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Overview

ID MAG03848
Name TH1_bin.16
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Desulfobaccia
Order Desulfobaccales
Family 0-14-0-80-60-11
Genus JAILZL01
Species
Assembly information
Completeness (%) 72.11
Contamination (%) 2.78
GC content (%) 63.0
N50 (bp) 3,421
Genome size (bp) 1,927,004

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1943

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_1037656_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 505.0
TH1_k127_1037656_1 GNAT family acetyltransferase - - - 0.000003657 55.0
TH1_k127_1060497_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.805e-279 888.0
TH1_k127_1060497_1 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000005455 184.0
TH1_k127_1068901_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.229e-198 626.0
TH1_k127_1068901_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000005201 95.0
TH1_k127_1085025_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 325.0
TH1_k127_1085025_1 domain protein - - - 0.00000000000000000000000000000000000002109 156.0
TH1_k127_1087679_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.088e-235 741.0
TH1_k127_1091817_0 PFAM Type II secretion system protein E K02283,K03609 - - 8.715e-215 674.0
TH1_k127_1091817_1 AAA domain K02282 - - 0.000000000000000000000000000000000000005586 154.0
TH1_k127_1091817_2 PFAM Type II secretion system protein E K02283,K03609 - - 0.0000000000000000258 84.0
TH1_k127_1107262_0 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 413.0
TH1_k127_1107262_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000005761 162.0
TH1_k127_1107262_2 TIGRFAM thiazole biosynthesis protein ThiH K03150 - 4.1.99.19 0.0006373 44.0
TH1_k127_1115113_0 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004972 272.0
TH1_k127_1115113_1 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000009781 243.0
TH1_k127_1115113_2 NUDIX domain - - - 0.000000000000000000000000000000000000000000002327 171.0
TH1_k127_1115113_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000004961 87.0
TH1_k127_1127807_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000001871 185.0
TH1_k127_1127807_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000003227 178.0
TH1_k127_1127807_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis - - - 0.000000000000000000000000000000002571 138.0
TH1_k127_1143587_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 456.0
TH1_k127_1143587_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 409.0
TH1_k127_1143587_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 332.0
TH1_k127_1143587_3 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 319.0
TH1_k127_1143587_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 264.0
TH1_k127_1143587_5 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000000000000000000000000000007669 231.0
TH1_k127_1143587_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000003263 162.0
TH1_k127_1143587_7 Mo-molybdopterin cofactor metabolic process K02379,K03750,K03752,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.000000000000000000000004461 109.0
TH1_k127_1143587_8 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.0000000000000006063 81.0
TH1_k127_1154360_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 607.0
TH1_k127_1154360_1 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001985 154.0
TH1_k127_1154360_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000001088 72.0
TH1_k127_1167149_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001267 273.0
TH1_k127_1167149_1 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000001354 191.0
TH1_k127_1167149_2 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000003918 157.0
TH1_k127_1167149_3 Histidine kinase - - - 0.0000000000000000000000000000000001779 142.0
TH1_k127_1177852_0 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 285.0
TH1_k127_1177852_1 PFAM CBS domain K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007879 271.0
TH1_k127_1177852_2 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000006834 248.0
TH1_k127_1177852_3 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000001488 221.0
TH1_k127_1212851_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.943e-208 655.0
TH1_k127_1212851_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 526.0
TH1_k127_1212851_2 ACT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009108 244.0
TH1_k127_122299_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 520.0
TH1_k127_122299_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000001532 119.0
TH1_k127_122299_2 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000517 64.0
TH1_k127_1263245_0 SMART Elongator protein 3 MiaB NifB - - - 7.246e-209 655.0
TH1_k127_1263245_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 316.0
TH1_k127_1263245_2 - - - - 0.000000000000000000000000000001135 122.0
TH1_k127_1296314_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.248e-215 678.0
TH1_k127_1299253_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000001858 201.0
TH1_k127_1299253_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins - - - 0.00000000000000000000000000000000000000000000002451 178.0
TH1_k127_1299253_3 Protein of unknown function (DUF3426) - - - 0.000000000000000002954 95.0
TH1_k127_1299253_4 Transposase DDE domain K07481 - - 0.0000000000000001126 83.0
TH1_k127_13215_0 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 2.315e-283 877.0
TH1_k127_13215_1 Thioesterase K01075,K07107 - 3.1.2.23 0.00000000000000000000000000000000000000000000000002318 183.0
TH1_k127_13215_2 carboxylase K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000003784 90.0
TH1_k127_137812_0 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000001156 198.0
TH1_k127_137812_1 Aldehyde dehydrogenase family K10217 - 1.2.1.32,1.2.1.85 0.00000000000000000000000004585 122.0
TH1_k127_137812_2 tRNA (guanine-N7-)-methyltransferase activity - - - 0.00000000001485 65.0
TH1_k127_1403413_0 Formylmethanofuran dehydrogenase, subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 439.0
TH1_k127_1403413_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 339.0
TH1_k127_1403413_2 acetyl-CoA catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000004145 219.0
TH1_k127_1403413_3 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000003143 205.0
TH1_k127_1403413_4 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000218 182.0
TH1_k127_1423719_0 Outer membrane cobalamin receptor protein K02014,K16092 - - 2.703e-211 676.0
TH1_k127_1423719_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000001963 201.0
TH1_k127_1424439_0 Major Facilitator Superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 409.0
TH1_k127_1424439_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000007569 123.0
TH1_k127_1424439_2 AntiSigma factor - - - 0.00007714 53.0
TH1_k127_1430611_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 386.0
TH1_k127_1430611_1 nuclease activity - - - 0.0000000000000000000000000000000000000000467 154.0
TH1_k127_1460866_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 464.0
TH1_k127_1460866_1 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 312.0
TH1_k127_1460866_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003043 246.0
TH1_k127_1460866_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000004638 131.0
TH1_k127_1479029_0 aminotransferase, class I and II K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 535.0
TH1_k127_1479029_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 447.0
TH1_k127_1479029_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001118 263.0
TH1_k127_1479029_3 - - - - 0.00000000000000000000000000000000000000000000007397 173.0
TH1_k127_1527022_0 ATPase domain of DNA mismatch repair MUTS family K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 306.0
TH1_k127_1527022_1 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000003525 153.0
TH1_k127_1527022_2 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000001243 109.0
TH1_k127_1553956_0 PFAM Glycosyl transferase, group 1 K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 370.0
TH1_k127_1553956_1 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000004338 173.0
TH1_k127_1557417_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 333.0
TH1_k127_1557417_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001258 275.0
TH1_k127_1557417_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0009726 42.0
TH1_k127_1561289_0 Type II and III secretion system protein K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 552.0
TH1_k127_1561289_1 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 243.0
TH1_k127_1561289_2 helix_turn_helix, Lux Regulon K07693 - - 0.000001109 56.0
TH1_k127_158750_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000393 235.0
TH1_k127_158750_1 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000002312 125.0
TH1_k127_1621_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 1.246e-281 877.0
TH1_k127_1621_1 COG1230 Co Zn Cd efflux system component K16264 - - 0.00000000000000000000000000000000000000000000005791 176.0
TH1_k127_1624609_0 Integral membrane sensor signal transduction histidine kinase K02482 - 2.7.13.3 2.035e-207 660.0
TH1_k127_1624609_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000004518 169.0
TH1_k127_1624609_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000006171 87.0
TH1_k127_1632156_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 542.0
TH1_k127_1632156_1 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 348.0
TH1_k127_1632156_2 OstA-like protein K09774 - - 0.000000000000000000000000000000000000000005144 163.0
TH1_k127_1632156_3 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000006063 127.0
TH1_k127_1632156_4 Lipopolysaccharide-assembly, LptC-related - - - 0.0000000000000000000005106 104.0
TH1_k127_1632156_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000002988 95.0
TH1_k127_1642217_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 410.0
TH1_k127_1642217_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 378.0
TH1_k127_1642217_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000323 198.0
TH1_k127_1642217_3 protein conserved in bacteria K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000002223 133.0
TH1_k127_1642217_4 unfolded protein binding K06142 - - 0.0006972 44.0
TH1_k127_1651648_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1844.0
TH1_k127_1651648_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 379.0
TH1_k127_1651648_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000006193 242.0
TH1_k127_1651648_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000004103 235.0
TH1_k127_1651752_0 TIGRFAM Formate dehydrogenase, gamma subunit K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 377.0
TH1_k127_1651752_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 303.0
TH1_k127_1651752_2 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000000000000000000158 187.0
TH1_k127_1651752_3 Spore maturation protein cgeB K06320 - - 0.000000000000000000000000000000000007003 151.0
TH1_k127_1651752_4 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000000000000000000000000004057 130.0
TH1_k127_165676_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000009331 270.0
TH1_k127_165676_1 Tyrosine recombinase XerD K03733,K04763 - - 0.00000000000000000000000000000000000003859 153.0
TH1_k127_165676_2 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02849 - - 0.0000000000000005767 78.0
TH1_k127_168723_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 4.039e-246 778.0
TH1_k127_168723_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K13820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009653 287.0
TH1_k127_168723_2 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002513 243.0
TH1_k127_168723_3 Role in flagellar biosynthesis K02421 - - 0.000000000000000000000000000000002519 136.0
TH1_k127_1696722_0 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 443.0
TH1_k127_1696722_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000002599 152.0
TH1_k127_170186_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1015.0
TH1_k127_171814_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000004193 213.0
TH1_k127_171814_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000624 92.0
TH1_k127_171814_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000002775 76.0
TH1_k127_171814_3 -O-antigen K02847 - - 0.00002112 57.0
TH1_k127_1729128_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 454.0
TH1_k127_1729128_1 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 340.0
TH1_k127_1729128_2 protein conserved in bacteria K09966 - - 0.00000000000000000000000000000000000000000000000000000001879 201.0
TH1_k127_1729128_3 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000000000000000002814 196.0
TH1_k127_1729128_4 COG1403 Restriction endonuclease - - - 0.000000000000000000000000001442 114.0
TH1_k127_1729128_5 Domain of unknown function (DUF4174) - - - 0.000000000000000000009884 100.0
TH1_k127_1732070_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 513.0
TH1_k127_1732070_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 353.0
TH1_k127_1732070_2 - - - - 0.000000000000000000003568 98.0
TH1_k127_1732070_3 Universal stress protein family K07090 - - 0.0000002713 57.0
TH1_k127_1732070_4 - - - - 0.0006324 48.0
TH1_k127_1755907_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 522.0
TH1_k127_1755907_1 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 443.0
TH1_k127_1755907_2 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 379.0
TH1_k127_1755907_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000006977 233.0
TH1_k127_1755907_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000003322 205.0
TH1_k127_1755907_5 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000003142 207.0
TH1_k127_1755907_6 4Fe-4S binding domain - - - 0.0000000000000000000000000000001797 126.0
TH1_k127_1756282_0 Lytic transglycosylase catalytic K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 304.0
TH1_k127_1756282_1 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001721 238.0
TH1_k127_1761677_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.22e-235 735.0
TH1_k127_1761677_1 NUDIX domain - - - 0.00000000000000000000000000000006337 128.0
TH1_k127_1772887_0 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 329.0
TH1_k127_1772887_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 315.0
TH1_k127_1772887_2 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000006336 194.0
TH1_k127_1832785_0 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K04488,K13819 - - 0.000000000000000000000000000000000000000000000000000000002807 205.0
TH1_k127_1832785_1 Domain of unknown function (DUF4091) - - - 0.00000000000000000004518 98.0
TH1_k127_183637_0 Belongs to the helicase family. UvrD subfamily - - - 1.51e-240 773.0
TH1_k127_1864860_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 2.895e-214 674.0
TH1_k127_1864860_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 340.0
TH1_k127_1864860_2 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.0000000000000000000000000002024 116.0
TH1_k127_1894390_0 PFAM CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 463.0
TH1_k127_1894390_1 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 458.0
TH1_k127_1894390_2 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000006163 205.0
TH1_k127_1894390_3 PFAM MgtE intracellular K02383 - - 0.00000253 56.0
TH1_k127_1894390_4 - - - - 0.000172 49.0
TH1_k127_1923273_0 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 558.0
TH1_k127_1923273_1 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 300.0
TH1_k127_1923273_2 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000002676 131.0
TH1_k127_1923273_3 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.000000000000000000000000000008528 120.0
TH1_k127_1923273_4 Tetratricopeptide repeat - - - 0.000000000000000002767 93.0
TH1_k127_1956226_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 418.0
TH1_k127_1956226_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000001161 96.0
TH1_k127_1957122_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 477.0
TH1_k127_1957122_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000006331 232.0
TH1_k127_1957122_2 Essential cell division protein K03589 - - 0.00000000000003459 74.0
TH1_k127_195883_0 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 414.0
TH1_k127_195883_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000001129 221.0
TH1_k127_195883_2 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000001925 174.0
TH1_k127_195883_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000009859 135.0
TH1_k127_195883_4 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000006027 73.0
TH1_k127_195883_5 Hydantoinase/oxoprolinase N-terminal region K01469,K01473 - 3.5.2.14,3.5.2.9 0.00000002687 58.0
TH1_k127_1981970_0 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 483.0
TH1_k127_1981970_1 AAA domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 356.0
TH1_k127_1981970_2 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000002305 184.0
TH1_k127_198846_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 531.0
TH1_k127_1997858_0 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 540.0
TH1_k127_1997858_1 aminotransferase, class I and II K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 533.0
TH1_k127_1997858_2 MacB-like periplasmic core domain K02004 - - 0.00004165 46.0
TH1_k127_2006142_0 FAD dependent oxidoreductase K16885 - - 1.703e-194 614.0
TH1_k127_2006142_1 reductase alpha subunit K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000009641 225.0
TH1_k127_2009141_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 430.0
TH1_k127_2009141_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000002353 195.0
TH1_k127_2009141_2 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.000000000000000000000000000000000000000132 153.0
TH1_k127_2009141_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000004493 102.0
TH1_k127_2011173_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.196e-265 833.0
TH1_k127_2011173_1 PFAM glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 529.0
TH1_k127_2011173_2 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000001942 81.0
TH1_k127_201602_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1217.0
TH1_k127_201602_1 PFAM methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000009803 214.0
TH1_k127_201602_2 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000589 96.0
TH1_k127_2017472_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 597.0
TH1_k127_2017472_1 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 491.0
TH1_k127_2017472_2 RpiR family transcriptional regulator - - - 0.0000000000000000000000002218 110.0
TH1_k127_2036216_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1035.0
TH1_k127_2036216_1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000263 280.0
TH1_k127_2037028_0 SMART metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000001613 211.0
TH1_k127_2037028_1 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000005177 194.0
TH1_k127_2037028_2 Chemotaxis protein methyltransferase K00575 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006479,GO:0006807,GO:0006935,GO:0008022,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0008983,GO:0009605,GO:0009987,GO:0010340,GO:0016020,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0032991,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051998,GO:0071704,GO:0071944,GO:0098561,GO:0140096,GO:1901564 2.1.1.80 0.00000000000000000000000000000000000002321 148.0
TH1_k127_2037028_3 phosphorelay signal transduction system K03413,K07720 - - 0.00000000000000000000000000000000001712 140.0
TH1_k127_2083051_0 Histidine kinase - - - 1.691e-260 827.0
TH1_k127_2083051_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 335.0
TH1_k127_2083051_2 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000002069 217.0
TH1_k127_2083051_3 Belongs to the UPF0296 family K09777 - - 0.0000000000000000000000000000002309 124.0
TH1_k127_2083051_5 PFAM YicC-like family, N-terminal region - - - 0.00000000009036 62.0
TH1_k127_2156433_0 Nitrite and sulphite reductase 4Fe-4S - - - 2.547e-202 639.0
TH1_k127_2156433_1 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 326.0
TH1_k127_2156433_2 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000003106 146.0
TH1_k127_2156433_3 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000008278 48.0
TH1_k127_2159246_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 406.0
TH1_k127_2159246_1 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 319.0
TH1_k127_2168204_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 1.911e-203 641.0
TH1_k127_2168204_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 597.0
TH1_k127_2168204_2 Bacterial periplasmic substrate-binding proteins K09969 - - 0.00000000000000000000000000000000000002223 148.0
TH1_k127_2168204_3 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000004135 117.0
