Overview

ID MAG03852
Name TH1_bin.20
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus UBA6898
Species
Assembly information
Completeness (%) 94.47
Contamination (%) 2.44
GC content (%) 49.0
N50 (bp) 12,830
Genome size (bp) 2,214,994

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2160

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_106484_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 308.0
TH1_k127_106484_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 287.0
TH1_k127_106484_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006401 276.0
TH1_k127_106484_3 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004585 258.0
TH1_k127_106484_4 PFAM PHP domain - - - 0.00000000000000000000000000000000001447 143.0
TH1_k127_106484_5 Mut7-C RNAse domain K09122 - - 0.00000000001826 65.0
TH1_k127_1075001_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.594e-278 876.0
TH1_k127_1075001_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 9.062e-275 870.0
TH1_k127_1075001_10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 327.0
TH1_k127_1075001_11 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 331.0
TH1_k127_1075001_12 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000493 289.0
TH1_k127_1075001_13 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004487 282.0
TH1_k127_1075001_14 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000008282 259.0
TH1_k127_1075001_15 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000004039 246.0
TH1_k127_1075001_16 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000001159 153.0
TH1_k127_1075001_17 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000002291 139.0
TH1_k127_1075001_18 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000002699 100.0
TH1_k127_1075001_19 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000007383 90.0
TH1_k127_1075001_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.88e-258 823.0
TH1_k127_1075001_20 - - - - 0.000000000000000002882 90.0
TH1_k127_1075001_21 Pilus assembly protein, PilP K02665 - - 0.00000000000005797 78.0
TH1_k127_1075001_22 COG3167 Tfp pilus assembly protein PilO K02664 - - 0.000000000005245 74.0
TH1_k127_1075001_23 Protein of unknown function (DUF721) - - - 0.00006615 51.0
TH1_k127_1075001_3 Protein of unknown function, DUF255 K06888 - - 3.824e-240 756.0
TH1_k127_1075001_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 578.0
TH1_k127_1075001_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 465.0
TH1_k127_1075001_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 422.0
TH1_k127_1075001_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 415.0
TH1_k127_1075001_8 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 381.0
TH1_k127_1075001_9 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006771 336.0
TH1_k127_1122485_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1096.0
TH1_k127_1122485_1 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 496.0
TH1_k127_1122485_2 Catalyzes the synthesis of activated sulfate K00860 GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002103 263.0
TH1_k127_1122485_3 sulfate ABC transporter K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001795 250.0
TH1_k127_1122485_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000358 243.0
TH1_k127_1122485_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002454 213.0
TH1_k127_1122485_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000000000000000000000000001402 163.0
TH1_k127_1122485_7 Transcriptional regulator, BadM Rrf2 family - - - 0.00000000000000000000000000000000000000003401 158.0
TH1_k127_1122485_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001413 79.0
TH1_k127_1122485_9 - - - - 0.0000000000000001886 82.0
TH1_k127_1138903_0 Large extracellular alpha-helical protein K06894 - - 0.0 2207.0
TH1_k127_1138903_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 8.083e-225 717.0
TH1_k127_1138903_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 560.0
TH1_k127_1138903_3 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 529.0
TH1_k127_1138903_4 Phosphomethylpyrimidine kinase K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000007599 221.0
TH1_k127_1138903_5 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000007051 164.0
TH1_k127_1138903_6 response regulator, receiver - - - 0.000000000000000000000000000000000006354 151.0
TH1_k127_1138903_7 Response regulator receiver - - - 0.00000000005466 74.0
TH1_k127_1230445_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 570.0
TH1_k127_1230445_1 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 478.0
TH1_k127_1230445_2 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000006656 201.0
TH1_k127_1274438_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.505e-241 758.0
TH1_k127_1274438_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 423.0
TH1_k127_1274438_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 368.0
TH1_k127_1274438_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 358.0
TH1_k127_1274438_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000005111 260.0
TH1_k127_1286241_0 MULE transposase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000139 233.0
TH1_k127_1286241_1 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000002854 163.0
TH1_k127_1286241_2 PFAM transposase, mutator - - - 0.000000000000000000000000000001357 123.0
TH1_k127_1286241_3 regulation of RNA biosynthetic process - - - 0.00000000000000004798 87.0
TH1_k127_1286241_4 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000008112 78.0
TH1_k127_1286241_5 Crp-like helix-turn-helix domain - - - 0.00000000000335 76.0
TH1_k127_1286241_6 - - - - 0.00000000001147 67.0
TH1_k127_1286241_7 Chemotaxis sensory transducer K03406 - - 0.0000000001754 65.0
TH1_k127_1286241_8 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000815 54.0
TH1_k127_1294300_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.065e-196 619.0
TH1_k127_1294300_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 602.0
TH1_k127_1294300_2 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000003454 141.0
TH1_k127_1296502_0 COG0058 Glucan phosphorylase - - - 2.843e-261 815.0
TH1_k127_1296502_1 chelatase, subunit ChlI K07391 - - 1.015e-209 662.0
TH1_k127_1296502_10 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000001848 200.0
TH1_k127_1296502_11 heme-binding sites - - - 0.0000000000000000000000000000000000000001963 159.0
TH1_k127_1296502_12 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000002063 149.0
TH1_k127_1296502_13 heat shock protein binding - - - 0.00000000000000000000000000000000000004448 154.0
TH1_k127_1296502_14 formate dehydrogenase - - - 0.0000000000000000000000000000000005833 142.0
TH1_k127_1296502_15 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000002975 131.0
TH1_k127_1296502_16 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000005215 128.0
TH1_k127_1296502_17 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000005871 126.0
TH1_k127_1296502_18 TM2 domain - - - 0.0000000000000000000000000002046 118.0
TH1_k127_1296502_19 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000001353 113.0
TH1_k127_1296502_2 Histidine kinase - - - 7.507e-195 648.0
TH1_k127_1296502_20 Belongs to the 'phage' integrase family - - - 0.0000000000001105 75.0
TH1_k127_1296502_21 exodeoxyribonuclease I activity - - - 0.0000000007582 64.0
TH1_k127_1296502_22 4Fe-4S double cluster binding domain - - - 0.0000009963 51.0
TH1_k127_1296502_24 microtubule plus-end directed mitotic chromosome migration K03257,K11498 GO:0000070,GO:0000075,GO:0000226,GO:0000228,GO:0000278,GO:0000280,GO:0000775,GO:0000776,GO:0000777,GO:0000778,GO:0000779,GO:0000780,GO:0000793,GO:0000794,GO:0000819,GO:0000940,GO:0001932,GO:0001934,GO:0002376,GO:0002478,GO:0002495,GO:0002504,GO:0003674,GO:0003774,GO:0003777,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005819,GO:0005828,GO:0005829,GO:0005856,GO:0005871,GO:0005874,GO:0005875,GO:0005876,GO:0006810,GO:0006890,GO:0006928,GO:0006996,GO:0007010,GO:0007017,GO:0007018,GO:0007049,GO:0007051,GO:0007052,GO:0007059,GO:0007079,GO:0007080,GO:0007088,GO:0007091,GO:0007093,GO:0007094,GO:0007346,GO:0008017,GO:0008092,GO:0008104,GO:0008150,GO:0008574,GO:0008608,GO:0009893,GO:0009896,GO:0009987,GO:0010562,GO:0010564,GO:0010604,GO:0010638,GO:0010639,GO:0010948,GO:0010965,GO:0015630,GO:0015631,GO:0016043,GO:0016192,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019220,GO:0019222,GO:0019882,GO:0019884,GO:0019886,GO:0019899,GO:0019900,GO:0019901,GO:0022402,GO:0022607,GO:0030071,GO:0030496,GO:0031323,GO:0031325,GO:0031331,GO:0031399,GO:0031401,GO:0031577,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032436,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033046,GO:0033047,GO:0033048,GO:0033674,GO:0034508,GO:0034622,GO:0042325,GO:0042327,GO:0042623,GO:0043085,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043515,GO:0043549,GO:0043933,GO:0044085,GO:0044093,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044770,GO:0044772,GO:0044784,GO:0044877,GO:0045184,GO:0045732,GO:0045786,GO:0045787,GO:0045839,GO:0045840,GO:0045841,GO:0045842,GO:0045859,GO:0045860,GO:0045862,GO:0045930,GO:0045931,GO:0045937,GO:0048002,GO:0048193,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050000,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051233,GO:0051234,GO:0051246,GO:0051247,GO:0051276,GO:0051303,GO:0051305,GO:0051310,GO:0051315,GO:0051338,GO:0051347,GO:0051382,GO:0051383,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0051726,GO:0051781,GO:0051783,GO:0051784,GO:0051785,GO:0051983,GO:0051984,GO:0051985,GO:0051987,GO:0051988,GO:0060255,GO:0062033,GO:0065003,GO:0065004,GO:0065007,GO:0065009,GO:0070013,GO:0070925,GO:0071173,GO:0071174,GO:0071824,GO:0071840,GO:0072686,GO:0080090,GO:0090068,GO:0098687,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099606,GO:0099607,GO:0140014,GO:1901800,GO:1901970,GO:1901987,GO:1901988,GO:1901989,GO:1901990,GO:1901991,GO:1901992,GO:1902099,GO:1902100,GO:1902101,GO:1902850,GO:1903047,GO:1903052,GO:1903364,GO:1905818,GO:1905819,GO:1905820,GO:1990023,GO:1990939,GO:2000816,GO:2001251,GO:2001252 - 0.00001581 59.0
TH1_k127_1296502_3 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 430.0
TH1_k127_1296502_4 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 380.0
TH1_k127_1296502_5 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 292.0
TH1_k127_1296502_6 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002797 259.0
TH1_k127_1296502_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000001153 239.0
TH1_k127_1296502_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000001735 224.0
TH1_k127_1296502_9 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000012 203.0
TH1_k127_1306478_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.994e-226 710.0
TH1_k127_1306478_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 2.527e-217 679.0
TH1_k127_1306478_10 ThiS family K03636 - - 0.0000000000000000000000000000000007285 133.0
TH1_k127_1306478_11 NIL - - - 0.0000000000000000000000000003086 115.0
TH1_k127_1306478_2 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 599.0
TH1_k127_1306478_3 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 519.0
TH1_k127_1306478_4 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 508.0
TH1_k127_1306478_5 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 289.0
TH1_k127_1306478_6 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 286.0
TH1_k127_1306478_7 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001482 283.0
TH1_k127_1306478_8 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001601 287.0
TH1_k127_1306478_9 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000004188 176.0
TH1_k127_1314474_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 8.075e-202 643.0
TH1_k127_1314474_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 534.0
TH1_k127_1314474_10 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000001561 245.0
TH1_k127_1314474_11 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000002047 223.0
TH1_k127_1314474_12 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000003767 173.0
TH1_k127_1314474_13 Male sterility protein - - - 0.00000000000000000000006466 108.0
TH1_k127_1314474_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 510.0
TH1_k127_1314474_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 459.0
TH1_k127_1314474_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 416.0
TH1_k127_1314474_5 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 375.0
TH1_k127_1314474_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 370.0
TH1_k127_1314474_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 364.0
TH1_k127_1314474_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 326.0
TH1_k127_1314474_9 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001346 263.0
TH1_k127_1336192_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1031.0
TH1_k127_1336192_1 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 549.0
TH1_k127_1336192_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 531.0
TH1_k127_1336192_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 482.0
TH1_k127_1336192_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 325.0
TH1_k127_1336192_5 PFAM carboxyl transferase K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000003286 237.0
TH1_k127_1336192_6 4Fe-4S binding domain - - - 0.0000000000001138 72.0
TH1_k127_1336192_7 Recombinase zinc beta ribbon domain - - - 0.00005496 50.0
TH1_k127_1342794_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.983e-237 750.0
TH1_k127_1342794_1 GAF domain - - - 2.049e-204 687.0
TH1_k127_1342794_10 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000002261 190.0
TH1_k127_1342794_11 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000000001702 170.0
TH1_k127_1342794_12 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000001583 161.0
TH1_k127_1342794_13 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000002181 153.0
TH1_k127_1342794_14 phosphorelay signal transduction system - - - 0.000000000000000000000000000000004474 136.0
TH1_k127_1342794_15 Putative regulatory protein - - - 0.0000000000000000000002716 100.0
TH1_k127_1342794_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 529.0
TH1_k127_1342794_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 436.0
TH1_k127_1342794_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 375.0
TH1_k127_1342794_5 PFAM ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 347.0
TH1_k127_1342794_6 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 308.0
TH1_k127_1342794_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 305.0
TH1_k127_1342794_8 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002578 252.0
TH1_k127_1342794_9 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000001485 242.0
TH1_k127_138268_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 601.0
TH1_k127_138268_1 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 496.0
TH1_k127_138268_10 Mate efflux family protein - - - 0.0005693 43.0
TH1_k127_138268_11 Sporulation related domain K03749 GO:0000910,GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0030428,GO:0032153,GO:0032506,GO:0042834,GO:0044464,GO:0051301,GO:0097367 - 0.0009137 51.0
TH1_k127_138268_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 396.0
TH1_k127_138268_3 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 344.0
TH1_k127_138268_4 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 322.0
TH1_k127_138268_5 pyridoxamine 5-phosphate oxidase-related K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008975 245.0
TH1_k127_138268_6 NAD(P)H dehydrogenase K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000003397 229.0
TH1_k127_138268_7 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000002153 189.0
TH1_k127_138268_8 DDE domain K07497 - - 0.000000000001102 68.0
TH1_k127_138268_9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000019 60.0
TH1_k127_1385676_0 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 415.0
TH1_k127_1385676_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000006574 191.0
TH1_k127_1385676_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000002039 169.0
TH1_k127_1385676_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000302 85.0
TH1_k127_1385676_4 iron-sulfur cluster assembly - - - 0.000007835 51.0
TH1_k127_1386680_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.156e-267 830.0
TH1_k127_1386680_1 carboxylase K01965,K01968 - 6.4.1.3,6.4.1.4 7.01e-260 816.0
TH1_k127_1386680_2 GYD domain - - - 0.00000005577 54.0
TH1_k127_1412278_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 463.0
TH1_k127_1412278_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 453.0
TH1_k127_1412278_10 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000003984 174.0
TH1_k127_1412278_11 TIGRFAM Addiction module antidote protein, HigA - - - 0.0000000000000000000000000000000000000001551 152.0
TH1_k127_1412278_12 PFAM Plasmid maintenance system killer K07334 - - 0.0000000000000000000000000000000000006169 141.0
TH1_k127_1412278_13 YGGT family K02221 - - 0.000000000000000000000000000000004246 131.0
TH1_k127_1412278_14 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000004287 135.0
TH1_k127_1412278_15 PFAM response regulator receiver - - - 0.000000000000000000000000007075 114.0
TH1_k127_1412278_16 membrane - - - 0.00000000000000000000001748 112.0
TH1_k127_1412278_2 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 323.0
TH1_k127_1412278_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001165 276.0
TH1_k127_1412278_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002497 244.0
TH1_k127_1412278_5 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000009288 209.0
TH1_k127_1412278_6 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000004822 208.0
TH1_k127_1412278_7 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000111 204.0
TH1_k127_1412278_8 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000001253 215.0
TH1_k127_1412278_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000001841 207.0
TH1_k127_1451710_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 417.0
TH1_k127_1451710_1 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
TH1_k127_1451710_2 Universal stress protein family K07090 - - 0.00000000000000000000000000000000000000003409 166.0
TH1_k127_1451710_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000000001499 113.0
TH1_k127_148095_0 FecR protein - - - 1.013e-298 950.0
TH1_k127_148095_1 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 625.0
TH1_k127_148095_10 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000007773 94.0
TH1_k127_148095_11 thiolester hydrolase activity - - - 0.00000000001677 66.0
TH1_k127_148095_2 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 397.0
TH1_k127_148095_3 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 381.0
TH1_k127_148095_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000001051 244.0
TH1_k127_148095_5 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000008705 214.0
TH1_k127_148095_6 - - - - 0.00000000000000000000000000000000000000000000000000000002506 208.0
TH1_k127_148095_7 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000000000000000000000000000000003908 199.0
TH1_k127_148095_8 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.000000000000000000000000000000006173 133.0
TH1_k127_148095_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000003978 113.0
TH1_k127_1494350_0 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 521.0
TH1_k127_1494350_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 440.0
TH1_k127_1494350_2 response regulator K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 407.0
TH1_k127_1494350_3 domain protein K01637,K20276 - 4.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 329.0
TH1_k127_1494350_4 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000001762 193.0
TH1_k127_1494350_5 Aspartyl-tRNA amidotransferase K09117 - - 0.000000000000000000000000000000000002035 143.0
TH1_k127_1494350_6 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000005275 157.0
TH1_k127_1494350_7 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000008478 87.0
TH1_k127_1494350_8 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000004077 72.0
TH1_k127_1503412_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 3.347e-196 625.0
TH1_k127_1503412_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 419.0
TH1_k127_1503412_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 318.0
TH1_k127_1503412_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000001947 140.0
TH1_k127_1503412_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000132 112.0
TH1_k127_1503412_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000001982 95.0
TH1_k127_1503412_6 TIGRFAM transcriptional regulator, AbrB family - - - 0.000002107 52.0
TH1_k127_153675_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.898e-262 817.0
TH1_k127_153675_1 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 2.01e-225 720.0
TH1_k127_153675_2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 391.0
TH1_k127_153675_3 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 321.0
TH1_k127_153675_4 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 286.0
TH1_k127_153675_5 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000006471 218.0
TH1_k127_1582494_0 NADH-quinone oxidoreductase K00341 - 1.6.5.3 2.388e-242 764.0
TH1_k127_1582494_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 598.0
TH1_k127_1582494_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 449.0
TH1_k127_1582494_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 405.0
TH1_k127_1582494_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000003544 158.0
TH1_k127_1582494_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000177 151.0
TH1_k127_1582494_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000001435 130.0
TH1_k127_1582494_7 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000001271 99.0
TH1_k127_1582494_8 GTP-binding protein TypA K06207 - - 0.00000000000000000004097 91.0
TH1_k127_1582494_9 SpoVT / AbrB like domain - - - 0.00000000000000003386 84.0
TH1_k127_1591049_0 protein secretion K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 564.0
TH1_k127_1591049_1 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 529.0
TH1_k127_1591049_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000002228 190.0
TH1_k127_1621051_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1113.0
TH1_k127_1621051_1 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 527.0
TH1_k127_1621051_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 369.0
TH1_k127_1621051_3 membrane K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 368.0
TH1_k127_1621051_4 protein with SCP PR1 domains - - - 0.0000000000000000000000000000000000000000000006088 173.0
TH1_k127_1621051_6 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000857 94.0
TH1_k127_1621051_7 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000004063 70.0
TH1_k127_1621051_8 oxidoreductase activity, acting on iron-sulfur proteins as donors K02588 - 1.18.6.1 0.000000000001977 67.0
TH1_k127_1621051_9 Binds directly to 16S ribosomal RNA K02968 - - 0.00000004114 58.0
TH1_k127_1683519_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 449.0
TH1_k127_1683519_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 341.0
TH1_k127_1683519_2 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
