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Overview

ID MAG03849
Name TH1_bin.18
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA9159
Genus
Species
Assembly information
Completeness (%) 73.11
Contamination (%) 0.16
GC content (%) 56.0
N50 (bp) 5,534
Genome size (bp) 1,816,459

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1872

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_1035584_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.902e-240 758.0
TH1_k127_1035584_1 LysM domain K01449,K19223 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000005713 245.0
TH1_k127_1035584_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000001119 179.0
TH1_k127_1035584_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000002905 130.0
TH1_k127_1035584_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000006386 125.0
TH1_k127_1035584_5 Histidine kinase - - - 0.00007245 54.0
TH1_k127_1035584_6 - - - - 0.0001034 49.0
TH1_k127_1038529_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 561.0
TH1_k127_1038529_1 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 433.0
TH1_k127_1038529_2 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 364.0
TH1_k127_1038529_3 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 344.0
TH1_k127_1038529_4 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 334.0
TH1_k127_1038529_5 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.000000000000000000000000000000000000000000000000000000000001083 217.0
TH1_k127_1038529_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000002089 76.0
TH1_k127_10452_0 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008891 245.0
TH1_k127_10452_1 - - - - 0.0000000000000000000000000000000000000000001272 174.0
TH1_k127_10452_2 Glycosyltransferase Family 4 - - - 0.0003059 46.0
TH1_k127_1076746_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 407.0
TH1_k127_1076746_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 348.0
TH1_k127_1076746_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009369 241.0
TH1_k127_1076746_3 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.0000000000000000005476 95.0
TH1_k127_1076804_0 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 2.879e-207 651.0
TH1_k127_1076804_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 606.0
TH1_k127_1076804_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000001058 204.0
TH1_k127_1076804_3 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000004602 106.0
TH1_k127_1076804_4 response regulator - - - 0.00000000000003297 83.0
TH1_k127_1111119_0 Nitroreductase - - - 4.46e-204 651.0
TH1_k127_1111119_1 L,D-transpeptidase catalytic domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 411.0
TH1_k127_1111119_2 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 319.0
TH1_k127_1123656_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 525.0
TH1_k127_1123656_1 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 393.0
TH1_k127_1123656_2 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 302.0
TH1_k127_1123656_3 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006016 287.0
TH1_k127_1123656_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000001364 228.0
TH1_k127_1123656_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000001684 231.0
TH1_k127_1123656_6 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000007928 117.0
TH1_k127_1123656_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000551 102.0
TH1_k127_1148119_0 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000007166 226.0
TH1_k127_1148119_1 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000002273 147.0
TH1_k127_1160655_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 604.0
TH1_k127_1160655_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 383.0
TH1_k127_1160655_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000001328 203.0
TH1_k127_1160655_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000007405 194.0
TH1_k127_1160655_4 - - - - 0.00000000000000000000000000000000000000000000001435 175.0
TH1_k127_1160655_5 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000000255 122.0
TH1_k127_1160655_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0001851 48.0
TH1_k127_1232327_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.595e-219 685.0
TH1_k127_1232327_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 441.0
TH1_k127_1232327_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000001812 258.0
TH1_k127_1232327_3 cheY-homologous receiver domain - - - 0.0000006275 54.0
TH1_k127_1243321_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001969 273.0
TH1_k127_127499_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 443.0
TH1_k127_127499_1 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 340.0
TH1_k127_127499_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000187 282.0
TH1_k127_127499_3 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000001152 111.0
TH1_k127_127499_4 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000009731 102.0
TH1_k127_1279040_0 Peptidase family M48 - - - 0.00000000157 69.0
TH1_k127_1279040_1 Anion-transporting ATPase K01551 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.6.3.16 0.00000005923 55.0
TH1_k127_1350826_0 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000001117 212.0
TH1_k127_1350826_1 auxin-activated signaling pathway K07088 - - 0.0000000000000000000000000000000000000000000000000000007968 203.0
TH1_k127_1350826_2 DGC domain - - - 0.000000000000000000000000000000000000000000000000000007826 194.0
TH1_k127_1350826_3 HD domain - - - 0.000000000000000000000000000000000000000000000000001332 199.0
TH1_k127_1350826_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000003081 168.0
TH1_k127_1350826_5 Protein of unknown function (DUF3300) - - - 0.000000000000000002806 87.0
TH1_k127_1350826_6 Short C-terminal domain - - - 0.00000006016 57.0
TH1_k127_1364447_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 359.0
TH1_k127_1364447_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000002889 241.0
TH1_k127_1397192_0 NACHT nucleoside triphosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001106 274.0
TH1_k127_1397192_1 Nacht domain K06147 - - 0.000000000000000000000000000002584 123.0
TH1_k127_1459716_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000006541 233.0
TH1_k127_1459716_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000003865 225.0
TH1_k127_1459716_2 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000000000002113 141.0
TH1_k127_1459716_3 - - - - 0.00000006154 56.0
TH1_k127_1461156_0 hexose biosynthetic process K01810 - 5.3.1.9 4.18e-270 837.0
TH1_k127_1461156_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000002643 188.0
TH1_k127_1463489_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1210.0
TH1_k127_1463489_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.501e-276 866.0
TH1_k127_1463489_2 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 375.0
TH1_k127_1463489_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000004193 244.0
TH1_k127_1463489_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001909 130.0
TH1_k127_1483228_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 517.0
TH1_k127_1483228_1 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000000000004727 234.0
TH1_k127_1483228_2 COG1450 Type II secretory pathway, component PulD K02453 - - 0.000000000000000000000000000000000000000000000000007496 202.0
TH1_k127_1483228_3 YbbR-like protein - - - 0.000000002674 60.0
TH1_k127_1486400_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.558e-296 928.0
TH1_k127_1486400_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 593.0
TH1_k127_1486400_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 324.0
TH1_k127_1486400_3 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000009126 253.0
TH1_k127_1486400_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000005102 246.0
TH1_k127_1486400_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000001372 138.0
TH1_k127_1486400_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000005968 85.0
TH1_k127_1486400_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000001942 56.0
TH1_k127_1486400_8 Protein of unknown function (DUF721) - - - 0.0000004031 58.0
TH1_k127_150500_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 500.0
TH1_k127_150500_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 338.0
TH1_k127_150500_2 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000002382 251.0
TH1_k127_1514459_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 609.0
TH1_k127_1514459_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 482.0
TH1_k127_1514459_10 - - - - 0.00000000000000000000005244 99.0
TH1_k127_1514459_11 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000003204 97.0
TH1_k127_1514459_12 - - - - 0.000000000000000006878 85.0
TH1_k127_1514459_2 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 333.0
TH1_k127_1514459_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 327.0
TH1_k127_1514459_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001333 268.0
TH1_k127_1514459_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002298 269.0
TH1_k127_1514459_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000105 200.0
TH1_k127_1514459_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000005125 154.0
TH1_k127_1514459_8 Uncharacterized ACR, COG1678 - - - 0.00000000000000000000000000000000000009018 153.0
TH1_k127_1514459_9 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000001378 117.0
TH1_k127_1534667_0 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 589.0
TH1_k127_1534667_1 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 571.0
TH1_k127_1534667_2 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 519.0
TH1_k127_1534667_3 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 335.0
TH1_k127_1535759_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 536.0
TH1_k127_1535759_1 PFAM Polysaccharide export protein K01991 - - 0.00000000000000000000000000000003192 133.0
TH1_k127_1535759_2 peptidyl-tyrosine sulfation - - - 0.0000000000000001507 89.0
TH1_k127_1537991_0 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 363.0
TH1_k127_1537991_1 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000002477 147.0
TH1_k127_1537991_2 TPR repeat - - - 0.00000000003757 75.0
TH1_k127_1537991_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0001292 55.0
TH1_k127_1561237_0 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004464 251.0
TH1_k127_1561237_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000002017 239.0
TH1_k127_1566882_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 4.623e-265 828.0
TH1_k127_1566882_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000003418 104.0
TH1_k127_1599560_0 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004958 279.0
TH1_k127_1599560_1 Putative beta-barrel porin 2 K20920 - - 0.000000000000000000000000000000000000000000000004617 187.0
TH1_k127_1599560_2 G-rich domain on putative tyrosine kinase K16554 - - 0.00000000000000000000000000000000005463 143.0
TH1_k127_1637593_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 340.0
TH1_k127_1637593_1 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000193 179.0
TH1_k127_1637593_2 DNA restriction-modification system - - - 0.000000003511 60.0
TH1_k127_1650784_0 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000155 278.0
TH1_k127_1650784_1 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000000009275 103.0
TH1_k127_1650784_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000004197 100.0
TH1_k127_1690411_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 490.0
TH1_k127_1690411_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 300.0
TH1_k127_1690411_2 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000009004 183.0
TH1_k127_1690411_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000001114 142.0
TH1_k127_1690411_4 deoxyhypusine monooxygenase activity K05386 - - 0.0000000000000000003485 93.0
TH1_k127_169654_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 439.0
TH1_k127_169654_1 - K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 421.0
TH1_k127_169654_2 Belongs to the heme-copper respiratory oxidase family K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 417.0
TH1_k127_169654_3 Cytochrome b5-like Heme/Steroid binding domain K07245,K14166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006542 286.0
TH1_k127_169654_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000152 151.0
TH1_k127_169654_5 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000005013 156.0
TH1_k127_169654_6 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000001054 141.0
TH1_k127_169654_7 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000004482 76.0
TH1_k127_169654_8 cyclic diguanylate phosphodiesterase - - - 0.00000000001435 66.0
TH1_k127_169654_9 Universal stress protein family - - - 0.000000004256 66.0
TH1_k127_1705286_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 503.0
TH1_k127_1705286_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000009588 259.0
TH1_k127_1705286_2 prephenate dehydrogenase (NADP+) activity K00210,K00211,K00220,K02013,K04517,K14187 GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,1.3.1.13,1.3.1.43,3.6.3.34,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000006002 242.0
TH1_k127_1705286_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000009827 213.0
TH1_k127_1705455_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 5.631e-232 734.0
TH1_k127_1705455_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 617.0
TH1_k127_1705455_2 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 466.0
TH1_k127_1705455_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0000000000000000000000000000000000000000000000000000000000004754 213.0
TH1_k127_1705455_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000002636 156.0
TH1_k127_1705455_5 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000007664 148.0
TH1_k127_1705455_6 membrane - - - 0.000000000000000000000001518 105.0
TH1_k127_1705455_7 Response regulator receiver - - - 0.00000000000000000000000186 106.0
TH1_k127_1717178_0 Histidine kinase - - - 1.069e-203 671.0
TH1_k127_1717178_1 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002669 282.0
TH1_k127_1717178_2 PHP-associated K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000001785 210.0
TH1_k127_1717178_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000002784 184.0
TH1_k127_1717178_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000005289 143.0
TH1_k127_1717178_5 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000009296 119.0
TH1_k127_1717178_6 DRTGG domain - - - 0.000000000000000000000000002862 117.0
TH1_k127_1717178_7 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.0000000000000003431 79.0
TH1_k127_1763000_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005177 285.0
TH1_k127_1763000_1 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000104 272.0
TH1_k127_1763000_2 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000007431 194.0
TH1_k127_1763000_3 Signal peptidase K13280 - 3.4.21.89 0.00000004671 61.0
TH1_k127_1782427_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.42e-280 877.0
TH1_k127_1782427_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 524.0
TH1_k127_1836353_0 Chain length determinant protein K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 387.0
TH1_k127_1836353_1 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.00000000000000006393 87.0
TH1_k127_188973_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1073.0
TH1_k127_188973_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 4.411e-220 691.0
TH1_k127_188973_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 437.0
TH1_k127_188973_3 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 421.0
TH1_k127_188973_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 432.0
TH1_k127_188973_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 332.0
TH1_k127_188973_6 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000007623 241.0
TH1_k127_188973_7 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000007164 142.0
TH1_k127_188973_8 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0000000000000000000000003363 104.0
TH1_k127_1892456_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 3.117e-295 919.0
TH1_k127_1892456_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 372.0
TH1_k127_1892456_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 317.0
TH1_k127_1892456_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 310.0
TH1_k127_1892456_4 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000004177 236.0
TH1_k127_1892456_5 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000001812 226.0
TH1_k127_1892456_6 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000539 177.0
TH1_k127_1892456_7 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000000000000000000000002887 186.0
TH1_k127_1892456_8 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000001007 169.0
TH1_k127_1892456_9 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000005829 124.0
TH1_k127_1933403_0 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 543.0
TH1_k127_1933403_1 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001541 265.0
TH1_k127_1933403_3 phosphorelay signal transduction system K07315 - 3.1.3.3 0.0000002124 53.0
TH1_k127_199399_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 352.0
TH1_k127_199399_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000002677 241.0
TH1_k127_199399_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000002132 194.0
TH1_k127_199399_3 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000008376 168.0
TH1_k127_199399_4 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000007824 168.0
TH1_k127_199399_5 AP endonuclease family 2 K01151 - 3.1.21.2 0.0002845 44.0
TH1_k127_1998819_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 432.0
TH1_k127_1998819_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000001768 161.0
TH1_k127_1998819_2 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000005888 147.0
TH1_k127_1998819_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000006684 90.0
TH1_k127_2016013_0 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 331.0
TH1_k127_2016013_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000001642 140.0
TH1_k127_2041511_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1159.0
TH1_k127_2041511_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 379.0
TH1_k127_2041511_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 369.0
TH1_k127_2041511_3 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 343.0
TH1_k127_2041511_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 304.0
TH1_k127_2041511_5 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000003158 234.0
TH1_k127_2041511_6 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000001382 219.0
TH1_k127_2049629_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.38e-220 689.0
TH1_k127_2049629_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 451.0
TH1_k127_2049629_2 cytochrome C - - - 0.0000000000000000000000000000502 120.0
TH1_k127_2049629_3 Belongs to the 'phage' integrase family - - - 0.00003259 46.0
TH1_k127_2075389_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 535.0
TH1_k127_2075389_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 355.0
TH1_k127_2075389_11 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000005155 55.0
TH1_k127_2075389_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 299.0
TH1_k127_2075389_3 PFAM HhH-GPD family protein K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 289.0
TH1_k127_2075389_4 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001723 258.0
TH1_k127_2075389_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000001621 226.0
TH1_k127_2075389_6 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000001546 197.0
TH1_k127_2075389_7 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000002318 163.0
