Overview

ID MAG03845
Name TH1_bin.1
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family
Genus
Species
Assembly information
Completeness (%) 93.58
Contamination (%) 1.1
GC content (%) 60.0
N50 (bp) 12,928
Genome size (bp) 2,261,534

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2096

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_108584_0 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 3.13e-210 674.0
TH1_k127_108584_1 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 608.0
TH1_k127_108584_10 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000004971 165.0
TH1_k127_108584_11 YGGT family K02221 - - 0.000000000000000000000000000003966 128.0
TH1_k127_108584_12 - - - - 0.00000000000000000000000009171 113.0
TH1_k127_108584_2 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 556.0
TH1_k127_108584_3 DHHA2 domain K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 555.0
TH1_k127_108584_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 481.0
TH1_k127_108584_5 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 462.0
TH1_k127_108584_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 293.0
TH1_k127_108584_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005658 256.0
TH1_k127_108584_8 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000000005022 217.0
TH1_k127_108584_9 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000001405 174.0
TH1_k127_1227005_0 Belongs to the glycosyl hydrolase 57 family - - - 4.969e-303 949.0
TH1_k127_1227005_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 589.0
TH1_k127_1227005_2 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 547.0
TH1_k127_1227005_3 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000000003695 119.0
TH1_k127_1227005_4 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000002243 66.0
TH1_k127_1238163_0 Flavodoxin - - - 7.106e-202 634.0
TH1_k127_1238163_1 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 373.0
TH1_k127_1238163_2 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000372 253.0
TH1_k127_1238163_3 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000347 179.0
TH1_k127_1238163_4 - - - - 0.00000000000213 69.0
TH1_k127_1238163_6 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 0.0000000398 62.0
TH1_k127_12426_0 GAF domain - - - 1.333e-240 773.0
TH1_k127_12426_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 562.0
TH1_k127_12426_10 PFAM Uncharacterised protein family UPF0150 - - - 0.0000007594 58.0
TH1_k127_12426_2 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 506.0
TH1_k127_12426_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 495.0
TH1_k127_12426_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 351.0
TH1_k127_12426_5 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 334.0
TH1_k127_12426_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001132 274.0
TH1_k127_12426_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000001855 231.0
TH1_k127_12426_8 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000006673 192.0
TH1_k127_12426_9 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000002403 96.0
TH1_k127_1271149_0 response regulator K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 448.0
TH1_k127_1271149_1 Histidine kinase K07709 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010288,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071284,GO:0071294,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000008781 186.0
TH1_k127_1271149_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000000000005666 169.0
TH1_k127_1271149_3 - - - - 0.00000000000000008774 87.0
TH1_k127_1271149_4 - - - - 0.000000000001819 74.0
TH1_k127_1282942_0 PFAM Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000046 264.0
TH1_k127_1282942_1 Metallo-peptidase family M12 - - - 0.000000000000000000000000792 110.0
TH1_k127_1282942_2 Sulfatase - - - 0.0000000000000000000007315 105.0
TH1_k127_1282942_3 Cephalosporin hydroxylase - - - 0.00000007945 63.0
TH1_k127_1328306_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1215.0
TH1_k127_1328306_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0 1080.0
TH1_k127_1328306_10 - - - - 0.00000000005621 65.0
TH1_k127_1328306_11 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000009263 48.0
TH1_k127_1328306_12 - - - - 0.00002382 51.0
TH1_k127_1328306_2 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 509.0
TH1_k127_1328306_3 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 395.0
TH1_k127_1328306_4 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 388.0
TH1_k127_1328306_5 2Fe-2S -binding domain K13483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005104 249.0
TH1_k127_1328306_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000001001 211.0
TH1_k127_1328306_7 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000006361 152.0
TH1_k127_1328306_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000009017 145.0
TH1_k127_1328306_9 nucleotidyltransferase activity K07075 - - 0.00000000000000000000000003856 114.0
TH1_k127_1362395_0 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 462.0
TH1_k127_1362395_1 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000000000000222 226.0
TH1_k127_1362395_2 Pfam:N_methyl_2 K02671 - - 0.0000000000000001576 85.0
TH1_k127_1362395_3 Prokaryotic N-terminal methylation motif - - - 0.000000000000002518 87.0
TH1_k127_136497_0 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 389.0
TH1_k127_136497_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 321.0
TH1_k127_136497_2 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 312.0
TH1_k127_136497_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000001445 230.0
TH1_k127_136497_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000001481 207.0
TH1_k127_136497_5 2 iron, 2 sulfur cluster binding K01465,K02823,K05784,K17828 - 1.3.1.14,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000317 205.0
TH1_k127_136497_6 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000009106 173.0
TH1_k127_136497_7 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000006359 173.0
TH1_k127_1379066_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 8.421e-207 653.0
TH1_k127_1379066_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 532.0
TH1_k127_1379066_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 287.0
TH1_k127_1379066_11 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003115 279.0
TH1_k127_1379066_12 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007567 276.0
TH1_k127_1379066_13 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000002719 239.0
TH1_k127_1379066_14 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000007257 233.0
TH1_k127_1379066_15 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000002542 207.0
TH1_k127_1379066_16 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000001591 209.0
TH1_k127_1379066_17 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000007672 176.0
TH1_k127_1379066_18 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000004114 167.0
TH1_k127_1379066_19 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000008444 160.0
TH1_k127_1379066_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 531.0
TH1_k127_1379066_20 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000004875 145.0
TH1_k127_1379066_21 RNA-binding protein containing a PIN domain K06962 - - 0.0000000000000000000000000000000002291 138.0
TH1_k127_1379066_22 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000001034 114.0
TH1_k127_1379066_23 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000245 112.0
TH1_k127_1379066_24 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000002249 101.0
TH1_k127_1379066_25 Belongs to the UPF0235 family K09131 - - 0.000000000008229 68.0
TH1_k127_1379066_26 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000002899 61.0
TH1_k127_1379066_27 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000004904 51.0
TH1_k127_1379066_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 518.0
TH1_k127_1379066_4 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 397.0
TH1_k127_1379066_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 375.0
TH1_k127_1379066_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 368.0
TH1_k127_1379066_7 NifU-like N terminal domain K04488,K07126,K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 352.0
TH1_k127_1379066_8 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 324.0
TH1_k127_1379066_9 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 292.0
TH1_k127_1383490_0 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 544.0
TH1_k127_1383490_1 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000003019 154.0
TH1_k127_1407459_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 456.0
TH1_k127_1407459_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 464.0
TH1_k127_1407459_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 369.0
TH1_k127_1407459_3 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 342.0
TH1_k127_1407459_4 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000001253 237.0
TH1_k127_1407459_5 MatE K03327 - - 0.00000000000000000000000000000000000000000000001026 180.0
TH1_k127_1407459_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000000000001188 163.0
TH1_k127_1407459_7 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000006569 55.0
TH1_k127_1535212_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 513.0
TH1_k127_1535212_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 461.0
TH1_k127_1535212_10 Transglycosylase SLT domain - - - 0.0000000006281 69.0
TH1_k127_1535212_2 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 427.0
TH1_k127_1535212_3 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 413.0
TH1_k127_1535212_4 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 404.0
TH1_k127_1535212_5 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002339 271.0
TH1_k127_1535212_6 translation release factor activity - - - 0.000000000000000000000000000000000000000004677 158.0
TH1_k127_1535212_7 TIGRFAM death-on-curing family protein K07341 - - 0.000000000000001029 86.0
TH1_k127_1535212_8 Psort location Cytoplasmic, score - - - 0.000000000000001317 90.0
TH1_k127_1535212_9 Belongs to the 'phage' integrase family K04763 - - 0.00000000000004493 79.0
TH1_k127_1557680_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 593.0
TH1_k127_1557680_1 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 548.0
TH1_k127_1557680_2 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000000007933 119.0
TH1_k127_1557680_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000003452 63.0
TH1_k127_1567292_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 8.638e-233 725.0
TH1_k127_1567292_1 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 356.0
TH1_k127_1567292_2 AMP binding - - - 0.000000000000000000000000000001251 125.0
TH1_k127_1577161_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 8.388e-240 749.0
TH1_k127_1577161_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 473.0
TH1_k127_1577161_2 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000000000000001364 213.0
TH1_k127_1577161_3 - - - - 0.000000000000000000000000000000000000000000000000001187 195.0
TH1_k127_1577161_4 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000008972 173.0
TH1_k127_1577161_5 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0000000000000000000000000002768 114.0
TH1_k127_1577161_6 carbon dioxide binding K04653,K04654 - - 0.000000002205 62.0
TH1_k127_1577161_7 His Kinase A (phosphoacceptor) domain - - - 0.00001619 56.0
TH1_k127_1590534_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000715 198.0
TH1_k127_1590781_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 610.0
TH1_k127_1590781_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 475.0
TH1_k127_1590781_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000001277 171.0
TH1_k127_1590781_3 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000000003306 136.0
TH1_k127_1593766_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000001703 218.0
TH1_k127_1593766_1 Nitroreductase family - - - 0.00000000000000000000000000000000355 135.0
TH1_k127_1618927_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 471.0
TH1_k127_1618927_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 320.0
TH1_k127_1618927_2 - - - - 0.000000000000000000000000000002124 130.0
TH1_k127_1618927_3 - - - - 0.00000000000000000000000000000217 129.0
TH1_k127_1655770_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 5.261e-246 774.0
TH1_k127_1655770_1 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 511.0
TH1_k127_1655770_2 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000009313 153.0
TH1_k127_1655770_3 Protein of unknown function (DUF559) - - - 0.0000000001991 64.0
TH1_k127_1690525_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.537e-214 678.0
TH1_k127_1690525_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 5.489e-199 631.0
TH1_k127_1690525_10 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000000002647 212.0
TH1_k127_1690525_11 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000136 176.0
TH1_k127_1690525_12 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000002806 153.0
TH1_k127_1690525_13 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000001584 109.0
TH1_k127_1690525_14 Proteasome subunit K01419 - 3.4.25.2 0.0000000000000000000001725 102.0
TH1_k127_1690525_15 - - - - 0.000000000000000000006683 96.0
TH1_k127_1690525_16 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000003526 80.0
TH1_k127_1690525_17 - - - - 0.0000001698 57.0
TH1_k127_1690525_19 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00001581 48.0
TH1_k127_1690525_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 487.0
TH1_k127_1690525_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007021 496.0
TH1_k127_1690525_4 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 412.0
TH1_k127_1690525_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 407.0
TH1_k127_1690525_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 357.0
TH1_k127_1690525_7 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 341.0
TH1_k127_1690525_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 313.0
TH1_k127_1690525_9 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001037 276.0
TH1_k127_1699309_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 593.0
TH1_k127_1699309_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 429.0
TH1_k127_1699309_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 386.0
TH1_k127_1699309_3 DNA polymerase A domain K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 294.0
TH1_k127_1699309_4 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000006055 198.0
TH1_k127_1699309_5 ZU5 domain K10380,K21440 GO:0000902,GO:0000904,GO:0001508,GO:0002027,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003205,GO:0003230,GO:0003279,GO:0003283,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005911,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006888,GO:0006928,GO:0006935,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0007009,GO:0007154,GO:0007165,GO:0007267,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007507,GO:0008015,GO:0008016,GO:0008092,GO:0008104,GO:0008150,GO:0009605,GO:0009653,GO:0009893,GO:0009987,GO:0010171,GO:0010256,GO:0010468,GO:0010522,GO:0010604,GO:0010628,GO:0010646,GO:0010880,GO:0010881,GO:0010882,GO:0010959,GO:0014069,GO:0014704,GO:0015459,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016247,GO:0016323,GO:0016328,GO:0019222,GO:0019722,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0019932,GO:0022008,GO:0022898,GO:0023051,GO:0023052,GO:0030001,GO:0030003,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030030,GO:0030048,GO:0030054,GO:0030154,GO:0030182,GO:0030315,GO:0030507,GO:0030674,GO:0031175,GO:0031224,GO:0031226,GO:0031430,GO:0031647,GO:0031672,GO:0031674,GO:0032279,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032879,GO:0032970,GO:0032989,GO:0032990,GO:0033036,GO:0033292,GO:0033365,GO:0033563,GO:0034394,GO:0034613,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035556,GO:0035637,GO:0036309,GO:0036371,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042330,GO:0042383,GO:0042391,GO:0042592,GO:0042692,GO:0043034,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043266,GO:0043268,GO:0043269,GO:0043270,GO:0043292,GO:0044057,GO:0044093,GO:0044291,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044456,GO:0044459,GO:0044464,GO:0045202,GO:0045927,GO:0046907,GO:0048193,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048522,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050821,GO:0050839,GO:0050896,GO:0051049,GO:0051050,GO:0051094,GO:0051117,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051270,GO:0051279,GO:0051282,GO:0051641,GO:0051649,GO:0051716,GO:0051899,GO:0051924,GO:0051928,GO:0055001,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055117,GO:0060047,GO:0060048,GO:0060090,GO:0060255,GO:0060306,GO:0060307,GO:0060341,GO:0061024,GO:0061061,GO:0061337,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070252,GO:0070296,GO:0070727,GO:0070838,GO:0070972,GO:0071840,GO:0071944,GO:0072359,GO:0072503,GO:0072507,GO:0072511,GO:0072657,GO:0072659,GO:0086001,GO:0086002,GO:0086003,GO:0086004,GO:0086005,GO:0086010,GO:0086012,GO:0086014,GO:0086015,GO:0086018,GO:0086019,GO:0086026,GO:0086036,GO:0086046,GO:0086065,GO:0086066,GO:0086070,GO:0086091,GO:0090257,GO:0097458,GO:0097485,GO:0098590,GO:0098771,GO:0098772,GO:0098794,GO:0098900,GO:0098901,GO:0098904,GO:0098907,GO:0098910,GO:0098984,GO:0099080,GO:0099081,GO:0099106,GO:0099512,GO:0099572,GO:0099623,GO:0120036,GO:0120039,GO:1901016,GO:1901018,GO:1901019,GO:1901021,GO:1901379,GO:1901381,GO:1903115,GO:1903169,GO:1903522,GO:1903779,GO:1904062,GO:1904064,GO:1904427,GO:1990778,GO:2001257,GO:2001259 - 0.0000000000000000000000000000001104 141.0
TH1_k127_1699309_6 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000531 113.0
TH1_k127_1699309_7 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.000000000000001142 80.0
TH1_k127_1699309_8 E-Z type HEAT repeats - - - 0.00000000000000898 86.0
TH1_k127_1714869_0 CoA binding domain K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 511.0
TH1_k127_1714869_1 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 479.0
TH1_k127_1714869_2 Putative regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000006291 217.0
TH1_k127_1714869_3 TraB family K09973 - - 0.000000000000000000000000000000000000000000000000004283 192.0
TH1_k127_1714869_4 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.00000000000000000000000000009055 115.0
TH1_k127_1714869_5 SCO1 SenC K07152 - - 0.00000005626 54.0
TH1_k127_1805112_0 Aminotransferase class-III K01845 - 5.4.3.8 1.302e-201 636.0
TH1_k127_1805112_1 Polysulphide reductase, NrfD - - - 2.145e-199 627.0
TH1_k127_1805112_10 PFAM thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000000000008776 164.0
TH1_k127_1805112_11 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000003594 162.0
TH1_k127_1805112_12 protein complex oligomerization - - - 0.000000000000000000000000000002283 128.0
TH1_k127_1805112_13 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.00000000000000000000000001548 118.0
TH1_k127_1805112_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 510.0
TH1_k127_1805112_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 434.0
TH1_k127_1805112_4 PFAM 4Fe-4S K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 431.0
TH1_k127_1805112_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 302.0
TH1_k127_1805112_6 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000000000000000000000000000004587 217.0
TH1_k127_1805112_7 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000001569 213.0
TH1_k127_1805112_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000006578 196.0
TH1_k127_1805112_9 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000008251 179.0
TH1_k127_1821859_0 Peptidase family M28 - - - 3.437e-268 846.0
TH1_k127_1864693_0 PFAM Protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 314.0
TH1_k127_1864693_1 PFAM Protein phosphatase 2C K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000005845 152.0
TH1_k127_1864693_2 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000003846 143.0
TH1_k127_1864693_3 Curli production assembly/transport component CsgG - - - 0.00000000000000007545 85.0
TH1_k127_190239_0 PFAM DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004869 273.0
TH1_k127_190239_1 EamA-like transporter family - - - 0.00000000000000000009651 89.0
TH1_k127_190239_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000003725 57.0
TH1_k127_1939837_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 527.0
TH1_k127_1939837_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000001349 192.0
TH1_k127_2044391_0 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 537.0
TH1_k127_2044391_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000005197 201.0
TH1_k127_20719_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182,K16239,K16874 - 4.1.1.61,4.1.1.98 9.927e-210 662.0
TH1_k127_20719_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 606.0
TH1_k127_20719_10 TIGRFAM radical SAM Cys-rich domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005414 270.0
TH1_k127_20719_11 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000005992 235.0
TH1_k127_20719_12 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000005991 179.0
TH1_k127_20719_13 thiamine diphosphate biosynthetic process K03154 - - 0.000000000001344 69.0
TH1_k127_20719_14 PilZ domain - - - 0.0000606 52.0
TH1_k127_20719_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 576.0
TH1_k127_20719_3 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 482.0
TH1_k127_20719_4 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 467.0
TH1_k127_20719_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 422.0
TH1_k127_20719_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 402.0
TH1_k127_20719_7 methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 394.0
TH1_k127_20719_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 352.0
TH1_k127_20719_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 323.0
TH1_k127_2246994_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1800.0
TH1_k127_2246994_1 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000003647 226.0
TH1_k127_2246994_2 Transglycosylase associated protein - - - 0.0000006028 59.0
TH1_k127_2326812_0 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 537.0
TH1_k127_2326812_1 Cytochrome c - - - 0.00000000000000000000006713 110.0
TH1_k127_2426010_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 7.564e-280 867.0
TH1_k127_2426010_1 Von Willebrand factor type A K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 499.0
TH1_k127_2426010_10 Domain of unknown function (DUF4262) - - - 0.00000001765 61.0
TH1_k127_2426010_11 gag-polyprotein putative aspartyl protease K06985 - - 0.000001108 58.0