TH1_k127_2168204_4 UMP-CMP kinase 2, mitochondrial K13809 GO:0002237,GO:0003674,GO:0003824,GO:0004127,GO:0004550,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006165,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010033,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0032496,GO:0033862,GO:0033993,GO:0034641,GO:0034654,GO:0042221,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0055086,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071396,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1901701 2.7.4.14 0.0008381 44.0
TH1_k127_2173923_0 Amidohydrolase family K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 456.0
TH1_k127_2173923_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 435.0
TH1_k127_2173923_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 355.0
TH1_k127_2179373_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 338.0
TH1_k127_2179373_1 carbon starvation protein CstA K06200 - - 0.00000000000005288 72.0
TH1_k127_2187487_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000001968 233.0
TH1_k127_2187487_1 YacP-like NYN domain K06962 - - 0.0000000000000000000000000000000001427 138.0
TH1_k127_2187487_2 Rubrerythrin - - - 0.000000000000000002196 86.0
TH1_k127_219791_0 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 428.0
TH1_k127_219791_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 409.0
TH1_k127_219791_2 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 340.0
TH1_k127_219791_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 332.0
TH1_k127_219791_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00007828 46.0
TH1_k127_2199215_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1101.0
TH1_k127_2199215_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 287.0
TH1_k127_2199215_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000003571 201.0
TH1_k127_2199215_3 - - - - 0.000000000000000000000000000000000000000000000001449 178.0
TH1_k127_2199215_4 Transcriptional regulator - - - 0.000000000000000008985 92.0
TH1_k127_2201675_0 PFAM Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 411.0
TH1_k127_2201675_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000006829 124.0
TH1_k127_2201675_2 Domain of unknown function (DUF4114) - - - 0.00000000000000000000000006068 122.0
TH1_k127_2201675_4 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00006289 46.0
TH1_k127_2201675_5 PFAM Bacterial Ig-like domain (group 2) K20276 - - 0.0008666 51.0
TH1_k127_2206838_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 388.0
TH1_k127_2206838_1 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000006171 194.0
TH1_k127_2206838_2 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000004114 167.0
TH1_k127_2206838_3 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000000000003978 144.0
TH1_k127_2209254_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 452.0
TH1_k127_2209254_1 PTS HPr component phosphorylation site K11189 - - 0.0000000001919 64.0
TH1_k127_2224015_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.86e-254 789.0
TH1_k127_2224015_1 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 301.0
TH1_k127_2250115_0 PFAM Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 454.0
TH1_k127_2250115_1 PFAM Extracellular ligand-binding receptor K07121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 401.0
TH1_k127_2250115_2 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 348.0
TH1_k127_2250115_3 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000000001641 192.0
TH1_k127_2250115_4 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000002276 162.0
TH1_k127_226816_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 377.0
TH1_k127_226816_1 - K00201 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 293.0
TH1_k127_226816_2 Acid phosphatase homologues - - - 0.0000000000000000000000000000005052 134.0
TH1_k127_2269291_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.69e-239 759.0
TH1_k127_2269291_1 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 369.0
TH1_k127_2269291_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 351.0
TH1_k127_2269291_3 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000005775 209.0
TH1_k127_2269291_4 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000002335 186.0
TH1_k127_230352_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1204.0
TH1_k127_230352_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 336.0
TH1_k127_230352_2 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006849 290.0
TH1_k127_230352_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002214 252.0
TH1_k127_230893_0 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 390.0
TH1_k127_230893_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 378.0
TH1_k127_23137_0 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 396.0
TH1_k127_23137_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 321.0
TH1_k127_23137_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000004277 57.0
TH1_k127_2317398_0 Cobalt transport protein K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000000004986 170.0
TH1_k127_2317398_1 membrane K08978,K12962 - - 0.0000000000000000000000000000000000000008034 151.0
TH1_k127_2317398_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000004622 109.0
TH1_k127_2317398_3 Protein of unknown function (DUF459) - - - 0.000004674 53.0
TH1_k127_2317398_4 - - - - 0.00004159 53.0
TH1_k127_2318345_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0 1033.0
TH1_k127_2318345_1 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000002356 234.0
TH1_k127_2318345_2 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000001261 191.0
TH1_k127_2326496_0 Pyruvate:ferredoxin oxidoreductase core domain II K03737 - 1.2.7.1 2.105e-231 721.0
TH1_k127_2326496_1 Tetratricopeptide repeat - - - 0.00000000000000000000000003562 111.0
TH1_k127_232851_0 flagellar basal-body rod protein FlgG K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 338.0
TH1_k127_232851_1 bacterial-type flagellum organization K02279,K02386 - - 0.00000000000000000000000008765 119.0
TH1_k127_232851_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0007654 48.0
TH1_k127_2338487_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 498.0
TH1_k127_2338487_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 352.0
TH1_k127_2338487_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000005972 77.0
TH1_k127_2339708_0 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003744 281.0
TH1_k127_2339708_1 Transposase - - - 0.0000000000000000000000000000000000000000000000002701 183.0
TH1_k127_2339708_3 multidrug transporter - - - 0.0000004443 56.0
TH1_k127_2343742_0 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 460.0
TH1_k127_2343742_1 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 290.0
TH1_k127_2360836_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 2.521e-218 692.0
TH1_k127_2360836_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 300.0
TH1_k127_2360836_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 317.0
TH1_k127_2360836_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001777 284.0
TH1_k127_2360836_4 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000001204 244.0
TH1_k127_2360836_5 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000000000000000000000003687 154.0
TH1_k127_2360836_6 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000004229 103.0
TH1_k127_2360836_7 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000004436 49.0
TH1_k127_2363241_0 Polysaccharide biosynthesis protein CapD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 458.0
TH1_k127_2363241_1 PFAM NAD-dependent epimerase dehydratase K06118 - 3.13.1.1 0.000000000000000004489 84.0
TH1_k127_2366028_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 307.0
TH1_k127_2366028_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000005087 145.0
TH1_k127_2366028_2 - - - - 0.00000000008417 63.0
TH1_k127_2426507_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 314.0
TH1_k127_2426507_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 299.0
TH1_k127_2426507_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001484 269.0
TH1_k127_2426507_3 Protoglobin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001295 267.0
TH1_k127_2441777_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 8.259e-253 791.0
TH1_k127_2448863_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007225 271.0
TH1_k127_2448863_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000009103 85.0
TH1_k127_2449487_0 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 355.0
TH1_k127_2449487_1 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000007301 164.0
TH1_k127_2449487_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000003968 152.0
TH1_k127_246604_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 6.858e-280 872.0
TH1_k127_2479207_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1367.0
TH1_k127_2479207_2 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000003592 93.0
TH1_k127_2482939_0 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000000000000000000002396 216.0
TH1_k127_2482939_1 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000000000002607 144.0
TH1_k127_2482939_2 Response regulator, receiver - - - 0.00000000000000000001096 101.0
TH1_k127_2482939_3 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000000000004866 91.0
TH1_k127_2482939_4 - - - - 0.0009772 47.0
TH1_k127_2508559_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 350.0
TH1_k127_2508559_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000004768 241.0
TH1_k127_2508559_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000131 195.0
TH1_k127_2508559_3 Tim44 - - - 0.0000000000001017 76.0
TH1_k127_2512216_0 PFAM NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 443.0
TH1_k127_2512216_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 344.0
TH1_k127_2512216_2 - - - - 0.000000000038 70.0
TH1_k127_2514534_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 458.0
TH1_k127_2514534_1 oxidation-reduction process - - - 0.0000000000000000000000000009205 117.0
TH1_k127_2514534_2 amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000007363 107.0
TH1_k127_2515554_0 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 7.052e-202 636.0
TH1_k127_2515554_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 563.0
TH1_k127_2515554_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000003992 188.0
TH1_k127_2515554_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000006776 95.0
TH1_k127_2515554_7 PFAM Integrase catalytic region K07497 - - 0.00009384 47.0
TH1_k127_2519193_0 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 499.0
TH1_k127_2519193_1 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001062 260.0
TH1_k127_2519193_2 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000002348 231.0
TH1_k127_2519193_3 Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.00000000000000000001412 98.0
TH1_k127_2519193_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000001456 57.0
TH1_k127_2525423_0 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 486.0
TH1_k127_2525423_1 General secretion pathway protein K02459,K02672,K02680 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000000000000000000000000000000000000000000000000000008633 222.0
TH1_k127_2525423_2 PFAM type II secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000000000000001432 192.0
TH1_k127_2525423_3 protein transport across the cell outer membrane K02457,K08084 - - 0.00000000000000000000000000000000000023 145.0
TH1_k127_2525423_4 type IV pilus modification protein PilV K02458,K02671,K02681 - - 0.0000000000000000002384 93.0
TH1_k127_2525423_5 PFAM General secretion pathway protein K K02460 - - 0.0000000000123 68.0
TH1_k127_2529280_0 Heat shock 70 kDa protein K04043 - - 4.311e-297 916.0
TH1_k127_2529280_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000002472 179.0
TH1_k127_2529280_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000004425 121.0
TH1_k127_2529302_0 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000495 235.0
TH1_k127_2529302_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000009903 231.0
TH1_k127_2529302_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000002886 183.0
TH1_k127_2529302_3 Flp Fap pilin component K02651 - - 0.0005303 44.0
TH1_k127_2533033_0 Histidine kinase K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 451.0
TH1_k127_2533918_0 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 530.0
TH1_k127_2533918_1 PFAM Fimbrial assembly K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 369.0
TH1_k127_2545754_0 PFAM Mu-like major head subunit gpT, prophage - - - 0.0000000000000000000000000000000000000003406 152.0
TH1_k127_2545754_1 Protein of unknown function (DUF1320) - - - 0.00000000000000000000000000000002969 130.0
TH1_k127_2545754_2 Hydrolase - - - 0.00000000000001263 83.0
TH1_k127_2562911_0 PFAM MgsA AAA ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 567.0
TH1_k127_2562911_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 327.0
TH1_k127_2562911_2 THUMP - - - 0.0000000000000000000000000000000000009613 152.0
TH1_k127_2562911_3 TIGRFAM Protein of - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000006349 127.0
TH1_k127_2562911_4 Response regulator, receiver K01733,K22010 - 4.2.3.1 0.0000000000000000000000000000008324 126.0
TH1_k127_2562911_5 Sec-independent protein translocase protein TatA K03116 - - 0.000000000000000000000000002716 113.0
TH1_k127_2562911_6 Sec-independent protein translocase protein TatA K03116,K03117,K03646 - - 0.00000000000000001398 86.0
TH1_k127_2572255_0 FAD dependent oxidoreductase K16885 - - 4.376e-194 612.0
TH1_k127_2572255_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 530.0
TH1_k127_2572255_2 reductase alpha subunit K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000009238 233.0
TH1_k127_2585694_0 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 463.0
TH1_k127_2585694_1 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 392.0
TH1_k127_2585694_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000007656 241.0
TH1_k127_2585694_3 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000002071 211.0
TH1_k127_2603318_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.371e-219 705.0
TH1_k127_2603318_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0001851 48.0
TH1_k127_2663770_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003289 270.0
TH1_k127_2663770_1 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002227 237.0
TH1_k127_2663770_2 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000001374 234.0
TH1_k127_2663770_3 nickel cation binding K04651 - - 0.00000000000000000000000000008979 121.0
TH1_k127_2663770_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000002097 102.0
TH1_k127_2671025_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 634.0
TH1_k127_2671025_1 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000004859 186.0
TH1_k127_2672853_0 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 527.0
TH1_k127_2672853_1 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 286.0
TH1_k127_2672853_2 PFAM Thioredoxin K03671 - - 0.0000000000000000000000000004315 117.0
TH1_k127_2672853_3 PFAM regulatory protein, ArsR K03892 - - 0.000000000000000000000000001261 115.0
TH1_k127_26738_0 O-methyltransferase activity - - - 5.634e-202 652.0
TH1_k127_26738_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000001103 160.0
TH1_k127_2679389_0 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 329.0
TH1_k127_2679389_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 306.0
TH1_k127_2708316_0 FecR protein - - - 0.00000000000000000001919 102.0
TH1_k127_2708316_1 Tetratricopeptide repeat - - - 0.000000003839 64.0
TH1_k127_2745859_0 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000001234 109.0
TH1_k127_2754070_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 428.0
TH1_k127_2784467_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.0 1011.0
TH1_k127_2784467_1 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 609.0
TH1_k127_2784467_2 ferredoxin oxidoreductase beta subunit K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 571.0
TH1_k127_2784467_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001263 267.0
TH1_k127_2784467_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000004068 245.0
TH1_k127_2784467_5 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000003229 204.0
TH1_k127_2784467_6 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000001992 75.0
TH1_k127_2805031_0 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 521.0
TH1_k127_2805031_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 498.0
TH1_k127_2805031_2 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.00000000000003711 76.0
TH1_k127_2812249_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 415.0
TH1_k127_2812249_1 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 373.0
TH1_k127_2819639_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 495.0
TH1_k127_2819639_1 PFAM Glycosyl transferase, family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 460.0
TH1_k127_2819639_2 Rhomboid family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002602 259.0
TH1_k127_2819639_3 PFAM Tetratricopeptide repeat - - - 0.000000000000000001544 96.0
TH1_k127_2832989_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 6.67e-237 742.0
TH1_k127_2832989_1 TPR repeat - - - 0.00000000000000000000001256 109.0
TH1_k127_2850589_0 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000002191 259.0
TH1_k127_2850589_1 Protein of unknown function (DUF1614) - - - 0.000000000000000000000000000000000000000000000000000000000001797 214.0
TH1_k127_286872_0 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002286 273.0
TH1_k127_286872_1 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000003722 171.0
TH1_k127_2874178_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 513.0
TH1_k127_2874178_1 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 332.0
TH1_k127_2874178_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 306.0
TH1_k127_2874178_3 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001733 268.0
TH1_k127_2874178_4 - - - - 0.0000000000000000000000000000000000000000000000000001192 189.0
TH1_k127_2874178_5 PFAM AMMECR1 domain protein K09141 - - 0.0000000000002478 73.0
TH1_k127_2880979_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 7.809e-253 796.0
TH1_k127_2880979_1 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004604 259.0
TH1_k127_2880979_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000002077 200.0
TH1_k127_2880979_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000004868 151.0
TH1_k127_2881320_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 7.693e-303 954.0
TH1_k127_2881320_1 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000009549 117.0
TH1_k127_2884425_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 443.0
TH1_k127_2884425_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 421.0
TH1_k127_2884425_2 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.000000000000000000000000000000000000004362 160.0
TH1_k127_2884425_3 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000005171 136.0
TH1_k127_2889967_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 5.586e-218 691.0
TH1_k127_2889967_1 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 371.0
TH1_k127_2889967_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000003791 224.0
TH1_k127_2889967_3 FAD dependent oxidoreductase - - - 0.0000000000000000000000001764 106.0
TH1_k127_2889967_4 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000007202 98.0
TH1_k127_2926955_0 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 374.0
TH1_k127_2926955_1 Alpha/beta hydrolase family K07020 - - 0.0000000000000000000000000000000000000002535 157.0
TH1_k127_2926955_2 - - - - 0.000000000000000000000000000000000000462 146.0
TH1_k127_2928875_0 TIGRFAM NRAMP (natural resistance-associated macrophage protein) metal ion transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 544.0
TH1_k127_2928875_1 transporter (mgtE) K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 458.0
TH1_k127_2928875_2 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 321.0
TH1_k127_2928875_3 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000003658 271.0
TH1_k127_2931789_0 large subunit K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 463.0
TH1_k127_2931789_1 hydrogenase maturation protease K03605 - - 0.000000000000000000000004801 110.0
TH1_k127_2936402_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 366.0
TH1_k127_2936402_1 ABC transporter, permease protein K02066 - - 0.00000000000000000000000000000000000000000000000000005449 195.0
TH1_k127_2944915_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 366.0
TH1_k127_2944915_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000583 226.0
TH1_k127_2948152_0 EXOIII K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000003534 223.0
TH1_k127_2948152_1 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000003386 163.0
TH1_k127_2948152_2 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000006988 100.0
TH1_k127_2948152_3 Domain of unknown function (DUF4412) - - - 0.000000000000000000003041 101.0
TH1_k127_2948253_0 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 579.0
TH1_k127_2948253_1 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 338.0
TH1_k127_2948253_2 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000001942 205.0
