284 888.0
SX3_k127_2675600_10 Involved in cell shape control K22222 - - 0.000000000000000000000000001574 124.0
SX3_k127_2675600_11 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000002181 105.0
SX3_k127_2675600_12 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000000002133 94.0
SX3_k127_2675600_13 Pfam:DUF70 - - - 0.000000000000002031 81.0
SX3_k127_2675600_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 436.0
SX3_k127_2675600_3 Involved in cell shape control K22222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 386.0
SX3_k127_2675600_4 DUF1512 domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001617 279.0
SX3_k127_2675600_5 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000005739 214.0
SX3_k127_2675600_6 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000000000007766 216.0
SX3_k127_2675600_7 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000003655 197.0
SX3_k127_2675600_8 SpoU rRNA Methylase family - - - 0.00000000000000000000000000000000000000000000001201 188.0
SX3_k127_2675600_9 Involved in cell shape control K22222 - - 0.000000000000000000000000000000000000009178 159.0
SX3_k127_2688079_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 440.0
SX3_k127_2688079_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 394.0
SX3_k127_2688079_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 385.0
SX3_k127_2688079_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 382.0
SX3_k127_2688079_4 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000007076 230.0
SX3_k127_2688079_5 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000004511 129.0
SX3_k127_2688079_6 protein conserved in archaea - - - 0.000000000000000000000000003707 113.0
SX3_k127_2688631_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 5.676e-210 655.0
SX3_k127_2689341_0 Protein-export membrane protein SecD K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001034 283.0
SX3_k127_2689341_1 - - - - 0.0000000000000000000000000000000000000000000000756 173.0
SX3_k127_2689341_2 Involved in protein export K03074 - - 0.0000000000000000000000000000000000000000002223 170.0
SX3_k127_2689341_3 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.000000000000000000000000000000009641 137.0
SX3_k127_2689341_4 Protein of unknown function DUF131 - - - 0.00000000004256 66.0
SX3_k127_2689341_5 - - - - 0.0000001956 54.0
SX3_k127_2689341_6 peptidyl-tyrosine sulfation - - - 0.000004973 58.0
SX3_k127_2694666_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 565.0
SX3_k127_2694666_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 603.0
SX3_k127_2694666_10 Segregation and condensation complex subunit ScpB K06024 - - 0.00000000000000000000000000000002449 132.0
SX3_k127_2694666_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000005966 132.0
SX3_k127_2694666_12 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000005813 115.0
SX3_k127_2694666_13 - - - - 0.000000008418 64.0
SX3_k127_2694666_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000002578 57.0
SX3_k127_2694666_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 551.0
SX3_k127_2694666_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 427.0
SX3_k127_2694666_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 398.0
SX3_k127_2694666_5 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 316.0
SX3_k127_2694666_6 TIGRFAM dihydropteroate synthase-related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006345 250.0
SX3_k127_2694666_7 Flavoprotein K18853 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0042558,GO:0042559,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901283,GO:1901285,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:2001115,GO:2001116,GO:2001117,GO:2001118 1.5.99.15 0.0000000000000000000000000000000000000000000000000000000000001879 221.0
SX3_k127_2694666_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000001621 195.0
SX3_k127_2694666_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.000000000000000000000000000000000001045 141.0
SX3_k127_2711380_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 397.0
SX3_k127_2711380_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 362.0
SX3_k127_2711380_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000008267 111.0
SX3_k127_2711380_3 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.000000000004497 70.0
SX3_k127_274343_0 type II secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 466.0
SX3_k127_274343_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 334.0
SX3_k127_274343_10 membrane K06384 - - 0.000000000003117 76.0
SX3_k127_274343_11 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000001192 70.0
SX3_k127_274343_12 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000002599 66.0
SX3_k127_274343_2 Asparagine synthase K07585 - - 0.00000000000000000000000000000000000000000000000000000000000005382 218.0
SX3_k127_274343_3 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000000000006361 199.0
SX3_k127_274343_4 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000007544 184.0
SX3_k127_274343_5 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000008084 166.0
SX3_k127_274343_6 tRNA-ribosyltransferase - - - 0.0000000000000000000000000000004163 134.0
SX3_k127_274343_7 Belongs to the ribosomal protein L31e family K02910 - - 0.00000000000000000000000002834 112.0
SX3_k127_274343_8 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000005605 93.0
SX3_k127_274343_9 rRNA binding K02944 - - 0.000000000000867 70.0
SX3_k127_2790722_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000003989 210.0
SX3_k127_2790722_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.00000000000000000000000002116 122.0
SX3_k127_2790722_3 PAS domain - - - 0.0003061 48.0
SX3_k127_2804777_0 Belongs to the peptidase S16 family K06870 GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000006226 85.0
SX3_k127_2804777_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00001587 55.0
SX3_k127_2804777_2 helix_turn_helix, Lux Regulon K07690 - - 0.00008874 46.0
SX3_k127_282346_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 7.423e-271 859.0
SX3_k127_282346_1 PFAM Circadian clock protein KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 309.0
SX3_k127_282346_11 - - - - 0.00000000000000000000000001382 111.0
SX3_k127_282346_12 - - - - 0.00000000000000000000001742 100.0
SX3_k127_282346_14 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.0000000000000000001933 90.0
SX3_k127_282346_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 293.0
SX3_k127_282346_20 AsnC family - - - 0.00000002423 58.0
SX3_k127_282346_22 Hexapeptide repeat of succinyl-transferase - - - 0.00003934 46.0
SX3_k127_282346_24 thiamine diphosphate biosynthetic process K03154 - - 0.00005305 49.0
SX3_k127_282346_26 - - - - 0.00008775 46.0
SX3_k127_282346_3 PP-loop family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002221 282.0
SX3_k127_282346_4 KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000002201 237.0
SX3_k127_282346_5 Hemerythrin HHE cation binding domain protein K09155 - - 0.00000000000000000000000000000000000000000000000000000002251 199.0
SX3_k127_282346_6 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000001375 178.0
SX3_k127_282346_7 Ribosomal protein S8e K02995 - - 0.0000000000000000000000000000000000001776 145.0
SX3_k127_282346_9 membrane - - - 0.00000000000000000000000000008034 123.0
SX3_k127_2825678_0 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 545.0
SX3_k127_2825678_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 501.0
SX3_k127_2825678_10 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000000000003116 138.0
SX3_k127_2825678_11 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.0000000000000000000000000000000006363 137.0
SX3_k127_2825678_12 binding domain protein - - - 0.00000000000000000000905 99.0
SX3_k127_2825678_13 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000003215 68.0
SX3_k127_2825678_14 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH - - - 0.00000002186 62.0
SX3_k127_2825678_2 Phenylalanyl-tRNA synthetase beta K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 505.0
SX3_k127_2825678_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 476.0
SX3_k127_2825678_4 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 350.0
SX3_k127_2825678_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000002055 247.0
SX3_k127_2825678_6 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000005361 220.0
SX3_k127_2825678_7 ABC-type transport system involved in cytochrome c biogenesis permease component K02194 - - 0.0000000000000000000000000000000000000000002008 167.0
SX3_k127_2825678_8 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000004392 164.0
SX3_k127_2825678_9 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000005066 148.0
SX3_k127_284007_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.279e-241 762.0
SX3_k127_284007_1 Belongs to the RtcB family K14415 - 6.5.1.3 2.441e-210 665.0
SX3_k127_284007_10 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005065 264.0
SX3_k127_284007_11 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000008361 243.0
SX3_k127_284007_12 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000000000004107 133.0
SX3_k127_284007_13 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000005457 139.0
SX3_k127_284007_14 PFAM Peptidase S24 S26A S26B, conserved region K13280 - 3.4.21.89 0.00000000000000002972 92.0
SX3_k127_284007_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 562.0
SX3_k127_284007_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 542.0
SX3_k127_284007_4 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 492.0
SX3_k127_284007_5 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 464.0
SX3_k127_284007_6 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 364.0
SX3_k127_284007_7 PFAM peptidase U62 modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 369.0
SX3_k127_284007_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 325.0
SX3_k127_284007_9 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 323.0
SX3_k127_2845791_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 556.0
SX3_k127_2845791_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 508.0
SX3_k127_2845791_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 398.0
SX3_k127_2845791_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001152 286.0
SX3_k127_2845791_4 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001922 274.0
SX3_k127_2845791_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000469 233.0
SX3_k127_2845791_6 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000004744 191.0
SX3_k127_2845791_7 PQQ-like domain - - - 0.00000000000000000000000002586 124.0
SX3_k127_2845791_8 TIGRFAM Asp-tRNA(Asn) Glu-tRNA(Gln) amidotransferase, subunit C K02435 - 6.3.5.6,6.3.5.7 0.00000001594 59.0
SX3_k127_2934771_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 311.0
SX3_k127_2934771_1 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002709 257.0
SX3_k127_2934771_2 PFAM Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000005487 204.0
SX3_k127_2934771_3 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000008265 167.0
SX3_k127_2934771_4 geranylgeranyl reductase K00311 - 1.5.5.1 0.0000000000000000005672 93.0