TH1_k127_1683519_3 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006599 278.0
TH1_k127_1683519_4 Methylamine utilisation protein MauE - - - 0.000000000000002454 83.0
TH1_k127_1683519_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000007717 63.0
TH1_k127_1695405_0 Telomere recombination K04656 - - 1.527e-243 776.0
TH1_k127_1695405_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 4.559e-232 731.0
TH1_k127_1695405_10 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 355.0
TH1_k127_1695405_11 PFAM MscS Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 342.0
TH1_k127_1695405_12 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 342.0
TH1_k127_1695405_13 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 345.0
TH1_k127_1695405_14 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 345.0
TH1_k127_1695405_15 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 323.0
TH1_k127_1695405_16 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 324.0
TH1_k127_1695405_17 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 316.0
TH1_k127_1695405_19 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 307.0
TH1_k127_1695405_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 542.0
TH1_k127_1695405_20 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 295.0
TH1_k127_1695405_21 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002159 274.0
TH1_k127_1695405_22 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001357 253.0
TH1_k127_1695405_23 Redoxin K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000004128 235.0
TH1_k127_1695405_24 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000004353 197.0
TH1_k127_1695405_25 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000004534 181.0
TH1_k127_1695405_26 PFAM FecR protein - - - 0.0000000000000000000000000000000000000000001531 183.0
TH1_k127_1695405_27 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000000000000000000000000000000000002088 164.0
TH1_k127_1695405_28 PKD domain - - - 0.0000000000000000000000000000000001078 154.0
TH1_k127_1695405_29 Cache domain - - - 0.0000000000000000000000000000000005986 141.0
TH1_k127_1695405_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 514.0
TH1_k127_1695405_30 nickel cation binding K04651,K19640 - - 0.000000000000000000000000000001606 125.0
TH1_k127_1695405_31 - - - - 0.000000000000000000000000000003046 138.0
TH1_k127_1695405_32 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000001413 113.0
TH1_k127_1695405_33 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000001288 106.0
TH1_k127_1695405_34 Rubrerythrin - - - 0.000000000000000000002045 100.0
TH1_k127_1695405_35 UPF0761 membrane protein K07058 - - 0.0000000000000000006915 96.0
TH1_k127_1695405_36 Tetratricopeptide repeat - - - 0.000000000000000005489 98.0
TH1_k127_1695405_37 outer membrane autotransporter barrel domain - - - 0.00000000000000005075 96.0
TH1_k127_1695405_38 virulence factor - - - 0.000000000000000228 85.0
TH1_k127_1695405_39 domain protein - - - 0.000000000000003193 91.0
TH1_k127_1695405_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 486.0
TH1_k127_1695405_40 Tetratricopeptide repeat - - - 0.00000000000001544 83.0
TH1_k127_1695405_41 Cytochrome c K02305 - - 0.0000000000005561 73.0
TH1_k127_1695405_42 - - - - 0.000000000002494 72.0
TH1_k127_1695405_44 Tetratricopeptide repeat - - - 0.000000001542 61.0
TH1_k127_1695405_45 - - - - 0.0000002932 61.0
TH1_k127_1695405_46 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.0000003216 61.0
TH1_k127_1695405_47 bacterial-type flagellum-dependent cell motility - - - 0.00002267 57.0
TH1_k127_1695405_5 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 469.0
TH1_k127_1695405_6 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 422.0
TH1_k127_1695405_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 408.0
TH1_k127_1695405_8 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 374.0
TH1_k127_1695405_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 352.0
TH1_k127_1704075_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 1.164e-262 819.0
TH1_k127_1704075_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 510.0
TH1_k127_1750623_0 Major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 595.0
TH1_k127_1750623_1 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001735 254.0
TH1_k127_1750623_2 4Fe-4S binding domain - - - 0.00000000000000000000008761 108.0
TH1_k127_1750747_0 lipopolysaccharide transport K22110 - - 0.0 1146.0
TH1_k127_1750747_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 422.0
TH1_k127_1750747_2 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 409.0
TH1_k127_1750747_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 394.0
TH1_k127_1750747_4 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 319.0
TH1_k127_1750747_5 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003643 279.0
TH1_k127_1750747_6 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003022 263.0
TH1_k127_1750747_7 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000002644 178.0
TH1_k127_1750747_8 cell redox homeostasis - - - 0.000000000000000000000000000007043 119.0
TH1_k127_1750747_9 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000003872 76.0
TH1_k127_177746_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1085.0
TH1_k127_177746_1 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1084.0
TH1_k127_177746_10 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 370.0
TH1_k127_177746_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 348.0
TH1_k127_177746_12 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 353.0
TH1_k127_177746_13 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 353.0
TH1_k127_177746_14 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 310.0
TH1_k127_177746_15 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 314.0
TH1_k127_177746_16 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 302.0
TH1_k127_177746_17 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 293.0
TH1_k127_177746_18 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000132 274.0
TH1_k127_177746_19 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001877 273.0
TH1_k127_177746_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 618.0
TH1_k127_177746_20 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000009122 267.0
TH1_k127_177746_21 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004784 265.0
TH1_k127_177746_22 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000004548 243.0
TH1_k127_177746_23 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000004171 235.0
TH1_k127_177746_24 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000007594 218.0
TH1_k127_177746_25 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000006917 204.0
TH1_k127_177746_26 Hit family K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000002311 202.0
TH1_k127_177746_27 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000002361 204.0
TH1_k127_177746_28 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000001941 214.0
TH1_k127_177746_29 - - - - 0.000000000000000000000000000000000000000000000000006228 204.0
TH1_k127_177746_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 589.0
TH1_k127_177746_30 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000001354 195.0
TH1_k127_177746_31 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000000000000000000001537 189.0
TH1_k127_177746_33 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000002059 179.0
TH1_k127_177746_34 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000001083 167.0
TH1_k127_177746_35 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000003267 167.0
TH1_k127_177746_36 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000005317 149.0
TH1_k127_177746_37 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000003253 149.0
TH1_k127_177746_38 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000001599 149.0
TH1_k127_177746_39 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000258 151.0
TH1_k127_177746_4 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 501.0
TH1_k127_177746_40 Thioredoxin-like - - - 0.00000000000000000000000000000000002143 140.0
TH1_k127_177746_41 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000001328 124.0
TH1_k127_177746_42 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000002233 126.0
TH1_k127_177746_43 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K02014,K16087 - - 0.00000000000000000000000000002397 128.0
TH1_k127_177746_44 Hydrolase, P-loop family K06925 - - 0.000000000000000000000000001834 116.0
TH1_k127_177746_45 Ribosomal protein S16 K02959 - - 0.000000000000000000000000002431 113.0
TH1_k127_177746_46 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000004887 113.0
TH1_k127_177746_47 peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.00000000000000000000000001096 121.0
TH1_k127_177746_48 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000002437 108.0
TH1_k127_177746_49 - - - - 0.00000000000000000000001151 111.0
TH1_k127_177746_5 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 475.0
TH1_k127_177746_50 iron-sulfur cluster assembly - - - 0.0000000000000000000001054 99.0
TH1_k127_177746_51 protein secretion K03116,K03117 - - 0.0000000000000474 75.0
TH1_k127_177746_53 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16783,K16785 - - 0.00000000001153 73.0
TH1_k127_177746_54 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000858 63.0
TH1_k127_177746_55 LysM domain - - - 0.000000527 62.0
TH1_k127_177746_56 SurA N-terminal domain K03771 - 5.2.1.8 0.0001773 55.0
TH1_k127_177746_57 - - - - 0.0004566 43.0
TH1_k127_177746_6 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 455.0
TH1_k127_177746_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 415.0
TH1_k127_177746_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 396.0
TH1_k127_177746_9 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 398.0
TH1_k127_1782496_0 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 417.0
TH1_k127_1782496_1 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 349.0
TH1_k127_1782496_10 COG2010 Cytochrome c, mono- and diheme variants K02305 - - 0.00000000000000000006548 91.0
TH1_k127_1782496_13 COG0607 Rhodanese-related sulfurtransferase - - - 0.00002795 50.0
TH1_k127_1782496_14 ABC-type multidrug transport system, permease component K01992 - - 0.00003359 47.0
TH1_k127_1782496_2 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002397 241.0
TH1_k127_1782496_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004661 225.0
TH1_k127_1782496_4 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001366 222.0
TH1_k127_1782496_5 secondary active sulfate transmembrane transporter activity K03321 - - 0.0000000000000000000000000000000000000000001172 171.0
TH1_k127_1782496_6 conserved protein UCP033924 - - - 0.0000000000000000000000000000000000000000244 158.0
TH1_k127_1782496_7 AhpC/TSA family K03564 - 1.11.1.15 0.00000000000000000000000000001254 120.0
TH1_k127_1782496_8 electron transfer activity K05337,K17247 - - 0.0000000000000000000000001204 106.0
TH1_k127_1782496_9 Thioredoxin-like - - - 0.0000000000000000000000001864 113.0
TH1_k127_186478_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 8.144e-197 623.0
TH1_k127_186478_1 Phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 619.0
TH1_k127_186478_10 dolichyl monophosphate biosynthetic process - - - 0.000000000000000000000000000000000166 149.0
TH1_k127_186478_11 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.00000000000000000000000000001764 122.0
TH1_k127_186478_12 Formyl transferase - - - 0.0000000000000000002477 98.0
TH1_k127_186478_2 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 529.0
TH1_k127_186478_3 Hydroxymethylglutaryl-coenzyme A reductase K00021 - 1.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 449.0
TH1_k127_186478_4 Psort location K13622 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 353.0
TH1_k127_186478_5 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 341.0
TH1_k127_186478_6 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000238 208.0
TH1_k127_186478_7 HNH nucleases - - - 0.000000000000000000000000000000000000000008306 156.0
TH1_k127_186478_8 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000002672 158.0
TH1_k127_186478_9 protocatechuate 3,4-dioxygenase - - - 0.00000000000000000000000000000000000001498 150.0
TH1_k127_1880640_0 Tetratricopeptide repeat - - - 2.522e-196 644.0
TH1_k127_1880640_1 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 471.0
TH1_k127_1880640_2 Transcription termination factor nusG - - - 0.000000000000000000000000000000000000000000000000007045 185.0
TH1_k127_1880640_3 - - - - 0.000000000000000000000000000002683 123.0
TH1_k127_198096_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 307.0
TH1_k127_198096_1 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000009411 240.0
TH1_k127_198096_2 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.000000000004423 69.0
TH1_k127_198096_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000001672 61.0
TH1_k127_198258_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 293.0
TH1_k127_198258_1 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000008397 189.0
TH1_k127_198258_2 Cytochrome c3 - - - 0.0000000000000000000000005046 109.0
TH1_k127_198258_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000003147 104.0
TH1_k127_2036405_0 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 317.0
TH1_k127_2036405_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000006015 188.0
TH1_k127_2036405_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000508 181.0
TH1_k127_2036405_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000008123 128.0
TH1_k127_2052_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.726e-277 861.0
TH1_k127_2052_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.154e-195 616.0
TH1_k127_2052_10 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000239 119.0
TH1_k127_2052_11 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000003938 106.0
TH1_k127_2052_12 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.000000000000000000001004 98.0
TH1_k127_2052_13 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000001491 89.0
TH1_k127_2052_14 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000002781 64.0
TH1_k127_2052_2 Beta-eliminating lyase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 574.0
TH1_k127_2052_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 461.0
TH1_k127_2052_4 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001654 275.0
TH1_k127_2052_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000836 252.0
TH1_k127_2052_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000006188 242.0
TH1_k127_2052_7 NOG31153 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000001071 250.0
TH1_k127_2052_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000002705 231.0
TH1_k127_2052_9 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000006996 210.0
TH1_k127_207362_0 NADH ubiquinone oxidoreductase K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 9.974e-198 632.0
TH1_k127_207362_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 587.0
TH1_k127_207362_2 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 461.0
TH1_k127_207362_3 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 359.0
TH1_k127_207362_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000001572 167.0
TH1_k127_207362_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000001944 125.0
TH1_k127_207362_6 Cyclic nucleotide-monophosphate binding domain - - - 0.00000565 54.0
TH1_k127_213081_0 PFAM Radical SAM - - - 7.859e-211 666.0
TH1_k127_213081_1 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 311.0
TH1_k127_213081_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000002601 81.0
TH1_k127_213081_11 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000003316 75.0
TH1_k127_213081_12 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.000000000000521 79.0
TH1_k127_213081_14 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.000002453 53.0
TH1_k127_213081_2 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 301.0
TH1_k127_213081_3 TIGRFAM DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 286.0
TH1_k127_213081_4 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000001641 201.0
TH1_k127_213081_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000006108 164.0
TH1_k127_213081_6 Sulphur transport K07112 - - 0.000000000000000000000000000000000000003238 156.0
TH1_k127_213081_7 Sulphur transport K07112 - - 0.000000000000000000000000000000000001369 144.0
TH1_k127_213081_8 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000001252 126.0
TH1_k127_213081_9 RNase H - - - 0.00000000000000000000000004593 118.0
TH1_k127_2147640_0 electron transfer activity K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 390.0
TH1_k127_2147640_1 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 350.0
TH1_k127_2147640_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000004825 191.0
TH1_k127_2147640_3 YtkA-like - - - 0.00000000000000000000000000000003804 136.0
TH1_k127_2147640_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000009353 48.0
TH1_k127_219365_0 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 464.0
TH1_k127_219365_1 PFAM Response regulator receiver domain - - - 0.000000000000000000003713 98.0
TH1_k127_219365_2 - - - - 0.0000000000000000004013 89.0
TH1_k127_2274898_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 3.672e-228 724.0
TH1_k127_2274898_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 359.0
TH1_k127_2274898_10 - - - - 0.0000000000000000000000000008393 117.0
TH1_k127_2274898_11 PFAM von Willebrand factor type A K02448 - - 0.0000000000002624 70.0
TH1_k127_2274898_12 PFAM histidine kinase, HAMP region domain protein K03406 - - 0.00000000001555 66.0
TH1_k127_2274898_13 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.00000000003137 71.0
TH1_k127_2274898_14 - - - - 0.00004662 53.0
TH1_k127_2274898_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 338.0
TH1_k127_2274898_3 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 338.0
TH1_k127_2274898_4 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002102 273.0
TH1_k127_2274898_5 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002875 252.0
TH1_k127_2274898_6 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000001589 237.0
TH1_k127_2274898_7 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000000005325 195.0
TH1_k127_2274898_8 Glutathione peroxidase - - - 0.0000000000000000000000000000000000005839 145.0
TH1_k127_2274898_9 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000001352 141.0
TH1_k127_2311302_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 374.0
TH1_k127_2311302_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 300.0
TH1_k127_2311302_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001035 259.0
TH1_k127_2311302_3 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000003078 190.0
TH1_k127_2311302_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000007409 143.0
TH1_k127_2311302_5 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000001353 145.0
TH1_k127_2311302_6 Preprotein translocase SecG subunit K03075 - - 0.000000000000000002858 89.0
TH1_k127_2311302_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000007925 78.0
TH1_k127_23238_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 319.0
TH1_k127_23238_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 309.0
TH1_k127_23238_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000002265 169.0
TH1_k127_23238_3 XdhC Rossmann domain K07402 - - 0.0000000000000855 74.0
TH1_k127_2435933_0 Heat shock 70 kDa protein K04043 - - 1.181e-316 979.0
TH1_k127_2435933_1 Cytochrome c554 and c-prime - - - 6.274e-247 770.0
TH1_k127_2435933_10 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000002061 246.0
TH1_k127_2435933_11 Pfam:TPM K08988 - - 0.00000000000000000000000000000000000000000000000000000007926 205.0
TH1_k127_2435933_12 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000001694 179.0
TH1_k127_2435933_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000002478 154.0
TH1_k127_2435933_14 AI-2E family transporter - - - 0.00000000000000000000000000000000002861 148.0
TH1_k127_2435933_16 anti-sigma regulatory factor K04757 - 2.7.11.1 0.000000000000000000000131 102.0
TH1_k127_2435933_17 antisigma factor binding K04749 - - 0.0000000000000000001901 91.0
TH1_k127_2435933_18 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000009645 87.0
TH1_k127_2435933_19 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00007283 48.0
TH1_k127_2435933_2 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 490.0
TH1_k127_2435933_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 437.0
TH1_k127_2435933_4 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 432.0
TH1_k127_2435933_5 TrkA-N domain K03455,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 382.0
TH1_k127_2435933_6 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 291.0
TH1_k127_2435933_7 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 299.0
TH1_k127_2435933_8 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001116 273.0
TH1_k127_2435933_9 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000219 258.0
TH1_k127_2442141_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.283e-251 788.0
TH1_k127_2442141_1 ABC transporter K06158 - - 9.871e-235 741.0
TH1_k127_2442141_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 4.194e-222 713.0
TH1_k127_2442141_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 299.0
TH1_k127_2442141_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000429 232.0
TH1_k127_2442141_5 Rhodanese Homology Domain - - - 0.0000000000000001211 81.0
TH1_k127_2442141_6 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000129 73.0
TH1_k127_2456736_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 357.0
TH1_k127_2456736_1 SPTR Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000003323 160.0
TH1_k127_2456736_2 cheY-homologous receiver domain - - - 0.00000000000000000003076 96.0
TH1_k127_2456736_3 PAS domain - - - 0.00000008862 60.0
TH1_k127_2456736_4 PFAM CBS domain - - - 0.0000001336 57.0
TH1_k127_2456736_5 signal transduction protein - - - 0.00008191 48.0
TH1_k127_246108_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 501.0
TH1_k127_246108_1 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 309.0
TH1_k127_246108_2 methyltransferase - - - 0.000000000000000000000000000000000001162 147.0
TH1_k127_246108_3 Tetratricopeptide repeat - - - 0.000000000000001313 83.0
TH1_k127_246108_4 4Fe-4S binding domain - - - 0.000000000000001426 78.0
TH1_k127_246108_5 CYTH K05873 - 4.6.1.1 0.000000000001988 74.0
TH1_k127_246108_6 Cupin 2, conserved barrel domain protein - - - 0.000000000003827 70.0
TH1_k127_246159_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 9.617e-225 702.0
TH1_k127_246159_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 525.0
TH1_k127_246159_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000001051 244.0
TH1_k127_246159_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000007229 231.0
TH1_k127_2467465_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 5.898e-204 646.0
TH1_k127_2467465_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 580.0
TH1_k127_2467465_10 PFAM GGDEF domain containing protein K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000002287 188.0