TH1_k127_2948253_3 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000006005 158.0
TH1_k127_2948253_4 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000001914 89.0
TH1_k127_2958436_0 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 471.0
TH1_k127_2958436_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 455.0
TH1_k127_298404_0 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002718 243.0
TH1_k127_298404_1 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001954 235.0
TH1_k127_298404_2 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000001673 167.0
TH1_k127_298404_3 Histidine kinase - - - 0.0000000000000000000000000001691 128.0
TH1_k127_298404_4 PFAM ATP-binding region ATPase domain protein K07678 - 2.7.13.3 0.0000000000000006524 93.0
TH1_k127_298404_5 cheY-homologous receiver domain - - - 0.0000004207 62.0
TH1_k127_3005427_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 330.0
TH1_k127_3005427_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002458 242.0
TH1_k127_3005427_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000002541 164.0
TH1_k127_3005486_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000004357 225.0
TH1_k127_3005486_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000001217 193.0
TH1_k127_3005486_2 VanZ like family - - - 0.000002579 58.0
TH1_k127_3027918_0 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 434.0
TH1_k127_3027918_1 Domain of unknown function (DUF4091) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 319.0
TH1_k127_3029017_0 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002014 274.0
TH1_k127_3029017_1 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000001073 147.0
TH1_k127_3029017_2 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000003489 82.0
TH1_k127_3029017_3 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000005356 55.0
TH1_k127_3048807_0 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 457.0
TH1_k127_3048807_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 343.0
TH1_k127_3048944_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.111e-202 638.0
TH1_k127_3048944_1 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000001436 138.0
TH1_k127_3048944_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000001462 78.0
TH1_k127_3067761_0 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 392.0
TH1_k127_3067761_1 COG4448 L-asparaginase II - - - 0.00000000000000000000000000000005821 127.0
TH1_k127_3077015_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.183e-278 865.0
TH1_k127_3077015_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000002036 85.0
TH1_k127_3082442_0 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 289.0
TH1_k127_3082442_1 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000007586 199.0
TH1_k127_3082442_2 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.000000000000000000000000000000005262 137.0
TH1_k127_3094734_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 7.535e-251 788.0
TH1_k127_310631_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 467.0
TH1_k127_3148140_0 Pfam:DUF2029 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004569 249.0
TH1_k127_3148140_1 - - - - 0.0000000000000000000000000000000000000000000000000000001863 199.0
TH1_k127_3157947_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 426.0
TH1_k127_3157947_1 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 409.0
TH1_k127_3160353_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 6.97e-210 666.0
TH1_k127_3160353_1 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000007711 189.0
TH1_k127_3160353_2 ABC-type multidrug transport system ATPase K01990 - - 0.0000006521 59.0
TH1_k127_3169115_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 5.64e-197 623.0
TH1_k127_3169115_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 604.0
TH1_k127_3170069_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 299.0
TH1_k127_3170069_1 SMART Rhodanese domain protein - - - 0.000000000000000000001895 100.0
TH1_k127_3170069_2 - - - - 0.00000003778 56.0
TH1_k127_3172401_0 HlyD family secretion protein K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 429.0
TH1_k127_3172401_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003146 244.0
TH1_k127_317825_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 478.0
TH1_k127_317825_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002254 251.0
TH1_k127_3199025_0 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 381.0
TH1_k127_3220337_0 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 451.0
TH1_k127_3220337_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 421.0
TH1_k127_3220337_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 295.0
TH1_k127_3238379_0 ResB-like family K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 332.0
TH1_k127_3238379_1 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 310.0
TH1_k127_3238379_2 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000001129 185.0
TH1_k127_3238379_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000127 162.0
TH1_k127_3238379_4 COG1230 Co Zn Cd efflux system component K16264 - - 0.00000000000000000000000000000000003309 141.0
TH1_k127_3238379_5 Universal stress protein K06149 - - 0.0000000000000000000000000000006781 126.0
TH1_k127_3238379_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000532 101.0
TH1_k127_3238379_7 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000001228 102.0
TH1_k127_323987_0 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000783 251.0
TH1_k127_323987_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000001248 105.0
TH1_k127_323987_2 Polysaccharide biosynthesis protein - - - 0.0002902 47.0
TH1_k127_3240846_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.037e-286 899.0
TH1_k127_3240846_1 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 398.0
TH1_k127_3240846_2 COGs COG1150 Heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000003747 206.0
TH1_k127_3254284_0 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 473.0
TH1_k127_3254284_1 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.000000000000000003513 86.0
TH1_k127_3254284_2 LppC putative lipoprotein - - - 0.00000000000003811 78.0
TH1_k127_3289272_0 G-rich domain on putative tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 307.0
TH1_k127_3289272_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000001519 145.0
TH1_k127_3305728_0 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 575.0
TH1_k127_3305728_1 PFAM Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 290.0
TH1_k127_3305728_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000009383 240.0
TH1_k127_3305728_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000007713 201.0
TH1_k127_3305728_4 Staphylococcal nuclease homologues - - - 0.0000000000000000000000000000000000000000000000004162 183.0
TH1_k127_3305728_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000001518 142.0
TH1_k127_3313964_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 469.0
TH1_k127_3313964_1 PFAM ROSMUCR transcriptional regulator - - - 0.0000000000000000000000000000000000000000006934 161.0
TH1_k127_3332285_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.384e-266 842.0
TH1_k127_3332285_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00205,K02573,K02691 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0009579,GO:0016020,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 324.0
TH1_k127_3337917_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 612.0
TH1_k127_3337917_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 486.0
TH1_k127_3337917_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000008165 252.0
TH1_k127_3337917_3 regulatory protein, FmdB family - - - 0.00000000000000000000000000000003082 126.0
TH1_k127_3337917_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000005556 117.0
TH1_k127_33668_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 446.0
TH1_k127_33668_1 Papain family cysteine protease - - - 0.0005415 48.0
TH1_k127_3426980_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 8.508e-203 644.0
TH1_k127_3426980_1 Domain in cystathionine beta-synthase and other proteins. K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 323.0
TH1_k127_3426980_2 cytochrome c nitrate reductase, small subunit K15876 - - 0.00000000000000000000000000000000000000000000000000000002275 200.0
TH1_k127_3426980_3 Histidine kinase - - - 0.00000000000000000000000000000000000000002107 177.0
TH1_k127_3426980_4 Domain of unknown function (DUF4405) - - - 0.0000000000000000000000000000000000006719 145.0
TH1_k127_3426980_5 Late embryogenesis abundant protein - - - 0.000000000000000000000000000000000003699 143.0
TH1_k127_3426980_6 Cytochrome c - - - 0.00000000000000000000001018 106.0
TH1_k127_3434793_0 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000002329 244.0
TH1_k127_3434793_1 Rubrerythrin - - - 0.000000000000000000000000000000001089 132.0
TH1_k127_3434793_2 - - - - 0.00000000000000000001072 94.0
TH1_k127_3434793_3 AntiSigma factor - - - 0.00000000000001341 81.0
TH1_k127_3434793_4 ATP-independent chaperone mediated protein folding K07803 - - 0.0000001968 55.0
TH1_k127_3437239_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 546.0
TH1_k127_3437239_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000002821 222.0
TH1_k127_3445128_0 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 501.0
TH1_k127_3445128_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 422.0
TH1_k127_3445128_2 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000006736 106.0
TH1_k127_3448318_0 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 348.0
TH1_k127_3448318_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000006856 208.0
TH1_k127_3449659_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 595.0
TH1_k127_3449659_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 504.0
TH1_k127_3449659_2 Cysteine-rich secretory protein family - - - 0.0000000000000000001789 95.0
TH1_k127_3449659_3 - - - - 0.00001418 50.0
TH1_k127_3491030_0 PFAM Glycoside hydrolase 15-related - - - 0.0 1012.0
TH1_k127_3491561_0 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 - 2.10.1.1 1.039e-260 817.0
TH1_k127_3491561_1 Belongs to the Fur family K03711,K09825 - - 0.00000000002958 64.0
TH1_k127_3494410_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 388.0
TH1_k127_3494410_1 2 iron, 2 sulfur cluster binding K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 368.0
TH1_k127_3494410_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000002833 151.0
TH1_k127_3494410_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.00000000000000000000002972 102.0
TH1_k127_3494437_0 Protein of unknown function (DUF935) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 356.0
TH1_k127_3494437_1 PFAM Mu-like major head subunit gpT, prophage - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 295.0
TH1_k127_3494437_2 Mu-like prophage I protein - - - 0.0000000000000000000000000000000000000000000000006979 188.0
TH1_k127_3494437_3 - - - - 0.00000000000000000000000000000000002796 138.0
TH1_k127_3500524_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 372.0
TH1_k127_3500524_1 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000004684 229.0
TH1_k127_3500524_2 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000008243 188.0
TH1_k127_3500524_3 PFAM chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000001285 189.0
TH1_k127_3500524_4 snoRNA binding - - - 0.00000000004487 66.0
TH1_k127_3543302_0 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 328.0
TH1_k127_3543302_1 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.000000000000000000000000000000000000000000007075 166.0
TH1_k127_3543302_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000004057 148.0
TH1_k127_3543302_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000001963 120.0
TH1_k127_3549333_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 548.0
TH1_k127_3549333_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 439.0
TH1_k127_3549333_2 CBS domain containing protein K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 377.0
TH1_k127_3549333_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000000000000000000415 212.0
TH1_k127_3549333_4 Histidine kinase - - - 0.00004278 53.0
TH1_k127_3574635_0 NAD-dependent dehydratase - - - 0.0000000000000000000000000000000009928 132.0
TH1_k127_3574635_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000198 100.0
TH1_k127_3582364_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 325.0
TH1_k127_3582364_1 Methyltransferase type 11 K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000005348 124.0
TH1_k127_3583174_0 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 349.0
TH1_k127_3583174_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000142 295.0
TH1_k127_3583174_3 Universal stress protein family - - - 0.00000000000000000000000005226 113.0
TH1_k127_3599519_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 547.0
TH1_k127_3599519_1 PFAM UvrD REP helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 401.0
TH1_k127_3599519_2 Pfam:DUF490 K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 324.0
TH1_k127_3632164_0 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002034 273.0
TH1_k127_3632164_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000001747 246.0
TH1_k127_3642891_0 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007886 402.0
TH1_k127_3642891_1 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 286.0
TH1_k127_3642891_2 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000001911 102.0
TH1_k127_3658223_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 372.0
TH1_k127_3667721_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 4.047e-250 787.0
TH1_k127_3667721_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 534.0
TH1_k127_3667721_10 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000006024 198.0
TH1_k127_3667721_11 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000002188 177.0
TH1_k127_3667721_12 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000000000000000007011 154.0
TH1_k127_3667721_13 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000002064 136.0
TH1_k127_3667721_14 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001388 71.0
TH1_k127_3667721_15 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000005222 69.0
TH1_k127_3667721_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 503.0
TH1_k127_3667721_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 466.0
TH1_k127_3667721_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 374.0
TH1_k127_3667721_5 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 372.0
TH1_k127_3667721_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 310.0
TH1_k127_3667721_7 PFAM NLP P60 protein K19223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002726 261.0
TH1_k127_3667721_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000006501 261.0
TH1_k127_3667721_9 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000109 220.0
TH1_k127_3671828_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 489.0
TH1_k127_3671828_1 Lytic transglycosylase catalytic K08307 - - 0.00000000000000000000000000000000000000000001394 165.0
TH1_k127_3680109_0 Domain of unknown function (DUF4091) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 394.0
TH1_k127_3680109_1 - - - - 0.00000007095 66.0
TH1_k127_3689129_0 Transcriptional regulator, TetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 292.0
TH1_k127_3693227_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 594.0
TH1_k127_3693227_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 562.0
TH1_k127_3693227_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 534.0
TH1_k127_3693227_3 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000805 83.0
TH1_k127_3700441_0 Flavin containing amine oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 519.0
TH1_k127_3700441_1 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 355.0
TH1_k127_3704115_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 6.299e-205 647.0
TH1_k127_3711641_0 Pyruvate:ferredoxin oxidoreductase core domain II K03737 - 1.2.7.1 0.0 1579.0
TH1_k127_3711641_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000207 198.0
TH1_k127_3713993_0 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 297.0
TH1_k127_3713993_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001978 274.0
TH1_k127_3713993_2 PFAM MgtC SapB transporter K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005129 259.0
TH1_k127_3713993_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000002937 198.0
TH1_k127_3743923_0 PFAM Major Facilitator Superfamily K08177 - - 1.212e-215 675.0
TH1_k127_3743923_1 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 522.0
TH1_k127_3743923_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 392.0
TH1_k127_3743923_3 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000006058 198.0
TH1_k127_3759449_0 PFAM Pyruvate carboxyltransferase - - - 1.441e-299 925.0
TH1_k127_3759449_1 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.772e-287 888.0
TH1_k127_3759449_2 TIGRFAM methylmalonyl-CoA mutase C-terminal domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000004204 201.0
TH1_k127_3765960_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 556.0
TH1_k127_3765960_1 Belongs to the ClpX chaperone family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 460.0
TH1_k127_3765960_2 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 308.0
TH1_k127_3765960_3 Formiminotransferase-cyclodeaminase - - - 0.000000000000000000000000000498 123.0
TH1_k127_3825758_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 535.0
TH1_k127_3825758_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 441.0
TH1_k127_3825758_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 381.0
TH1_k127_3825758_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 341.0
TH1_k127_3825758_4 ABC transporter K01996 - - 0.0000000000005245 71.0
TH1_k127_3825758_5 Protein of unknown function DUF45 K07043 - - 0.0006611 48.0
TH1_k127_38450_0 transport system permease K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 419.0
TH1_k127_38450_1 phosphorelay sensor kinase activity K07708,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 404.0
TH1_k127_38450_2 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 373.0
TH1_k127_3849901_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 347.0
TH1_k127_3849901_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000001348 223.0
TH1_k127_3849901_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000001929 228.0
TH1_k127_3849901_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000001698 87.0
TH1_k127_3855773_0 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 460.0
TH1_k127_3855773_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 432.0
TH1_k127_3855773_2 Nucleic acid binding OB-fold tRNA helicase-type - - - 0.000000000003173 72.0
TH1_k127_3857294_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002049 281.0
TH1_k127_3857294_1 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000000000007943 233.0
TH1_k127_3857294_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000007568 223.0
TH1_k127_3857294_3 TfoX N-terminal domain K07343 - - 0.00000000000000000000000000022 118.0
TH1_k127_3857294_4 PFAM SNARE associated Golgi protein - - - 0.00000000000000000005114 91.0
TH1_k127_3857294_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000134 61.0
TH1_k127_3876252_0 Histidine kinase - - - 2.812e-203 649.0
TH1_k127_3876252_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 353.0
TH1_k127_3876252_2 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009339 239.0
TH1_k127_3876252_3 PFAM Radical SAM - - - 0.000000000000003695 76.0
TH1_k127_3876252_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000002558 61.0
TH1_k127_3879828_0 Histidine kinase K07709 - 2.7.13.3 2.02e-250 795.0
TH1_k127_3879828_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001176 277.0
TH1_k127_3879828_2 PFAM response regulator receiver - - - 0.000000000006031 66.0
TH1_k127_3897010_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 357.0
TH1_k127_3897010_1 SMART PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000001235 183.0
TH1_k127_3906751_0 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 359.0
TH1_k127_3918954_0 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 419.0
TH1_k127_3918954_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000001421 118.0
TH1_k127_3922473_0 ligase activity K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002911 255.0
TH1_k127_3922473_1 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000002044 232.0
TH1_k127_3922473_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000009163 142.0
TH1_k127_3922473_3 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) K05967 - - 0.000000000000000000000000000001225 128.0
TH1_k127_3951000_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 585.0
TH1_k127_3951000_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000001545 181.0
TH1_k127_3951000_2 - - - - 0.0000000000000000000000000000000000000000915 163.0
TH1_k127_3975062_0 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005199 281.0
TH1_k127_3975062_1 PFAM type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006456 276.0