TH1_k127_2426010_2 CbbQ/NirQ/NorQ C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 392.0
TH1_k127_2426010_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 331.0
TH1_k127_2426010_4 PFAM metal-dependent phosphohydrolase HD sub - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 332.0
TH1_k127_2426010_5 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 328.0
TH1_k127_2426010_6 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 298.0
TH1_k127_2426010_7 PFAM RES domain - - - 0.000000000000000000000000000000000203 139.0
TH1_k127_2426010_8 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000002061 130.0
TH1_k127_2426010_9 Protein of unknown function (DUF2384) - - - 0.0000000000001462 78.0
TH1_k127_2443449_0 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 349.0
TH1_k127_2443449_1 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001256 283.0
TH1_k127_2443449_2 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000976 256.0
TH1_k127_2443449_3 THUMP - - - 0.00006322 51.0
TH1_k127_2468941_0 phosphorelay sensor kinase activity K01120,K01768,K02486,K11356,K11894,K11913 - 2.7.13.3,3.1.4.17,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 509.0
TH1_k127_2468941_1 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 304.0
TH1_k127_2468941_2 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000000000000000000000155 231.0
TH1_k127_2468941_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000007293 152.0
TH1_k127_2491665_0 NosL - - - 0.00000000000000000000000000000000000000000005894 165.0
TH1_k127_2491665_1 citrate synthase K01647 - 2.3.3.1 0.000000000000000000000000000000506 124.0
TH1_k127_2524897_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 511.0
TH1_k127_2524897_1 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 448.0
TH1_k127_2524897_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007572 272.0
TH1_k127_2524897_3 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000005398 200.0
TH1_k127_2524897_4 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000000000003474 159.0
TH1_k127_2524897_5 lyase activity - - - 0.000000000000000000000000000000000003037 145.0
TH1_k127_2524897_6 deoxyhypusine monooxygenase activity K05385 - - 0.000000000000000002002 89.0
TH1_k127_2528133_0 Belongs to the ClpA ClpB family K11907 - - 2.194e-321 1005.0
TH1_k127_2528133_1 Type VI secretion system, TssF K11896 - - 4.929e-243 764.0
TH1_k127_2528133_2 Phage late control gene D protein (GPD) K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 614.0
TH1_k127_2528133_3 type VI secretion protein K11900,K11901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 454.0
TH1_k127_2528133_4 type VI secretion protein K11895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000123 285.0
TH1_k127_2528133_5 Gene 25-like lysozyme K11897 - - 0.000000000000000000000000000000000000171 147.0
TH1_k127_2528133_6 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000001889 81.0
TH1_k127_2556133_0 Protein of unknown function (DUF3011) - - - 0.000000000000000000000000000000000000000000000000000000002219 211.0
TH1_k127_2556133_1 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000007125 117.0
TH1_k127_2556133_2 Sigma-54 interaction domain - - - 0.000000126 56.0
TH1_k127_2556133_3 FR47-like protein - - - 0.00001574 53.0
TH1_k127_2556133_4 3-demethylubiquinone-9 3-methyltransferase - - - 0.000025 48.0
TH1_k127_2566544_0 ImcF-related N-terminal domain K11891 - - 0.0 1296.0
TH1_k127_2566544_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 1.676e-208 651.0
TH1_k127_2566544_10 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 - - - 0.000000000000000000000000000000000000000000000000007624 188.0
TH1_k127_2566544_11 - - - - 0.00000000000000000000000000000000000004769 153.0
TH1_k127_2566544_2 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 609.0
TH1_k127_2566544_3 ImpA, N-terminal, type VI secretion system K11902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 423.0
TH1_k127_2566544_4 Type VI secretion system protein DotU K11892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 289.0
TH1_k127_2566544_5 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006522 266.0
TH1_k127_2566544_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001282 270.0
TH1_k127_2566544_7 ImpA, N-terminal, type VI secretion system K11910 - - 0.00000000000000000000000000000000000000000000000000000003543 209.0
TH1_k127_2566544_8 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.00000000000000000000000000000000000000000000000000007029 197.0
TH1_k127_2566544_9 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 0.000000000000000000000000000000000000000000000000001781 185.0
TH1_k127_2569792_0 Cobalamin synthesis G N-terminal K13541 - 2.1.1.131,3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 479.0
TH1_k127_2569792_1 Biotin-protein ligase, N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 312.0
TH1_k127_2569792_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000004758 67.0
TH1_k127_2569792_3 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.00000343 53.0
TH1_k127_2569792_4 DsrE/DsrF-like family K07236 - - 0.0001924 49.0
TH1_k127_2569792_5 PFAM DsrE K07235 - - 0.000838 46.0
TH1_k127_2651791_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000001706 223.0
TH1_k127_2651791_1 pyridine nucleotide-disulfide oxidoreductase K03885 - 1.6.99.3 0.0000000000007907 70.0
TH1_k127_2664540_0 Clostripain family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 608.0
TH1_k127_2664540_1 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 530.0
TH1_k127_2664540_10 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000002225 106.0
TH1_k127_2664540_12 GDP-mannose mannosyl hydrolase activity - - - 0.0000000000000000000123 94.0
TH1_k127_2664540_14 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000006691 74.0
TH1_k127_2664540_2 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 523.0
TH1_k127_2664540_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 432.0
TH1_k127_2664540_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 292.0
TH1_k127_2664540_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000000001085 186.0
TH1_k127_2664540_6 - - - - 0.000000000000000000000000000000000000000000000004518 175.0
TH1_k127_2664540_7 Protein of unknown function (DUF3124) - - - 0.00000000000000000000000000000000000000000000003537 174.0
TH1_k127_2664540_8 Ion channel - - - 0.00000000000000000000000000000001721 129.0
TH1_k127_2664540_9 - - - - 0.00000000000000000000000006123 108.0
TH1_k127_2671970_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 611.0
TH1_k127_2671970_1 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 609.0
TH1_k127_2671970_2 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 514.0
TH1_k127_2690039_0 Site-specific recombinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 539.0
TH1_k127_2774076_0 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 340.0
TH1_k127_2774076_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 323.0
TH1_k127_2774076_2 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003054 268.0
TH1_k127_2774076_3 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000004435 199.0
TH1_k127_2774076_4 HEAT repeats - - - 0.000000000000000000000000000000000000000000003853 183.0
TH1_k127_2774076_5 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000012 126.0
TH1_k127_2795403_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 521.0
TH1_k127_2795403_1 PIN domain - - - 0.00000000000000000005184 94.0
TH1_k127_2795403_2 Bacterial antitoxin of type II TA system, VapB - - - 0.0006879 45.0
TH1_k127_2866370_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 530.0
TH1_k127_2866370_1 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000008272 148.0
TH1_k127_2871183_0 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 548.0
TH1_k127_2871183_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 538.0
TH1_k127_2871183_10 membrane K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 317.0
TH1_k127_2871183_11 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 300.0
TH1_k127_2871183_12 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004578 244.0
TH1_k127_2871183_13 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000001315 233.0
TH1_k127_2871183_14 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000001775 227.0
TH1_k127_2871183_15 Aminotransferase K00814,K14260 GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0040007,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 0.000000000000000000000000000000000000000000000000000000000000006834 233.0
TH1_k127_2871183_16 Phosphomethylpyrimidine kinase K00868,K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000003369 219.0
TH1_k127_2871183_17 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000006441 202.0
TH1_k127_2871183_18 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000725 205.0
TH1_k127_2871183_19 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000001293 183.0
TH1_k127_2871183_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 518.0
TH1_k127_2871183_20 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000002434 145.0
TH1_k127_2871183_21 - - - - 0.00000000000000000000000000002146 121.0
TH1_k127_2871183_23 Protein of unknown function (DUF3617) - - - 0.0000000000000000002874 93.0
TH1_k127_2871183_24 MacB-like periplasmic core domain K02004 - - 0.000000000000003028 82.0
TH1_k127_2871183_26 - - - - 0.0000001062 65.0
TH1_k127_2871183_28 - - - - 0.000004384 53.0
TH1_k127_2871183_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 476.0
TH1_k127_2871183_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 419.0
TH1_k127_2871183_5 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 402.0
TH1_k127_2871183_6 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 396.0
TH1_k127_2871183_7 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 385.0
TH1_k127_2871183_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 378.0
TH1_k127_2871183_9 response regulator K07664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 325.0
TH1_k127_2896472_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 2.556e-229 721.0
TH1_k127_2896472_1 PFAM RES domain - - - 0.00000000000000000000000000000008234 133.0
TH1_k127_2896472_2 Protein of unknown function (DUF2384) - - - 0.000000000000000007046 90.0
TH1_k127_2896472_3 lyase activity - - - 0.00006198 49.0
TH1_k127_3023682_0 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 561.0
TH1_k127_3023682_1 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337,K21008 GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000001375 112.0
TH1_k127_3023682_2 - - - - 0.0000000000000000006999 98.0
TH1_k127_303653_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.995e-197 623.0
TH1_k127_303653_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 407.0
TH1_k127_303653_10 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000005142 139.0
TH1_k127_303653_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000595 125.0
TH1_k127_303653_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 381.0
TH1_k127_303653_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 351.0
TH1_k127_303653_4 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 299.0
TH1_k127_303653_5 Redoxin K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001705 250.0
TH1_k127_303653_6 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000009009 194.0
TH1_k127_303653_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000001053 185.0
TH1_k127_303653_8 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000001907 142.0
TH1_k127_3056801_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001851 242.0
TH1_k127_3056801_1 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000003825 199.0
TH1_k127_3056801_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000004351 149.0
TH1_k127_3056801_3 Glycosyltransferase Family 4 - - - 0.0000000000000000007086 99.0
TH1_k127_3070798_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 6.517e-203 636.0
TH1_k127_3070798_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 594.0
TH1_k127_3070798_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 426.0
TH1_k127_3070798_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000222 62.0
TH1_k127_3132145_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 604.0
TH1_k127_3132145_1 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 466.0
TH1_k127_3132145_10 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.000000000000000000000000000000000000003166 153.0
TH1_k127_3132145_11 iron-sulfur cluster assembly - - - 0.0000000000000000000000001955 107.0
TH1_k127_3132145_12 General secretion pathway protein C K02452 - - 0.0000000000000000003181 98.0
TH1_k127_3132145_2 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 370.0
TH1_k127_3132145_3 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 371.0
TH1_k127_3132145_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 346.0
TH1_k127_3132145_5 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 349.0
TH1_k127_3132145_6 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 341.0
TH1_k127_3132145_7 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 338.0
TH1_k127_3132145_8 Belongs to the MurCDEF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 336.0
TH1_k127_3132145_9 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000008822 169.0
TH1_k127_3189472_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.041e-206 661.0
TH1_k127_3189472_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 376.0
TH1_k127_3189472_2 ATP adenylyltransferase K00988 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 321.0
TH1_k127_3189472_3 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.0000000000000009021 76.0
TH1_k127_3189472_5 Bacterial Ig-like domain (group 2) - - - 0.00003292 49.0
TH1_k127_3189472_6 - - - - 0.00008545 51.0
TH1_k127_32103_0 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 6.068e-279 893.0
TH1_k127_32103_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 589.0
TH1_k127_32103_2 - - - - 0.000000000000000000000000000000000000000000000000000000001159 213.0
TH1_k127_3222173_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 1.621e-288 911.0
TH1_k127_3222173_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 557.0
TH1_k127_3222173_2 SMART Cold shock protein K03704 - - 0.000000000000000000000005537 103.0
TH1_k127_3222173_3 belongs to the CobB CobQ family K06873 - - 0.0000000000000000001908 89.0
TH1_k127_3241118_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 6.539e-223 698.0
TH1_k127_3241118_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 400.0
TH1_k127_3241118_10 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008382 272.0
TH1_k127_3241118_11 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000006296 247.0
TH1_k127_3241118_12 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000004701 232.0
TH1_k127_3241118_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000145 231.0
TH1_k127_3241118_14 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000184 226.0
TH1_k127_3241118_15 PFAM Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000006258 226.0
TH1_k127_3241118_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000005538 201.0
TH1_k127_3241118_17 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002961 196.0
TH1_k127_3241118_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000003919 192.0
TH1_k127_3241118_19 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000002889 177.0
TH1_k127_3241118_2 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 403.0
TH1_k127_3241118_20 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000001166 171.0
TH1_k127_3241118_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000001016 168.0
TH1_k127_3241118_22 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000001741 168.0
TH1_k127_3241118_23 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000004178 153.0
TH1_k127_3241118_24 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000005799 153.0
TH1_k127_3241118_25 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000004884 149.0
TH1_k127_3241118_26 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000009912 147.0
TH1_k127_3241118_27 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000001604 129.0
TH1_k127_3241118_28 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000061 121.0
TH1_k127_3241118_29 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001316 117.0
TH1_k127_3241118_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 370.0
TH1_k127_3241118_30 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001273 103.0
TH1_k127_3241118_31 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000003822 81.0
TH1_k127_3241118_32 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000467 74.0
TH1_k127_3241118_33 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001722 70.0
TH1_k127_3241118_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 346.0
TH1_k127_3241118_5 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 348.0
TH1_k127_3241118_6 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 332.0
TH1_k127_3241118_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 297.0
TH1_k127_3241118_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 288.0
TH1_k127_3241118_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 289.0
TH1_k127_3262584_0 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000004303 92.0
TH1_k127_3262584_1 - - - - 0.000000000007275 78.0
TH1_k127_3262584_3 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - 0.00000007842 62.0
TH1_k127_3271699_0 Glycosyl hydrolase family 57 - - - 6.318e-226 723.0
TH1_k127_3271699_1 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 346.0
TH1_k127_3271699_2 binding domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008687 322.0
TH1_k127_3271699_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000007882 183.0
TH1_k127_3271699_4 Enzyme of the cupin superfamily K06995 - - 0.000000000000000009478 86.0
TH1_k127_3271699_5 cell cycle K05589,K12065,K13052 - - 0.0000001293 58.0
TH1_k127_3304591_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 536.0
TH1_k127_3304591_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 321.0
TH1_k127_3304591_2 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009144 254.0
TH1_k127_3304591_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000007623 239.0
TH1_k127_3304591_4 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000000001149 179.0
TH1_k127_3304591_5 Helix-turn-helix domain - - - 0.0000000000000000000000000000000001469 144.0
TH1_k127_3304591_6 - - - - 0.00000000000000000000000003452 121.0
TH1_k127_3304591_7 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000003697 68.0
TH1_k127_335997_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1014.0
TH1_k127_335997_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000001222 59.0
TH1_k127_3460911_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 367.0
TH1_k127_3460911_1 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000345 86.0
TH1_k127_3460911_2 - - - - 0.000000001341 66.0
TH1_k127_3602165_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 2.066e-236 747.0
TH1_k127_3602165_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 323.0
TH1_k127_3602165_2 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000004501 111.0
TH1_k127_3602165_3 Helix-turn-helix domain - - - 0.00000000000000000000005078 109.0
TH1_k127_3602165_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000003697 68.0
TH1_k127_3607629_0 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 440.0
TH1_k127_3607629_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 376.0
TH1_k127_3607629_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 361.0
TH1_k127_3607629_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000002064 135.0
TH1_k127_3607629_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000002723 100.0
TH1_k127_3658404_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.298e-306 958.0
TH1_k127_3658404_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.586e-297 926.0
TH1_k127_3658404_10 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 353.0
TH1_k127_3658404_11 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000264 286.0
TH1_k127_3658404_12 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001807 258.0
TH1_k127_3658404_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000001957 209.0
TH1_k127_3658404_14 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000001108 196.0
TH1_k127_3658404_15 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000006047 146.0
TH1_k127_3658404_16 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000006335 134.0
TH1_k127_3658404_17 Thiamine-binding protein - - - 0.0000000000000000000000000000000001085 135.0
TH1_k127_3658404_19 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000003889 88.0
TH1_k127_3658404_2 Bacterial regulatory protein, Fis family K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 612.0
TH1_k127_3658404_20 Protein of unknown function (DUF721) - - - 0.0000000004638 67.0
TH1_k127_3658404_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 589.0
TH1_k127_3658404_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 546.0
TH1_k127_3658404_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 466.0
TH1_k127_3658404_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 449.0
TH1_k127_3658404_7 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 408.0
TH1_k127_3658404_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 347.0
TH1_k127_3658404_9 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 342.0
TH1_k127_3671440_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1184.0
TH1_k127_3671440_1 Phosphoglycerate kinase K00927 - 2.7.2.3 6.126e-201 632.0
TH1_k127_3671440_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 567.0
TH1_k127_3671440_3 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 496.0
TH1_k127_3671440_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 406.0
TH1_k127_3671440_5 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 382.0
TH1_k127_3671440_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 358.0
TH1_k127_3671440_7 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000009647 259.0
TH1_k127_3671440_8 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000002312 177.0
TH1_k127_3674493_0 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000002181 238.0
TH1_k127_3674493_1 Conserved repeat domain - - - 0.0000000000000000001292 105.0
TH1_k127_3674493_2 Subtilase family - - - 0.0003894 54.0
TH1_k127_3677918_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 5.7e-322 1008.0
TH1_k127_3677918_1 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 574.0
TH1_k127_3677918_10 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000003525 108.0
TH1_k127_3677918_11 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000003422 102.0
TH1_k127_3677918_12 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000002248 94.0