SX3_k127_2934771_5 - - - - 0.000000000001561 79.0
SX3_k127_2934771_6 Pfam:DUF552 K09152 - - 0.0000000005178 66.0
SX3_k127_2934771_7 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing K00123 - 1.17.1.9 0.0000003215 55.0
SX3_k127_2963107_0 DNA polymerase K02319 - 2.7.7.7 2.629e-201 653.0
SX3_k127_2963107_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 589.0
SX3_k127_2963107_10 Putative zinc- or iron-chelating domain K06940 - - 0.0000000002685 68.0
SX3_k127_2963107_2 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 441.0
SX3_k127_2963107_3 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 290.0
SX3_k127_2963107_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009668 263.0
SX3_k127_2963107_5 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000002469 234.0
SX3_k127_2963107_6 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000004359 141.0
SX3_k127_2963107_7 CBS domain - - - 0.000000000000000001024 91.0
SX3_k127_2963107_8 PFAM thiamineS protein K03636 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000001073 90.0
SX3_k127_2963107_9 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.0000000000006403 72.0
SX3_k127_3049207_0 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000001923 130.0
SX3_k127_3049207_1 Acetyltransferase (GNAT) domain - - - 0.0000002168 62.0
SX3_k127_3049207_2 Trm112p-like protein K09791 - - 0.0000004239 52.0
SX3_k127_316755_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 433.0
SX3_k127_316755_1 CoA-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000379 201.0
SX3_k127_316755_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000005367 196.0
SX3_k127_316755_3 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000004177 201.0
SX3_k127_316755_4 - - - - 0.0000000001722 64.0
SX3_k127_316755_5 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.0000000003593 64.0
SX3_k127_3229811_0 MacB-like periplasmic core domain K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 259.0
SX3_k127_3229811_1 MacB-like periplasmic core domain K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000004267 249.0
SX3_k127_3229811_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000001032 105.0
SX3_k127_3319219_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.000000000000000000000006756 114.0
SX3_k127_3343354_0 - - - - 0.00000000000006419 75.0
SX3_k127_3379367_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1175.0
SX3_k127_3379367_1 TCP-1/cpn60 chaperonin family K22447 - - 2.267e-214 678.0
SX3_k127_3379367_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 396.0
SX3_k127_3379367_3 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000000000000000000000000000000000000000000005549 244.0
SX3_k127_3379367_4 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000000000002019 213.0
SX3_k127_3379367_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000003222 198.0
SX3_k127_3379367_6 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000004713 142.0
SX3_k127_3379367_7 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000004053 89.0
SX3_k127_3379367_8 DNA polymerase family B K02319 - 2.7.7.7 0.0000009973 51.0
SX3_k127_3381620_0 Putative phage serine protease XkdF - - - 0.0000000000000006539 85.0
SX3_k127_3387365_0 Molybdenum cofactor synthesis domain protein K03750,K07219 - 2.10.1.1 1.02e-213 682.0
SX3_k127_3387365_1 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 523.0
SX3_k127_3387365_2 PFAM Formylmethanofuran tetrahydromethanopterin formyltransferase Ftr K00672 - 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 388.0
SX3_k127_3387365_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 359.0
SX3_k127_3387365_4 Belongs to the carbohydrate kinase PfkB family K21057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704 2.7.1.213 0.000000000000000000000000000148 126.0
SX3_k127_3387365_5 - - - - 0.000002042 52.0
SX3_k127_3412301_0 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000006651 162.0
SX3_k127_3412301_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000009313 153.0
SX3_k127_3412301_2 membrane-associated protein domain - - - 0.0000000003181 67.0
SX3_k127_3443450_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.016e-249 789.0
SX3_k127_3443450_1 Radical SAM K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 433.0
SX3_k127_3443450_10 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000007054 151.0
SX3_k127_3443450_11 Oligosaccharyl transferase, STT3 subunit K07151 - 2.4.99.18 0.000000000000000000000000000000000001568 160.0
SX3_k127_3443450_12 PFAM Sugar isomerase (SIS) K08094 - 5.3.1.27 0.00000000000000002839 82.0
SX3_k127_3443450_13 transcriptional regulatory protein K09714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000001748 81.0
SX3_k127_3443450_14 COG1522 Transcriptional regulators - - - 0.00000000000003135 86.0
SX3_k127_3443450_15 sporulation resulting in formation of a cellular spore K22349 - 1.16.3.3 0.0000000001264 76.0
SX3_k127_3443450_16 - - - - 0.000005505 56.0
SX3_k127_3443450_2 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 387.0
SX3_k127_3443450_3 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 291.0
SX3_k127_3443450_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000958 265.0
SX3_k127_3443450_5 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000002524 251.0
SX3_k127_3443450_6 PFAM periplasmic copper-binding - - - 0.0000000000000000000000000000000000000000000000000000000000007908 242.0
SX3_k127_3443450_7 ABC-type tungstate transport system, periplasmic component K05773 - - 0.00000000000000000000000000000000000000000000000000000000008514 213.0
SX3_k127_3443450_8 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000113 186.0
SX3_k127_3443450_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.00000000000000000000000000000000000000001134 162.0
SX3_k127_3450264_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.905e-260 827.0
SX3_k127_3450264_1 PFAM Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 526.0
SX3_k127_3450264_10 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000000001604 125.0
SX3_k127_3450264_11 Catalyzes the synthesis of activated sulfate K00860,K07028 - 2.7.1.25 0.0000000000000000000000000009445 119.0
SX3_k127_3450264_12 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.0000000000000000000002276 113.0
SX3_k127_3450264_13 response regulator, receiver K02485,K02490,K03413 - - 0.00000000000000006903 85.0
SX3_k127_3450264_14 Histidine kinase-like ATPases - - - 0.0000000000001692 78.0
SX3_k127_3450264_15 Protein of unknown function (DUF515) - - - 0.0000000000006403 72.0
SX3_k127_3450264_16 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000007394 63.0
SX3_k127_3450264_17 ORF D-335-like protein - - - 0.0000004932 51.0
SX3_k127_3450264_18 membrane protein (DUF2078) K08982 - - 0.000003251 53.0
SX3_k127_3450264_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 456.0
SX3_k127_3450264_3 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 423.0
SX3_k127_3450264_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005729 258.0
SX3_k127_3450264_5 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000003981 196.0
SX3_k127_3450264_6 PFAM AsnC family - - - 0.000000000000000000000000000000000000000000000000000232 189.0
SX3_k127_3450264_7 flavin reductase - - - 0.000000000000000000000000000000000000000005084 161.0
SX3_k127_3450264_8 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.00000000000000000000000000000000002374 151.0
SX3_k127_3450264_9 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.0000000000000000000000000000000158 131.0
SX3_k127_3476691_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 486.0
SX3_k127_3476691_1 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 346.0
SX3_k127_3476691_10 H ACA RNA-protein complex K07569 - - 0.00000006877 57.0
SX3_k127_3476691_2 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000002364 256.0
SX3_k127_3476691_3 DNA polymerase alpha chain like domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001275 245.0
SX3_k127_3476691_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000001824 229.0
SX3_k127_3476691_5 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.0000000000000000000000000000005228 133.0
SX3_k127_3476691_6 ligase activity K06914 - 6.3.4.24 0.0000000000000000009074 94.0
SX3_k127_3476691_7 integral membrane protein - - - 0.000000000000001421 89.0
SX3_k127_3476691_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000001792 78.0
SX3_k127_3476691_9 - - - - 0.00000000000004292 75.0
SX3_k127_3485901_0 - - - - 0.0000000002139 70.0
SX3_k127_3485901_1 - - - - 0.000005219 58.0
SX3_k127_3485901_2 - - - - 0.00005494 51.0
SX3_k127_3511253_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one- carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 443.0
SX3_k127_3511253_1 phosphoesterase RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 423.0
SX3_k127_3511253_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000103 78.0
SX3_k127_3511253_11 Phospholipase D Transphosphatidylase K06131,K06132,K06915 - - 0.000003135 57.0
SX3_k127_3511253_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 409.0
SX3_k127_3511253_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 304.0
SX3_k127_3511253_4 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000005861 271.0
SX3_k127_3511253_5 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000001285 243.0
SX3_k127_3511253_6 Cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000001903 237.0
SX3_k127_3511253_7 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000005558 189.0
SX3_k127_3511253_8 cell wall organization - - - 0.0000000000000000000000000000000000000000000004743 182.0
SX3_k127_3511253_9 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000003485 93.0
SX3_k127_3516703_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 469.0
SX3_k127_3516703_1 - - - - 0.0000000000000000002035 103.0
SX3_k127_3516703_2 Belongs to the UPF0146 family K09713 - - 0.00000000000000077 80.0
SX3_k127_3516703_3 MazG nucleotide pyrophosphohydrolase domain - - - 0.0007284 46.0
SX3_k127_3561906_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 306.0
SX3_k127_3561906_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000336 193.0
SX3_k127_3574185_0 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001372 261.0
SX3_k127_3574185_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006092 251.0
SX3_k127_3574185_2 Pas domain s-box - - - 0.000000000000000000000000000000000000000000000000000000000001061 229.0
SX3_k127_3574185_3 Bacterial regulatory protein, Fis family K07714 - - 0.000000000000001753 90.0
SX3_k127_3600164_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 444.0
SX3_k127_3600164_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 362.0
SX3_k127_3600164_2 Imidazole acetol-phosphate transaminase K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001119 286.0
SX3_k127_3600164_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000002666 237.0
SX3_k127_3600164_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000001424 197.0
SX3_k127_3600164_5 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000006979 175.0
SX3_k127_3600164_6 PFAM ATP-binding region, ATPase domain protein K07636,K07652 - 2.7.13.3 0.00000000000000000000000000000000000005494 166.0
SX3_k127_3600164_7 cheY-homologous receiver domain K07668 - - 0.000000000000000000000001903 107.0
