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Overview

ID MAG03854
Name TH1_bin.22
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family
Genus
Species
Assembly information
Completeness (%) 96.93
Contamination (%) 1.79
GC content (%) 58.0
N50 (bp) 12,352
Genome size (bp) 2,381,700

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2238

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_1180431_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 578.0
TH1_k127_1180431_1 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 467.0
TH1_k127_1180431_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 357.0
TH1_k127_1180431_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000007184 207.0
TH1_k127_120588_0 Protein conserved in bacteria - - - 3.242e-242 774.0
TH1_k127_120588_1 sister chromatid segregation - - - 1.664e-202 643.0
TH1_k127_120588_10 lactate metabolic process K11473,K18928 - - 0.000000000000000000000000000000000000000000000000000000000000293 228.0
TH1_k127_120588_11 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000007846 207.0
TH1_k127_120588_12 metal cluster binding K06940 - - 0.00000000000000000000000000000000000000000000000004709 187.0
TH1_k127_120588_13 HEAT repeats - - - 0.0000000000000000000000000000000000000000000001134 188.0
TH1_k127_120588_14 Diadenylate cyclase - - - 0.0000000000000000000000000000000000000000001767 170.0
TH1_k127_120588_15 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000006375 127.0
TH1_k127_120588_16 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000007044 123.0
TH1_k127_120588_17 epimerase dehydratase K19997 - 5.1.3.26 0.000000000004215 73.0
TH1_k127_120588_18 Putative prokaryotic signal transducing protein - - - 0.0001808 48.0
TH1_k127_120588_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 589.0
TH1_k127_120588_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 481.0
TH1_k127_120588_4 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 315.0
TH1_k127_120588_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 326.0
TH1_k127_120588_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 313.0
TH1_k127_120588_7 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002025 265.0
TH1_k127_120588_8 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002314 265.0
TH1_k127_120588_9 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001637 248.0
TH1_k127_1217799_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.449e-198 638.0
TH1_k127_1217799_1 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 584.0
TH1_k127_1217799_10 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000002889 186.0
TH1_k127_1217799_11 translation release factor activity - - - 0.00000000000000000000000000000000000000001236 158.0
TH1_k127_1217799_12 PFAM conserved K08316 - 2.1.1.171 0.000000000000000000000000000002638 128.0
TH1_k127_1217799_13 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.00000000000000000000000000001049 121.0
TH1_k127_1217799_14 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000002775 123.0
TH1_k127_1217799_15 part of a sulfur-relay system K11179 - - 0.00000000000000000000000001051 111.0
TH1_k127_1217799_16 Psort location Cytoplasmic, score - - - 0.0000000000001611 83.0
TH1_k127_1217799_17 - - - - 0.000000000006412 74.0
TH1_k127_1217799_18 Transglycosylase SLT domain - - - 0.0000000003192 69.0
TH1_k127_1217799_2 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 517.0
TH1_k127_1217799_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 462.0
TH1_k127_1217799_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 416.0
TH1_k127_1217799_5 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 401.0
TH1_k127_1217799_6 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 394.0
TH1_k127_1217799_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 327.0
TH1_k127_1217799_8 metal-dependent phosphohydrolase HD region K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 280.0
TH1_k127_1217799_9 PFAM Isochorismatase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000006262 209.0
TH1_k127_1228724_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1238.0
TH1_k127_1228724_1 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001697 254.0
TH1_k127_1228724_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000003333 216.0
TH1_k127_1228724_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000001187 188.0
TH1_k127_1228724_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000002057 140.0
TH1_k127_1241554_0 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 327.0
TH1_k127_1241554_1 Protein of unknown function (DUF3011) - - - 0.00000000000000000000000000000000000000000000000000000006854 207.0
TH1_k127_1241554_2 part of a sulfur-relay system K11179 - - 0.0000000000000000000000002799 109.0
TH1_k127_1241554_3 Sigma-54 interaction domain - - - 0.0000002628 55.0
TH1_k127_1241554_5 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000229 51.0
TH1_k127_1250585_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1471.0
TH1_k127_1250585_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 387.0
TH1_k127_1250585_2 Ferredoxin-type protein, NapH MauN family K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 353.0
TH1_k127_1250585_3 TIGRFAM MauM NapG family ferredoxin-type protein K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 318.0
TH1_k127_1250585_4 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.0000000000000000000000000000000000000000825 158.0
TH1_k127_1250585_5 negative regulation of establishment of protein localization K02570 GO:0003674,GO:0005048,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032879,GO:0032880,GO:0033218,GO:0042277,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0051049,GO:0051051,GO:0051223,GO:0051224,GO:0065007,GO:0070201,GO:0090087,GO:1904950 - 0.0000000000000000000007793 97.0
TH1_k127_1272360_0 PFAM amino acid permease-associated region K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 549.0
TH1_k127_1272360_1 Aminotransferase K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 497.0
TH1_k127_1272360_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K07003 - - 0.0000000000000000000000000000755 124.0
TH1_k127_1272360_2 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 389.0
TH1_k127_1272360_3 citrate synthase K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 393.0
TH1_k127_1272360_4 Natural resistance-associated macrophage protein K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 324.0
TH1_k127_1272360_5 NosL - - - 0.0000000000000000000000000000000000000000009382 163.0
TH1_k127_1272360_6 PFAM pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000008155 149.0
TH1_k127_1272360_7 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000005742 145.0
TH1_k127_1272360_8 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03774,K03775 - 5.2.1.8 0.000000000000000000000000000000000008047 144.0
TH1_k127_1272360_9 Membrane - - - 0.0000000000000000000000000000000001175 137.0
TH1_k127_1281732_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1418.0
TH1_k127_1281732_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 468.0
TH1_k127_1281732_10 Protein of unknown function (DUF2892) - - - 0.0000000000000000000001063 100.0
TH1_k127_1281732_11 Membrane - - - 0.00000000000000000004888 95.0
TH1_k127_1281732_12 PFAM translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000472 81.0
TH1_k127_1281732_13 transcriptional regulator K03892 - - 0.00000000000000359 81.0
TH1_k127_1281732_2 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 390.0
TH1_k127_1281732_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 355.0
TH1_k127_1281732_4 PFAM tRNA pseudouridine synthase D TruD K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 309.0
TH1_k127_1281732_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006107 280.0
TH1_k127_1281732_6 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005137 259.0
TH1_k127_1281732_7 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000374 269.0
TH1_k127_1281732_8 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000006137 154.0
TH1_k127_1281732_9 - - - - 0.0000000000000000000000000001875 118.0
TH1_k127_1287989_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 3.063e-275 854.0
TH1_k127_1287989_1 ribonuclease activity - - - 0.0000000000000000000000432 104.0
TH1_k127_1287989_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000001156 106.0
TH1_k127_1287989_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000009335 94.0
TH1_k127_1287989_4 PIN domain - - - 0.00000000000000000001075 96.0
TH1_k127_1287989_5 SpoVT / AbrB like domain - - - 0.000000000000005324 78.0
TH1_k127_1287989_6 SpoVT / AbrB like domain - - - 0.0000000003441 64.0
TH1_k127_1287989_7 Bacterial antitoxin of type II TA system, VapB - - - 0.0003695 46.0
TH1_k127_1291208_0 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 2.019e-238 746.0
TH1_k127_1291208_1 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000005522 101.0
TH1_k127_1297994_0 PD-(D/E)XK nuclease superfamily - - - 2.555e-217 710.0
TH1_k127_1297994_1 Belongs to the helicase family. UvrD subfamily - - - 1.599e-206 676.0
TH1_k127_1297994_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 419.0
TH1_k127_1297994_3 Peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 328.0
TH1_k127_1297994_4 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005941 285.0
TH1_k127_1297994_5 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000002425 219.0
TH1_k127_1297994_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000002604 166.0
TH1_k127_1299884_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 599.0
TH1_k127_1299884_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 537.0
TH1_k127_1299884_10 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000006041 187.0
TH1_k127_1299884_11 metal cluster binding K06940,K18475 - - 0.00000000000000000000000000000000004757 147.0
TH1_k127_1299884_12 Cytochrome c - - - 0.000000000000000000000000000009824 125.0
TH1_k127_1299884_13 Domain of unknown function (DUF1738) - - - 0.00000000000000001796 84.0
TH1_k127_1299884_14 Domain of unknown function (DUF1738) - - - 0.0000001635 57.0
TH1_k127_1299884_2 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 415.0
TH1_k127_1299884_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 348.0
TH1_k127_1299884_4 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 319.0
TH1_k127_1299884_5 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 302.0
TH1_k127_1299884_6 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001667 251.0
TH1_k127_1299884_7 Asparaginase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000369 239.0
TH1_k127_1299884_8 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000001193 214.0
TH1_k127_1299884_9 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000001433 213.0
TH1_k127_1300498_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.144e-319 994.0
TH1_k127_1300498_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.58e-234 732.0
TH1_k127_1300498_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 431.0
TH1_k127_1300498_3 PFAM Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003899 277.0
TH1_k127_1300498_4 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000001759 162.0
TH1_k127_1300498_5 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000004058 131.0
TH1_k127_1300498_6 - - - - 0.0000001214 55.0
TH1_k127_1338722_0 FAD binding domain K00394 - 1.8.99.2 7.85e-321 987.0
TH1_k127_1338722_1 PUA-like domain K00958 - 2.7.7.4 3.629e-204 643.0
TH1_k127_1338722_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 364.0
TH1_k127_1338722_3 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002152 254.0
TH1_k127_1338722_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000003419 217.0
TH1_k127_1338722_5 - - - - 0.00000000000000000000000000000000001939 137.0
TH1_k127_1338722_6 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000001105 55.0
TH1_k127_1338722_7 RNA-directed DNA polymerase (reverse transcriptase) K00986 - 2.7.7.49 0.000002829 53.0
TH1_k127_1349369_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 490.0
TH1_k127_1349369_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 427.0
TH1_k127_1349369_2 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 361.0
TH1_k127_1349369_3 PINc domain ribonuclease K09006 - - 0.0000000000000000000000000000000000000000000000000000000000000005713 230.0
TH1_k127_1349369_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000007496 172.0
TH1_k127_1349369_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000004756 127.0
TH1_k127_1349369_6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000008882 124.0
TH1_k127_1357188_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 597.0
TH1_k127_1357188_1 DNA polymerase A domain K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 301.0
TH1_k127_1357188_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000003058 192.0
TH1_k127_1357188_3 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000009653 160.0
TH1_k127_1357188_4 Transposase - - - 0.0000000000000000000004974 100.0
TH1_k127_1357188_5 PFAM transposase IS4 family protein - - - 0.00000001373 58.0
TH1_k127_1366056_0 UPF0210 protein K09157 - - 5.188e-216 680.0
TH1_k127_1366056_1 PFAM amino acid-binding ACT domain protein K03567 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008658 246.0
TH1_k127_1366056_2 META domain - - - 0.00000000000000000000000000000000000000000000000000000006032 206.0
TH1_k127_1366056_3 Nitroreductase family - - - 0.0000000000000000000000000000000001271 139.0
TH1_k127_1366056_4 Dodecin K09165 - - 0.0000000000000000000001896 98.0
TH1_k127_1405116_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 388.0
TH1_k127_1405116_1 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 294.0
TH1_k127_1405116_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005386 267.0
TH1_k127_1405116_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000001508 175.0
TH1_k127_142774_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 5.962e-241 759.0
TH1_k127_142774_1 PFAM magnesium chelatase ChlI subunit K07391 - - 1.671e-209 662.0
TH1_k127_142774_2 Fructose-bisphosphate aldolase class-II - - - 5.223e-209 657.0
TH1_k127_142774_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 3.231e-201 636.0
TH1_k127_142774_4 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 513.0
TH1_k127_142774_5 citrate synthase K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 395.0
TH1_k127_142774_6 radical SAM protein K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001586 284.0
TH1_k127_142774_7 MreB/Mbl protein K03569 - - 0.0000000000000000000000000000000000000000003155 163.0
TH1_k127_142774_8 acetyltransferase - - - 0.00000000000000000000000000000000001744 140.0
TH1_k127_142774_9 CAAX protease self-immunity - - - 0.0000000007867 67.0
TH1_k127_1471298_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.338e-232 730.0
TH1_k127_1471298_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 7.966e-196 618.0
TH1_k127_1471298_10 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000002016 192.0
TH1_k127_1471298_11 Glycosyltransferase, group 1 family protein - - - 0.00000000000000000000000000000000000000000004551 178.0
TH1_k127_1471298_12 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000772 173.0
TH1_k127_1471298_13 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000005843 148.0
TH1_k127_1471298_14 methyltransferase - - - 0.0000000000000000000004976 107.0
TH1_k127_1471298_16 Uncharacterised nucleotidyltransferase - - - 0.000000002026 69.0
TH1_k127_1471298_17 O-Antigen ligase - - - 0.00000001469 67.0
TH1_k127_1471298_2 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 605.0
TH1_k127_1471298_3 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 565.0
TH1_k127_1471298_4 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 534.0
TH1_k127_1471298_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 524.0
TH1_k127_1471298_6 glycogen (starch) synthase activity K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 379.0
TH1_k127_1471298_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006346 256.0
TH1_k127_1471298_8 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001189 229.0
TH1_k127_1471298_9 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000002358 216.0
TH1_k127_1503228_0 Protein of unknown function (DUF2867) - - - 2.545e-196 622.0
TH1_k127_1503228_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 568.0
TH1_k127_1503228_2 PFAM Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 460.0
TH1_k127_1503228_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000959 346.0
TH1_k127_1503228_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000001771 266.0
TH1_k127_1503228_5 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001208 241.0
TH1_k127_1503228_6 - - - - 0.0000000000000000000000000000000000000000000000000001242 192.0
TH1_k127_1503228_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000001405 169.0
TH1_k127_1503228_8 - - - - 0.0000000000000000000000000000000000000000005169 164.0
TH1_k127_1503228_9 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000762 140.0
TH1_k127_1551259_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 604.0
TH1_k127_1551259_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 521.0