TH1_k127_3677918_13 domain protein - - - 0.00000000000000000001793 92.0
TH1_k127_3677918_14 RecX family K03565 - - 0.000000005035 63.0
TH1_k127_3677918_15 ATP synthase, subunit b - - - 0.000001307 54.0
TH1_k127_3677918_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 534.0
TH1_k127_3677918_3 NADPH-quinone reductase (modulator of drug activity B) - - - 0.00000000000000000000000000000000000000000000000000000000000000353 228.0
TH1_k127_3677918_4 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.00000000000000000000000000000000000000000000000000000000001334 211.0
TH1_k127_3677918_5 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000001126 201.0
TH1_k127_3677918_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.000000000000000000000000000000000000002475 149.0
TH1_k127_3677918_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001961 143.0
TH1_k127_3677918_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000000001564 145.0
TH1_k127_3677918_9 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.000000000000000000000000009307 115.0
TH1_k127_3685456_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 434.0
TH1_k127_3685456_1 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 416.0
TH1_k127_3685456_10 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000008313 160.0
TH1_k127_3685456_11 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000004879 118.0
TH1_k127_3685456_12 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.000000000000000000000008585 109.0
TH1_k127_3685456_13 Protein of unknown function DUF86 - - - 0.00000000001934 68.0
TH1_k127_3685456_14 Tetratricopeptide repeat protein - - - 0.00001221 55.0
TH1_k127_3685456_15 sulfur relay protein TusB DsrH K07237 - - 0.00001274 51.0
TH1_k127_3685456_16 Sulfur relay protein TusC DsrF K07236 - - 0.00002731 51.0
TH1_k127_3685456_17 DsrE/DsrF-like family K07235 - - 0.00009549 48.0
TH1_k127_3685456_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 379.0
TH1_k127_3685456_3 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 385.0
TH1_k127_3685456_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 358.0
TH1_k127_3685456_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 321.0
TH1_k127_3685456_6 zinc ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002216 261.0
TH1_k127_3685456_7 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000001129 203.0
TH1_k127_3685456_8 Molybdate transporter of MFS superfamily - - - 0.000000000000000000000000000000000000000000000000000006226 207.0
TH1_k127_3685456_9 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000001463 190.0
TH1_k127_3694654_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1528.0
TH1_k127_3694654_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 610.0
TH1_k127_3694654_10 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 286.0
TH1_k127_3694654_11 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000004062 241.0
TH1_k127_3694654_12 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000002262 197.0
TH1_k127_3694654_13 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000423 194.0
TH1_k127_3694654_14 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000000000000000000009777 154.0
TH1_k127_3694654_15 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000002402 133.0
TH1_k127_3694654_16 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000001488 95.0
TH1_k127_3694654_17 Belongs to the 'phage' integrase family - - - 0.000000000000000002557 87.0
TH1_k127_3694654_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 529.0
TH1_k127_3694654_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 475.0
TH1_k127_3694654_4 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 422.0
TH1_k127_3694654_5 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 383.0
TH1_k127_3694654_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 372.0
TH1_k127_3694654_7 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 333.0
TH1_k127_3694654_8 CO dehydrogenase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 316.0
TH1_k127_3694654_9 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 285.0
TH1_k127_369619_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 378.0
TH1_k127_369619_1 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 318.0
TH1_k127_369619_2 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 312.0
TH1_k127_369619_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000004283 232.0
TH1_k127_369619_4 Histidine kinase - - - 0.00000000000000000000000002057 110.0
TH1_k127_369619_5 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000003651 115.0
TH1_k127_3706271_0 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 512.0
TH1_k127_3706271_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 383.0
TH1_k127_3706271_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 352.0
TH1_k127_3706271_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 351.0
TH1_k127_3706271_4 Di-haem cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 302.0
TH1_k127_3706271_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 286.0
TH1_k127_3706271_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003871 250.0
TH1_k127_3706271_7 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000003237 172.0
TH1_k127_3706271_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000003132 161.0
TH1_k127_3725465_0 GTP-binding protein TypA K06207 - - 3.367e-269 841.0
TH1_k127_3725465_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002522 252.0
TH1_k127_3725465_2 part of a sulfur-relay system K11179 - - 0.000000000000000008648 84.0
TH1_k127_3725465_3 Domain of unknown function (DUF3786) - - - 0.0000000000000001211 90.0
TH1_k127_3725465_4 Flavin reductase like domain - - - 0.0004509 46.0
TH1_k127_3731260_0 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000005227 214.0
TH1_k127_3731260_1 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000002547 187.0
TH1_k127_3731260_3 oxidoreductase gamma subunit K00177 - 1.2.7.3 0.000000001562 63.0
TH1_k127_3742116_0 Elongation factor G, domain IV K02355 - - 2.209e-313 973.0
TH1_k127_3742116_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.931e-251 784.0
TH1_k127_3742116_10 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 404.0
TH1_k127_3742116_11 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 347.0
TH1_k127_3742116_12 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 312.0
TH1_k127_3742116_13 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 299.0
TH1_k127_3742116_14 Histidine kinase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001969 263.0
TH1_k127_3742116_15 PAS domain K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000003886 261.0
TH1_k127_3742116_16 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000009105 245.0
TH1_k127_3742116_17 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008886 249.0
TH1_k127_3742116_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.0000000000000000000000000000000000000000000000001863 187.0
TH1_k127_3742116_19 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000001361 184.0
TH1_k127_3742116_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.696e-246 772.0
TH1_k127_3742116_20 chemotaxis K03408 - - 0.0000000000000000000000000000000000000008321 152.0
TH1_k127_3742116_21 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000004429 145.0
TH1_k127_3742116_22 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000009544 141.0
TH1_k127_3742116_23 ThiS family K03636 - - 0.000000000000000000000000000000000592 132.0
TH1_k127_3742116_25 - - - - 0.00000000000000000000000000000005666 125.0
TH1_k127_3742116_26 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000003875 126.0
TH1_k127_3742116_28 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000009187 126.0
TH1_k127_3742116_29 NIL - - - 0.000000000000000000000000001201 114.0
TH1_k127_3742116_3 Type II/IV secretion system protein K02454,K02652 - - 1.36e-202 646.0
TH1_k127_3742116_30 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000000009751 79.0
TH1_k127_3742116_31 PFAM Ig domain protein, group 1 domain protein K20276 - - 0.000000000214 74.0
TH1_k127_3742116_32 Pilus assembly protein, PilP K02664,K02665 - - 0.0000000002828 68.0
TH1_k127_3742116_4 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 582.0
TH1_k127_3742116_5 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 508.0
TH1_k127_3742116_6 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 507.0
TH1_k127_3742116_7 Signal transducing histidine kinase homodimeric K03407,K13490 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 516.0
TH1_k127_3742116_8 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 465.0
TH1_k127_3742116_9 AIR synthase related protein, N-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 420.0
TH1_k127_3759958_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2215.0
TH1_k127_3759958_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2006.0
TH1_k127_3759958_10 structural constituent of ribosome K02913 - - 0.00000000000000008707 82.0
TH1_k127_3759958_11 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000001367 80.0
TH1_k127_3759958_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000467 74.0
TH1_k127_3759958_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 369.0
TH1_k127_3759958_3 TrkA-N domain K03455,K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 366.0
TH1_k127_3759958_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001854 273.0
TH1_k127_3759958_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008199 238.0
TH1_k127_3759958_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000006927 192.0
TH1_k127_3759958_7 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000524 144.0
TH1_k127_3759958_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000156 143.0
TH1_k127_3759958_9 Domain of unknown function (DUF4136) - - - 0.0000000000000000000001802 105.0
TH1_k127_3774116_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 351.0
TH1_k127_3774116_1 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 291.0
TH1_k127_3774116_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001733 169.0
TH1_k127_3788255_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1251.0
TH1_k127_3788255_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.622e-287 911.0
TH1_k127_3788255_10 Thioredoxin-like - - - 0.000000000000000000000000000000000000000002698 162.0
TH1_k127_3788255_11 - - - - 0.00000000000000000000000000000000000001107 153.0
TH1_k127_3788255_12 COG3209 Rhs family protein - - - 0.00000000000000000000000000000002141 139.0
TH1_k127_3788255_13 cellulase activity K12287 - - 0.0000000000000001923 89.0
TH1_k127_3788255_14 Prokaryotic N-terminal methylation motif - - - 0.0000000002981 64.0
TH1_k127_3788255_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 297.0
TH1_k127_3788255_3 Subtilase family K20486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001619 295.0
TH1_k127_3788255_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000001386 229.0
TH1_k127_3788255_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000007322 231.0
TH1_k127_3788255_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000007524 213.0
TH1_k127_3788255_7 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000002808 200.0
TH1_k127_3788255_8 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000000000005152 193.0
TH1_k127_3788255_9 Poly-gamma-glutamate hydrolase - - - 0.0000000000000000000000000000000000000000004645 165.0
TH1_k127_3792402_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 374.0
TH1_k127_3792402_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 364.0
TH1_k127_3792402_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002124 246.0
TH1_k127_3792402_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000001147 138.0
TH1_k127_3805594_0 Heat shock 70 kDa protein K04043 - - 1.1e-322 998.0
TH1_k127_3805594_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 490.0
TH1_k127_3805594_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000001191 164.0
TH1_k127_3805594_11 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000001647 130.0
TH1_k127_3805594_12 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000008013 121.0
TH1_k127_3805594_13 Transport permease protein K01992 - - 0.0000000000000000000000002925 113.0
TH1_k127_3805594_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 486.0
TH1_k127_3805594_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 429.0
TH1_k127_3805594_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 337.0
TH1_k127_3805594_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 326.0
TH1_k127_3805594_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
TH1_k127_3805594_7 PINc domain ribonuclease K09006 - - 0.000000000000000000000000000000000000000000000000000000000000000009293 234.0
TH1_k127_3805594_8 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000003554 229.0
TH1_k127_3805594_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000003652 173.0
TH1_k127_3814667_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 369.0
TH1_k127_3814667_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 346.0
TH1_k127_3814667_2 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008546 264.0
TH1_k127_3814667_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000003672 239.0
TH1_k127_3814667_4 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000002314 188.0
TH1_k127_3815670_0 TIGRFAM ATPase, FliI YscN family K02412,K03224 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 508.0
TH1_k127_3815670_1 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 416.0
TH1_k127_3815670_10 PFAM Flagellar hook-length control protein K02414 - - 0.00009106 54.0
TH1_k127_3815670_11 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00025 45.0
TH1_k127_3815670_2 Flagellar basal body protein FlaE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 360.0
TH1_k127_3815670_3 FliG middle domain K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001521 279.0
TH1_k127_3815670_4 Flagella basal body rod protein K02388 - - 0.00000000000000000000000000000000000002137 149.0
TH1_k127_3815670_5 Ankyrin repeat K05643 - - 0.000000000000000000000000000000000006058 153.0
TH1_k127_3815670_6 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000004158 143.0
TH1_k127_3815670_7 Flagellar assembly protein FliH K02411 - - 0.00000000000001213 81.0
TH1_k127_3815670_8 PFAM MgtE intracellular K02383 - - 0.00000000000001554 81.0
TH1_k127_3815670_9 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000001708 67.0
TH1_k127_3819507_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 1.608e-211 670.0
TH1_k127_3819507_1 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000425 203.0
TH1_k127_3819507_2 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000004212 76.0
TH1_k127_3819507_3 PFAM Sulphate transporter K03321 - - 0.00000113 52.0
TH1_k127_3823481_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 4.611e-194 611.0
TH1_k127_3823481_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 327.0
TH1_k127_3823481_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000001971 251.0
TH1_k127_3823481_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000006532 197.0
TH1_k127_3823481_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000001457 100.0
TH1_k127_3871494_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.75e-310 970.0
TH1_k127_3871494_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.367e-230 721.0
TH1_k127_3871494_10 SOUL heme-binding protein - - - 0.000000000000004068 77.0
TH1_k127_3871494_11 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0002416 44.0
TH1_k127_3871494_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 433.0
TH1_k127_3871494_3 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 419.0
TH1_k127_3871494_4 PFAM Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002845 278.0
TH1_k127_3871494_5 - - - - 0.00000000000000000000000000000000000000000000000000001347 193.0
TH1_k127_3871494_6 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.000000000000000000000000000000000000000000003023 170.0
TH1_k127_3871494_7 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000002898 152.0
TH1_k127_3871494_8 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000002361 135.0
TH1_k127_3883066_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002713 269.0
TH1_k127_3883066_1 Histidine kinase - - - 0.00000000000000000000000000001654 138.0
TH1_k127_3883066_2 Transcriptional regulator K11921,K19338 - - 0.0000184 48.0
TH1_k127_3894356_0 Protein conserved in bacteria - - - 2.97e-244 780.0
TH1_k127_3894356_1 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000036 276.0
TH1_k127_3927967_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 462.0
TH1_k127_3927967_1 glucose sorbosone K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 437.0
TH1_k127_3927967_11 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0005006 48.0
TH1_k127_3927967_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 360.0
TH1_k127_3927967_3 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 320.0
TH1_k127_3927967_4 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 302.0
TH1_k127_3927967_5 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007145 265.0
TH1_k127_3927967_6 PFAM ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002724 240.0
TH1_k127_3927967_7 MarC family integral membrane protein - - - 0.000000000000000000000000000000000000000000000000001357 190.0
TH1_k127_3927967_9 Protein of unknown function (DUF2628) - - - 0.0000000000000000000000000007527 118.0
TH1_k127_3943431_0 curli production assembly transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 289.0
TH1_k127_3951139_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 7.992e-215 674.0
TH1_k127_3951139_1 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 3.799e-205 650.0
TH1_k127_3951139_10 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000001081 152.0
TH1_k127_3951139_11 - - - - 0.000000000000000000000000000000000000007852 150.0
TH1_k127_3951139_12 E3 Ubiquitin ligase - - - 0.00002071 56.0
TH1_k127_3951139_2 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 4.107e-202 636.0
TH1_k127_3951139_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 3.625e-196 624.0
TH1_k127_3951139_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 473.0
TH1_k127_3951139_5 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000002043 228.0
TH1_k127_3951139_6 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000001057 214.0
TH1_k127_3951139_7 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000008402 206.0
TH1_k127_3951139_8 amino acid-binding ACT - - - 0.0000000000000000000000000000000000000000000000000000000001527 207.0
TH1_k127_3951139_9 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000007094 189.0
TH1_k127_395232_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 572.0
TH1_k127_395232_1 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 361.0
TH1_k127_395232_10 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.000000000000000000000000001182 117.0
TH1_k127_395232_11 Response regulator, receiver - - - 0.0000000001376 68.0
TH1_k127_395232_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 314.0
TH1_k127_395232_3 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 293.0
TH1_k127_395232_4 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003714 281.0
TH1_k127_395232_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000009074 234.0
TH1_k127_395232_6 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000007134 230.0
TH1_k127_395232_7 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000612 183.0
TH1_k127_395232_8 HNH nucleases - - - 0.00000000000000000000000000000000000000000001163 166.0
TH1_k127_395232_9 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000002308 130.0
TH1_k127_3978385_0 Domain of unknown function (DUF4139) - - - 4.73e-197 625.0
TH1_k127_3978385_1 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 606.0
TH1_k127_3978385_10 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.0000006655 61.0
TH1_k127_3978385_11 General secretion pathway protein H K02457 - - 0.00002192 53.0
TH1_k127_3978385_12 HNH nucleases K07451 - - 0.0003197 48.0
TH1_k127_3978385_13 Subtilase family K08651 - 3.4.21.66 0.0003627 47.0
TH1_k127_3978385_2 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000005518 226.0
TH1_k127_3978385_3 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000004458 200.0
TH1_k127_3978385_4 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000001436 207.0
TH1_k127_3978385_5 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000008468 129.0
TH1_k127_3978385_6 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000000000000001358 113.0
TH1_k127_3978385_7 - - - - 0.000000000006032 76.0
TH1_k127_3978385_8 general secretion pathway protein K02456,K02457,K02458,K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000001734 63.0
TH1_k127_3978385_9 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - 0.0000001274 62.0
TH1_k127_3981773_0 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 455.0
TH1_k127_3981773_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000009299 171.0
TH1_k127_3981773_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000539 43.0
TH1_k127_3992822_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 492.0
TH1_k127_3992822_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 418.0
TH1_k127_4011787_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 3.585e-196 617.0
TH1_k127_4011787_1 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 582.0
TH1_k127_4011787_2 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 525.0
TH1_k127_4011787_3 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 359.0
TH1_k127_4011787_4 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000001 202.0
TH1_k127_4011787_5 - - - - 0.000000000000000000000000000004454 126.0
TH1_k127_4018345_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 5.747e-275 853.0
TH1_k127_4018345_1 Domains REC, sigma54 interaction, HTH8 K02481 - - 1.545e-201 638.0
TH1_k127_4018345_2 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 554.0
TH1_k127_4018345_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 509.0
TH1_k127_4018345_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 432.0
TH1_k127_4018345_5 eight transmembrane protein EpsH - - - 0.00000000000000000000000000000000000000000005631 171.0
TH1_k127_4018345_6 VanZ like family - - - 0.000000000000000000000000000000000000000259 164.0
TH1_k127_4018345_7 PEP-CTERM motif - - - 0.00000000000000000006662 98.0
TH1_k127_4018345_8 PFAM VanZ - - - 0.0000000002409 70.0
TH1_k127_4066949_0 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 437.0
TH1_k127_4066949_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 344.0
TH1_k127_4066949_3 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000005563 246.0
TH1_k127_4066949_4 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000003071 108.0
TH1_k127_4066949_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.00000000000000001172 82.0