TH1_k127_3975062_2 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000000000000000000000452 167.0
TH1_k127_3975062_3 PFAM Type II secretion system protein E K02283,K03609 - - 0.0000000000000000006486 87.0
TH1_k127_3994061_0 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001849 278.0
TH1_k127_3994061_1 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000002546 234.0
TH1_k127_3994061_2 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000000003664 220.0
TH1_k127_3998687_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 441.0
TH1_k127_4012248_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13598 - 2.7.13.3 2.353e-220 706.0
TH1_k127_4012248_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 564.0
TH1_k127_4012248_2 Histidine kinase K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 546.0
TH1_k127_4012248_3 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 342.0
TH1_k127_4016746_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 385.0
TH1_k127_4016746_1 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000001272 236.0
TH1_k127_4023004_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.651e-197 628.0
TH1_k127_4023004_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 304.0
TH1_k127_4042425_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001063 236.0
TH1_k127_4042425_1 Transcription termination factor nusG - - - 0.000000000000000000001015 96.0
TH1_k127_4072831_0 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 342.0
TH1_k127_4072831_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000003465 228.0
TH1_k127_4072831_2 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000002656 175.0
TH1_k127_4085350_0 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 372.0
TH1_k127_4085350_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 294.0
TH1_k127_4090184_0 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 1.054e-301 944.0
TH1_k127_4090184_1 pyruvate K01571,K01958,K01960 - 4.1.1.3,6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 476.0
TH1_k127_4118508_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5.314e-248 772.0
TH1_k127_4127378_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 452.0
TH1_k127_4127378_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 349.0
TH1_k127_4127378_2 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000008446 196.0
TH1_k127_4127378_3 Cyclophilin-like K09143 - - 0.00000000000000000000000000000002846 130.0
TH1_k127_4127378_4 - - - - 0.00000000000000000000000004819 115.0
TH1_k127_4127378_5 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000001771 94.0
TH1_k127_4127378_6 regulatory protein, FmdB family - - - 0.00000000000000004548 82.0
TH1_k127_4133827_0 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 293.0
TH1_k127_4133827_1 PFAM Lytic K08309 - - 0.000000000000000000000000000000000000000002318 163.0
TH1_k127_4138923_0 His Kinase A (phosphoacceptor) domain - - - 4.652e-216 683.0
TH1_k127_4138923_1 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 3.935e-209 661.0
TH1_k127_4138923_2 Histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 313.0
TH1_k127_4150765_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 8.536e-262 821.0
TH1_k127_4150765_1 PFAM Radical SAM K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 509.0
TH1_k127_4150765_2 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 379.0
TH1_k127_4150765_3 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 287.0
TH1_k127_4150765_4 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000000000002737 186.0
TH1_k127_4170839_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 5.391e-218 679.0
TH1_k127_4170839_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000005069 201.0
TH1_k127_4195921_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 443.0
TH1_k127_4195921_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 353.0
TH1_k127_4195921_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000008031 224.0
TH1_k127_4195921_3 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000001205 186.0
TH1_k127_4213926_0 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.00000000000000000000000000000000000000000000000000000000001791 212.0
TH1_k127_4213926_2 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000002692 129.0
TH1_k127_4213926_3 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000008191 104.0
TH1_k127_4213926_4 PFAM Methylamine - - - 0.00000000000000000000005777 108.0
TH1_k127_4232039_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 547.0
TH1_k127_4232039_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000001787 110.0
TH1_k127_4232039_2 - - - - 0.000000000000000002453 87.0
TH1_k127_4232039_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000001839 83.0
TH1_k127_4239176_0 transmembrane signaling receptor activity K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002638 293.0
TH1_k127_4239176_1 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000009064 242.0
TH1_k127_4239176_2 PFAM chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000001191 233.0
TH1_k127_4239176_3 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000002104 199.0
TH1_k127_4239176_4 CheR methyltransferase, SAM binding domain K00575 - 2.1.1.80 0.000000000000000000000000000000000004803 144.0
TH1_k127_4261794_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 3.367e-201 634.0
TH1_k127_4261794_1 - - - - 0.0005777 48.0
TH1_k127_4273602_0 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000002369 221.0
TH1_k127_4286607_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 5.263e-228 728.0
TH1_k127_4286607_1 amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 400.0
TH1_k127_4286607_2 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000356 219.0
TH1_k127_4286607_3 coenzyme F420 binding K00275 - 1.4.3.5 0.0000000000000000000000000000000000000001429 157.0
TH1_k127_4289730_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 440.0
TH1_k127_4289730_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002901 284.0
TH1_k127_4308541_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 6.209e-254 801.0
TH1_k127_4308541_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000844 204.0
TH1_k127_4311994_0 Biotin carboxylase C-terminal domain K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 6.577e-208 656.0
TH1_k127_4311994_1 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 467.0
TH1_k127_4311994_2 pyruvate K01571,K01958,K01960 - 4.1.1.3,6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 410.0
TH1_k127_4318950_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001182 275.0
TH1_k127_4318950_1 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000001124 267.0
TH1_k127_4318950_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000002658 163.0
TH1_k127_4318950_3 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000004007 119.0
TH1_k127_4325073_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 439.0
TH1_k127_4337991_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 355.0
TH1_k127_4337991_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000001874 68.0
TH1_k127_4351292_0 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000002156 230.0
TH1_k127_4351292_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000004464 153.0
TH1_k127_4351292_2 Chemotaxis phosphatase, CheZ - - - 0.000000000000000000000000000003398 133.0
TH1_k127_4365105_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 494.0
TH1_k127_4365105_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000001442 111.0
TH1_k127_4368093_0 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008199 286.0
TH1_k127_4368093_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002109 265.0
TH1_k127_4368093_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000003276 161.0
TH1_k127_4368093_3 Glycosyltransferases involved in cell wall biogenesis K20444 - - 0.000000000000000000000000006419 117.0
TH1_k127_4368093_4 Evidence 5 No homology to any previously reported sequences K01991,K02557,K07161,K07484,K13924,K20444,K21471 - 2.1.1.80,3.1.1.61 0.000000000000196 79.0
TH1_k127_4383019_0 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 332.0
TH1_k127_4383019_1 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 326.0
TH1_k127_4383019_2 DNA polymerase X family K02347 - - 0.00000000000000000000000000000000000000000241 163.0
TH1_k127_4383019_3 O-methyltransferase activity - - - 0.00000004705 55.0
TH1_k127_4394079_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 557.0
TH1_k127_4394079_1 Domain of unknown function (DUF4301) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 485.0
TH1_k127_4394079_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 373.0
TH1_k127_4404212_0 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 482.0
TH1_k127_4404212_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000003012 248.0
TH1_k127_4424109_0 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 295.0
TH1_k127_4424109_1 protein trimerization - - - 0.0000000000000000000000000002434 118.0
TH1_k127_442565_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 426.0
TH1_k127_442565_1 Heavy-metal-associated domain K07213 - - 0.00008226 45.0
TH1_k127_4426660_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1028.0
TH1_k127_4426660_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 356.0
TH1_k127_4426660_2 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 314.0
TH1_k127_4439791_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 391.0
TH1_k127_4439791_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 349.0
TH1_k127_4439791_2 PFAM ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 334.0
TH1_k127_4439791_3 MlaD protein K02067 - - 0.000000000000000001197 87.0
TH1_k127_4443931_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 536.0
TH1_k127_4443931_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 496.0
TH1_k127_4443931_2 PFAM ABC transporter K01990 - - 0.000000000000000000000000009453 113.0
TH1_k127_4443931_3 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.000000000000000000006394 100.0
TH1_k127_4450398_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 593.0
TH1_k127_4450398_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008646 283.0
TH1_k127_4450398_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000004624 225.0
TH1_k127_4450398_3 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000004017 153.0
TH1_k127_4461500_0 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 290.0
TH1_k127_4461500_1 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000005075 214.0
TH1_k127_4461500_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000268 173.0
TH1_k127_4461500_3 - - - - 0.00000000000001291 75.0
TH1_k127_4468984_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 415.0
TH1_k127_4468984_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 289.0
TH1_k127_4468984_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000005673 234.0
TH1_k127_4501346_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 336.0
TH1_k127_4501346_1 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 305.0
TH1_k127_4501346_2 Putative regulatory protein - - - 0.0000000000339 65.0
TH1_k127_4506490_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 566.0
TH1_k127_4506490_1 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.00000000006736 65.0
TH1_k127_4506490_2 Protein of unknown function DUF86 - - - 0.000009793 48.0
TH1_k127_4527020_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 580.0
TH1_k127_4527020_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000007751 241.0
TH1_k127_4539410_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 291.0
TH1_k127_4539410_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000146 274.0
TH1_k127_455782_0 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 4.383e-283 889.0
TH1_k127_455782_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 470.0
TH1_k127_455782_2 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000001482 183.0
TH1_k127_455782_3 - - - - 0.0000000000000000000000000000001921 127.0
TH1_k127_45748_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 9.601e-304 970.0
TH1_k127_45748_1 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 452.0
TH1_k127_45748_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000003287 224.0
TH1_k127_45748_3 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000005607 96.0
TH1_k127_45748_4 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.00000000000000001564 85.0
TH1_k127_4596803_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 598.0
TH1_k127_4596803_1 thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 368.0
TH1_k127_4596803_2 thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 276.0
TH1_k127_4656248_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1100.0
TH1_k127_4656248_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 443.0
TH1_k127_4656248_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 343.0
TH1_k127_4656248_3 Acyl transferase domain - - - 0.00000001634 57.0
TH1_k127_4656248_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00006446 47.0
TH1_k127_4681004_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.689e-214 678.0
TH1_k127_4686756_0 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 390.0
TH1_k127_4686756_1 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 367.0
TH1_k127_4698834_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 565.0
TH1_k127_4698834_1 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 351.0
TH1_k127_4698834_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008746 269.0
TH1_k127_4698834_3 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000005868 157.0
TH1_k127_4698834_4 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000002804 139.0
TH1_k127_4698834_5 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000002271 128.0
TH1_k127_4703066_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 589.0
TH1_k127_4703066_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 428.0
TH1_k127_4703066_2 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000001621 108.0
TH1_k127_4704029_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 4.538e-257 811.0
TH1_k127_4704029_1 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000007621 227.0
TH1_k127_4704029_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000006458 60.0
TH1_k127_4711428_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 449.0
TH1_k127_4711428_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 299.0
TH1_k127_4711428_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 293.0
TH1_k127_4711428_3 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001897 177.0
TH1_k127_4711428_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000005534 156.0
TH1_k127_4711428_5 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000297 152.0
TH1_k127_4711428_6 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000009817 132.0
TH1_k127_4711428_7 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000008496 91.0
TH1_k127_4711428_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000006926 77.0
TH1_k127_4720129_0 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 575.0
TH1_k127_4720129_1 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 422.0
TH1_k127_4720129_2 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 316.0
TH1_k127_4720129_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005591 238.0
TH1_k127_4720129_4 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000414 198.0
TH1_k127_4724465_0 PFAM Glycosyl transferase, family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 368.0
TH1_k127_4727398_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 535.0
TH1_k127_4727398_1 COGs COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 319.0
TH1_k127_4779625_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.399e-292 913.0
TH1_k127_4779625_1 PFAM Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000002632 178.0
TH1_k127_4792006_0 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000007797 211.0
TH1_k127_4792006_1 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000001202 158.0
TH1_k127_4792006_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000002026 87.0
TH1_k127_4792006_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000002188 75.0
TH1_k127_4812629_0 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 528.0
TH1_k127_4812629_1 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 452.0
TH1_k127_4813652_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 8.221e-246 769.0
TH1_k127_4813652_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000002958 201.0
TH1_k127_4813652_2 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000003135 148.0
TH1_k127_4813652_3 Outer membrane efflux protein - - - 0.00000007387 59.0
TH1_k127_4823109_0 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' - - - 0.0000000000000000000000000000000000000000000000000000000000000000000108 255.0
TH1_k127_4823109_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000004558 188.0
TH1_k127_4852383_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 306.0
TH1_k127_4852383_1 TIGRFAM Flagellar hook-associated protein, FlgK K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 312.0
TH1_k127_4852383_2 Bacterial flagellin N-terminal helical region K02397 - - 0.0000000000000000000001664 110.0
TH1_k127_4852383_3 FliW protein K13626 - - 0.0000000000000000008664 90.0
TH1_k127_4852383_4 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000000001307 90.0
TH1_k127_4852383_5 COG3951 Rod binding protein K02395 GO:0001539,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.00001151 55.0
TH1_k127_4860954_0 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 512.0
TH1_k127_4860954_1 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000008976 177.0
TH1_k127_4860954_2 NhaP-type Na H and K H - - - 0.0000000000000000000000000000000000000000000001008 169.0
TH1_k127_4860954_3 PFAM Tetratricopeptide repeat - - - 0.00000000000000002745 85.0
TH1_k127_4860954_4 DNA integration - - - 0.00000001223 57.0
TH1_k127_4881469_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 391.0
TH1_k127_4881469_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 304.0
TH1_k127_4890908_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 374.0
TH1_k127_4890908_1 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000001008 185.0
TH1_k127_4890908_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000001764 177.0
TH1_k127_4890908_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000004636 155.0
TH1_k127_4890908_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000005509 135.0
TH1_k127_4893560_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 434.0
TH1_k127_4893560_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 305.0
TH1_k127_4893560_2 PFAM HhH-GPD superfamily base excision DNA repair protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001487 272.0
TH1_k127_4893560_3 OmpA family - - - 0.0000001128 61.0
TH1_k127_4895111_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 393.0
TH1_k127_4895111_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 385.0
TH1_k127_4895111_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 324.0
TH1_k127_4895111_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003688 285.0
TH1_k127_4895111_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003391 253.0
TH1_k127_4895111_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000002768 219.0
TH1_k127_4895111_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000002566 181.0
TH1_k127_4895111_7 YGGT family K02221 - - 0.00000000000000000000000000000001094 130.0
TH1_k127_4895111_8 DUF167 K09131 - - 0.000000000000000000003856 103.0
TH1_k127_4906677_0 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 500.0
TH1_k127_4919771_0 BadF BadG BcrA BcrD - - - 0.0 1020.0
TH1_k127_4919771_1 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000003521 172.0
TH1_k127_4935277_0 Signal transduction response regulator, receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 337.0
TH1_k127_4935277_1 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000004122 216.0
TH1_k127_4935277_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000003414 201.0
TH1_k127_4935541_0 TIGRFAM leucyl-tRNA synthetase K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1185.0
TH1_k127_4935541_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 294.0
TH1_k127_4935541_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000003886 199.0
TH1_k127_4935541_4 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000008976 92.0
TH1_k127_4935541_5 PFAM glycosyl transferase family 2 - - - 0.0007318 42.0
TH1_k127_4936402_0 sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 571.0
TH1_k127_4936402_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 488.0
TH1_k127_4936402_2 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 298.0
TH1_k127_4936402_3 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000002064 193.0
TH1_k127_4936402_4 PFAM Uncharacterised protein family UPF0066 K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000006648 171.0
TH1_k127_4936402_5 Flp Fap pilin component K02651 - - 0.000002218 51.0
TH1_k127_4943536_0 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 351.0
TH1_k127_4945955_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 500.0
TH1_k127_4945955_1 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 301.0