TH1_k127_2075389_8 Domain of unknown function (DUF4115) - - - 0.000000000000000000001082 103.0
TH1_k127_2125181_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 365.0
TH1_k127_2125181_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000006353 269.0
TH1_k127_2136915_0 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 365.0
TH1_k127_2136915_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080,K14082 - 2.1.1.246,2.1.1.247,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 352.0
TH1_k127_2136915_2 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000002579 166.0
TH1_k127_2136915_4 SMART von Willebrand factor type A - - - 0.00002032 57.0
TH1_k127_2136915_5 4Fe-4S binding domain - - - 0.0003677 49.0
TH1_k127_2145409_0 Conserved region in glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 504.0
TH1_k127_2145409_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 423.0
TH1_k127_2145409_2 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004346 271.0
TH1_k127_2170755_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 432.0
TH1_k127_2170755_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006738 237.0
TH1_k127_2170755_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000004823 220.0
TH1_k127_2170755_3 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000003409 208.0
TH1_k127_2170755_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000002578 115.0
TH1_k127_2176221_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.702e-209 659.0
TH1_k127_2176221_1 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 406.0
TH1_k127_2176221_2 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 372.0
TH1_k127_2176221_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 329.0
TH1_k127_2176221_4 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001215 284.0
TH1_k127_2176221_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000001092 249.0
TH1_k127_2176221_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000006377 181.0
TH1_k127_2176221_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000001024 178.0
TH1_k127_2176221_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000002062 162.0
TH1_k127_2176221_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000005949 84.0
TH1_k127_2221837_0 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001772 255.0
TH1_k127_2221837_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000001941 215.0
TH1_k127_2221837_2 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000001355 187.0
TH1_k127_2221837_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000004645 148.0
TH1_k127_2221837_4 FabA-like domain K02372 - 4.2.1.59 0.000000000000000000002606 98.0
TH1_k127_2221837_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000006928 96.0
TH1_k127_2260832_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.104e-320 1013.0
TH1_k127_2260832_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 456.0
TH1_k127_2260832_2 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 324.0
TH1_k127_2270136_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 511.0
TH1_k127_2285147_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 8.811e-215 678.0
TH1_k127_2285147_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 525.0
TH1_k127_2285147_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000008066 220.0
TH1_k127_2285147_3 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000004025 164.0
TH1_k127_2285147_4 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000004205 119.0
TH1_k127_2285147_5 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.0000537 52.0
TH1_k127_2334641_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.959e-212 669.0
TH1_k127_2334641_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 526.0
TH1_k127_2334641_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 503.0
TH1_k127_2334641_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 331.0
TH1_k127_2334641_4 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000001097 167.0
TH1_k127_2334641_5 Zincin-like metallopeptidase - - - 0.0001228 47.0
TH1_k127_2348196_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 601.0
TH1_k127_2348196_1 NADH-quinone oxidoreductase K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 594.0
TH1_k127_2348196_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 353.0
TH1_k127_2358692_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.196e-233 736.0
TH1_k127_2358692_1 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 329.0
TH1_k127_2358692_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 293.0
TH1_k127_2358692_3 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000962 162.0
TH1_k127_2358692_4 - - - - 0.00000000000000000000000003335 116.0
TH1_k127_2358692_5 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000002257 102.0
TH1_k127_2376270_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 593.0
TH1_k127_2376270_1 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000000000000000002283 147.0
TH1_k127_2376270_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000001891 83.0
TH1_k127_2376270_3 Predicted membrane protein (DUF2318) - - - 0.00003538 47.0
TH1_k127_2390822_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000006243 230.0
TH1_k127_2390822_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000215 156.0
TH1_k127_2390822_2 - - - - 0.0000000000000000000000002035 119.0
TH1_k127_2390822_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.0000000000000002449 86.0
TH1_k127_2419488_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 306.0
TH1_k127_2419488_1 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000005088 168.0
TH1_k127_2419488_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000005282 147.0
TH1_k127_2419488_3 Sulfurtransferase TusA - - - 0.00000000000000000001582 93.0
TH1_k127_2419488_4 peptidyl-tyrosine sulfation - - - 0.00000000001765 76.0
TH1_k127_2480810_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1101.0
TH1_k127_2480810_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.804e-199 627.0
TH1_k127_2480810_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000003775 126.0
TH1_k127_2480810_11 Thioredoxin-like - - - 0.00000000000000000000000000001801 123.0
TH1_k127_2480810_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 550.0
TH1_k127_2480810_3 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 537.0
TH1_k127_2480810_4 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 518.0
TH1_k127_2480810_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 396.0
TH1_k127_2480810_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 345.0
TH1_k127_2480810_7 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 323.0
TH1_k127_2480810_8 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685,K07053 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3,3.1.3.97 0.00000000000000000000000000000000000000000000000000294 192.0
TH1_k127_2480810_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000187 124.0
TH1_k127_2502336_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 573.0
TH1_k127_2502336_1 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 341.0
TH1_k127_2502336_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008932 265.0
TH1_k127_2502336_3 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000004156 176.0
TH1_k127_2502336_4 Protein of unknown function DUF86 - - - 0.000000000000000000000000002221 116.0
TH1_k127_2502336_5 Nucleotidyltransferase domain K07076 - - 0.00000000000001706 79.0
TH1_k127_2502336_6 - - - - 0.00000000001153 70.0
TH1_k127_2502336_7 Psort location OuterMembrane, score 9.95 K13735 - - 0.00001659 57.0
TH1_k127_2505369_0 SMART Elongator protein 3 MiaB NifB - - - 3.667e-211 683.0
TH1_k127_2505369_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 604.0
TH1_k127_2505369_2 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 286.0
TH1_k127_2505369_3 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.000000000000000000000000005388 110.0
TH1_k127_2505369_4 COG1522 Transcriptional regulators - - - 0.0001461 47.0
TH1_k127_2511768_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1242.0
TH1_k127_2511768_1 K transport systems K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 365.0
TH1_k127_2511768_2 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002668 263.0
TH1_k127_2511768_3 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000009727 132.0
TH1_k127_2522527_0 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 448.0
TH1_k127_2522527_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 332.0
TH1_k127_2522527_2 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 314.0
TH1_k127_2522527_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000008635 217.0
TH1_k127_254140_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 314.0
TH1_k127_254140_1 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002105 268.0
TH1_k127_254140_2 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000223 269.0
TH1_k127_254140_3 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000008475 96.0
TH1_k127_254140_4 STAS domain K04749 - - 0.000000000000000002085 89.0
TH1_k127_254140_5 MlaD protein K02067,K06192 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016043,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0120009 - 0.000000000000947 76.0
TH1_k127_254140_6 - - - - 0.000000004948 62.0
TH1_k127_255247_0 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000012 179.0
TH1_k127_255247_1 fimbrial assembly K02461 - - 0.000000004029 69.0
TH1_k127_2749518_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 506.0
TH1_k127_2749518_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 436.0
TH1_k127_2749518_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 361.0
TH1_k127_2749518_3 SMART helicase c2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 364.0
TH1_k127_2749518_4 shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000009004 158.0
TH1_k127_2749518_5 - - - - 0.00000000000000103 80.0
TH1_k127_2749518_6 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00003229 52.0
TH1_k127_2769161_0 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 367.0
TH1_k127_2769161_1 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 335.0
TH1_k127_2769161_10 - K07092 - - 0.0009685 48.0
TH1_k127_2769161_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000097 286.0
TH1_k127_2769161_3 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000000000000003206 198.0
TH1_k127_2769161_4 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000004022 163.0
TH1_k127_2769161_5 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000002515 149.0
TH1_k127_2769161_6 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000004443 119.0
TH1_k127_2769161_7 OsmC-like protein - - - 0.000000000000000000000006837 108.0
TH1_k127_2769161_8 Ornithine decarboxylase inhibitor-putative sigma54 transciptional regulator K02584 - - 0.0000000003932 62.0
TH1_k127_2769161_9 cheY-homologous receiver domain - - - 0.00007506 50.0
TH1_k127_2771398_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 473.0
TH1_k127_2771398_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 340.0
TH1_k127_2771398_2 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000139 212.0
TH1_k127_2771398_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000007687 158.0
TH1_k127_2771398_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000005633 63.0
TH1_k127_2774306_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 327.0
TH1_k127_2774306_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 323.0
TH1_k127_2774306_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009512 249.0
TH1_k127_2774306_3 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000006884 216.0
TH1_k127_2774306_4 MOSC domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000006603 216.0
TH1_k127_2774306_5 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000007914 168.0
TH1_k127_2774306_6 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000006061 133.0
TH1_k127_2774306_8 Regulatory protein, FmdB family - - - 0.0000000000000000000005607 96.0
TH1_k127_2774306_9 Mycolic acid cyclopropane synthetase - - - 0.00000000000008941 70.0
TH1_k127_2786528_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 330.0
TH1_k127_2786528_1 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001217 271.0
TH1_k127_2786528_2 PDGLE domain K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004214 247.0
TH1_k127_2794989_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 287.0
TH1_k127_2794989_2 - - - - 0.00000000000001875 78.0
TH1_k127_2820489_0 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22341 - 1.17.1.11,1.17.1.9 3.084e-199 634.0
TH1_k127_2820489_1 Pyridine nucleotide-disulphide oxidoreductase K15022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 554.0
TH1_k127_2820489_2 2Fe-2S iron-sulfur cluster binding domain K05299 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 402.0
TH1_k127_2820489_3 photosystem II stabilization K02237 - - 0.0000000000000000000000000000000000000000000000001963 188.0
TH1_k127_2820489_4 - - - - 0.000000000000000000000000000005042 121.0
TH1_k127_2820489_5 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000004398 88.0
TH1_k127_2834579_0 Methyltransferase type 11 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 457.0
TH1_k127_2834579_1 ABC-2 type transporter K09688,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 300.0
TH1_k127_2834579_2 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001725 267.0
TH1_k127_2834579_3 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000573 224.0
TH1_k127_2834579_4 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000001589 189.0
TH1_k127_2852033_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 7.839e-225 707.0
TH1_k127_2852033_1 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001008 251.0
TH1_k127_2852033_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000004796 67.0
TH1_k127_2852901_0 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 420.0
TH1_k127_2852901_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 391.0
TH1_k127_2852901_10 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000007145 111.0
TH1_k127_2852901_11 Protein of unknown function (DUF507) - - - 0.000000000000000000000001212 106.0
TH1_k127_2852901_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000001202 102.0
TH1_k127_2852901_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 287.0
TH1_k127_2852901_3 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002957 251.0
TH1_k127_2852901_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000002125 229.0
TH1_k127_2852901_5 Pfam:TPM K08988 - - 0.000000000000000000000000000000000000000000000000000000002441 207.0
TH1_k127_2852901_6 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000205 192.0
TH1_k127_2852901_7 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000001219 176.0
TH1_k127_2852901_8 HNH nucleases - - - 0.00000000000000000000000000000000000001675 145.0
TH1_k127_2852901_9 Protein of unknown function (DUF507) - - - 0.00000000000000000000000003384 111.0
TH1_k127_2853307_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000519 196.0
TH1_k127_2853307_1 GDSL-like Lipase/Acylhydrolase - - - 0.000000002526 68.0
TH1_k127_2856846_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.125e-233 739.0
TH1_k127_2856846_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 376.0
TH1_k127_2856846_2 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001651 253.0
TH1_k127_2856846_3 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001931 248.0
TH1_k127_2856846_4 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000002499 165.0
TH1_k127_2856846_5 Rdx family K07401 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009898,GO:0010941,GO:0016020,GO:0030334,GO:0030335,GO:0031224,GO:0031226,GO:0031235,GO:0031344,GO:0031346,GO:0032879,GO:0040012,GO:0040017,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0044087,GO:0044089,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051270,GO:0051272,GO:0051489,GO:0051491,GO:0060491,GO:0060548,GO:0065007,GO:0071944,GO:0098552,GO:0098562,GO:0120032,GO:0120034,GO:0120035,GO:2000145,GO:2000147 - 0.000001777 55.0
TH1_k127_2859874_0 - - - - 1.243e-194 614.0
TH1_k127_2859874_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000007688 255.0
TH1_k127_2859874_2 FMN reductase (NADPH) activity - - - 0.000000000000000000000000000000000000000000000000000003365 198.0
TH1_k127_2859874_3 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000001269 64.0
TH1_k127_2863992_0 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000001765 236.0
TH1_k127_2863992_1 epimerase - - - 0.000003861 51.0
TH1_k127_2879092_0 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000107 283.0
TH1_k127_2879092_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000957 67.0
TH1_k127_2894751_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 330.0
TH1_k127_2894751_1 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000002585 143.0
TH1_k127_2894751_2 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001056 108.0
TH1_k127_2894751_3 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000002068 104.0
TH1_k127_2894751_4 - - - - 0.000000000000000000000009703 103.0
TH1_k127_2894751_5 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00001442 49.0
TH1_k127_2944949_0 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 406.0
TH1_k127_2944949_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006914 268.0
TH1_k127_2944949_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000002217 173.0
TH1_k127_2944949_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000005709 66.0
TH1_k127_2965244_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000001685 173.0
TH1_k127_2965244_2 Bacterial protein of unknown function (DUF937) - - - 0.000000000001504 68.0
TH1_k127_2965244_4 PilZ domain - - - 0.00003375 50.0
TH1_k127_2985423_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1230.0
TH1_k127_2985423_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 549.0
TH1_k127_2985423_10 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.0000000000000000000000000000000000000000003739 163.0
TH1_k127_2985423_11 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000001555 167.0
TH1_k127_2985423_12 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000001285 122.0
TH1_k127_2985423_13 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000001381 100.0
TH1_k127_2985423_14 Uroporphyrinogen decarboxylase (URO-D) K14082 - 2.1.1.247 0.000000000000000009525 85.0
TH1_k127_2985423_2 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 497.0
TH1_k127_2985423_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 474.0
TH1_k127_2985423_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 385.0
TH1_k127_2985423_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 365.0
TH1_k127_2985423_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 349.0
TH1_k127_2985423_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
TH1_k127_2985423_8 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.00000000000000000000000000000000000000000000000000002954 197.0
TH1_k127_2985423_9 transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000001052 180.0
TH1_k127_3005644_0 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 5.663e-212 663.0
TH1_k127_3005644_1 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 597.0
TH1_k127_3005644_10 lyase activity - - - 0.00000000000000006969 85.0
TH1_k127_3005644_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 516.0
TH1_k127_3005644_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 350.0
TH1_k127_3005644_4 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 299.0
TH1_k127_3005644_5 Tetratricopeptide repeat K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002316 254.0
TH1_k127_3005644_6 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000003513 180.0
TH1_k127_3005644_7 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000003596 175.0
TH1_k127_3005644_8 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.0000000000000000000000000000000000000001128 158.0
TH1_k127_3005644_9 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000002597 140.0