TH1_k127_2467465_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000000000002109 173.0
TH1_k127_2467465_12 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000003786 166.0
TH1_k127_2467465_2 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 563.0
TH1_k127_2467465_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 549.0
TH1_k127_2467465_4 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 505.0
TH1_k127_2467465_5 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 373.0
TH1_k127_2467465_6 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 331.0
TH1_k127_2467465_7 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 323.0
TH1_k127_2467465_8 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000004826 213.0
TH1_k127_2467465_9 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000002206 198.0
TH1_k127_2470791_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 1.891e-289 911.0
TH1_k127_2470791_1 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 539.0
TH1_k127_2470791_10 Periplasmic or secreted lipoprotein K04065 - - 0.0000001406 57.0
TH1_k127_2470791_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 516.0
TH1_k127_2470791_3 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 364.0
TH1_k127_2470791_4 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 316.0
TH1_k127_2470791_5 Catalyzes the synthesis of activated sulfate K00860,K00958 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000007383 216.0
TH1_k127_2470791_6 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000001255 130.0
TH1_k127_2470791_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000001356 89.0
TH1_k127_2470791_8 Carboxymuconolactone decarboxylase family - - - 0.0000000003357 66.0
TH1_k127_2510589_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.552e-283 881.0
TH1_k127_2510589_1 Enoyl-(Acyl carrier protein) reductase - - - 4.555e-226 710.0
TH1_k127_2510589_10 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000001147 101.0
TH1_k127_2510589_12 Sporulation and spore germination - - - 0.00000000003204 71.0
TH1_k127_2510589_2 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 383.0
TH1_k127_2510589_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 356.0
TH1_k127_2510589_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 351.0
TH1_k127_2510589_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 322.0
TH1_k127_2510589_6 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 310.0
TH1_k127_2510589_7 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 336.0
TH1_k127_2510589_8 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000201 223.0
TH1_k127_2510589_9 PIN domain - - - 0.0000000000000000000000000000000001608 138.0
TH1_k127_2569315_0 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 432.0
TH1_k127_2569315_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000003364 111.0
TH1_k127_2640269_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 435.0
TH1_k127_2640269_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000001247 114.0
TH1_k127_2640269_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000007338 75.0
TH1_k127_2640269_3 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00003017 46.0
TH1_k127_2640571_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 607.0
TH1_k127_2640571_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 588.0
TH1_k127_2640571_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 316.0
TH1_k127_2640571_11 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 309.0
TH1_k127_2640571_12 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 297.0
TH1_k127_2640571_13 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 287.0
TH1_k127_2640571_14 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001179 281.0
TH1_k127_2640571_15 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000002753 248.0
TH1_k127_2640571_16 prephenate dehydrogenase K00220 - 1.3.1.12,1.3.1.43 0.000000000000000000000000000000000000000000000000000000000000000009302 234.0
TH1_k127_2640571_17 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0000000000000000000000000000000000000000000000000000000000000004016 244.0
TH1_k127_2640571_18 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000002617 207.0
TH1_k127_2640571_19 - - - - 0.000000000000000000000000000000000000000000000002167 183.0
TH1_k127_2640571_2 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 509.0
TH1_k127_2640571_20 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000001815 164.0
TH1_k127_2640571_21 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000003298 143.0
TH1_k127_2640571_22 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000006907 126.0
TH1_k127_2640571_23 PFAM RNA recognition motif - - - 0.000000000000000000000000009989 113.0
TH1_k127_2640571_24 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000007049 106.0
TH1_k127_2640571_25 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000001119 80.0
TH1_k127_2640571_26 - - - - 0.00000000000002372 81.0
TH1_k127_2640571_27 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000003877 74.0
TH1_k127_2640571_28 aspartic-type endopeptidase activity K06985 - - 0.000001637 59.0
TH1_k127_2640571_3 large subunit K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009446 499.0
TH1_k127_2640571_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 478.0
TH1_k127_2640571_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 473.0
TH1_k127_2640571_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 441.0
TH1_k127_2640571_7 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 426.0
TH1_k127_2640571_8 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 413.0
TH1_k127_2640571_9 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 356.0
TH1_k127_2656060_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 387.0
TH1_k127_2656060_1 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000002075 153.0
TH1_k127_2656060_2 - - - - 0.000000000000000000000000000000000001761 142.0
TH1_k127_2656060_4 Transposase and inactivated derivatives K07483 - - 0.00000000000000000000002622 102.0
TH1_k127_2656060_5 Belongs to the precorrin methyltransferase family K02303,K13542 - 2.1.1.107,4.2.1.75 0.000000004341 57.0
TH1_k127_2656060_6 PFAM Glycosyl transferase, group 1 - - - 0.0002677 44.0
TH1_k127_2684659_0 TRCF K03723 - - 3.021e-228 746.0
TH1_k127_2684659_1 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 571.0
TH1_k127_2684659_10 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 366.0
TH1_k127_2684659_11 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000238 274.0
TH1_k127_2684659_12 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003606 246.0
TH1_k127_2684659_13 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000003169 241.0
TH1_k127_2684659_14 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000008379 223.0
TH1_k127_2684659_15 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000002155 213.0
TH1_k127_2684659_16 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000002289 196.0
TH1_k127_2684659_17 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000009932 180.0
TH1_k127_2684659_18 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000000005397 170.0
TH1_k127_2684659_19 nucleotide metabolic process - - - 0.00000000000000000000000000000000000000003456 161.0
TH1_k127_2684659_2 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 573.0
TH1_k127_2684659_20 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000000000000003581 154.0
TH1_k127_2684659_21 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000003879 137.0
TH1_k127_2684659_22 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000001084 139.0
TH1_k127_2684659_23 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000002254 124.0
TH1_k127_2684659_24 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000002263 132.0
TH1_k127_2684659_25 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000004738 110.0
TH1_k127_2684659_26 cAMP biosynthetic process - - - 0.0000000004429 72.0
TH1_k127_2684659_27 - - - - 0.0000931 46.0
TH1_k127_2684659_28 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.0009065 44.0
TH1_k127_2684659_3 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 552.0
TH1_k127_2684659_4 Chromate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 473.0
TH1_k127_2684659_5 PAS domain K09155 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 466.0
TH1_k127_2684659_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 435.0
TH1_k127_2684659_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 426.0
TH1_k127_2684659_8 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 406.0
TH1_k127_2684659_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 366.0
TH1_k127_2752299_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 468.0
TH1_k127_2752299_1 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000002109 173.0
TH1_k127_2752299_2 DSBA-like thioredoxin domain - - - 0.0005067 45.0
TH1_k127_2797892_0 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 430.0
TH1_k127_2797892_1 Ubiquinol--cytochrome c reductase - - - 0.00000000000000000000000000000000000000000000003148 172.0
TH1_k127_2797892_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000001486 114.0
TH1_k127_2840692_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 585.0
TH1_k127_2862238_0 DHHA2 domain K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 551.0
TH1_k127_2862238_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 469.0
TH1_k127_2862238_2 PFAM Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 347.0
TH1_k127_2871056_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1090.0
TH1_k127_2871056_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 356.0
TH1_k127_2991607_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.601e-225 704.0
TH1_k127_2991607_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 8.699e-218 685.0
TH1_k127_2991607_10 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000000000000000000000001067 178.0
TH1_k127_2991607_11 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000001441 179.0
TH1_k127_2991607_12 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000007024 144.0
TH1_k127_2991607_13 Chromate K07240 - - 0.0000000000000000000000000000005228 133.0
TH1_k127_2991607_14 Chromate transporter K07240 - - 0.0000000000000000000000000000019 127.0
TH1_k127_2991607_15 - - - - 0.0000000000000000000000001587 108.0
TH1_k127_2991607_16 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000002818 93.0
TH1_k127_2991607_17 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 0.00000006702 61.0
TH1_k127_2991607_2 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 503.0
TH1_k127_2991607_3 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 375.0
TH1_k127_2991607_4 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 363.0
TH1_k127_2991607_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 308.0
TH1_k127_2991607_6 B12 binding domain K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 312.0
TH1_k127_2991607_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
TH1_k127_2991607_8 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004577 251.0
TH1_k127_2991607_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000003027 239.0
TH1_k127_3015804_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.561e-242 758.0
TH1_k127_3015804_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 580.0
TH1_k127_3015804_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001117 289.0
TH1_k127_3015804_11 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003281 288.0
TH1_k127_3015804_12 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000003782 224.0
TH1_k127_3015804_13 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000004487 222.0
TH1_k127_3015804_14 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000004754 175.0
TH1_k127_3015804_17 - - - - 0.0000001558 56.0
TH1_k127_3015804_18 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00008369 49.0
TH1_k127_3015804_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 561.0
TH1_k127_3015804_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 493.0
TH1_k127_3015804_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 489.0
TH1_k127_3015804_5 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 456.0
TH1_k127_3015804_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 385.0
TH1_k127_3015804_7 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 392.0
TH1_k127_3015804_8 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 310.0
TH1_k127_3015804_9 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008306 286.0
TH1_k127_3070734_0 PFAM ferredoxin-dependent glutamate synthase - - - 3.893e-236 734.0
TH1_k127_3070734_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 419.0
TH1_k127_3070734_2 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 340.0
TH1_k127_3070734_3 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001319 265.0
TH1_k127_3070734_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000003036 94.0
TH1_k127_309673_0 Seven times multi-haem cytochrome CxxCH - - - 3.048e-198 624.0
TH1_k127_309673_1 - - - - 0.00000000000000000000000000000000000000000000000000000000002765 213.0
TH1_k127_309673_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000002977 160.0
TH1_k127_309673_3 Prokaryotic cytochrome b561 - - - 0.00000006228 54.0
TH1_k127_309684_0 - - - - 0.0000000000000000000000000000000000000000000000000000000004822 208.0
TH1_k127_309684_1 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000001564 164.0
TH1_k127_309684_2 - - - - 0.0000000000000000000000000000000000464 137.0
TH1_k127_309684_3 MOSC domain - - - 0.00000000000000001564 84.0
TH1_k127_309684_4 Prokaryotic cytochrome b561 - - - 0.00000006228 54.0
TH1_k127_3155579_0 40-residue yvtn family beta-propeller repeat protein - - - 4.061e-211 664.0
TH1_k127_3155579_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 424.0
TH1_k127_3155579_10 PFAM response regulator receiver - - - 0.00001578 52.0
TH1_k127_3155579_2 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 359.0
TH1_k127_3155579_3 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 317.0
TH1_k127_3155579_4 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 333.0
TH1_k127_3155579_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001433 286.0
TH1_k127_3155579_6 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001133 263.0
TH1_k127_3155579_7 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000002261 164.0
TH1_k127_3155579_8 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000103 151.0
TH1_k127_3155579_9 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000973 121.0
TH1_k127_3169253_0 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 409.0
TH1_k127_3169253_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000001557 245.0
TH1_k127_3169253_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000001994 203.0
TH1_k127_3169253_3 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000002755 195.0
TH1_k127_3169253_4 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847 - 5.4.99.2 0.00000000000000000000000000000000000000000000001629 171.0
TH1_k127_3169253_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000123 152.0
TH1_k127_3169253_6 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000000000000001655 153.0
TH1_k127_3169253_7 Sulfurtransferase TusA - - - 0.00000000000000000000000002303 109.0
TH1_k127_3169253_8 - - - - 0.00004313 48.0
TH1_k127_3225178_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.82e-218 695.0
TH1_k127_3225178_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 446.0
TH1_k127_3225178_10 - - - - 0.000000000000000000000000000000000003001 139.0
TH1_k127_3225178_11 B12 binding domain K04034 - 1.21.98.3 0.000000000000000000004658 97.0
TH1_k127_3225178_12 - - - - 0.0000000000001016 75.0
TH1_k127_3225178_13 PFAM Nitrate reductase gamma subunit - - - 0.000000003273 66.0
TH1_k127_3225178_2 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 344.0
TH1_k127_3225178_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 328.0
TH1_k127_3225178_4 PFAM HhH-GPD family protein K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 298.0
TH1_k127_3225178_5 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000032 293.0
TH1_k127_3225178_6 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000004299 236.0
TH1_k127_3225178_7 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000001794 236.0
TH1_k127_3225178_8 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000004576 180.0
TH1_k127_3225178_9 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000000000001631 148.0
TH1_k127_3277812_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.302e-264 830.0
TH1_k127_3277812_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.402e-211 670.0
TH1_k127_3277812_2 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 454.0
TH1_k127_3277812_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 344.0
TH1_k127_3277812_4 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000002584 132.0
TH1_k127_3277812_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000015 98.0
TH1_k127_3277812_6 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001222 72.0
TH1_k127_3277812_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000001665 77.0
TH1_k127_3277812_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00007105 46.0
TH1_k127_32885_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 570.0
TH1_k127_3379516_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.469e-274 861.0
TH1_k127_3379516_1 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 4.756e-223 703.0
TH1_k127_3379516_2 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 547.0
TH1_k127_3379516_3 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 487.0
TH1_k127_3379516_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000272 245.0
TH1_k127_3379516_5 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000001994 185.0
TH1_k127_3394416_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 2.264e-232 722.0
TH1_k127_3394416_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 331.0
TH1_k127_3394416_2 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 301.0
TH1_k127_3394416_3 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000003106 248.0
TH1_k127_3394416_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000001698 206.0
TH1_k127_3394416_5 RDD family - - - 0.00000000000000000000000000004098 121.0
TH1_k127_34139_0 surface antigen variable number repeat protein K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 554.0
TH1_k127_34139_1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 405.0
TH1_k127_34139_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000007103 251.0
TH1_k127_34139_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000004379 200.0
TH1_k127_34139_4 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000001511 161.0
TH1_k127_34139_6 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000002091 60.0
TH1_k127_34139_7 - - - - 0.000002045 57.0
TH1_k127_3515237_0 Surface antigen K07277 - - 1.832e-248 789.0
TH1_k127_3515237_1 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 1.259e-194 616.0
TH1_k127_3515237_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00000000000000000000000000000000008577 139.0
TH1_k127_3515237_2 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 595.0
TH1_k127_3515237_3 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 552.0
TH1_k127_3515237_4 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 551.0
TH1_k127_3515237_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 385.0
TH1_k127_3515237_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 364.0
TH1_k127_3515237_7 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 283.0
TH1_k127_3515237_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000004643 193.0
TH1_k127_3515237_9 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000001719 155.0
TH1_k127_369686_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 566.0
TH1_k127_369686_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 467.0
TH1_k127_369686_10 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.00000000000000001749 86.0
TH1_k127_369686_11 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000388 79.0
TH1_k127_369686_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 316.0
TH1_k127_369686_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002364 273.0
TH1_k127_369686_4 PHP-associated K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000004504 229.0
TH1_k127_369686_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000002064 184.0
TH1_k127_369686_6 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.000000000000000000000000000000000000004269 151.0
TH1_k127_369686_7 DRTGG domain - - - 0.00000000000000000000000000000001312 129.0
TH1_k127_369686_8 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000188 106.0
TH1_k127_369686_9 PFAM DRTGG domain - - - 0.000000000000000000000001297 110.0
TH1_k127_3738340_0 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 398.0
TH1_k127_3738340_1 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000003508 258.0
TH1_k127_3738340_2 COG3267 Type II secretory pathway, component ExeA K02450 - - 0.0000000007886 59.0
TH1_k127_3758467_0 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000009374 131.0
TH1_k127_3758467_1 Subtilase family - - - 0.0000000000000000000000008886 111.0
TH1_k127_3758956_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 568.0
TH1_k127_3758956_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 310.0
TH1_k127_3758956_2 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003379 239.0
TH1_k127_3758956_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000001751 122.0
TH1_k127_3758956_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000007311 121.0
TH1_k127_376853_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009904 276.0
TH1_k127_376853_1 - - - - 0.000000000000000000000000000000000000000000000001752 176.0
TH1_k127_376853_2 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.0000000000000000000158 96.0
TH1_k127_376853_3 - - - - 0.0000001103 57.0
TH1_k127_3829113_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 465.0
TH1_k127_3829113_1 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000001458 174.0
TH1_k127_3829113_2 Protein required for attachment to host cells - - - 0.00000000000000000000000000000006879 129.0
TH1_k127_3829113_3 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000001412 66.0
TH1_k127_3829113_4 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00006381 46.0
TH1_k127_3850606_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 1.001e-261 826.0
TH1_k127_3850606_1 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 308.0
TH1_k127_3850606_2 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 287.0
TH1_k127_3850606_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000001297 136.0
TH1_k127_3850606_4 Mo-molybdopterin cofactor biosynthetic process - - - 0.00000000000004475 73.0
TH1_k127_3850606_5 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00000000007224 71.0
TH1_k127_3943064_0 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000001648 128.0
TH1_k127_3943064_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K12339 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000001892 85.0