SX3_k127_3615993_0 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000002694 211.0
SX3_k127_3615993_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000002387 105.0
SX3_k127_3615993_2 Belongs to the UPF0284 family - - - 0.000005002 50.0
SX3_k127_3666398_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 542.0
SX3_k127_3666398_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 407.0
SX3_k127_3666398_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000105 176.0
SX3_k127_3666398_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000001292 179.0
SX3_k127_3666398_4 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000008893 168.0
SX3_k127_3765702_0 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000003148 170.0
SX3_k127_3781508_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000323 211.0
SX3_k127_3821597_0 - - - - 0.000000003364 65.0
SX3_k127_383737_0 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 469.0
SX3_k127_383737_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 374.0
SX3_k127_383737_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 340.0
SX3_k127_383737_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000001673 179.0
SX3_k127_383737_4 - - - - 0.0000000000000000000000000000000000000004083 169.0
SX3_k127_383737_5 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000006465 131.0
SX3_k127_3857350_0 - - - - 0.00000000000000000000000000000000000000000000000000000000001147 216.0
SX3_k127_3857350_1 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000135 181.0
SX3_k127_3857350_2 PFAM Sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000002905 172.0
SX3_k127_3959364_0 Transposase - - - 0.00001839 57.0
SX3_k127_410615_0 small GTP-binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 424.0
SX3_k127_410615_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002406 242.0
SX3_k127_410615_2 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000000000000000000000000000000008555 194.0
SX3_k127_410615_3 methyltransferase MtaA CmuA family - - - 0.000000000000000000000000000000000000000003513 171.0
SX3_k127_410615_4 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K00548 - 2.1.1.13 0.0000000000000000000000000000000000000004381 153.0
SX3_k127_410615_5 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000004723 104.0
SX3_k127_410615_6 PFAM response regulator receiver K02485,K03413 - - 0.00000000000000000009727 93.0
SX3_k127_410615_7 PFAM Methyltransferase type 11 - - - 0.00000000000819 76.0
SX3_k127_4226040_0 tripeptidyl-peptidase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000004575 256.0
SX3_k127_4226040_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000001827 180.0
SX3_k127_4226040_2 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.00000000000000002303 95.0
SX3_k127_4226040_3 - - - - 0.0000003882 60.0
SX3_k127_4227181_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1169.0
SX3_k127_4227181_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 1.09e-308 960.0
SX3_k127_4227181_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000003924 225.0
SX3_k127_4227181_11 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000001949 218.0
SX3_k127_4227181_12 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000001417 158.0
SX3_k127_4227181_13 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000005067 154.0
SX3_k127_4227181_14 structural constituent of ribosome K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000004595 102.0
SX3_k127_4227181_15 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000001232 73.0
SX3_k127_4227181_16 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000006988 68.0
SX3_k127_4227181_17 extracellular matrix structural constituent - - - 0.000000007461 69.0
SX3_k127_4227181_18 WD-40 repeat - - - 0.00000007647 66.0
SX3_k127_4227181_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 - 2.7.7.6 1.437e-268 840.0
SX3_k127_4227181_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 611.0
SX3_k127_4227181_4 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 566.0
SX3_k127_4227181_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 412.0
SX3_k127_4227181_6 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 346.0
SX3_k127_4227181_7 PFAM SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 291.0
SX3_k127_4227181_8 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000007869 230.0
SX3_k127_4227181_9 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001569 228.0
SX3_k127_4248500_0 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 390.0
SX3_k127_4248500_1 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 311.0
SX3_k127_4248500_10 membrane-associated protein domain - - - 0.0003525 44.0
SX3_k127_4248500_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 303.0
SX3_k127_4248500_3 PFAM ABC transporter K02003,K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002298 270.0
SX3_k127_4248500_4 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004022 276.0
SX3_k127_4248500_5 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000005316 234.0
SX3_k127_4248500_6 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000001173 174.0
SX3_k127_4248500_7 COG1361 S-layer domain - - - 0.000000000000000000000000006546 126.0
SX3_k127_4248500_8 cheY-homologous receiver domain K02485,K03413 - - 0.00000000000000000004055 95.0
SX3_k127_4248500_9 - - - - 0.00000000000005104 86.0
SX3_k127_4261966_0 PFAM Peptidase - - - 0.0000000007337 72.0
SX3_k127_4293075_0 - - - - 0.00000000000000000000000000000000000138 153.0
SX3_k127_431072_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 511.0
SX3_k127_431072_1 shikimate kinase activity K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000005124 250.0
SX3_k127_431072_2 PFAM Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000002164 225.0
SX3_k127_431072_3 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000002599 210.0
SX3_k127_431072_4 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000001771 209.0
SX3_k127_431072_5 Nitroreductase family - - - 0.00000000000000000000000000000000000000001815 156.0
SX3_k127_431072_6 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000001445 157.0
SX3_k127_431072_7 Signal Transduction Histidine Kinase - - - 0.0000000000000000000001597 102.0
SX3_k127_4314207_0 Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position K01271 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.13.9 0.00000000000000000000000000000000000000000000000000000001024 210.0
SX3_k127_4356868_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 623.0
SX3_k127_4356868_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 545.0
SX3_k127_4356868_10 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0005734 46.0
SX3_k127_4356868_2 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 507.0
SX3_k127_4356868_3 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 490.0
SX3_k127_4356868_4 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 346.0
SX3_k127_4356868_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000009676 246.0
SX3_k127_4356868_6 peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.000000000000000000000000001247 114.0
SX3_k127_4356868_7 Fibronectin type III domain - - - 0.0000000000000000000007146 114.0
SX3_k127_4356868_8 Lrp/AsnC ligand binding domain - - - 0.00000000000000000006486 91.0
SX3_k127_4356868_9 Parallel beta-helix repeat K07218 - - 0.0000004267 65.0
SX3_k127_4421905_0 DEAD DEAH box helicase domain protein K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001496 271.0
SX3_k127_4421905_1 Roadblock LC7 family protein K07131 - - 0.0000000108 56.0
SX3_k127_4426279_0 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000000000000000000000000000000000000000000000007492 183.0
SX3_k127_4426279_1 Adenylate cyclase K05873 - 4.6.1.1 0.000000000000000000000000000000002378 136.0
SX3_k127_443123_0 FlgD Ig-like domain K14194,K19668 - 3.2.1.91 0.00000000000000000000000000004515 132.0
SX3_k127_4450842_0 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000006391 190.0
SX3_k127_4450842_1 PFAM response regulator receiver - - - 0.000000000000000001416 93.0
SX3_k127_4450842_2 response regulator - - - 0.000000000000000003213 89.0
SX3_k127_4478902_0 TIGRFAM glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 604.0
SX3_k127_4478902_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 390.0
SX3_k127_4478902_2 Involved in cell shape control K22222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 379.0
SX3_k127_4478902_3 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 345.0
SX3_k127_4478902_4 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 332.0
SX3_k127_4478902_5 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 308.0
SX3_k127_4478902_6 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 299.0
SX3_k127_4478902_7 methylase K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000000000000000000000005167 246.0
SX3_k127_4478902_8 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000003337 243.0
SX3_k127_4478902_9 biological adhesion - - - 0.00001433 58.0
SX3_k127_4489878_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 477.0
SX3_k127_4489878_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000001475 145.0
SX3_k127_449083_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 5.266e-286 903.0
SX3_k127_449083_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 3.412e-276 875.0
SX3_k127_449083_10 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 359.0
SX3_k127_449083_11 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 304.0
SX3_k127_449083_12 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 286.0
SX3_k127_449083_13 Diphthamide K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001136 286.0
SX3_k127_449083_14 PFAM zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000001928 253.0
SX3_k127_449083_15 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000007031 235.0
SX3_k127_449083_16 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002646 244.0
SX3_k127_449083_17 MobA-like NTP transferase domain K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000008107 228.0
SX3_k127_449083_18 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000001415 213.0
SX3_k127_449083_19 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000002186 214.0
SX3_k127_449083_2 Acetolactate synthase, large subunit K01652 - 2.2.1.6 5.581e-219 692.0
SX3_k127_449083_20 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000003287 216.0
SX3_k127_449083_21 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.00000000000000000000000000000000000000000000000000001059 194.0
SX3_k127_449083_22 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000001122 181.0
SX3_k127_449083_23 PFAM ABC transporter related K01990,K16907 - - 0.00000000000000000000000000000000000000000000003233 177.0
SX3_k127_449083_24 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000001372 179.0
SX3_k127_449083_25 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000001029 164.0
SX3_k127_449083_26 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000008737 156.0
SX3_k127_449083_27 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000002059 165.0
SX3_k127_449083_28 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000001264 143.0
SX3_k127_449083_29 CBS domain - - - 0.000000000000000000000000000000659 125.0