TH1_k127_4066949_6 protein secretion K03116,K03117 - - 0.00000000000006905 81.0
TH1_k127_4203704_0 Conserved hypothetical protein 698 - - - 5.147e-241 753.0
TH1_k127_4203704_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000009979 154.0
TH1_k127_4203704_2 AMP binding - - - 0.0000000000000000000000002407 110.0
TH1_k127_4226153_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1187.0
TH1_k127_4226153_1 TIGRFAM 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 489.0
TH1_k127_4226153_11 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000009018 70.0
TH1_k127_4226153_12 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000001359 72.0
TH1_k127_4226153_13 - - - - 0.00000000002014 68.0
TH1_k127_4226153_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 386.0
TH1_k127_4226153_3 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 354.0
TH1_k127_4226153_4 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000002912 261.0
TH1_k127_4226153_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000002712 233.0
TH1_k127_4226153_6 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000007166 213.0
TH1_k127_4226153_7 TIGRFAM molybdenum cofactor synthesis domain - - - 0.0000000000000000000000000000000000000000000000000000000002734 207.0
TH1_k127_4226153_8 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.000000000000000000000000000001122 134.0
TH1_k127_4226153_9 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000001748 113.0
TH1_k127_4229026_0 COG0591 Na proline symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 316.0
TH1_k127_4229026_1 Sigma-54 factor interaction domain-containing protein K07713 - - 0.0000000000000936 75.0
TH1_k127_4248639_0 Tetratricopeptide repeat - - - 3.724e-252 808.0
TH1_k127_4248639_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 543.0
TH1_k127_4248639_2 Transcription termination factor nusG - - - 0.0000000000000000000000000000000000000000000000000002033 189.0
TH1_k127_4248639_3 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000002713 166.0
TH1_k127_4248639_4 - - - - 0.00000000000000000000000094 113.0
TH1_k127_4248639_5 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000005242 99.0
TH1_k127_4250077_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.262e-284 908.0
TH1_k127_4250077_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 514.0
TH1_k127_4250077_2 Chromate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 415.0
TH1_k127_4250077_3 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 281.0
TH1_k127_4250077_4 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000001905 203.0
TH1_k127_4250077_5 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000006769 180.0
TH1_k127_4250077_6 Rhodanese Homology Domain - - - 0.0000000000000000000009449 98.0
TH1_k127_4278675_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.218e-203 646.0
TH1_k127_4278675_1 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 504.0
TH1_k127_4278675_2 helix_turn_helix, cAMP Regulatory protein - - - 0.00000001641 62.0
TH1_k127_4279246_0 cell redox homeostasis - - - 3.284e-219 689.0
TH1_k127_4279246_1 PFAM Mannosyl oligosaccharide glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 338.0
TH1_k127_4279246_2 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 306.0
TH1_k127_4369036_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1516.0
TH1_k127_4369036_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.782e-268 840.0
TH1_k127_4369036_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000179 238.0
TH1_k127_4369036_11 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000003548 227.0
TH1_k127_4369036_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000004055 201.0
TH1_k127_4369036_13 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000006261 204.0
TH1_k127_4369036_14 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000007981 124.0
TH1_k127_4369036_15 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000000000000001415 86.0
TH1_k127_4369036_17 Regulatory protein, FmdB family - - - 0.000000000003094 68.0
TH1_k127_4369036_18 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000002615 62.0
TH1_k127_4369036_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 605.0
TH1_k127_4369036_3 Bacterial regulatory protein, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 388.0
TH1_k127_4369036_4 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 313.0
TH1_k127_4369036_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 301.0
TH1_k127_4369036_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 302.0
TH1_k127_4369036_7 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000001382 269.0
TH1_k127_4369036_8 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001067 263.0
TH1_k127_4369036_9 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000226 243.0
TH1_k127_4386972_0 FAD binding domain K00278 - 1.4.3.16 3.277e-195 623.0
TH1_k127_4386972_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 573.0
TH1_k127_4386972_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 305.0
TH1_k127_4386972_11 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 311.0
TH1_k127_4386972_12 Cytochrome b/b6/petB K03887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001945 276.0
TH1_k127_4386972_13 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000003555 253.0
TH1_k127_4386972_14 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000001335 214.0
TH1_k127_4386972_15 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000007593 205.0
TH1_k127_4386972_16 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000005149 177.0
TH1_k127_4386972_17 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000005552 158.0
TH1_k127_4386972_18 HAD-hyrolase-like - - - 0.00000000000000000000000000000003703 128.0
TH1_k127_4386972_19 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000001665 123.0
TH1_k127_4386972_2 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 522.0
TH1_k127_4386972_20 isomerase activity K01821 - 5.3.2.6 0.000000000000000000000000007012 113.0
TH1_k127_4386972_21 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000001119 115.0
TH1_k127_4386972_22 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000113 114.0
TH1_k127_4386972_23 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000007325 110.0
TH1_k127_4386972_24 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000006005 111.0
TH1_k127_4386972_25 Zinc finger cdgsh-type domain protein - - - 0.000000000000000000000002002 104.0
TH1_k127_4386972_27 LemA family K03744 - - 0.0003834 46.0
TH1_k127_4386972_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 495.0
TH1_k127_4386972_4 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 492.0
TH1_k127_4386972_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 472.0
TH1_k127_4386972_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 472.0
TH1_k127_4386972_7 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 426.0
TH1_k127_4386972_8 citrate synthase K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 400.0
TH1_k127_4386972_9 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 311.0
TH1_k127_4403786_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 531.0
TH1_k127_4403786_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000003968 244.0
TH1_k127_4403786_2 Protein of unknown function (DUF1385) - - - 0.00009202 45.0
TH1_k127_4597743_0 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 479.0
TH1_k127_4597743_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002545 287.0
TH1_k127_4598940_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1091.0
TH1_k127_4598940_1 PBP superfamily domain K03750,K07219 - 2.10.1.1 5.111e-252 793.0
TH1_k127_4598940_10 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 344.0
TH1_k127_4598940_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 337.0
TH1_k127_4598940_12 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 306.0
TH1_k127_4598940_13 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002376 270.0
TH1_k127_4598940_14 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000153 250.0
TH1_k127_4598940_15 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000001473 252.0
TH1_k127_4598940_16 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000001046 246.0
TH1_k127_4598940_17 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005898 237.0
TH1_k127_4598940_18 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004272 228.0
TH1_k127_4598940_19 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000001324 192.0
TH1_k127_4598940_2 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 614.0
TH1_k127_4598940_20 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000004226 192.0
TH1_k127_4598940_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000006641 187.0
TH1_k127_4598940_22 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000145 188.0
TH1_k127_4598940_23 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000009324 168.0
TH1_k127_4598940_24 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000007222 171.0
TH1_k127_4598940_25 ( 3 oxidation state) methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000001338 154.0
TH1_k127_4598940_26 Domains HisKA, HATPase_c - - - 0.0000000000000000000000000000000000001092 153.0
TH1_k127_4598940_27 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000004398 111.0
TH1_k127_4598940_28 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000002898 106.0
TH1_k127_4598940_29 - - - - 0.000000000000000000000009157 109.0
TH1_k127_4598940_3 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 453.0
TH1_k127_4598940_30 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000001467 97.0
TH1_k127_4598940_4 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 451.0
TH1_k127_4598940_5 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 449.0
TH1_k127_4598940_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 439.0
TH1_k127_4598940_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 421.0
TH1_k127_4598940_8 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 362.0
TH1_k127_4598940_9 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 344.0
TH1_k127_4658072_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1244.0
TH1_k127_4658072_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 421.0
TH1_k127_4658072_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004489 273.0
TH1_k127_4658072_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000001741 209.0
TH1_k127_4658072_4 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000000003155 201.0
TH1_k127_4658072_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000008155 149.0
TH1_k127_4658072_7 Sulfurtransferase TusA - - - 0.00000000000000000000009679 106.0
TH1_k127_4675350_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 554.0
TH1_k127_4675350_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 471.0
TH1_k127_4675350_2 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 428.0
TH1_k127_4675350_3 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 319.0
TH1_k127_4675350_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 301.0
TH1_k127_4675350_5 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009177 264.0
TH1_k127_4721449_0 response regulator receiver K02481,K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 371.0
TH1_k127_4721449_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007674 273.0
TH1_k127_4721449_2 HDOD domain - - - 0.0000000000000000000000000000000000000002441 157.0
TH1_k127_4880929_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 3.21e-303 943.0
TH1_k127_4880929_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 572.0
TH1_k127_4880929_10 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 336.0
TH1_k127_4880929_11 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 288.0
TH1_k127_4880929_12 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004728 274.0
TH1_k127_4880929_13 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 263.0
TH1_k127_4880929_14 Belongs to the sirtuin family. Class K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001817 267.0
TH1_k127_4880929_16 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001006 258.0
TH1_k127_4880929_17 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000005902 245.0
TH1_k127_4880929_18 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000007268 228.0
TH1_k127_4880929_19 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000004689 199.0
TH1_k127_4880929_2 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 523.0
TH1_k127_4880929_20 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000001426 191.0
TH1_k127_4880929_21 MarR family transcriptional K15973 - - 0.0000000000000000000000000000000000000000000002729 171.0
TH1_k127_4880929_22 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000002034 155.0
TH1_k127_4880929_23 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000001608 145.0
TH1_k127_4880929_24 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000001802 128.0
TH1_k127_4880929_25 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000001596 123.0
TH1_k127_4880929_26 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000008799 93.0
TH1_k127_4880929_28 PFAM Fimbrial assembly K02461 - - 0.000000000005315 79.0
TH1_k127_4880929_29 pilus assembly protein PilW K02459 - - 0.00000000001063 74.0
TH1_k127_4880929_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 467.0
TH1_k127_4880929_30 General secretion pathway protein M K02462 - - 0.000000005027 64.0
TH1_k127_4880929_31 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000002248 56.0
TH1_k127_4880929_32 COG4970 Tfp pilus assembly protein FimT K02457 - - 0.00000006083 61.0
TH1_k127_4880929_33 type IV pilus modification protein PilV K02458 - - 0.0000009389 61.0
TH1_k127_4880929_34 Universal stress protein family - - - 0.00007212 56.0
TH1_k127_4880929_35 Heavy-metal-associated domain K07213 - - 0.00008238 49.0
TH1_k127_4880929_36 general secretion pathway protein - - - 0.0002277 51.0
TH1_k127_4880929_37 - - - - 0.0005003 45.0
TH1_k127_4880929_5 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 420.0
TH1_k127_4880929_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 411.0
TH1_k127_4880929_7 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 394.0
TH1_k127_4880929_8 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 361.0
TH1_k127_4880929_9 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 347.0
TH1_k127_4886399_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 350.0
TH1_k127_4886399_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000002713 165.0
TH1_k127_4886399_2 Outer membrane efflux protein K15725 - - 0.0000000000000000000000001142 121.0
TH1_k127_4897819_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 5.787e-245 760.0
TH1_k127_4897819_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K05588 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 438.0
TH1_k127_4897819_2 PFAM NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000005412 263.0
TH1_k127_4897819_3 PFAM nickel-dependent hydrogenase, large subunit K00436 - 1.12.1.2 0.00000000000000000000000000000000000018 143.0
TH1_k127_4902718_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.416e-224 707.0
TH1_k127_4902718_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 307.0
TH1_k127_4902718_2 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005053 274.0
TH1_k127_4902718_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000006849 146.0
TH1_k127_4903138_0 HD domain K07023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 549.0
TH1_k127_4903138_1 metal ion transmembrane transporter activity K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 303.0
TH1_k127_4903138_2 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 301.0
TH1_k127_4903138_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001716 286.0
TH1_k127_4903138_5 translation initiation factor activity K08086,K20541 - - 0.0000000000000000000007635 109.0
TH1_k127_4903138_6 Protein of unknown function (DUF3108) - - - 0.000000000000000000001664 107.0
TH1_k127_4903138_7 coenzyme F420 binding K00275 - 1.4.3.5 0.0000000000003259 71.0
TH1_k127_4903138_8 - - - - 0.00000000007052 70.0
TH1_k127_4914674_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 468.0
TH1_k127_4914674_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006635 279.0
TH1_k127_4914674_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000004969 235.0
TH1_k127_4914674_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000371 83.0
TH1_k127_4914674_4 deoxyhypusine monooxygenase activity - - - 0.000000000001553 77.0
TH1_k127_4914674_5 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00001217 53.0
TH1_k127_4954589_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.627e-264 850.0
TH1_k127_4954589_1 Highly conserved protein containing a thioredoxin domain K06888 - - 1.61e-237 751.0
TH1_k127_4954589_10 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000381 265.0
TH1_k127_4954589_11 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000002862 181.0
TH1_k127_4954589_12 cyclic nucleotide binding K01420,K10716 - - 0.0000000000000000000000000000000000000000000309 169.0
TH1_k127_4954589_13 domain protein - - - 0.00000000000000000000000000000003054 147.0
TH1_k127_4954589_14 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000003375 114.0
TH1_k127_4954589_15 Subtilase family - - - 0.0000000000000000000001185 115.0
TH1_k127_4954589_16 Metallo-peptidase family M12 - - - 0.0000000000000000000004997 100.0
TH1_k127_4954589_17 TPR repeat - - - 0.0000000000000000003683 97.0
TH1_k127_4954589_18 cellulase activity K12287 - - 0.0000000000000009895 89.0
TH1_k127_4954589_19 S-layer homology domain - - - 0.000000002116 69.0
TH1_k127_4954589_2 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 575.0
TH1_k127_4954589_21 - - - - 0.000005466 49.0
TH1_k127_4954589_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 492.0
TH1_k127_4954589_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 420.0
TH1_k127_4954589_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 409.0
TH1_k127_4954589_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 378.0
TH1_k127_4954589_7 sugar transferase K00996 - 2.7.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 366.0
TH1_k127_4954589_8 PFAM Glycosyl transferase family 2 K12992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 309.0
TH1_k127_4954589_9 RmlD substrate binding domain K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 277.0
TH1_k127_4960103_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 579.0
TH1_k127_4960103_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003663 241.0
TH1_k127_4960103_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000002537 218.0
TH1_k127_4960103_3 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000001368 210.0
TH1_k127_4974947_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 513.0
TH1_k127_4974947_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 406.0
TH1_k127_4974947_10 Peptidase family M23 - - - 0.00000000000000000000000000000000000883 148.0
TH1_k127_4974947_11 PFAM FlhB HrpN YscU SpaS Family K04061 - - 0.0000000000000000000000126 102.0
TH1_k127_4974947_12 flagella basal body P-ring formation protein FlgA K02386 - - 0.000000000000000000031 98.0
TH1_k127_4974947_13 Belongs to the bacterial flagellin family K02397 - - 0.000000000563 70.0
TH1_k127_4974947_14 - - - - 0.00000000799 68.0
TH1_k127_4974947_16 COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) K02398 - - 0.000001894 53.0
TH1_k127_4974947_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 359.0
TH1_k127_4974947_3 flagellar basal-body rod protein FlgG K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 347.0
TH1_k127_4974947_4 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 306.0
TH1_k127_4974947_5 TIGRFAM flagellar hook-associated protein FlgK K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000235 272.0
TH1_k127_4974947_6 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000001746 220.0
TH1_k127_4974947_7 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000002177 222.0
TH1_k127_4974947_8 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000003811 220.0
TH1_k127_4974947_9 PFAM flagellar basal body rod protein K02392 - - 0.0000000000000000000000000000000000000004258 161.0
TH1_k127_4976637_0 40-residue yvtn family beta-propeller repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 551.0
TH1_k127_4976637_1 PFAM Stage II sporulation E family protein - - - 0.000000000000000000000000000001538 124.0
TH1_k127_4980189_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.25e-317 977.0
TH1_k127_4980189_1 FMN binding - - - 5.08e-276 855.0
TH1_k127_4980189_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 478.0
TH1_k127_4980189_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 389.0
TH1_k127_4980189_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 378.0
TH1_k127_4980189_5 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 309.0
TH1_k127_4994509_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367,K02567 - 1.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 577.0
TH1_k127_4994509_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 391.0
TH1_k127_4994509_2 Ferredoxin-type protein, NapH MauN family K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 333.0
TH1_k127_4994509_3 TIGRFAM MauM NapG family ferredoxin-type protein K02573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 321.0
TH1_k127_4994509_4 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000005179 177.0
TH1_k127_4994509_5 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.0000000000000000000000000000000000000001129 157.0
TH1_k127_4994509_6 negative regulation of establishment of protein localization K02570 GO:0003674,GO:0005048,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032879,GO:0032880,GO:0033218,GO:0042277,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0051049,GO:0051051,GO:0051223,GO:0051224,GO:0065007,GO:0070201,GO:0090087,GO:1904950 - 0.0000000000000000001125 91.0
TH1_k127_500466_0 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 576.0
TH1_k127_500466_1 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001961 198.0
TH1_k127_500466_2 Protein of unknown function (DUF2934) - - - 0.00000005396 57.0
TH1_k127_500466_3 electron transfer activity K00428 - 1.11.1.5 0.000002063 53.0
TH1_k127_5006041_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.233e-268 834.0
TH1_k127_5006041_1 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 514.0
TH1_k127_5006041_10 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
TH1_k127_5006041_11 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002562 247.0
TH1_k127_5006041_12 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000000000000000000000002992 222.0
TH1_k127_5006041_13 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001255 229.0
TH1_k127_5006041_14 PFAM flagellar FlbT family protein K06601 - - 0.00000000000000000000000000000000000000000000000008951 180.0