TH1_k127_1551259_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 377.0
TH1_k127_1551259_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 366.0
TH1_k127_1551259_4 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000005882 246.0
TH1_k127_1551259_5 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000004084 199.0
TH1_k127_1551259_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000003632 198.0
TH1_k127_1555751_0 Glycosyl hydrolase family 57 - - - 3.459e-207 649.0
TH1_k127_1555751_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001558 278.0
TH1_k127_1555751_2 Haemolytic - - - 0.00000000000000000002764 97.0
TH1_k127_1555751_3 - - - - 0.00000000006706 70.0
TH1_k127_1555751_5 - - - - 0.0001368 47.0
TH1_k127_1559558_0 Elongation factor G, domain IV K02355 - - 7.187e-319 989.0
TH1_k127_1559558_1 pyruvate-flavodoxin oxidoreductase activity - - - 5.099e-304 940.0
TH1_k127_1559558_10 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 509.0
TH1_k127_1559558_11 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 507.0
TH1_k127_1559558_12 AIR synthase related protein, N-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 407.0
TH1_k127_1559558_13 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 359.0
TH1_k127_1559558_14 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 323.0
TH1_k127_1559558_15 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 291.0
TH1_k127_1559558_16 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003372 287.0
TH1_k127_1559558_17 Peptidase T-like protein K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001269 282.0
TH1_k127_1559558_18 Histidine kinase K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002169 276.0
TH1_k127_1559558_19 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000005457 248.0
TH1_k127_1559558_2 Belongs to the glycosyl hydrolase 57 family - - - 4.174e-300 941.0
TH1_k127_1559558_20 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000002774 231.0
TH1_k127_1559558_21 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000003194 232.0
TH1_k127_1559558_22 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000007458 184.0
TH1_k127_1559558_23 HNH nucleases - - - 0.000000000000000000000000000000000000000000001505 167.0
TH1_k127_1559558_24 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000003023 170.0
TH1_k127_1559558_26 ThiS family K03636 - - 0.00000000000000000000000000000000001683 137.0
TH1_k127_1559558_28 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000367 127.0
TH1_k127_1559558_29 Protein of unknown function (DUF2799) - - - 0.000000000000000000000000000001811 130.0
TH1_k127_1559558_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.659e-251 785.0
TH1_k127_1559558_30 NIL - - - 0.00000000000000000000000000003117 118.0
TH1_k127_1559558_31 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000004954 122.0
TH1_k127_1559558_32 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000001568 115.0
TH1_k127_1559558_33 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.000000000000000000000007139 106.0
TH1_k127_1559558_34 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000000000000119 91.0
TH1_k127_1559558_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.118e-246 772.0
TH1_k127_1559558_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 596.0
TH1_k127_1559558_6 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 585.0
TH1_k127_1559558_7 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 576.0
TH1_k127_1559558_8 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 578.0
TH1_k127_1559558_9 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 550.0
TH1_k127_1615926_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 5.209e-297 934.0
TH1_k127_1615926_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 9.832e-277 870.0
TH1_k127_1615926_2 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.15e-262 822.0
TH1_k127_1615926_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 304.0
TH1_k127_1615926_4 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006073 279.0
TH1_k127_1615926_5 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001287 241.0
TH1_k127_1615926_6 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567,K10778 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000000000000001954 139.0
TH1_k127_1615926_7 Transcriptional regulator, MerR family - - - 0.00000000000000000000000000000006044 130.0
TH1_k127_1615926_8 - - - - 0.0000009203 57.0
TH1_k127_1623525_0 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 292.0
TH1_k127_1623525_1 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000008638 210.0
TH1_k127_1623525_2 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000008202 181.0
TH1_k127_1623525_3 Glycosyltransferase, group 2 family protein - - - 0.00000000000000000000000000000000297 138.0
TH1_k127_1623525_4 PFAM Fimbrial assembly K02461 - - 0.0000000000000000000000006398 120.0
TH1_k127_1623525_5 pilus assembly protein PilW K02459,K02672 - - 0.00000000008827 71.0
TH1_k127_1623525_6 COG4970 Tfp pilus assembly protein FimT K02457 - - 0.0000003119 59.0
TH1_k127_1623525_7 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.00000296 56.0
TH1_k127_1623525_8 type IV pilus modification protein PilV K02458 - - 0.0004084 48.0
TH1_k127_1637024_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 479.0
TH1_k127_1637024_1 PHB de-polymerase C-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 434.0
TH1_k127_1637024_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 425.0
TH1_k127_1637024_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 340.0
TH1_k127_1637024_4 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000000000000000000206 153.0
TH1_k127_1637024_5 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000006355 52.0
TH1_k127_1650575_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 492.0
TH1_k127_1650575_1 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001648 275.0
TH1_k127_1650575_2 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005811 246.0
TH1_k127_1650575_3 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000003358 197.0
TH1_k127_1650575_4 PFAM ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000002212 190.0
TH1_k127_1650575_5 HDOD domain - - - 0.000000000000000000005041 106.0
TH1_k127_1650575_6 Histidine kinase - - - 0.000001072 61.0
TH1_k127_1664544_0 FAD binding domain K00278 - 1.4.3.16 1.235e-202 643.0
TH1_k127_1664544_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 578.0
TH1_k127_1664544_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 304.0
TH1_k127_1664544_11 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 299.0
TH1_k127_1664544_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 289.0
TH1_k127_1664544_13 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004419 274.0
TH1_k127_1664544_14 Cytochrome b/b6/petB K03887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001319 273.0
TH1_k127_1664544_15 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000663 261.0
TH1_k127_1664544_16 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000007742 255.0
TH1_k127_1664544_17 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000008189 249.0
TH1_k127_1664544_18 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000001241 245.0
TH1_k127_1664544_19 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000008359 217.0
TH1_k127_1664544_2 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 525.0
TH1_k127_1664544_20 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000003374 166.0
TH1_k127_1664544_21 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.000000000000000000000000000000000000000002116 162.0
TH1_k127_1664544_22 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000006824 158.0
TH1_k127_1664544_23 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000138 112.0
TH1_k127_1664544_24 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000002175 118.0
TH1_k127_1664544_25 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000003399 110.0
TH1_k127_1664544_26 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000001813 112.0
TH1_k127_1664544_27 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000006005 111.0
TH1_k127_1664544_29 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000007869 71.0
TH1_k127_1664544_3 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 504.0
TH1_k127_1664544_30 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000001757 61.0
TH1_k127_1664544_31 PFAM regulatory protein AsnC Lrp family - - - 0.00000005281 59.0
TH1_k127_1664544_4 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 494.0
TH1_k127_1664544_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 473.0
TH1_k127_1664544_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 453.0
TH1_k127_1664544_7 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 426.0
TH1_k127_1664544_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 360.0
TH1_k127_1664544_9 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 308.0
TH1_k127_1668670_0 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 548.0
TH1_k127_1668670_1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 407.0
TH1_k127_1668670_2 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 347.0
TH1_k127_1668670_3 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001201 252.0
TH1_k127_1668670_4 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000006734 201.0
TH1_k127_1690430_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 327.0
TH1_k127_1690430_1 energy transducer activity K03832 - - 0.00000000000000000000000000000000000000000000004907 180.0
TH1_k127_1690430_2 Pas domain s-box - - - 0.000000000000000000000000000000000005726 157.0
TH1_k127_1690430_3 - - - - 0.0000000000000000000000000000484 117.0
TH1_k127_1690430_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000008195 124.0
TH1_k127_1690430_5 Bacterial Ig-like domain (group 1) - - - 0.0000005021 62.0
TH1_k127_172783_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 1.077e-205 656.0
TH1_k127_172783_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 528.0
TH1_k127_172783_10 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000275 254.0
TH1_k127_172783_11 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000000007848 209.0
TH1_k127_172783_12 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000000002861 203.0
TH1_k127_172783_13 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000001486 114.0
TH1_k127_172783_16 Regulatory protein, FmdB family - - - 0.00000004477 57.0
TH1_k127_172783_2 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 457.0
TH1_k127_172783_3 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 390.0
TH1_k127_172783_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 350.0
TH1_k127_172783_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 351.0
TH1_k127_172783_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 313.0
TH1_k127_172783_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 294.0
TH1_k127_172783_8 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 293.0
TH1_k127_172783_9 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001582 284.0
TH1_k127_1780163_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 537.0
TH1_k127_1780163_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 523.0
TH1_k127_1780163_10 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000004981 127.0
TH1_k127_1780163_12 Major Facilitator Superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000002407 104.0
TH1_k127_1780163_13 Cytochrome c - - - 0.0000000000004655 79.0
TH1_k127_1780163_2 PFAM Radical SAM domain protein K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 421.0
TH1_k127_1780163_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 409.0
TH1_k127_1780163_4 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 400.0
TH1_k127_1780163_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 341.0
TH1_k127_1780163_6 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 338.0
TH1_k127_1780163_7 smart pdz dhr glgf - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001676 292.0
TH1_k127_1780163_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000001176 233.0
TH1_k127_1831941_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 3.962e-207 650.0
TH1_k127_1831941_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 511.0
TH1_k127_1831941_2 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 499.0
TH1_k127_1831941_3 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 401.0
TH1_k127_1831941_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 302.0
TH1_k127_1831941_5 Belongs to the acetokinase family K00929 - 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000001152 272.0
TH1_k127_1831941_6 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000002241 235.0
TH1_k127_1831941_7 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000001321 201.0
TH1_k127_1831941_8 acetyltransferase - - - 0.000000000000000000000001976 110.0
TH1_k127_1850855_0 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007256 296.0
TH1_k127_1850855_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005201 245.0
TH1_k127_1850855_2 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000000009437 171.0
TH1_k127_1850855_3 - - - - 0.00000000000000000006977 97.0
TH1_k127_186309_0 Domains REC, sigma54 interaction, HTH8 K02481 - - 9.883e-199 629.0
TH1_k127_186309_1 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 548.0
TH1_k127_186309_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 508.0
TH1_k127_186309_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 336.0
TH1_k127_186309_4 VanZ like family - - - 0.000000000000000006565 88.0
TH1_k127_1881431_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 454.0
TH1_k127_1881431_1 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 396.0
TH1_k127_1881431_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000002445 190.0
TH1_k127_1881431_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000009185 113.0
TH1_k127_1885138_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 4.259e-215 674.0
TH1_k127_1885138_1 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 6.159e-200 633.0
TH1_k127_1885138_10 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008823 263.0
TH1_k127_1885138_11 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.00000000000000000000000000000000000000000000000000000000000005551 219.0
TH1_k127_1885138_12 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000003211 212.0
TH1_k127_1885138_13 amino acid-binding ACT - - - 0.00000000000000000000000000000000000000000000000000000004458 200.0
TH1_k127_1885138_14 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000001641 197.0
TH1_k127_1885138_15 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000002272 166.0
TH1_k127_1885138_16 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000009568 151.0
TH1_k127_1885138_17 - - - - 0.00000000000000000000000000000000000000595 150.0
TH1_k127_1885138_18 integrase domain protein SAM domain protein K04763 - - 0.0000000000000000000000000001969 129.0
TH1_k127_1885138_19 His Kinase A (phosphoacceptor) domain - - - 0.0003889 50.0
TH1_k127_1885138_2 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 1.114e-198 639.0
TH1_k127_1885138_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 598.0
TH1_k127_1885138_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 479.0
TH1_k127_1885138_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 463.0
TH1_k127_1885138_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 404.0
TH1_k127_1885138_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 354.0
TH1_k127_1885138_8 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 340.0
TH1_k127_1885138_9 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007767 272.0
TH1_k127_1958632_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 591.0
TH1_k127_1958632_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 596.0
TH1_k127_1958632_10 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 340.0
TH1_k127_1958632_11 Belongs to the MurCDEF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 321.0
TH1_k127_1958632_12 PFAM Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000003768 160.0
TH1_k127_1958632_13 iron-sulfur cluster assembly - - - 0.00000000000000000000006465 103.0
TH1_k127_1958632_2 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 585.0
TH1_k127_1958632_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 527.0
TH1_k127_1958632_4 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 484.0
TH1_k127_1958632_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 399.0
TH1_k127_1958632_6 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 372.0
TH1_k127_1958632_7 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 361.0
TH1_k127_1958632_8 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 346.0
TH1_k127_1958632_9 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 346.0
TH1_k127_2005531_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 0.0 1140.0
TH1_k127_2005531_1 Aconitase C-terminal domain K01681 - 4.2.1.3 1.256e-287 895.0
TH1_k127_2005531_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 562.0
TH1_k127_2005531_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 472.0
TH1_k127_2005531_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 346.0