TH1_k127_4945955_2 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.0006574 46.0
TH1_k127_4963659_0 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 604.0
TH1_k127_4963659_1 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 322.0
TH1_k127_4963659_2 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 290.0
TH1_k127_4963659_3 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000002817 191.0
TH1_k127_4963659_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000000003853 170.0
TH1_k127_4963659_5 PFAM ABC transporter K02065 - - 0.0000000000000000000000000000000000000004341 150.0
TH1_k127_4963659_6 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000251 146.0
TH1_k127_4963659_7 Thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000002415 149.0
TH1_k127_4970120_0 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 459.0
TH1_k127_4983926_0 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 527.0
TH1_k127_4983926_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 415.0
TH1_k127_4983926_2 Phosphoesterase RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 377.0
TH1_k127_4983926_3 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 383.0
TH1_k127_4983926_4 response to heat K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 307.0
TH1_k127_4983926_5 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.00000000000000000000000000000000000000000000000165 178.0
TH1_k127_4983926_6 PFAM flagellar protein FliS K02422 - - 0.00000000000000000000000001486 114.0
TH1_k127_4983926_7 - - - - 0.000000000000006917 81.0
TH1_k127_4990772_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1238.0
TH1_k127_4990772_1 PFAM Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000004234 136.0
TH1_k127_4990772_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0007427 42.0
TH1_k127_4997823_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 363.0
TH1_k127_4997823_1 PFAM dihydropteroate synthase, DHPS K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000005349 243.0
TH1_k127_4997823_2 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000423 194.0
TH1_k127_4997823_3 Sugar phosphate permease K02445 - - 0.00000000000000000000000000000000000001128 153.0
TH1_k127_5032241_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 558.0
TH1_k127_5032241_1 Thiamine-phosphate synthase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 506.0
TH1_k127_5032241_2 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 320.0
TH1_k127_5032241_3 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000007794 138.0
TH1_k127_5035638_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 575.0
TH1_k127_5035638_1 signal-transduction protein with CBS domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 367.0
TH1_k127_5035638_2 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 353.0
TH1_k127_5035638_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000006252 221.0
TH1_k127_5035638_4 2 iron, 2 sulfur cluster binding K02823 - - 0.0000000000000000000000000000000000000000000000000021 184.0
TH1_k127_5035638_5 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000008189 97.0
TH1_k127_5035638_6 isomerase activity K01821 - 5.3.2.6 0.000000000008742 67.0
TH1_k127_5041355_0 type II secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 520.0
TH1_k127_5041355_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000005458 225.0
TH1_k127_5041355_2 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000000000000000000007435 216.0
TH1_k127_5041355_3 Type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000000003092 194.0
TH1_k127_5041355_4 Secretion system protein K12511 - - 0.00000000000000000000000000000000000000000002931 174.0
TH1_k127_5041355_5 PFAM TadE family protein - - - 0.0000000000000000000007727 108.0
TH1_k127_5041355_6 Domain of unknown function (DUF3786) - - - 0.0000000003601 61.0
TH1_k127_5041355_7 LytR cell envelope-related transcriptional attenuator - - - 0.00000001166 68.0
TH1_k127_5050788_0 TIGRFAM SagB-type dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001756 284.0
TH1_k127_5050788_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003822 267.0
TH1_k127_5050788_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000001734 238.0
TH1_k127_5050788_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000001864 234.0
TH1_k127_5050788_4 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000857 65.0
TH1_k127_5050788_5 Histidine kinase-like ATPase domain - - - 0.0007132 48.0
TH1_k127_507135_0 class II (D, K and N) K01893 - 6.1.1.22 5.126e-202 636.0
TH1_k127_5082414_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.678e-204 648.0
TH1_k127_5082414_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001773 276.0
TH1_k127_5103589_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 7.555e-312 977.0
TH1_k127_5104928_0 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 489.0
TH1_k127_5104928_1 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 439.0
TH1_k127_5104928_2 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000008511 200.0
TH1_k127_5104928_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000003032 176.0
TH1_k127_510501_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 465.0
TH1_k127_5107707_0 Cytochrome c - - - 4.247e-248 772.0
TH1_k127_5107707_1 pfam php K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000557 181.0
TH1_k127_5121375_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 431.0
TH1_k127_5121375_2 Glycine-zipper domain - - - 0.0000000000000000008274 89.0
TH1_k127_512688_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 490.0
TH1_k127_512688_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001991 261.0
TH1_k127_512688_2 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000005555 201.0
TH1_k127_512688_3 Jag_N K06346 - - 0.000000000000000000005015 93.0
TH1_k127_5165246_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 529.0
TH1_k127_5165246_1 PFAM Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 482.0
TH1_k127_5165246_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000008047 109.0
TH1_k127_5173058_0 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007311 283.0
TH1_k127_5173058_1 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000001711 188.0
TH1_k127_5188965_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 5.822e-247 786.0
TH1_k127_5188965_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 570.0
TH1_k127_5188965_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000007538 221.0
TH1_k127_5188965_3 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.00000000001411 69.0
TH1_k127_5188965_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000001775 61.0
TH1_k127_5189632_0 Elongation factor Tu domain 2 K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 505.0
TH1_k127_5189632_1 - - - - 0.00000000000000127 80.0
TH1_k127_5189862_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002389 280.0
TH1_k127_5189862_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000445 212.0
TH1_k127_5189862_2 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000005013 184.0
TH1_k127_5231321_0 Glutamine phosphoribosylpyrophosphate amidotransferase K00764 - 2.4.2.14 1.314e-243 758.0
TH1_k127_5231321_1 PFAM Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 456.0
TH1_k127_5231684_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 468.0
TH1_k127_5238449_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1250.0
TH1_k127_5238449_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 361.0
TH1_k127_5238449_2 NIL - - - 0.0000000000000000000000000000000000000000000008478 171.0
TH1_k127_5238449_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000001594 170.0
TH1_k127_527470_0 PFAM Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 572.0
TH1_k127_527470_1 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 542.0
TH1_k127_5287731_0 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 333.0
TH1_k127_5287731_1 Flagellar Motor Protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000009175 237.0
TH1_k127_5287731_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000001645 111.0
TH1_k127_5302926_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 436.0
TH1_k127_5302926_1 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 307.0
TH1_k127_5302926_2 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000005638 205.0
TH1_k127_5302926_3 PFAM FecR protein - - - 0.00000006601 63.0
TH1_k127_5323315_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1140.0
TH1_k127_5323315_1 7TM-HD extracellular K07037 - - 4.065e-236 754.0
TH1_k127_5323315_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.326e-219 691.0
TH1_k127_5323315_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 499.0
TH1_k127_5323315_4 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 464.0
TH1_k127_5323315_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 297.0
TH1_k127_5323315_6 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000009234 163.0
TH1_k127_5323315_7 unfolded protein binding K06142 - - 0.0000000000000000000000114 106.0
TH1_k127_5326392_0 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 407.0
TH1_k127_5326392_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000001224 188.0
TH1_k127_5333661_0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 406.0
TH1_k127_5333661_1 PFAM Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 290.0
TH1_k127_5333661_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000001101 205.0
TH1_k127_5333661_3 - - - - 0.00000000000000000000000000000000000000000000000004247 185.0
TH1_k127_5333661_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000009602 176.0
TH1_k127_5333661_5 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K22491 - - 0.0000000000000000000000006103 106.0
TH1_k127_5333661_6 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.00000000000000000001139 91.0
TH1_k127_5353343_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 5.009e-222 700.0
TH1_k127_5353343_1 PFAM molybdopterin oxidoreductase Fe4S4 region - - - 0.0000000000000000000000000000000000000000000000000000001641 197.0
TH1_k127_5353343_2 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000000000000003223 147.0
TH1_k127_5353343_3 - - - - 0.00000003936 61.0
TH1_k127_5354807_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 9.83e-257 800.0
TH1_k127_5387230_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 293.0
TH1_k127_5387230_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003048 278.0
TH1_k127_5387230_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000003591 209.0
TH1_k127_5415939_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 438.0
TH1_k127_5415939_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000006371 250.0
TH1_k127_542976_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 4.746e-280 878.0
TH1_k127_542976_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000000000000000000000000000000003776 153.0
TH1_k127_542976_2 - - - - 0.000000000000000000000000000001591 122.0
TH1_k127_5441059_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003006 285.0
TH1_k127_5441059_1 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000003438 193.0
TH1_k127_5441059_2 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.0000000000000000000000000000000009833 146.0
TH1_k127_5441059_3 - - - - 0.000000145 54.0
TH1_k127_5452364_0 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000006579 147.0
TH1_k127_5452364_1 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000004745 80.0
TH1_k127_5462218_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 315.0
TH1_k127_5462218_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000001001 230.0
TH1_k127_5462218_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000005998 178.0
TH1_k127_5462218_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000118 87.0
TH1_k127_5462218_4 monooxygenase activity - - - 0.000000000000000181 81.0
TH1_k127_5472738_0 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 359.0
TH1_k127_5472738_1 Phosphorylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000006415 229.0
TH1_k127_5472738_2 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000009052 186.0
TH1_k127_5495484_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.28e-201 632.0
TH1_k127_5495484_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 337.0
TH1_k127_5495484_2 DisA bacterial checkpoint controller nucleotide-binding K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000001577 217.0
TH1_k127_5533795_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.927e-301 929.0
TH1_k127_5533795_1 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 452.0
TH1_k127_5533795_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005839 259.0
TH1_k127_5533795_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000023 186.0
TH1_k127_5533795_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000004846 156.0
TH1_k127_5543293_0 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000002385 231.0
TH1_k127_5543293_1 PFAM NUDIX domain - - - 0.0000000000000000000000000000000000000002726 154.0
TH1_k127_5623336_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 466.0
TH1_k127_5623336_1 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 439.0
TH1_k127_5623336_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 429.0
TH1_k127_5623336_3 Glycoprotease family K01409,K14742 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000771 185.0
TH1_k127_5623626_0 Pyridine nucleotide-disulphide oxidoreductase K15022 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 567.0
TH1_k127_5640731_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 362.0
TH1_k127_5640731_1 Dodecin K09165 - - 0.00000000000000000000000368 102.0
TH1_k127_5640731_2 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.000000002124 62.0
TH1_k127_5644041_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 9.239e-234 736.0
TH1_k127_5646451_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 528.0
TH1_k127_5646451_1 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 382.0
TH1_k127_5646451_2 Protein of unknown function (DUF429) - - - 0.0000000000000000000000000003006 119.0
TH1_k127_5646451_3 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.0000000000000000016 86.0
TH1_k127_5679966_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 380.0
TH1_k127_5679966_1 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000004104 163.0
TH1_k127_5679966_3 PFAM NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000004904 51.0
TH1_k127_5694806_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 439.0
TH1_k127_5694806_1 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000000000000000000000000000000002434 222.0
TH1_k127_5694806_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000004026 208.0
TH1_k127_5694806_3 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000001245 107.0
TH1_k127_5694806_4 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000001167 98.0
TH1_k127_5694806_5 Transglutaminase-like superfamily - - - 0.00000000000000002405 87.0
TH1_k127_5694806_6 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00001458 51.0
TH1_k127_5697674_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 582.0
TH1_k127_5697674_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 372.0
TH1_k127_5697674_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 319.0
TH1_k127_5697674_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000005151 215.0
TH1_k127_5697674_4 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.0000002893 63.0
TH1_k127_5697674_5 Carboxypeptidase regulatory-like domain - - - 0.0006148 46.0
TH1_k127_5716123_0 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 570.0
TH1_k127_5716123_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 329.0
TH1_k127_5716123_2 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 318.0
TH1_k127_5724629_0 Glutamine phosphoribosylpyrophosphate amidotransferase K00764 - 2.4.2.14 1.386e-241 755.0
TH1_k127_5724629_1 Gram-negative-bacterium-type cell wall biogenesis - GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564 - 0.0000000000000000000000000000003959 129.0
TH1_k127_5727687_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.948e-257 805.0
TH1_k127_5731039_0 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 448.0
TH1_k127_5731039_1 CoA binding domain K09181 - - 0.0000000002481 61.0
TH1_k127_575121_0 PFAM sigma-54 factor interaction domain-containing protein K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 376.0
TH1_k127_575121_1 bacterial-type flagellum-dependent cell motility K02387,K02388 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009425,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00000006417 56.0
TH1_k127_5762079_0 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008812 283.0
TH1_k127_5762079_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000184 250.0
TH1_k127_5766354_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 317.0
TH1_k127_5766354_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005324 286.0
TH1_k127_5766354_2 YsiA-like protein, C-terminal region K13770 - - 0.000000000000002317 84.0
TH1_k127_5774560_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 422.0
TH1_k127_5774560_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000006704 151.0
TH1_k127_5781555_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 291.0
TH1_k127_5781555_2 3D domain protein K21471 - - 0.000000000000000000000000006893 113.0
TH1_k127_5781555_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000001077 60.0
TH1_k127_5792404_0 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008234 259.0
TH1_k127_581000_0 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 295.0
TH1_k127_581000_1 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000004183 182.0
TH1_k127_584654_0 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 406.0
TH1_k127_584654_1 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000000000001291 222.0
TH1_k127_584654_2 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000000000000000000000000000000000000002463 209.0
TH1_k127_5859741_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 295.0
TH1_k127_5859741_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000005353 246.0
TH1_k127_5859741_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000006992 162.0
TH1_k127_5859741_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000003672 138.0
TH1_k127_5859741_4 Belongs to the UPF0109 family K06960 - - 0.00000004314 55.0
TH1_k127_5859779_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.384e-222 698.0
TH1_k127_5859779_1 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 407.0
TH1_k127_5859779_2 PFAM Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002982 267.0
TH1_k127_5859779_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000008426 109.0
TH1_k127_5864664_0 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 344.0
TH1_k127_5864664_1 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000001257 208.0
TH1_k127_5864664_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000002998 199.0
TH1_k127_5864664_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000006012 132.0
TH1_k127_5896610_0 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 346.0
TH1_k127_5896610_1 - - - - 0.0000000000000000000000000000000000000000000000000001351 191.0
TH1_k127_5896610_2 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000002564 152.0
TH1_k127_5897142_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 347.0
TH1_k127_5897142_1 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 296.0
TH1_k127_5897142_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000714 257.0
TH1_k127_5897142_3 - - - - 0.00000223 53.0
TH1_k127_591213_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.821e-243 758.0
TH1_k127_591213_1 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000001349 174.0
TH1_k127_5936838_0 Cytochrome c554 and c-prime - - - 3.621e-270 846.0
TH1_k127_5976299_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 549.0
TH1_k127_5976299_1 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000002339 250.0
TH1_k127_5994016_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 409.0
TH1_k127_5994016_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000001774 186.0
TH1_k127_5994016_2 - - - - 0.00000000000000001674 92.0
TH1_k127_5994016_3 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.0000003772 53.0
TH1_k127_6050392_0 CoA-transferase family III - - - 2.778e-246 766.0
TH1_k127_6050392_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 541.0
TH1_k127_6050392_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 411.0
TH1_k127_6050392_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 281.0
TH1_k127_6050392_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009428 267.0
TH1_k127_6050392_5 - - - - 0.000000000000000000000000000000000000000000000000000000000676 205.0
TH1_k127_6050392_6 - - - - 0.00000000000000000000000000000001003 127.0
TH1_k127_6050392_7 phosphorelay signal transduction system - - - 0.000000000000000000000005213 107.0
TH1_k127_6067253_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 399.0
TH1_k127_6067253_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 302.0
TH1_k127_6067253_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000002542 190.0