TH1_k127_5006041_15 Bacterial regulatory proteins, crp family - - - 0.000000000000000000000000000000000000000000005017 169.0
TH1_k127_5006041_17 diguanylate cyclase - - - 0.000000000000000000000000002603 118.0
TH1_k127_5006041_18 Flagellar protein FlaF K06602 - - 0.000000000000000000000009697 106.0
TH1_k127_5006041_19 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000001152 96.0
TH1_k127_5006041_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 484.0
TH1_k127_5006041_20 PilZ domain - - - 0.000000000000000004752 94.0
TH1_k127_5006041_21 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000001529 83.0
TH1_k127_5006041_22 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000005063 81.0
TH1_k127_5006041_23 PilZ domain - - - 0.000000000005369 71.0
TH1_k127_5006041_24 - - - - 0.0000139 57.0
TH1_k127_5006041_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 469.0
TH1_k127_5006041_4 Bacterial regulatory protein, Fis family K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 442.0
TH1_k127_5006041_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 426.0
TH1_k127_5006041_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 324.0
TH1_k127_5006041_7 PFAM flagellin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 319.0
TH1_k127_5006041_8 PFAM Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 311.0
TH1_k127_5006041_9 archaeal or bacterial-type flagellum-dependent cell motility K02556 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 309.0
TH1_k127_5018739_0 Ftsk_gamma K03466 - - 3.25e-207 672.0
TH1_k127_5018739_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.692e-202 643.0
TH1_k127_5018739_10 NOG31153 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000009781 239.0
TH1_k127_5018739_11 translation initiation factor activity K03699 - - 0.000000000000000000000000000000000000000000000000000000000000001967 231.0
TH1_k127_5018739_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000003784 83.0
TH1_k127_5018739_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 4.788e-200 637.0
TH1_k127_5018739_3 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 573.0
TH1_k127_5018739_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 559.0
TH1_k127_5018739_5 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 492.0
TH1_k127_5018739_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 387.0
TH1_k127_5018739_7 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 364.0
TH1_k127_5018739_8 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 301.0
TH1_k127_5018739_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000005187 260.0
TH1_k127_5020257_0 Sigma-54 interaction domain K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 415.0
TH1_k127_5020257_1 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000001794 207.0
TH1_k127_5020257_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000002191 167.0
TH1_k127_5020257_3 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000000271 91.0
TH1_k127_5020257_4 Sugar (and other) transporter K03446 - - 0.000000000000000004837 86.0
TH1_k127_5025448_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 596.0
TH1_k127_5025448_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 535.0
TH1_k127_5025448_10 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000001857 136.0
TH1_k127_5025448_11 Cytochrome c - - - 0.000000000000000000000000004264 121.0
TH1_k127_5025448_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000001042 104.0
TH1_k127_5025448_2 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 420.0
TH1_k127_5025448_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 359.0
TH1_k127_5025448_4 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 316.0
TH1_k127_5025448_5 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 306.0
TH1_k127_5025448_6 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007882 245.0
TH1_k127_5025448_7 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000713 215.0
TH1_k127_5025448_8 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000001247 189.0
TH1_k127_5025448_9 metal cluster binding K06940,K18475 - - 0.00000000000000000000000000000000003637 146.0
TH1_k127_5061616_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1056.0
TH1_k127_5061616_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 526.0
TH1_k127_5061616_2 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000006271 189.0
TH1_k127_5081008_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1039.0
TH1_k127_5081008_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.727e-320 999.0
TH1_k127_5081008_10 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 508.0
TH1_k127_5081008_11 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 459.0
TH1_k127_5081008_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 443.0
TH1_k127_5081008_13 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 430.0
TH1_k127_5081008_14 Dehydrogenase E1 component K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 410.0
TH1_k127_5081008_15 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 375.0
TH1_k127_5081008_16 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 357.0
TH1_k127_5081008_17 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 359.0
TH1_k127_5081008_18 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 291.0
TH1_k127_5081008_19 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001447 271.0
TH1_k127_5081008_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.006e-295 915.0
TH1_k127_5081008_20 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002572 247.0
TH1_k127_5081008_21 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000001218 239.0
TH1_k127_5081008_22 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000002943 238.0
TH1_k127_5081008_23 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000001115 217.0
TH1_k127_5081008_24 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000003183 213.0
TH1_k127_5081008_25 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000007913 209.0
TH1_k127_5081008_26 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000001215 200.0
TH1_k127_5081008_27 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000006156 189.0
TH1_k127_5081008_28 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.000000000000000000000000000000000000000006658 163.0
TH1_k127_5081008_29 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000004394 165.0
TH1_k127_5081008_3 5TM C-terminal transporter carbon starvation CstA K06200 - - 4.352e-275 859.0
TH1_k127_5081008_30 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000000001777 158.0
TH1_k127_5081008_31 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000004296 147.0
TH1_k127_5081008_32 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000000000000000000000171 139.0
TH1_k127_5081008_33 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000001006 130.0
TH1_k127_5081008_34 RDD family - - - 0.00000000000000000000000000001806 122.0
TH1_k127_5081008_35 Type II secretion system protein B K02451 - - 0.0000000000000000007476 99.0
TH1_k127_5081008_36 Mrr N-terminal domain K07448 - - 0.00000000006714 64.0
TH1_k127_5081008_37 - - - - 0.000000001856 61.0
TH1_k127_5081008_4 Surface antigen K07277 - - 8.679e-260 852.0
TH1_k127_5081008_5 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 587.0
TH1_k127_5081008_6 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 558.0
TH1_k127_5081008_7 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 530.0
TH1_k127_5081008_8 purine nucleobase transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 525.0
TH1_k127_5081008_9 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 523.0
TH1_k127_5146981_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 456.0
TH1_k127_5146981_1 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 409.0
TH1_k127_5146981_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000001786 190.0
TH1_k127_5146981_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000008881 133.0
TH1_k127_5147166_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 9.139e-200 628.0
TH1_k127_5147166_1 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 438.0
TH1_k127_5147166_2 CAAX protease self-immunity K07052 - - 0.0000000001797 69.0
TH1_k127_5190185_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 343.0
TH1_k127_5190185_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 333.0
TH1_k127_5190185_3 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000883 205.0
TH1_k127_5190185_5 protein secretion K03116,K03117 - - 0.000000000000007811 79.0
TH1_k127_5218539_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 9.027e-218 695.0
TH1_k127_5218539_1 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 471.0
TH1_k127_5218539_2 PFAM CBS domain containing protein K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 299.0
TH1_k127_523110_0 Glycosyl hydrolase family 57 - - - 3.487e-208 652.0
TH1_k127_523110_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008504 277.0
TH1_k127_523110_2 Haemolytic - - - 0.000000000000000000000001942 108.0
TH1_k127_5233766_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.728e-298 925.0
TH1_k127_5233766_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 3.842e-222 698.0
TH1_k127_5233766_2 B3/4 domain K01890 - 6.1.1.20 4.092e-204 656.0
TH1_k127_5233766_3 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 491.0
TH1_k127_5233766_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 458.0
TH1_k127_5233766_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002657 248.0
TH1_k127_5233766_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000165 178.0
TH1_k127_5233766_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000001153 160.0
TH1_k127_5233766_8 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000492 93.0
TH1_k127_5233766_9 TIGRFAM Addiction module killer protein - - - 0.000000000000000004149 85.0
TH1_k127_52662_0 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 409.0
TH1_k127_52662_1 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000001184 134.0
TH1_k127_52662_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000004397 92.0
TH1_k127_52662_3 Subtilase family - - - 0.00000000000000486 88.0
TH1_k127_52662_4 S-layer homology domain - - - 0.00000007044 56.0
TH1_k127_5274997_0 citrate synthase K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 403.0
TH1_k127_5274997_1 NosL - - - 0.000000000000000000000000000000000000000008459 160.0
TH1_k127_5274997_2 PFAM Pyridoxamine 5'-phosphate - - - 0.0000000000000001495 81.0
TH1_k127_5282326_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.157e-243 758.0
TH1_k127_5282326_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.501e-235 737.0
TH1_k127_5282326_10 SCO1 SenC K07152 - - 0.00000005626 54.0
TH1_k127_5282326_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.229e-224 713.0
TH1_k127_5282326_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 513.0
TH1_k127_5282326_4 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 331.0
TH1_k127_5282326_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000005884 244.0
TH1_k127_5282326_6 group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000001741 221.0
TH1_k127_5282326_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000008589 224.0
TH1_k127_5282326_8 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000006112 116.0
TH1_k127_5282326_9 Uncharacterized conserved protein (DUF2304) - - - 0.000000007846 63.0
TH1_k127_5290676_0 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 610.0
TH1_k127_5290676_1 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 295.0
TH1_k127_5290676_2 radical SAM protein K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001392 278.0
TH1_k127_5302244_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 359.0
TH1_k127_5302244_1 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000005853 235.0
TH1_k127_5302244_2 RelE-like toxin of type II toxin-antitoxin system HigB K07334 GO:0008150,GO:0008219,GO:0009987 - 0.0000000000000000000000000007666 115.0
TH1_k127_5302244_3 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000001653 114.0
TH1_k127_5302244_4 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000006282 75.0
TH1_k127_5310598_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 5.638e-263 828.0
TH1_k127_5310598_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.923e-226 715.0
TH1_k127_5310598_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005527 249.0
TH1_k127_5310598_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000003404 218.0
TH1_k127_5310598_12 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000001699 211.0
TH1_k127_5310598_13 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000002854 189.0
TH1_k127_5310598_14 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000000000001953 169.0
TH1_k127_5310598_15 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000000000000000000001042 161.0
TH1_k127_5310598_16 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000008259 168.0
TH1_k127_5310598_17 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000008112 153.0
TH1_k127_5310598_19 GAF domain K07678,K07716 - 2.7.13.3 0.000000000000000000000000000000000003287 144.0
TH1_k127_5310598_2 4Fe-4S binding domain - - - 2.936e-219 690.0
TH1_k127_5310598_20 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000001919 115.0
TH1_k127_5310598_21 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000000000000009641 111.0
TH1_k127_5310598_22 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.0000000000000000000003955 98.0
TH1_k127_5310598_24 Histidine Phosphotransfer domain - - - 0.0000000000272 68.0
TH1_k127_5310598_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 561.0
TH1_k127_5310598_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 463.0
TH1_k127_5310598_5 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 404.0
TH1_k127_5310598_6 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 383.0
TH1_k127_5310598_7 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 303.0
TH1_k127_5310598_8 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 284.0
TH1_k127_5310598_9 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001733 275.0
TH1_k127_5316049_0 FMN binding - - - 1.416e-274 851.0
TH1_k127_5316049_1 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 584.0
TH1_k127_5316049_2 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 389.0
TH1_k127_5316049_3 Domain of unknown function (DUF1848) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 351.0
TH1_k127_5316049_4 Nitrogen regulatory protein P-II K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000002828 177.0
TH1_k127_5316049_5 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000001159 101.0
TH1_k127_5318462_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 396.0
TH1_k127_5318462_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 357.0
TH1_k127_5318462_2 - - - - 0.000000000000000000000002655 102.0
TH1_k127_5356474_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 497.0
TH1_k127_5356474_1 Domain of unknown function (DUF3413) K07014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 389.0
TH1_k127_5356474_10 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000005518 222.0
TH1_k127_5356474_11 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000007584 218.0
TH1_k127_5356474_12 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000002059 195.0
TH1_k127_5356474_13 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000002835 195.0
TH1_k127_5356474_14 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000001581 153.0
TH1_k127_5356474_15 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.0000000000000000000000000000000000000009412 160.0
TH1_k127_5356474_16 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000148 131.0
TH1_k127_5356474_17 protein with SCP PR1 domains - - - 0.000000000000000001581 93.0
TH1_k127_5356474_18 COG3307 Lipid A core - O-antigen ligase and related enzymes K02847 - - 0.00003043 56.0
TH1_k127_5356474_2 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 363.0
TH1_k127_5356474_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 314.0
TH1_k127_5356474_4 biosynthesis glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 298.0
TH1_k127_5356474_5 PFAM glycosyl transferase, family 9 K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 295.0
TH1_k127_5356474_6 transferase activity, transferring glycosyl groups K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000122 291.0
TH1_k127_5356474_7 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 277.0
TH1_k127_5356474_8 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000006287 225.0
TH1_k127_5356474_9 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000002599 224.0
TH1_k127_5387688_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 355.0
TH1_k127_5387688_1 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000008906 100.0
TH1_k127_5445543_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 532.0
TH1_k127_5445543_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 301.0
TH1_k127_5445543_2 Protein of unknown function (DUF1460) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004869 258.0
TH1_k127_5445543_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000009548 213.0
TH1_k127_5445543_4 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000006693 184.0
TH1_k127_5445543_5 DNA polymerase Ligase (LigD) - - - 0.0000000000000000000000000000000000000000000000001036 184.0
TH1_k127_5445543_6 Thioredoxin-like - - - 0.000000000000000000000000000000001341 136.0
TH1_k127_5445543_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000007458 110.0
TH1_k127_5445543_8 Protein of unknown function (DUF2845) - - - 0.00000000000000001521 88.0
TH1_k127_5445543_9 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0001985 54.0
TH1_k127_5543261_0 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 532.0
TH1_k127_5543261_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 503.0
TH1_k127_5543261_2 phosphorelay sensor kinase activity K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 428.0
TH1_k127_5543261_3 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000000006762 142.0
TH1_k127_5543261_4 Trypsin-like peptidase domain - - - 0.0000000000000000000000004069 119.0
TH1_k127_5543261_5 peptidyl-tyrosine sulfation - - - 0.000000002167 69.0
TH1_k127_5620768_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.281e-258 818.0
TH1_k127_5620768_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.772e-195 617.0
TH1_k127_5620768_10 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000009526 110.0
TH1_k127_5620768_12 Abc transporter K02006 - - 0.000000000001189 70.0
TH1_k127_5620768_13 - - - - 0.0000004377 55.0
TH1_k127_5620768_2 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 572.0
TH1_k127_5620768_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 456.0
TH1_k127_5620768_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 346.0
TH1_k127_5620768_5 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 346.0
TH1_k127_5620768_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 330.0
TH1_k127_5620768_7 Thymidylate synthase complementing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 317.0
TH1_k127_5620768_8 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 312.0
TH1_k127_5620768_9 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00000000000000000000000000000000001586 150.0
TH1_k127_5671068_0 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 336.0
TH1_k127_5671068_1 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 297.0
TH1_k127_5671068_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000262 124.0
TH1_k127_5748712_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 6.696e-219 690.0
TH1_k127_5748712_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 3.941e-218 685.0
TH1_k127_5748712_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 499.0
TH1_k127_5748712_3 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 332.0
TH1_k127_5748712_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001919 257.0
TH1_k127_5748712_5 LysM domain - - - 0.00000000000000000000000000000004488 138.0
TH1_k127_5789325_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 619.0
TH1_k127_5789325_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 484.0
TH1_k127_5789325_2 PFAM PfkB K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 390.0
TH1_k127_5789325_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 296.0
TH1_k127_5789325_4 epimerase dehydratase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000667 288.0
TH1_k127_5789325_5 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002182 278.0
TH1_k127_5789325_6 - - - - 0.00000000000000000000000000000000000000001118 158.0
TH1_k127_5789325_7 membrane transporter protein K07090 - - 0.00000000000000008761 80.0
TH1_k127_5814947_0 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 357.0
TH1_k127_5814947_1 Major Facilitator Superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000009562 102.0
TH1_k127_5814947_2 Dihaem cytochrome c - - - 0.000000000000002609 80.0
TH1_k127_5909619_0 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 407.0
TH1_k127_5909619_1 smart pdz dhr glgf - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009772 290.0
TH1_k127_5909619_2 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000005447 92.0
TH1_k127_6011917_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 381.0
TH1_k127_6011917_1 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000003242 143.0
TH1_k127_6011917_2 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000002098 89.0
TH1_k127_6058621_0 Aminotransferase K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 507.0
TH1_k127_6058621_1 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 393.0
TH1_k127_6058621_2 lytic transglycosylase K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000381 243.0
TH1_k127_6058621_3 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000001046 175.0
TH1_k127_6058621_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03774,K03775 - 5.2.1.8 0.0000000000000000000000000000000003818 138.0
TH1_k127_6058621_5 Membrane - - - 0.000000000000000000000000000000002097 133.0
TH1_k127_6058621_6 PFAM pyridoxamine 5-phosphate - - - 0.000000000000000000001513 96.0
TH1_k127_6058621_7 Transcriptional regulator, LysR - - - 0.000000000000000003704 96.0
TH1_k127_6087228_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1424.0
TH1_k127_6087228_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000986 464.0
TH1_k127_6087228_10 Membrane - - - 0.000000000000000000002689 99.0
TH1_k127_6087228_11 Translation initiation factor SUI1 K03113 - - 0.00000000000000000001015 99.0
TH1_k127_6087228_12 Protein of unknown function (DUF2892) - - - 0.00000000000000000006223 93.0
TH1_k127_6087228_13 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000001998 80.0
TH1_k127_6087228_2 PFAM tRNA pseudouridine synthase D TruD K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 396.0
TH1_k127_6087228_3 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 383.0