SX3_k127_449083_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.171e-208 658.0
SX3_k127_449083_30 cheY-homologous receiver domain K07668 - - 0.0000000000000000000000000004226 118.0
SX3_k127_449083_31 PQQ-like domain - - - 0.0000000000000000000000000004786 128.0
SX3_k127_449083_32 Type IV leader peptidase family K07991 - 3.4.23.52 0.00000000000000000000000001231 123.0
SX3_k127_449083_33 cheY-homologous receiver domain K07668 - - 0.00000000000000000000000002396 112.0
SX3_k127_449083_34 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000002594 108.0
SX3_k127_449083_35 PFAM response regulator receiver - - - 0.0000000000000000000000003952 113.0
SX3_k127_449083_36 toxin-antitoxin pair type II binding - - - 0.00000000000000000000003578 101.0
SX3_k127_449083_37 cheY-homologous receiver domain K07668 - - 0.00000000000000000000003835 107.0
SX3_k127_449083_38 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000000000000000001257 101.0
SX3_k127_449083_39 archaeal coiled-coil protein - - - 0.00000000000000000000134 105.0
SX3_k127_449083_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.804e-207 655.0
SX3_k127_449083_40 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000002687 105.0
SX3_k127_449083_41 Beta-lactamase superfamily domain - - - 0.0000000000000000001249 92.0
SX3_k127_449083_42 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.00000000000000362 76.0
SX3_k127_449083_43 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000006763 77.0
SX3_k127_449083_44 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000003977 76.0
SX3_k127_449083_45 - - - - 0.000000001872 64.0
SX3_k127_449083_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 526.0
SX3_k127_449083_6 PFAM Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 460.0
SX3_k127_449083_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 421.0
SX3_k127_449083_8 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 414.0
SX3_k127_449083_9 TIGRFAM small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 392.0
SX3_k127_4501027_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 520.0
SX3_k127_4501027_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 497.0
SX3_k127_4501027_10 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 313.0
SX3_k127_4501027_11 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 297.0
SX3_k127_4501027_12 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 289.0
SX3_k127_4501027_13 50S ribosomal protein L4 K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 286.0
SX3_k127_4501027_14 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002524 291.0
SX3_k127_4501027_15 Has ATPase and non-specific DNA-binding activities K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003033 291.0
SX3_k127_4501027_16 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005868 256.0
SX3_k127_4501027_17 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000006876 261.0
SX3_k127_4501027_18 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000006081 243.0
SX3_k127_4501027_19 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000001142 248.0
SX3_k127_4501027_2 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 495.0
SX3_k127_4501027_20 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000007107 224.0
SX3_k127_4501027_21 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003444 216.0
SX3_k127_4501027_22 Belongs to the archaeal adenylate kinase family K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000003759 216.0
SX3_k127_4501027_23 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000007556 223.0
SX3_k127_4501027_24 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000119 211.0
SX3_k127_4501027_25 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000007486 199.0
SX3_k127_4501027_26 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000002349 200.0
SX3_k127_4501027_27 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000001538 198.0
SX3_k127_4501027_28 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000003037 179.0
SX3_k127_4501027_29 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000543 177.0
SX3_k127_4501027_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 489.0
SX3_k127_4501027_30 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000219 175.0
SX3_k127_4501027_31 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000007672 170.0
SX3_k127_4501027_32 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000001153 169.0
SX3_k127_4501027_33 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000003139 166.0
SX3_k127_4501027_34 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000005194 166.0
SX3_k127_4501027_35 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000001477 164.0
SX3_k127_4501027_36 TIGRFAM ribosomal protein L30P K02907 - - 0.0000000000000000000000000000000000000000001632 163.0
SX3_k127_4501027_37 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000002181 161.0
SX3_k127_4501027_38 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000007686 155.0
SX3_k127_4501027_39 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000007011 154.0
SX3_k127_4501027_4 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 401.0
SX3_k127_4501027_40 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001354 149.0
SX3_k127_4501027_41 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000007806 152.0
SX3_k127_4501027_42 binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000000002221 151.0
SX3_k127_4501027_43 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000001351 150.0
SX3_k127_4501027_44 Histidine kinase - - - 0.000000000000000000000000000000000002863 154.0
SX3_k127_4501027_45 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001515 131.0
SX3_k127_4501027_46 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000003881 128.0
SX3_k127_4501027_47 binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000008239 125.0
SX3_k127_4501027_48 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000204 104.0
SX3_k127_4501027_49 Integral membrane protein DUF106 - - - 0.00000000000000000000003351 109.0
SX3_k127_4501027_5 PFAM AAA ATPase central domain protein K07392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 395.0
SX3_k127_4501027_50 Belongs to the eukaryotic ribosomal protein eL14 family K02875 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000008889 100.0
SX3_k127_4501027_51 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000001913 99.0
SX3_k127_4501027_52 Belongs to the eukaryotic ribosomal protein eL34 family K02915 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001403 97.0
SX3_k127_4501027_53 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000000000001524 84.0
SX3_k127_4501027_54 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000002646 80.0
SX3_k127_4501027_55 - - - - 0.0000000000000004969 84.0
SX3_k127_4501027_56 PFAM Ribosomal protein K02912 - - 0.0000000000000005506 84.0
SX3_k127_4501027_57 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014,K03055 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000005973 79.0
SX3_k127_4501027_58 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.0000000000002116 70.0
SX3_k127_4501027_59 Stage II sporulation protein M - - - 0.00007343 53.0
SX3_k127_4501027_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 370.0
SX3_k127_4501027_7 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 366.0
SX3_k127_4501027_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 322.0
SX3_k127_4501027_9 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 305.0
SX3_k127_4547963_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000001326 266.0
SX3_k127_4547963_1 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000001634 227.0
SX3_k127_4547963_2 Glycosyl transferase family 4 K01001 - 2.7.8.15 0.0000000000000000000000000000000000000000000000000000001597 205.0
SX3_k127_4547963_3 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000003126 200.0
SX3_k127_4547963_4 Endonuclease V K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000005321 179.0
SX3_k127_4547963_5 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.0000000000000000000000000000000000000000002505 164.0
SX3_k127_4547963_6 - - - - 0.00000001428 62.0
SX3_k127_4803128_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 546.0
SX3_k127_4803128_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 501.0
SX3_k127_4803128_10 Glycosyltransferase 28 domain - - - 0.00000000000000000000000000000000000000005077 162.0
SX3_k127_4803128_11 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000003349 153.0
SX3_k127_4803128_12 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000002057 134.0
SX3_k127_4803128_13 PFAM Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000003381 136.0
SX3_k127_4803128_14 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071236,GO:0140096 - 0.000000000000000000000000003956 119.0
SX3_k127_4803128_15 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.000000000000000000000000005548 113.0
SX3_k127_4803128_16 NifU-like domain - - - 0.00000000000000000000000009562 108.0
SX3_k127_4803128_17 binds to the 23S rRNA K02922 - - 0.0000000000000000000000001856 106.0
SX3_k127_4803128_18 Belongs to the UPF0147 family K09721 - - 0.0000000000000000000002508 98.0
SX3_k127_4803128_19 Signal transducing histidine kinase, homodimeric domain K02487,K06596 - - 0.0000000000000000000003947 101.0
SX3_k127_4803128_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 345.0
SX3_k127_4803128_3 Trypsin K08070,K08372 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 330.0
SX3_k127_4803128_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 296.0
SX3_k127_4803128_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001891 262.0
SX3_k127_4803128_6 PFAM Glycosyl transferase family 4 K01001 - 2.7.8.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001482 259.0
SX3_k127_4803128_7 PFAM amino acid-binding ACT domain protein K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001057 248.0
SX3_k127_4803128_8 Nicotinamide-nucleotide adenylyltransferase K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000000004322 234.0
SX3_k127_4803128_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000004861 212.0
SX3_k127_4810306_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000008095 183.0
SX3_k127_505137_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 428.0
SX3_k127_505137_1 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001111 243.0
SX3_k127_505137_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000005022 162.0
SX3_k127_5071726_0 Glycogen synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 610.0
SX3_k127_5071726_1 Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP K05716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 472.0
SX3_k127_5071726_10 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000008459 191.0
SX3_k127_5071726_11 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000000006212 179.0
SX3_k127_5071726_12 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000008319 163.0
SX3_k127_5071726_13 PFAM plasmid stabilization system K06218 - - 0.0000000000000000000009762 97.0
SX3_k127_5071726_14 Transcriptional regulator - - - 0.00000000000000000001689 93.0
SX3_k127_5071726_15 PFAM PKD domain containing protein - - - 0.0001276 55.0