TH1_k127_2005531_5 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000954 246.0
TH1_k127_2005531_6 Thioredoxin-like - - - 0.00000000000000000000000000000000004537 148.0
TH1_k127_2005531_7 regulation of translation K03530 - - 0.0000000000000000000000000000004831 124.0
TH1_k127_2005531_8 Helix-turn-helix domain protein - - - 0.000000000000000000000000001072 118.0
TH1_k127_2005531_9 Alternative locus ID - - - 0.00000000004445 66.0
TH1_k127_207758_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.208e-295 923.0
TH1_k127_207758_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.405e-203 643.0
TH1_k127_207758_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000009648 205.0
TH1_k127_207758_11 3-dehydroquinate dehydratase activity K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000004087 177.0
TH1_k127_207758_12 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002747 130.0
TH1_k127_207758_13 COG0008 Glutamyl- and glutaminyl-tRNA synthetases K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 0.000000000000000000000000000006397 120.0
TH1_k127_207758_14 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00000000000000000000000004648 108.0
TH1_k127_207758_15 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000000000001561 95.0
TH1_k127_207758_16 Belongs to the UPF0434 family K09791 - - 0.000000000000000007832 84.0
TH1_k127_207758_17 Cupin 2, conserved barrel domain protein - - - 0.0000000000001773 74.0
TH1_k127_207758_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 523.0
TH1_k127_207758_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008444 510.0
TH1_k127_207758_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 435.0
TH1_k127_207758_5 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 423.0
TH1_k127_207758_6 Chromate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 417.0
TH1_k127_207758_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 368.0
TH1_k127_207758_8 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 360.0
TH1_k127_207758_9 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001747 245.0
TH1_k127_217310_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 363.0
TH1_k127_217310_1 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 342.0
TH1_k127_217310_2 denitrification pathway - - - 0.00000000000000000000001429 107.0
TH1_k127_217310_3 PFAM cytochrome c class III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000001305 57.0
TH1_k127_2199715_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 3.031e-287 893.0
TH1_k127_2199715_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 482.0
TH1_k127_2199715_2 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000001674 172.0
TH1_k127_2199715_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000001383 149.0
TH1_k127_220526_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 317.0
TH1_k127_220526_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000001407 193.0
TH1_k127_220526_2 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.000000000000003534 80.0
TH1_k127_224431_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 398.0
TH1_k127_224431_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 317.0
TH1_k127_224431_2 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 312.0
TH1_k127_224431_3 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002895 235.0
TH1_k127_224431_4 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000642 231.0
TH1_k127_224431_5 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000005261 165.0
TH1_k127_224431_6 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000000000001338 154.0
TH1_k127_2355843_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.463e-250 784.0
TH1_k127_2434326_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 434.0
TH1_k127_2434326_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000004294 228.0
TH1_k127_2434326_2 EamA-like transporter family - - - 0.000004675 49.0
TH1_k127_2441995_0 PFAM nickel-dependent hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 611.0
TH1_k127_2441995_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 532.0
TH1_k127_2441995_10 PFAM regulatory protein, LysR - - - 0.0000000000000000000000176 108.0
TH1_k127_2441995_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 416.0
TH1_k127_2441995_3 NADH-quinone oxidoreductase K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 335.0
TH1_k127_2441995_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002181 275.0
TH1_k127_2441995_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000006288 198.0
TH1_k127_2441995_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000476 149.0
TH1_k127_2441995_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000211 140.0
TH1_k127_2441995_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000001739 139.0
TH1_k127_2441995_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000003883 113.0
TH1_k127_2450027_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1236.0
TH1_k127_2450027_1 PFAM Radical SAM - - - 7.719e-207 653.0
TH1_k127_2450027_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 394.0
TH1_k127_2450027_11 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 376.0
TH1_k127_2450027_12 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 348.0
TH1_k127_2450027_13 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 316.0
TH1_k127_2450027_14 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 309.0
TH1_k127_2450027_15 PFAM WD40 repeat, subgroup - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001694 264.0
TH1_k127_2450027_16 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000001369 233.0
TH1_k127_2450027_17 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000004893 227.0
TH1_k127_2450027_18 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000000005764 197.0
TH1_k127_2450027_19 LemA family K03744 - - 0.000000000000000000000000000000000000000000000005292 179.0
TH1_k127_2450027_2 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 602.0
TH1_k127_2450027_20 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000001768 141.0
TH1_k127_2450027_21 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000002972 118.0
TH1_k127_2450027_22 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000000000000001231 98.0
TH1_k127_2450027_23 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000001196 85.0
TH1_k127_2450027_24 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000003666 59.0
TH1_k127_2450027_25 - - - - 0.00007712 55.0
TH1_k127_2450027_3 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 479.0
TH1_k127_2450027_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 463.0
TH1_k127_2450027_5 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 428.0
TH1_k127_2450027_6 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 433.0
TH1_k127_2450027_7 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 407.0
TH1_k127_2450027_8 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 418.0
TH1_k127_2450027_9 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 408.0
TH1_k127_2454611_0 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 574.0
TH1_k127_2454611_1 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 355.0
TH1_k127_2454611_2 Protein of unknown function (DUF2934) - - - 0.0000001017 57.0
TH1_k127_2454611_3 electron transfer activity K00428 - 1.11.1.5 0.0000007504 55.0
TH1_k127_2479483_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 2.948e-275 859.0
TH1_k127_2479483_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 2.661e-212 681.0
TH1_k127_2479483_10 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000002286 225.0
TH1_k127_2479483_11 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000005888 147.0
TH1_k127_2479483_12 PFAM RES domain - - - 0.0000000000000000000000000000000001265 138.0
TH1_k127_2479483_13 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000003156 105.0
TH1_k127_2479483_15 STAS domain K04749 - - 0.00000000000000002493 87.0
TH1_k127_2479483_16 Protein of unknown function (DUF2384) - - - 0.0000000000000001123 87.0
TH1_k127_2479483_17 PFAM Mammalian cell entry related K02067 - - 0.000000000000003073 86.0
TH1_k127_2479483_18 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0009782 49.0
TH1_k127_2479483_2 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 462.0
TH1_k127_2479483_3 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 362.0
TH1_k127_2479483_4 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 315.0
TH1_k127_2479483_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 293.0
TH1_k127_2479483_6 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006501 282.0
TH1_k127_2479483_7 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001719 268.0
TH1_k127_2479483_8 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001958 253.0
TH1_k127_2479483_9 Stage II sporulation protein E (SpoIIE) - - - 0.0000000000000000000000000000000000000000000000000000000000000001093 237.0
TH1_k127_2481344_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 5e-323 1012.0
TH1_k127_2481344_1 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 580.0
TH1_k127_2481344_10 Modulates RecA activity K03565 - - 0.00007111 51.0
TH1_k127_2481344_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 535.0
TH1_k127_2481344_3 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000006263 214.0
TH1_k127_2481344_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.0000000000000000000000000000000000000000000000000000002463 198.0
TH1_k127_2481344_5 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000393 196.0
TH1_k127_2481344_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000000000003443 158.0
TH1_k127_2481344_7 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000179 126.0
TH1_k127_2481344_8 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.0000000000000000000000000165 115.0
TH1_k127_2481344_9 - - - - 0.00000000000738 72.0
TH1_k127_2499664_0 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 602.0
TH1_k127_2499664_1 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 541.0
TH1_k127_2499664_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 439.0
TH1_k127_2499664_3 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 410.0
TH1_k127_2499664_4 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 336.0
TH1_k127_2499664_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000001676 214.0
TH1_k127_2499664_6 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000004924 181.0
TH1_k127_2499664_7 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000007716 165.0
TH1_k127_2499664_8 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000235 124.0
TH1_k127_2516594_0 HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006041 247.0
TH1_k127_2516594_1 Multi-sensor signal transduction multi-kinase - - - 0.00000000000000000000000000000000000000000000000000000000000077 235.0
TH1_k127_2516594_2 electron transfer activity K02305,K08738 - - 0.0000000000000000000000000000000000000000000000000000000001092 209.0
TH1_k127_2516594_3 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000001539 184.0
TH1_k127_2516594_4 PFAM major facilitator superfamily MFS_1 - - - 0.00000009362 55.0
TH1_k127_2516594_5 Diguanylate cyclase - - - 0.0000001274 65.0
TH1_k127_2518048_0 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 460.0
TH1_k127_2518048_1 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 447.0
TH1_k127_2518048_10 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000004577 192.0
TH1_k127_2518048_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000007775 184.0
TH1_k127_2518048_12 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000003839 168.0
TH1_k127_2518048_13 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000004454 166.0
TH1_k127_2518048_14 SMART Cold shock protein K03704 - - 0.000000000000000000000000003203 111.0
TH1_k127_2518048_15 rubredoxin - - - 0.00000000000000000000000173 102.0
TH1_k127_2518048_17 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000008689 80.0
TH1_k127_2518048_19 - - - - 0.0000000002832 64.0
TH1_k127_2518048_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 441.0
TH1_k127_2518048_20 Aspartyl protease K06985 - - 0.0006705 49.0
TH1_k127_2518048_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 422.0
TH1_k127_2518048_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 346.0
TH1_k127_2518048_5 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 332.0
TH1_k127_2518048_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 308.0
TH1_k127_2518048_7 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004541 253.0
TH1_k127_2518048_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000001526 240.0
TH1_k127_2518048_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001505 227.0
TH1_k127_2533182_0 TIGRFAM DNA polymerase III, alpha subunit K02337,K14162 - 2.7.7.7 0.0 1038.0
TH1_k127_2533182_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 9.04e-321 1000.0
TH1_k127_2533182_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000002096 220.0
TH1_k127_2533182_11 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000619 205.0
TH1_k127_2533182_12 shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000002726 193.0
TH1_k127_2533182_13 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000071 147.0
TH1_k127_2533182_14 RDD family - - - 0.00000000000000000000000000001806 122.0
TH1_k127_2533182_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.514e-295 915.0
TH1_k127_2533182_3 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 587.0
TH1_k127_2533182_4 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 507.0
TH1_k127_2533182_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 452.0
TH1_k127_2533182_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 447.0
TH1_k127_2533182_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 385.0
TH1_k127_2533182_8 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 289.0
TH1_k127_2533182_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000001337 241.0
TH1_k127_2534653_0 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 336.0
TH1_k127_2534653_1 RecF/RecN/SMC N terminal domain K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002102 252.0
TH1_k127_2534653_2 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000007364 206.0
TH1_k127_2534653_3 Formylmethanofuran dehydrogenase, subunit e - - - 0.0000000000000000000000000000000000000000001815 171.0
TH1_k127_2534653_4 Cytochrome c7 and related cytochrome c - - - 0.00003383 49.0
TH1_k127_2542724_0 Polysulphide reductase, NrfD - - - 4.911e-201 632.0
TH1_k127_2542724_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 511.0
TH1_k127_2542724_2 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 429.0
TH1_k127_2542724_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 424.0
TH1_k127_2542724_4 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000005267 222.0
TH1_k127_2542724_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000001583 198.0
TH1_k127_2542724_6 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0003695 46.0
TH1_k127_2550588_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 9.132e-300 928.0
TH1_k127_2550588_1 PBP superfamily domain K03750,K07219 - 2.10.1.1 3.078e-249 784.0
TH1_k127_2550588_2 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 359.0
TH1_k127_2550588_3 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 333.0
TH1_k127_2550588_4 LysM domain K01449,K19223 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000003126 273.0
TH1_k127_2550588_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000006119 187.0
TH1_k127_2550588_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000004369 187.0
TH1_k127_2550588_7 Iron-containing alcohol dehydrogenase K13954 - 1.1.1.1 0.00000000000000000000000002376 108.0
TH1_k127_2550588_8 - - - - 0.00000000000000000000001057 111.0
TH1_k127_2550588_9 Mut7-C ubiquitin - - - 0.000000000000000005008 85.0
TH1_k127_2551056_0 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 504.0
TH1_k127_2551056_1 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 467.0
TH1_k127_2551056_2 Putative regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004472 229.0
TH1_k127_2551056_3 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000001344 201.0
TH1_k127_2551056_4 - - - - 0.00000000000000000000000000000000000000000000002617 172.0
TH1_k127_2551056_5 Muconolactone delta-isomerase K03464 - 5.3.3.4 0.00000000000000000000000000000000000000000009265 163.0
TH1_k127_2551056_6 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.0000000000000000000000000003556 114.0
TH1_k127_256031_0 Endoribonuclease that initiates mRNA decay K18682 - - 5.608e-218 687.0
TH1_k127_256031_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 430.0
TH1_k127_256031_2 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 364.0
TH1_k127_256031_3 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 349.0
TH1_k127_256031_4 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 316.0
TH1_k127_256031_5 pfam abc K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 289.0
TH1_k127_256031_6 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000179 274.0
TH1_k127_256031_7 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000005016 186.0
TH1_k127_256031_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000001138 179.0