TH1_k127_3943064_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01697 GO:0000096,GO:0000097,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004122,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007089,GO:0007346,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009092,GO:0009403,GO:0009404,GO:0009987,GO:0010494,GO:0010564,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019343,GO:0019344,GO:0019346,GO:0019748,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0035770,GO:0036094,GO:0036464,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0045787,GO:0045931,GO:0046394,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050667,GO:0050789,GO:0050794,GO:0051726,GO:0065007,GO:0070279,GO:0070813,GO:0070814,GO:0071704,GO:0090068,GO:0097159,GO:1900087,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902806,GO:1902808,GO:1990904,GO:2000045 4.2.1.22 0.0000000000284 66.0
TH1_k127_3943064_4 PilZ domain K02676 - - 0.0000000007049 66.0
TH1_k127_3943064_5 Recombination protein O C terminal K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00002035 53.0
TH1_k127_3943064_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01883,K12339 - 2.5.1.47,6.1.1.16 0.00002278 48.0
TH1_k127_396125_0 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 579.0
TH1_k127_396125_1 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 316.0
TH1_k127_396125_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002776 256.0
TH1_k127_396125_3 protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000000001127 185.0
TH1_k127_3974365_0 Cytochrome C and Quinol oxidase polypeptide I K04561 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 410.0
TH1_k127_3974365_1 PFAM Cytochrome b5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 298.0
TH1_k127_3974365_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000008182 191.0
TH1_k127_3974365_3 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000005198 151.0
TH1_k127_3974365_4 4Fe-4S binding domain - - - 0.000008926 51.0
TH1_k127_397707_0 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000092 290.0
TH1_k127_397707_1 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002314 285.0
TH1_k127_397707_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000001139 87.0
TH1_k127_397707_3 - - - - 0.0000000000000001364 88.0
TH1_k127_397707_5 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.00000000004609 76.0
TH1_k127_397707_6 Prokaryotic N-terminal methylation motif - - - 0.00000003778 56.0
TH1_k127_398552_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 331.0
TH1_k127_398552_1 PFAM MscS Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 290.0
TH1_k127_398552_2 Protein involved in outer membrane biogenesis K07289,K09800 - - 0.00000000000000000000000000000000000000000000007428 195.0
TH1_k127_398552_3 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000000001909 171.0
TH1_k127_4004744_0 Aminotransferase class-III K01845 - 5.4.3.8 3.465e-198 625.0
TH1_k127_4004744_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 538.0
TH1_k127_4004744_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000001436 201.0
TH1_k127_4004744_3 response regulator receiver - - - 0.000000000000000000000000000000000000000001513 158.0
TH1_k127_4004744_4 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000003653 129.0
TH1_k127_4004744_5 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000989 92.0
TH1_k127_4029268_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 1.877e-204 641.0
TH1_k127_4029268_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 557.0
TH1_k127_4029268_10 SMART helix-turn-helix domain protein K15539 - - 0.00000000003305 73.0
TH1_k127_4029268_11 DnaJ-class molecular chaperone with C-terminal Zn finger domain - - - 0.00000000976 68.0
TH1_k127_4029268_2 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 540.0
TH1_k127_4029268_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 491.0
TH1_k127_4029268_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 386.0
TH1_k127_4029268_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 328.0
TH1_k127_4029268_6 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000002193 236.0
TH1_k127_4029268_7 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000004505 210.0
TH1_k127_4029268_8 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000007044 181.0
TH1_k127_4029268_9 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000003052 79.0
TH1_k127_4111752_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 3.552e-289 903.0
TH1_k127_4111752_1 Cache_2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 412.0
TH1_k127_4111752_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 368.0
TH1_k127_4111752_3 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000000000000000000000000574 117.0
TH1_k127_4111752_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000001856 112.0
TH1_k127_4182973_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1299.0
TH1_k127_4182973_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1014.0
TH1_k127_4182973_10 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000001134 210.0
TH1_k127_4182973_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000003204 187.0
TH1_k127_4182973_12 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000005153 181.0
TH1_k127_4182973_13 metalloendopeptidase activity K03799 - - 0.00000000000000000000000000000000000000001377 170.0
TH1_k127_4182973_14 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000004296 147.0
TH1_k127_4182973_15 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000000000006561 135.0
TH1_k127_4182973_16 peroxiredoxin activity - - - 0.000000000000000000000000000004374 125.0
TH1_k127_4182973_17 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000023 115.0
TH1_k127_4182973_18 PFAM amidohydrolase - - - 0.000000000000000000000000002253 124.0
TH1_k127_4182973_19 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000002864 108.0
TH1_k127_4182973_2 Molecular chaperone. Has ATPase activity K04079 - - 2.601e-286 891.0
TH1_k127_4182973_20 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000007049 106.0
TH1_k127_4182973_21 PFAM Rubredoxin-type Fe(Cys)4 protein K05297 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592 1.18.1.1 0.0000000000000000000001197 97.0
TH1_k127_4182973_22 NusG domain II K00805 - 2.5.1.30 0.0000000000000000004866 91.0
TH1_k127_4182973_23 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000001013 87.0
TH1_k127_4182973_24 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000007097 73.0
TH1_k127_4182973_25 - - - - 0.0000000000004809 71.0
TH1_k127_4182973_26 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000006308 70.0
TH1_k127_4182973_27 Glutaredoxin - - - 0.000001183 52.0
TH1_k127_4182973_28 PFAM Rhodanese domain protein - - - 0.000002092 49.0
TH1_k127_4182973_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 369.0
TH1_k127_4182973_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 362.0
TH1_k127_4182973_5 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 340.0
TH1_k127_4182973_6 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 346.0
TH1_k127_4182973_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 290.0
TH1_k127_4182973_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000002819 259.0
TH1_k127_4182973_9 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000008539 244.0
TH1_k127_4256124_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 7.502e-277 875.0
TH1_k127_4256124_1 Glycosyl hydrolase family 57 - - - 6.717e-238 757.0
TH1_k127_4256124_10 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000005967 179.0
TH1_k127_4256124_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000001313 163.0
TH1_k127_4256124_12 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000001609 153.0
TH1_k127_4256124_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000006403 132.0
TH1_k127_4256124_14 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000001947 121.0
TH1_k127_4256124_15 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000002159 113.0
TH1_k127_4256124_16 - - - - 0.00000000000000000000002187 114.0
TH1_k127_4256124_17 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000004599 96.0
TH1_k127_4256124_18 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000005855 85.0
TH1_k127_4256124_19 cell cycle K05589,K12065,K13052 - - 0.00000000000001189 77.0
TH1_k127_4256124_2 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 584.0
TH1_k127_4256124_20 Pfam SNARE associated Golgi protein - - - 0.0000000000004701 70.0
TH1_k127_4256124_3 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 463.0
TH1_k127_4256124_4 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 449.0
TH1_k127_4256124_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 421.0
TH1_k127_4256124_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 411.0
TH1_k127_4256124_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 384.0
TH1_k127_4256124_8 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 329.0
TH1_k127_4256124_9 - K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000001129 211.0
TH1_k127_426225_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 3.5e-323 1003.0
TH1_k127_426225_1 FAD dependent oxidoreductase K16885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 578.0
TH1_k127_426225_2 4Fe-4S dicluster domain K16887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 389.0
TH1_k127_426225_3 FAD binding domain K00394 - 1.8.99.2 0.0000000000000000000000000000000000000003262 150.0
TH1_k127_4426985_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 497.0
TH1_k127_4426985_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 422.0
TH1_k127_4426985_2 sulfur carrier activity - - - 0.0000000000000000000000000000000000000000003745 160.0
TH1_k127_4426985_3 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000003941 122.0
TH1_k127_4426985_4 Competence protein K02238 - - 0.000000000000000000000001126 109.0
TH1_k127_4426985_5 Sulfotransferase domain - - - 0.0002145 49.0
TH1_k127_4431326_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 6.595e-246 781.0
TH1_k127_4562823_0 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000000000000002821 222.0
TH1_k127_4562823_1 - - - - 0.0000000000004801 72.0
TH1_k127_458420_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 406.0
TH1_k127_458420_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 352.0
TH1_k127_458420_10 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000002856 159.0
TH1_k127_458420_11 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000001373 148.0
TH1_k127_458420_12 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000002329 149.0
TH1_k127_458420_13 Domain of unknown function (DUF4388) - - - 0.00000000000000000000003264 114.0
TH1_k127_458420_14 DnaJ molecular chaperone homology domain - - - 0.0000000002723 73.0
TH1_k127_458420_15 TonB C terminal K03832 - - 0.000005196 57.0
TH1_k127_458420_2 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 334.0
TH1_k127_458420_3 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 327.0
TH1_k127_458420_4 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 295.0
TH1_k127_458420_5 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008793 265.0
TH1_k127_458420_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000006045 246.0
TH1_k127_458420_7 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000009572 225.0
TH1_k127_458420_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000008036 205.0
TH1_k127_458420_9 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000003228 197.0
TH1_k127_4617390_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 482.0
TH1_k127_4617390_1 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 303.0
TH1_k127_4617390_2 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000262 270.0
TH1_k127_4617390_3 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000593 237.0
TH1_k127_4617390_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000005367 208.0
TH1_k127_4617390_5 - - - - 0.0000002052 55.0
TH1_k127_4617390_6 - - - - 0.000007312 51.0
TH1_k127_4644_0 Elongation factor G, domain IV K02355 - - 5.407e-291 908.0
TH1_k127_4644_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.501e-244 765.0
TH1_k127_4644_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000004239 142.0
TH1_k127_4644_11 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000000000003046 117.0
TH1_k127_4644_12 Cold shock K03704 - - 0.000000000000000000000000271 106.0
TH1_k127_4644_13 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.0000000000000000000001158 99.0
TH1_k127_4644_14 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000003241 101.0
TH1_k127_4644_15 - - - - 0.0000000000000000000009324 97.0
TH1_k127_4644_16 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000004672 91.0
TH1_k127_4644_17 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.0000000005747 64.0
TH1_k127_4644_18 - - - - 0.000000002233 64.0
TH1_k127_4644_19 PFAM NAD-dependent epimerase dehydratase - - - 0.00001324 50.0
TH1_k127_4644_2 DNA photolyase K01669 - 4.1.99.3 3.924e-196 621.0
TH1_k127_4644_3 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 606.0
TH1_k127_4644_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000001077 242.0
TH1_k127_4644_5 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000001605 190.0
TH1_k127_4644_6 PFAM pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000000000000000009265 163.0
TH1_k127_4644_7 Cytochrome P460 - - - 0.000000000000000000000000000000000000000007147 160.0
TH1_k127_4644_8 ferredoxin-thioredoxin reductase activity - - - 0.000000000000000000000000000000000000003219 148.0
TH1_k127_4644_9 methyltransferase activity - - - 0.00000000000000000000000000000000000009236 149.0
TH1_k127_4871777_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5.879e-310 965.0
TH1_k127_4871777_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.959e-285 885.0
TH1_k127_4871777_2 Dehydratase family K01687 - 4.2.1.9 1.476e-258 807.0
TH1_k127_4871777_3 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000007626 257.0
TH1_k127_4871777_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000006943 138.0
TH1_k127_4871777_5 Ubiquinol--cytochrome c reductase - - - 0.00000000000000000000000000006933 116.0
TH1_k127_4871777_6 Transcriptional regulator - - - 0.0000000000000000000001613 101.0
TH1_k127_4871777_7 - - - - 0.00000000000000002915 85.0
TH1_k127_4871777_8 Evidence 4 Homologs of previously reported genes of - - - 0.00000000001338 68.0
TH1_k127_490675_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.362e-317 998.0
TH1_k127_490675_1 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 380.0
TH1_k127_490675_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000244 269.0
TH1_k127_490675_3 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000005843 155.0
TH1_k127_490675_4 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000002294 152.0
TH1_k127_490675_5 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.000000001508 65.0
TH1_k127_490675_6 Prokaryotic N-terminal methylation motif K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000446 57.0
TH1_k127_4937933_0 Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid K00627,K05714,K10216,K10222,K10623 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0018771,GO:0019439,GO:0019622,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046164,GO:0046395,GO:0046435,GO:0052823,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 2.3.1.12,3.7.1.14,3.7.1.8,3.7.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 316.0
TH1_k127_4937933_1 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002484 271.0
TH1_k127_4954397_0 metal ion transmembrane transporter activity K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 560.0
TH1_k127_4954397_1 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 568.0
TH1_k127_4954397_3 Glutamine amidotransferase class-I - - - 0.0000000001753 64.0
TH1_k127_4954397_4 electron transfer activity K05337,K17247 - - 0.0000005097 53.0
TH1_k127_4955609_0 glycolate transport K14393 - - 1.848e-257 810.0
TH1_k127_4955609_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 443.0
TH1_k127_4955609_2 membrane - - - 0.0000000000000000000004137 98.0
TH1_k127_4955609_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000002807 51.0
TH1_k127_4961877_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 5.929e-288 896.0
TH1_k127_4961877_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 379.0
TH1_k127_4961877_2 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000002167 231.0
TH1_k127_4961877_3 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000007461 203.0
TH1_k127_4961877_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000004252 204.0
TH1_k127_4961877_5 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000001731 182.0
TH1_k127_4961877_6 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000481 160.0
TH1_k127_4961877_7 Predicted membrane protein (DUF2207) - - - 0.0000004544 54.0
TH1_k127_4963695_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 486.0
TH1_k127_4963695_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001688 283.0
TH1_k127_4969744_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1497.0
TH1_k127_4969744_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.305e-263 830.0
TH1_k127_4969744_10 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000003056 160.0
TH1_k127_4969744_11 cytochrome complex assembly - - - 0.000000000000000000000000000000003114 130.0
TH1_k127_4969744_12 acetyltransferase - - - 0.00000000000000000000000000000005607 134.0
TH1_k127_4969744_13 methyltransferase K05928 - 2.1.1.95 0.0000000000000000000001802 105.0
TH1_k127_4969744_14 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000003501 66.0
TH1_k127_4969744_15 Belongs to the N-Me-Phe pilin family K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000001407 60.0
TH1_k127_4969744_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 430.0
TH1_k127_4969744_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 425.0
TH1_k127_4969744_4 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 306.0
TH1_k127_4969744_5 PFAM Glycosyl transferase family 2 K20534 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002251 278.0
TH1_k127_4969744_6 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003019 244.0
TH1_k127_4969744_7 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000007268 210.0
TH1_k127_4969744_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000003725 202.0
TH1_k127_4969744_9 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000442 156.0
TH1_k127_4975021_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 499.0
TH1_k127_4975021_1 Pas domain - - - 0.0000000000000000000000000000000000000000000004014 192.0
TH1_k127_4975021_2 VanZ like family - - - 0.000000000000000000000000000000000000002289 156.0
TH1_k127_4980880_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 481.0
TH1_k127_4980880_1 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000002475 232.0
TH1_k127_4980880_2 Transposase DDE domain - - - 0.000000000000000000000000000000000000006486 147.0
TH1_k127_4980880_3 Virulence protein RhuM family - - - 0.000000000000000000000000000002939 122.0
TH1_k127_4980880_4 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000007332 113.0
TH1_k127_4980880_5 Nad-dependent epimerase dehydratase K00091,K01784 - 1.1.1.219,5.1.3.2 0.00000000000000000000004934 110.0
TH1_k127_4980880_6 DDE superfamily endonuclease K07494 - - 0.0000000000000000007244 91.0
TH1_k127_4980880_7 PglZ domain - - - 0.000000000003247 70.0
TH1_k127_5000224_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 502.0
TH1_k127_5000224_1 ABC transporter (Permease K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 355.0
TH1_k127_5000224_2 ABC transporter permease K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 343.0
TH1_k127_5000224_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002657 248.0
TH1_k127_5000224_4 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000216 123.0
TH1_k127_5000224_5 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000001234 109.0
TH1_k127_5000224_6 - - - - 0.0006089 44.0
TH1_k127_5014635_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1224.0
TH1_k127_5014635_1 Ftsk_gamma K03466 - - 2.404e-199 644.0
TH1_k127_5014635_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 403.0
TH1_k127_5014635_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 285.0
TH1_k127_5014635_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000001507 144.0
TH1_k127_5014635_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000001814 134.0
TH1_k127_5014635_6 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000002484 138.0
TH1_k127_5029244_0 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000002469 134.0
TH1_k127_5029244_1 - - - - 0.00000000000000000000000000004269 122.0
TH1_k127_5029244_2 Transcriptional regulator - - - 0.0000000000000000000000001643 109.0
TH1_k127_5033260_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 553.0
TH1_k127_5033260_1 COG0463 Glycosyltransferases involved in cell wall biogenesis K13002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003886 256.0
TH1_k127_5033260_3 VanZ like family - - - 0.00000000000000001542 89.0
TH1_k127_5051836_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.001e-282 883.0
TH1_k127_5051836_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.255e-278 867.0
TH1_k127_5051836_10 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 364.0
TH1_k127_5051836_11 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 364.0
TH1_k127_5051836_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 354.0
TH1_k127_5051836_13 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 347.0
TH1_k127_5051836_14 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 324.0
TH1_k127_5051836_15 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 329.0
TH1_k127_5051836_16 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 319.0
TH1_k127_5051836_17 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 312.0
TH1_k127_5051836_18 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 295.0
TH1_k127_5051836_19 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 295.0
TH1_k127_5051836_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 606.0
TH1_k127_5051836_20 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001261 278.0
TH1_k127_5051836_21 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000004015 267.0
TH1_k127_5051836_22 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004477 268.0
TH1_k127_5051836_23 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000438 250.0
TH1_k127_5051836_24 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000004531 248.0
TH1_k127_5051836_25 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003616 253.0
TH1_k127_5051836_26 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000001363 226.0
TH1_k127_5051836_27 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000002921 218.0
TH1_k127_5051836_28 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000001225 210.0
TH1_k127_5051836_29 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000004314 211.0
TH1_k127_5051836_3 B3/4 domain K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 571.0
TH1_k127_5051836_30 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000000000000000000000000000000003346 210.0
TH1_k127_5051836_31 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000008951 199.0
TH1_k127_5051836_32 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000007603 193.0
TH1_k127_5051836_33 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000004139 196.0
TH1_k127_5051836_34 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000364 187.0