SX3_k127_5071726_16 - - - - 0.0006514 49.0
SX3_k127_5071726_2 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 466.0
SX3_k127_5071726_3 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 387.0
SX3_k127_5071726_4 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004786 276.0
SX3_k127_5071726_5 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006814 263.0
SX3_k127_5071726_6 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000001647 255.0
SX3_k127_5071726_7 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000008588 258.0
SX3_k127_5071726_8 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000005066 220.0
SX3_k127_5071726_9 - - - - 0.0000000000000000000000000000000000000000000000000000000003052 218.0
SX3_k127_5095002_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000001792 236.0
SX3_k127_5095002_1 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000007851 213.0
SX3_k127_5095002_2 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000009048 205.0
SX3_k127_5095002_3 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000000000000000000000000000000000000001397 168.0
SX3_k127_5095002_4 SMART Nucleotide binding protein, PINc K07060 - - 0.000000000000005091 80.0
SX3_k127_5100069_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.125e-283 890.0
SX3_k127_5100069_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 5.284e-210 660.0
SX3_k127_5100069_10 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000384 181.0
SX3_k127_5100069_11 V-type ATP synthase subunit I K02123 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006885,GO:0007035,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019725,GO:0019829,GO:0019899,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0045851,GO:0046034,GO:0046390,GO:0046483,GO:0046961,GO:0048878,GO:0050801,GO:0051117,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0055086,GO:0065007,GO:0065008,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000002566 186.0
SX3_k127_5100069_12 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000001517 138.0
SX3_k127_5100069_13 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000001032 130.0
SX3_k127_5100069_14 Adenylate cyclase K05873 - 4.6.1.1 0.00000000000000008378 87.0
SX3_k127_5100069_15 CBS domain - - - 0.00000000000009157 77.0
SX3_k127_5100069_16 PFAM UspA domain protein K06149 - - 0.00000000002707 70.0
SX3_k127_5100069_17 - - - - 0.00002238 53.0
SX3_k127_5100069_18 PRC-barrel domain - - - 0.0001352 52.0
SX3_k127_5100069_19 transcriptional K07729 - - 0.0007884 49.0
SX3_k127_5100069_2 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 570.0
SX3_k127_5100069_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 415.0
SX3_k127_5100069_4 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 386.0
SX3_k127_5100069_5 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 375.0
SX3_k127_5100069_6 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 319.0
SX3_k127_5100069_7 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 315.0
SX3_k127_5100069_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001371 275.0
SX3_k127_5100069_9 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009775 256.0
SX3_k127_51185_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000007988 234.0
SX3_k127_5126666_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 387.0
SX3_k127_5126666_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000002569 143.0
SX3_k127_5126666_2 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000002909 145.0
SX3_k127_5130276_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 574.0
SX3_k127_5130276_1 Belongs to the ompA family K20276 - - 0.00000000000000000000000000006795 134.0
SX3_k127_5130276_2 Required for chromosome condensation and partitioning - - - 0.00002017 58.0
SX3_k127_5130276_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0001303 55.0
SX3_k127_5130277_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 531.0
SX3_k127_5258457_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1608.0
SX3_k127_5258457_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1035.0
SX3_k127_5258457_2 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 385.0
SX3_k127_5258457_3 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 376.0
SX3_k127_5258457_4 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002149 249.0
SX3_k127_5258457_5 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000001572 227.0
SX3_k127_5258457_6 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.000000000000000000000000000000000000000000000000001154 198.0
SX3_k127_5258457_7 - - - - 0.0000000000000001724 83.0
SX3_k127_5284045_0 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001795 242.0
SX3_k127_5284045_1 - - - - 0.000000000000000003233 89.0
SX3_k127_5290028_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 376.0
SX3_k127_5301828_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000006096 220.0
SX3_k127_5301828_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000000000786 179.0
SX3_k127_5301828_2 Roadblock/LC7 domain K07131 - - 0.000005297 53.0
SX3_k127_5301828_3 PFAM Class III signal peptide - - - 0.0006373 44.0
SX3_k127_5313597_0 Peptidase M50 - - - 0.000000000000000000001011 112.0
SX3_k127_5317210_0 P-type ATPase K01537 - 3.6.3.8 6.32e-236 765.0
SX3_k127_5317210_1 AIR synthase related protein domain protein K07388 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 459.0
SX3_k127_5317210_2 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 437.0
SX3_k127_5317210_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 357.0
SX3_k127_5317210_4 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000000000000000000000000001011 216.0
SX3_k127_5317210_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000001959 214.0
SX3_k127_5317210_6 Methionine biosynthesis protein MetW - - - 0.000000000000007313 82.0
SX3_k127_5317210_7 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000009046 70.0
SX3_k127_5317210_8 Transglutaminase-like superfamily - - - 0.00000000001259 77.0
SX3_k127_5318705_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 541.0
SX3_k127_5318705_1 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 488.0
SX3_k127_5318705_10 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
SX3_k127_5318705_11 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000085 255.0
SX3_k127_5318705_12 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.00000000000000000000000000000000000000000000000006052 185.0
SX3_k127_5318705_13 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000001585 178.0
SX3_k127_5318705_14 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000008007 121.0
SX3_k127_5318705_15 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000982 104.0
SX3_k127_5318705_16 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000008278 96.0
SX3_k127_5318705_2 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 454.0
SX3_k127_5318705_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 450.0
SX3_k127_5318705_4 hydrogenase expression formation protein K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 394.0
SX3_k127_5318705_5 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 376.0
SX3_k127_5318705_6 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 361.0
SX3_k127_5318705_7 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 346.0
SX3_k127_5318705_8 Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003555 276.0
SX3_k127_5318705_9 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004873 269.0
SX3_k127_5346705_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000008203 186.0
SX3_k127_5346705_1 DEAD H associated K03724 - - 0.00000002817 55.0
SX3_k127_5355164_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000681 217.0
SX3_k127_5355164_1 Desulfoferrodoxin, N-terminal domain K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000004413 185.0
SX3_k127_5367341_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 561.0
SX3_k127_5367341_1 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 408.0
SX3_k127_5367341_10 ATP dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000007228 198.0
SX3_k127_5367341_11 HWE histidine kinase - - - 0.00000000000000000000000000000000001984 156.0
SX3_k127_5367341_12 ATP-grasp domain K06914 - 6.3.4.24 0.00000000000000000000000008977 111.0
SX3_k127_5367341_13 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000000005433 98.0
SX3_k127_5367341_14 Protein of unknown function (DUF447) K09154 - - 0.000000004758 67.0
SX3_k127_5367341_15 - - - - 0.00004191 56.0
SX3_k127_5367341_2 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 GO:0003674,GO:0003824,GO:0016874,GO:0016879,GO:0016881,GO:0052618 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009136 282.0
SX3_k127_5367341_3 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0043743,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001746 281.0
SX3_k127_5367341_4 C D box methylation guide ribonucleoprotein complex aNOP56 subunit K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009805 274.0
SX3_k127_5367341_5 PFAM transferase hexapeptide repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009436 258.0
SX3_k127_5367341_6 Tubulin/FtsZ family, GTPase domain K22222 - - 0.000000000000000000000000000000000000000000000000000000000000004281 234.0
SX3_k127_5367341_7 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.0000000000000000000000000000000000000000000000000000000000000427 227.0
SX3_k127_5367341_8 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000000000000000000765 239.0
SX3_k127_5367341_9 H4MPT-linked C1 transfer pathway protein K07072 - 2.5.1.131 0.000000000000000000000000000000000000000000000000000000000003821 220.0
SX3_k127_540851_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000006599 189.0
SX3_k127_540851_1 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000002298 186.0
SX3_k127_540851_2 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.0001589 49.0
SX3_k127_5426945_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000001607 242.0
SX3_k127_5426945_1 zinc-ribbon domain - - - 0.00000000000000000000002698 112.0
SX3_k127_5426945_2 - - - - 0.000000000008609 72.0
SX3_k127_5426945_3 serine threonine protein kinase - - - 0.000000000103 74.0
SX3_k127_5426945_4 - - - - 0.0008829 52.0
SX3_k127_5494724_0 DsrE/DsrF-like family - - - 0.000000001987 64.0
SX3_k127_5494724_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000002632 52.0
SX3_k127_5494724_2 Predicted permease K07089 - - 0.000005316 56.0
SX3_k127_5514765_0 - - - - 0.0000000000000000000000000000000000000000000000000000002704 196.0
SX3_k127_5514765_1 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000002009 104.0
SX3_k127_5514765_2 membrane protein (DUF2178) - - - 0.000000000000000000006651 96.0
SX3_k127_5514765_3 Methyltransferase domain K06987 - - 0.00000000000005054 79.0
SX3_k127_5514765_4 - - - - 0.0000004889 54.0
SX3_k127_56013_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 381.0
SX3_k127_565384_0 - - - - 0.00000000000000000000000000000000002456 144.0
SX3_k127_565384_1 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000007365 81.0
SX3_k127_575235_0 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 323.0
SX3_k127_575235_1 PFAM Integrase core domain - - - 0.000000000004389 77.0