TH1_k127_305352_0 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 453.0
TH1_k127_305352_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 283.0
TH1_k127_305352_2 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003164 279.0
TH1_k127_305352_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000001781 205.0
TH1_k127_305352_4 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000004166 144.0
TH1_k127_3099591_0 Elongation factor G, domain IV K02355 - - 3.615e-310 965.0
TH1_k127_3099591_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.268e-254 803.0
TH1_k127_3099591_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 3.779e-232 734.0
TH1_k127_3099591_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 449.0
TH1_k127_3099591_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000008271 266.0
TH1_k127_3099591_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000006955 146.0
TH1_k127_3099591_6 Protein-disulfide isomerase - - - 0.00000000000000000000000000009902 120.0
TH1_k127_3099591_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000002121 100.0
TH1_k127_3099591_8 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.0000002204 58.0
TH1_k127_3099591_9 DSBA-like thioredoxin domain - - - 0.00003488 50.0
TH1_k127_3127853_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 8.706e-200 629.0
TH1_k127_3127853_1 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000000000000001249 203.0
TH1_k127_3127853_2 Glycine-zipper domain - - - 0.00000000000000000000001028 107.0
TH1_k127_3127853_3 - - - - 0.00000000000000000008694 95.0
TH1_k127_3138319_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1114.0
TH1_k127_3138319_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 325.0
TH1_k127_3138319_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000008866 78.0
TH1_k127_3168547_0 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 515.0
TH1_k127_3168547_1 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 491.0
TH1_k127_3168547_2 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 327.0
TH1_k127_3168547_3 [acyl-carrier-protein] S-malonyltransferase activity K00645,K15327,K15329,K15355,K15469 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 307.0
TH1_k127_3168547_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000003277 169.0
TH1_k127_3168547_5 - - - - 0.000000000001245 73.0
TH1_k127_3185054_0 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 442.0
TH1_k127_3185054_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000003111 264.0
TH1_k127_3185054_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000004365 150.0
TH1_k127_3185054_3 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000007414 128.0
TH1_k127_3185413_0 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 460.0
TH1_k127_3185413_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 355.0
TH1_k127_3185413_2 tRNA modification K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000000003667 224.0
TH1_k127_3185413_3 Universal stress protein family - - - 0.0000000000001963 76.0
TH1_k127_3185413_4 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000007591 57.0
TH1_k127_3186162_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 523.0
TH1_k127_3186162_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 359.0
TH1_k127_3186162_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000007301 258.0
TH1_k127_3186162_3 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000001542 134.0
TH1_k127_3186162_4 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000003674 135.0
TH1_k127_3186162_5 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000002589 117.0
TH1_k127_3192741_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 526.0
TH1_k127_3192741_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 447.0
TH1_k127_3192741_10 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000003158 72.0
TH1_k127_3192741_2 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 386.0
TH1_k127_3192741_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 370.0
TH1_k127_3192741_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 341.0
TH1_k127_3192741_5 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000003075 226.0
TH1_k127_3192741_6 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000001286 180.0
TH1_k127_3192741_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000003162 145.0
TH1_k127_3192741_8 protein complex oligomerization - - - 0.000000000000000000000000000002831 126.0
TH1_k127_3192741_9 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000000004718 115.0
TH1_k127_3198992_0 Ftsk_gamma K03466 - - 2.838e-200 646.0
TH1_k127_3198992_1 PFAM glycoside hydrolase family 3 domain protein K01207,K05349 - 3.2.1.21,3.2.1.52 0.00000000000000000000000000000000000000000000000000000006498 211.0
TH1_k127_3198992_2 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000005406 72.0
TH1_k127_3198992_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000002753 52.0
TH1_k127_3209729_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 357.0
TH1_k127_3209729_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 339.0
TH1_k127_3209729_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000001269 64.0
TH1_k127_321703_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001773 267.0
TH1_k127_321703_1 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003412 247.0
TH1_k127_321703_2 PFAM amidohydrolase - - - 0.00000000000000000000005003 111.0
TH1_k127_3233964_0 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000001582 240.0
TH1_k127_3252300_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 295.0
TH1_k127_3252300_1 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 263.0
TH1_k127_329994_0 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 551.0
TH1_k127_329994_1 ABC transporter K09972,K10038 - - 0.0000000000000000000000000000000000001202 145.0
TH1_k127_329994_2 PFAM Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000003768 123.0
TH1_k127_3349809_0 KAP family P-loop domain - - - 5.435e-216 681.0
TH1_k127_3349809_1 Domain of unknown function (DUF1788) - - - 0.000000000000000000000000000000000000000000000000000000000003624 214.0
TH1_k127_3349809_2 Putative inner membrane protein (DUF1819) - - - 0.00000000000000000000354 97.0
TH1_k127_3385058_0 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 392.0
TH1_k127_3385058_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 322.0
TH1_k127_3385058_2 Nitroreductase family K04719 - 1.13.11.79 0.00000000000000000000000000000000000000000000000000000000000000001578 227.0
TH1_k127_3385058_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000006442 110.0
TH1_k127_3385058_4 PFAM thioesterase superfamily K02614 - - 0.0000000000000001583 84.0
TH1_k127_3404391_0 COG0058 Glucan phosphorylase - - - 1.354e-256 802.0
TH1_k127_3404391_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 451.0
TH1_k127_3404391_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 422.0
TH1_k127_3404391_3 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 415.0
TH1_k127_3404391_4 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 380.0
TH1_k127_3404391_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000006512 132.0
TH1_k127_3404391_6 nuclease activity K06218 - - 0.000000000000000000001114 96.0
TH1_k127_3419528_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000003262 154.0
TH1_k127_3419528_1 Protein of unknown function (DUF433) - - - 0.00000000000785 66.0
TH1_k127_3427391_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 478.0
TH1_k127_3427391_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 395.0
TH1_k127_3427391_2 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 385.0
TH1_k127_3427391_3 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 344.0
TH1_k127_3427391_4 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002557 288.0
TH1_k127_3427391_5 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000004452 165.0
TH1_k127_3427391_6 iron-sulfur cluster assembly - - - 0.000000000000000000000004478 102.0
TH1_k127_3427391_7 Probable molybdopterin binding domain - - - 0.000000000000000008526 82.0
TH1_k127_3427391_8 ATPase (AAA superfamily K07133 - - 0.000000000001224 68.0
TH1_k127_3427391_9 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.000000000001548 76.0
TH1_k127_3472598_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1031.0
TH1_k127_3472598_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 3.249e-251 789.0
TH1_k127_3472598_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 9.675e-222 706.0
TH1_k127_3472598_3 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 499.0
TH1_k127_3472598_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000008799 93.0
TH1_k127_3473539_0 Psort location CytoplasmicMembrane, score K01990,K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009665 275.0
TH1_k127_3473539_1 PFAM phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000002642 233.0
TH1_k127_3473539_2 Sulfatase - - - 0.00000000000000000000000003289 125.0
TH1_k127_3536355_0 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 398.0
TH1_k127_3536355_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 383.0
TH1_k127_3536355_10 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.0000000000000000000001198 101.0
TH1_k127_3536355_11 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000008331 105.0
TH1_k127_3536355_12 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000001771 94.0
TH1_k127_3536355_13 Tetratricopeptide repeat-like domain - - - 0.0000000005468 67.0
TH1_k127_3536355_14 protein involved in the oxidation of intracellular sulfur K07236 - - 0.00000003487 59.0
TH1_k127_3536355_15 sulfur relay protein TusB DsrH K07237 - - 0.0007114 47.0
TH1_k127_3536355_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 330.0
TH1_k127_3536355_3 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 319.0
TH1_k127_3536355_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006157 265.0
TH1_k127_3536355_5 zinc ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000167 246.0
TH1_k127_3536355_6 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000007157 184.0
TH1_k127_3536355_7 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000002922 118.0
TH1_k127_3536355_8 Tetratricopeptide repeat - - - 0.0000000000000000000000002709 113.0
TH1_k127_3536355_9 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000001819 106.0
TH1_k127_3559599_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 541.0
TH1_k127_3578843_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 438.0
TH1_k127_3578843_1 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 289.0
TH1_k127_3578843_2 heat shock protein binding K05516,K05801 - - 0.00000000000000000000003388 112.0
TH1_k127_358572_0 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 1.277e-247 788.0
TH1_k127_358572_1 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 576.0
TH1_k127_358572_2 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 293.0
TH1_k127_358572_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001491 258.0
TH1_k127_358572_4 Biogenesis protein K09792 - - 0.0000000000000000000000000000000000000000000000000000000000007975 218.0
TH1_k127_358572_5 FixH - - - 0.000000000000000000000000007517 114.0
TH1_k127_358572_6 FixH - - - 0.0000000000000004167 84.0
TH1_k127_358572_7 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.0000000000003174 70.0
TH1_k127_3658003_0 Flavodoxin - - - 1.132e-208 655.0
TH1_k127_3658003_1 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000002539 179.0
TH1_k127_3658003_2 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000002769 190.0
TH1_k127_3658003_3 PFAM Rubrerythrin - - - 0.00000000000000000000000000006888 117.0
TH1_k127_3677065_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 402.0
TH1_k127_3677065_1 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 331.0
TH1_k127_3677065_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000007041 204.0
TH1_k127_3677065_3 - - - - 0.00000005661 60.0
TH1_k127_3677065_4 cheY-homologous receiver domain - - - 0.000006351 53.0
TH1_k127_3703410_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009704 282.0
TH1_k127_3703410_1 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000006164 244.0
TH1_k127_3703410_2 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000008366 157.0
TH1_k127_3703410_3 phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000005836 147.0
TH1_k127_3734670_0 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 381.0
TH1_k127_3734670_1 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000003372 207.0
TH1_k127_3734670_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001872 198.0
TH1_k127_3734670_3 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000002168 156.0
TH1_k127_3734670_4 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000004627 142.0
TH1_k127_3755236_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 9.664e-211 660.0
TH1_k127_3755236_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.323e-202 634.0
TH1_k127_3755236_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 398.0
TH1_k127_3755236_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 335.0
TH1_k127_3755236_4 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001941 286.0
TH1_k127_3755236_5 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000001544 179.0
TH1_k127_3755236_6 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000019 156.0
TH1_k127_3755236_7 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000002922 100.0
TH1_k127_3760185_0 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 574.0
TH1_k127_3760185_1 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 417.0
TH1_k127_3768266_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 426.0
TH1_k127_3768266_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 356.0
TH1_k127_3768266_2 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 308.0
TH1_k127_3768266_3 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000004392 221.0
TH1_k127_3768266_4 Histidine kinase - - - 0.000000000000000000000000000008546 132.0
TH1_k127_3768266_5 Class III cytochrome C family - - - 0.00000000007622 71.0
TH1_k127_3800847_0 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000002322 170.0
TH1_k127_3800847_1 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000256 122.0
TH1_k127_3804207_0 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 523.0
TH1_k127_3804207_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 440.0
TH1_k127_3804207_2 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 407.0
TH1_k127_3804207_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 244.0
TH1_k127_3804207_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000007762 173.0
TH1_k127_3835031_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 363.0
TH1_k127_3840202_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 519.0
TH1_k127_3840202_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 422.0
TH1_k127_3840202_2 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 396.0
TH1_k127_3840202_3 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 387.0
TH1_k127_3840202_4 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 303.0
TH1_k127_3840202_5 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000001218 99.0
TH1_k127_3840202_6 - - - - 0.00000000000001927 77.0
TH1_k127_3840202_7 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0000000006594 68.0
TH1_k127_3854406_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1303.0
TH1_k127_3854406_1 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006694 270.0
TH1_k127_3854406_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000006461 222.0
TH1_k127_3854406_3 methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000002432 221.0
TH1_k127_3888865_0 glycosyl transferase family 2 K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001864 261.0
TH1_k127_3888865_1 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000562 244.0
TH1_k127_3888865_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000006733 164.0
TH1_k127_3888865_3 Sulfatase - - - 0.000000000000000000000006175 118.0
TH1_k127_3888865_4 transferase activity, transferring glycosyl groups K13658 - 2.4.1.251 0.000000001669 66.0
TH1_k127_3919078_0 Holliday junction DNA helicase ruvB N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 379.0
TH1_k127_3980491_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 4.071e-222 697.0
TH1_k127_3980491_1 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 494.0
TH1_k127_3980491_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 407.0
TH1_k127_4029085_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 7.774e-230 729.0
TH1_k127_4029085_1 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 357.0
TH1_k127_4029085_10 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000000000001836 194.0
TH1_k127_4029085_11 Fe-S oxidoreductase - - - 0.00000000000000000000002124 110.0
TH1_k127_4029085_12 - - - - 0.0000000000009422 74.0
TH1_k127_4029085_2 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 316.0
TH1_k127_4029085_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 323.0
TH1_k127_4029085_4 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 310.0
TH1_k127_4029085_5 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 308.0
TH1_k127_4029085_6 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 296.0
TH1_k127_4029085_7 Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 305.0
TH1_k127_4029085_8 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001498 276.0
TH1_k127_4029085_9 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001062 262.0
TH1_k127_4065139_0 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 445.0
TH1_k127_4065139_1 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 359.0
TH1_k127_4065139_3 gag-polyprotein putative aspartyl protease K06985 - - 0.0000000000932 70.0
TH1_k127_4074865_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 603.0
TH1_k127_4074865_1 B3/4 domain K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 432.0
TH1_k127_4079639_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 320.0
TH1_k127_4079639_1 HEAT repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001905 292.0
TH1_k127_4079639_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000003233 243.0
TH1_k127_4079639_3 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000188 233.0
TH1_k127_4079639_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000004757 169.0
TH1_k127_4079639_5 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000001365 130.0
TH1_k127_4079639_6 PFAM CheW domain protein K03408 - - 0.000001267 53.0
TH1_k127_4095433_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.101e-217 692.0
TH1_k127_4095433_1 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001073 263.0
TH1_k127_4095433_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000004896 169.0
TH1_k127_4108525_0 NADH-quinone oxidoreductase K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 429.0
TH1_k127_4108525_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 331.0
TH1_k127_4108525_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000002937 201.0
TH1_k127_4108525_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000005248 153.0
TH1_k127_4108525_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000002678 122.0
TH1_k127_4131575_0 sister chromatid segregation - - - 1.8e-209 662.0
TH1_k127_4131575_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003075 271.0
TH1_k127_4131575_2 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000002305 132.0
TH1_k127_4140364_0 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 345.0
TH1_k127_4140364_1 Domain of unknown function (DUF3786) - - - 0.000000000000000007306 91.0
TH1_k127_4140364_2 Transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' - - - 0.00000000000009111 71.0
TH1_k127_4180974_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.882e-276 869.0
TH1_k127_4180974_1 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000001764 177.0
TH1_k127_4180974_2 ATP synthase, subunit b - - - 0.000001171 54.0
TH1_k127_4231084_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1153.0