TH1_k127_5051836_35 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000216 181.0
TH1_k127_5051836_36 KR domain - - - 0.0000000000000000000000000000000000000000000004052 177.0
TH1_k127_5051836_37 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000005159 169.0
TH1_k127_5051836_38 - - - - 0.000000000000000000000000000000000000000000004476 173.0
TH1_k127_5051836_39 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000001241 169.0
TH1_k127_5051836_4 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 523.0
TH1_k127_5051836_40 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000001066 163.0
TH1_k127_5051836_41 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000002153 144.0
TH1_k127_5051836_42 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.000000000000000000000000000000000000436 156.0
TH1_k127_5051836_43 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000005962 134.0
TH1_k127_5051836_44 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000005964 129.0
TH1_k127_5051836_45 OstA-like protein K09774 - - 0.00000000000000000000000000000001414 132.0
TH1_k127_5051836_46 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.0000000000000000000000000000001667 130.0
TH1_k127_5051836_47 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000007928 117.0
TH1_k127_5051836_48 JAB/MPN domain - - - 0.0000000000000000000000000002316 120.0
TH1_k127_5051836_49 FabA-like domain K02372 - 4.2.1.59 0.00000000000000000000002722 104.0
TH1_k127_5051836_5 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 492.0
TH1_k127_5051836_50 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000007406 100.0
TH1_k127_5051836_51 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001129 93.0
TH1_k127_5051836_52 EamA-like transporter family - - - 0.0000000000000000000222 101.0
TH1_k127_5051836_53 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000008654 88.0
TH1_k127_5051836_54 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000003408 93.0
TH1_k127_5051836_55 Phosphopantetheine attachment site - - - 0.000000000000000007528 91.0
TH1_k127_5051836_56 - - - - 0.0000000000000000114 85.0
TH1_k127_5051836_57 - - - - 0.0000000000000002912 88.0
TH1_k127_5051836_58 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000008845 77.0
TH1_k127_5051836_59 Heavy-metal-associated domain K07213 - - 0.000000001694 61.0
TH1_k127_5051836_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 476.0
TH1_k127_5051836_60 PFAM Uncharacterised protein family UPF0150 - - - 0.000000002291 59.0
TH1_k127_5051836_61 PFAM Transposase, IS4-like - - - 0.0000001226 54.0
TH1_k127_5051836_62 PilZ domain - - - 0.0000008032 55.0
TH1_k127_5051836_63 - - - - 0.00001094 49.0
TH1_k127_5051836_64 Lipopolysaccharide-assembly, LptC-related - - - 0.00001999 53.0
TH1_k127_5051836_65 transposase activity - - - 0.0001011 44.0
TH1_k127_5051836_7 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 452.0
TH1_k127_5051836_8 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 445.0
TH1_k127_5051836_9 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 419.0
TH1_k127_5061637_0 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 519.0
TH1_k127_5061637_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 376.0
TH1_k127_5061637_2 Domain of Unknown Function (DUF748) - - - 0.00000000000004433 77.0
TH1_k127_5061637_3 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000003359 67.0
TH1_k127_5149913_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1153.0
TH1_k127_5149913_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 367.0
TH1_k127_5149913_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 362.0
TH1_k127_5149913_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000007918 225.0
TH1_k127_5149913_4 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000206 81.0
TH1_k127_5150818_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 459.0
TH1_k127_5150818_1 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 321.0
TH1_k127_5150818_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 313.0
TH1_k127_5150818_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 287.0
TH1_k127_5150818_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000003286 237.0
TH1_k127_5150818_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000225 223.0
TH1_k127_5150818_6 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000000000007621 152.0
TH1_k127_5150818_7 MlaD protein K02067 - - 0.0000000000000000000000001033 117.0
TH1_k127_5150818_8 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000118 84.0
TH1_k127_5177334_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.122e-198 641.0
TH1_k127_5177334_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 532.0
TH1_k127_5177334_10 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000001484 222.0
TH1_k127_5177334_11 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000003834 206.0
TH1_k127_5177334_12 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000009719 194.0
TH1_k127_5177334_13 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000011 168.0
TH1_k127_5177334_14 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000188 156.0
TH1_k127_5177334_15 nucleotidyltransferase activity K07075 - - 0.000000000000000000000000007887 120.0
TH1_k127_5177334_16 - - - - 0.0000000000000000005499 91.0
TH1_k127_5177334_17 Domain of unknown function (DUF1858) - - - 0.00000000000000002447 83.0
TH1_k127_5177334_18 - - - - 0.0000000000000965 79.0
TH1_k127_5177334_19 Sulfurtransferase TusA - - - 0.0000000006782 63.0
TH1_k127_5177334_2 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 522.0
TH1_k127_5177334_21 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000101 54.0
TH1_k127_5177334_3 binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 417.0
TH1_k127_5177334_4 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 355.0
TH1_k127_5177334_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 355.0
TH1_k127_5177334_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 311.0
TH1_k127_5177334_7 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000007622 251.0
TH1_k127_5177334_8 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000002098 236.0
TH1_k127_5177334_9 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002872 237.0
TH1_k127_5196444_0 Cytochrome c554 and c-prime - - - 4.472e-225 704.0
TH1_k127_5196444_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 469.0
TH1_k127_5196444_3 - - - - 0.00000000127 63.0
TH1_k127_5241419_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 533.0
TH1_k127_5241419_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 396.0
TH1_k127_5241419_2 Histidine kinase K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001025 284.0
TH1_k127_5241419_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000001091 212.0
TH1_k127_5241419_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000003716 152.0
TH1_k127_5241419_5 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000007971 119.0
TH1_k127_5241419_6 TQO small subunit DoxD K15977 - - 0.000000000000000000008822 97.0
TH1_k127_5241419_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001312 95.0
TH1_k127_5259774_0 ATPase (AAA superfamily K07133 - - 2.64e-207 651.0
TH1_k127_5259774_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 390.0
TH1_k127_5259774_2 PIN domain K07063 - - 0.0000000000000000000000000000000000001641 145.0
TH1_k127_5259774_3 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000005546 136.0
TH1_k127_5259774_4 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000006371 140.0
TH1_k127_5259774_5 4Fe-4S ferredoxin K00184 - - 0.000000000000000000000000000005871 126.0
TH1_k127_5259774_6 sequence-specific DNA binding - - - 0.0000000000000000000000000001781 116.0
TH1_k127_5259774_7 membrane K09790 - - 0.000000000000000000007593 96.0
TH1_k127_5259774_8 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000000000000001204 90.0
TH1_k127_5259774_9 Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor K03533 - - 0.00002982 53.0
TH1_k127_5309187_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1223.0
TH1_k127_5309187_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.861e-272 850.0
TH1_k127_5309187_10 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.000000000000000000000000000000000000001003 153.0
TH1_k127_5309187_11 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000006095 139.0
TH1_k127_5309187_12 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000004786 135.0
TH1_k127_5309187_13 nucleotidyltransferase activity - - - 0.00000000000000000000007784 104.0
TH1_k127_5309187_14 Universal stress protein family - - - 0.00000000000000006625 91.0
TH1_k127_5309187_15 Transcriptional regulator - - - 0.0000000006833 62.0
TH1_k127_5309187_2 Phosphoglycerate kinase K00927 - 2.7.2.3 1.902e-196 619.0
TH1_k127_5309187_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 500.0
TH1_k127_5309187_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 488.0
TH1_k127_5309187_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 430.0
TH1_k127_5309187_6 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 437.0
TH1_k127_5309187_7 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 399.0
TH1_k127_5309187_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 388.0
TH1_k127_5309187_9 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 354.0
TH1_k127_5360548_0 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 497.0
TH1_k127_5360548_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 399.0
TH1_k127_5360548_10 GAF domain - - - 0.00002042 46.0
TH1_k127_5360548_11 Membrane - - - 0.0003561 48.0
TH1_k127_5360548_2 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 317.0
TH1_k127_5360548_3 Acyl transferase domain K00645,K15327,K15329,K15469 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 304.0
TH1_k127_5360548_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002614 275.0
TH1_k127_5360548_5 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000002351 233.0
TH1_k127_5360548_6 YtkA-like - - - 0.0000000000000000000000000002861 125.0
TH1_k127_5360548_7 Protein of unknown function (DUF1622) - - - 0.0000000000000000000003238 101.0
TH1_k127_5370931_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009435 553.0
TH1_k127_5370931_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 394.0
TH1_k127_5370931_10 - - - - 0.0000003102 57.0
TH1_k127_5370931_11 - - - - 0.0008038 46.0
TH1_k127_5370931_2 Transcriptional regulator K11921,K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 380.0
TH1_k127_5370931_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002835 279.0
TH1_k127_5370931_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001916 260.0
TH1_k127_5370931_5 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000001307 243.0
TH1_k127_5370931_6 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000001238 214.0
TH1_k127_5370931_7 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000002499 216.0
TH1_k127_5370931_9 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000007002 122.0
TH1_k127_5375837_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 461.0
TH1_k127_5375837_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 395.0
TH1_k127_5375837_2 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000005429 93.0
TH1_k127_5388579_0 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 478.0
TH1_k127_5388579_1 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000004482 222.0
TH1_k127_5388579_2 Protein export membrane protein K03296,K18138 - - 0.0000000000000000000000000000000000002399 141.0
TH1_k127_5388579_3 Helix-turn-helix domain - - - 0.00000000000000000000000000002153 119.0
TH1_k127_5388579_4 Domain of unknown function (DUF4143) - - - 0.0000000103 60.0
TH1_k127_5457254_0 Belongs to the GPI family K01810 - 5.3.1.9 9.906e-268 833.0
TH1_k127_5457254_1 PD-(D/E)XK nuclease superfamily - - - 4.5e-225 733.0
TH1_k127_5457254_2 Belongs to the helicase family. UvrD subfamily - - - 5.037e-205 670.0
TH1_k127_5457254_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 327.0
TH1_k127_5457254_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001163 234.0
TH1_k127_5457254_5 aminopeptidase N - - - 0.000000000000000000000000000000000000000000000007295 183.0
TH1_k127_5457254_6 - - - - 0.000000000000000000000000000000000000000000001163 170.0
TH1_k127_5457254_7 NADPH-dependent FMN reductase K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000001466 53.0
TH1_k127_557786_0 transferase activity, transferring glycosyl groups K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 340.0
TH1_k127_557786_1 biosynthesis glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005329 243.0
TH1_k127_5589406_0 PFAM peptidase K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 423.0
TH1_k127_5589406_1 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 325.0
TH1_k127_5589406_10 Sporulation related domain - - - 0.0001006 53.0
TH1_k127_5589406_11 PFAM response regulator receiver K07662 - - 0.0002582 46.0
TH1_k127_5589406_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 324.0
TH1_k127_5589406_3 Mur ligase family, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 332.0
TH1_k127_5589406_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000795 233.0
TH1_k127_5589406_5 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000003799 219.0
TH1_k127_5589406_6 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000002648 212.0
TH1_k127_5589406_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000004138 208.0
TH1_k127_5589406_8 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000007641 188.0
TH1_k127_5589406_9 Stringent starvation protein B K09985 - - 0.000000000000000000000000000006721 123.0
TH1_k127_5606480_0 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002675 255.0
TH1_k127_5606480_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000007796 237.0
TH1_k127_5606480_2 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000006557 198.0
TH1_k127_5606480_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000001481 156.0
TH1_k127_5606480_4 protein conserved in bacteria - - - 0.000000000000000000005291 94.0
TH1_k127_5606480_6 PFAM Integrase core domain - - - 0.000006916 54.0
TH1_k127_5606480_7 SEC-C Motif Domain Protein - - - 0.0000527 53.0
TH1_k127_5606480_8 Tetratricopeptide repeat protein - - - 0.0001707 49.0
TH1_k127_5619_0 glycolate transport K14393 - - 2.232e-232 732.0
TH1_k127_5619_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000007328 246.0
TH1_k127_5619_2 - - - - 0.0000000000000000000000000000003324 127.0
TH1_k127_5619_3 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000004985 125.0
TH1_k127_5619_4 Replication initiation and membrane attachment - - - 0.0000000000000000000000001591 117.0
TH1_k127_5619_5 GAF domain K02584 - - 0.0000000000000000000000002923 123.0
TH1_k127_5619_6 Protein of unknown function, DUF485 - - - 0.000000000000000000000001906 105.0
TH1_k127_5619_7 DNA-templated transcription, initiation - - - 0.0000000000000002536 89.0
TH1_k127_5619_8 Helix-turn-helix domain - - - 0.0001691 51.0
TH1_k127_5645830_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.918e-264 826.0
TH1_k127_5645830_1 DEAD DEAH box helicase K06877 - - 7.247e-215 690.0
TH1_k127_5645830_10 - - - - 0.000001122 58.0
TH1_k127_5645830_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 363.0
TH1_k127_5645830_3 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 317.0
TH1_k127_5645830_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000003254 236.0
TH1_k127_5645830_5 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000004778 174.0
TH1_k127_5645830_6 Plasmid maintenance system killer K07334 - - 0.000000000000000000000000000000000003001 139.0
TH1_k127_5645830_7 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000000000000000007709 128.0
TH1_k127_5645830_8 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000004454 109.0
TH1_k127_5645830_9 protein-disulfide reductase activity - - - 0.00000000000000000000005482 104.0
TH1_k127_5682318_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1080.0
TH1_k127_5682318_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.895e-208 661.0
TH1_k127_5682318_10 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 321.0
TH1_k127_5682318_11 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 324.0
TH1_k127_5682318_12 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 315.0
TH1_k127_5682318_13 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 297.0
TH1_k127_5682318_14 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002888 297.0
TH1_k127_5682318_15 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001377 276.0
TH1_k127_5682318_16 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002116 276.0
TH1_k127_5682318_17 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000001458 239.0
TH1_k127_5682318_18 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000001844 215.0
TH1_k127_5682318_19 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000001245 202.0
TH1_k127_5682318_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 548.0
TH1_k127_5682318_20 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000001087 205.0
TH1_k127_5682318_21 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000007088 194.0
TH1_k127_5682318_22 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000005817 189.0
TH1_k127_5682318_23 Histidine kinase - - - 0.00000000000000000000000000000000000002321 148.0
TH1_k127_5682318_24 ECF sigma factor K03088 - - 0.00000000000000000000000000000000001702 142.0
TH1_k127_5682318_25 protein secretion K02460 - - 0.000000000000000000000000000002509 132.0
TH1_k127_5682318_26 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000003222 123.0
TH1_k127_5682318_27 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000002236 92.0
TH1_k127_5682318_28 Protein of unknown function (DUF3592) - - - 0.000000000000002143 87.0
TH1_k127_5682318_29 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000004369 81.0
TH1_k127_5682318_3 AAA ATPase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 460.0
TH1_k127_5682318_30 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000002863 62.0
TH1_k127_5682318_31 Fimbrial assembly protein (PilN) K02461 - - 0.0000000008316 71.0
TH1_k127_5682318_32 Belongs to the universal stress protein A family - - - 0.0000001621 60.0
TH1_k127_5682318_33 Integral membrane protein - - - 0.000004496 55.0
TH1_k127_5682318_34 Protein of unknown function (DUF3106) - - - 0.00007258 52.0
TH1_k127_5682318_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 425.0
TH1_k127_5682318_5 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 425.0
TH1_k127_5682318_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 416.0
TH1_k127_5682318_7 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 379.0
TH1_k127_5682318_8 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 374.0
TH1_k127_5682318_9 Bacterial type II and III secretion system protein K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 351.0
TH1_k127_5713547_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 342.0
TH1_k127_5713547_1 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000007564 156.0
TH1_k127_5742567_0 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 531.0
TH1_k127_5742567_1 GHKL domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 523.0
TH1_k127_5742567_10 Transposase IS200 like - - - 0.00000000008981 63.0
TH1_k127_5742567_2 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001902 270.0
TH1_k127_5742567_3 Large family of predicted nucleotide-binding domains - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000009806 177.0
TH1_k127_5742567_4 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000000592 171.0
TH1_k127_5742567_5 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000001466 171.0
TH1_k127_5742567_7 - - - - 0.00000000000000000000000001871 115.0
TH1_k127_5742567_8 PFAM Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.0000000000000000000000009674 106.0
TH1_k127_5742567_9 positive regulation of growth - - - 0.000000000000000000001488 95.0
TH1_k127_593132_0 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009229 286.0
TH1_k127_593132_1 PFAM response regulator receiver K02483,K18344 - - 0.000000000000000000000000000000000000000000000000000000000000000000004155 241.0
TH1_k127_593132_2 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001904 242.0
TH1_k127_593132_3 RNA-binding protein containing a PIN domain K06962 - - 0.00000000000000000000003876 104.0
TH1_k127_6002210_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 537.0
TH1_k127_6002210_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 535.0
TH1_k127_6002210_2 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 290.0
TH1_k127_6002210_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007851 304.0
TH1_k127_6002210_4 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000000008368 181.0
TH1_k127_6002210_5 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000001381 150.0
TH1_k127_6002210_6 chemotaxis protein K03408 - - 0.00000000000000000004529 98.0
TH1_k127_6002210_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000001966 58.0
TH1_k127_6002210_8 PBP superfamily domain K02040 - - 0.000001045 55.0
TH1_k127_6002210_9 Periplasmic or secreted lipoprotein - - - 0.00001821 46.0
TH1_k127_6070308_0 O-methyltransferase activity - - - 6.625e-212 678.0
TH1_k127_6070308_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 517.0
TH1_k127_6070308_10 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000000006989 121.0
TH1_k127_6070308_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 413.0
TH1_k127_6070308_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 330.0
TH1_k127_6070308_4 S1 domain K00243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 308.0
TH1_k127_6070308_5 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 295.0
TH1_k127_6070308_6 Oligoendopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006909 284.0
TH1_k127_6070308_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006147 268.0
TH1_k127_6070308_8 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003863 243.0
TH1_k127_6070308_9 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004099 233.0
TH1_k127_6096886_0 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 497.0
TH1_k127_6096886_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 371.0
TH1_k127_6096886_2 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008986 258.0
TH1_k127_6096886_3 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000004908 237.0
TH1_k127_6096886_4 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000005189 231.0
TH1_k127_6096886_5 Peptidase S24-like K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000005621 218.0
TH1_k127_6096886_6 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000003264 216.0
TH1_k127_6096886_7 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000003206 198.0
TH1_k127_6096886_8 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000002038 140.0
TH1_k127_6096886_9 - - - - 0.000000000000000000000004235 108.0
TH1_k127_6114525_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007207 263.0
TH1_k127_6114525_3 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000007157 65.0
TH1_k127_6114525_4 Terminase RNaseH-like domain - - - 0.000003906 59.0
TH1_k127_6154023_0 NADH-quinone oxidoreductase subunit F K18005 - 1.12.1.2 1.718e-248 781.0
TH1_k127_6154023_1 NADH ubiquinone oxidoreductase K18006,K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 376.0