SX3_k127_5765002_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 1.73e-236 742.0
SX3_k127_5765002_1 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000001886 119.0
SX3_k127_5912977_0 transcriptional K03718 - - 0.000000009533 64.0
SX3_k127_5912977_1 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.00001605 55.0
SX3_k127_5935696_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.516e-231 730.0
SX3_k127_5935696_1 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 532.0
SX3_k127_5935696_10 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.000000000000000000000000004076 116.0
SX3_k127_5935696_11 COG2111 Multisubunit Na H antiporter, MnhB subunit K05566 - - 0.0000000000000000000006325 100.0
SX3_k127_5935696_12 Multisubunit na h antiporter, mnhf subunit K05570 - - 0.00000000000003127 76.0
SX3_k127_5935696_13 Domain of unknown function (DUF4040) - - - 0.0000000000001667 78.0
SX3_k127_5935696_14 - - - - 0.0000008978 54.0
SX3_k127_5935696_15 - - - - 0.000005354 55.0
SX3_k127_5935696_2 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 484.0
SX3_k127_5935696_3 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 454.0
SX3_k127_5935696_4 PFAM NADH Ubiquinone plastoquinone (complex I) K05568,K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 417.0
SX3_k127_5935696_5 PFAM Sulphate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 362.0
SX3_k127_5935696_6 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
SX3_k127_5935696_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000000006669 130.0
SX3_k127_5935696_8 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.00000000000000000000000000001997 122.0
SX3_k127_5935696_9 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000038 122.0
SX3_k127_5935840_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000006502 252.0
SX3_k127_5935840_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000001447 121.0
SX3_k127_5935840_2 - - - - 0.0001348 45.0
SX3_k127_5943262_0 small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 439.0
SX3_k127_5943262_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000000000000000008154 191.0
SX3_k127_5943262_3 cellulase activity - - - 0.0000002813 66.0
SX3_k127_5943262_4 Roadblock LC7 family protein K07131 - - 0.000001696 50.0
SX3_k127_5943262_5 SMART AAA ATPase K06915 - - 0.0006587 55.0
SX3_k127_5947123_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 379.0
SX3_k127_5947123_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000002601 61.0
SX3_k127_5947862_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.00000000000000000000000000000000000000000000000000000000002813 217.0
SX3_k127_5947862_1 PFAM regulatory protein AsnC Lrp family K03718 - - 0.000000000000000000000000000000000005158 141.0
SX3_k127_5947862_2 Putative TM nitroreductase - - - 0.0000000000000000000000004659 106.0
SX3_k127_5947862_3 - - - - 0.000000000000000000003429 98.0
SX3_k127_5947862_4 - - - - 0.0000000002016 73.0
SX3_k127_5949158_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000472 273.0
SX3_k127_5974159_0 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 306.0
SX3_k127_5974159_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001572 268.0
SX3_k127_5974159_2 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000005413 243.0
SX3_k127_5974159_3 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000001493 250.0
SX3_k127_5974159_4 Histidine kinase A domain protein K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000001837 197.0
SX3_k127_5974159_5 Transcriptional regulator, BadM Rrf2 family - - - 0.0000000000000000000000000000000000000000001995 162.0
SX3_k127_5974159_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000001496 78.0
SX3_k127_5974159_7 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000009321 76.0
SX3_k127_5974159_8 Cobalamin biosynthesis protein CbiX - - - 0.000001948 58.0
SX3_k127_5978729_0 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 513.0
SX3_k127_5985515_0 Belongs to the UPF0282 family K07022 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 346.0
SX3_k127_5985515_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000002336 79.0
SX3_k127_6030121_0 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000002563 169.0
SX3_k127_6030121_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000001818 125.0
SX3_k127_6033640_0 Molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 347.0
SX3_k127_6033640_1 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 317.0
SX3_k127_6033640_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008106 241.0
SX3_k127_6033640_3 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000002485 167.0
SX3_k127_6033640_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000009216 131.0
SX3_k127_6033640_5 phosphorelay signal transduction system K07658 - - 0.00000000000000000000005762 112.0
SX3_k127_6033640_6 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000004815 72.0
SX3_k127_6033640_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000741 74.0
SX3_k127_6033640_8 diguanylate cyclase - - - 0.0000000003034 68.0
SX3_k127_6055326_0 - - - - 0.000000000001435 77.0
SX3_k127_6055326_1 recA bacterial DNA recombination protein - - - 0.000000003931 61.0
SX3_k127_60638_0 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 298.0
SX3_k127_60638_1 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000001105 205.0
SX3_k127_60638_2 Putative O-antigen polymerase - - - 0.00000000000000000000000002679 124.0
SX3_k127_60638_3 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000008535 100.0
SX3_k127_60638_4 Archaeal transcriptional regulator TrmB - - - 0.00000000000000002548 91.0
SX3_k127_6105532_0 Pyruvate kinase K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 415.0
SX3_k127_6105532_1 Rubrerythrin K19824 - - 0.00000000000000000000000000000000009561 142.0
SX3_k127_6105532_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000391 67.0
SX3_k127_6106107_0 Cell division protein 48 (CDC48) N-terminal domain K13525 - - 2.938e-302 945.0
SX3_k127_6106107_1 Heat shock 70 kDa protein K04043 - - 6.708e-254 797.0
SX3_k127_6106107_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000008808 142.0
SX3_k127_6106107_11 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000106 136.0
SX3_k127_6106107_12 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000001313 123.0
SX3_k127_6106107_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000004806 119.0
SX3_k127_6106107_14 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.0000000000000000000006426 97.0
SX3_k127_6106107_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000002874 87.0
SX3_k127_6106107_16 Protein of unknown function (DUF1525) - - - 0.000000000000001168 80.0
SX3_k127_6106107_17 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000001141 75.0
SX3_k127_6106107_18 - - - - 0.00000000000002189 78.0
SX3_k127_6106107_19 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000005778 50.0
SX3_k127_6106107_2 Cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 433.0
SX3_k127_6106107_20 Bacterial membrane protein, YfhO - - - 0.00003012 50.0
SX3_k127_6106107_21 MYM-type Zinc finger with FCS sequence motif - - - 0.0009222 42.0
SX3_k127_6106107_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 428.0
SX3_k127_6106107_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 380.0
SX3_k127_6106107_5 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 381.0
SX3_k127_6106107_6 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000006025 240.0
SX3_k127_6106107_7 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000002266 235.0
SX3_k127_6106107_8 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000006914 209.0
SX3_k127_6106107_9 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000003086 199.0
SX3_k127_6113050_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.029e-256 804.0
SX3_k127_6113050_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 489.0
SX3_k127_6113050_10 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000008135 205.0
SX3_k127_6113050_11 ATP-grasp domain K06913 - - 0.00000000000000000000000000000000000000000000000000000003568 211.0
SX3_k127_6113050_12 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000001042 174.0
SX3_k127_6113050_13 TIGRFAM molybdenum cofactor synthesis K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000001179 165.0
SX3_k127_6113050_14 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.0000000000000000000000000000000000000000004793 166.0
SX3_k127_6113050_15 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000009022 160.0
SX3_k127_6113050_16 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000000344 154.0
SX3_k127_6113050_17 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000001807 148.0
SX3_k127_6113050_18 Protein of unknown function (DUF1697) - - - 0.0000000000000000000003934 99.0
SX3_k127_6113050_19 Starch synthase catalytic K16149 - 2.4.1.18 0.000000000000000007789 97.0
SX3_k127_6113050_2 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 452.0
SX3_k127_6113050_20 Rhomboid family K07059 - - 0.000000000001575 72.0
SX3_k127_6113050_21 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000001785 70.0
SX3_k127_6113050_22 Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 - - 0.00000000002973 67.0
SX3_k127_6113050_23 Domain of unknown function (DUF1610) K07580 - - 0.00000000003453 64.0
SX3_k127_6113050_24 Putative zinc- or iron-chelating domain K06940 - - 0.00000002205 63.0
SX3_k127_6113050_25 membrane-bound metal-dependent K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000103 53.0
SX3_k127_6113050_3 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 432.0
SX3_k127_6113050_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 392.0
SX3_k127_6113050_5 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 391.0
SX3_k127_6113050_6 SMART Elongator protein 3 MiaB NifB K06936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005638 273.0
SX3_k127_6113050_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000005163 224.0
SX3_k127_6113050_8 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000001627 214.0
SX3_k127_6113050_9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000001643 219.0
SX3_k127_6125885_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.757e-298 928.0
SX3_k127_6125885_1 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 477.0
SX3_k127_6125885_10 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000009853 236.0
SX3_k127_6125885_11 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000001643 212.0
SX3_k127_6125885_12 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000001628 196.0
SX3_k127_6125885_13 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000001429 198.0
SX3_k127_6125885_14 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000001503 177.0
SX3_k127_6125885_15 - - - - 0.00000000000000000000000000000000000000000004647 173.0
SX3_k127_6125885_16 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000001883 164.0
SX3_k127_6125885_17 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000002052 149.0
SX3_k127_6125885_18 binds to the 23S rRNA K02929 - - 0.000000000000000000000000002637 117.0
SX3_k127_6125885_19 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000001421 101.0
SX3_k127_6125885_2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 467.0