TH1_k127_256708_0 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 410.0
TH1_k127_256708_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 348.0
TH1_k127_256708_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002961 278.0
TH1_k127_256708_3 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000005702 220.0
TH1_k127_256708_4 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000002234 165.0
TH1_k127_256708_5 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.00000000000000000000000000000000000000001836 159.0
TH1_k127_256708_6 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000001213 126.0
TH1_k127_256708_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000001858 67.0
TH1_k127_2626499_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 557.0
TH1_k127_2626499_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000002394 177.0
TH1_k127_2626499_2 Psort location Cytoplasmic, score 8.96 - - - 0.000000000002126 70.0
TH1_k127_2635491_0 GAF domain - - - 1.42e-239 772.0
TH1_k127_2635491_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 561.0
TH1_k127_2635491_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006738 269.0
TH1_k127_2635491_11 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000001495 244.0
TH1_k127_2635491_12 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000008048 231.0
TH1_k127_2635491_13 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000002512 224.0
TH1_k127_2635491_14 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000005111 234.0
TH1_k127_2635491_15 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000055 192.0
TH1_k127_2635491_16 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000002154 184.0
TH1_k127_2635491_18 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000003488 121.0
TH1_k127_2635491_19 protein with SCP PR1 domains - - - 0.000000000000000002706 93.0
TH1_k127_2635491_2 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 495.0
TH1_k127_2635491_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 496.0
TH1_k127_2635491_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 476.0
TH1_k127_2635491_5 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 374.0
TH1_k127_2635491_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 345.0
TH1_k127_2635491_7 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 337.0
TH1_k127_2635491_8 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 332.0
TH1_k127_2635491_9 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 314.0
TH1_k127_2652169_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 1.484e-279 893.0
TH1_k127_2652169_1 Pyridine nucleotide-disulphide oxidoreductase K15022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 403.0
TH1_k127_2652169_2 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 376.0
TH1_k127_2679205_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 599.0
TH1_k127_2679205_1 FAD binding domain K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000002312 210.0
TH1_k127_2687728_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 3.428e-216 694.0
TH1_k127_2687728_1 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 535.0
TH1_k127_2687728_2 - K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 437.0
TH1_k127_2687728_3 dUTP biosynthetic process K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000001086 250.0
TH1_k127_2687728_4 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000001046 214.0
TH1_k127_2687728_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000007468 211.0
TH1_k127_2687728_6 - - - - 0.00000000000000000000000000000000000000000000000000000009697 207.0
TH1_k127_2687728_7 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000000000000001444 101.0
TH1_k127_2687728_8 NhaP-type Na H and K H - - - 0.000000000000000003656 83.0
TH1_k127_2721066_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 4170.0
TH1_k127_2721066_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000007629 244.0
TH1_k127_2721066_2 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000002383 88.0
TH1_k127_2721066_3 Integrase core domain - - - 0.0002427 46.0
TH1_k127_2721066_4 bacterial OsmY and nodulation domain - - - 0.0008282 42.0
TH1_k127_275287_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 571.0
TH1_k127_275287_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000003111 205.0
TH1_k127_275287_2 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000001908 191.0
TH1_k127_275287_3 TPM domain K06872 - - 0.00000000000000000000000000000000000000007938 161.0
TH1_k127_275287_4 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000388 125.0
TH1_k127_2760431_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.265e-294 914.0
TH1_k127_2760431_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 4.305e-219 689.0
TH1_k127_2760431_10 Universal stress protein - - - 0.0000000000000000000000000000000000000008462 153.0
TH1_k127_2760431_11 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000001147 136.0
TH1_k127_2760431_12 helix_turn_helix gluconate operon transcriptional repressor K03710 - - 0.000000000000000000000000000000001038 139.0
TH1_k127_2760431_13 - - - - 0.0000000000000000000000000000001252 126.0
TH1_k127_2760431_14 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000009006 88.0
TH1_k127_2760431_15 mercury ion transmembrane transporter activity K07213 - - 0.000000000000000002303 86.0
TH1_k127_2760431_2 B3/4 domain K01890 - 6.1.1.20 3.733e-206 662.0
TH1_k127_2760431_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 544.0
TH1_k127_2760431_4 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 494.0
TH1_k127_2760431_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 465.0
TH1_k127_2760431_6 phosphorelay signal transduction system K02584,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 464.0
TH1_k127_2760431_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000004333 241.0
TH1_k127_2760431_8 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000001204 179.0
TH1_k127_2760431_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000008469 163.0
TH1_k127_2770305_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1616.0
TH1_k127_2770305_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 8.452e-221 691.0
TH1_k127_2770305_10 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.000000000000000000000000000000666 126.0
TH1_k127_2770305_11 response regulator - - - 0.000000000000000000000001083 109.0
TH1_k127_2770305_12 YtkA-like - - - 0.0000000007025 64.0
TH1_k127_2770305_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 417.0
TH1_k127_2770305_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 370.0
TH1_k127_2770305_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 301.0
TH1_k127_2770305_5 Transcriptional regulatory protein, C terminal K07664 - - 0.000000000000000000000000000000000000000000000000000000000000000000001257 244.0
TH1_k127_2770305_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000005238 231.0
TH1_k127_2770305_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000001216 225.0
TH1_k127_2770305_8 CTP:tRNA cytidylyltransferase activity K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000009088 217.0
TH1_k127_2770305_9 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000001608 184.0
TH1_k127_2821044_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 578.0
TH1_k127_2821044_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002064 264.0
TH1_k127_2821044_2 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000003212 212.0
TH1_k127_2821044_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.000000000000000000000000000000000000000000000001295 185.0
TH1_k127_2821044_4 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000002616 151.0
TH1_k127_2821044_5 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000001239 156.0
TH1_k127_2821044_6 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000000000007883 143.0
TH1_k127_2821044_7 SMART Cold shock protein K03704 - - 0.0000000000000000000000000001052 115.0
TH1_k127_2821044_8 - - - - 0.0000000000000000002793 90.0
TH1_k127_2821044_9 - - - - 0.000000000003121 71.0
TH1_k127_2830543_0 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 307.0
TH1_k127_2830543_1 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005378 271.0
TH1_k127_2830543_2 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003512 258.0
TH1_k127_2830543_3 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000001204 179.0
TH1_k127_2864858_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 534.0
TH1_k127_2864858_1 CobB/CobQ-like glutamine amidotransferase domain K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 503.0
TH1_k127_2864858_10 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000008042 264.0
TH1_k127_2864858_11 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001168 252.0
TH1_k127_2864858_12 YbbR-like protein - - - 0.00000000000000000000000000000000000000000000000000000007811 203.0
TH1_k127_2864858_13 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.000000000000000000000000000000000000000000000000000006431 204.0
TH1_k127_2864858_14 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000001473 177.0
TH1_k127_2864858_15 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000001577 176.0
TH1_k127_2864858_16 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000008262 167.0
TH1_k127_2864858_17 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000001449 153.0
TH1_k127_2864858_18 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000001328 106.0
TH1_k127_2864858_19 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000007749 97.0
TH1_k127_2864858_2 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 451.0
TH1_k127_2864858_20 Regulatory protein, FmdB family - - - 0.00000000000000000005144 93.0
TH1_k127_2864858_21 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000001704 95.0
TH1_k127_2864858_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 394.0
TH1_k127_2864858_4 Competence protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 380.0
TH1_k127_2864858_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 343.0
TH1_k127_2864858_6 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 318.0
TH1_k127_2864858_7 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 312.0
TH1_k127_2864858_8 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 302.0
TH1_k127_2864858_9 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 304.0
TH1_k127_2918550_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.937e-242 760.0
TH1_k127_2918550_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 6.333e-241 757.0
TH1_k127_2918550_10 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000001998 158.0
TH1_k127_2918550_11 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.000000000000000000000000000000002747 130.0
TH1_k127_2918550_13 - - - - 0.00000001708 61.0
TH1_k127_2918550_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 565.0
TH1_k127_2918550_3 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 520.0
TH1_k127_2918550_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 395.0
TH1_k127_2918550_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 367.0
TH1_k127_2918550_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 357.0
TH1_k127_2918550_7 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 327.0
TH1_k127_2918550_8 Cytidylyltransferase K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000003397 246.0
TH1_k127_2918550_9 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000001443 230.0
TH1_k127_3022730_0 Sulfatase - - - 1.532e-269 838.0
TH1_k127_3022730_1 Iron-sulfur cluster-binding domain K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 542.0
TH1_k127_3022730_2 - - - - 0.00000000000000000003314 98.0
TH1_k127_3022730_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000103 81.0
TH1_k127_3048054_0 Belongs to the sirtuin family. Class K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003071 264.0
TH1_k127_3048054_1 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000003941 194.0
TH1_k127_3048054_3 Copper resistance protein CopZ K07213 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0001569 48.0
TH1_k127_3054024_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1719.0
TH1_k127_3054024_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 373.0
TH1_k127_3054024_2 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000637 263.0
TH1_k127_3054024_3 - - - - 0.000000000000000000000000000000000000000000000000000000000003027 212.0
TH1_k127_3054024_4 nucleotide metabolic process - - - 0.000000000000000000000000000000002854 137.0
TH1_k127_3054024_5 CARDB domain-containing protein,subtilase family protease - - - 0.0000000000000000000158 96.0
TH1_k127_3079227_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 449.0
TH1_k127_3079227_1 glucose sorbosone K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 426.0
TH1_k127_3079227_2 Belongs to the ABC transporter superfamily K02031,K12371,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 349.0
TH1_k127_3079227_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 333.0
TH1_k127_3079227_4 PFAM ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000003848 216.0
TH1_k127_3079227_5 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000003516 208.0
TH1_k127_3079227_6 MarC family integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000006326 190.0
TH1_k127_3079227_8 Protein of unknown function (DUF2628) - - - 0.000000000000000000002607 100.0
TH1_k127_3079227_9 ATP-binding region, ATPase domain protein domain protein - - - 0.0000000001507 73.0
TH1_k127_3083785_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 502.0
TH1_k127_3083785_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000001973 134.0
TH1_k127_3083785_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000157 118.0
TH1_k127_3083785_3 Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000000000001269 82.0
TH1_k127_3109677_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1067.0
TH1_k127_3109677_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.987e-247 773.0
TH1_k127_3109677_10 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 456.0
TH1_k127_3109677_11 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 443.0
TH1_k127_3109677_12 Bacterial regulatory protein, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 428.0
TH1_k127_3109677_13 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 419.0
TH1_k127_3109677_14 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 339.0
TH1_k127_3109677_15 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 266.0
TH1_k127_3109677_16 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000004276 272.0
TH1_k127_3109677_17 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001624 258.0
TH1_k127_3109677_18 phosphorelay sensor kinase activity K07709,K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000001838 257.0
TH1_k127_3109677_19 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000001882 236.0
TH1_k127_3109677_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.014e-231 730.0
TH1_k127_3109677_20 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000186 231.0
TH1_k127_3109677_21 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000009005 227.0
TH1_k127_3109677_22 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000001209 222.0
TH1_k127_3109677_23 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000454 213.0
TH1_k127_3109677_24 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000004475 207.0
TH1_k127_3109677_25 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000006562 192.0
TH1_k127_3109677_26 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000004062 190.0
TH1_k127_3109677_27 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000003814 171.0
TH1_k127_3109677_28 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000001115 168.0
TH1_k127_3109677_29 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.0000000000000000000000000000000000000002047 154.0
TH1_k127_3109677_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 9.131e-218 687.0
TH1_k127_3109677_30 Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000003847 151.0
TH1_k127_3109677_31 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000001182 138.0
TH1_k127_3109677_32 SMART HNH nuclease K07451 - - 0.0000000000000000000000000000006441 129.0
TH1_k127_3109677_33 LysM domain - - - 0.000000000000000000000000000002387 132.0
TH1_k127_3109677_34 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000000000003926 120.0
TH1_k127_3109677_36 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000004567 118.0
TH1_k127_3109677_37 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000001572 118.0
TH1_k127_3109677_38 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000003233 116.0
TH1_k127_3109677_39 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000003857 111.0
TH1_k127_3109677_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 610.0
TH1_k127_3109677_41 electron transfer activity K05337,K17247 - - 0.0000000000000000000000048 103.0
TH1_k127_3109677_42 - - - - 0.000000000000000000004582 96.0
TH1_k127_3109677_5 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 574.0
TH1_k127_3109677_6 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 561.0