TH1_k127_6154023_2 Coenzyme F420-reducing hydrogenase, gamma subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 305.0
TH1_k127_617845_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 599.0
TH1_k127_617845_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001753 246.0
TH1_k127_617845_2 UTRA K03710 - - 0.00000000000000000000000000000000008895 142.0
TH1_k127_617845_3 AMP binding - - - 0.0000000000000000000000000000000001259 137.0
TH1_k127_6189402_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000002269 182.0
TH1_k127_6189402_1 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000003576 158.0
TH1_k127_6189402_2 Protein of unknown function (DUF507) - - - 0.00000000000000000000000000006097 118.0
TH1_k127_6189402_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000005383 114.0
TH1_k127_6189402_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000434 109.0
TH1_k127_6189402_5 Protein of unknown function (DUF507) - - - 0.000000000000000000001276 97.0
TH1_k127_6189402_6 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000001514 63.0
TH1_k127_6195737_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1209.0
TH1_k127_6195737_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.694e-194 628.0
TH1_k127_6195737_10 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 331.0
TH1_k127_6195737_11 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 297.0
TH1_k127_6195737_12 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006326 282.0
TH1_k127_6195737_13 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02236,K02278,K02506,K02654,K10966 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 266.0
TH1_k127_6195737_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000003716 263.0
TH1_k127_6195737_15 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000001157 258.0
TH1_k127_6195737_16 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001143 256.0
TH1_k127_6195737_17 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001312 231.0
TH1_k127_6195737_18 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000318 218.0
TH1_k127_6195737_19 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000001309 220.0
TH1_k127_6195737_2 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 612.0
TH1_k127_6195737_20 - - - - 0.00000000000000000000000000000000000000000000000001019 186.0
TH1_k127_6195737_21 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000008308 188.0
TH1_k127_6195737_22 DoxX K15977 - - 0.000000000000000000000000000000000000000000000001683 176.0
TH1_k127_6195737_23 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.00000000000000000000000000000000000000000000004592 179.0
TH1_k127_6195737_24 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000403 171.0
TH1_k127_6195737_25 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000002602 169.0
TH1_k127_6195737_26 - - - - 0.00000000000000000000000000000000002173 141.0
TH1_k127_6195737_27 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000004545 142.0
TH1_k127_6195737_29 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000004773 116.0
TH1_k127_6195737_3 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 578.0
TH1_k127_6195737_30 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000004565 108.0
TH1_k127_6195737_31 Polymer-forming cytoskeletal - - - 0.00000000000000000006045 94.0
TH1_k127_6195737_32 Protein of unknown function (DUF1189) - - - 0.00000000000000000009479 99.0
TH1_k127_6195737_33 Protein of unknown function DUF262 - - - 0.000000000000000003405 95.0
TH1_k127_6195737_34 Protein of unknown function (DUF2905) - - - 0.00000000000000001865 85.0
TH1_k127_6195737_35 - - - - 0.00000000000000008583 81.0
TH1_k127_6195737_36 - - - - 0.000000000003413 70.0
TH1_k127_6195737_37 Ribosomal RNA adenine dimethylase - - - 0.000000000005034 73.0
TH1_k127_6195737_38 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000002291 59.0
TH1_k127_6195737_39 - - - - 0.0000007305 54.0
TH1_k127_6195737_4 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 497.0
TH1_k127_6195737_40 COG2200 FOG EAL domain K20963 - 3.1.4.52 0.0000007681 58.0
TH1_k127_6195737_42 - - - - 0.0002103 45.0
TH1_k127_6195737_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 480.0
TH1_k127_6195737_6 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 452.0
TH1_k127_6195737_7 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 429.0
TH1_k127_6195737_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 336.0
TH1_k127_6195737_9 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 334.0
TH1_k127_6196438_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 525.0
TH1_k127_6196438_1 Glycosyl hydrolase family 63 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001809 233.0
TH1_k127_6196438_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000000578 165.0
TH1_k127_6196438_3 AI-2E family transporter - - - 0.000000000000000000000001891 103.0
TH1_k127_6196438_4 PFAM SpoVT AbrB domain protein K07172 - - 0.000000000000000000007046 94.0
TH1_k127_6196438_5 - - - - 0.00009331 47.0
TH1_k127_6212129_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 425.0
TH1_k127_6212129_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 340.0
TH1_k127_6212129_2 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000004677 166.0
TH1_k127_6212129_3 Cell division protein FtsQ K03589 - - 0.000000003733 67.0
TH1_k127_6250674_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 308.0
TH1_k127_6250674_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001621 282.0
TH1_k127_6250674_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002253 275.0
TH1_k127_62738_0 4Fe-4S dicluster domain - - - 1.789e-303 936.0
TH1_k127_62738_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.207e-229 721.0
TH1_k127_62738_10 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 486.0
TH1_k127_62738_11 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 424.0
TH1_k127_62738_12 PFAM Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 413.0
TH1_k127_62738_13 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 348.0
TH1_k127_62738_14 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 345.0
TH1_k127_62738_15 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 334.0
TH1_k127_62738_16 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 329.0
TH1_k127_62738_17 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 337.0
TH1_k127_62738_18 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003522 271.0
TH1_k127_62738_19 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000321 265.0
TH1_k127_62738_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 9.373e-225 709.0
TH1_k127_62738_20 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002311 255.0
TH1_k127_62738_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001063 234.0
TH1_k127_62738_22 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000008564 231.0
TH1_k127_62738_23 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000001978 223.0
TH1_k127_62738_24 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000006467 205.0
TH1_k127_62738_25 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000001892 201.0
TH1_k127_62738_26 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000008049 203.0
TH1_k127_62738_27 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.0000000000000000000000000000000000000000000000000005422 188.0
TH1_k127_62738_28 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000008114 189.0
TH1_k127_62738_29 - - - - 0.0000000000000000000000000000000000000000000000005686 177.0
TH1_k127_62738_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 9.291e-209 669.0
TH1_k127_62738_30 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000002649 177.0
TH1_k127_62738_31 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.0000000000000000000000000000000000000000000008953 172.0
TH1_k127_62738_32 MgtC family K07507 - - 0.00000000000000000000000000000000000001233 152.0
TH1_k127_62738_33 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000003334 150.0
TH1_k127_62738_34 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000007993 136.0
TH1_k127_62738_35 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.00000000000000000000000000007103 121.0
TH1_k127_62738_36 - - - - 0.000000000000000000000000007783 109.0
TH1_k127_62738_37 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000001697 117.0
TH1_k127_62738_38 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.00000000000000000000001178 109.0
TH1_k127_62738_39 - - - - 0.00000000000000000000008092 101.0
TH1_k127_62738_4 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 564.0
TH1_k127_62738_40 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000009085 84.0
TH1_k127_62738_41 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.00000000000000001329 87.0
TH1_k127_62738_42 Tetratricopeptide repeat-like domain - - - 0.000000000000001636 85.0
TH1_k127_62738_43 lyase activity - - - 0.00000000000001803 78.0
TH1_k127_62738_44 nuclease activity - - - 0.00000000005572 69.0
TH1_k127_62738_45 DsrE/DsrF-like family K07235 - - 0.000000002534 63.0
TH1_k127_62738_46 sulfur carrier activity - - - 0.00000000599 60.0
TH1_k127_62738_47 energy transducer activity K03832 - - 0.00000001664 65.0
TH1_k127_62738_48 Thioredoxin K03672 - 1.8.1.8 0.00003306 53.0
TH1_k127_62738_49 - - - - 0.00009713 50.0
TH1_k127_62738_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 572.0
TH1_k127_62738_50 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.0003627 47.0
TH1_k127_62738_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 545.0
TH1_k127_62738_7 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 540.0
TH1_k127_62738_8 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 524.0
TH1_k127_62738_9 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 522.0
TH1_k127_6309252_0 Tetratricopeptide repeat - - - 1.947e-196 635.0
TH1_k127_6309252_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 469.0
TH1_k127_6309252_2 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 329.0
TH1_k127_6309252_3 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000567 221.0
TH1_k127_6309252_4 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000005436 191.0
TH1_k127_6309252_5 Collagen triple helix - - - 0.00000000000000000000003709 111.0
TH1_k127_6321911_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000009402 145.0
TH1_k127_6321911_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000007959 95.0
TH1_k127_6327619_0 Sigma-54 interaction domain K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 419.0
TH1_k127_6327619_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 379.0
TH1_k127_6327619_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000004451 231.0
TH1_k127_6327619_11 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000004257 219.0
TH1_k127_6327619_12 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000005184 208.0
TH1_k127_6327619_13 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000001786 172.0
TH1_k127_6327619_14 cobalamin synthesis protein, P47K - - - 0.000000000000000000000000000000000000000000003021 176.0
TH1_k127_6327619_15 Transcriptional regulator K02019,K05772 - - 0.00000000000000000000000000000000000001708 149.0
TH1_k127_6327619_16 nitric oxide reductase activity - - - 0.0000000000000000000000000000000000001172 143.0
TH1_k127_6327619_17 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000007666 113.0
TH1_k127_6327619_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 295.0
TH1_k127_6327619_22 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 0.00000006091 59.0
TH1_k127_6327619_23 Belongs to the peptidase M48B family K03799 - - 0.0008306 51.0
TH1_k127_6327619_3 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 305.0
TH1_k127_6327619_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 304.0
TH1_k127_6327619_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004639 274.0
TH1_k127_6327619_6 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000001596 269.0
TH1_k127_6327619_7 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 257.0
TH1_k127_6327619_8 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007473 240.0
TH1_k127_6327619_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001175 255.0
TH1_k127_6328116_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 372.0
TH1_k127_6328116_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 349.0
TH1_k127_6328116_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001492 273.0
TH1_k127_6328116_3 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000001631 229.0
TH1_k127_6328116_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000007517 177.0
TH1_k127_6328116_5 - - - - 0.00000000000000000000000000000000000002878 153.0
TH1_k127_6328116_6 radical SAM domain protein - - - 0.0000000000000000000000000000002942 136.0
TH1_k127_6328116_7 TIGRFAM Protein of - - - 0.0000000000000000000000003126 108.0
TH1_k127_6328116_8 S4 domain K14761 - - 0.000000000000000000009283 93.0
TH1_k127_6328116_9 PilZ domain - - - 0.0003447 52.0
TH1_k127_633661_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 492.0
TH1_k127_633661_1 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000002592 226.0
TH1_k127_633661_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000003095 84.0
TH1_k127_6336862_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 502.0
TH1_k127_6336862_1 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 398.0
TH1_k127_6336862_2 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 302.0
TH1_k127_6336862_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000302 243.0
TH1_k127_6336862_4 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.000000000000000000000000000000000000000000000000000000000000001511 230.0
TH1_k127_6336862_5 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000001466 141.0
TH1_k127_6336862_6 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000001217 63.0
TH1_k127_6344993_0 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002764 239.0
TH1_k127_6344993_1 - - - - 0.0000000000000000000000000000005166 126.0
TH1_k127_6344993_2 Methyltransferase - - - 0.0000000000006943 78.0
TH1_k127_6376075_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002871 236.0
TH1_k127_6376075_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000186 228.0
TH1_k127_6376075_2 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000001935 172.0
TH1_k127_6376075_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000001548 151.0
TH1_k127_64288_0 PFAM ribonuclease II K01147 - 3.1.13.1 3.492e-209 660.0
TH1_k127_64288_1 Flavodoxin-like fold K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000000000000000000000000004707 135.0
TH1_k127_64288_2 cell redox homeostasis - - - 0.000000000000000000000000002422 111.0
TH1_k127_6454042_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 322.0
TH1_k127_6454042_1 TIGRFAM PAS domain S-box - - - 0.0000000000000000000000000000000000000000000000000000000000001616 232.0
TH1_k127_6454042_2 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000006248 151.0
TH1_k127_6454042_3 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000002458 123.0
TH1_k127_6454042_4 RNA-binding protein - - - 0.00000000000000000000001237 104.0
TH1_k127_6454042_5 PFAM Lytic transglycosylase catalytic - - - 0.000000004097 66.0
TH1_k127_6454042_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0004828 44.0
TH1_k127_6467879_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 365.0
TH1_k127_6467879_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000003003 178.0
TH1_k127_6467879_3 MGS-like domain - - - 0.000000000000000000000000000000000000000000000003161 181.0
TH1_k127_6467879_4 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000001445 164.0
TH1_k127_6467879_5 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000001266 100.0
TH1_k127_6483701_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 1.191e-224 712.0
TH1_k127_6483701_1 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 1.612e-214 686.0
TH1_k127_6483701_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 582.0
TH1_k127_6483701_3 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 358.0
TH1_k127_6483701_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000001792 192.0
TH1_k127_6483701_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.00000000000000000000000000000000000000000000000193 179.0
TH1_k127_6483701_6 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000001304 157.0
TH1_k127_6483701_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000001161 53.0
TH1_k127_6483701_8 Tetratricopeptide repeat - - - 0.0001422 53.0
TH1_k127_6531436_0 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 604.0
TH1_k127_6531436_1 GTP-binding GTPase Middle Region K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 598.0
TH1_k127_6531436_10 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 289.0
TH1_k127_6531436_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005933 293.0
TH1_k127_6531436_12 PFAM ABC transporter related K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002953 277.0
TH1_k127_6531436_13 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003037 255.0
TH1_k127_6531436_14 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.000000000000000000000000000000000000000000000000000000000207 207.0
TH1_k127_6531436_15 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000297 205.0
TH1_k127_6531436_16 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000002169 198.0
TH1_k127_6531436_17 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000009342 184.0
TH1_k127_6531436_18 Belongs to the Fur family K02076,K03711 GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000038 176.0
TH1_k127_6531436_19 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000005639 173.0
TH1_k127_6531436_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 581.0
TH1_k127_6531436_20 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000025 168.0
TH1_k127_6531436_21 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.00000000000000000000000000000000000000000008055 166.0
TH1_k127_6531436_22 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.0000000000000000000000000000000000000000005136 160.0
TH1_k127_6531436_23 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000004194 134.0
TH1_k127_6531436_24 Protein of unknown function DUF134 - - - 0.000000000000000000000000004667 113.0
TH1_k127_6531436_25 CRISPR-associated helicase, Cas3 K07012 - - 0.0000000000000000000000002177 108.0
TH1_k127_6531436_26 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000001896 98.0
TH1_k127_6531436_27 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000009366 96.0
TH1_k127_6531436_28 DEAD-like helicases superfamily K07012 - - 0.00000000001533 72.0
TH1_k127_6531436_29 PFAM DsrE DsrF-like family - - - 0.0000000001461 66.0
TH1_k127_6531436_3 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 465.0
TH1_k127_6531436_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 457.0
TH1_k127_6531436_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 424.0
TH1_k127_6531436_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 423.0
TH1_k127_6531436_7 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 400.0
TH1_k127_6531436_8 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 347.0
TH1_k127_6531436_9 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 324.0
TH1_k127_6595231_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.588e-239 751.0
TH1_k127_6595231_1 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 434.0
TH1_k127_6595231_10 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005662 265.0
TH1_k127_6595231_11 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003002 256.0
TH1_k127_6595231_12 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004988 242.0
TH1_k127_6595231_13 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000004494 228.0
TH1_k127_6595231_14 photoreceptor activity K02007,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001093 237.0
TH1_k127_6595231_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000002123 215.0
TH1_k127_6595231_16 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000000000009736 205.0
TH1_k127_6595231_17 Oxidoreductase NAD-binding domain K02823 - - 0.000000000000000000000000000000000000000000000000004357 190.0
TH1_k127_6595231_18 response regulator K02485 - - 0.0000000000000000000000000000000000000000000000005226 178.0
TH1_k127_6595231_19 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000003035 112.0
TH1_k127_6595231_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 413.0
TH1_k127_6595231_20 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K12276 - - 0.0000000000000000006792 97.0
TH1_k127_6595231_21 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.000000000000000004758 83.0
TH1_k127_6595231_22 Uncharacterized integral membrane protein (DUF2301) - - - 0.0000000002107 69.0
TH1_k127_6595231_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 422.0
TH1_k127_6595231_4 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 392.0
TH1_k127_6595231_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 350.0
TH1_k127_6595231_6 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 323.0
TH1_k127_6595231_7 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 326.0
TH1_k127_6595231_8 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 297.0
TH1_k127_6595231_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 299.0
TH1_k127_6615055_0 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 381.0
TH1_k127_6615055_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002588 266.0
TH1_k127_6615055_2 DNA-binding transcription factor activity K03710 - - 0.00000000000000000000000000000000000000000000000000000000000001979 222.0
TH1_k127_6615055_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000002661 183.0
TH1_k127_6615055_4 IMP dehydrogenase activity - - - 0.000000000000000000000000000009988 124.0
TH1_k127_6615055_5 response regulator, receiver - - - 0.000000000000000000000001509 107.0
TH1_k127_6615055_6 Histidine kinase - - - 0.00000000003566 72.0
TH1_k127_6615661_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 544.0
TH1_k127_6615661_1 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000001474 215.0
TH1_k127_6615661_2 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000009516 214.0
TH1_k127_6615661_3 virion core protein, lumpy skin disease virus - - - 0.0000000000000000000000000000000000000000000000000000000001366 210.0
TH1_k127_6615661_4 Permease MlaE K02066 - - 0.000000000000000000000000009823 110.0
TH1_k127_6615661_5 Protein of unknown function (DUF1232) - - - 0.000000000000000000000001663 105.0
TH1_k127_6615661_6 cheY-homologous receiver domain - - - 0.000000000000000000000002817 110.0
TH1_k127_6615661_7 phosphorelay signal transduction system - - - 0.0000000000000000000009856 98.0
TH1_k127_6628435_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.813e-315 990.0
TH1_k127_6628435_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.063e-268 835.0
TH1_k127_6628435_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000002626 142.0
TH1_k127_6628435_11 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000001013 74.0
TH1_k127_6628435_2 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 580.0
TH1_k127_6628435_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 567.0
TH1_k127_6628435_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 464.0
TH1_k127_6628435_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 313.0
TH1_k127_6628435_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 290.0