TH1_k127_6067253_3 ATP-independent chaperone mediated protein folding K07803 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897 - 0.00000000000000000000000005673 114.0
TH1_k127_6080490_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 503.0
TH1_k127_6080490_1 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000005007 208.0
TH1_k127_6084580_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 5.926e-258 805.0
TH1_k127_6132265_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.868e-269 833.0
TH1_k127_6132265_1 - - - - 0.000000000000007932 82.0
TH1_k127_6205228_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.0 1112.0
TH1_k127_6205228_1 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000000000000000002482 114.0
TH1_k127_6211732_0 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 315.0
TH1_k127_6211732_1 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000273 106.0
TH1_k127_6211732_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000002259 98.0
TH1_k127_6211732_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000003006 71.0
TH1_k127_6211732_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000003547 66.0
TH1_k127_6232288_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 374.0
TH1_k127_6232288_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 298.0
TH1_k127_6232288_2 PFAM Radical SAM domain protein - - - 0.00000000000000000000000002571 110.0
TH1_k127_633307_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 448.0
TH1_k127_633307_1 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001232 266.0
TH1_k127_633307_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000009673 168.0
TH1_k127_6343189_0 cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 293.0
TH1_k127_6343189_1 - - - - 0.00000000000000000000000001101 116.0
TH1_k127_6343810_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.0 1151.0
TH1_k127_6343810_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 8.602e-279 870.0
TH1_k127_6343810_2 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 495.0
TH1_k127_6343810_3 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 405.0
TH1_k127_6343810_4 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 299.0
TH1_k127_6343810_5 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000003505 233.0
TH1_k127_6343810_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000009276 190.0
TH1_k127_6343810_7 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000001367 178.0
TH1_k127_6361129_0 PFAM Polysaccharide export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004849 260.0
TH1_k127_6361129_1 Protein kinase domain - - - 0.0000000003264 73.0
TH1_k127_6365710_0 DHH family K07462 - - 1.886e-198 634.0
TH1_k127_6365710_1 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 304.0
TH1_k127_6365710_2 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000000000000000000001291 215.0
TH1_k127_6365710_3 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000003211 212.0
TH1_k127_6365710_4 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000007279 213.0
TH1_k127_6368172_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001968 283.0
TH1_k127_6368172_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000009045 141.0
TH1_k127_6369595_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 436.0
TH1_k127_6369595_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.00000006323 55.0
TH1_k127_6376349_0 SMART Elongator protein 3 MiaB NifB - - - 1.07e-252 794.0
TH1_k127_6376349_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000003909 171.0
TH1_k127_6377746_0 ABC transporter substrate binding protein K01989,K05832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003939 259.0
TH1_k127_6377746_1 Peptidase S24-like K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000001433 163.0
TH1_k127_6380402_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 469.0
TH1_k127_6380402_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 393.0
TH1_k127_6380402_2 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 342.0
TH1_k127_6380402_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 321.0
TH1_k127_6380402_4 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 301.0
TH1_k127_6380402_5 cellulase activity - - - 0.0002209 47.0
TH1_k127_6410396_0 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 580.0
TH1_k127_6410396_1 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001225 152.0
TH1_k127_6410396_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000000000004065 143.0
TH1_k127_6410396_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000006572 117.0
TH1_k127_6458809_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 481.0
TH1_k127_6458809_1 Protein of unknown function (DUF1641) - - - 0.000000000000000000000000000000000000000000005266 175.0
TH1_k127_6458809_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000008779 131.0
TH1_k127_6458809_3 Protein of unknown function, DUF599 - - - 0.00000000000000000000000000002447 121.0
TH1_k127_6458809_4 signal-transduction protein with CBS domains - - - 0.00000000000000000001062 92.0
TH1_k127_6477203_0 COG4448 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 341.0
TH1_k127_6477203_1 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 280.0
TH1_k127_647858_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 564.0
TH1_k127_6486195_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.13e-285 899.0
TH1_k127_6486195_1 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 298.0
TH1_k127_6486195_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009898 257.0
TH1_k127_6486195_3 PFAM molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.00000000000000931 74.0
TH1_k127_6497593_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000001196 262.0
TH1_k127_6497593_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000003441 211.0
TH1_k127_6497593_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000001305 174.0
TH1_k127_6497593_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000001387 159.0
TH1_k127_6508555_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 1.984e-266 837.0
TH1_k127_6519777_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 469.0
TH1_k127_6519777_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 288.0
TH1_k127_6519777_2 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 286.0
TH1_k127_6519777_3 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0007745 42.0
TH1_k127_6527525_0 Peptidase family U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 560.0
TH1_k127_6527525_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 348.0
TH1_k127_6527525_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000006457 196.0
TH1_k127_6527525_3 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000007192 193.0
TH1_k127_6559851_0 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 365.0
TH1_k127_6559851_1 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000001634 172.0
TH1_k127_6561735_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000199 264.0
TH1_k127_6561735_1 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002086 261.0
TH1_k127_6561735_3 Rubredoxin - - - 0.000001265 51.0
TH1_k127_6562565_0 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 419.0
TH1_k127_6562565_1 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 387.0
TH1_k127_6562565_2 PP-loop superfamily ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002346 267.0
TH1_k127_6562565_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000009132 224.0
TH1_k127_6562565_4 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000006365 198.0
TH1_k127_6562565_5 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000001218 201.0
TH1_k127_6562565_6 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000707 208.0
TH1_k127_6562565_7 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000785 134.0
TH1_k127_6562565_9 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000048 55.0
TH1_k127_6660090_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 437.0
TH1_k127_6660090_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 310.0
TH1_k127_6660090_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 291.0
TH1_k127_6663879_0 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 546.0
TH1_k127_6663879_1 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 332.0
TH1_k127_6663879_11 - - - - 0.0000000000001806 74.0
TH1_k127_6663879_2 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008687 322.0
TH1_k127_6663879_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 314.0
TH1_k127_6663879_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000878 253.0
TH1_k127_6663879_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000001406 203.0
TH1_k127_6663879_6 SMART PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000003148 197.0
TH1_k127_6663879_7 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000007595 162.0
TH1_k127_6663879_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000006967 134.0
TH1_k127_6663879_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000002125 132.0
TH1_k127_6676175_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000001159 175.0
TH1_k127_6676700_0 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 479.0
TH1_k127_6676700_1 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000002161 203.0
TH1_k127_6692293_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 7.328e-300 928.0
TH1_k127_6692293_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 299.0
TH1_k127_6752593_0 PFAM 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 605.0
TH1_k127_6752593_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 429.0
TH1_k127_6810470_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 558.0
TH1_k127_6810470_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000002766 230.0
TH1_k127_6810738_0 TIGRFAM capsular exopolysaccharide family K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 545.0
TH1_k127_6810738_1 PFAM Polysaccharide export protein K01991 - - 0.0000000000000000000009449 98.0
TH1_k127_6816396_0 SAF K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000008417 228.0
TH1_k127_6816396_1 response to heat K03696 - - 0.0000000000000000000000000000001126 129.0
TH1_k127_6816396_2 AAA domain K02282 - - 0.000000000000000000000000006572 117.0
TH1_k127_6816396_3 PFAM TadE family protein - - - 0.000000000000000000008602 103.0
TH1_k127_6816396_4 PFAM Flp Fap pilin component K02651 - - 0.0000000006291 61.0
TH1_k127_6817672_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 1.922e-231 723.0
TH1_k127_6817672_1 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 346.0
TH1_k127_6817672_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 309.0
TH1_k127_6817672_3 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000002 207.0
TH1_k127_6817672_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000004977 183.0
TH1_k127_6817672_5 ThiS family K03154 - - 0.00001077 50.0
TH1_k127_6822142_0 PFAM NADH ubiquinone K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 374.0
TH1_k127_6822142_1 PFAM nickel-dependent hydrogenase large subunit K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000648 261.0
TH1_k127_6822142_2 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000001576 98.0
TH1_k127_6822326_0 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 506.0
TH1_k127_6822326_1 Pilus assembly protein CpaB K02279 - - 0.0000000000000000000000000000000000002979 151.0
TH1_k127_6822326_2 AAA domain K02282 - - 0.00000000000000000000000000000003364 141.0
TH1_k127_6822326_3 PFAM TadE family protein - - - 0.000000000005078 72.0
TH1_k127_6842541_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 580.0
TH1_k127_6842541_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 445.0
TH1_k127_685075_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 367.0
TH1_k127_685075_1 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000353 204.0
TH1_k127_685075_2 Protein of unknown function (DUF3887) K06889 - - 0.0000000007375 65.0
TH1_k127_687495_0 flagellar motor switch protein FliG K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 291.0
TH1_k127_6880830_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 544.0
TH1_k127_6880830_1 PFAM polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 365.0
TH1_k127_6880830_2 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000006125 222.0
TH1_k127_6880830_3 O-methyltransferase activity K05303 - - 0.00000000000000000000000000000000000000000134 166.0
TH1_k127_6884414_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.985e-212 668.0
TH1_k127_6884414_1 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 409.0
TH1_k127_6884414_2 Fe-S cluster domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 300.0
TH1_k127_6884414_3 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000000000000009277 166.0
TH1_k127_6884414_4 - - - - 0.0000000000000000000000133 102.0
TH1_k127_6893504_0 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 289.0
TH1_k127_6893504_1 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005434 245.0
TH1_k127_6893504_2 Protein of unknown function (DUF2961) - - - 0.000000000001283 73.0
TH1_k127_6893504_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0003865 49.0
TH1_k127_6896324_0 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 399.0
TH1_k127_6896324_1 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00002707 55.0
TH1_k127_6899126_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 421.0
TH1_k127_6899126_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 283.0
TH1_k127_6899126_2 Protein of unknown function DUF47 - - - 0.00000000000000000000003736 102.0
TH1_k127_6907869_0 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001557 278.0
TH1_k127_6907869_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000008324 184.0
TH1_k127_6907869_2 NTPase - - - 0.000000000000000000000000000000000229 138.0
TH1_k127_6917391_0 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000295 224.0
TH1_k127_6917391_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000009873 216.0
TH1_k127_6917391_2 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000001637 186.0
TH1_k127_6928961_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 390.0
TH1_k127_6928961_1 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004041 283.0
TH1_k127_6928961_2 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001771 239.0
TH1_k127_6928961_3 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000003189 182.0
TH1_k127_6928961_4 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000000004301 167.0
TH1_k127_6932072_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 426.0
TH1_k127_6932072_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000002984 170.0
TH1_k127_6944416_0 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 328.0
TH1_k127_6944416_1 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.000000000000000000000000000000000000000000000000000000000005208 222.0
TH1_k127_6944416_2 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000000000000008987 195.0
TH1_k127_6965623_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 2.879e-197 624.0
TH1_k127_6965623_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000002836 237.0
TH1_k127_6965623_2 Divergent 4Fe-4S mono-cluster K05337 - - 0.00000000000000000001839 92.0
TH1_k127_7027352_0 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 1.249e-277 867.0
TH1_k127_7065587_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 492.0
TH1_k127_7065587_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000001271 204.0
TH1_k127_7085002_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 422.0
TH1_k127_7085002_1 aspartate kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001967 285.0
TH1_k127_7085002_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000007255 198.0
TH1_k127_7085002_3 ATP-binding region, ATPase domain protein domain protein - - - 0.000000000000000002641 98.0
TH1_k127_7086836_0 Proposed homoserine kinase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 563.0
TH1_k127_7086836_1 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.0000000000000000000000000002863 115.0
TH1_k127_7086938_0 Glycosyl transferase family group 2 K00752,K11936 - 2.4.1.212 9.949e-198 627.0
TH1_k127_7086938_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 309.0
TH1_k127_7103386_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 1.377e-195 621.0
TH1_k127_7103505_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 5.637e-202 638.0
TH1_k127_7103505_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 435.0
TH1_k127_7103505_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 419.0
TH1_k127_7103808_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 394.0
TH1_k127_7103808_1 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000000000000000000000000000000000000000002099 241.0
TH1_k127_7103808_2 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000003692 229.0
TH1_k127_7111073_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 594.0
TH1_k127_7111073_1 nucleic acid binding K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 323.0
TH1_k127_7111073_2 zinc ion binding K06204 - - 0.000000000000000000000000000000000000000000000003173 176.0
TH1_k127_7111073_3 Belongs to the CDS family K00981 - 2.7.7.41 0.000004585 57.0
TH1_k127_7111073_4 Universal stress protein family - - - 0.00002419 46.0
TH1_k127_7118085_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009334 271.0
TH1_k127_7123542_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 450.0
TH1_k127_7123542_1 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 344.0
TH1_k127_7123591_0 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 469.0
TH1_k127_7127779_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 311.0
TH1_k127_7127779_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000154 205.0
TH1_k127_7127779_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000001339 170.0
TH1_k127_713375_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 3.386e-216 674.0
TH1_k127_713375_1 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000001158 192.0
TH1_k127_7146076_0 Beta-lactamase enzyme family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 303.0
TH1_k127_7146076_1 Highly conserved protein containing a thioredoxin domain - - - 0.00000000000000000000001341 101.0
TH1_k127_7146076_3 PFAM TadE family protein - - - 0.0000000003842 66.0
TH1_k127_7176833_0 Protein of unknown function (DUF2961) - - - 0.0000000000000000000000000000000000006327 145.0
TH1_k127_7176833_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000001252 76.0
TH1_k127_7176833_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000005439 53.0
TH1_k127_7190849_0 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 8.238e-226 719.0
TH1_k127_7190849_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 328.0
TH1_k127_7190849_2 PFAM Silent information regulator protein Sir2 K12410 - - 0.0000000000000000000000000000000000000000000000000000000000001916 216.0
TH1_k127_7205297_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1696.0
TH1_k127_7205297_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 1.894e-243 765.0
TH1_k127_7205297_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 417.0
TH1_k127_7213502_0 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 346.0
TH1_k127_7213502_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000009805 149.0
TH1_k127_7213502_2 AIR carboxylase K06898 - - 0.0009726 42.0
TH1_k127_7217350_0 transport system involved in gliding motility auxiliary component-like K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 497.0
TH1_k127_7217350_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 335.0
TH1_k127_7217350_2 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000009253 113.0
TH1_k127_7253758_0 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 390.0
TH1_k127_7253758_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000303 164.0
TH1_k127_7260305_0 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 455.0
TH1_k127_7260305_1 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 377.0
TH1_k127_7260305_2 HEPN domain K09132 - - 0.00000000000000000001907 96.0
TH1_k127_7260305_3 Nucleotidyltransferase domain - - - 0.00000000000000002863 85.0
TH1_k127_7260305_4 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.00000000007303 63.0
TH1_k127_7282521_0 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000103 272.0
TH1_k127_7282521_1 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000002964 210.0
TH1_k127_7282521_2 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000003062 185.0
TH1_k127_7282521_3 Thioredoxin domain - - - 0.0000000000000000000000000000000002966 137.0
TH1_k127_7282521_4 TIGRFAM cytochrome d oxidase, subunit II (cydB) K00426 - 1.10.3.14 0.0000000000000000000000000000000007597 131.0
TH1_k127_7282521_5 Thioredoxin domain - - - 0.000000000000000000000000000009006 119.0
TH1_k127_7288986_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 321.0
TH1_k127_7288986_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003414 259.0
TH1_k127_7288986_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000002691 175.0
TH1_k127_7300572_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 2.618e-208 656.0
TH1_k127_7300572_1 Belongs to the Fur family K03711 - - 0.0000000000000003113 83.0