TH1_k127_4231084_1 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000001413 256.0
TH1_k127_4231084_2 energy transducer activity K03832 - - 0.00000000000000000000000000000000000000000000003719 181.0
TH1_k127_4231084_3 proteolysis K03665 - - 0.0000000000000000000000000001331 121.0
TH1_k127_4231084_4 Universal stress protein K06149 - - 0.000000000000000000003779 95.0
TH1_k127_4242363_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 416.0
TH1_k127_4242363_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 383.0
TH1_k127_4242363_2 PINc domain ribonuclease K09006 - - 0.000000000000000000000000000000000000000000000000000000000000006986 226.0
TH1_k127_4242363_3 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000005875 205.0
TH1_k127_4242363_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000000063 185.0
TH1_k127_4242363_5 - - - - 0.00000000000000000000000000000000000000000000001211 173.0
TH1_k127_4242363_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000005575 175.0
TH1_k127_4242363_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000005589 149.0
TH1_k127_42981_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 7.908e-241 767.0
TH1_k127_42981_1 cysteine-tRNA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 452.0
TH1_k127_42981_10 - - - - 0.00000000000000000000000000000000000009978 153.0
TH1_k127_42981_11 Amidohydrolase - - - 0.0000000000000000000000000000000000003739 149.0
TH1_k127_42981_12 manually curated - - - 0.0000000000000000000000000000001115 125.0
TH1_k127_42981_13 cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000002377 104.0
TH1_k127_42981_14 gas vesicle protein - - - 0.000000000000000000001808 98.0
TH1_k127_42981_15 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000002333 96.0
TH1_k127_42981_16 - - - - 0.000000000000000001257 87.0
TH1_k127_42981_2 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 424.0
TH1_k127_42981_3 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 423.0
TH1_k127_42981_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 342.0
TH1_k127_42981_5 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 305.0
TH1_k127_42981_6 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002074 285.0
TH1_k127_42981_7 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000005562 273.0
TH1_k127_42981_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001513 256.0
TH1_k127_42981_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000008233 228.0
TH1_k127_4310552_0 AAA domain - - - 0.0 1077.0
TH1_k127_4310552_1 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 465.0
TH1_k127_4310552_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 434.0
TH1_k127_4310552_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 319.0
TH1_k127_4310552_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008483 280.0
TH1_k127_4310552_5 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000004013 184.0
TH1_k127_4310552_6 RNase_H superfamily K07502 - - 0.0000000000000000000000000000001252 126.0
TH1_k127_4310552_7 - - - - 0.0000000000000000000000000003686 119.0
TH1_k127_4310552_8 TfoX N-terminal domain - - - 0.000000000000003557 79.0
TH1_k127_4310552_9 Glucose-1-phosphate thymidylyltransferase K00973 - 2.7.7.24 0.0000000004252 62.0
TH1_k127_4311804_0 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 350.0
TH1_k127_4311804_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 343.0
TH1_k127_4311804_2 - - - - 0.000000000000000000000000000000000000000000000003843 184.0
TH1_k127_4311804_3 lyase activity - - - 0.0000000000000000000001418 108.0
TH1_k127_4321856_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 449.0
TH1_k127_4321856_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000001404 181.0
TH1_k127_4333957_0 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 481.0
TH1_k127_4333957_1 spermidine synthase activity - - - 0.00000000000000000000000000000000000000000000000001614 192.0
TH1_k127_4333957_2 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000000000000000001185 154.0
TH1_k127_4333957_3 Methyltransferase FkbM domain - - - 0.000000004025 60.0
TH1_k127_4380197_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 303.0
TH1_k127_4380197_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000001877 250.0
TH1_k127_4380197_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000002975 190.0
TH1_k127_4380197_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000003047 182.0
TH1_k127_4380197_4 PFAM CBS domain - - - 0.00000000000000000000000000000000000000116 152.0
TH1_k127_4380197_5 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000003996 119.0
TH1_k127_4380197_6 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000005171 85.0
TH1_k127_4412068_0 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000568 216.0
TH1_k127_4412068_1 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000004392 164.0
TH1_k127_4412068_2 Aminoglycoside phosphotransferase - - - 0.00004065 55.0
TH1_k127_4413_0 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 327.0
TH1_k127_4413_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002908 285.0
TH1_k127_4413_2 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000004988 242.0
TH1_k127_4413_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000001471 215.0
TH1_k127_4413_4 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000003695 192.0
TH1_k127_4413_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000003781 49.0
TH1_k127_4453811_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 299.0
TH1_k127_4453811_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000006764 179.0
TH1_k127_4453811_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 0.0000000003932 62.0
TH1_k127_4462257_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1566.0
TH1_k127_4462257_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 476.0
TH1_k127_4462257_2 PFAM phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 308.0
TH1_k127_4467948_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 3.276e-296 926.0
TH1_k127_4467948_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001636 240.0
TH1_k127_4467948_2 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000008031 243.0
TH1_k127_4467948_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000503 222.0
TH1_k127_4467948_4 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000002395 172.0
TH1_k127_4467948_5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000002293 166.0
TH1_k127_4467948_6 Glutaredoxin - - - 0.000000000000000005384 93.0
TH1_k127_4467948_7 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000001264 78.0
TH1_k127_4467948_8 Bacterial regulatory proteins, crp family K01420 - - 0.000000000006214 75.0
TH1_k127_4467948_9 Domain of unknown function (DUF4124) - - - 0.00001111 55.0
TH1_k127_448931_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.814e-199 627.0
TH1_k127_448931_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 327.0
TH1_k127_448931_2 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000004799 221.0
TH1_k127_448931_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000158 164.0
TH1_k127_4490290_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 9.435e-248 773.0
TH1_k127_4490290_1 Cell Wall K01448 - 3.5.1.28 0.000008177 57.0
TH1_k127_4492865_0 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 555.0
TH1_k127_4492865_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 365.0
TH1_k127_4492865_2 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 299.0
TH1_k127_4492865_3 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008607 259.0
TH1_k127_4492865_4 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000001695 218.0
TH1_k127_4492865_5 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001193 224.0
TH1_k127_4492865_6 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000001795 217.0
TH1_k127_4492865_7 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 0.000000000000000000000000000000000000000000000004736 185.0
TH1_k127_4492865_8 - - - - 0.00000000000000000001524 99.0
TH1_k127_4514423_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 491.0
TH1_k127_4514423_1 - - - - 0.0000003943 54.0
TH1_k127_453438_0 FAD binding domain K00278 - 1.4.3.16 6.365e-202 641.0
TH1_k127_453438_1 nuclear chromosome segregation - - - 0.000000000000000000000000007883 118.0
TH1_k127_4565291_0 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000001228 162.0
TH1_k127_4565291_1 lyase activity - - - 0.0000000000000000000000000000000001085 151.0
TH1_k127_4585081_0 Transcriptional regulatory protein, C terminal K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001979 248.0
TH1_k127_4585081_1 phosphatidate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001734 239.0
TH1_k127_4585081_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000001649 211.0
TH1_k127_4585081_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000001372 178.0
TH1_k127_4585081_4 YacP-like NYN domain K06962 - - 0.00000000000000000000000001527 116.0
TH1_k127_4589741_0 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000001521 224.0
TH1_k127_4589741_1 PFAM YicC-like family, N-terminal region - - - 0.000000000000000000000000000000000006644 143.0
TH1_k127_4589741_2 Domain of unknown function (DUF370) K09777 - - 0.00000000000000000000000000000438 123.0
TH1_k127_4589741_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000002 52.0
TH1_k127_4632966_0 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 288.0
TH1_k127_4632966_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000177 223.0
TH1_k127_4632966_2 OstA-like protein K09774 - - 0.000000000000000000000000000003321 126.0
TH1_k127_4642100_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 563.0
TH1_k127_4642100_1 4 iron, 4 sulfur cluster binding K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 356.0
TH1_k127_4642100_2 - - - - 0.00000000000000000000000000000000000000000000000002754 181.0
TH1_k127_4642100_3 Universal stress protein family - - - 0.0000000000000000000000000000000000003584 145.0
TH1_k127_464913_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.98e-212 684.0
TH1_k127_464913_1 Domain of unknown function (DUF296) - - - 0.0000000000000000000000000000000000000000000000000000000000432 208.0
TH1_k127_464913_2 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000000007947 190.0
TH1_k127_464913_3 Nitroreductase family K04719 - 1.13.11.79 0.000000008684 56.0
TH1_k127_4654930_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009982 597.0
TH1_k127_4654930_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 587.0
TH1_k127_4654930_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 421.0
TH1_k127_4654930_3 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 407.0
TH1_k127_4654930_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000008027 260.0
TH1_k127_4654930_5 His Kinase A (phosphoacceptor) domain K10715 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000001134 259.0
TH1_k127_4654930_6 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000002796 225.0
TH1_k127_4737490_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.159e-221 692.0
TH1_k127_4737490_1 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 340.0
TH1_k127_4766020_0 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 340.0
TH1_k127_4766020_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 328.0
TH1_k127_4779492_0 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 471.0
TH1_k127_4779492_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 399.0
TH1_k127_4779492_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 331.0
TH1_k127_4779492_3 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000002539 160.0
TH1_k127_4779492_4 OsmC-like protein K07397 - - 0.00000000000000000001636 97.0
TH1_k127_4779492_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000001857 90.0
TH1_k127_4779492_6 Belongs to the UPF0235 family K09131 - - 0.0000000000000008412 79.0
TH1_k127_4793609_0 FMN binding - - - 8.855e-273 845.0
TH1_k127_4793609_1 PFAM ferredoxin-dependent glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 422.0
TH1_k127_4793609_2 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000039 287.0
TH1_k127_4814813_0 Epimerase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 313.0
TH1_k127_4814813_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000003093 165.0
TH1_k127_4814813_4 Putative prokaryotic signal transducing protein - - - 0.00001132 51.0
TH1_k127_4824507_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 353.0
TH1_k127_4824507_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000002669 237.0
TH1_k127_4824507_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000007044 220.0
TH1_k127_4831072_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.654e-210 659.0
TH1_k127_4831072_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 468.0
TH1_k127_4831072_2 ACT domain - - - 0.00000000000000000000000000000000000000000000000000000000005134 207.0
TH1_k127_4831072_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000583 196.0
TH1_k127_4831072_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000007978 130.0
TH1_k127_4849432_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000003613 142.0
TH1_k127_4849432_1 Protein of unknown function (DUF3187) - - - 0.00000000000000000000002174 111.0
TH1_k127_4849432_2 - - - - 0.0005507 48.0
TH1_k127_4886897_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009279 282.0
TH1_k127_4886897_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000001639 137.0
TH1_k127_4886897_2 Cytochrome c3 - - - 0.0000000000000000000001715 100.0
TH1_k127_4886897_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000001871 100.0
TH1_k127_4909857_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 441.0
TH1_k127_4909857_1 Histidine kinase K07642,K18143 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 372.0
TH1_k127_4909857_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 302.0
TH1_k127_4909857_3 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 267.0
TH1_k127_4909857_4 VanZ like family - - - 0.0000000000000000000000000000000000000000000006439 170.0
TH1_k127_4909857_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000002122 155.0
TH1_k127_4909857_6 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000005918 123.0
TH1_k127_4909857_7 - - - - 0.0000004804 57.0
TH1_k127_495621_0 General secretory system II, protein E domain protein K02454 - - 6.523e-199 636.0
TH1_k127_495621_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 512.0
TH1_k127_495621_2 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002648 257.0
TH1_k127_495621_3 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000003225 174.0
TH1_k127_495621_4 family 9 - - - 0.0000000000000000000000000000000005767 138.0
TH1_k127_495621_5 Nitroreductase family - - - 0.00000000000000000000001827 104.0
TH1_k127_495621_6 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000002397 63.0
TH1_k127_5014328_0 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 398.0
TH1_k127_5014328_1 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000002428 191.0
TH1_k127_5033458_0 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000001829 158.0
TH1_k127_5033458_2 cytochrome complex assembly - - - 0.0000000000000000000000000000388 127.0
TH1_k127_5033458_3 PIN domain - - - 0.000000000000000000000005787 106.0
TH1_k127_5033458_4 cytochrome c biogenesis protein - - - 0.00000004619 60.0
TH1_k127_5033458_5 CopG domain protein DNA-binding domain protein - - - 0.0002564 48.0
TH1_k127_5035760_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 570.0
TH1_k127_5035760_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 352.0
TH1_k127_5035760_2 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000002266 231.0
TH1_k127_5155558_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1031.0
TH1_k127_5155558_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000001362 250.0
TH1_k127_5155558_2 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000002221 116.0
TH1_k127_5155558_3 NusG domain II - - - 0.0000000003586 66.0
TH1_k127_5160309_0 lipopolysaccharide biosynthesis K20998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 366.0
TH1_k127_5160309_1 polysaccharide K01991,K20987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 347.0
TH1_k127_5160309_2 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 297.0
TH1_k127_5160309_3 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004336 279.0
TH1_k127_5160309_4 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001707 256.0
TH1_k127_5160309_5 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000619 205.0
TH1_k127_5160309_6 AAA domain K16554 - - 0.000000000000000000000000000000000000000000000000002443 190.0
TH1_k127_5160309_7 PFAM Glycosyl transferase family 2 - - - 0.00000002067 60.0
TH1_k127_5168219_0 Elongation factor SelB, winged helix K03833 - - 1.262e-210 672.0
TH1_k127_5168219_1 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 509.0
TH1_k127_5188935_0 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004648 277.0
TH1_k127_5188935_1 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000515 220.0
TH1_k127_5188935_2 HNH nucleases - - - 0.00000000000000000000000000000000000000000004036 162.0
TH1_k127_5188935_3 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000003421 146.0
TH1_k127_5188935_4 Psort location Cytoplasmic, score 8.96 - - - 0.00000000009534 65.0
TH1_k127_5223267_0 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 308.0
TH1_k127_5223267_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000006992 103.0
TH1_k127_5223267_2 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000005564 75.0
TH1_k127_5227097_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 529.0
TH1_k127_5227097_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000009615 250.0
TH1_k127_5227097_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000001285 177.0
TH1_k127_5232745_0 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005112 293.0
TH1_k127_5232745_1 response regulator K02667 - - 0.000000000000000000000000000000000000002179 151.0
TH1_k127_5233217_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 557.0
TH1_k127_5233217_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 359.0
TH1_k127_5307313_0 PFAM peptidase K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 416.0
TH1_k127_5307313_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000002138 230.0
TH1_k127_5307313_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000009809 200.0
TH1_k127_5307313_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000007779 66.0
TH1_k127_5338312_0 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 396.0
TH1_k127_5338312_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000005298 219.0
TH1_k127_5338312_2 Oxidoreductase NAD-binding domain K02823 - - 0.000000000000000000000000000000000000000000000003643 183.0
TH1_k127_5338312_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000002057 49.0
TH1_k127_5351757_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 293.0
TH1_k127_5351757_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000169 271.0
TH1_k127_5352275_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000328 245.0
TH1_k127_5352275_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0001267 49.0
TH1_k127_5362513_0 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 381.0
TH1_k127_5362513_1 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 365.0
TH1_k127_5362513_2 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000002349 228.0
TH1_k127_5362513_3 Rnf-Nqr subunit, membrane protein K03613 - - 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
TH1_k127_5362513_4 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000004796 110.0
TH1_k127_537950_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 526.0
TH1_k127_537950_1 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 311.0
TH1_k127_537950_2 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000001215 204.0
TH1_k127_537950_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000001284 71.0
TH1_k127_5394568_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.145e-211 670.0