TH1_k127_3109677_7 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 540.0
TH1_k127_3109677_8 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 504.0
TH1_k127_3109677_9 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 496.0
TH1_k127_3249904_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 493.0
TH1_k127_3249904_1 TIGRFAM flagellar hook-associated protein FlgK K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007705 276.0
TH1_k127_3249904_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000001708 166.0
TH1_k127_3249904_3 FlhB HrpN YscU SpaS Family K04061 - - 0.000000000000000000000009178 102.0
TH1_k127_3249904_4 Belongs to the bacterial flagellin family K02397 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000145 103.0
TH1_k127_3249904_7 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000001229 53.0
TH1_k127_3339433_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 428.0
TH1_k127_3339433_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 408.0
TH1_k127_3339433_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 328.0
TH1_k127_3339433_3 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 310.0
TH1_k127_3339433_4 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000214 223.0
TH1_k127_3382671_0 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 384.0
TH1_k127_3382671_1 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 345.0
TH1_k127_3487_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.551e-313 976.0
TH1_k127_3487_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.09e-297 925.0
TH1_k127_3487_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 456.0
TH1_k127_3487_11 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 444.0
TH1_k127_3487_12 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 397.0
TH1_k127_3487_13 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 360.0
TH1_k127_3487_14 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 361.0
TH1_k127_3487_15 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 339.0
TH1_k127_3487_16 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 341.0
TH1_k127_3487_17 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 328.0
TH1_k127_3487_18 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 335.0
TH1_k127_3487_19 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 325.0
TH1_k127_3487_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.497e-261 826.0
TH1_k127_3487_20 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 310.0
TH1_k127_3487_21 Thymidylate synthase complementing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 304.0
TH1_k127_3487_22 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 287.0
TH1_k127_3487_23 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002606 277.0
TH1_k127_3487_24 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001514 267.0
TH1_k127_3487_25 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000816 181.0
TH1_k127_3487_26 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000006233 184.0
TH1_k127_3487_27 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000001347 149.0
TH1_k127_3487_28 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000003363 135.0
TH1_k127_3487_29 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000000000000000000000003914 144.0
TH1_k127_3487_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 5.921e-197 620.0
TH1_k127_3487_30 Thiamine-binding protein - - - 0.0000000000000000000000000000002052 125.0
TH1_k127_3487_31 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000005064 111.0
TH1_k127_3487_33 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000001501 89.0
TH1_k127_3487_34 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.00000000000000002466 84.0
TH1_k127_3487_36 Protein of unknown function (DUF721) - - - 0.00000005086 61.0
TH1_k127_3487_4 Bacterial regulatory protein, Fis family K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 610.0
TH1_k127_3487_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 579.0
TH1_k127_3487_6 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 570.0
TH1_k127_3487_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 556.0
TH1_k127_3487_8 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 488.0
TH1_k127_3487_9 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 467.0
TH1_k127_356940_0 Citrate synthase, C-terminal domain K01647,K01659 - 2.3.3.1,2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 403.0
TH1_k127_356940_1 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 311.0
TH1_k127_356940_2 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000002409 175.0
TH1_k127_356940_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000002664 118.0
TH1_k127_356940_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000001814 114.0
TH1_k127_356940_5 Zinc finger cdgsh-type domain protein - - - 0.0000000000000000000000005632 105.0
TH1_k127_356940_6 Belongs to the 4-oxalocrotonate tautomerase family K01821 - 5.3.2.6 0.00000003061 54.0
TH1_k127_36487_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.568e-319 988.0
TH1_k127_36487_1 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 501.0
TH1_k127_36487_2 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 335.0
TH1_k127_36487_3 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009561 279.0
TH1_k127_36487_4 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000001659 166.0
TH1_k127_36487_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000005044 58.0
TH1_k127_3652485_0 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 332.0
TH1_k127_3652485_1 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000006548 174.0
TH1_k127_3652485_2 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000001046 92.0
TH1_k127_3657651_0 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 431.0
TH1_k127_3657651_1 - - - - 0.00000000000000000000000000000000000000000000000005426 180.0
TH1_k127_3657651_2 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.000000000000000000000000000000000000000000000001371 179.0
TH1_k127_3657651_3 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000003723 147.0
TH1_k127_3682563_0 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 543.0
TH1_k127_3682563_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 531.0
TH1_k127_3682563_10 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000001107 116.0
TH1_k127_3682563_11 Tetratricopeptide repeat - - - 0.0000000009267 70.0
TH1_k127_3682563_12 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000006433 64.0
TH1_k127_3682563_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 522.0
TH1_k127_3682563_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 511.0
TH1_k127_3682563_4 phosphorelay sensor kinase activity K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 432.0
TH1_k127_3682563_5 metal-dependent enzyme K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 310.0
TH1_k127_3682563_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000001198 240.0
TH1_k127_3682563_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001981 214.0
TH1_k127_3682563_8 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000001118 180.0
TH1_k127_3682563_9 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000000000003215 140.0
TH1_k127_3684451_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 345.0
TH1_k127_3684451_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000004499 194.0
TH1_k127_3684451_2 Protein of unknown function (DUF3187) - - - 0.0000000000000000000001488 109.0
TH1_k127_3684451_3 HDOD domain - - - 0.0006968 44.0
TH1_k127_3707896_0 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 452.0
TH1_k127_3707896_1 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 373.0
TH1_k127_3725469_0 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007587 249.0
TH1_k127_3725469_1 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000005266 216.0
TH1_k127_3725469_2 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000000000001679 199.0
TH1_k127_3725469_3 homoserine transmembrane transporter activity K06600,K06895 - - 0.00000000000000000000000000000000000000000000000000002484 196.0
TH1_k127_3725469_4 Acetyltransferase - - - 0.00000000000000000000000000108 119.0
TH1_k127_3725469_5 Domain of unknown function (DUF3786) - - - 0.000000000000000001161 94.0
TH1_k127_3725469_6 part of a sulfur-relay system K11179 - - 0.000000000000000008648 84.0
TH1_k127_3725469_7 - - - - 0.0003676 45.0
TH1_k127_3741412_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.576e-208 653.0
TH1_k127_3741412_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 5.248e-204 639.0
TH1_k127_3741412_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 8.974e-198 622.0
TH1_k127_3741412_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 609.0
TH1_k127_3741412_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 451.0
TH1_k127_3741412_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 345.0
TH1_k127_3741412_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 340.0
TH1_k127_3741412_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001582 254.0
TH1_k127_3741412_8 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000025 171.0
TH1_k127_3746586_0 PFAM Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 494.0
TH1_k127_3746586_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 395.0
TH1_k127_3746586_10 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000003414 155.0
TH1_k127_3746586_11 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000002717 98.0
TH1_k127_3746586_2 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 314.0
TH1_k127_3746586_3 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 320.0
TH1_k127_3746586_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 306.0
TH1_k127_3746586_5 Belongs to the precorrin methyltransferase family K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001524 278.0
TH1_k127_3746586_6 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007168 259.0
TH1_k127_3746586_7 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001055 259.0
TH1_k127_3746586_8 TIGRFAM precorrin-2 C20-methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.00000000000000000000000000000000000000000000000000000000000001549 222.0
TH1_k127_3746586_9 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000002994 195.0
TH1_k127_3756200_0 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 485.0
TH1_k127_3756200_1 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 422.0
TH1_k127_3756200_2 FliG middle domain K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002 278.0
TH1_k127_3756200_3 Flagellar basal body rod FlgEFG protein C-terminal K02388 - - 0.000000000000000000000000000000000000104 147.0
TH1_k127_3756200_4 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000002261 89.0
TH1_k127_3756200_5 Flagellar assembly protein FliH K02411 - - 0.0000000000000007556 85.0
TH1_k127_3756200_6 PFAM MgtE intracellular K02383 - - 0.00000000000001055 81.0
TH1_k127_3756200_7 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000001543 62.0
TH1_k127_37614_0 DNA polymerase Ligase (LigD) - - - 1.273e-308 964.0
TH1_k127_37614_1 4Fe-4S binding domain - - - 4.946e-219 690.0
TH1_k127_37614_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000543 74.0
TH1_k127_37614_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 405.0
TH1_k127_37614_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 340.0
TH1_k127_37614_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 322.0
TH1_k127_37614_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001008 255.0
TH1_k127_37614_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000005934 224.0
TH1_k127_37614_7 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000000000000002416 176.0
TH1_k127_37614_8 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000003305 162.0
TH1_k127_37614_9 Male sterility protein K01897 - 6.2.1.3 0.00000000000000000000000000000000001689 145.0
TH1_k127_3792406_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 371.0
TH1_k127_3792406_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 371.0
TH1_k127_3792406_2 RecR protein K06187 - - 0.0000000000000000000000000000000000000000000000000000000000005455 214.0
TH1_k127_3792406_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000296 137.0
TH1_k127_3793050_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 4.715e-196 620.0
TH1_k127_3793050_1 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 400.0
TH1_k127_3820006_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 417.0
TH1_k127_3820006_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000000000005214 186.0
TH1_k127_3820006_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000006138 105.0
TH1_k127_3820006_3 GDP-mannose mannosyl hydrolase activity - - - 0.000000000000000000008563 94.0
TH1_k127_3839562_0 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 480.0
TH1_k127_3839562_1 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 401.0
TH1_k127_3839562_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 330.0
TH1_k127_3839562_3 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 329.0
TH1_k127_3839562_4 Site-specific recombinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009638 235.0
TH1_k127_3847887_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 429.0
TH1_k127_3847887_1 Formate dehydrogenase N, transmembrane K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 316.0
TH1_k127_3847887_2 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000006546 178.0
TH1_k127_3847887_3 Prokaryotic cytochrome b561 K00127 - - 0.00000000000000000000000000000000000001028 152.0
TH1_k127_3847887_4 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000002985 72.0
TH1_k127_3848416_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 567.0
TH1_k127_3848416_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 565.0
TH1_k127_3848416_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 430.0
TH1_k127_3848416_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 384.0
TH1_k127_3848416_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 336.0
TH1_k127_3848416_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 299.0
TH1_k127_3848416_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001193 282.0
TH1_k127_3851567_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.0 1195.0
TH1_k127_3851567_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 6.111e-304 939.0
TH1_k127_3851567_11 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000271 223.0
TH1_k127_3851567_12 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000001901 213.0
TH1_k127_3851567_13 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000002016 170.0
TH1_k127_3851567_14 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000001373 148.0
TH1_k127_3851567_15 AMP binding - - - 0.0000000000000000000000000000008916 126.0
TH1_k127_3851567_16 COGs COG4446 conserved - - - 0.0000000000000000000000000002499 118.0
TH1_k127_3851567_18 protein secretion K03116,K03117 - - 0.000000000000007521 79.0
TH1_k127_3851567_2 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 4.987e-289 905.0
TH1_k127_3851567_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 486.0
TH1_k127_3851567_4 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 436.0
TH1_k127_3851567_5 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 353.0
TH1_k127_3851567_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 332.0
TH1_k127_3851567_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 331.0
TH1_k127_3851567_8 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 293.0
TH1_k127_3851567_9 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004946 266.0
TH1_k127_3859266_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 354.0
TH1_k127_3859266_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 297.0
TH1_k127_3859266_2 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 299.0
TH1_k127_3859266_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000001377 245.0
TH1_k127_3859266_4 - - - - 0.00000000000000000000000000005537 119.0
TH1_k127_3866944_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 631.0
TH1_k127_3866944_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 509.0
TH1_k127_3866944_2 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 293.0
TH1_k127_3866944_3 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001774 262.0
TH1_k127_3866944_4 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000009654 232.0
TH1_k127_3866944_5 Universal stress protein family - - - 0.000000000000000000000000000000000000000000002455 169.0
TH1_k127_3866944_6 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000002909 160.0
TH1_k127_3866944_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000003987 153.0
TH1_k127_3869222_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 7.265e-285 882.0
TH1_k127_3869222_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 339.0
TH1_k127_3869222_10 PFAM Uncharacterised protein family UPF0150 - - - 0.00001983 49.0
TH1_k127_3869222_2 PFAM metal-dependent phosphohydrolase HD sub - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 329.0
TH1_k127_3869222_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 324.0
TH1_k127_3869222_4 Nitrite and sulphite reductase 4Fe-4S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 326.0