SX3_k127_6125885_20 PAS PAC domain-like protein - - - 0.0000000000000000007366 96.0
SX3_k127_6125885_21 PFAM Ribosomal protein S27E K02978 - - 0.00000000000000001892 83.0
SX3_k127_6125885_22 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000005674 82.0
SX3_k127_6125885_23 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000461 73.0
SX3_k127_6125885_24 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000003078 64.0
SX3_k127_6125885_25 protein conserved in archaea K09723 - - 0.00000000008091 70.0
SX3_k127_6125885_26 KEOPS complex Cgi121-like subunit K09119 - - 0.00000004396 61.0
SX3_k127_6125885_27 Peptidyl-tRNA hydrolase PTH2 K04794 - 3.1.1.29 0.0000006355 52.0
SX3_k127_6125885_3 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 407.0
SX3_k127_6125885_4 PFAM PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 402.0
SX3_k127_6125885_5 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 330.0
SX3_k127_6125885_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 306.0
SX3_k127_6125885_7 ATP cone domain K05715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006073 279.0
SX3_k127_6125885_8 Fumarate hydratase K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001598 271.0
SX3_k127_6125885_9 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003156 269.0
SX3_k127_6136695_0 Transposase DDE domain - - - 0.00000000000000000000000000000000001302 151.0
SX3_k127_6136695_1 ATP-grasp domain K06913 - - 0.00000003119 59.0
SX3_k127_6140948_0 DEAD DEAH box helicase domain protein K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 376.0
SX3_k127_6178137_0 Large family of predicted nucleotide-binding domains K06865 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 583.0
SX3_k127_6178137_1 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000884 160.0
SX3_k127_6178137_2 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.00000000006764 64.0
SX3_k127_6178137_3 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0001881 55.0
SX3_k127_6234480_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002226 278.0
SX3_k127_6234480_1 Pfam:DUF650 - - - 0.0000000000000000000000000000000000000000000000000000000000000001038 224.0
SX3_k127_6234480_2 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000000005992 165.0
SX3_k127_6241038_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 577.0
SX3_k127_6241038_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 527.0
SX3_k127_6241038_10 signal transduction protein with CBS domains - - - 0.000000000000000000001009 100.0
SX3_k127_6241038_11 quorum sensing - - - 0.000000000000000000017 98.0
SX3_k127_6241038_12 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000003643 71.0
SX3_k127_6241038_13 - - - - 0.00000002362 63.0
SX3_k127_6241038_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 336.0
SX3_k127_6241038_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000008671 248.0
SX3_k127_6241038_4 Protein of unknown function (DUF530) K09724 - - 0.0000000000000000000000000000000000000000000000000000000000000001648 242.0
SX3_k127_6241038_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000000000000002492 190.0
SX3_k127_6241038_6 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000000000645 162.0
SX3_k127_6241038_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000004197 141.0
SX3_k127_6241038_8 Domain of unknown function (DUF371) K09738 - - 0.000000000000000000000000000000009313 134.0
SX3_k127_6241038_9 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000003987 100.0
SX3_k127_6251187_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 4.666e-196 615.0
SX3_k127_6251187_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 328.0
SX3_k127_6251187_10 - - - - 0.0000000003465 68.0
SX3_k127_6251187_11 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000006696 52.0
SX3_k127_6251187_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 292.0
SX3_k127_6251187_3 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001301 287.0
SX3_k127_6251187_4 ADP-specific Phosphofructokinase/Glucokinase conserved region K00918 - 2.7.1.146,2.7.1.147 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003691 284.0
SX3_k127_6251187_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001572 265.0
SX3_k127_6251187_6 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000918 265.0
SX3_k127_6251187_7 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000176 225.0
SX3_k127_6251187_8 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000007203 188.0
SX3_k127_6251187_9 Protein of unknown function (DUF531) K09725 - - 0.00000000000000000000000000000000473 140.0
SX3_k127_6269848_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 4.957e-231 732.0
SX3_k127_6269848_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 550.0
SX3_k127_6269848_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 291.0
SX3_k127_6269848_11 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 295.0
SX3_k127_6269848_12 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004236 273.0
SX3_k127_6269848_13 mature ribosome assembly K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007292 255.0
SX3_k127_6269848_14 Protein of unknown function (DUF432) K09149 - - 0.000000000000000000000000000000000000000000000000000001315 200.0
SX3_k127_6269848_15 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000002241 197.0
SX3_k127_6269848_16 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000717 192.0
SX3_k127_6269848_17 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.000000000000000000000000000000000000000000000001999 181.0
SX3_k127_6269848_18 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000001554 178.0
SX3_k127_6269848_19 50S ribosomal protein L37Ae K02921 - - 0.000000000000000000000000009486 111.0
SX3_k127_6269848_2 CorA-like Mg2+ transporter protein K03284 GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 477.0
SX3_k127_6269848_20 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000000764 93.0
SX3_k127_6269848_21 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.0000000000000000724 90.0
SX3_k127_6269848_22 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000006886 79.0
SX3_k127_6269848_23 Transcription factor Pcc1 K09741 - - 0.0000000004472 65.0
SX3_k127_6269848_24 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000004684 57.0
SX3_k127_6269848_25 Sulfite exporter TauE/SafE K07090 - - 0.0000001493 54.0
SX3_k127_6269848_3 PFAM GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 432.0
SX3_k127_6269848_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 424.0
SX3_k127_6269848_5 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 430.0
SX3_k127_6269848_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 358.0
SX3_k127_6269848_7 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009256 347.0
SX3_k127_6269848_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 331.0
SX3_k127_6269848_9 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 325.0
SX3_k127_6299108_0 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002014 291.0
SX3_k127_6299108_1 Tripartite tricarboxylate transporter TctA family K08971 - - 0.000000000000000000000000000000000000000000000000000003026 201.0
SX3_k127_6299108_2 Protein of unknown function (DUF434) - - - 0.0000000000000000000000000000000000000001634 158.0
SX3_k127_6299108_3 TrkA-N domain K03499 - - 0.0000000000000000000000000000003769 129.0
SX3_k127_6299108_4 Nucleic acid binding - - - 0.0000000004956 70.0
SX3_k127_6333706_0 phosphohydrolase K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 297.0
SX3_k127_6417443_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 9.986e-215 683.0
SX3_k127_6417443_1 domain protein K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000025 231.0
SX3_k127_6417443_2 TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - 0.000000000000000002459 93.0
SX3_k127_6502568_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1031.0
SX3_k127_6502568_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000007346 55.0
SX3_k127_6503073_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 464.0
SX3_k127_6503073_1 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000003116 233.0
SX3_k127_6503073_2 Anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000005563 139.0
SX3_k127_6510098_0 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008679 276.0
SX3_k127_6510098_1 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000005162 101.0
SX3_k127_6548992_0 Peptidase M50 - - - 0.000000000926 60.0
SX3_k127_6548992_1 - - - - 0.0005701 51.0
SX3_k127_6581388_0 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000004183 182.0
SX3_k127_6581388_1 LysE type translocator - - - 0.00000000000000000000000000000000000000000000001791 179.0
SX3_k127_6581388_2 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000001986 156.0
SX3_k127_6581388_3 DSBA-like thioredoxin domain - - - 0.00000003045 62.0
SX3_k127_845483_0 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 396.0
SX3_k127_845483_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 388.0
SX3_k127_845483_10 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000001345 168.0
SX3_k127_845483_11 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000638 155.0
SX3_k127_845483_12 - - - - 0.00000000000000000000000000000000007638 136.0
SX3_k127_845483_13 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.000000000000000000000000000000164 126.0
SX3_k127_845483_14 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000001669 115.0
SX3_k127_845483_15 Peptidase S24-like K13280 - 3.4.21.89 0.000000000000000000000001083 109.0
SX3_k127_845483_16 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000000866 87.0
SX3_k127_845483_17 - K00960 - 2.7.7.6 0.00000000000000415 76.0
SX3_k127_845483_18 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000003265 76.0
SX3_k127_845483_19 Ribonuclease III - - - 0.00000000002781 74.0
SX3_k127_845483_2 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 398.0
SX3_k127_845483_20 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000001378 69.0
SX3_k127_845483_21 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.000000004748 63.0
SX3_k127_845483_22 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000005224 55.0
SX3_k127_845483_23 Phosphate uptake regulator, PhoU - - - 0.000005983 58.0
SX3_k127_845483_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 289.0
SX3_k127_845483_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000004811 264.0
SX3_k127_845483_5 RNA polymerase K03049 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000001649 241.0
SX3_k127_845483_6 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000000000000002738 205.0
SX3_k127_845483_7 methyltransferase small K07579 - - 0.0000000000000000000000000000000000000000000000000000008012 204.0
SX3_k127_845483_8 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000000000000000000000001912 185.0
SX3_k127_845483_9 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000002768 187.0
SX3_k127_846_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 444.0
SX3_k127_846_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 425.0
SX3_k127_846_10 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000001848 192.0
SX3_k127_846_11 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000002805 122.0
SX3_k127_846_12 Domain of unknown function (DUF1805) - - - 0.00000000000000000000000005115 109.0