TH1_k127_6087228_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 354.0
TH1_k127_6087228_5 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 288.0
TH1_k127_6087228_6 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002143 280.0
TH1_k127_6087228_7 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005866 259.0
TH1_k127_6087228_8 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003876 263.0
TH1_k127_6087228_9 - - - - 0.00000000000000000000000000003076 120.0
TH1_k127_608975_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 516.0
TH1_k127_608975_1 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 444.0
TH1_k127_608975_2 proline dipeptidase activity K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 334.0
TH1_k127_608975_3 Pyruvate phosphate dikinase, PEP K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 357.0
TH1_k127_608975_4 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 311.0
TH1_k127_608975_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 310.0
TH1_k127_608975_6 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000001643 118.0
TH1_k127_608975_7 HDOD domain - - - 0.000000000000000005895 87.0
TH1_k127_6112399_0 4Fe-4S dicluster domain - - - 1.098e-236 735.0
TH1_k127_6112399_1 - - - - 0.00000000000000000000000000000000000000000004115 164.0
TH1_k127_6124558_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 6.564e-229 719.0
TH1_k127_6124558_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 3.404e-204 653.0
TH1_k127_6124558_10 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 304.0
TH1_k127_6124558_11 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 300.0
TH1_k127_6124558_12 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 299.0
TH1_k127_6124558_13 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004408 270.0
TH1_k127_6124558_14 Belongs to the acetokinase family K00929 - 2.7.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000153 268.0
TH1_k127_6124558_15 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000006236 231.0
TH1_k127_6124558_16 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000001095 204.0
TH1_k127_6124558_17 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000000009078 173.0
TH1_k127_6124558_18 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000000001808 150.0
TH1_k127_6124558_19 PFAM Ankyrin K21440 - - 0.00000000000000000000000000004243 128.0
TH1_k127_6124558_2 TIGRFAM oligoendopeptidase, pepF M3 family K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 612.0
TH1_k127_6124558_20 - - - - 0.00000000000000000000000001379 120.0
TH1_k127_6124558_21 domain, Protein - - - 0.000001197 60.0
TH1_k127_6124558_22 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000415 51.0
TH1_k127_6124558_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 520.0
TH1_k127_6124558_4 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 497.0
TH1_k127_6124558_5 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 486.0
TH1_k127_6124558_6 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 405.0
TH1_k127_6124558_7 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 397.0
TH1_k127_6124558_8 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 316.0
TH1_k127_6124558_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 319.0
TH1_k127_6162068_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 3.885e-253 786.0
TH1_k127_6162068_1 UPF0210 protein K09157 - - 2.101e-218 686.0
TH1_k127_6162068_10 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.000000000000001168 80.0
TH1_k127_6162068_12 FixH - - - 0.0000002926 61.0
TH1_k127_6162068_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 492.0
TH1_k127_6162068_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 351.0
TH1_k127_6162068_4 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 337.0
TH1_k127_6162068_5 PFAM amino acid-binding ACT domain protein K03567 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001271 258.0
TH1_k127_6162068_6 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000004425 161.0
TH1_k127_6162068_7 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000006173 133.0
TH1_k127_6162068_8 Dodecin K09165 - - 0.0000000000000000001857 90.0
TH1_k127_6162068_9 FixH - - - 0.00000000000000007426 91.0
TH1_k127_6198323_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 538.0
TH1_k127_6198323_1 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 452.0
TH1_k127_6198323_2 PFAM Amidohydrolase 2 K01686 - 4.2.1.8 0.000000000000000000000002117 115.0
TH1_k127_6198323_3 phosphorelay signal transduction system - - - 0.00000000005041 63.0
TH1_k127_6198323_4 Belongs to the thioredoxin family K03671 - - 0.00000001723 58.0
TH1_k127_6198323_5 Thioredoxin K03672 - 1.8.1.8 0.00000006976 58.0
TH1_k127_6200911_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 8.888e-222 695.0
TH1_k127_6200911_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 385.0
TH1_k127_6200911_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000005276 173.0
TH1_k127_6200911_3 COG0569 K transport systems NAD-binding component K11105 - - 0.0000000002422 65.0
TH1_k127_6286195_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1130.0
TH1_k127_6286195_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 533.0
TH1_k127_6286195_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000149 79.0
TH1_k127_6286195_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 491.0
TH1_k127_6286195_3 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 291.0
TH1_k127_6286195_4 COG0644 Dehydrogenases (flavoproteins) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001958 259.0
TH1_k127_6286195_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000003145 243.0
TH1_k127_6286195_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001029 218.0
TH1_k127_6286195_7 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000006328 207.0
TH1_k127_6286195_8 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000135 167.0
TH1_k127_6286195_9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000001223 123.0
TH1_k127_6294662_0 cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 368.0
TH1_k127_6294662_1 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 271.0
TH1_k127_6294662_2 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000002207 145.0
TH1_k127_6294662_3 - - - - 0.00000000000000000000000004523 123.0
TH1_k127_6305813_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 424.0
TH1_k127_6305813_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 407.0
TH1_k127_6305813_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 326.0
TH1_k127_6305813_3 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 310.0
TH1_k127_6305813_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 259.0
TH1_k127_6305813_5 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000002671 220.0
TH1_k127_6313244_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.578e-229 721.0
TH1_k127_6313244_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 288.0
TH1_k127_6313244_2 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000003186 217.0
TH1_k127_6313244_3 ATPases associated with a variety of cellular activities K01990,K11050 - - 0.000000000000000000000000000000000005733 138.0
TH1_k127_6313244_4 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000002868 132.0
TH1_k127_6313244_5 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000002254 95.0
TH1_k127_6321717_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 359.0
TH1_k127_6321717_1 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000002374 267.0
TH1_k127_6321717_2 Protein conserved in bacteria K07011 - - 0.0000000000000000000000000000000000000000000000000005705 191.0
TH1_k127_6340723_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 425.0
TH1_k127_6340723_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 402.0
TH1_k127_6340723_2 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 353.0
TH1_k127_6340723_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000007645 129.0
TH1_k127_6340723_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000006098 122.0
TH1_k127_635995_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 527.0
TH1_k127_635995_1 gas vesicle protein - - - 0.00000000000000000001075 96.0
TH1_k127_635995_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000001089 74.0
TH1_k127_636014_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 511.0
TH1_k127_636014_1 gas vesicle protein - - - 0.00000000000000000002763 95.0
TH1_k127_636014_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000001089 74.0
TH1_k127_6407741_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 513.0
TH1_k127_6407741_1 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005787 247.0
TH1_k127_6407741_2 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000005599 193.0
TH1_k127_6414530_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 548.0
TH1_k127_6542290_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 4.678e-222 708.0
TH1_k127_6542290_1 Cellulose biosynthesis protein BcsQ K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009419 282.0
TH1_k127_6542290_10 Flagellar biosynthetic protein FliQ K02420 - - 0.000000000000000114 90.0
TH1_k127_6542290_2 FliP family K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001185 254.0
TH1_k127_6542290_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007565 254.0
TH1_k127_6542290_4 flagellar motor switch protein FliM K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009998 255.0
TH1_k127_6542290_5 sigma factor activity K02405,K03093 - - 0.00000000000000000000000000000000000000000000000001739 195.0
TH1_k127_6542290_6 GTP-binding signal recognition particle SRP54 K02404 - - 0.000000000000000000000000000000000000000000000005389 186.0
TH1_k127_6542290_7 PFAM surface presentation of antigens (SPOA) protein K02417 - - 0.0000000000000000000000000000000000002585 143.0
TH1_k127_6542290_8 Role in flagellar biosynthesis K02421 - - 0.00000000000000000000000000000000106 139.0
TH1_k127_6542290_9 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000001768 88.0
TH1_k127_6638325_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 444.0
TH1_k127_6638325_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 336.0
TH1_k127_6638325_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000008854 228.0
TH1_k127_6638325_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000089 218.0
TH1_k127_6638325_4 TIGRFAM polysaccharide pyruvyl transferase CsaB - - - 0.00000000000000000000000000000007367 139.0
TH1_k127_6638325_5 Metallo-peptidase family M12 - - - 0.000000000000000000000003705 121.0
TH1_k127_6638325_6 Parallel beta-helix repeats - - - 0.000000000000005155 78.0
TH1_k127_6638325_7 COG4124 Beta-mannanase - - - 0.00000000000446 81.0
TH1_k127_6638325_8 6-phosphogluconolactonase activity - - - 0.000002432 62.0
TH1_k127_6828710_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1242.0
TH1_k127_6828710_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 463.0
TH1_k127_6828710_10 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000001425 86.0
TH1_k127_6828710_2 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 419.0
TH1_k127_6828710_3 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 403.0
TH1_k127_6828710_4 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 407.0
TH1_k127_6828710_5 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 345.0
TH1_k127_6828710_6 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001956 282.0
TH1_k127_6828710_7 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000005845 220.0
TH1_k127_6828710_8 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000001848 200.0
TH1_k127_6828710_9 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000000000000002338 97.0
TH1_k127_6831167_0 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000000000000000007049 189.0
TH1_k127_6831167_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000325 59.0
TH1_k127_6833246_0 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 518.0
TH1_k127_6833246_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000008332 160.0
TH1_k127_6833246_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000001883 117.0
TH1_k127_7052854_0 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001354 250.0
TH1_k127_7052854_1 COGs COG1639 signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000001894 233.0
TH1_k127_7052854_2 C-terminal, D2-small domain, of ClpB protein K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0000000000000003199 93.0
TH1_k127_7052854_3 Sigma54 specific transcriptional regulator, Fis family K21405 - - 0.0000002321 64.0
TH1_k127_707585_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 6.686e-245 769.0
TH1_k127_707585_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.366e-242 760.0
TH1_k127_707585_10 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000003428 162.0
TH1_k127_707585_12 - - - - 0.00000002017 64.0
TH1_k127_707585_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 565.0
TH1_k127_707585_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 512.0
TH1_k127_707585_4 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 522.0
TH1_k127_707585_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 397.0
TH1_k127_707585_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 361.0
TH1_k127_707585_7 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 332.0
TH1_k127_707585_8 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 313.0
TH1_k127_707585_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000572 251.0
TH1_k127_7117556_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1097.0
TH1_k127_7117556_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 1.356e-199 642.0
TH1_k127_7117556_10 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 296.0
TH1_k127_7117556_11 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000008893 204.0
TH1_k127_7117556_12 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000004141 166.0
TH1_k127_7117556_13 Putative regulatory protein - - - 0.00000000000000000000001799 103.0
TH1_k127_7117556_14 Rubrerythrin - - - 0.00000000000000000004139 96.0
TH1_k127_7117556_2 ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 572.0
TH1_k127_7117556_3 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 499.0
TH1_k127_7117556_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 463.0
TH1_k127_7117556_5 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 454.0
TH1_k127_7117556_6 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 440.0
TH1_k127_7117556_7 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 365.0
TH1_k127_7117556_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 316.0
TH1_k127_7117556_9 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 313.0
TH1_k127_7118011_0 Protein of unknown function (DUF2867) - - - 6.942e-195 624.0
TH1_k127_7118011_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 564.0
TH1_k127_7118011_10 - - - - 0.00000000000000000000000000000000000004351 152.0
TH1_k127_7118011_11 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000002227 136.0
TH1_k127_7118011_12 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000005069 129.0
TH1_k127_7118011_13 - - - - 0.0000000000000000000002663 101.0
TH1_k127_7118011_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000002101 93.0
TH1_k127_7118011_15 - - - - 0.0000000000002005 78.0
TH1_k127_7118011_16 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000002042 64.0
TH1_k127_7118011_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 456.0
TH1_k127_7118011_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 340.0
TH1_k127_7118011_4 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 334.0
TH1_k127_7118011_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 325.0
TH1_k127_7118011_6 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001624 270.0
TH1_k127_7118011_7 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002632 241.0
TH1_k127_7118011_8 - - - - 0.000000000000000000000000000000000000000000000000000000002577 206.0
TH1_k127_7118011_9 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000004094 161.0
TH1_k127_713503_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1133.0
TH1_k127_713503_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.943e-222 696.0
TH1_k127_713503_10 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000005107 226.0
TH1_k127_713503_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000005077 221.0
TH1_k127_713503_12 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000455 205.0
TH1_k127_713503_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 571.0
TH1_k127_713503_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 544.0
TH1_k127_713503_4 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 557.0
TH1_k127_713503_5 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 455.0
TH1_k127_713503_6 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 346.0
TH1_k127_713503_7 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 341.0
TH1_k127_713503_8 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 334.0
TH1_k127_713503_9 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003831 284.0
TH1_k127_714656_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 0.0 1163.0
TH1_k127_714656_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 489.0
TH1_k127_714656_2 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 406.0
TH1_k127_714656_3 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 398.0
TH1_k127_714656_4 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000008106 241.0
TH1_k127_714656_5 Belongs to the helicase family. UvrD subfamily K03657 - 3.6.4.12 0.000449 46.0
TH1_k127_7328304_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 3.067e-320 995.0
TH1_k127_7328304_1 nodulation K00612 - - 3.737e-289 898.0
TH1_k127_7328304_10 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 470.0
TH1_k127_7328304_11 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 449.0
TH1_k127_7328304_12 PFAM Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 445.0
TH1_k127_7328304_13 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 432.0
TH1_k127_7328304_14 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 402.0
TH1_k127_7328304_15 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 401.0
TH1_k127_7328304_16 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 394.0
TH1_k127_7328304_17 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 392.0
TH1_k127_7328304_18 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 379.0
TH1_k127_7328304_19 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 356.0
TH1_k127_7328304_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 5.878e-288 896.0
TH1_k127_7328304_20 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 362.0
TH1_k127_7328304_21 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 344.0
TH1_k127_7328304_22 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 366.0
TH1_k127_7328304_23 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 330.0
TH1_k127_7328304_24 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 320.0
TH1_k127_7328304_25 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 317.0
TH1_k127_7328304_26 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 318.0
TH1_k127_7328304_27 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 305.0
TH1_k127_7328304_28 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 302.0
TH1_k127_7328304_29 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 299.0
TH1_k127_7328304_3 Elongation factor SelB, winged helix K03833 - - 6.556e-219 702.0
TH1_k127_7328304_30 Precorrin-4 C(11)-methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 291.0
TH1_k127_7328304_31 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003454 293.0
TH1_k127_7328304_32 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001948 284.0
TH1_k127_7328304_33 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004423 274.0
TH1_k127_7328304_34 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004653 267.0
TH1_k127_7328304_35 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 258.0
TH1_k127_7328304_36 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002002 267.0
TH1_k127_7328304_37 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000014 261.0
TH1_k127_7328304_38 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000004407 256.0
TH1_k127_7328304_39 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000007834 250.0
TH1_k127_7328304_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 552.0
TH1_k127_7328304_40 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000007356 242.0
TH1_k127_7328304_41 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000001106 231.0
TH1_k127_7328304_42 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000009381 224.0
TH1_k127_7328304_43 TIGRFAM precorrin-2 C20-methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000003566 227.0
TH1_k127_7328304_44 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000001253 221.0
TH1_k127_7328304_45 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000001451 213.0
TH1_k127_7328304_46 YbbR-like protein - - - 0.00000000000000000000000000000000000000000000000000000004171 204.0
TH1_k127_7328304_47 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000006666 196.0
TH1_k127_7328304_48 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000004186 194.0
TH1_k127_7328304_49 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000006801 189.0
TH1_k127_7328304_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 528.0
TH1_k127_7328304_50 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000001716 190.0
TH1_k127_7328304_51 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000005776 189.0
TH1_k127_7328304_52 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000006874 183.0
TH1_k127_7328304_53 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000007058 182.0
TH1_k127_7328304_54 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000002632 181.0
TH1_k127_7328304_55 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000008346 178.0
TH1_k127_7328304_56 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000000000004699 164.0
TH1_k127_7328304_57 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000001375 166.0
TH1_k127_7328304_58 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000002788 169.0
TH1_k127_7328304_59 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000002898 166.0
TH1_k127_7328304_6 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 541.0
TH1_k127_7328304_60 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000118 169.0
TH1_k127_7328304_61 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000001526 163.0
TH1_k127_7328304_62 PFAM PHP domain - - - 0.00000000000000000000000000000000000006691 150.0
TH1_k127_7328304_63 Cobalamin-5-phosphate synthase K02233 - 2.7.8.26 0.000000000000000000000000000000000006306 148.0
TH1_k127_7328304_65 KR domain - - - 0.0000000000000000000000000009716 121.0
TH1_k127_7328304_66 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000005749 102.0