TH1_k127_3869222_5 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 299.0
TH1_k127_3869222_6 Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000765 258.0
TH1_k127_3869222_7 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000009856 98.0
TH1_k127_3869222_8 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000001256 75.0
TH1_k127_3869222_9 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000008041 66.0
TH1_k127_3881316_0 Acyl-protein synthetase, LuxE - - - 6.806e-255 792.0
TH1_k127_3881316_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 605.0
TH1_k127_3881551_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 2.834e-214 675.0
TH1_k127_3881551_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 487.0
TH1_k127_3881551_10 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000147 191.0
TH1_k127_3881551_11 HDOD domain - - - 0.000000000000000000000000000000000000000000000004271 182.0
TH1_k127_3881551_12 PFAM response regulator receiver K07657,K07659,K07664,K11329 - - 0.00000000000000000000000001078 111.0
TH1_k127_3881551_13 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000000002101 104.0
TH1_k127_3881551_14 Histidine kinase K01769,K11959 - 4.6.1.2 0.0000002278 61.0
TH1_k127_3881551_2 Dehydratase family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009619 462.0
TH1_k127_3881551_3 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 441.0
TH1_k127_3881551_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 412.0
TH1_k127_3881551_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 400.0
TH1_k127_3881551_6 response regulator receiver K02481,K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 381.0
TH1_k127_3881551_7 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 349.0
TH1_k127_3881551_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 340.0
TH1_k127_3881551_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001748 274.0
TH1_k127_3956865_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 571.0
TH1_k127_3956865_1 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000001161 205.0
TH1_k127_3956865_2 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000004441 128.0
TH1_k127_3956865_3 AMP binding - - - 0.00000000001217 76.0
TH1_k127_3956865_4 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000007529 52.0
TH1_k127_3978865_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 357.0
TH1_k127_3978865_1 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 311.0
TH1_k127_3978865_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000001928 239.0
TH1_k127_3978865_3 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000003383 137.0
TH1_k127_3978865_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000004335 126.0
TH1_k127_4009149_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003042 267.0
TH1_k127_4009149_1 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008781 242.0
TH1_k127_4009149_2 Belongs to the heat shock protein 70 family - - - 0.000000000000000000000000000006561 126.0
TH1_k127_4009149_3 - - - - 0.00000000000000000004988 96.0
TH1_k127_4009149_4 - - - - 0.000001171 52.0
TH1_k127_4040442_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 604.0
TH1_k127_4040442_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 579.0
TH1_k127_4040442_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 443.0
TH1_k127_4040442_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 361.0
TH1_k127_4040442_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 325.0
TH1_k127_4040442_5 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000000004442 122.0
TH1_k127_4055882_0 Conserved hypothetical protein 698 - - - 4.21e-239 747.0
TH1_k127_4055882_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000008536 234.0
TH1_k127_4055882_2 AMP binding - - - 0.000000000000000000000000452 109.0
TH1_k127_4062985_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 466.0
TH1_k127_4062985_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000017 278.0
TH1_k127_4062985_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000001539 244.0
TH1_k127_4062985_3 Universal stress protein - - - 0.000000000000000000000000000000000000000007694 157.0
TH1_k127_4062985_4 - - - - 0.00000000000000000000000001893 111.0
TH1_k127_4062985_5 HEAT repeat - - - 0.0000000000000000006305 95.0
TH1_k127_4069573_0 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000079 150.0
TH1_k127_4069573_1 pyridoxamine 5-phosphate oxidase-related K07005 - - 0.000000000000000000000000000000002944 133.0
TH1_k127_4069573_2 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000002198 85.0
TH1_k127_4069573_3 Universal stress protein - - - 0.000359 49.0
TH1_k127_4069573_4 Sigma-54 interaction domain - - - 0.0005777 48.0
TH1_k127_4132367_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 559.0
TH1_k127_4132367_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 447.0
TH1_k127_4132367_10 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000001244 119.0
TH1_k127_4132367_11 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.0000000003406 62.0
TH1_k127_4132367_2 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 338.0
TH1_k127_4132367_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 297.0
TH1_k127_4132367_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000001092 244.0
TH1_k127_4132367_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000002918 218.0
TH1_k127_4132367_6 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.00000000000000000000000000000000000000002258 159.0
TH1_k127_4132367_7 Protein of unknown function (DUF1284) K09706 - - 0.0000000000000000000000000000000000002352 144.0
TH1_k127_4132367_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000002865 142.0
TH1_k127_4132367_9 bacterial (prokaryotic) histone like domain K04764 - - 0.00000000000000000000000000003356 120.0
TH1_k127_420199_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.178e-263 832.0
TH1_k127_420199_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.754e-225 711.0
TH1_k127_420199_10 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001837 282.0
TH1_k127_420199_11 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002905 280.0
TH1_k127_420199_12 pyridoxamine 5-phosphate oxidase-related K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003641 241.0
TH1_k127_420199_13 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000001065 232.0
TH1_k127_420199_14 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000353 253.0
TH1_k127_420199_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003631 237.0
TH1_k127_420199_17 Short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000001017 166.0
TH1_k127_420199_18 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000004649 151.0
TH1_k127_420199_19 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000003104 114.0
TH1_k127_420199_2 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 546.0
TH1_k127_420199_20 HDOD domain - - - 0.000000000000000005593 88.0
TH1_k127_420199_22 protein homooligomerization - - - 0.0000000000006809 78.0
TH1_k127_420199_23 Histidine kinase - - - 0.000000000001261 72.0
TH1_k127_420199_24 deoxyhypusine monooxygenase activity - - - 0.00000000003644 75.0
TH1_k127_420199_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 498.0
TH1_k127_420199_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 462.0
TH1_k127_420199_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 468.0
TH1_k127_420199_6 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 437.0
TH1_k127_420199_7 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 377.0
TH1_k127_420199_8 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 302.0
TH1_k127_420199_9 PFAM Metal-dependent hydrolase HDOD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 298.0
TH1_k127_4247599_0 Chain length determinant protein K16554 - - 2.103e-204 659.0
TH1_k127_4247599_1 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 513.0
TH1_k127_4247599_2 PFAM ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 429.0
TH1_k127_4247599_3 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 364.0
TH1_k127_4247599_4 UDP-N-acetylmuramyl pentapeptide K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 309.0
TH1_k127_4247599_5 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004286 276.0
TH1_k127_4247599_6 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000001279 239.0
TH1_k127_4247599_7 Putative beta-barrel porin 2 K20920 - - 0.000000000000000000000000000000000000000000000000000003416 209.0
TH1_k127_4247599_8 PFAM SMP-30 Gluconolaconase K20952 - - 0.0000000000000000000000000000000000000001408 174.0
TH1_k127_4247599_9 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000002065 167.0
TH1_k127_4254610_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 547.0
TH1_k127_4254610_1 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000000000000004801 211.0
TH1_k127_4254610_2 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000008972 173.0
TH1_k127_4254610_3 Hydrogenase expression formation protein K04653 - - 0.000001032 53.0
TH1_k127_4270897_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 7.339e-214 673.0
TH1_k127_4270897_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 3.244e-195 619.0
TH1_k127_4270897_10 Proteasome subunit K01419 - 3.4.25.2 0.000000000000000000000001682 103.0
TH1_k127_4270897_11 - - - - 0.0000000000000000001845 94.0
TH1_k127_4270897_12 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000002653 83.0
TH1_k127_4270897_14 - - - - 0.0000009344 54.0
TH1_k127_4270897_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 503.0
TH1_k127_4270897_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 491.0
TH1_k127_4270897_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 384.0
TH1_k127_4270897_5 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 334.0
TH1_k127_4270897_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000007523 265.0
TH1_k127_4270897_7 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000005126 203.0
TH1_k127_4270897_8 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000007938 150.0
TH1_k127_4270897_9 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000005289 111.0
TH1_k127_4302579_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 567.0
TH1_k127_4302579_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 548.0
TH1_k127_4302579_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 319.0
TH1_k127_4302579_3 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000002967 139.0
TH1_k127_4302579_4 PFAM tRNA pseudouridine synthase D TruD K06176 - 5.4.99.27 0.0000000000000000000000000000209 121.0
TH1_k127_4302579_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000003768 118.0
TH1_k127_4302579_6 response regulator K10943 - - 0.0000000000000006749 81.0
TH1_k127_4313741_0 Bacterial transcriptional activator domain - - - 4.393e-213 700.0
TH1_k127_4313741_1 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 394.0
TH1_k127_4313741_10 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000009236 150.0
TH1_k127_4313741_2 TIGRFAM YD repeat protein K21449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 361.0
TH1_k127_4313741_3 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 323.0
TH1_k127_4313741_4 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 312.0
TH1_k127_4313741_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000002981 229.0
TH1_k127_4313741_6 2 iron, 2 sulfur cluster binding K01465,K02823,K05784,K17828 - 1.3.1.14,3.5.2.3 0.000000000000000000000000000000000000000000000000000000000009112 215.0
TH1_k127_4313741_7 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000005926 206.0
TH1_k127_4313741_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000000000000000002206 198.0
TH1_k127_4313741_9 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000002899 176.0
TH1_k127_4320545_0 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000000000000000002163 211.0
TH1_k127_4320545_1 Addiction module toxin, Txe YoeB - - - 0.0000000000000000000000000000000001718 133.0
TH1_k127_4320545_2 Antitoxin component of a toxin-antitoxin (TA) module K08591,K19159 - 2.3.1.15 0.000000000000000000000000000009214 119.0
TH1_k127_4320545_3 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000005199 109.0
TH1_k127_4421557_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1107.0
TH1_k127_4421557_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 4.849e-203 648.0
TH1_k127_4421557_2 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000008325 210.0
TH1_k127_4474422_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.282e-258 809.0
TH1_k127_4474422_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000003367 136.0
TH1_k127_4483947_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 421.0
TH1_k127_4483947_1 Transcriptional modulator of MazE toxin, MazF K07171,K18841 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000003042 162.0
TH1_k127_4483947_2 PFAM SpoVT AbrB K07172 - - 0.00000000000000000000000000000000000000006399 151.0
TH1_k127_4483947_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000001399 149.0
TH1_k127_4483947_4 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000001377 130.0
TH1_k127_4483947_6 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.000000001861 58.0
TH1_k127_4483947_7 CutA1 divalent ion tolerance protein K03926 - - 0.000000007917 63.0
TH1_k127_4574955_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2168.0
TH1_k127_4574955_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1991.0
TH1_k127_4574955_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000002292 137.0
TH1_k127_4574955_11 Domain of unknown function (DUF4136) - - - 0.0000000000000000000006176 103.0
TH1_k127_4574955_12 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000002403 82.0
TH1_k127_4574955_13 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000002508 82.0
TH1_k127_4574955_14 Evidence 5 No homology to any previously reported sequences - - - 0.000004785 48.0
TH1_k127_4574955_16 - - - - 0.0002279 49.0
TH1_k127_4574955_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.516e-231 718.0
TH1_k127_4574955_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 370.0
TH1_k127_4574955_4 TrkA-N domain K03455,K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 370.0
TH1_k127_4574955_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006812 272.0
TH1_k127_4574955_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005979 238.0
TH1_k127_4574955_7 Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008714 230.0
TH1_k127_4574955_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000002212 193.0
TH1_k127_4574955_9 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000001921 161.0
TH1_k127_4608688_0 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 306.0
TH1_k127_4608688_1 Protein of unknown function (DUF3108) - - - 0.000000000000000000000001309 117.0
TH1_k127_4608688_2 - - - - 0.00003051 52.0
TH1_k127_4873969_0 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 533.0
TH1_k127_4873969_1 Pfam:KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 417.0
TH1_k127_4873969_2 Protein of unknown function (DUF3574) - - - 0.00000000000000000000000000000000000000000000000000006315 189.0
TH1_k127_4873969_3 ORF6N domain - - - 0.000000000000008436 77.0
TH1_k127_4878779_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.992e-226 718.0
TH1_k127_4878779_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008656 263.0
TH1_k127_4878779_3 Protein of unknown function (DUF1573) - - - 0.0000008931 52.0
TH1_k127_4890551_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 417.0
TH1_k127_4890551_1 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 405.0
TH1_k127_4890551_2 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 394.0
TH1_k127_4890551_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000294 285.0
TH1_k127_4890551_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000003055 235.0
TH1_k127_4890551_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000005774 199.0
TH1_k127_4890551_6 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000001608 145.0
TH1_k127_4894320_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 6.019e-223 697.0
TH1_k127_4894320_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 403.0
TH1_k127_4894320_10 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 271.0
TH1_k127_4894320_11 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000005765 244.0
TH1_k127_4894320_12 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000001101 228.0
TH1_k127_4894320_13 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000003006 230.0
TH1_k127_4894320_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000003484 228.0
TH1_k127_4894320_15 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002778 201.0
TH1_k127_4894320_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000005886 194.0
TH1_k127_4894320_17 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001049 195.0
TH1_k127_4894320_18 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000004247 177.0
TH1_k127_4894320_19 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000003191 171.0
TH1_k127_4894320_2 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 406.0
TH1_k127_4894320_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000004317 172.0