SX3_k127_846_13 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate family K00171 - 1.2.7.1 0.00000000000000000000000006402 109.0
SX3_k127_846_14 cheY-homologous receiver domain K07668 - - 0.000000000000000000000000829 117.0
SX3_k127_846_15 CBS domain - - - 0.000000000000000000000009554 107.0
SX3_k127_846_16 subunit (C K02119 - - 0.0000000000000000000009574 107.0
SX3_k127_846_17 PFAM CBS domain containing protein - - - 0.00000000000000002405 88.0
SX3_k127_846_18 ATP synthase subunit C K02124 - - 0.00000001549 61.0
SX3_k127_846_19 Snare associated golgi protein - - - 0.00000004649 61.0
SX3_k127_846_2 PFAM Thiamine pyrophosphate enzyme, C-terminal K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 406.0
SX3_k127_846_20 Roadblock LC7 family protein K07131 - - 0.0000001197 55.0
SX3_k127_846_21 PFAM regulatory protein, MarR - - - 0.0000004289 61.0
SX3_k127_846_22 PFAM regulatory protein, MarR - - - 0.0000004289 61.0
SX3_k127_846_23 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000009817 54.0
SX3_k127_846_3 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 - 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 317.0
SX3_k127_846_4 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 302.0
SX3_k127_846_5 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 - 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006765 282.0
SX3_k127_846_6 Belongs to the UPF0285 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002796 284.0
SX3_k127_846_7 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001823 271.0
SX3_k127_846_8 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000008209 231.0
SX3_k127_846_9 V-type ATPase 116kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000001005 218.0
SX3_k127_850048_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 6.809e-284 891.0
SX3_k127_850048_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 382.0
SX3_k127_850048_2 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000007643 274.0
SX3_k127_850048_3 helix_turn_helix, Arsenical Resistance Operon Repressor K07721 - - 0.00000000000000000000001407 106.0
SX3_k127_850048_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000002389 93.0
SX3_k127_850048_5 PFAM Tetratricopeptide repeat - - - 0.0000001745 61.0
SX3_k127_856205_0 Pfam:DUF650 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 355.0
SX3_k127_863214_0 COG1138 Cytochrome c biogenesis factor K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 425.0
SX3_k127_863214_1 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000002456 192.0
SX3_k127_863214_2 COG0785 Cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000008472 192.0
SX3_k127_863214_3 metal-dependent protease of the PAD1 JAB1 superfamily K20110 - 3.4.19.15 0.00000000000000000000000001243 116.0
SX3_k127_873683_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000001183 206.0
SX3_k127_873683_1 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000000000000000000000000004796 191.0
SX3_k127_873683_2 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.000000000000000000000000000000000000000002699 159.0
SX3_k127_873683_3 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000002605 86.0
SX3_k127_873683_4 Belongs to the UPF0200 family - - - 0.0000000000000004193 86.0
SX3_k127_873683_5 Protein of unknown function (DUF1524) - - - 0.0000000000001972 83.0
SX3_k127_901093_0 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 431.0
SX3_k127_901093_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 392.0
SX3_k127_901093_10 protein conserved in archaea - - - 0.00000001941 61.0
SX3_k127_901093_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 298.0
SX3_k127_901093_3 HTH-type transcriptional regulatory protein K07728 - - 0.0000000000000000000000000000000000000000000000000000002456 205.0
SX3_k127_901093_4 ORF6N domain - - - 0.00000000000000000000000000000000000000003562 153.0
SX3_k127_901093_5 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000005284 149.0
SX3_k127_901093_6 Protein of unknown function (DUF429) K09147 - - 0.00000000000000000000000000001002 125.0
SX3_k127_901093_7 cell wall binding repeat 2-containing protein - - - 0.000000000000000000002842 107.0
SX3_k127_901093_8 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.0000000000000000013 91.0
SX3_k127_901093_9 Pkd domain containing protein - - - 0.000000000000007592 86.0
SX3_k127_918071_0 Thi4 family K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 611.0
SX3_k127_918071_1 LOR SDH bifunctional enzyme conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 506.0
SX3_k127_918071_10 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.000000000000000000000000000000000000000000000000000000000000000001783 238.0
SX3_k127_918071_11 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000006844 178.0
SX3_k127_918071_12 Cytochrome C oxidase, cbb3-type, subunit III K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000008319 163.0
SX3_k127_918071_13 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000003189 139.0
SX3_k127_918071_14 DnaB-like helicase C terminal domain K08482 - - 0.00000000000000000000000000000008479 136.0
SX3_k127_918071_15 PhoU domain - - - 0.0000000000000000002165 96.0
SX3_k127_918071_16 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000001095 98.0
SX3_k127_918071_17 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000002524 57.0
SX3_k127_918071_18 Short C-terminal domain K08982 - - 0.000000003675 60.0
SX3_k127_918071_2 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 491.0
SX3_k127_918071_20 ATP cone domain - - - 0.0007178 45.0
SX3_k127_918071_3 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 463.0
SX3_k127_918071_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 409.0
SX3_k127_918071_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 370.0
SX3_k127_918071_6 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 326.0
SX3_k127_918071_7 Helix-turn-helix domain K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001069 284.0
SX3_k127_918071_8 phosphate symporter K14683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001361 284.0
SX3_k127_918071_9 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000001055 244.0
SX3_k127_938425_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.22e-249 786.0
SX3_k127_938425_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.035e-203 649.0
SX3_k127_938425_10 Helix-turn-helix diphteria tox regulatory element - - - 0.00000000000000000000000000002556 121.0
SX3_k127_938425_11 Fcf1 K07158 - - 0.00000000000000000000000006683 118.0
SX3_k127_938425_12 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.000000000000000000000001142 104.0
SX3_k127_938425_13 signal transduction protein with CBS domains - - - 0.000000000000000000000001261 108.0
SX3_k127_938425_14 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000000184 94.0
SX3_k127_938425_15 PFAM Trm112p-like protein - - - 0.00000000006164 65.0
SX3_k127_938425_16 TrkA-C domain K03499 - - 0.000001064 52.0
SX3_k127_938425_2 Ferrous iron transport protein B K04759 - - 6.065e-200 642.0
SX3_k127_938425_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 574.0
SX3_k127_938425_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 566.0
SX3_k127_938425_5 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 530.0
SX3_k127_938425_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000005554 225.0
SX3_k127_938425_7 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001674 170.0
SX3_k127_938425_8 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000378 156.0
SX3_k127_938425_9 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000001874 136.0
SX3_k127_948920_0 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 2.43e-236 759.0
SX3_k127_948920_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 427.0
SX3_k127_948920_10 PFAM Polysulphide reductase, NrfD K04015 - - 0.00000000000000000000000002653 120.0
SX3_k127_948920_11 component of anaerobic dehydrogenases - - - 0.0000000000000002026 87.0
SX3_k127_948920_12 Cytochrome c554 and c-prime - - - 0.0000003934 57.0
SX3_k127_948920_2 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 361.0
SX3_k127_948920_3 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001786 251.0
SX3_k127_948920_4 COG1148 Heterodisulfide reductase, subunit A and related polyferredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000003733 254.0
SX3_k127_948920_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000000000002794 218.0
SX3_k127_948920_6 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000002712 213.0
SX3_k127_948920_7 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000003049 138.0
SX3_k127_948920_8 Thioredoxin-like - - - 0.000000000000000000000000006069 121.0
SX3_k127_948920_9 - - - - 0.000000000000000000000000008027 114.0
SX3_k127_967921_0 Peptidase M50 - - - 0.0000000007448 61.0
SX3_k127_972404_0 histone acetyltransferase K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 566.0
SX3_k127_972404_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 366.0
SX3_k127_972404_10 Cytochrome c bacterial - - - 0.00005221 53.0
SX3_k127_972404_2 Histidine kinase A domain protein K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000004234 208.0
SX3_k127_972404_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000002 203.0
SX3_k127_972404_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000001257 148.0
SX3_k127_972404_5 Mo-molybdopterin cofactor metabolic process K03750,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.0000000000000006751 89.0
SX3_k127_972404_6 Belongs to the GbsR family - - - 0.0000000000005931 76.0
SX3_k127_972404_7 extracellular matrix structural constituent - - - 0.000000007739 66.0
SX3_k127_972404_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000001974 58.0
SX3_k127_972404_9 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000162 57.0
SX3_k127_9797_0 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 466.0
SX3_k127_9797_1 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 306.0
SX3_k127_9797_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000006747 235.0
SX3_k127_9797_3 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000007667 206.0
SX3_k127_9797_5 Belongs to the eukaryotic ribosomal protein eL33 family K02917 - - 0.0004847 50.0
SX3_k127_980464_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 352.0
SX3_k127_980464_1 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000007673 265.0
SX3_k127_980464_2 diphthine-ammonia ligase activity K06927 - 6.3.1.14 0.000000000000000000000000000000000007099 147.0
SX3_k127_980464_3 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000000000004661 141.0
SX3_k127_980464_4 PFAM Cysteine-rich small domain K07162 - - 0.0000000000006031 71.0
SX3_k127_985107_0 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 448.0
SX3_k127_985107_1 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 392.0
SX3_k127_985107_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 - 2.7.7.3 0.0000000000000000000000000000000003091 137.0
SX3_k127_985107_3 regulatory protein, arsR K03892 - - 0.0000000000000000000000000181 111.0
SX3_k127_985107_4 Putative Fe-S cluster - - - 0.000000000000000000000002111 108.0
SX3_k127_985107_5 redox-active disulfide protein 2 - - - 0.0000000000000000000001426 98.0