TH1_k127_5394568_1 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 350.0
TH1_k127_5394568_2 regulation of microtubule-based process K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.000000003358 58.0
TH1_k127_5405804_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 453.0
TH1_k127_5405804_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 354.0
TH1_k127_5405804_2 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000167 75.0
TH1_k127_5424260_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 455.0
TH1_k127_5424260_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001196 283.0
TH1_k127_5424260_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000003689 118.0
TH1_k127_5428246_0 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000002211 196.0
TH1_k127_5428246_1 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000006983 157.0
TH1_k127_5428246_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000008231 152.0
TH1_k127_5428246_3 Acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000001003 119.0
TH1_k127_5428680_0 cation transport ATPase K17686 - 3.6.3.54 1.422e-201 636.0
TH1_k127_5428680_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000006449 205.0
TH1_k127_5434591_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 493.0
TH1_k127_5434591_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 377.0
TH1_k127_5434591_2 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 327.0
TH1_k127_5434591_3 Proteasome subunit K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001174 263.0
TH1_k127_5436973_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336,K05299 - 1.17.1.10,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 489.0
TH1_k127_5436973_1 (Rhomboid) family K07059 - - 0.000000000000000000000000000000000000000000000000000000001942 205.0
TH1_k127_546806_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.798e-238 747.0
TH1_k127_546806_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000128 61.0
TH1_k127_5517557_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 525.0
TH1_k127_5517557_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 426.0
TH1_k127_5517557_10 Phospholipid methyltransferase - - - 0.00000000000000000006341 98.0
TH1_k127_5517557_11 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.000000000000000003311 91.0
TH1_k127_5517557_12 NosL - - - 0.00000000006084 70.0
TH1_k127_5517557_15 membrane K07058 - - 0.000000001959 69.0
TH1_k127_5517557_16 response to heat - - - 0.00002735 50.0
TH1_k127_5517557_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000111 268.0
TH1_k127_5517557_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
TH1_k127_5517557_4 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001716 266.0
TH1_k127_5517557_5 Sensor histidine kinase, HAMP domain-containing K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001481 257.0
TH1_k127_5517557_6 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000001194 202.0
TH1_k127_5517557_7 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.000000000000000000000000000000000000000000000000005005 190.0
TH1_k127_5517557_8 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000003057 157.0
TH1_k127_5517557_9 ABC-type Mn2 Zn2 transport system, permease component K09816,K09819,K19976 - - 0.0000000000000000000000000001336 121.0
TH1_k127_5527778_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1205.0
TH1_k127_5550886_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 508.0
TH1_k127_5550886_1 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 380.0
TH1_k127_5550886_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 360.0
TH1_k127_5550886_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 332.0
TH1_k127_5550886_4 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000005263 230.0
TH1_k127_5550886_5 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000001062 206.0
TH1_k127_5550886_6 Chemotaxis phosphatase CheX - - - 0.00000000000000000000000000000000000000000000000000003763 198.0
TH1_k127_5550886_7 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000002057 147.0
TH1_k127_5559112_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 396.0
TH1_k127_5559112_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000005093 166.0
TH1_k127_5559112_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000004803 110.0
TH1_k127_56199_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 468.0
TH1_k127_56199_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000001431 136.0
TH1_k127_5684851_0 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 486.0
TH1_k127_5684851_1 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 398.0
TH1_k127_5684851_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 348.0
TH1_k127_5684851_3 Hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001117 250.0
TH1_k127_5684851_4 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008789 243.0
TH1_k127_5687600_0 photoreceptor activity K03413,K07684,K07689 - - 0.000000000000000000000000000000000000002556 159.0
TH1_k127_5687600_1 - - - - 0.00002464 52.0
TH1_k127_5708498_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 407.0
TH1_k127_5708498_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002468 250.0
TH1_k127_5708498_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000001342 255.0
TH1_k127_5721076_0 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 291.0
TH1_k127_5721076_1 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000052 286.0
TH1_k127_5721076_2 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008953 274.0
TH1_k127_5721076_3 PBP superfamily domain K05772 - - 0.000000000000000006538 83.0
TH1_k127_5721076_4 Glycine-zipper domain - - - 0.0000000000000000399 85.0
TH1_k127_5721076_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000001853 73.0
TH1_k127_5740583_0 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000001676 137.0
TH1_k127_5740583_1 Methyltransferase MtaA K14080 - 2.1.1.246 0.0000000000000000000000000000002381 132.0
TH1_k127_5740583_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000002591 88.0
TH1_k127_5777357_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 495.0
TH1_k127_5777357_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 466.0
TH1_k127_5777357_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000004625 165.0
TH1_k127_5777357_3 - - - - 0.000000000000000000001128 101.0
TH1_k127_5815179_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 473.0
TH1_k127_5815179_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001713 267.0
TH1_k127_5815179_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000008401 177.0
TH1_k127_5815179_3 transcriptional regulator K03892 - - 0.0000000000001589 76.0
TH1_k127_5815179_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000346 61.0
TH1_k127_5886183_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 9.104e-195 614.0
TH1_k127_5886183_1 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000004394 206.0
TH1_k127_5886183_2 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000000000002903 129.0
TH1_k127_5886183_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000001855 104.0
TH1_k127_5928498_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.107e-231 733.0
TH1_k127_5933246_0 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 608.0
TH1_k127_5933246_1 - - - - 0.00000000000000000000000001474 113.0
TH1_k127_5933246_2 - - - - 0.000000005786 59.0
TH1_k127_5968186_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1330.0
TH1_k127_5968186_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1069.0
TH1_k127_5968186_2 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000005143 194.0
TH1_k127_5968186_4 response regulator - - - 0.00000000000000000000000000000000003577 147.0
TH1_k127_5968186_5 quinolinate catabolic process K00278,K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 0.000000000000000001136 88.0
TH1_k127_5981288_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 363.0
TH1_k127_5981288_1 von Willebrand factor (vWF) type A domain K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 302.0
TH1_k127_5981288_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000003127 216.0
TH1_k127_5981288_3 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000005296 147.0
TH1_k127_5993543_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.887e-292 905.0
TH1_k127_5993543_1 Dehydratase family K01687 - 4.2.1.9 1.692e-254 795.0
TH1_k127_5993543_2 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001632 256.0
TH1_k127_5993543_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000004228 224.0
TH1_k127_5993543_4 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000003656 209.0
TH1_k127_5993543_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000002157 198.0
TH1_k127_5993543_6 - - - - 0.0000000000000000000003934 100.0
TH1_k127_5993543_7 Protein of unknown function (DUF465) K09794 - - 0.000000000000000004221 86.0
TH1_k127_5993543_8 - - - - 0.000000003542 58.0
TH1_k127_6014483_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 521.0
TH1_k127_6014483_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 437.0
TH1_k127_6014483_2 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000538 258.0
TH1_k127_6026167_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 304.0
TH1_k127_6026167_1 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000048 225.0
TH1_k127_6026167_3 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000009291 128.0
TH1_k127_6026167_4 bacterial (prokaryotic) histone like domain K04764 - - 0.000000000000000000000000000005737 121.0
TH1_k127_6026167_6 protein secretion K03116,K03117 - - 0.00000000000004102 76.0
TH1_k127_6055228_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 603.0
TH1_k127_6055228_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 595.0
TH1_k127_6055228_10 - - - - 0.000000000000000000000000000000000000000001394 165.0
TH1_k127_6055228_11 photosynthesis - - - 0.00000000000000000000000000000000000002339 150.0
TH1_k127_6055228_12 - - - - 0.000000000000000000000000000000004112 132.0
TH1_k127_6055228_13 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000001133 136.0
TH1_k127_6055228_14 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000000000000002253 127.0
TH1_k127_6055228_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000001628 92.0
TH1_k127_6055228_16 Transcriptional regulator K02529 - - 0.000000000000000005331 91.0
TH1_k127_6055228_2 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 551.0
TH1_k127_6055228_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 320.0
TH1_k127_6055228_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 320.0
TH1_k127_6055228_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003257 270.0
TH1_k127_6055228_6 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000001884 232.0
TH1_k127_6055228_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000001387 197.0
TH1_k127_6055228_8 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000003727 173.0
TH1_k127_6055228_9 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001137 167.0
TH1_k127_6071242_0 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 449.0
TH1_k127_6071242_1 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000006709 147.0
TH1_k127_6071242_2 peptidyl-tyrosine sulfation - - - 0.000000000002519 76.0
TH1_k127_6077799_0 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 351.0
TH1_k127_6077799_1 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000002222 115.0
TH1_k127_6077799_2 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000002733 112.0
TH1_k127_6077799_3 Pilus assembly protein, PilP K02665 - - 0.000000001512 66.0
TH1_k127_6077799_4 PFAM type II and III secretion system protein K02666 - - 0.0003295 51.0
TH1_k127_6080273_0 DNA polymerase K02347 - - 7.258e-226 713.0
TH1_k127_6080273_1 PFAM Type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 325.0
TH1_k127_6080273_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 295.0
TH1_k127_6089741_0 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 357.0
TH1_k127_6089741_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000161 272.0
TH1_k127_6089741_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000001342 168.0
TH1_k127_6089741_3 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000009025 151.0
TH1_k127_6089741_4 Domain of unknown function (DUF4160) - - - 0.00000000000000000000002128 101.0
TH1_k127_6089741_7 Protein of unknown function (DUF2442) - - - 0.000000000000000888 81.0
TH1_k127_6110684_0 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 504.0
TH1_k127_6110684_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001234 283.0
TH1_k127_6110684_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000001191 243.0
TH1_k127_6110684_3 - - - - 0.000000000000000000000000001307 119.0
TH1_k127_6110684_4 Mo-molybdopterin cofactor metabolic process - - - 0.00000000005991 66.0
TH1_k127_6143667_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 6.678e-210 657.0
TH1_k127_6143667_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 392.0
TH1_k127_6143667_2 Male sterility protein K00091 - 1.1.1.219 0.00000001472 59.0
TH1_k127_6143667_3 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0001415 48.0
TH1_k127_6249261_0 Telomere recombination K04656 - - 1.057e-215 689.0
TH1_k127_6249261_1 Hydrogenase formation hypA family K04654 - - 0.000008339 49.0
TH1_k127_6273911_0 CHAT domain - - - 1.79e-319 1022.0
TH1_k127_6289586_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 607.0
TH1_k127_6289586_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity K03182 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 358.0
TH1_k127_6289586_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008894 271.0
TH1_k127_6289586_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000002594 253.0
TH1_k127_6289586_4 nitric oxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002315 216.0
TH1_k127_6315672_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 576.0
TH1_k127_6315672_1 phosphorelay sensor kinase activity K03320,K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002911 279.0
TH1_k127_6315672_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000002149 196.0
TH1_k127_6315672_3 - - - - 0.0000000000000000000000001156 109.0
TH1_k127_6315672_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000004633 105.0
TH1_k127_6316702_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 405.0
TH1_k127_6364287_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 521.0
TH1_k127_6364287_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 497.0
TH1_k127_6364287_2 4Fe-4S double cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 351.0
TH1_k127_6364287_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 333.0
TH1_k127_6364287_4 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000001365 113.0
TH1_k127_6364287_5 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000001359 108.0
TH1_k127_6364287_6 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000001667 112.0
TH1_k127_6374634_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1012.0
TH1_k127_6374634_1 HlyD membrane-fusion protein of T1SS K07798 - - 0.00000000001548 65.0
TH1_k127_6381882_0 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 456.0
TH1_k127_6381882_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 426.0
TH1_k127_6381882_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 407.0
TH1_k127_6381882_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002898 278.0
TH1_k127_6381882_4 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003002 287.0
TH1_k127_6381882_5 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000001328 167.0
TH1_k127_6381882_6 Alginate export - - - 0.000000000000000000000000000000003709 133.0
TH1_k127_6381882_7 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000000000000000000001832 100.0
TH1_k127_6381882_8 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000004866 90.0
TH1_k127_6383823_0 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 410.0
TH1_k127_6383823_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006122 277.0
TH1_k127_6383823_2 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000004295 186.0
TH1_k127_6383823_3 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000003604 128.0
TH1_k127_6383823_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000002542 114.0
TH1_k127_6383823_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000004093 109.0
TH1_k127_6383823_6 4Fe-4S single cluster domain - - - 0.000000000000000001517 97.0
TH1_k127_6383823_7 Iron-sulfur cluster-binding domain - - - 0.0000000000000026 88.0
TH1_k127_6383823_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000186 60.0
TH1_k127_6394471_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000002861 232.0
TH1_k127_6394471_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000005882 153.0
TH1_k127_6394471_2 viral genome integration into host DNA K04763 - - 0.000000000000000000000000000001736 120.0
TH1_k127_6394471_3 COG3344 Retron-type reverse transcriptase - - - 0.000000000000000001296 87.0
TH1_k127_6400612_0 PFAM type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 496.0
TH1_k127_6400612_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 482.0
TH1_k127_6400612_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000002013 207.0
TH1_k127_6400612_3 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.00000000000000000000000004252 111.0
TH1_k127_6400612_4 Modulates RecA activity K03565 - - 0.0000007935 58.0
TH1_k127_6428051_0 cytochrome c biogenesis protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 387.0
TH1_k127_6428051_1 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000002072 177.0
TH1_k127_6428051_2 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000002423 58.0
TH1_k127_6459395_0 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000003243 217.0
TH1_k127_6459395_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000002462 126.0
TH1_k127_6459395_2 NAD(P)H-binding - - - 0.000000539 59.0
TH1_k127_6474985_0 Tetratricopeptide repeat - - - 0.00000000000000000000000009205 111.0
TH1_k127_6474985_1 DnaJ molecular chaperone homology domain K05516 - - 0.00000000001602 77.0
TH1_k127_6490862_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 424.0
TH1_k127_6490862_1 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 307.0
TH1_k127_6490862_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001055 282.0
TH1_k127_6490862_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006178 259.0
TH1_k127_6490862_4 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000004653 113.0
TH1_k127_6490862_5 - - - - 0.00000000000000000000000004456 112.0
TH1_k127_6490862_6 Protein of unknown function (DUF1622) - - - 0.00000000000000000000001203 104.0
TH1_k127_64915_0 type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 570.0
TH1_k127_64915_1 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 490.0
TH1_k127_64915_2 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 366.0
TH1_k127_64915_3 PFAM Glycosyl transferase family 2 K12992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 312.0
TH1_k127_64915_4 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000002048 86.0
TH1_k127_64915_5 pilus assembly protein PilW K02459,K02672 - - 0.000000007903 65.0
TH1_k127_64915_6 General Secretion Pathway protein K02457 - - 0.0000007311 57.0
TH1_k127_64915_7 overlaps another CDS with the same product name K02458 - - 0.000001054 56.0
TH1_k127_6571627_0 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000001056 218.0
TH1_k127_6571627_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000002183 202.0
TH1_k127_6571627_2 Belongs to the Nudix hydrolase family - - - 0.000000000000000000001839 96.0
TH1_k127_6571627_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000001698 91.0
TH1_k127_6571627_4 Belongs to the Nudix hydrolase family - - - 0.00003401 48.0
TH1_k127_6599482_0 GAF domain - - - 1.434e-209 672.0
TH1_k127_6599482_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000001525 165.0
TH1_k127_6599482_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00002208 49.0