TH1_k127_7303979_0 protein-glutamate methylesterase activity K03412,K03413,K13924 - 2.1.1.80,3.1.1.61,3.5.1.44 1.052e-223 715.0
TH1_k127_7317044_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 478.0
TH1_k127_7317044_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 297.0
TH1_k127_7317044_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002385 281.0
TH1_k127_7317044_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000001443 216.0
TH1_k127_7317044_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000005995 188.0
TH1_k127_7317044_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000837 132.0
TH1_k127_7317044_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000004012 96.0
TH1_k127_7324310_0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 4.635e-242 758.0
TH1_k127_7324310_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000001574 158.0
TH1_k127_7324310_2 Domain of unknown function (DUF362) - - - 0.000000000007606 72.0
TH1_k127_7337781_0 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 609.0
TH1_k127_7342508_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 589.0
TH1_k127_7342508_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000004211 222.0
TH1_k127_7342508_2 - - - - 0.000000000000000000000000000000000000000000000000000001331 198.0
TH1_k127_7342508_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000006381 157.0
TH1_k127_7342508_4 NusB family K03625 - - 0.000000000000000000000000000000000000002258 150.0
TH1_k127_7342508_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003698 123.0
TH1_k127_7342508_6 Predicted membrane protein (DUF2232) - - - 0.000000000000000000000000000005106 131.0
TH1_k127_7342508_7 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000006425 118.0
TH1_k127_7346409_0 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 2.747e-237 737.0
TH1_k127_7346409_1 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000001817 108.0
TH1_k127_7346409_2 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.0000000000007535 68.0
TH1_k127_7358381_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 512.0
TH1_k127_7358381_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 505.0
TH1_k127_7358381_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 373.0
TH1_k127_7358381_3 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.000000000000000000000000000000000000000001083 158.0
TH1_k127_7359875_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 3.433e-261 814.0
TH1_k127_7406493_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 458.0
TH1_k127_7406493_1 NifU-like N terminal domain K04488 - - 0.0000000000000000002164 89.0
TH1_k127_7406493_2 PFAM Thioredoxin K03671 - - 0.000000000000000003286 90.0
TH1_k127_7406493_3 Phosphatidylethanolamine-binding protein K06910 - - 0.000000008745 57.0
TH1_k127_7409859_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 398.0
TH1_k127_7409859_1 Serine dehydrogenase proteinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 393.0
TH1_k127_7415270_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 569.0
TH1_k127_7415270_1 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 496.0
TH1_k127_7415270_2 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 287.0
TH1_k127_7417489_0 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 485.0
TH1_k127_7417489_1 competence protein - - - 0.000000000000000000000000001501 120.0
TH1_k127_7417489_2 Sh3 type 3 domain protein K03642,K07184 - - 0.0000000000000000000000611 108.0
TH1_k127_7422027_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein K00239,K00244 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 365.0
TH1_k127_7422027_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 290.0
TH1_k127_7422027_2 YbbR-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001556 256.0
TH1_k127_7422027_3 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
TH1_k127_7422027_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000001516 168.0
TH1_k127_7432431_0 MacB-like periplasmic core domain K02004 - - 7.722e-214 684.0
TH1_k127_7432431_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004145 276.0
TH1_k127_7432431_2 Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor K11996 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006396,GO:0006399,GO:0006400,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008641,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0016783,GO:0016874,GO:0016877,GO:0018130,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019008,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0032446,GO:0032447,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0036211,GO:0042278,GO:0042292,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0070647,GO:0071566,GO:0071704,GO:0072521,GO:0090304,GO:0090407,GO:0098822,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.80,2.8.1.11 0.000002375 54.0
TH1_k127_7441421_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 409.0
TH1_k127_7441421_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000001978 120.0
TH1_k127_7454236_0 RNB K01147,K12573 - 3.1.13.1 6.943e-225 716.0
TH1_k127_7454236_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 563.0
TH1_k127_7463013_0 TIGRFAM Phage - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 463.0
TH1_k127_7463013_1 recombinase activity - - - 0.00000000000141 72.0
TH1_k127_7486611_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.073e-226 728.0
TH1_k127_7486611_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000006898 250.0
TH1_k127_7486611_2 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000005035 127.0
TH1_k127_7486611_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000007566 117.0
TH1_k127_7486611_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000004328 85.0
TH1_k127_7486611_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000004266 77.0
TH1_k127_7498466_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001607 276.0
TH1_k127_7498466_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002895 215.0
TH1_k127_7498466_2 methyltransferase activity K00563,K02169 - 2.1.1.187,2.1.1.197 0.00000000000000000000000000000003514 135.0
TH1_k127_7501259_0 decarboxylase - - - 3.339e-202 638.0
TH1_k127_7501259_1 Domain of unknown function (DUF4198) - - - 0.000000000000000000000000000000000000000000000001769 184.0
TH1_k127_7508427_0 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004182 235.0
TH1_k127_7508427_1 PFAM Glycosyl transferase, family 39 - - - 0.00000000000000000000000000000000000000000009217 166.0
TH1_k127_7508427_2 PFAM Radical SAM domain protein - - - 0.0000000000000000000000004908 107.0
TH1_k127_7508607_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 332.0
TH1_k127_7508607_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000001455 233.0
TH1_k127_7508607_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000009338 111.0
TH1_k127_7508607_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000006282 67.0
TH1_k127_7519698_0 BT1 family - - - 2.184e-240 753.0
TH1_k127_7519698_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 393.0
TH1_k127_7519698_2 - - - - 0.0000000000000000001178 91.0
TH1_k127_7519698_3 Domain of unknown function (DUF362) - - - 0.000000000002626 75.0
TH1_k127_7519698_4 PhoD-like phosphatase - - - 0.00007283 48.0
TH1_k127_7521206_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 544.0
TH1_k127_7521206_1 - - - - 0.0000000000000001864 82.0
TH1_k127_7521206_2 - - - - 0.00000003649 63.0
TH1_k127_7561523_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1892.0
TH1_k127_7561523_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 6.029e-219 683.0
TH1_k127_7568610_0 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 329.0
TH1_k127_7568610_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 318.0
TH1_k127_7568610_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001763 253.0
TH1_k127_7568610_3 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000001685 229.0
TH1_k127_7568610_4 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000913 195.0
TH1_k127_7578196_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 6.996e-206 644.0
TH1_k127_7578196_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 441.0
TH1_k127_7578196_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 286.0
TH1_k127_7578196_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000006621 115.0
TH1_k127_7578196_4 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000001513 106.0
TH1_k127_7578196_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00003576 52.0
TH1_k127_7592918_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 347.0
TH1_k127_7592918_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 311.0
TH1_k127_7592918_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 292.0
TH1_k127_7594036_0 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 432.0
TH1_k127_7594036_1 Domain of unknown function (DUF4881) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002492 257.0
TH1_k127_7594036_2 - - - - 0.0000000000000000000000000000000000000000000005085 178.0
TH1_k127_7594036_3 membrane transporter protein K07090 - - 0.000000000000000000000007115 102.0
TH1_k127_7634711_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 381.0
TH1_k127_7634711_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000005277 194.0
TH1_k127_7639937_0 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 296.0
TH1_k127_7671815_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000007604 170.0
TH1_k127_7671815_1 PFAM UBA THIF-type NAD FAD binding - - - 0.0000000000000000000000000000000000000000896 162.0
TH1_k127_7671815_2 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000000001794 123.0
TH1_k127_7671815_3 Mut7-C ubiquitin - - - 0.00000000000000001191 85.0
TH1_k127_7706884_0 PFAM Glycosyl transferase, group 1 K12995 - 2.4.1.348 0.000000000000000000000000000000000000000000000000000000000000000000000000000003257 272.0
TH1_k127_7706884_1 PFAM Lytic K08309 - - 0.000000000000000000000000000000000000000000000000000002968 203.0
TH1_k127_7747520_0 Elongation factor Tu domain 2 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 428.0
TH1_k127_7747520_1 PFAM TrkA-N domain protein K03499 - - 0.00000000009036 62.0
TH1_k127_7748514_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 571.0
TH1_k127_7750347_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 381.0
TH1_k127_7750347_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000196 144.0
TH1_k127_7803367_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 566.0
TH1_k127_7816304_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.23e-270 843.0
TH1_k127_7816304_1 Sodium calcium exchanger membrane K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 578.0
TH1_k127_7816304_2 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 358.0
TH1_k127_7816304_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008106 250.0
TH1_k127_7816304_4 Ion transport 2 domain protein - - - 0.000000000000000000004472 96.0
TH1_k127_7816304_5 Auxin binding protein - - - 0.0000000000000000009233 89.0
TH1_k127_7819798_0 protein-glutamate methylesterase activity K03412,K03413,K13924 - 2.1.1.80,3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 498.0
TH1_k127_7819798_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000002858 131.0
TH1_k127_783512_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 565.0
TH1_k127_783512_1 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
TH1_k127_7835448_0 PFAM Anthranilate synthase component I K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 456.0
TH1_k127_7835448_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 297.0
TH1_k127_7835448_2 lyase activity - - - 0.0000000000000000000000000006677 115.0
TH1_k127_7838563_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001122 264.0
TH1_k127_7838563_1 phosphorelay sensor kinase activity K07708,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000005705 252.0
TH1_k127_7838563_2 - - - - 0.00000000000004163 81.0
TH1_k127_7841020_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1026.0
TH1_k127_7841020_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000055 288.0
TH1_k127_7841020_2 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000105 231.0
TH1_k127_7841020_3 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000004735 197.0
TH1_k127_7841020_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000002567 145.0
TH1_k127_7855244_0 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 497.0
TH1_k127_7855244_1 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002814 258.0
TH1_k127_7855244_2 signal transduction HD GYP protein - - - 0.0000000000000000000008608 106.0
TH1_k127_7864343_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 569.0
TH1_k127_7864343_1 TIGRFAM hydro-lyases, Fe-S type, tartrate fumarate subfamily, alpha region K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 415.0
TH1_k127_7864343_2 TIGRFAM hydro-lyases, Fe-S type, tartrate fumarate subfamily, beta region K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003822 267.0
TH1_k127_7864343_3 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 268.0
TH1_k127_7864343_4 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000003576 163.0
TH1_k127_788622_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 396.0
TH1_k127_788622_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 387.0
TH1_k127_7900543_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000005512 235.0
TH1_k127_7900543_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000006628 197.0
TH1_k127_7900543_2 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000004421 185.0
TH1_k127_7900543_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000009512 152.0
TH1_k127_7900543_4 Cobalt transport protein K02008 - - 0.00000000000000000000000000000348 129.0
TH1_k127_7900543_5 PFAM Rhodanese domain protein - - - 0.000000000000000000000000963 106.0
TH1_k127_7900543_6 Large extracellular alpha-helical protein K16915 - - 0.000002243 56.0
TH1_k127_7900543_7 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000005792 49.0
TH1_k127_7907490_0 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 430.0
TH1_k127_7907490_1 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000001058 206.0
TH1_k127_7910812_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0 1152.0
TH1_k127_7910812_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 300.0
TH1_k127_7910812_2 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000009976 114.0
TH1_k127_7940054_0 transferase activity, transferring glycosyl groups K19424 - - 0.000000000006971 75.0
TH1_k127_7949255_0 Belongs to the ClpX chaperone family - - - 7.827e-226 709.0
TH1_k127_7949255_1 PFAM Radical SAM K22226 - - 4.333e-197 620.0
TH1_k127_7973968_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 4.948e-305 946.0
TH1_k127_7973968_1 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 0.0000000000000000000000000000000000000000000000000000000000000000004322 234.0
TH1_k127_7987972_0 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000004372 224.0
TH1_k127_7987972_1 heat shock protein binding - - - 0.00000000000000000000000004401 112.0
TH1_k127_7987972_2 - - - - 0.000000000000000000007572 99.0
TH1_k127_7990641_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000004159 261.0
TH1_k127_7990641_1 FecR protein - - - 0.00000000000000000000000000000000000002416 153.0
TH1_k127_7990641_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000001039 59.0
TH1_k127_8041381_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 432.0
TH1_k127_8041381_1 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002725 285.0
TH1_k127_8041381_2 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001452 265.0
TH1_k127_8041381_3 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000262 261.0
TH1_k127_8041381_4 PFAM Phosphoribosyltransferase - - - 0.00000000005621 65.0
TH1_k127_8042777_0 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 449.0
TH1_k127_8042777_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003942 272.0
TH1_k127_8042777_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003308 261.0
TH1_k127_8042777_3 Signal transduction histidine kinase - - - 0.0000000000000000000000008507 122.0
TH1_k127_8042777_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000007848 70.0
TH1_k127_8058262_0 Protein of unknown function (DUF933) K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 461.0
TH1_k127_8058262_1 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 451.0
TH1_k127_8058262_2 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000000000000000004692 199.0
TH1_k127_8124437_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000001125 181.0
TH1_k127_8124437_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000006333 160.0
TH1_k127_8156440_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004135 246.0
TH1_k127_8156440_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000004012 100.0
TH1_k127_8157255_0 PFAM magnesium chelatase K07391 - - 5.544e-227 712.0
TH1_k127_8157255_1 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001167 266.0
TH1_k127_8157255_2 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000005283 162.0
TH1_k127_8157255_3 - - - - 0.0000000000000000000000004238 108.0
TH1_k127_8168397_0 Transposase DDE domain - - - 2.445e-257 801.0
TH1_k127_8179397_0 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007919 269.0
TH1_k127_8179397_1 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.000000000000000000000000000000000000000003891 156.0
TH1_k127_8179397_2 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000386 130.0
TH1_k127_8179397_3 histidine kinase HAMP region domain protein K03406 - - 0.0000351 54.0
TH1_k127_8213472_0 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 354.0
TH1_k127_8213472_1 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 297.0
TH1_k127_8235150_0 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 488.0
TH1_k127_8235150_1 Protein of unknown function DUF134 - - - 0.00000000000000000000000000000000000000004003 156.0
TH1_k127_8235150_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000003384 120.0
TH1_k127_8306152_0 cell septum assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000006143 247.0
TH1_k127_8306152_1 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000001233 216.0
TH1_k127_8306152_2 - - - - 0.00000000000000000000000000001014 119.0
TH1_k127_8306152_3 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000008906 91.0
TH1_k127_8309932_0 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000000000000000001277 176.0
TH1_k127_8309932_2 - - - - 0.0000000003459 68.0
TH1_k127_8328379_0 Endoribonuclease that initiates mRNA decay K18682 - - 5.523e-199 625.0
TH1_k127_8328379_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 552.0
TH1_k127_8328379_2 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 379.0
TH1_k127_8330468_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 500.0
TH1_k127_8330468_1 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 413.0
TH1_k127_8330468_2 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 400.0
TH1_k127_8330468_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 388.0
TH1_k127_8330468_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 359.0
TH1_k127_8330468_5 PBP superfamily domain K02040 - - 0.00000004045 55.0
TH1_k127_8331995_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000722 220.0
TH1_k127_8331995_1 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000001611 212.0
TH1_k127_8331995_2 Domain of unknown function (DUF4412) - - - 0.00000000000000000000000000000002045 134.0
TH1_k127_8355307_0 Glutathionylspermidine synthase preATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 306.0
TH1_k127_8355307_1 Domain of Unknown Function (DUF350) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001519 239.0
TH1_k127_8385958_0 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000007003 194.0
TH1_k127_8385958_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000764 156.0
TH1_k127_8385958_2 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000000000001347 131.0
TH1_k127_8385958_3 Bacterial PH domain - - - 0.00000000000000001413 88.0
TH1_k127_8385958_4 overlaps another CDS with the same product name - - - 0.000000000001657 79.0
TH1_k127_8400378_0 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 406.0
TH1_k127_8400378_1 filamentation induced by cAMP protein Fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000001594 238.0
TH1_k127_8417776_0 ATP-dependent nuclease subunit B-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 486.0
TH1_k127_8417776_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000005289 171.0
TH1_k127_8421000_0 Catalyzes the insertion of Co(2 ) into sirohydrochlorin K02190 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0016829,GO:0016852,GO:0020037,GO:0022607,GO:0042597,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050897,GO:0051259,GO:0051262,GO:0051266,GO:0065003,GO:0071840,GO:0097159,GO:1901363 4.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 315.0
TH1_k127_8421000_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 304.0
TH1_k127_8427957_0 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 3.469e-227 719.0
TH1_k127_8427957_1 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 521.0
TH1_k127_8435161_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.994e-208 662.0
TH1_k127_8435161_1 Cache_2 - - - 0.00000000000000000001041 95.0