TH1_k127_6628435_7 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000004317 237.0
TH1_k127_6628435_8 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000009512 198.0
TH1_k127_6628435_9 protein conserved in bacteria K09922 - - 0.0000000000000000000000000000000000000002327 150.0
TH1_k127_6640064_0 Fic/DOC family K07341 - - 0.0000000000000000000000000003426 118.0
TH1_k127_6640064_2 Putative diguanylate phosphodiesterase - - - 0.000000000000000000001118 107.0
TH1_k127_6640064_4 Tetratricopeptide repeat - - - 0.0004185 44.0
TH1_k127_6727321_0 ABC transporter K15738 - - 1.273e-230 730.0
TH1_k127_6727321_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 606.0
TH1_k127_6727321_2 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 485.0
TH1_k127_6727321_3 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 338.0
TH1_k127_6727321_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000000000000000000000000000000000000000000000000000007432 205.0
TH1_k127_6727321_5 domain protein K20276 - - 0.000000000000000001126 97.0
TH1_k127_6727321_6 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.0000000000068 76.0
TH1_k127_6727321_7 - - - - 0.000000000134 66.0
TH1_k127_6756041_0 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 372.0
TH1_k127_6756041_1 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 353.0
TH1_k127_6756041_2 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 302.0
TH1_k127_6756041_3 - - - - 0.0000000000000000000000000000000000000000000000000000000001749 210.0
TH1_k127_6756041_4 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000009069 199.0
TH1_k127_6756041_5 AMP-binding enzyme C-terminal domain K16029 - - 0.00000000000000000000000000000000000000000000000003867 197.0
TH1_k127_6756041_6 Membrane protein involved in D-alanine export - - - 0.0000000000000000000000000000000000000001533 167.0
TH1_k127_6756041_7 Domain of unknown function (DUF386) - - - 0.0000000000000000000000000000005432 127.0
TH1_k127_6756041_8 Phosphopantetheine attachment site - - - 0.000001833 53.0
TH1_k127_6773928_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2072.0
TH1_k127_6773928_1 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1628.0
TH1_k127_6773928_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 329.0
TH1_k127_6773928_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001157 259.0
TH1_k127_6773928_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000002394 219.0
TH1_k127_6773928_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000007544 189.0
TH1_k127_6773928_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000003131 143.0
TH1_k127_6773928_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000008823 74.0
TH1_k127_6773928_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000001089 74.0
TH1_k127_6773928_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000002438 74.0
TH1_k127_6803835_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 575.0
TH1_k127_6803835_1 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 457.0
TH1_k127_6803835_2 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 284.0
TH1_k127_6803835_3 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000000000001089 167.0
TH1_k127_6810005_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 564.0
TH1_k127_6810005_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 355.0
TH1_k127_6810005_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000285 200.0
TH1_k127_6810005_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000002353 191.0
TH1_k127_6810005_4 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000008162 134.0
TH1_k127_6842305_0 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 581.0
TH1_k127_6842305_1 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 468.0
TH1_k127_6842305_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 286.0
TH1_k127_6863948_0 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 364.0
TH1_k127_6863948_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000447 297.0
TH1_k127_6863948_2 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K00773,K07319,K11782,K15461 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005869 284.0
TH1_k127_6863948_3 PFAM MscS Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000001312 164.0
TH1_k127_6980529_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.456e-207 653.0
TH1_k127_6980529_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 384.0
TH1_k127_6980529_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000007152 214.0
TH1_k127_6980529_11 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000002267 216.0
TH1_k127_6980529_12 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006836 200.0
TH1_k127_6980529_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000434 198.0
TH1_k127_6980529_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000009398 197.0
TH1_k127_6980529_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001416 183.0
TH1_k127_6980529_16 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000003482 179.0
TH1_k127_6980529_17 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000001015 166.0
TH1_k127_6980529_18 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001641 157.0
TH1_k127_6980529_19 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000007011 151.0
TH1_k127_6980529_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 347.0
TH1_k127_6980529_20 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000004098 147.0
TH1_k127_6980529_21 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000003871 134.0
TH1_k127_6980529_22 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000006061 133.0
TH1_k127_6980529_23 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000001655 130.0
TH1_k127_6980529_24 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006812 107.0
TH1_k127_6980529_25 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000007692 109.0
TH1_k127_6980529_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000004445 106.0
TH1_k127_6980529_27 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000003859 79.0
TH1_k127_6980529_28 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000008823 74.0
TH1_k127_6980529_29 Ribosomal protein L36 K02919 - - 0.00000000000001418 73.0
TH1_k127_6980529_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 337.0
TH1_k127_6980529_30 Ribosomal protein L30 K02907 - - 0.0000000001375 63.0
TH1_k127_6980529_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 315.0
TH1_k127_6980529_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001044 277.0
TH1_k127_6980529_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000632 278.0
TH1_k127_6980529_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001142 273.0
TH1_k127_6980529_8 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000002526 231.0
TH1_k127_6980529_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000006061 233.0
TH1_k127_7046402_0 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000006207 233.0
TH1_k127_7046402_1 Domain of Unknown Function (DUF350) K08989 - - 0.000000000000000000000000000000000288 137.0
TH1_k127_7046402_2 thiolester hydrolase activity - - - 0.0000000000000000000000007858 108.0
TH1_k127_7046402_3 Glutathionylspermidine synthase preATP-grasp - - - 0.00000000000000000000003748 101.0
TH1_k127_7214079_0 ABC-type polar amino acid transport system ATPase component K09972 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 298.0
TH1_k127_7214079_1 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002192 259.0
TH1_k127_7358821_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 581.0
TH1_k127_7358821_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 445.0
TH1_k127_7358821_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000000000000000000000000000004008 213.0
TH1_k127_7358821_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000006732 144.0
TH1_k127_7373424_0 Domain of unknown function (DUF4139) - - - 1.234e-204 647.0
TH1_k127_7373424_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000004216 199.0
TH1_k127_7373424_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000368 191.0
TH1_k127_7373424_3 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000003595 173.0
TH1_k127_7373424_4 Putative zinc-finger - - - 0.0000000000000000000003989 108.0
TH1_k127_7373424_5 Cytochrome c K08738 - - 0.0000000000000000001185 93.0
TH1_k127_7373424_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000001256 55.0
TH1_k127_7373424_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000002152 61.0
TH1_k127_7396573_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 447.0
TH1_k127_7396573_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 406.0
TH1_k127_7396573_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 353.0
TH1_k127_7396573_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 319.0
TH1_k127_7396573_4 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000004264 200.0
TH1_k127_7396573_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000001846 177.0
TH1_k127_7396573_6 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000000000004283 155.0
TH1_k127_7396573_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657 - 0.00000000158 66.0
TH1_k127_7396573_8 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000001733 59.0
TH1_k127_7474816_0 Phage tail sheath C-terminal domain K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 515.0
TH1_k127_7474816_1 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.000000000000000000000000000000000001214 148.0
TH1_k127_7482941_0 Amino acid adenylation domain protein - - - 2.23e-223 712.0
TH1_k127_7482941_1 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 510.0
TH1_k127_7482941_10 PFAM Fibronectin type III domain - - - 0.0005081 44.0
TH1_k127_7482941_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain K06445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 471.0
TH1_k127_7482941_3 phosphopantetheine binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 431.0
TH1_k127_7482941_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 380.0
TH1_k127_7482941_5 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 316.0
TH1_k127_7482941_6 Amino acid ABC transporter substrate-binding protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000271 269.0
TH1_k127_7482941_7 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000002086 232.0
TH1_k127_7482941_8 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000002242 228.0
TH1_k127_7482941_9 Phosphopantetheine attachment site - - - 0.000000000000000000003443 95.0
TH1_k127_7507906_0 Bacterial protein of unknown function (DUF853) K06915 - - 4.017e-216 679.0
TH1_k127_7507906_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 594.0
TH1_k127_7507906_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000005931 61.0
TH1_k127_7507906_11 Transcriptional regulator - - - 0.0000595 53.0
TH1_k127_7507906_2 PFAM UvrD REP helicase K03656,K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 601.0
TH1_k127_7507906_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000177 265.0
TH1_k127_7507906_4 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000134 210.0
TH1_k127_7507906_5 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000000000004505 211.0
TH1_k127_7507906_6 Helicase K03579 - 3.6.4.13 0.000000000000000000000000000000000000000000002764 164.0
TH1_k127_7507906_7 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000663 156.0
TH1_k127_7507906_8 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000002538 115.0
TH1_k127_7507906_9 - - - - 0.0000000000000000000000002799 109.0
TH1_k127_7514805_0 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 526.0
TH1_k127_7514805_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 451.0
TH1_k127_7514805_10 Radical SAM domain protein - - - 0.000000000000000000000000000000000002402 145.0
TH1_k127_7514805_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000002604 139.0
TH1_k127_7514805_12 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000175 138.0
TH1_k127_7514805_13 Domain of unknown function (DUF4410) - - - 0.0000000000000000000002237 105.0
TH1_k127_7514805_14 Cysteine-rich small domain - - - 0.000000000000000001631 87.0
TH1_k127_7514805_15 response regulator, receiver K03413 - - 0.00000000000000000207 90.0
TH1_k127_7514805_16 FecR protein - - - 0.00000000001493 74.0
TH1_k127_7514805_17 Belongs to the peptidase S26 family - - - 0.0000000001268 70.0
TH1_k127_7514805_18 Multidrug transporter - - - 0.00000004563 59.0
TH1_k127_7514805_19 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000003104 63.0
TH1_k127_7514805_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 318.0
TH1_k127_7514805_20 PFAM TPR repeat-containing protein - - - 0.0000003284 63.0
TH1_k127_7514805_3 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004884 281.0
TH1_k127_7514805_4 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000000000000005407 207.0
TH1_k127_7514805_5 - - - - 0.00000000000000000000000000000000000000000000000894 174.0
TH1_k127_7514805_6 Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000004032 176.0
TH1_k127_7514805_7 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000003517 174.0
TH1_k127_7514805_8 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000004237 153.0
TH1_k127_7514805_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000281 149.0
TH1_k127_7548198_0 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 451.0
TH1_k127_7548198_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000002099 241.0
TH1_k127_7548198_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000001377 150.0
TH1_k127_7548198_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.00000000000000000000000000004874 116.0
TH1_k127_7661997_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 561.0
TH1_k127_7661997_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000006652 202.0
TH1_k127_7661997_2 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000004905 159.0
TH1_k127_7661997_3 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000002225 151.0
TH1_k127_7661997_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000007006 115.0
TH1_k127_7661997_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000002679 81.0
TH1_k127_7686443_0 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 328.0
TH1_k127_7686443_1 Transcriptional regulator - - - 0.00000000000000000000000000000764 121.0
TH1_k127_7686443_2 addiction module killer protein - - - 0.00000000000000000000000000007826 117.0
TH1_k127_7686443_3 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.00000000000000000007853 93.0
TH1_k127_7686443_4 domain protein - - - 0.0005006 48.0
TH1_k127_7686716_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1103.0
TH1_k127_7686716_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 566.0
TH1_k127_7686716_10 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006159 302.0
TH1_k127_7686716_11 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000004773 268.0
TH1_k127_7686716_12 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000001045 269.0
TH1_k127_7686716_13 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004784 247.0
TH1_k127_7686716_14 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000000000000000000001549 209.0
TH1_k127_7686716_15 Domain of unknown function (DUF3842) - - - 0.00000000000000000000000000000000000000000000000000005253 189.0
TH1_k127_7686716_16 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000000002644 179.0
TH1_k127_7686716_17 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000006654 160.0
TH1_k127_7686716_18 Tetratricopeptide repeat - - - 0.000000000000000000000000001041 119.0
TH1_k127_7686716_19 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000001437 83.0
TH1_k127_7686716_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 576.0
TH1_k127_7686716_3 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 397.0
TH1_k127_7686716_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 386.0
TH1_k127_7686716_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 386.0
TH1_k127_7686716_6 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 337.0
TH1_k127_7686716_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 339.0
TH1_k127_7686716_8 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 335.0
TH1_k127_7686716_9 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 340.0
TH1_k127_7698470_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 1.677e-232 728.0
TH1_k127_7698470_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 535.0
TH1_k127_7698470_10 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000004434 155.0
TH1_k127_7698470_11 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000533 146.0
TH1_k127_7698470_12 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000003023 128.0
TH1_k127_7698470_13 HupF/HypC family K04653 - - 0.0000000000000000003501 89.0
TH1_k127_7698470_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 487.0
TH1_k127_7698470_3 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 418.0
TH1_k127_7698470_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 396.0
TH1_k127_7698470_5 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 388.0
TH1_k127_7698470_6 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 300.0
TH1_k127_7698470_7 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002996 270.0
TH1_k127_7698470_8 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000000007928 183.0
TH1_k127_7698470_9 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000001018 174.0
TH1_k127_7710814_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 598.0
TH1_k127_7710814_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 593.0
TH1_k127_7710814_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 543.0
TH1_k127_7710814_3 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 330.0
TH1_k127_7710814_4 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000366 264.0
TH1_k127_7710814_5 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003616 248.0
TH1_k127_7710814_6 PFAM Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000003988 240.0
TH1_k127_7710814_7 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000002505 163.0
TH1_k127_7710814_8 Diguanylate cyclase, GGDEF domain - - - 0.000000000000006716 83.0
TH1_k127_771673_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.778e-251 794.0
TH1_k127_771673_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.907e-231 729.0
TH1_k127_771673_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 528.0
TH1_k127_771673_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 436.0
TH1_k127_771673_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006771 320.0
TH1_k127_771673_5 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 312.0
TH1_k127_771673_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000009613 151.0
TH1_k127_771673_7 YbbR-like protein - - - 0.000000000000000000000000000000000000009919 153.0
TH1_k127_771673_8 Glu-tRNAGln amidotransferase C subunit K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000002812 116.0
TH1_k127_771673_9 - - - - 0.000000000983 62.0
TH1_k127_774567_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009143 542.0
TH1_k127_774567_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000001974 190.0
TH1_k127_774567_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000001885 66.0
TH1_k127_7751349_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.036e-273 856.0
TH1_k127_7751349_1 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 2.929e-201 645.0
TH1_k127_7751349_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000001523 261.0
TH1_k127_7751349_11 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000003653 242.0
TH1_k127_7751349_12 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step K05985,K07476 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 0.000000000000000000000000000000000000000009122 158.0
TH1_k127_7751349_13 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000007008 110.0
TH1_k127_7751349_2 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 535.0
TH1_k127_7751349_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 526.0
TH1_k127_7751349_4 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 523.0
TH1_k127_7751349_5 Extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 446.0
TH1_k127_7751349_6 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 417.0
TH1_k127_7751349_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 400.0
TH1_k127_7751349_8 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 308.0
TH1_k127_7751349_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005797 282.0
TH1_k127_77721_0 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 502.0
TH1_k127_77721_1 Porphobilinogen deaminase, dipyromethane cofactor binding domain K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 381.0
TH1_k127_77721_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000002057 228.0
TH1_k127_77721_3 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000007486 204.0
TH1_k127_77721_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000001374 175.0
TH1_k127_77721_5 - - - - 0.00000000001482 66.0
TH1_k127_7784341_0 Phospholipid methyltransferase - - - 0.00000000000000000004099 98.0
TH1_k127_7784341_1 PFAM Integrase catalytic - - - 0.0000000000000322 78.0
TH1_k127_7784341_2 sequence-specific DNA binding - - - 0.000000002629 63.0
TH1_k127_7795787_0 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 292.0
TH1_k127_7795787_1 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002286 280.0
TH1_k127_7795787_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000183 278.0
TH1_k127_7795787_3 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000003869 112.0
TH1_k127_7795787_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000008871 64.0
TH1_k127_7805596_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.582e-311 970.0
TH1_k127_7805596_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.855e-262 829.0
TH1_k127_7805596_10 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 375.0
TH1_k127_7805596_11 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 361.0
TH1_k127_7805596_12 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 337.0
TH1_k127_7805596_13 membrane K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 334.0
TH1_k127_7805596_14 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 320.0
TH1_k127_7805596_15 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 297.0
TH1_k127_7805596_16 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002483 286.0
TH1_k127_7805596_17 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000132 276.0
TH1_k127_7805596_18 ATP cone domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007988 259.0
TH1_k127_7805596_19 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 255.0
TH1_k127_7805596_2 SMART Elongator protein 3 MiaB NifB - - - 5.529e-223 701.0
TH1_k127_7805596_20 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000003694 230.0
TH1_k127_7805596_21 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000002063 226.0
TH1_k127_7805596_22 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000000000000000000414 207.0
TH1_k127_7805596_23 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000008509 212.0
TH1_k127_7805596_24 Belongs to the DsbB family K03611 - - 0.000000000000000000000000000000000000000000001846 170.0
TH1_k127_7805596_25 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000002019 157.0
TH1_k127_7805596_26 NTPase - - - 0.000000000000000000000000000000000000004082 151.0