TH1_k127_4894320_21 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000008271 174.0
TH1_k127_4894320_22 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000001436 157.0
TH1_k127_4894320_23 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000006604 155.0
TH1_k127_4894320_24 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000306 151.0
TH1_k127_4894320_25 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000001893 150.0
TH1_k127_4894320_26 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000001292 130.0
TH1_k127_4894320_27 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000003406 113.0
TH1_k127_4894320_28 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001038 108.0
TH1_k127_4894320_29 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000002727 113.0
TH1_k127_4894320_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 369.0
TH1_k127_4894320_30 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000003218 84.0
TH1_k127_4894320_31 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000006419 74.0
TH1_k127_4894320_32 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001722 70.0
TH1_k127_4894320_4 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 354.0
TH1_k127_4894320_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 342.0
TH1_k127_4894320_6 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 328.0
TH1_k127_4894320_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 300.0
TH1_k127_4894320_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 300.0
TH1_k127_4894320_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 293.0
TH1_k127_4909456_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 5.363e-201 637.0
TH1_k127_4909456_1 Telomere recombination K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 352.0
TH1_k127_4909456_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000004156 205.0
TH1_k127_4909456_11 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000000000000004751 186.0
TH1_k127_4909456_12 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000003533 181.0
TH1_k127_4909456_13 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000003745 160.0
TH1_k127_4909456_14 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000000000000000000001054 156.0
TH1_k127_4909456_15 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000001711 128.0
TH1_k127_4909456_16 cell redox homeostasis K02199 - - 0.0000000000000000000000000000001164 132.0
TH1_k127_4909456_17 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002388 112.0
TH1_k127_4909456_18 nickel cation binding K04651,K19640 - - 0.00000000000000000000000001814 114.0
TH1_k127_4909456_19 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000002959 115.0
TH1_k127_4909456_2 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 346.0
TH1_k127_4909456_21 receptor - - - 0.00001303 50.0
TH1_k127_4909456_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 325.0
TH1_k127_4909456_4 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 317.0
TH1_k127_4909456_5 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 308.0
TH1_k127_4909456_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 289.0
TH1_k127_4909456_7 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004463 269.0
TH1_k127_4909456_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000001185 218.0
TH1_k127_4909456_9 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000002411 207.0
TH1_k127_4931053_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 461.0
TH1_k127_4931053_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 419.0
TH1_k127_4931053_10 SMART Signal transduction response regulator, receiver domain - - - 0.000000000000000000000000000000000000000000000000000005134 201.0
TH1_k127_4931053_11 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000457 181.0
TH1_k127_4931053_12 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000002489 130.0
TH1_k127_4931053_13 Protein of unknown function (DUF3617) - - - 0.00000000000000000002319 97.0
TH1_k127_4931053_15 - - - - 0.00000000007262 69.0
TH1_k127_4931053_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 384.0
TH1_k127_4931053_3 response regulator K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 335.0
TH1_k127_4931053_4 membrane K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 320.0
TH1_k127_4931053_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002344 261.0
TH1_k127_4931053_6 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000001748 245.0
TH1_k127_4931053_7 PFAM Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000001594 224.0
TH1_k127_4931053_8 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000001055 219.0
TH1_k127_4931053_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000002958 194.0
TH1_k127_4954980_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 389.0
TH1_k127_4954980_1 Ferritin Dps family protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 297.0
TH1_k127_4954980_2 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000002633 213.0
TH1_k127_4954980_3 HDOD domain - - - 0.000000000000000000000000000000000000000000000000009356 190.0
TH1_k127_4954980_4 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.00000000000000000000000000000000001372 146.0
TH1_k127_4954980_5 - - - - 0.0000004346 54.0
TH1_k127_4978705_0 40-residue yvtn family beta-propeller repeat protein - - - 1.114e-204 657.0
TH1_k127_4978705_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 454.0
TH1_k127_4978705_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 457.0
TH1_k127_4978705_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 345.0
TH1_k127_4978705_4 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000225 246.0
TH1_k127_4978705_5 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172,K18357 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000003126 213.0
TH1_k127_4978705_6 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000003103 197.0
TH1_k127_4978705_7 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000005374 127.0
TH1_k127_4978705_8 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000001207 122.0
TH1_k127_5006031_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 5.158e-258 805.0
TH1_k127_5006031_1 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 443.0
TH1_k127_5006031_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 426.0
TH1_k127_5006031_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 362.0
TH1_k127_5006031_4 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 315.0
TH1_k127_5006031_5 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000004562 221.0
TH1_k127_5006031_6 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000005143 194.0
TH1_k127_5006031_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.00000000000000000000000000000001502 134.0
TH1_k127_5006031_9 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000001142 80.0
TH1_k127_5047288_0 molybdopterin cofactor binding K08352 - 1.8.5.5 1.413e-258 814.0
TH1_k127_5047288_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 289.0
TH1_k127_5047288_2 membrane transporter protein K07090 - - 0.00000000000000003181 81.0
TH1_k127_5072628_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.542e-241 752.0
TH1_k127_5072628_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 5.311e-232 727.0
TH1_k127_5072628_10 SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000006897 215.0
TH1_k127_5072628_11 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000008102 216.0
TH1_k127_5072628_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000001817 153.0
TH1_k127_5072628_13 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000006938 64.0
TH1_k127_5072628_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.435e-224 713.0
TH1_k127_5072628_3 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 534.0
TH1_k127_5072628_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 516.0
TH1_k127_5072628_5 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 408.0
TH1_k127_5072628_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 356.0
TH1_k127_5072628_7 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 327.0
TH1_k127_5072628_8 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000006081 244.0
TH1_k127_5072628_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000005415 227.0
TH1_k127_5094746_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 7.924e-269 852.0
TH1_k127_5094746_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 510.0
TH1_k127_5094746_2 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 444.0
TH1_k127_5094746_3 - - - - 0.0000000000000000000000000000000000000000000003766 170.0
TH1_k127_5094746_4 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000006611 178.0
TH1_k127_5094746_5 IMP dehydrogenase activity - - - 0.0000000000000000000000000000000000000000001046 167.0
TH1_k127_5094746_6 response regulator - - - 0.00000000000000000000000000000000000008069 147.0
TH1_k127_5094746_7 Histidine kinase - - - 0.000000000000000000000003853 111.0
TH1_k127_5094746_8 phosphorelay signal transduction system - - - 0.0000000000000000000002056 104.0
TH1_k127_5094746_9 phosphorelay signal transduction system - - - 0.00000000005041 63.0
TH1_k127_5106186_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 362.0
TH1_k127_5106186_1 Domain of unknown function (DUF4380) - - - 0.0001232 53.0
TH1_k127_5126173_0 DNA polymerase K02347 - - 6.092e-215 677.0
TH1_k127_5126173_1 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 617.0
TH1_k127_5126173_10 Cadherin repeats. - - - 0.00000000000000000000002987 116.0
TH1_k127_5126173_11 signal peptide processing K03100,K12062,K13280 - 3.4.21.89 0.00000000000000000008035 95.0
TH1_k127_5126173_12 alginic acid biosynthetic process - - - 0.000000000000000008946 98.0
TH1_k127_5126173_14 - - - - 0.0000000007431 61.0
TH1_k127_5126173_15 Belongs to the ompA family - - - 0.0001051 55.0
TH1_k127_5126173_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 458.0
TH1_k127_5126173_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 347.0
TH1_k127_5126173_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 314.0
TH1_k127_5126173_5 protein secretion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 317.0
TH1_k127_5126173_6 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003171 291.0
TH1_k127_5126173_7 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002129 255.0
TH1_k127_5126173_8 - - - - 0.00000000000000000000000000000000000000000000000000664 196.0
TH1_k127_5126173_9 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.000000000000000000000000000000000005787 149.0
TH1_k127_5135777_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 2.955e-213 673.0
TH1_k127_5135777_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 408.0
TH1_k127_5135777_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000005054 189.0
TH1_k127_5194250_0 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.0 1258.0
TH1_k127_5194250_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 325.0
TH1_k127_5194250_10 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000001995 111.0
TH1_k127_5194250_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003127 280.0
TH1_k127_5194250_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002828 274.0
TH1_k127_5194250_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000001275 246.0
TH1_k127_5194250_5 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000002683 179.0
TH1_k127_5194250_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000002477 171.0
TH1_k127_5194250_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000023 142.0
TH1_k127_5194250_8 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000799 125.0
TH1_k127_5194250_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000008496 119.0
TH1_k127_5198727_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 555.0
TH1_k127_5198727_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 473.0
TH1_k127_5198727_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 458.0
TH1_k127_5198727_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 419.0
TH1_k127_5198727_4 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 385.0
TH1_k127_5198727_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 374.0
TH1_k127_5198727_6 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 355.0
TH1_k127_5198727_7 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000863 216.0
TH1_k127_5198727_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000000000000000205 174.0
TH1_k127_5208046_0 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0 1130.0
TH1_k127_5208046_1 cell redox homeostasis - - - 3.246e-222 698.0
TH1_k127_5208046_10 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 325.0
TH1_k127_5208046_11 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 309.0
TH1_k127_5208046_12 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 291.0
TH1_k127_5208046_13 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 289.0
TH1_k127_5208046_14 Mg2 transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001731 287.0
TH1_k127_5208046_15 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004804 267.0
TH1_k127_5208046_16 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000001294 216.0
TH1_k127_5208046_17 DNA integration K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000007817 220.0
TH1_k127_5208046_18 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000003228 197.0
TH1_k127_5208046_19 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000000000001461 196.0
TH1_k127_5208046_2 Aminotransferase class-III K01845 - 5.4.3.8 3.49e-209 658.0
TH1_k127_5208046_20 UPF0056 membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000002924 188.0
TH1_k127_5208046_21 Belongs to the Fur family K02076,K03711 GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000007211 184.0
TH1_k127_5208046_22 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000006823 175.0
TH1_k127_5208046_23 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000008376 168.0
TH1_k127_5208046_24 PFAM thioesterase superfamily K02614 - - 0.000000000000000000000000000000000000000001402 162.0
TH1_k127_5208046_25 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000001571 138.0
TH1_k127_5208046_26 YGGT family K02221 - - 0.0000000000000000000000000000001377 128.0
TH1_k127_5208046_27 - - - - 0.00000000000000000000002616 107.0
TH1_k127_5208046_3 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 605.0
TH1_k127_5208046_4 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 564.0
TH1_k127_5208046_5 DHHA2 domain K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009693 549.0
TH1_k127_5208046_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 501.0
TH1_k127_5208046_7 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 468.0
TH1_k127_5208046_8 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 388.0
TH1_k127_5208046_9 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 342.0
TH1_k127_5227831_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 441.0
TH1_k127_5227831_1 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 382.0
TH1_k127_5227831_10 sulfur relay protein TusB DsrH K07237 - - 0.000001984 53.0
TH1_k127_5227831_11 DsrE/DsrF-like family K07235 - - 0.000004807 51.0
TH1_k127_5227831_12 Tetratricopeptide repeat protein - - - 0.0002902 51.0
TH1_k127_5227831_2 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008296 389.0
TH1_k127_5227831_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 297.0
TH1_k127_5227831_4 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002665 255.0
TH1_k127_5227831_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000425 203.0
TH1_k127_5227831_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000002785 198.0
TH1_k127_5227831_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000008854 185.0
TH1_k127_5227831_8 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000001588 153.0
TH1_k127_5227831_9 DsrE/DsrF-like family K07236 - - 0.0000001309 57.0
TH1_k127_5231054_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 314.0
TH1_k127_5231054_1 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000000000000000000000000000001944 157.0
TH1_k127_5231054_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000006556 135.0
TH1_k127_5231054_3 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000001134 135.0
TH1_k127_5274202_0 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001306 281.0
TH1_k127_5274202_1 - - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000005454 169.0
TH1_k127_5274202_2 Cysteine-rich domain - - - 0.00000000000000000000007063 100.0
TH1_k127_5274202_3 - - - - 0.0000000000000000000001418 102.0
TH1_k127_5300671_0 Nitroreductase - - - 1.868e-202 645.0
TH1_k127_5300671_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 1.484e-196 629.0
TH1_k127_5300671_2 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 298.0
TH1_k127_5300671_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008755 278.0
TH1_k127_5300671_4 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001114 278.0
TH1_k127_5300671_5 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003276 267.0
TH1_k127_5300671_6 tRNA modification K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000003577 174.0
TH1_k127_5300671_7 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000001528 169.0