TH1_k127_6601593_0 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.000000000000000000000000000000000000000000000000000214 190.0
TH1_k127_6601593_2 - - - - 0.00000001664 65.0
TH1_k127_6601593_4 COG3156 Type II secretory pathway, component PulK K02460 - - 0.000006541 53.0
TH1_k127_6605513_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 2.869e-230 726.0
TH1_k127_6605513_1 SMART Elongator protein 3 MiaB NifB - - - 1.871e-207 657.0
TH1_k127_6605513_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 527.0
TH1_k127_6605513_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 515.0
TH1_k127_6605513_4 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 273.0
TH1_k127_6605513_5 Protoporphyrinogen oxidase - - - 0.000000000000000000000000000000000000000009528 160.0
TH1_k127_6605513_6 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000000000000000000002808 158.0
TH1_k127_6605513_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000002056 130.0
TH1_k127_6605513_8 hydrogenase maturation protease K03605 - - 0.00000000000000000000002812 108.0
TH1_k127_6605513_9 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.00000000000000000009652 93.0
TH1_k127_6618423_0 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 328.0
TH1_k127_6618423_1 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000000000003157 205.0
TH1_k127_6618423_2 electron transfer activity K02305,K08738 - - 0.000000000000000000000000000000000000000000000000000001168 197.0
TH1_k127_6618423_3 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000002555 95.0
TH1_k127_664039_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.059e-240 752.0
TH1_k127_664039_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 428.0
TH1_k127_664039_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 373.0
TH1_k127_664039_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 321.0
TH1_k127_664039_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000002539 141.0
TH1_k127_664039_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000001096 127.0
TH1_k127_6651315_0 Peptidase family M28 - - - 0.0 1024.0
TH1_k127_6651315_1 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 455.0
TH1_k127_6651315_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 401.0
TH1_k127_6651315_3 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000003491 199.0
TH1_k127_6651315_4 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000001086 127.0
TH1_k127_6651315_5 - - - - 0.000000000000000000001336 99.0
TH1_k127_6754600_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 7.766e-258 814.0
TH1_k127_6754600_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 524.0
TH1_k127_6754600_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 408.0
TH1_k127_6754600_3 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 361.0
TH1_k127_6754600_4 Thiamine biosynthesis protein (ThiI) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 307.0
TH1_k127_6754600_5 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000006751 228.0
TH1_k127_6754600_6 Transcriptional regulator, MerR family - - - 0.000000000000000000000000000000000008741 141.0
TH1_k127_6754600_7 Tetratricopeptide repeat protein - - - 0.0002532 48.0
TH1_k127_6771273_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 482.0
TH1_k127_6771273_1 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000000004509 200.0
TH1_k127_6771273_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.000000000000000000000282 103.0
TH1_k127_6774155_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1014.0
TH1_k127_6774155_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 536.0
TH1_k127_6774155_2 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 410.0
TH1_k127_6774155_3 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 347.0
TH1_k127_6774155_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 336.0
TH1_k127_6774155_5 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.0000000000000000000000143 104.0
TH1_k127_6774155_7 PFAM Sulfotransferase domain - - - 0.0001409 46.0
TH1_k127_6797782_0 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004874 256.0
TH1_k127_6797782_1 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000005749 102.0
TH1_k127_6797782_2 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000002993 67.0
TH1_k127_6822214_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 514.0
TH1_k127_6822214_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 484.0
TH1_k127_6822214_10 PFAM CheW-like domain K03408 - - 0.00007475 49.0
TH1_k127_6822214_2 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 291.0
TH1_k127_6822214_3 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
TH1_k127_6822214_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000008808 255.0
TH1_k127_6822214_5 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000009485 160.0
TH1_k127_6822214_6 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000001711 139.0
TH1_k127_6822214_7 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000003979 145.0
TH1_k127_6822214_8 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000006756 61.0
TH1_k127_6822214_9 Oxidoreductase - - - 0.0000001917 56.0
TH1_k127_6829337_0 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 323.0
TH1_k127_6829337_1 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000000002715 183.0
TH1_k127_6829337_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000004079 186.0
TH1_k127_6829337_3 Thioredoxin-like K02199 - - 0.0000000000000000000000000000000001862 138.0
TH1_k127_6829337_4 cheY-homologous receiver domain - - - 0.00009741 54.0
TH1_k127_6869196_0 Bacterial protein of unknown function (DUF853) K06915 - - 9.631e-222 696.0
TH1_k127_6869196_1 histidine kinase A domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 480.0
TH1_k127_6869196_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008437 276.0
TH1_k127_6869196_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003924 274.0
TH1_k127_6869196_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000288 258.0
TH1_k127_6869196_5 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000605 140.0
TH1_k127_6901003_0 Surface antigen K07277 - - 2.872e-247 784.0
TH1_k127_6901003_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.073e-222 702.0
TH1_k127_6901003_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 383.0
TH1_k127_6901003_3 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 394.0
TH1_k127_6901003_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 375.0
TH1_k127_6901003_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 328.0
TH1_k127_6901003_6 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000574 261.0
TH1_k127_6901003_7 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000004485 202.0
TH1_k127_6901003_8 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000000000002151 152.0
TH1_k127_6901003_9 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00000000000000000001015 99.0
TH1_k127_6904320_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1135.0
TH1_k127_6904320_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.036e-235 730.0
TH1_k127_6904320_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000006368 146.0
TH1_k127_6904320_11 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000009017 145.0
TH1_k127_6904320_12 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.00000000000000000000000000001333 129.0
TH1_k127_6904320_14 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000002522 85.0
TH1_k127_6904320_15 structural constituent of ribosome K02913 - - 0.0000000000000004765 78.0
TH1_k127_6904320_16 4Fe-4S ferredoxin iron-sulfur binding domain protein K05337 - - 0.00000000000006329 73.0
TH1_k127_6904320_17 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000001078 66.0
TH1_k127_6904320_18 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000008507 51.0
TH1_k127_6904320_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 370.0
TH1_k127_6904320_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 340.0
TH1_k127_6904320_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000686 272.0
TH1_k127_6904320_5 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001403 269.0
TH1_k127_6904320_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000004163 251.0
TH1_k127_6904320_7 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000004124 244.0
TH1_k127_6904320_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000001057 217.0
TH1_k127_6904320_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000001695 215.0
TH1_k127_6906598_0 PFAM Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 428.0
TH1_k127_6906598_1 Type I restriction-modification system methyltransferase subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 342.0
TH1_k127_6906598_2 TaqI-like C-terminal specificity domain - - - 0.00000000000000000000000000002516 124.0
TH1_k127_6906598_3 Universal stress protein family - - - 0.00000000003129 70.0
TH1_k127_6906598_4 Universal stress protein K06149 - - 0.0000000001696 69.0
TH1_k127_6906598_5 PFAM UspA domain protein - - - 0.0001277 49.0
TH1_k127_692232_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 412.0
TH1_k127_692232_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 297.0
TH1_k127_692232_2 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004523 265.0
TH1_k127_692232_3 Radical SAM - - - 0.000000000000000000000000000000000008382 150.0
TH1_k127_692232_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000001634 147.0
TH1_k127_692232_5 transferase activity, transferring amino-acyl groups - - - 0.000000000000000000000000000000002705 143.0
TH1_k127_692232_6 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000000212 123.0
TH1_k127_692232_7 FemAB family - - - 0.000000000008816 77.0
TH1_k127_692232_8 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00001841 53.0
TH1_k127_692232_9 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00001898 56.0
TH1_k127_7000254_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1147.0
TH1_k127_7000254_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 4.883e-313 970.0
TH1_k127_7000254_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 503.0
TH1_k127_7000254_3 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005659 262.0
TH1_k127_7000254_4 Putative regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000001665 204.0
TH1_k127_7000254_5 PFAM Glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000002564 164.0
TH1_k127_7058375_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 5.338e-209 662.0
TH1_k127_7058375_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 603.0
TH1_k127_7058375_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001528 287.0
TH1_k127_7058375_3 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001121 248.0
TH1_k127_7058375_4 metallopeptidase activity K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002117 245.0
TH1_k127_7058375_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003842 243.0
TH1_k127_7058375_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000009997 199.0
TH1_k127_7058375_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000006697 148.0
TH1_k127_7082348_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.299e-205 647.0
TH1_k127_7082348_1 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 469.0
TH1_k127_7082348_2 NOG31153 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008279 256.0
TH1_k127_7082348_4 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000259 121.0
TH1_k127_7082348_5 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000001177 80.0
TH1_k127_7082348_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000003559 61.0
TH1_k127_7104831_0 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 375.0
TH1_k127_7104831_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 313.0
TH1_k127_7104831_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000003563 132.0
TH1_k127_7104831_3 electron transfer activity K05337,K17247 - - 0.0000000000000000000000000001639 117.0
TH1_k127_7104831_4 Cupin 2, conserved barrel domain protein - - - 0.000000000006395 70.0
TH1_k127_7157940_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 565.0
TH1_k127_7157940_1 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 448.0
TH1_k127_7157940_2 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 413.0
TH1_k127_7157940_3 Citrate synthase, C-terminal domain K01647,K01659 - 2.3.3.1,2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 401.0
TH1_k127_7157940_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 391.0
TH1_k127_7157940_5 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 313.0
TH1_k127_7157940_6 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000009626 143.0
TH1_k127_7157940_7 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000002898 106.0
TH1_k127_7188163_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 297.0
TH1_k127_7188163_1 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000006628 228.0
TH1_k127_7188163_2 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000007101 179.0
TH1_k127_7188163_3 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000005435 88.0
TH1_k127_7199971_0 Amine oxidase, flavin-containing - - - 0.00000000000000000000000000000000000000000000000000000001926 207.0
TH1_k127_7199971_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000107 57.0
TH1_k127_7207078_0 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 472.0
TH1_k127_721688_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.028e-275 859.0
TH1_k127_721688_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 531.0
TH1_k127_721688_2 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 489.0
TH1_k127_721688_3 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 334.0
TH1_k127_721688_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000001734 204.0
TH1_k127_721688_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000002995 199.0
TH1_k127_721688_6 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000005072 167.0
TH1_k127_721688_7 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000002416 109.0
TH1_k127_7277754_0 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 327.0
TH1_k127_7277754_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000007471 153.0
TH1_k127_7277754_2 AMP binding - - - 0.000000000000000000000000000000000000004042 156.0
TH1_k127_7277754_3 Thiamine-binding protein - - - 0.000000000000000000000000000000007194 131.0
TH1_k127_7277754_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000004559 124.0
TH1_k127_729117_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1317.0
TH1_k127_729117_1 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 550.0
TH1_k127_729117_2 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002053 276.0
TH1_k127_729117_3 - - - - 0.00000000000000006846 87.0
TH1_k127_729117_4 peptidoglycan turnover K00966,K00973,K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221,2.7.7.13,2.7.7.24 0.00001053 49.0
TH1_k127_729117_5 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0006531 44.0
TH1_k127_7307283_0 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003266 265.0
TH1_k127_7307283_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 254.0
TH1_k127_7307283_2 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000006318 227.0
TH1_k127_7307283_3 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000006941 230.0
TH1_k127_7307283_4 protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000006765 150.0
TH1_k127_7307283_5 MazG nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000000003096 134.0
TH1_k127_7307283_6 regulation of translation K03530 - - 0.000000000000000000000000000000001958 131.0
TH1_k127_7307283_7 Protein of unknown function (DUF3141) - - - 0.0000000000000000000000000002069 119.0
TH1_k127_7312351_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 508.0
TH1_k127_7312351_1 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003093 267.0
TH1_k127_7312351_2 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000001265 235.0
TH1_k127_7312969_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.07e-200 645.0
TH1_k127_7312969_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 443.0
TH1_k127_7312969_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000001602 246.0
TH1_k127_7312969_3 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000001774 215.0
TH1_k127_7312969_4 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000001408 223.0
TH1_k127_7312969_5 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.000000000000000000000000000000000000002986 151.0
TH1_k127_7312969_6 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000002393 129.0
TH1_k127_7312969_7 Domain of unknown function (DUF1858) - - - 0.00000000000000000001024 94.0
TH1_k127_7312969_9 - - - - 0.00004682 47.0
TH1_k127_7377345_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 497.0
TH1_k127_7377345_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000001078 229.0
TH1_k127_7377345_2 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000000000000004414 211.0
TH1_k127_7377345_3 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000632 168.0
TH1_k127_7377345_4 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000006036 158.0
TH1_k127_7377345_5 - - - - 0.0000000000002549 72.0
TH1_k127_7377345_6 carbon dioxide binding K04653,K04654 - - 0.000007896 51.0
TH1_k127_7377821_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 399.0
TH1_k127_7377821_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 324.0
TH1_k127_7377821_2 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000004125 230.0
TH1_k127_7377821_3 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000001127 157.0
TH1_k127_7377821_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001441 134.0
TH1_k127_7377821_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000002158 100.0
TH1_k127_7377821_6 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000005825 64.0
TH1_k127_7377821_7 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0006651 42.0
TH1_k127_7385619_0 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 394.0
TH1_k127_7385619_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000002933 243.0
TH1_k127_7385619_2 Transcription termination factor nusG - - - 0.000000000000000000000000000000000000000000000000000000000000004591 221.0
TH1_k127_7385619_3 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.000000000000000000000000000000000000000000000000000001314 207.0
TH1_k127_7385619_4 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000001267 188.0
TH1_k127_7385619_5 acr, cog1430 K09005 - - 0.00000226 61.0
TH1_k127_7396229_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 6.642e-269 853.0
TH1_k127_7436525_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 597.0
TH1_k127_7436525_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 527.0
TH1_k127_7436525_2 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 465.0
TH1_k127_7436525_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 405.0
TH1_k127_7436525_4 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 395.0
TH1_k127_7436525_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 359.0
TH1_k127_7436525_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 338.0
TH1_k127_7436525_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 319.0
TH1_k127_7436525_8 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000005654 265.0
TH1_k127_7436525_9 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000001098 195.0
TH1_k127_7459782_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001967 295.0
TH1_k127_7459782_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000001534 143.0
TH1_k127_7470317_0 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 488.0
TH1_k127_7481181_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000006645 205.0
TH1_k127_7481181_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000004723 136.0
TH1_k127_7481181_2 Radical SAM superfamily K03639 - 4.1.99.22 0.00000000000000000003776 102.0
TH1_k127_7481181_3 coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000005508 91.0
TH1_k127_7491377_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001215 278.0