TH1_k127_7805596_27 translation release factor activity - - - 0.00000000000000000000000000000000000001571 149.0
TH1_k127_7805596_28 DivIVA protein K04074 - - 0.00000000000000000000002306 105.0
TH1_k127_7805596_29 - - - - 0.00000000000000000003702 99.0
TH1_k127_7805596_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 605.0
TH1_k127_7805596_30 - - - - 0.000000000000000000238 94.0
TH1_k127_7805596_31 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000001406 84.0
TH1_k127_7805596_32 Uncharacterised protein family (UPF0158) - - - 0.000000000003477 74.0
TH1_k127_7805596_33 - - - - 0.0000000002296 68.0
TH1_k127_7805596_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 543.0
TH1_k127_7805596_5 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 507.0
TH1_k127_7805596_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 487.0
TH1_k127_7805596_7 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 460.0
TH1_k127_7805596_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 396.0
TH1_k127_7805596_9 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009033 401.0
TH1_k127_7820723_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 1.082e-236 753.0
TH1_k127_7820723_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 361.0
TH1_k127_7820723_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000001377 245.0
TH1_k127_7820723_3 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000002019 213.0
TH1_k127_7820723_4 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000001011 201.0
TH1_k127_7820723_5 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000001478 170.0
TH1_k127_7820723_6 peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000009917 141.0
TH1_k127_7820723_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000001288 123.0
TH1_k127_7820723_8 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000002475 92.0
TH1_k127_7910985_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 3.074e-239 748.0
TH1_k127_7910985_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 8.371e-230 727.0
TH1_k127_7910985_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.665e-224 705.0
TH1_k127_7910985_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 464.0
TH1_k127_7910985_4 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 319.0
TH1_k127_7910985_5 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000002563 188.0
TH1_k127_7910985_6 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000001009 109.0
TH1_k127_7910985_7 TIGRFAM Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000004537 72.0
TH1_k127_7919774_0 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 539.0
TH1_k127_7919774_1 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000006704 151.0
TH1_k127_7919774_2 ABC transporter K09013 - - 0.0000000000000000000000000000000001832 136.0
TH1_k127_7919774_3 cell redox homeostasis - - - 0.000000000000000000000002938 104.0
TH1_k127_7919774_4 cell redox homeostasis K02199,K03671 - - 0.00000000000000000231 92.0
TH1_k127_7919774_5 - - - - 0.0000000001987 65.0
TH1_k127_7954108_0 UDP-N-acetylmuramyl pentapeptide K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 329.0
TH1_k127_7954108_1 Putative peptidoglycan binding domain K02450 - - 0.000000000000001539 81.0
TH1_k127_7954108_2 Type II secretion system protein B K02451 - - 0.00000000000002011 83.0
TH1_k127_7975577_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 6.79e-197 619.0
TH1_k127_7975577_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 9.385e-194 620.0
TH1_k127_7975577_10 DUF218 domain - - - 0.000000000000000000000008044 109.0
TH1_k127_7975577_11 Phosphopantetheine attachment site K02078,K14661 - - 0.0000000001142 66.0
TH1_k127_7975577_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 448.0
TH1_k127_7975577_3 PFAM Class II aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 332.0
TH1_k127_7975577_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 325.0
TH1_k127_7975577_5 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 320.0
TH1_k127_7975577_6 Male sterility protein K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002262 282.0
TH1_k127_7975577_7 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000001157 231.0
TH1_k127_7975577_8 ABC-2 type transporter K01992,K09694 - - 0.000000000000000000000000000000000000000000000000000000006157 202.0
TH1_k127_7975577_9 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000004687 160.0
TH1_k127_7989914_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 1.246e-247 777.0
TH1_k127_7989914_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 3.344e-199 634.0
TH1_k127_7989914_10 - - - - 0.00000000000000000000000001222 113.0
TH1_k127_7989914_11 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0001496 44.0
TH1_k127_7989914_12 - - - - 0.0005787 45.0
TH1_k127_7989914_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 2.481e-196 623.0
TH1_k127_7989914_3 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 475.0
TH1_k127_7989914_4 lipoprotein localization to outer membrane K02004,K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 474.0
TH1_k127_7989914_5 Citrate synthase, C-terminal domain K01647,K01659 - 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 398.0
TH1_k127_7989914_6 lipoprotein transporter activity K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 299.0
TH1_k127_7989914_7 PFAM ATP adenylyltransferase K00988 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 288.0
TH1_k127_7989914_8 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000001331 198.0
TH1_k127_7989914_9 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000003503 159.0
TH1_k127_7997203_0 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000004132 187.0
TH1_k127_7997203_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000007548 170.0
TH1_k127_7997203_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000005394 154.0
TH1_k127_7997203_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000002093 86.0
TH1_k127_7997203_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000001255 62.0
TH1_k127_7997203_5 peptidyl-tyrosine sulfation - - - 0.0006984 52.0
TH1_k127_8217625_0 Psort location Cytoplasmic, score K07137 - - 9.978e-216 680.0
TH1_k127_8217625_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 501.0
TH1_k127_8217625_10 Universal stress protein family - - - 0.0000000000000000000000000000000000002396 149.0
TH1_k127_8217625_11 proteolysis K03665 - - 0.00000000000000000000000001161 117.0
TH1_k127_8217625_12 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000007279 106.0
TH1_k127_8217625_2 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 323.0
TH1_k127_8217625_3 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 311.0
TH1_k127_8217625_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000003829 269.0
TH1_k127_8217625_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000181 257.0
TH1_k127_8217625_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000005448 256.0
TH1_k127_8217625_7 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000006201 208.0
TH1_k127_8217625_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000001248 184.0
TH1_k127_8217625_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.0000000000000000000000000000000000000000166 164.0
TH1_k127_8333016_0 Glycosyl transferase, family 2 - - - 1.932e-286 900.0
TH1_k127_8333016_1 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 452.0
TH1_k127_8333016_2 sulfuric ester hydrolase activity K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 414.0
TH1_k127_8333016_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000006049 259.0
TH1_k127_8536726_0 FAD dependent oxidoreductase K07137 - - 8.122e-243 759.0
TH1_k127_8536726_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.768e-203 640.0
TH1_k127_8536726_10 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006143 264.0
TH1_k127_8536726_11 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000004215 229.0
TH1_k127_8536726_12 ORF6N domain - - - 0.00000000000000000000000000000000000000001383 156.0
TH1_k127_8536726_13 ORF6N domain - - - 0.0001242 44.0
TH1_k127_8536726_2 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K13747 - 4.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009821 606.0
TH1_k127_8536726_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 499.0
TH1_k127_8536726_4 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 484.0
TH1_k127_8536726_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 485.0
TH1_k127_8536726_6 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 335.0
TH1_k127_8536726_7 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 308.0
TH1_k127_8536726_8 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 282.0
TH1_k127_8536726_9 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001031 271.0
TH1_k127_8544285_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 8.147e-212 663.0
TH1_k127_8544285_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 508.0
TH1_k127_8544285_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000657 197.0
TH1_k127_8544285_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000001005 148.0
TH1_k127_8563328_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 397.0
TH1_k127_8563328_1 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000008515 75.0
TH1_k127_8563328_2 Tetratricopeptide repeat - - - 0.000000002576 62.0
TH1_k127_8563328_3 - - - - 0.0000007482 53.0
TH1_k127_8570297_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 287.0
TH1_k127_8570297_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 294.0
TH1_k127_8570297_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007251 290.0
TH1_k127_8570297_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000001708 135.0
TH1_k127_8609446_0 FtsX-like permease family K02004 - - 4.887e-316 986.0
TH1_k127_8609446_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.018e-197 629.0
TH1_k127_8609446_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 502.0
TH1_k127_8609446_3 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 444.0
TH1_k127_8609446_4 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 372.0
TH1_k127_8609446_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 370.0
TH1_k127_8609446_6 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002248 284.0
TH1_k127_8609446_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000008788 199.0
TH1_k127_8609446_8 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000004146 139.0
TH1_k127_8610384_0 L,D-transpeptidase catalytic domain K16291 - - 7.631e-197 621.0
TH1_k127_8610384_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 444.0
TH1_k127_8610384_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 307.0
TH1_k127_8610384_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000005479 194.0
TH1_k127_8610384_4 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000645 174.0
TH1_k127_8610384_5 - - - - 0.000000000000000000005952 98.0
TH1_k127_8610384_6 beta-lactamase domain protein - - - 0.0000000000000001617 80.0
TH1_k127_8610384_7 Alanine-zipper, major outer membrane lipoprotein - - - 0.0000000000000936 75.0
TH1_k127_8686950_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 2.615e-212 667.0
TH1_k127_8686950_1 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 404.0
TH1_k127_8686950_10 Belongs to the UPF0296 family K09777 - - 0.000000000000000000000000001261 115.0
TH1_k127_8686950_11 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000006286 111.0
TH1_k127_8686950_12 Tetratricopeptide repeat - - - 0.00000000000000000000009421 111.0
TH1_k127_8686950_13 Psort location Cytoplasmic, score - - - 0.00000000000000000142 86.0
TH1_k127_8686950_14 Roadblock/LC7 domain - - - 0.000000000000000005823 88.0
TH1_k127_8686950_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 381.0
TH1_k127_8686950_3 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007085 279.0
TH1_k127_8686950_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000001413 243.0
TH1_k127_8686950_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000003395 208.0
TH1_k127_8686950_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000001096 204.0
TH1_k127_8686950_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000004562 178.0
TH1_k127_8686950_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000006897 173.0
TH1_k127_8686950_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000009053 155.0
TH1_k127_8711080_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 384.0
TH1_k127_8711080_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000006054 148.0
TH1_k127_8711080_2 - - - - 0.000000000000000001403 89.0
TH1_k127_8711080_3 domain protein - - - 0.000001909 56.0
TH1_k127_8725017_0 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 450.0
TH1_k127_8725017_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000111 268.0
TH1_k127_8725017_2 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003632 270.0
TH1_k127_8744811_0 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 344.0
TH1_k127_8744811_1 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 335.0
TH1_k127_8744811_2 Belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000000000000000000000006505 172.0
TH1_k127_8744811_3 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000001876 173.0
TH1_k127_8744811_4 - - - - 0.00000000000000000000000000000000000000003343 157.0
TH1_k127_8765408_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 479.0
TH1_k127_8765408_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 447.0
TH1_k127_8765408_10 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000038 169.0
TH1_k127_8765408_11 (AIR) carboxylase K06898 - - 0.000000000000000000007215 96.0
TH1_k127_8765408_12 - - - - 0.000000000000001559 80.0
TH1_k127_8765408_13 Outer membrane protein (OmpH-like) K06142 - - 0.000000000008317 72.0
TH1_k127_8765408_14 Zinc metalloprotease (Elastase) K20274 - - 0.0000003206 63.0
TH1_k127_8765408_2 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 334.0
TH1_k127_8765408_3 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 316.0
TH1_k127_8765408_4 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005867 260.0
TH1_k127_8765408_5 (Lipo)protein K04754 - - 0.0000000000000000000000000000000000000000000000000000000006744 216.0
TH1_k127_8765408_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000009079 208.0
TH1_k127_8765408_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000001001 212.0
TH1_k127_8765408_8 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000000000000004165 194.0
TH1_k127_8765408_9 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000002835 181.0
TH1_k127_8769579_0 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 422.0
TH1_k127_8769579_1 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000009152 178.0
TH1_k127_8769579_2 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000000000000000000001862 179.0
TH1_k127_8769579_3 ABC transporter, ATP-binding protein K09691 - - 0.000000000000000000000000000000001974 134.0
TH1_k127_8789466_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1632.0
TH1_k127_8789466_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 598.0
TH1_k127_8789466_10 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004153 278.0
TH1_k127_8789466_11 transcriptional regulator - - - 0.000000000000000000000001835 110.0
TH1_k127_8789466_12 Methylamine utilisation protein MauE - - - 0.00000000000000006177 87.0
TH1_k127_8789466_13 overlaps another CDS with the same product name - - - 0.00004319 48.0
TH1_k127_8789466_2 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 472.0
TH1_k127_8789466_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 424.0
TH1_k127_8789466_4 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 383.0
TH1_k127_8789466_5 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 353.0
TH1_k127_8789466_6 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 329.0
TH1_k127_8789466_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 315.0
TH1_k127_8789466_8 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 296.0
TH1_k127_8789466_9 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001759 281.0
TH1_k127_8826196_0 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 430.0
TH1_k127_8826196_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000002371 157.0
TH1_k127_8826196_2 Membrane - - - 0.0000000000000000000000623 107.0
TH1_k127_8881189_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 1.261e-215 704.0
TH1_k127_8881189_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 574.0
TH1_k127_8881189_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 443.0
TH1_k127_8881189_3 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000003688 201.0
TH1_k127_8881189_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000231 201.0
TH1_k127_8881189_5 thiamine biosynthesis protein ThiS K03154 - - 0.000000000001243 70.0
TH1_k127_8886243_0 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 375.0
TH1_k127_8886243_1 - K07071 - - 0.0000000000000000000000000002917 119.0
TH1_k127_8886243_2 - - - - 0.0000000000001234 73.0
TH1_k127_8886243_3 Belongs to the glycosyl hydrolase 26 family - - - 0.00000000001468 72.0
TH1_k127_8948004_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 578.0
TH1_k127_8948004_1 K( ) H( ) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels K11105 GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006884,GO:0008150,GO:0008324,GO:0008361,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071840,GO:0071944,GO:0090066,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.00000000000000000000000002658 109.0
TH1_k127_8948853_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 530.0
TH1_k127_8948853_1 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000009786 210.0
TH1_k127_8948853_2 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000005917 174.0
TH1_k127_8948853_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000006201 157.0
TH1_k127_8948853_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001021 131.0
TH1_k127_8949677_0 SMART Elongator protein 3 MiaB NifB - - - 9.93e-204 649.0
TH1_k127_8949677_1 Sulphur transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 440.0
TH1_k127_8949677_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 340.0
TH1_k127_8949677_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000002539 249.0
TH1_k127_8949677_5 sulfur carrier activity - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0033554,GO:0042592,GO:0048878,GO:0050896,GO:0051716,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000000000009 108.0
TH1_k127_8949677_6 Universal stress protein - - - 0.000001617 57.0
TH1_k127_897212_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 472.0
TH1_k127_897212_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 441.0
TH1_k127_897212_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000003041 261.0
TH1_k127_9070280_0 C-terminal, D2-small domain, of ClpB protein K03694 - - 1.477e-285 895.0
TH1_k127_9070280_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 487.0
TH1_k127_9070280_2 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 399.0
TH1_k127_9070280_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 411.0
TH1_k127_9070280_4 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 362.0
TH1_k127_9070280_5 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 284.0
TH1_k127_9070280_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006777 295.0
TH1_k127_9070280_7 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001312 241.0
TH1_k127_9070280_8 - - - - 0.000000000000000000000000000000000000002932 167.0
TH1_k127_9070280_9 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000004592 121.0
TH1_k127_9076853_0 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 435.0
TH1_k127_9076853_1 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000003942 190.0
TH1_k127_9076853_2 - - - - 0.0000000000000000000000000000000000000000000006454 168.0
TH1_k127_9076853_3 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000009182 158.0
TH1_k127_9076853_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000007206 137.0
TH1_k127_9076853_5 PFAM Transglycosylase-associated protein - - - 0.0000000000000000000000000000000037 129.0
TH1_k127_9076853_6 Peptidoglycan-binding LysM - - - 0.00000000000001318 75.0
TH1_k127_9103936_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 5.66e-307 964.0
TH1_k127_9103936_1 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 566.0
TH1_k127_9103936_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 497.0
TH1_k127_9103936_3 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 495.0
TH1_k127_9103936_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000000000165 160.0
TH1_k127_9103936_5 phosphatidylglycerophosphatase activity K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.000000000000000000000000000001694 126.0
TH1_k127_9103936_6 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000000000000000002217 119.0
TH1_k127_9103936_7 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.0000000000000000000000007698 107.0
TH1_k127_9103936_8 ATP synthase, subunit b - - - 0.000000061 58.0
TH1_k127_9103936_9 Modulates RecA activity K03565 - - 0.00000007498 60.0
TH1_k127_9516614_0 nodulation K00612 - - 9.157e-263 822.0
TH1_k127_9516614_1 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 519.0
TH1_k127_9516614_10 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000006644 224.0
TH1_k127_9516614_11 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000001209 213.0
TH1_k127_9516614_12 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000001139 199.0
TH1_k127_9516614_13 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000002373 188.0
TH1_k127_9516614_14 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000003996 164.0
TH1_k127_9516614_15 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.000000000000000001491 97.0
TH1_k127_9516614_16 PFAM Sulfotransferase domain - - - 0.00000000000000007083 90.0
TH1_k127_9516614_17 - - - - 0.00000000000001689 74.0
TH1_k127_9516614_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 402.0
TH1_k127_9516614_3 Domain of unknown function (DUF3413) K07014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 376.0
TH1_k127_9516614_4 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 287.0
TH1_k127_9516614_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005686 280.0
TH1_k127_9516614_6 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001439 281.0
TH1_k127_9516614_7 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003751 271.0
TH1_k127_9516614_8 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002767 237.0
TH1_k127_9516614_9 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000001993 226.0
TH1_k127_9519079_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.615e-297 932.0
TH1_k127_9519079_1 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 312.0
TH1_k127_9519079_2 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000004696 117.0
TH1_k127_9519079_3 Haemolysin-type calcium-binding - - - 0.00000000000000000002376 106.0
TH1_k127_9519079_4 manually curated - - - 0.000000001233 61.0
TH1_k127_9686012_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1101.0
TH1_k127_9686012_1 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 505.0
TH1_k127_9686012_2 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 301.0
TH1_k127_9686012_3 response regulator - - - 0.0000000000000000000000000000000141 139.0
TH1_k127_9686012_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000001075 70.0