TH1_k127_8460100_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009622 383.0
TH1_k127_8460100_1 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000005587 249.0
TH1_k127_8460100_2 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000008872 234.0
TH1_k127_8478458_0 Tetratricopeptide repeats - - - 5.123e-321 1020.0
TH1_k127_8478458_1 Radical SAM superfamily K22226 - - 0.0000002204 58.0
TH1_k127_8490576_0 Domain of unknown function (DUF4301) - - - 0.00000000000000000000000000000000000000000000000000000000000008472 215.0
TH1_k127_8490576_1 transcriptional regulator, AsnC family - - - 0.000000000000000000000000000000000000005589 149.0
TH1_k127_8490576_2 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000003739 116.0
TH1_k127_8501387_0 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 342.0
TH1_k127_8501387_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000008352 173.0
TH1_k127_8518050_0 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 553.0
TH1_k127_8518050_1 PFAM Carbohydrate purine kinase K00847 - 2.7.1.4 0.0001028 47.0
TH1_k127_852320_0 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 391.0
TH1_k127_852320_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 351.0
TH1_k127_852320_2 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 293.0
TH1_k127_852320_3 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000002007 169.0
TH1_k127_85479_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.159e-267 838.0
TH1_k127_85479_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000867 70.0
TH1_k127_8549482_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 560.0
TH1_k127_8549482_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 537.0
TH1_k127_8549482_2 Protein of unknown function (DUF2905) - - - 0.00000000000000000000006714 99.0
TH1_k127_8556977_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 7.46e-209 659.0
TH1_k127_8560319_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 327.0
TH1_k127_8560319_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 321.0
TH1_k127_8560319_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001079 269.0
TH1_k127_8560319_3 - - - - 0.000000000000000000000000000000000000000000006457 166.0
TH1_k127_8560319_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000003039 105.0
TH1_k127_8599091_0 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000009786 210.0
TH1_k127_8599091_1 MOSC domain - - - 0.00000000000000000000000000000000000000000000000001028 184.0
TH1_k127_8599091_2 Protein of unknown function (DUF2652) - - - 0.0000000000000000000000000000000000001413 150.0
TH1_k127_8599091_3 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000003229 125.0
TH1_k127_8637254_0 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 594.0
TH1_k127_8637254_1 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 339.0
TH1_k127_8637254_2 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002614 240.0
TH1_k127_8674209_0 Transcriptional regulator, MerR family - - - 0.000000000000000000000000000000000000000000000000000000000000001698 220.0
TH1_k127_8674209_1 - - - - 0.000000000000000000000000000000000000000000000000000000000005743 214.0
TH1_k127_8674209_2 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000002718 196.0
TH1_k127_8674209_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000005064 183.0
TH1_k127_8674209_4 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.00000000000000000000000000000005666 125.0
TH1_k127_8674209_5 granule-associated protein - - - 0.00000000000000000000005913 104.0
TH1_k127_8674209_6 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00009516 52.0
TH1_k127_8678426_0 GXGXG motif - - - 0.0 1156.0
TH1_k127_8683982_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000737 480.0
TH1_k127_8683982_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000005739 123.0
TH1_k127_8683982_2 - - - - 0.0000002055 58.0
TH1_k127_8693407_0 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 317.0
TH1_k127_8693407_2 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000007844 186.0
TH1_k127_8693407_3 Thioesterase - - - 0.0000000000000000000000000000000000000000000488 164.0
TH1_k127_8693407_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000001196 81.0
TH1_k127_8735884_0 PFAM periplasmic solute binding protein K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 319.0
TH1_k127_8735884_1 PFAM ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003356 276.0
TH1_k127_8758930_0 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 2.451e-199 625.0
TH1_k127_8758930_1 Pterin binding enzyme K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 488.0
TH1_k127_8758930_2 radical SAM domain protein K03716 - 4.1.99.14 0.0000000000000000000000000000000000000000000000000000000000000000000000001924 253.0
TH1_k127_8761339_0 Conserved region in glutamate synthase - - - 2.263e-281 872.0
TH1_k127_8761339_1 4Fe-4S dicluster domain - - - 0.0001548 46.0
TH1_k127_8778919_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 384.0
TH1_k127_8778919_1 PFAM glycosyl transferase, family 9 K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001985 287.0
TH1_k127_8778919_2 Pfam:Pyridox_oxidase - - - 0.000000000000000004171 94.0
TH1_k127_8778919_3 Glycosyl transferase family 2 - - - 0.00000000009301 63.0
TH1_k127_8786406_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 458.0
TH1_k127_8786406_1 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 364.0
TH1_k127_8831414_0 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000001806 207.0
TH1_k127_8831414_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000001375 161.0
TH1_k127_8831414_2 COG2206 HD-GYP domain - - - 0.00000000000000000000000000136 125.0
TH1_k127_8848150_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 7.605e-248 770.0
TH1_k127_886593_0 - - - - 0.000000000000000000000000000000000005328 139.0
TH1_k127_886593_1 L,D-transpeptidase catalytic domain - - - 0.0000000001715 69.0
TH1_k127_886593_2 PFAM Band 7 protein - - - 0.0000002859 51.0
TH1_k127_886593_3 - - - - 0.00001324 50.0
TH1_k127_8867314_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 382.0
TH1_k127_8867314_1 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000001377 130.0
TH1_k127_8867314_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 0.0000000000005159 70.0
TH1_k127_8880796_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 1.165e-196 618.0
TH1_k127_8880796_1 Ion transport 2 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 342.0
TH1_k127_8880796_2 Sodium calcium exchanger membrane K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001033 274.0
TH1_k127_8895079_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 1.923e-231 721.0
TH1_k127_8895079_1 - - - - 0.00000000000000000000000000000000000004037 145.0
TH1_k127_8895079_2 Serine dehydrogenase proteinase - - - 0.0000002753 52.0
TH1_k127_8909972_0 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 406.0
TH1_k127_8909972_1 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000005041 133.0
TH1_k127_8910639_0 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 480.0
TH1_k127_8910639_1 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 445.0
TH1_k127_8910639_2 Methionyl-tRNA formyltransferase K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002214 249.0
TH1_k127_8910639_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000005774 187.0
TH1_k127_8910639_4 - - - - 0.00000000009761 68.0
TH1_k127_8928311_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 363.0
TH1_k127_8928311_1 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000001267 245.0
TH1_k127_8928311_2 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000007673 128.0
TH1_k127_8938446_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 379.0
TH1_k127_8938446_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 311.0
TH1_k127_8952156_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 473.0
TH1_k127_8952156_1 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 314.0
TH1_k127_8956450_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 368.0
TH1_k127_8956450_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000001086 246.0
TH1_k127_8956450_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001407 250.0
TH1_k127_8956450_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000006369 97.0
TH1_k127_8959705_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 415.0
TH1_k127_8959705_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000008061 76.0
TH1_k127_8974229_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.18e-217 681.0
TH1_k127_8974229_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 314.0
TH1_k127_8974229_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000001016 241.0
TH1_k127_8974229_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000008277 187.0
TH1_k127_8977198_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 9.46e-214 674.0
TH1_k127_8987123_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 435.0
TH1_k127_8987123_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001666 284.0
TH1_k127_8987123_2 AMP binding - - - 0.00007383 51.0
TH1_k127_899137_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 430.0
TH1_k127_899137_1 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000003708 201.0
TH1_k127_899137_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis - - - 0.0000000000000000000000000003797 117.0
TH1_k127_9022697_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 479.0
TH1_k127_9022697_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002764 239.0
TH1_k127_9022697_2 spore germination K16928 - - 0.0000000000000000000000000000000000000000000000000000000000000000005575 236.0
TH1_k127_9022697_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000009347 213.0
TH1_k127_9035571_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 427.0
TH1_k127_9035571_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002096 259.0
TH1_k127_9035571_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000504 221.0
TH1_k127_9050862_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.0 1021.0
TH1_k127_9050862_1 Efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 526.0
TH1_k127_9050862_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000341 240.0
TH1_k127_9073033_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 332.0
TH1_k127_9073033_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001385 230.0
TH1_k127_9073033_2 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002864 213.0
TH1_k127_9073033_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000002509 206.0
TH1_k127_9073033_4 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000006934 161.0
TH1_k127_9073033_5 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000004382 130.0
TH1_k127_9073033_6 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000001471 122.0
TH1_k127_9073033_7 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000002145 76.0
TH1_k127_9082957_0 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000003484 234.0
TH1_k127_9082957_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000002829 229.0
TH1_k127_9082957_2 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000007366 230.0
TH1_k127_9082957_3 - - - - 0.000000000000000000000000000000000005561 140.0
TH1_k127_9082957_4 - - - - 0.000000000000000000000000000004136 123.0
TH1_k127_9082957_5 Pirin K06911 - - 0.00000000000000000004369 92.0
TH1_k127_9082957_6 - - - - 0.00000001489 64.0
TH1_k127_9104196_0 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 418.0
TH1_k127_9104196_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 296.0
TH1_k127_9104196_2 Cold shock K03704 - - 0.0000000000000000000000003319 109.0
TH1_k127_9104196_3 Transcriptional Coactivator p15 (PC4) - GO:0003674,GO:0003712,GO:0003713,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005667,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0044087,GO:0044089,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0045944,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0060260,GO:0060261,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.00000272 54.0
TH1_k127_9137275_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009582 383.0
TH1_k127_9137275_1 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 304.0
TH1_k127_9149244_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 569.0
TH1_k127_9149244_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 338.0
TH1_k127_9149244_2 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000789 55.0
TH1_k127_9156017_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 486.0
TH1_k127_9164850_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 8.023e-195 623.0
TH1_k127_9164850_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000005241 204.0
TH1_k127_9164850_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000001165 143.0
TH1_k127_9164850_3 PFAM CBS domain containing protein - - - 0.0000000000000000000000000002129 119.0
TH1_k127_9164850_4 Protein conserved in bacteria - - - 0.000000000000000000004251 101.0
TH1_k127_9177144_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.184e-194 614.0
TH1_k127_9177144_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 366.0
TH1_k127_9177144_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 320.0
TH1_k127_9177144_3 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000002652 124.0
TH1_k127_9177144_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000002927 119.0
TH1_k127_9255648_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 336.0
TH1_k127_9255917_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 552.0
TH1_k127_9255917_1 RNB K12573 - - 0.00000000000000000000000000164 118.0
TH1_k127_9270170_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 504.0
TH1_k127_9270170_1 sugar transferase - - - 0.00000000000000000000000000002342 119.0
TH1_k127_9315263_0 PFAM Glycosyl hydrolases family 8 K20542 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 359.0
TH1_k127_9315263_1 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.000000000000000000000000000000000000000000000000000000000000000006953 241.0
TH1_k127_9321451_0 CoA binding domain K09181 - - 4.883e-245 769.0
TH1_k127_934662_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1039.0
TH1_k127_9351332_0 BadF BadG BcrA BcrD - - - 1.39e-228 717.0
TH1_k127_9351332_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 489.0
TH1_k127_9351332_2 integral membrane protein - - - 0.00000000000000000000000000000000000000000006333 169.0
TH1_k127_9382462_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 399.0
TH1_k127_9382462_1 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000003087 125.0
TH1_k127_9409887_0 Glycosyltransferase like family 2 K03606,K07011 - - 0.000000000000000000000000000000000000009071 158.0
TH1_k127_9409887_1 Oligosaccharide biosynthesis protein Alg14 like - - - 0.000000000000000000000006352 106.0
TH1_k127_9409887_3 sugar transferase - - - 0.0000000000000311 78.0
TH1_k127_9409887_4 Glycosyltransferase family 28 C-terminal domain - - - 0.00000003742 61.0
TH1_k127_9425950_0 PFAM Peptidase M20 K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 515.0
TH1_k127_9425950_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795 394.0
TH1_k127_9425950_2 domain protein K01992,K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 326.0
TH1_k127_9425950_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 295.0
TH1_k127_9425950_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000002809 195.0
TH1_k127_9425950_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000666 193.0
TH1_k127_9427242_0 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 371.0
TH1_k127_9427242_1 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001401 247.0
TH1_k127_9427242_2 TIGRFAM hydrogenase maturation protease K00442 - - 0.00000000000000000000000001365 111.0
TH1_k127_9444077_0 Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 502.0
TH1_k127_9444077_1 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.00000000000009223 78.0
TH1_k127_9444077_2 AAA domain K01935 - 6.3.3.3 0.0000000588 56.0
TH1_k127_9452529_0 ABC-type multidrug transport system ATPase and permease K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 536.0
TH1_k127_9453746_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 353.0
TH1_k127_9453746_1 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003597 277.0
TH1_k127_9453746_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000001836 79.0
TH1_k127_9455138_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 4.515e-196 622.0
TH1_k127_9455138_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 503.0
TH1_k127_9455138_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000008519 252.0
TH1_k127_9455138_3 Gram-negative-bacterium-type cell wall biogenesis - - - 0.00000000000000000000000000000000000002296 156.0
TH1_k127_9455138_4 PFAM phosphotransferase KptA Tpt1 K07559 - - 0.00000000000000000000000000000000000302 145.0
TH1_k127_9455138_5 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000005056 130.0
TH1_k127_9455138_6 response regulator - - - 0.000000000000000000001618 98.0
TH1_k127_9455138_7 YHS domain - - - 0.0000000000000000001179 91.0
TH1_k127_9464998_0 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 492.0
TH1_k127_9464998_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 463.0
TH1_k127_9464998_2 PFAM HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000000005591 238.0
TH1_k127_9464998_3 PFAM Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000004253 221.0
TH1_k127_9464998_4 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000005785 194.0
TH1_k127_9469001_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 467.0
TH1_k127_9469001_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 297.0
TH1_k127_9469001_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000002224 192.0
TH1_k127_9469001_3 - - - - 0.000000000000000000000000000000002512 135.0
TH1_k127_9469001_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000007743 72.0
TH1_k127_9508159_0 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 499.0
TH1_k127_9508159_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000001665 171.0
TH1_k127_9508159_2 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000001047 124.0
TH1_k127_9510819_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.376e-301 937.0
TH1_k127_9514807_0 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 3.059e-195 612.0
TH1_k127_9514807_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 1.197e-194 620.0
TH1_k127_9514807_2 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000001569 172.0
TH1_k127_9514807_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000227 106.0
TH1_k127_9514807_5 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.0000000214 55.0
TH1_k127_9514901_0 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 346.0
TH1_k127_9514901_1 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007796 270.0
TH1_k127_9514901_2 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000001538 179.0
TH1_k127_9519628_0 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 540.0
TH1_k127_9519628_1 PFAM Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 290.0
TH1_k127_9519628_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000003623 178.0
TH1_k127_9575944_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 600.0
TH1_k127_9575944_1 - - - - 0.00000000000000000000000000000000000000000000000000000111 201.0
TH1_k127_9575944_2 Methyltransferase domain K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000001648 172.0
TH1_k127_9588900_0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000003904 182.0
TH1_k127_9588900_1 PHP domain protein K02347 - - 0.00000000000000000000000000000000001481 137.0
TH1_k127_9588900_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000003593 87.0
TH1_k127_97754_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 306.0
TH1_k127_97754_1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' - - - 0.000000000000000000000000003698 121.0
TH1_k127_985919_0 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 3.943e-202 636.0
TH1_k127_985919_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 366.0
TH1_k127_985919_2 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 367.0
TH1_k127_985919_3 Mammalian cell entry related domain protein K02067,K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003337 274.0
TH1_k127_985919_4 Protein of unknown function (DUF434) - - - 0.00000000000000000000000000000000000000000000000000000000000002352 220.0
TH1_k127_985919_5 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000000000000000005049 183.0
TH1_k127_985919_6 - - - - 0.0000000000000000000000001301 113.0
TH1_k127_985919_7 - - - - 0.000000000000000000002287 101.0
TH1_k127_985919_8 - - - - 0.000000000000000007766 90.0
TH1_k127_985919_9 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000166 77.0
TH1_k127_99514_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 473.0
TH1_k127_99514_1 membrane-bound metal-dependent K07038 - - 0.0000001217 57.0
TH1_k127_999911_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 519.0
TH1_k127_999911_1 4-alpha-glucanotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 470.0
TH1_k127_999911_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 408.0
TH1_k127_999911_4 THUMP - - - 0.00000000000000000000000000006681 118.0