TH1_k127_7491377_1 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001065 275.0
TH1_k127_7491377_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000005323 216.0
TH1_k127_7491377_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000006949 186.0
TH1_k127_7522270_0 (ABC) transporter K02028,K02029,K09972,K10004,K10010 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000001637 191.0
TH1_k127_7522270_1 Belongs to the MurCDEF family - - - 0.000000000000000000000000000000000000000000000005694 182.0
TH1_k127_7590230_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002883 289.0
TH1_k127_7590230_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000009886 217.0
TH1_k127_7590230_2 glycosyl transferase group 1 K00640,K18687 - 2.3.1.30,6.2.1.41 0.00000000000295 69.0
TH1_k127_7593709_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 506.0
TH1_k127_7593709_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 402.0
TH1_k127_7593709_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000003712 233.0
TH1_k127_764355_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K11384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 295.0
TH1_k127_764355_1 homolog subfamily A member K09504 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000001813 70.0
TH1_k127_764355_2 Bacterial regulatory protein, Fis family K15012 - - 0.0000007764 55.0
TH1_k127_7668288_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 414.0
TH1_k127_7668288_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 313.0
TH1_k127_7668288_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000004715 259.0
TH1_k127_7668288_3 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000002337 239.0
TH1_k127_7668288_4 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000007947 190.0
TH1_k127_7668288_5 cAMP biosynthetic process - - - 0.00000002456 67.0
TH1_k127_7684160_0 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 9.758e-298 930.0
TH1_k127_7684160_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001429 284.0
TH1_k127_7684160_2 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000002542 145.0
TH1_k127_7684160_3 - - - - 0.000000000000000000000000000000000002312 142.0
TH1_k127_7703703_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000002688 196.0
TH1_k127_7703703_1 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000008432 100.0
TH1_k127_7703703_2 - - - - 0.00000000000000657 81.0
TH1_k127_7717226_0 - - - - 0.00000000000000000000000000000000000002346 147.0
TH1_k127_7717226_1 Phospholipid methyltransferase - - - 0.00000000000000001923 90.0
TH1_k127_7717226_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000001171 61.0
TH1_k127_7717226_3 Secretin and TonB N terminus short domain K02666 - - 0.0001288 50.0
TH1_k127_7730380_0 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 424.0
TH1_k127_7730380_1 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 371.0
TH1_k127_7730380_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 320.0
TH1_k127_7730380_3 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001373 207.0
TH1_k127_7730380_4 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0003641 43.0
TH1_k127_7752789_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 480.0
TH1_k127_7752789_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004624 249.0
TH1_k127_7752789_2 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002184 234.0
TH1_k127_7752789_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000002421 129.0
TH1_k127_7752789_4 Peptidase, M23 - - - 0.00002655 53.0
TH1_k127_7753763_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 357.0
TH1_k127_7753763_1 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000003825 136.0
TH1_k127_7753763_2 SMART Cold shock protein K03704 - - 0.0000000000000000000000000007605 113.0
TH1_k127_7791167_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 393.0
TH1_k127_7791167_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000002465 178.0
TH1_k127_7791167_2 Roadblock/LC7 domain - - - 0.00000000000000000002643 96.0
TH1_k127_7791167_3 Tetratricopeptide repeat - - - 0.0000000000000001322 92.0
TH1_k127_7791167_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000001123 74.0
TH1_k127_7826471_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001425 298.0
TH1_k127_7826471_1 ferredoxin-thioredoxin reductase activity - - - 0.00000000000000000000000000000000006335 134.0
TH1_k127_7826471_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.0000000000000000000002 100.0
TH1_k127_7826471_4 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.00000002236 67.0
TH1_k127_7826471_5 Belongs to the PEP-utilizing enzyme family K08483,K08484 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 0.000001099 61.0
TH1_k127_7826471_6 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000606 50.0
TH1_k127_783357_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 8.948e-312 964.0
TH1_k127_783357_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 455.0
TH1_k127_783357_2 SMART Cold shock protein K03704 - - 0.000000000000000000000000000002636 120.0
TH1_k127_783357_3 Stringent starvation protein B K09985 - - 0.00000000000000000000000000009002 121.0
TH1_k127_7873006_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 2.357e-222 702.0
TH1_k127_7873006_1 Threonyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000001218 165.0
TH1_k127_7873006_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000006671 127.0
TH1_k127_7873006_3 heme oxygenase (decyclizing) activity - - - 0.0000000000000000005432 90.0
TH1_k127_7905313_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 583.0
TH1_k127_7905313_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 301.0
TH1_k127_7905313_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000001716 109.0
TH1_k127_7905313_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000008594 88.0
TH1_k127_792111_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 485.0
TH1_k127_792111_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 469.0
TH1_k127_792111_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000006793 269.0
TH1_k127_792111_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000001885 245.0
TH1_k127_792111_4 DivIVA protein K04074 - - 0.000000000000000000000000000000000000000000000000000000000000000001893 229.0
TH1_k127_792111_5 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000135 209.0
TH1_k127_792111_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000001248 159.0
TH1_k127_792111_7 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000000000000000000000000000000000005769 141.0
TH1_k127_792111_8 YGGT family K02221 - - 0.0000000000000000000000000000000000296 137.0
TH1_k127_7997336_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 369.0
TH1_k127_7997336_1 PFAM membrane protein of K08972 - - 0.00000000000000000000000000867 113.0
TH1_k127_7997336_2 AsmA-like C-terminal region K07289 - - 0.0000000001035 67.0
TH1_k127_8036752_0 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.00000000000000000003806 100.0
TH1_k127_8036752_1 Glycosyltransferase like family 2 - - - 0.000000000000000001566 86.0
TH1_k127_8036752_2 oligosaccharyl transferase activity - - - 0.00000000000000000179 100.0
TH1_k127_8036752_4 Tetratricopeptide repeat - - - 0.00009674 55.0
TH1_k127_8059130_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1096.0
TH1_k127_8059130_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 432.0
TH1_k127_8059130_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 321.0
TH1_k127_8059130_3 helix_turn_helix gluconate operon transcriptional repressor K03710 - - 0.000000000000000007995 88.0
TH1_k127_8059130_4 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000003245 57.0
TH1_k127_8084353_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.769e-298 920.0
TH1_k127_8084353_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000007601 89.0
TH1_k127_8103420_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 555.0
TH1_k127_8103420_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 296.0
TH1_k127_8103420_2 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000001169 201.0
TH1_k127_8103420_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000005686 172.0
TH1_k127_8109631_0 3'-5' exonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000007761 194.0
TH1_k127_8109631_1 ATPase involved in DNA repair - - - 0.000000000000000000000000000000000000000002758 168.0
TH1_k127_8132830_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 5.09e-201 633.0
TH1_k127_8132830_1 transferase activity, transferring glycosyl groups K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 320.0
TH1_k127_8132830_2 biosynthesis glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 308.0
TH1_k127_8132830_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000007358 248.0
TH1_k127_8132830_4 YbbR-like protein - - - 0.00000000000000000000000000000000000000000002439 169.0
TH1_k127_8132830_5 methyltransferase - - - 0.00000000000000000000000000000000001749 144.0
TH1_k127_8132830_6 Spore maturation protein cgeB K06320 - - 0.0000006516 51.0
TH1_k127_8132830_7 O-Antigen ligase - - - 0.000001574 60.0
TH1_k127_8163871_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 459.0
TH1_k127_8163871_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 325.0
TH1_k127_8163871_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001359 269.0
TH1_k127_8163871_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000483 174.0
TH1_k127_8163871_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000003452 155.0
TH1_k127_8163871_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000005011 152.0
TH1_k127_8163871_6 toxin-antitoxin pair type II binding - - - 0.00000002837 57.0
TH1_k127_8172675_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 524.0
TH1_k127_8172675_1 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 480.0
TH1_k127_8172675_2 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 336.0
TH1_k127_8172675_3 MgtC family K07507 - - 0.00000000000000000000000000000000000000007855 162.0
TH1_k127_8172675_4 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000009582 111.0
TH1_k127_8198714_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 511.0
TH1_k127_8198714_1 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008298 272.0
TH1_k127_8198714_2 Universal stress protein family K07090 - - 0.0000003592 53.0
TH1_k127_8237448_0 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 388.0
TH1_k127_8237448_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000003136 214.0
TH1_k127_825300_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 441.0
TH1_k127_825300_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 305.0
TH1_k127_825300_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000002852 219.0
TH1_k127_825300_3 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000003333 183.0
TH1_k127_825300_4 - - - - 0.000000000000000000000000000000000000000261 155.0
TH1_k127_825300_5 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000002831 101.0
TH1_k127_825300_6 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.000000000000000006946 84.0
TH1_k127_8258954_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 4.724e-226 707.0
TH1_k127_8258954_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 443.0
TH1_k127_8258954_2 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000002641 249.0
TH1_k127_8258954_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000813 244.0
TH1_k127_8258954_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000001989 175.0
TH1_k127_8308901_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 3.987e-220 697.0
TH1_k127_8308901_1 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 299.0
TH1_k127_8308901_2 PFAM peptidase M28 - - - 0.000000000000000000000000000000000000000000002929 171.0
TH1_k127_8403439_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 367.0
TH1_k127_8403439_1 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000001804 175.0
TH1_k127_8443461_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.056e-280 869.0
TH1_k127_8443461_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 591.0
TH1_k127_8443461_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 461.0
TH1_k127_8443461_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 338.0
TH1_k127_8443461_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 306.0
TH1_k127_8443461_5 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000004412 171.0
TH1_k127_8443461_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000365 136.0
TH1_k127_8443461_8 Rhomboid family - - - 0.0001028 45.0
TH1_k127_8466052_0 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 313.0
TH1_k127_8466052_1 YtxH-like protein - - - 0.000000000000000000000000000000009148 130.0
TH1_k127_8466052_2 Telomere recombination K04656 - - 0.0000000000000000000000003371 108.0
TH1_k127_8466052_4 nickel cation binding K04651,K19640 - - 0.00000000000000001977 87.0
TH1_k127_8466052_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000003427 54.0
TH1_k127_8492974_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 454.0
TH1_k127_8492974_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 368.0
TH1_k127_8492974_2 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 332.0
TH1_k127_8492974_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007344 244.0
TH1_k127_8492974_4 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000178 218.0
TH1_k127_8492974_5 carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000009164 121.0
TH1_k127_850406_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.904e-195 617.0
TH1_k127_850406_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 470.0
TH1_k127_850406_2 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 312.0
TH1_k127_850406_3 endonuclease III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005839 254.0
TH1_k127_850406_4 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000001721 238.0
TH1_k127_850406_5 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000000002374 143.0
TH1_k127_850406_6 Putative zinc-finger - - - 0.00000000000000000000000000001464 131.0
TH1_k127_850406_7 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000000000000000000002366 120.0
TH1_k127_850406_8 LysM domain - - - 0.00000000000000000000000000004199 129.0
TH1_k127_8532741_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 570.0
TH1_k127_8532741_1 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 364.0
TH1_k127_8532741_2 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000004428 128.0
TH1_k127_8532741_3 Sulfurtransferase TusA K04085 - - 0.00000000000000000006187 91.0
TH1_k127_8532741_4 NAD+ diphosphatase activity K01515,K03426 - 3.6.1.13,3.6.1.22 0.0000004957 57.0
TH1_k127_8532741_5 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0001533 51.0
TH1_k127_8543228_0 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 509.0
TH1_k127_8543228_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 396.0
TH1_k127_8543228_2 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 342.0
TH1_k127_8543228_3 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000001372 205.0
TH1_k127_8543228_4 heat shock protein binding K05516 - - 0.0002798 45.0
TH1_k127_8577949_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1860.0
TH1_k127_8577949_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000007536 74.0
TH1_k127_8579986_0 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001372 273.0
TH1_k127_8579986_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000005058 102.0
TH1_k127_8579986_2 Histidine kinase-like ATPase domain - - - 0.0000000000003999 71.0
TH1_k127_8580676_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 412.0
TH1_k127_8580676_1 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 389.0
TH1_k127_8580676_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000002999 244.0
TH1_k127_8580676_3 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000006349 165.0
TH1_k127_8580676_4 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000009681 151.0
TH1_k127_8602112_0 helicase K16899 - 3.6.4.12 0.000000000000000152 94.0
TH1_k127_8602305_0 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001124 242.0
TH1_k127_8602305_1 GAF domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000172 244.0
TH1_k127_8602305_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000622 220.0
TH1_k127_8627111_0 two-component system, chemotaxis family, sensor kinase CheA with response regulator domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000006181 259.0
TH1_k127_8627111_1 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000001077 189.0
TH1_k127_8627111_2 PFAM extracellular solute-binding protein family 1 K02040 - - 0.0000000000000000000000000000000000000000001678 169.0
TH1_k127_8627111_3 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000002711 153.0
TH1_k127_8661008_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 7.419e-310 957.0
TH1_k127_8661008_1 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 383.0
TH1_k127_8661008_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 337.0
TH1_k127_8661008_3 PFAM Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000234 213.0
TH1_k127_8669928_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 296.0
TH1_k127_8669928_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006094 258.0
TH1_k127_8669928_2 GYD domain - - - 0.000000000000000000000000000000000000005198 147.0
TH1_k127_8669928_3 Putative regulatory protein - - - 0.000001858 51.0
TH1_k127_8749757_0 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 425.0
TH1_k127_8749757_1 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 376.0
TH1_k127_8749757_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 321.0
TH1_k127_8749757_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000003041 67.0
TH1_k127_8756097_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 426.0
TH1_k127_8756097_1 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000009698 198.0
TH1_k127_8756097_2 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.000000000000000000000000000000000001648 141.0
TH1_k127_8764660_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1098.0
TH1_k127_8764660_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.007e-223 709.0
TH1_k127_8764660_2 Sodium/hydrogen exchanger family K03455,K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 390.0
TH1_k127_8764660_3 calcium, potassium:sodium antiporter activity K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 370.0
TH1_k127_877978_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 347.0
TH1_k127_877978_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001579 279.0
TH1_k127_877978_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003894 260.0
TH1_k127_877978_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000003724 230.0
TH1_k127_877978_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000004478 137.0
TH1_k127_8823465_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 487.0
TH1_k127_8823465_1 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 401.0
TH1_k127_8823465_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000001668 217.0
TH1_k127_8823465_3 - - - - 0.0000000000000000000000000001367 118.0
TH1_k127_8823465_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000002209 62.0
TH1_k127_8838505_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 478.0
TH1_k127_8838505_1 PHB de-polymerase C-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 455.0
TH1_k127_8838505_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000005951 216.0
TH1_k127_8838505_3 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000000000000004836 101.0
TH1_k127_8843734_0 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 345.0
TH1_k127_8843734_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000007278 165.0
TH1_k127_8843734_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000006363 112.0
TH1_k127_8864818_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1255.0
TH1_k127_8864818_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 282.0