TH1_k127_7328304_67 Regulatory protein, FmdB family - - - 0.000000000000000000002248 94.0
TH1_k127_7328304_68 Protein of unknown function (DUF1648) - - - 0.00000000000000000001478 99.0
TH1_k127_7328304_69 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 - 0.0000000000000000000253 93.0
TH1_k127_7328304_7 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 509.0
TH1_k127_7328304_70 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000009207 104.0
TH1_k127_7328304_71 energy transducer activity K03646,K03832 - - 0.0000000000000000005292 96.0
TH1_k127_7328304_72 - - - - 0.000000000000001861 77.0
TH1_k127_7328304_74 S-layer homology domain - - - 0.00000003956 64.0
TH1_k127_7328304_75 Short C-terminal domain K08982 - - 0.0000007346 55.0
TH1_k127_7328304_77 - - - - 0.000002271 54.0
TH1_k127_7328304_78 amine dehydrogenase activity - - - 0.00001675 50.0
TH1_k127_7328304_8 PFAM Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 487.0
TH1_k127_7328304_9 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 482.0
TH1_k127_7372776_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 4.112e-209 663.0
TH1_k127_7372776_1 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000000001141 151.0
TH1_k127_7372776_2 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000009205 108.0
TH1_k127_7446631_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 2.622e-296 934.0
TH1_k127_7446631_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 7.486e-276 867.0
TH1_k127_7446631_2 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.802e-258 807.0
TH1_k127_7446631_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009068 283.0
TH1_k127_7446631_4 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001821 278.0
TH1_k127_7446631_5 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000739 241.0
TH1_k127_7446631_6 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000004519 143.0
TH1_k127_7446631_7 Transcriptional regulator, MerR family - - - 0.000000000000000000000000000001874 127.0
TH1_k127_7446631_8 - - - - 0.000000000000001269 83.0
TH1_k127_7447147_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 368.0
TH1_k127_7447147_1 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000001266 160.0
TH1_k127_7454391_0 FecR protein - - - 0.0 1039.0
TH1_k127_7454391_1 Telomere recombination K04656 - - 1.292e-257 818.0
TH1_k127_7454391_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000001899 218.0
TH1_k127_7454391_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000002627 212.0
TH1_k127_7454391_12 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000468 197.0
TH1_k127_7454391_13 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000000000000000000000000006318 188.0
TH1_k127_7454391_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000003029 183.0
TH1_k127_7454391_15 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000004491 161.0
TH1_k127_7454391_16 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000007344 156.0
TH1_k127_7454391_17 cell redox homeostasis K02199 - - 0.00000000000000000000000000000003338 134.0
TH1_k127_7454391_18 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000001204 131.0
TH1_k127_7454391_19 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000053 124.0
TH1_k127_7454391_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.786e-200 638.0
TH1_k127_7454391_20 nickel cation binding K04651,K19640 - - 0.00000000000000000000000000002003 121.0
TH1_k127_7454391_21 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000403 112.0
TH1_k127_7454391_22 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000001096 93.0
TH1_k127_7454391_24 Bacterial protein of unknown function (DUF948) - - - 0.0004867 48.0
TH1_k127_7454391_25 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0009065 44.0
TH1_k127_7454391_3 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 555.0
TH1_k127_7454391_4 Male sterility protein K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 533.0
TH1_k127_7454391_5 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 348.0
TH1_k127_7454391_6 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 316.0
TH1_k127_7454391_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 314.0
TH1_k127_7454391_8 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 295.0
TH1_k127_7454391_9 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 284.0
TH1_k127_7454764_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 383.0
TH1_k127_7454764_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 346.0
TH1_k127_7454764_2 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000002488 269.0
TH1_k127_7454764_3 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002181 257.0
TH1_k127_7454764_4 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K05587 - 1.6.5.3 0.0000000000000000000000000000001323 129.0
TH1_k127_7501055_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 4.591e-202 643.0
TH1_k127_7501055_1 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 610.0
TH1_k127_7501055_2 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 584.0
TH1_k127_7501055_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 411.0
TH1_k127_7501055_4 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 406.0
TH1_k127_7501055_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 327.0
TH1_k127_7501055_6 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000253 250.0
TH1_k127_7501055_7 PFAM Isochorismatase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000003675 221.0
TH1_k127_7501055_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000006624 194.0
TH1_k127_7501055_9 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000001014 132.0
TH1_k127_7522799_0 histidine kinase HAMP region domain protein - - - 1.807e-203 668.0
TH1_k127_7522799_1 General secretory system II, protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 526.0
TH1_k127_7522799_2 Protein of unknown function (DUF763) K09003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 465.0
TH1_k127_7522799_3 Mo-molybdopterin cofactor metabolic process K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001992 252.0
TH1_k127_7522799_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000727 200.0
TH1_k127_7522799_5 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000001209 169.0
TH1_k127_7522799_6 carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000005344 149.0
TH1_k127_754406_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 563.0
TH1_k127_754406_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 446.0
TH1_k127_754406_10 bacterial (prokaryotic) histone like domain K04764 - - 0.0000000000000000000000000007632 116.0
TH1_k127_754406_2 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 341.0
TH1_k127_754406_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003486 248.0
TH1_k127_754406_4 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000734 208.0
TH1_k127_754406_5 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000000000000006874 153.0
TH1_k127_754406_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000001253 142.0
TH1_k127_754406_7 Protein of unknown function (DUF1284) K09706 - - 0.000000000000000000000000000000005722 132.0
TH1_k127_754406_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000001177 124.0
TH1_k127_754406_9 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000001289 126.0
TH1_k127_7575034_0 Domain of unknown function DUF11 - - - 1.748e-278 889.0
TH1_k127_7575034_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.476e-228 721.0
TH1_k127_7575034_10 PFAM regulatory protein AsnC Lrp family - - - 0.000000049 59.0
TH1_k127_7575034_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 505.0
TH1_k127_7575034_3 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 426.0
TH1_k127_7575034_4 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000929 287.0
TH1_k127_7575034_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000007387 267.0
TH1_k127_7575034_6 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000008306 244.0
TH1_k127_7575034_7 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step K05985,K07476 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 0.000000000000000000000000000000000000000000005372 169.0
TH1_k127_7575034_8 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000105 109.0
TH1_k127_7575034_9 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000005409 81.0
TH1_k127_7610599_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 351.0
TH1_k127_7610599_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 334.0
TH1_k127_7610599_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004138 273.0
TH1_k127_7610599_3 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000006245 213.0
TH1_k127_7610599_4 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000001838 171.0
TH1_k127_7610599_5 - - - - 0.0000000000000000000141 94.0
TH1_k127_7633861_0 COGs COG1639 signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000000006341 234.0
TH1_k127_7633861_1 4Fe-4S binding domain - - - 0.0000000000000004296 83.0
TH1_k127_7633861_2 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000004212 68.0
TH1_k127_7674387_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 356.0
TH1_k127_7696178_0 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 581.0
TH1_k127_7696178_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 541.0
TH1_k127_7696178_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 308.0
TH1_k127_7696178_3 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005983 267.0
TH1_k127_7696178_4 EamA-like transporter family - - - 0.00000000000000000000000009467 117.0
TH1_k127_7696178_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000006655 110.0
TH1_k127_7696178_6 PFAM GCN5-related N-acetyltransferase - - - 0.00000005622 55.0
TH1_k127_7748241_0 40-residue yvtn family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 296.0
TH1_k127_7748241_1 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001611 243.0
TH1_k127_7748241_2 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000001725 128.0
TH1_k127_7748241_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000001242 113.0
TH1_k127_7756713_0 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 477.0
TH1_k127_7756713_1 DoxX K15977 - - 0.000000000000000000000000000000000000000000001733 169.0
TH1_k127_7756713_2 Tim44 - - - 0.0000000000000000000000000000000000000000002362 162.0
TH1_k127_7765378_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 368.0
TH1_k127_7765378_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 330.0
TH1_k127_7765378_2 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000005355 109.0
TH1_k127_7808157_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 511.0
TH1_k127_7808157_1 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 396.0
TH1_k127_7808157_10 - - - - 0.00002025 51.0
TH1_k127_7808157_2 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 342.0
TH1_k127_7808157_3 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000001341 228.0
TH1_k127_7808157_4 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001263 223.0
TH1_k127_7808157_5 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000002307 205.0
TH1_k127_7808157_6 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000001714 191.0
TH1_k127_7808157_7 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000011 144.0
TH1_k127_7808157_9 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000001083 106.0
TH1_k127_7863561_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 467.0
TH1_k127_7863561_1 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 460.0
TH1_k127_7863561_2 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 436.0
TH1_k127_7863561_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 404.0
TH1_k127_7863561_4 response regulator receiver K02481,K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 375.0
TH1_k127_7863561_5 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 364.0
TH1_k127_7863561_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001075 271.0
TH1_k127_7863561_7 HDOD domain - - - 0.000000000000000000000000000000000000000000000000001927 192.0
TH1_k127_7863561_8 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000001638 95.0
TH1_k127_7870263_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.024e-222 694.0
TH1_k127_7870263_1 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000001111 180.0
TH1_k127_7870263_2 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000002034 169.0
TH1_k127_7870263_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000216 151.0
TH1_k127_7870263_4 histidine kinase A domain protein - - - 0.0000000000000001149 87.0
TH1_k127_7872355_0 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 4.844e-221 689.0
TH1_k127_7872355_1 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000000000000000000000000000000000000000000003303 238.0
TH1_k127_7872355_2 Type VI secretion system effector, Hcp K11903 - - 0.0000001996 56.0
TH1_k127_7883151_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 541.0
TH1_k127_7883151_1 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000009711 172.0
TH1_k127_7883151_2 Protein of unknown function (DUF2868) - - - 0.000000000000000001737 100.0
TH1_k127_7939855_0 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 323.0
TH1_k127_7939855_1 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000000000000000008324 169.0
TH1_k127_7939855_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000001554 143.0
TH1_k127_7950103_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 7.271e-315 975.0
TH1_k127_7950103_1 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 509.0
TH1_k127_7950103_2 Sensory domain found in PocR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 329.0
TH1_k127_7950103_3 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002415 278.0
TH1_k127_7950103_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000001607 129.0
TH1_k127_7990004_0 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 485.0
TH1_k127_7990004_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000263 202.0
TH1_k127_8037932_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 557.0
TH1_k127_8037932_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 557.0
TH1_k127_8037932_2 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005185 287.0
TH1_k127_8037932_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000001813 218.0
TH1_k127_8037932_4 - - - - 0.00000000001629 70.0
TH1_k127_813165_0 Domain of unknown function (DUF3413) K07014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 394.0
TH1_k127_813165_1 PFAM glycosyl transferase, family 9 K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 326.0
TH1_k127_813165_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000004292 241.0
TH1_k127_813165_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000001415 207.0
TH1_k127_813165_4 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.0000000000000000000000000000000000005981 153.0
TH1_k127_813165_5 Glycosyltransferase Family 4 - - - 0.000000000000000000177 96.0
TH1_k127_8163319_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1699.0
TH1_k127_8163319_1 Glycosyl transferase family 21 - - - 4.102e-202 640.0
TH1_k127_8163319_10 nucleotide metabolic process - - - 0.000000000000000000000000000000000004054 145.0
TH1_k127_8163319_11 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000002857 124.0
TH1_k127_8163319_12 ER membrane protein complex subunit - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006457,GO:0008150,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0032991,GO:0034975,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0072546,GO:0098796,GO:0098827 - 0.00006303 55.0
TH1_k127_8163319_2 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 2.24e-200 646.0
TH1_k127_8163319_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 575.0
TH1_k127_8163319_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 374.0
TH1_k127_8163319_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001568 262.0
TH1_k127_8163319_6 serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000002548 273.0
TH1_k127_8163319_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000007934 246.0
TH1_k127_8163319_9 - - - - 0.00000000000000000000000000000000000000000000000000000000007777 207.0
TH1_k127_8171105_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 296.0
TH1_k127_8171105_1 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000003355 187.0
TH1_k127_8171105_2 metal cluster binding K06940 - - 0.00000000000000000000000000000000000000000000000001774 188.0
TH1_k127_8171105_3 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000006766 191.0
TH1_k127_8171105_4 Diadenylate cyclase - - - 0.0000000000000000000000000000000000000000001295 170.0
TH1_k127_8171105_5 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.000000000005006 76.0
TH1_k127_8185333_0 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 396.0
TH1_k127_8185333_1 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 383.0
TH1_k127_8195662_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000000000002975 112.0
TH1_k127_8195662_1 PFAM GCN5-related N-acetyltransferase - - - 0.0001961 51.0
TH1_k127_8212718_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 385.0
TH1_k127_8212718_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 305.0
TH1_k127_8212718_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001293 237.0
TH1_k127_8212718_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006057 237.0
TH1_k127_8212718_4 CHASE2 - - - 0.0000000000000000000000000000000000000000000000000000000000001339 223.0
TH1_k127_8212718_5 YtkA-like - - - 0.00000000000000000000000005883 116.0
TH1_k127_8212718_6 PFAM response regulator receiver K07657 - - 0.000000000000000000002927 101.0
TH1_k127_8217789_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1268.0
TH1_k127_8217789_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 316.0
TH1_k127_8217789_2 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.00000000000000000000000000000000000000000000001399 175.0
TH1_k127_8217789_3 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000001848 139.0
TH1_k127_8217789_4 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.000000000000000000001855 95.0
TH1_k127_8384708_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 9.342e-202 646.0
TH1_k127_8483998_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1213.0
TH1_k127_8483998_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 485.0
TH1_k127_8483998_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 377.0
TH1_k127_8483998_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000319 220.0
TH1_k127_8483998_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000004677 87.0
TH1_k127_8483998_5 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000396 81.0
TH1_k127_849582_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1058.0
TH1_k127_849582_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.736e-246 767.0
TH1_k127_849582_10 Bacterial regulatory protein, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 417.0
TH1_k127_849582_11 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 406.0
TH1_k127_849582_12 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 407.0
TH1_k127_849582_13 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004457 253.0
TH1_k127_849582_14 phosphorelay sensor kinase activity K07709,K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000006678 252.0
TH1_k127_849582_15 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000002969 242.0
TH1_k127_849582_16 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000003894 224.0
TH1_k127_849582_17 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000007606 218.0
TH1_k127_849582_18 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000007962 226.0
TH1_k127_849582_19 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000007826 213.0
TH1_k127_849582_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 581.0
TH1_k127_849582_20 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000001134 191.0
TH1_k127_849582_21 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000009159 191.0
TH1_k127_849582_22 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000002077 198.0
TH1_k127_849582_23 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000002502 169.0
TH1_k127_849582_24 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000001014 169.0
TH1_k127_849582_25 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000006407 156.0
TH1_k127_849582_26 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.00000000000000000000000000000000000004395 148.0
TH1_k127_849582_27 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000003083 139.0
TH1_k127_849582_28 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000000008053 122.0
TH1_k127_849582_3 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 562.0
TH1_k127_849582_30 PFAM HNH endonuclease K07451 - - 0.00000000000000000000000000001618 124.0
TH1_k127_849582_31 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000001282 110.0
TH1_k127_849582_32 Cytochrome P460 - - - 0.0000000000000000000000000265 116.0
TH1_k127_849582_33 Protein of unknown function (DUF507) - - - 0.00000000000000000000000002844 110.0
TH1_k127_849582_34 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 0.0000000000000000000000000356 110.0
TH1_k127_849582_35 electron transfer activity K05337,K17247 - - 0.0000000000000000000000003058 106.0
TH1_k127_849582_37 - - - - 0.0000000000000000003118 89.0
TH1_k127_849582_4 GHKL domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 563.0
TH1_k127_849582_5 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 544.0
TH1_k127_849582_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 490.0
TH1_k127_849582_7 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 447.0
TH1_k127_849582_8 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 442.0
TH1_k127_849582_9 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 426.0
TH1_k127_8551966_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.433e-293 908.0
TH1_k127_8551966_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 3.841e-209 661.0
TH1_k127_8551966_10 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000002291 139.0
TH1_k127_8551966_12 - - - - 0.000000000000000008327 85.0
TH1_k127_8551966_13 cell wall hydrolase K01448 - 3.5.1.28 0.0000000000002419 83.0
TH1_k127_8551966_14 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000002314 57.0
TH1_k127_8551966_15 HAMP domain - - - 0.0005313 51.0
TH1_k127_8551966_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 614.0
TH1_k127_8551966_3 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 426.0
TH1_k127_8551966_4 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 383.0
TH1_k127_8551966_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 347.0
TH1_k127_8551966_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 346.0
TH1_k127_8551966_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 321.0
TH1_k127_8551966_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001181 278.0
TH1_k127_8551966_9 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000008364 150.0
TH1_k127_8557053_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 361.0
TH1_k127_8557053_1 proteolysis K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000006817 240.0
TH1_k127_8557053_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000775 166.0
TH1_k127_8557053_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000009694 143.0
TH1_k127_8557053_4 Stringent starvation protein B K09985 - - 0.000000000000000000000000006861 120.0
TH1_k127_8562605_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 522.0
TH1_k127_8562605_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000003968 208.0
TH1_k127_8562605_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000001531 180.0
TH1_k127_8603632_0 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 605.0
TH1_k127_8603632_1 Hsp20/alpha crystallin family K13993 - - 0.0000001658 55.0
TH1_k127_8612257_0 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 529.0
TH1_k127_8612257_1 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 304.0
TH1_k127_8612257_2 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002766 244.0
TH1_k127_8612257_3 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000001776 215.0
TH1_k127_8612257_4 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.00000000000000000000000000000000000000000000000000000000002264 217.0
TH1_k127_8612257_5 Cytochrome c - - - 0.0000000000000000000000000000003266 128.0
TH1_k127_8647704_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 567.0
TH1_k127_8647704_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 470.0
TH1_k127_8647704_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 360.0
TH1_k127_8647704_3 Aconitase C-terminal domain K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000142 184.0
TH1_k127_8647704_4 Thioredoxin-like - - - 0.000000000000000000000000000000000003416 144.0
TH1_k127_8671100_0 protein secretion K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 575.0
TH1_k127_8671100_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 349.0
TH1_k127_8671100_2 Surface antigen K07277 - - 0.00000000328 64.0
TH1_k127_8678136_0 - K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 441.0
TH1_k127_8678136_1 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 422.0
TH1_k127_8678136_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 399.0
TH1_k127_8678136_3 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 395.0
TH1_k127_8678136_4 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000001959 196.0
TH1_k127_8678136_5 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000000218 194.0
TH1_k127_8678136_6 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000024 182.0
TH1_k127_8678136_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000002038 127.0
TH1_k127_8678136_8 - - - - 0.00005827 55.0
TH1_k127_8681470_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 458.0
TH1_k127_8681470_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 346.0
TH1_k127_8681470_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 335.0
TH1_k127_8681470_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172,K18357 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000001075 220.0
TH1_k127_8681470_4 Belongs to the peptidase S8 family - - - 0.00000000000000000000003621 103.0
TH1_k127_8686931_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 502.0
TH1_k127_8686931_1 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 437.0
TH1_k127_8686931_10 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000006192 196.0
TH1_k127_8686931_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000007973 192.0
TH1_k127_8686931_12 OstA-like protein K09774 - - 0.000000000000000000000000000000000000000000001528 170.0
TH1_k127_8686931_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000004752 124.0
TH1_k127_8686931_14 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000006389 70.0
TH1_k127_8686931_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 355.0
TH1_k127_8686931_3 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 317.0
TH1_k127_8686931_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 303.0
TH1_k127_8686931_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 290.0
TH1_k127_8686931_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 289.0
TH1_k127_8686931_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001405 244.0
TH1_k127_8686931_8 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000001039 213.0
TH1_k127_8686931_9 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000002672 196.0
TH1_k127_8690999_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.868e-318 1002.0
TH1_k127_8690999_1 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 410.0
TH1_k127_8690999_2 Restriction endonuclease XhoI - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 299.0
TH1_k127_8690999_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588,K01945 - 5.4.99.18,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000002333 244.0
TH1_k127_8690999_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000005803 242.0
TH1_k127_8690999_5 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000000000001316 163.0
TH1_k127_8690999_6 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000008595 152.0
TH1_k127_8690999_7 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000468 64.0
TH1_k127_8712702_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000053 223.0
TH1_k127_8712702_1 Protein of unknown function, DUF480 K09915 - - 0.000000000000000000000000000000000000000000000000000000000000007795 222.0
TH1_k127_8712702_2 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000001293 216.0
TH1_k127_8712702_3 COGs COG4446 conserved - - - 0.0000000000000000000000000002157 119.0
TH1_k127_8726196_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 7.305e-203 649.0
TH1_k127_8726196_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 552.0
TH1_k127_8726196_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 348.0
TH1_k127_8726196_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 314.0
TH1_k127_8726196_12 PFAM Aminotransferase class I and II K00639,K00652,K01906 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47,6.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006123 286.0
TH1_k127_8726196_13 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001316 273.0
TH1_k127_8726196_14 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000706 253.0
TH1_k127_8726196_15 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000000000000111 204.0
TH1_k127_8726196_16 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000007526 208.0
TH1_k127_8726196_17 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000007172 112.0
TH1_k127_8726196_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 519.0
TH1_k127_8726196_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 465.0
TH1_k127_8726196_4 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 432.0
TH1_k127_8726196_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 398.0
TH1_k127_8726196_6 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 372.0
TH1_k127_8726196_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 377.0
TH1_k127_8726196_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 358.0
TH1_k127_8726196_9 LysM domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 340.0
TH1_k127_8732224_0 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 332.0
TH1_k127_8732224_1 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 299.0
TH1_k127_8732224_2 Belongs to the Fur family K02076,K03711 GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000009806 185.0
TH1_k127_8732224_3 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000002243 140.0
TH1_k127_8739691_0 FtsX-like permease family K02004 - - 4.087e-298 933.0
TH1_k127_8739691_1 hexose biosynthetic process K01810 - 5.3.1.9 1.34e-287 891.0
TH1_k127_8739691_10 Ferritin Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 293.0
TH1_k127_8739691_11 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005545 250.0
TH1_k127_8739691_12 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000005185 222.0
TH1_k127_8739691_13 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000001035 203.0
TH1_k127_8739691_14 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000002106 196.0
TH1_k127_8739691_15 HDOD domain - - - 0.000000000000000000000000000000000000000000001104 176.0
TH1_k127_8739691_16 - - - - 0.0000000000000000000000722 106.0
TH1_k127_8739691_17 Protein of unknown function (DUF3187) - - - 0.0000000000000000000002741 109.0
TH1_k127_8739691_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 3.555e-235 743.0
TH1_k127_8739691_3 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 539.0
TH1_k127_8739691_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 388.0
TH1_k127_8739691_5 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 380.0
TH1_k127_8739691_6 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 354.0
TH1_k127_8739691_7 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 358.0
TH1_k127_8739691_8 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 355.0
TH1_k127_8739691_9 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 347.0
TH1_k127_8740488_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.287e-293 917.0
TH1_k127_8740488_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.424e-293 909.0
TH1_k127_8740488_10 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000116 134.0
TH1_k127_8740488_11 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000001246 132.0
TH1_k127_8740488_12 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000006304 89.0
TH1_k127_8740488_13 Belongs to the UPF0434 family K09791 - - 0.000000000000000004149 85.0
TH1_k127_8740488_14 Cupin 2, conserved barrel domain protein - - - 0.000000000006167 70.0
TH1_k127_8740488_15 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000001119 62.0
TH1_k127_8740488_16 HicA toxin of bacterial toxin-antitoxin, K07339 - - 0.0000003975 53.0
TH1_k127_8740488_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.738e-201 636.0
TH1_k127_8740488_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 6.3e-198 626.0
TH1_k127_8740488_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 417.0
TH1_k127_8740488_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 402.0
TH1_k127_8740488_6 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 368.0
TH1_k127_8740488_7 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 364.0
TH1_k127_8740488_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000007602 209.0
TH1_k127_8740488_9 - - - - 0.000000000000000000000000000000000000000000000000009342 184.0
TH1_k127_8762198_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.34e-221 693.0
TH1_k127_8762198_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 408.0
TH1_k127_8762198_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000034 226.0
TH1_k127_8762198_3 CTP:tRNA cytidylyltransferase activity K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000003795 207.0
TH1_k127_8762198_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000005384 206.0
TH1_k127_8762198_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000004353 179.0
TH1_k127_8762198_6 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000002714 107.0
TH1_k127_8768692_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1007.0
TH1_k127_8768692_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 536.0
TH1_k127_8768692_2 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 461.0
TH1_k127_8768692_3 metal-dependent enzyme K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
TH1_k127_8768692_4 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000003317 114.0
TH1_k127_880439_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 520.0
TH1_k127_880439_1 cysteine-tRNA ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 447.0
TH1_k127_880439_11 deoxyhypusine monooxygenase activity K05386 - - 0.00000000000000001452 90.0
TH1_k127_880439_2 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 435.0
TH1_k127_880439_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 377.0
TH1_k127_880439_4 Glycosyl transferase group 1 K00696,K13058 GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,2.4.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000002982 279.0
TH1_k127_880439_5 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000002773 235.0
TH1_k127_880439_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000002093 218.0
TH1_k127_880439_7 Transcriptional - - - 0.0000000000000000000000000000000005277 134.0
TH1_k127_880439_8 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000002981 132.0
TH1_k127_880439_9 protein domain associated with - - - 0.00000000000000000000000000001661 123.0
TH1_k127_8837945_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 390.0
TH1_k127_8837945_1 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 395.0
TH1_k127_8837945_2 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009353 251.0
TH1_k127_8837945_3 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000000000000000008192 141.0
TH1_k127_8837945_4 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000003844 129.0
TH1_k127_8837945_6 - - - - 0.0009593 44.0
TH1_k127_8839239_0 Endoribonuclease that initiates mRNA decay K18682 - - 7.74e-215 678.0
TH1_k127_8839239_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 444.0
TH1_k127_8839239_10 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000005016 186.0
TH1_k127_8839239_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000006059 180.0
TH1_k127_8839239_12 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000001326 168.0
TH1_k127_8839239_13 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000002153 119.0
TH1_k127_8839239_2 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 358.0
TH1_k127_8839239_3 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 359.0
TH1_k127_8839239_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 323.0
TH1_k127_8839239_5 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 321.0
TH1_k127_8839239_6 pfam abc K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007452 282.0
TH1_k127_8839239_7 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001356 280.0
TH1_k127_8839239_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000031 291.0
TH1_k127_8839239_9 phosphinothricin N-acetyltransferase activity K03823 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000000002992 222.0
TH1_k127_8972401_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.057e-243 763.0
TH1_k127_8972401_1 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 3.202e-238 744.0
TH1_k127_8972401_10 PFAM Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 321.0
TH1_k127_8972401_11 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001174 239.0
TH1_k127_8972401_12 PIN domain - - - 0.000000000000000000000000000000000000000000000000000000000002642 211.0
TH1_k127_8972401_13 nitric oxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000003559 203.0
TH1_k127_8972401_14 Uncharacterized ACR, COG1678 - - - 0.000000000000000000000000000000000000562 150.0
TH1_k127_8972401_15 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000000000000003317 126.0
TH1_k127_8972401_16 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000001742 139.0
TH1_k127_8972401_17 protein conserved in bacteria - - - 0.0000000000000000000001925 106.0
TH1_k127_8972401_18 - - - - 0.00000000000000005839 87.0
TH1_k127_8972401_19 - - - - 0.000000000000156 75.0
TH1_k127_8972401_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.675e-197 625.0
TH1_k127_8972401_20 electron transfer activity K05337,K17247 - - 0.000000001106 61.0
TH1_k127_8972401_21 - - - - 0.000000001611 61.0
TH1_k127_8972401_22 Domain of unknown function (DUF4912) K09942 - - 0.0000002613 62.0
TH1_k127_8972401_3 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 599.0
TH1_k127_8972401_4 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 562.0
TH1_k127_8972401_5 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 551.0
TH1_k127_8972401_6 TOBE domain K02019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 410.0
TH1_k127_8972401_7 Cys Met metabolism K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 391.0
TH1_k127_8972401_8 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 335.0
TH1_k127_8972401_9 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 323.0
TH1_k127_9005079_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 377.0
TH1_k127_9005079_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000007283 233.0
TH1_k127_9005079_3 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000002242 131.0
TH1_k127_9020731_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1620.0
TH1_k127_9020731_1 Belongs to the heat shock protein 70 family - - - 8.236e-245 787.0
TH1_k127_9020731_2 Heat shock protein 70 family - - - 1.229e-202 647.0
TH1_k127_9020731_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 403.0
TH1_k127_9020731_4 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003787 262.0
TH1_k127_9020731_5 Domain of unknown function (DUF2760) - - - 0.000000000000000000000000000000000000001089 156.0
TH1_k127_9020731_6 - - - - 0.000000000000000000009735 98.0
TH1_k127_9021563_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 428.0
TH1_k127_9021563_1 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 388.0
TH1_k127_9021563_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000004741 174.0
TH1_k127_9021563_3 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.000000000000004717 78.0
TH1_k127_9113942_0 Psort location CytoplasmicMembrane, score K01990,K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000001241 252.0
TH1_k127_9113942_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000009748 226.0
TH1_k127_9113942_2 Transport permease protein K01992,K09690 - - 0.000000000000000000000000000000000000000000000000002446 192.0
TH1_k127_9113942_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000001536 170.0
TH1_k127_9113942_4 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.00000000000000000000000000000000000002727 160.0
TH1_k127_9113942_5 arylsulfatase activity - - - 0.00000000000000003163 96.0
TH1_k127_9113942_6 S-layer homology domain - - - 0.000426 53.0
TH1_k127_9166852_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 454.0
TH1_k127_9166852_1 Bacterial type II and III secretion system protein K02453,K03219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 312.0
TH1_k127_9166852_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000001722 212.0
TH1_k127_9166852_3 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000002511 210.0
TH1_k127_9166852_4 beta-fructofuranosidase activity - - - 0.0000001353 59.0
TH1_k127_9227856_0 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 507.0
TH1_k127_9227856_1 PFAM Transketolase central region K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 456.0
TH1_k127_9227856_2 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 396.0
TH1_k127_9227856_3 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 369.0
TH1_k127_9227856_4 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000003056 205.0
TH1_k127_9227856_5 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000004562 161.0
TH1_k127_9227856_6 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000115 60.0
TH1_k127_9283013_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1327.0
TH1_k127_9283013_1 Transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 335.0
TH1_k127_9283013_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000003791 179.0
TH1_k127_9283013_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000003314 126.0
TH1_k127_930843_0 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 591.0
TH1_k127_930843_1 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 536.0
TH1_k127_930843_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 441.0
TH1_k127_930843_3 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 346.0
TH1_k127_930843_4 Response regulator receiver domain - - - 0.00000000000000000000000000007115 117.0
TH1_k127_9363139_0 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007328 263.0
TH1_k127_9363139_1 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000003987 231.0
TH1_k127_9363139_2 Protein of unknown function (DUF1318) - - - 0.00000000000000000000000000000000000000000006447 169.0
TH1_k127_9363139_3 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000000000002675 145.0
TH1_k127_9363139_4 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000034 115.0
TH1_k127_9363139_5 - - - - 0.00000000000000000000006852 113.0
TH1_k127_9363139_6 - - - - 0.0000000000002157 74.0
TH1_k127_9405354_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 395.0
TH1_k127_9405354_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 293.0
TH1_k127_9405354_2 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001187 277.0
TH1_k127_9405354_3 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002119 265.0
TH1_k127_9405354_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000001802 199.0
TH1_k127_9545436_0 PFAM NHL repeat containing protein - - - 0.0 1588.0
TH1_k127_9545436_1 PD-(D/E)XK nuclease superfamily - - - 9.51e-220 717.0
TH1_k127_9545436_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002869 258.0
TH1_k127_9545436_11 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000002548 218.0
TH1_k127_9545436_12 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000000004834 177.0
TH1_k127_9545436_13 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000005365 168.0
TH1_k127_9545436_14 Belongs to the peptidase S8 family - - - 0.000000000000000000000000001374 133.0
TH1_k127_9545436_15 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000271 91.0
TH1_k127_9545436_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.695e-201 631.0
TH1_k127_9545436_3 Belongs to the helicase family. UvrD subfamily - - - 8.523e-201 659.0
TH1_k127_9545436_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 428.0
TH1_k127_9545436_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 420.0
TH1_k127_9545436_6 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 397.0
TH1_k127_9545436_7 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 343.0
TH1_k127_9545436_8 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 294.0
TH1_k127_9545436_9 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003334 271.0
TH1_k127_976493_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 359.0
TH1_k127_976493_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 343.0
TH1_k127_976493_2 biosynthesis glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001738 241.0
TH1_k127_976493_3 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000004326 231.0
TH1_k127_976493_4 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000613 209.0
TH1_k127_976493_5 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000007132 164.0