TH1_k127_8864818_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001057 282.0
TH1_k127_8864818_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000002326 210.0
TH1_k127_8864818_4 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000006821 211.0
TH1_k127_8864818_5 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000471 192.0
TH1_k127_8864818_6 heat shock protein binding - - - 0.0000000000000000000000000000000000006809 151.0
TH1_k127_8864818_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000004107 133.0
TH1_k127_8882055_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 4.29e-254 789.0
TH1_k127_8882055_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 6.926e-236 749.0
TH1_k127_8882055_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.031e-233 728.0
TH1_k127_8882055_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 358.0
TH1_k127_8882055_4 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 259.0
TH1_k127_8882055_5 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001612 246.0
TH1_k127_8882055_6 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000008916 239.0
TH1_k127_8882055_7 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000923 128.0
TH1_k127_8915361_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.975e-206 653.0
TH1_k127_8915361_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 306.0
TH1_k127_8915361_2 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000002009 212.0
TH1_k127_8915361_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000002823 52.0
TH1_k127_8929946_0 CobB/CobQ-like glutamine amidotransferase domain K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 522.0
TH1_k127_8929946_1 TonB-dependent Receptor Plug Domain K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 429.0
TH1_k127_8929946_2 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000002421 176.0
TH1_k127_8940951_0 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 426.0
TH1_k127_8940951_1 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 306.0
TH1_k127_8940951_2 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000000000000002432 100.0
TH1_k127_8940951_3 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000818 81.0
TH1_k127_8940951_4 Type II secretion system protein G K02456 - - 0.00004955 49.0
TH1_k127_8943934_0 Methyl-viologen-reducing hydrogenase, delta subunit K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1030.0
TH1_k127_8943934_1 FAD dependent oxidoreductase K16885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 531.0
TH1_k127_8943934_2 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000001736 173.0
TH1_k127_8943934_3 Fumarate reductase flavoprotein C-term K00394 - 1.8.99.2 0.000000291 52.0
TH1_k127_8961802_0 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 340.0
TH1_k127_8961802_1 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003602 274.0
TH1_k127_8961802_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000003553 81.0
TH1_k127_8961802_3 domain protein - - - 0.0000000000000221 79.0
TH1_k127_9002112_0 Flavodoxin - - - 1.383e-200 630.0
TH1_k127_9002112_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 534.0
TH1_k127_9002112_11 GRIP domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005829,GO:0006810,GO:0006892,GO:0006893,GO:0006950,GO:0008104,GO:0008150,GO:0009987,GO:0012505,GO:0015031,GO:0015833,GO:0016192,GO:0033036,GO:0033554,GO:0034613,GO:0034976,GO:0042886,GO:0043001,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0048193,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051716,GO:0061951,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0072659,GO:0090150,GO:0098876,GO:1990778 - 0.00006407 57.0
TH1_k127_9002112_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 323.0
TH1_k127_9002112_3 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 306.0
TH1_k127_9002112_4 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000000000287 207.0
TH1_k127_9002112_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000002354 194.0
TH1_k127_9002112_6 Cold shock K03704 - - 0.00000000000000000000000001307 109.0
TH1_k127_9002112_7 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000157 79.0
TH1_k127_9002112_8 Fe-S protein K06938 - - 0.0000000007086 61.0
TH1_k127_9002112_9 heat shock protein binding K05516 - - 0.00000002954 66.0
TH1_k127_9044667_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 503.0
TH1_k127_9044667_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 496.0
TH1_k127_9044667_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 398.0
TH1_k127_9044667_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 335.0
TH1_k127_9044667_4 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000002339 190.0
TH1_k127_9051931_0 transferase activity, transferring glycosyl groups K01179,K01356,K13735,K21449 - 3.2.1.4,3.4.21.88 0.00000000000000000000000000000000000000000000000000000000001105 231.0
TH1_k127_9051931_1 competence protein COMEC - - - 0.0000000000000000000000000000000000000001069 164.0
TH1_k127_9051931_2 von Willebrand factor type A domain - - - 0.0000000000000000000789 94.0
TH1_k127_9067000_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.111e-275 859.0
TH1_k127_9067000_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 498.0
TH1_k127_9067000_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000001054 224.0
TH1_k127_9067000_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000007276 183.0
TH1_k127_9067000_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000762 159.0
TH1_k127_9067000_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000002902 88.0
TH1_k127_9071455_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 605.0
TH1_k127_9071455_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 599.0
TH1_k127_9071455_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 438.0
TH1_k127_9071455_3 elongation factor Tu domain 2 protein K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 316.0
TH1_k127_9071455_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000009436 207.0
TH1_k127_9071455_5 thiamine diphosphate biosynthetic process K03149,K03154 - 2.8.1.10 0.000000000000009395 75.0
TH1_k127_9079644_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 8.069e-199 633.0
TH1_k127_9079644_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 604.0
TH1_k127_9079644_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000002404 263.0
TH1_k127_9079644_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000003015 93.0
TH1_k127_9079644_4 domain, Protein K00703,K07082 - 2.4.1.21 0.0000003604 57.0
TH1_k127_9080866_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 575.0
TH1_k127_9080866_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000000000000000000001042 240.0
TH1_k127_9080866_2 Histidine kinase - - - 0.00000000000000000000000000004439 135.0
TH1_k127_9118377_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 570.0
TH1_k127_9118377_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 282.0
TH1_k127_9118377_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001684 205.0
TH1_k127_9118377_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000001783 151.0
TH1_k127_9118377_4 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000002467 120.0
TH1_k127_9118377_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000352 110.0
TH1_k127_9118377_6 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000008645 67.0
TH1_k127_9134937_0 Aminotransferase class-III K01845 - 5.4.3.8 1.796e-204 642.0
TH1_k127_9134937_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 609.0
TH1_k127_9134937_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 420.0
TH1_k127_9134937_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005195 245.0
TH1_k127_9134937_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000002067 201.0
TH1_k127_9134937_5 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000007963 152.0
TH1_k127_9166409_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 549.0
TH1_k127_9166409_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 481.0
TH1_k127_9166409_2 protein transport across the cell outer membrane K02452,K02463 - - 0.000000000000000000000000000000000000001287 158.0
TH1_k127_9166409_3 Type II and III secretion system protein K02453 - - 0.0000000000000000002769 93.0
TH1_k127_9173675_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 570.0
TH1_k127_9173675_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 528.0
TH1_k127_9173675_2 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 350.0
TH1_k127_9192914_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 456.0
TH1_k127_9192914_1 PFAM cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 318.0
TH1_k127_9192914_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000015 218.0
TH1_k127_9192914_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 0.00000000000000000000000000000000000000000000000223 178.0
TH1_k127_9192914_4 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000000000000000000000000007985 148.0
TH1_k127_9194689_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.226e-199 635.0
TH1_k127_9194689_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000001123 197.0
TH1_k127_9194689_2 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000001301 147.0
TH1_k127_9194689_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000003437 111.0
TH1_k127_9197047_0 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007938 291.0
TH1_k127_9197047_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001842 262.0
TH1_k127_9197047_2 histidine kinase, HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000005996 205.0
TH1_k127_9204664_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 1.435e-206 659.0
TH1_k127_9204664_1 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001655 282.0
TH1_k127_9209578_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 485.0
TH1_k127_9209578_1 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 388.0
TH1_k127_9209578_2 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000008086 158.0
TH1_k127_9209578_3 HupE / UreJ protein - - - 0.00000000000000000000000000000000000007329 152.0
TH1_k127_9209578_4 - - - - 0.0000000000004363 70.0
TH1_k127_9209578_5 radical SAM domain protein K06871 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 - 0.000000003351 60.0
TH1_k127_9209578_6 - - - - 0.00000009365 57.0
TH1_k127_9213322_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.197e-194 614.0
TH1_k127_9213322_1 Phosphonate ABC transporter, periplasmic K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 299.0
TH1_k127_9213322_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000001201 246.0
TH1_k127_9213322_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000003536 225.0
TH1_k127_9213322_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000001525 128.0
TH1_k127_9213322_6 histidine kinase dimerisation and phosphoacceptor region - - - 0.0000000000000001545 91.0
TH1_k127_9278809_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 478.0
TH1_k127_9278809_1 PFAM 4Fe-4S K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 430.0
TH1_k127_9278809_2 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000004588 218.0
TH1_k127_9278809_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000008026 199.0
TH1_k127_9283549_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 374.0
TH1_k127_9283549_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000117 284.0
TH1_k127_9283549_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000001796 104.0
TH1_k127_9283549_3 SpoVT / AbrB like domain - - - 0.000000000000001105 79.0
TH1_k127_9325756_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.748e-254 799.0
TH1_k127_9325756_1 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 350.0
TH1_k127_9325756_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 298.0
TH1_k127_9325756_3 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000000005069 201.0
TH1_k127_9325756_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000000000000000000000000000000000000000000000002264 189.0
TH1_k127_9325756_5 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000005039 173.0
TH1_k127_9325756_6 - - - - 0.000000002609 59.0
TH1_k127_9336627_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 443.0
TH1_k127_9336627_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000001631 234.0
TH1_k127_9336627_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000001921 173.0
TH1_k127_9336627_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000004115 121.0
TH1_k127_9336627_4 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000007252 97.0
TH1_k127_9356889_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1707.0
TH1_k127_9356889_1 Acyl-transferase - - - 0.00000000000000000000007257 111.0
TH1_k127_9356889_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000001211 101.0
TH1_k127_9394638_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 9.676e-245 768.0
TH1_k127_9394638_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 518.0
TH1_k127_9394638_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 324.0
TH1_k127_9394638_3 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001361 249.0
TH1_k127_9394638_4 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000057 237.0
TH1_k127_9394638_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000001791 188.0
TH1_k127_9394638_6 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000000000197 123.0
TH1_k127_9394638_7 Predicted RNA-binding protein - - - 0.000000000000000002917 87.0
TH1_k127_9394638_8 oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000007698 78.0
TH1_k127_9394638_9 Ribosomal RNA adenine dimethylase - - - 0.00000005752 61.0
TH1_k127_9456384_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1278.0
TH1_k127_9456384_1 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 329.0
TH1_k127_9456384_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001153 244.0
TH1_k127_9456384_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000006342 190.0
TH1_k127_9456384_4 Prokaryotic cytochrome b561 K00127 - - 0.0000000000000000000000000001775 121.0
TH1_k127_947523_0 PFAM Polysulphide reductase, NrfD K00185 - - 1.222e-227 717.0
TH1_k127_947523_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 510.0
TH1_k127_947523_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 471.0
TH1_k127_947523_3 PFAM 4Fe-4S K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 413.0
TH1_k127_947523_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000122 167.0
TH1_k127_947523_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000198 145.0
TH1_k127_947523_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000007499 118.0
TH1_k127_947523_7 cyclic nucleotide-binding K01420,K21563 - - 0.0000000000000000000001998 107.0
TH1_k127_947523_8 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000002196 71.0
TH1_k127_947523_9 PFAM Cyclic nucleotide-binding K10914 - - 0.00000000328 64.0
TH1_k127_9481227_0 response regulator - - - 0.0000000000000000000000000004197 117.0
TH1_k127_9481227_1 PFAM response regulator receiver - - - 0.000000000000000000000000003684 115.0
TH1_k127_9481227_2 Histidine kinase - - - 0.000000000000000000000008131 109.0
TH1_k127_9481510_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 588.0
TH1_k127_9481510_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 362.0
TH1_k127_9481510_2 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000087 164.0
TH1_k127_9481510_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000008646 87.0
TH1_k127_9481510_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000003809 69.0
TH1_k127_9499783_0 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000004267 218.0
TH1_k127_9499783_1 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000002722 148.0
TH1_k127_9517687_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 5.493e-293 910.0
TH1_k127_9517687_1 Protein of unknown function, DUF255 K06888 - - 1.89e-232 736.0
TH1_k127_9517687_11 transferase activity, transferring glycosyl groups - - - 0.0000002296 59.0
TH1_k127_9517687_2 Restriction endonuclease K07448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 518.0
TH1_k127_9517687_3 ZIP Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 402.0
TH1_k127_9517687_4 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000002278 148.0
TH1_k127_9517687_5 Cytochrome c K08738 - - 0.000000000000000000000000000000004846 131.0
TH1_k127_9517687_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000002998 121.0
TH1_k127_9517687_9 - - - - 0.0000000000003125 73.0
TH1_k127_9527784_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002696 278.0
TH1_k127_9527784_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000001232 156.0
TH1_k127_9527784_2 methyltransferase K15256 - - 0.0000000000000000000000000000001059 131.0
TH1_k127_9527784_3 (ABC) transporter K06147,K11085 - - 0.0000000000000000000000000000007674 123.0
TH1_k127_9527784_4 Glycosyl transferases group 1 - - - 0.000001204 59.0
TH1_k127_9559800_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 420.0
TH1_k127_9559800_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 401.0
TH1_k127_9559800_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 338.0
TH1_k127_9559800_3 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004388 279.0
TH1_k127_9559800_4 PFAM Class I peptide chain release factor - - - 0.00000000000000000000000000000000000007935 146.0
TH1_k127_9559800_5 Rubrerythrin - - - 0.000000003032 63.0
TH1_k127_9583021_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000423 220.0
TH1_k127_9583021_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000001755 83.0
TH1_k127_9591504_0 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 419.0
TH1_k127_9591504_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 360.0
TH1_k127_9591504_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004375 277.0
TH1_k127_9597_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000001157 249.0
TH1_k127_9597_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000623 144.0
TH1_k127_9601814_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 4.858e-201 642.0
TH1_k127_9601814_1 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000000007233 119.0
TH1_k127_9601814_2 periplasmic or secreted lipoprotein - - - 0.00000000000000000000000006383 107.0
TH1_k127_9601814_3 mercury ion transmembrane transporter activity K07213 - - 0.0000000000001806 74.0
TH1_k127_9601814_6 Belongs to the SOS response-associated peptidase family - - - 0.0001777 46.0
TH1_k127_9615854_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 377.0
TH1_k127_9615854_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000002235 222.0
TH1_k127_964101_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.095e-214 687.0
TH1_k127_964101_1 AAA ATPase domain - - - 0.00000005286 63.0
TH1_k127_974066_0 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000002609 159.0
TH1_k127_974066_1 Integral membrane protein TerC family - - - 0.00000000000001259 78.0
TH1_k127_974066_2 Two component transcriptional regulator, LuxR family K02282 - - 0.0000000000005154 81.0
TH1_k127_974066_3 DnaJ molecular chaperone homology domain - - - 0.00000001632 65.0
TH1_k127_989785_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 328.0
TH1_k127_989785_1 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 320.0
TH1_k127_989785_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003707 274.0
TH1_k127_989785_3 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000005035 195.0
TH1_k127_990436_0 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000002941 231.0
TH1_k127_990436_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000001277 176.0
TH1_k127_990436_2 oxidoreductase gamma subunit K00177 - 1.2.7.3 0.00000000000000000000000000000000000002613 151.0
TH1_k127_990436_3 PFAM DsrE DsrF-like family - - - 0.0000001258 59.0
TH1_k127_990436_4 - - - - 0.0003561 48.0
TH1_k127_992450_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1523.0
TH1_k127_992450_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.104e-275 864.0
TH1_k127_992450_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000001214 72.0