TH1_k127_5354743_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 498.0
TH1_k127_5354743_1 Domain of unknown function (DUF4881) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009372 268.0
TH1_k127_5354743_2 - - - - 0.00000000000000000000000000000000000000000000005997 179.0
TH1_k127_5354743_3 membrane transporter protein K07090 - - 0.000000000000000000000004702 102.0
TH1_k127_5394440_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 1.149e-243 766.0
TH1_k127_5394440_1 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 496.0
TH1_k127_5398232_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 4.092e-300 926.0
TH1_k127_5398232_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K05588 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 440.0
TH1_k127_5398232_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 383.0
TH1_k127_5398232_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 308.0
TH1_k127_5398232_4 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000004659 268.0
TH1_k127_5398232_5 PFAM NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002097 260.0
TH1_k127_5398232_6 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K05586 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000001428 209.0
TH1_k127_5398232_7 PFAM nickel-dependent hydrogenase, large subunit K00436 - 1.12.1.2 0.0000000000000000000000000000000000003387 143.0
TH1_k127_5407754_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1209.0
TH1_k127_5407754_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 370.0
TH1_k127_5407754_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 334.0
TH1_k127_5407754_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000002282 209.0
TH1_k127_5407754_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000001783 79.0
TH1_k127_5424870_0 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 484.0
TH1_k127_5424870_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 421.0
TH1_k127_5424870_2 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 417.0
TH1_k127_5424870_3 Signal transduction histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 363.0
TH1_k127_5424870_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 335.0
TH1_k127_5424870_5 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000002566 151.0
TH1_k127_5436339_0 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 377.0
TH1_k127_5436339_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000006211 238.0
TH1_k127_5436339_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000006335 66.0
TH1_k127_5436339_3 Protein of unknown function (DUF3047) - - - 0.0000001086 55.0
TH1_k127_5445314_0 arsenite transmembrane transporter activity - - - 5.821e-252 795.0
TH1_k127_5445314_1 metal ion transport K14445 - - 3.137e-245 765.0
TH1_k127_5445314_10 Universal stress protein - - - 0.000228 52.0
TH1_k127_5445314_2 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 409.0
TH1_k127_5445314_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002534 247.0
TH1_k127_5445314_4 domain protein K03499,K05571 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655 - 0.00000000000000000000000000000000000000000000000000000000148 205.0
TH1_k127_5445314_5 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000002932 215.0
TH1_k127_5445314_6 IMP dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000001424 186.0
TH1_k127_5445314_7 response regulator K02667 - - 0.000000000000000000000001354 108.0
TH1_k127_5445314_8 Universal stress protein - - - 0.0000001308 59.0
TH1_k127_5445314_9 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00009517 52.0
TH1_k127_5448547_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 2.622e-275 856.0
TH1_k127_5448547_1 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009406 273.0
TH1_k127_5448547_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0000000000000000000000000000000000000000000000000000001707 199.0
TH1_k127_5448547_3 PIN domain - - - 0.00005236 53.0
TH1_k127_5498020_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.238e-195 626.0
TH1_k127_5498020_1 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 385.0
TH1_k127_5498020_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 343.0
TH1_k127_5498020_3 membrane K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 342.0
TH1_k127_5498020_4 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 290.0
TH1_k127_5498020_5 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008748 275.0
TH1_k127_5498020_6 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000000000006316 195.0
TH1_k127_5498020_7 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000001718 133.0
TH1_k127_5498020_8 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000134 44.0
TH1_k127_5590065_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 314.0
TH1_k127_5590065_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008992 298.0
TH1_k127_5590065_2 Dimerisation domain of Zinc Transporter - - - 0.0005295 51.0
TH1_k127_5617685_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 5.203e-260 807.0
TH1_k127_5617685_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 426.0
TH1_k127_5617685_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 319.0
TH1_k127_571676_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1797.0
TH1_k127_571676_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.945e-303 937.0
TH1_k127_571676_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.566e-204 643.0
TH1_k127_571676_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 417.0
TH1_k127_571676_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 370.0
TH1_k127_571676_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 370.0
TH1_k127_571676_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003181 254.0
TH1_k127_571676_7 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000001664 241.0
TH1_k127_571676_8 - - - - 0.0000000000000000000000000000000000000000000000000000008362 199.0
TH1_k127_571676_9 Rubrerythrin - - - 0.00000000000000002037 86.0
TH1_k127_5778080_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 9.944e-267 857.0
TH1_k127_5778080_1 Highly conserved protein containing a thioredoxin domain K06888 - - 3.649e-246 775.0
TH1_k127_5778080_10 RmlD substrate binding domain K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005498 273.0
TH1_k127_5778080_11 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000003029 211.0
TH1_k127_5778080_12 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000003604 194.0
TH1_k127_5778080_13 cyclic nucleotide binding K01420,K10716,K10914,K16922 - - 0.000000000000000000000000000000000000000000006421 173.0
TH1_k127_5778080_14 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000005871 126.0
TH1_k127_5778080_15 Tetratricopeptide repeat - - - 0.00000000000000000000003888 108.0
TH1_k127_5778080_17 - - - - 0.00003024 47.0
TH1_k127_5778080_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 511.0
TH1_k127_5778080_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 431.0
TH1_k127_5778080_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 403.0
TH1_k127_5778080_5 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 379.0
TH1_k127_5778080_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 388.0
TH1_k127_5778080_7 sugar transferase K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 367.0
TH1_k127_5778080_8 PFAM Glycosyl transferase family 2 K12992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 317.0
TH1_k127_5778080_9 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009474 269.0
TH1_k127_58360_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 346.0
TH1_k127_58360_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 329.0
TH1_k127_58360_2 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006047 271.0
TH1_k127_58360_3 Winged helix-turn helix K18996 - - 0.00000000000000000000000000000000000000000000000006558 185.0
TH1_k127_58360_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000006491 180.0
TH1_k127_5854464_0 4Fe-4S dicluster domain - - - 1.887e-299 924.0
TH1_k127_5854464_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 509.0
TH1_k127_5854464_2 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 452.0
TH1_k127_5854464_3 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000642 199.0
TH1_k127_5854464_4 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000000000002511 162.0
TH1_k127_5854464_5 lyase activity - - - 0.0000000000000000000000000000000000001329 149.0
TH1_k127_5854464_6 - - - - 0.000000000000000000007122 94.0
TH1_k127_5854464_7 deoxyhypusine monooxygenase activity K05385 - - 0.00000000000000000002043 94.0
TH1_k127_5898315_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1517.0
TH1_k127_5898315_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.869e-265 832.0
TH1_k127_5898315_10 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000002742 232.0
TH1_k127_5898315_11 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000006848 203.0
TH1_k127_5898315_12 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000005818 125.0
TH1_k127_5898315_13 Regulatory protein, FmdB family - - - 0.000000000003094 68.0
TH1_k127_5898315_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 603.0
TH1_k127_5898315_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 318.0
TH1_k127_5898315_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 301.0
TH1_k127_5898315_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 298.0
TH1_k127_5898315_6 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004821 267.0
TH1_k127_5898315_7 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000005348 263.0
TH1_k127_5898315_8 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000001619 240.0
TH1_k127_5898315_9 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000001403 238.0
TH1_k127_6089427_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 6.608e-275 861.0
TH1_k127_6089427_1 AMP binding - - - 0.0000000000000000000000000000000000002136 145.0
TH1_k127_6107522_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 582.0
TH1_k127_6107522_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 542.0
TH1_k127_6107522_2 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 467.0
TH1_k127_6107522_3 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 332.0
TH1_k127_6107522_4 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
TH1_k127_6107522_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000002724 240.0
TH1_k127_6107522_6 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000000000000756 173.0
TH1_k127_6107522_7 PIN domain - - - 0.00000000000000000008822 94.0
TH1_k127_6122195_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 9.393e-248 779.0
TH1_k127_6122195_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 3.886e-196 621.0
TH1_k127_6122195_10 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000006188 242.0
TH1_k127_6122195_11 nitric oxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000006989 212.0
TH1_k127_6122195_12 EthD domain - - - 0.0000000000000000000000000000000000000000000000000004332 185.0
TH1_k127_6122195_13 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000000000000000009226 163.0
TH1_k127_6122195_14 COGs COG4446 conserved - - - 0.00000000000000000000000000000000000005643 148.0
TH1_k127_6122195_15 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000001013 145.0
TH1_k127_6122195_16 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.00000000000000000000003951 105.0
TH1_k127_6122195_17 Uncharacterized ACR, COG1678 - - - 0.000000000000001621 81.0
TH1_k127_6122195_18 - - - - 0.000000000000004133 82.0
TH1_k127_6122195_19 - - - - 0.00000000000002999 77.0
TH1_k127_6122195_2 Domain of unknown function (DUF1957) K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 604.0
TH1_k127_6122195_20 Domain of unknown function (DUF4912) K09942 - - 0.00000000002747 75.0
TH1_k127_6122195_21 electron transfer activity K05337,K17247 - - 0.00000009578 55.0
TH1_k127_6122195_22 - - - - 0.0000001708 56.0
TH1_k127_6122195_3 Alpha amylase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 559.0
TH1_k127_6122195_4 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 541.0
TH1_k127_6122195_5 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 494.0
TH1_k127_6122195_6 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 466.0
TH1_k127_6122195_7 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 383.0
TH1_k127_6122195_8 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 328.0
TH1_k127_6122195_9 PFAM Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 312.0
TH1_k127_6133147_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009202 336.0
TH1_k127_6133147_1 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002571 279.0
TH1_k127_6133147_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003519 260.0
TH1_k127_6133147_3 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000006536 211.0
TH1_k127_6133147_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000002994 59.0
TH1_k127_6133147_6 Decaheme c-type cytochrome, DmsE family - - - 0.00000002828 60.0
TH1_k127_613440_0 Type II/IV secretion system protein K02454,K02652 - - 4.965e-204 651.0
TH1_k127_613440_1 Signal transducing histidine kinase homodimeric K03407,K13490 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 518.0
TH1_k127_613440_10 Pilus assembly protein, PilP K02665 - - 0.0000000000003614 77.0
TH1_k127_613440_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 463.0
TH1_k127_613440_3 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 408.0
TH1_k127_613440_4 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 319.0
TH1_k127_613440_5 chemotaxis K03408 - - 0.00000000000000000000000000000000000000403 150.0
TH1_k127_613440_6 cheY-homologous receiver domain K02658 - - 0.00000000000000000000000000000000000001725 147.0
TH1_k127_613440_7 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000003074 146.0
TH1_k127_613440_8 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000003198 125.0
TH1_k127_613440_9 phosphorelay signal transduction system - - - 0.00000000000000000000000002323 123.0
TH1_k127_6177337_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 1.145e-286 905.0
TH1_k127_6177337_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 546.0
TH1_k127_6177337_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000003797 230.0
TH1_k127_6177337_11 ( 3 oxidation state) methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000001576 159.0
TH1_k127_6177337_12 Transcriptional - - - 0.000000000000000000000000000000000172 135.0
TH1_k127_6177337_13 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000006916 143.0
TH1_k127_6177337_14 protein domain associated with - - - 0.00000000000000000000000000005846 121.0
TH1_k127_6177337_16 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000002641 108.0
TH1_k127_6177337_17 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000001494 75.0
TH1_k127_6177337_18 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000211 77.0
TH1_k127_6177337_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644 503.0
TH1_k127_6177337_20 - - - - 0.00000000005887 65.0
TH1_k127_6177337_3 cysteine-tRNA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 458.0
TH1_k127_6177337_4 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 450.0
TH1_k127_6177337_5 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 386.0
TH1_k127_6177337_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 373.0
TH1_k127_6177337_7 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 293.0
TH1_k127_6177337_8 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000002109 260.0
TH1_k127_6177337_9 Glycosyl transferase group 1 K00696,K13058 GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,2.4.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000004171 265.0
TH1_k127_6206265_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 312.0
TH1_k127_6206265_1 Memo-like protein K06990 - - 0.00000000000000000000000000000000000009125 145.0
TH1_k127_6206265_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000006456 133.0
TH1_k127_6206265_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000003474 92.0
TH1_k127_6244403_0 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 531.0
TH1_k127_6244403_1 Di-haem cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 489.0
TH1_k127_6244403_2 Cysteine synthase A K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 375.0
TH1_k127_6244403_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 361.0
TH1_k127_6244403_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 357.0
TH1_k127_6244403_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 292.0
TH1_k127_6244403_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002061 251.0
TH1_k127_6244403_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000000000002412 173.0
TH1_k127_6244403_8 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000002762 173.0
TH1_k127_6255034_0 Sigma-54 interaction domain - - - 1.841e-199 629.0
TH1_k127_6255034_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 349.0
TH1_k127_6265605_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 3.685e-258 812.0
TH1_k127_6265605_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 554.0
TH1_k127_6265605_2 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000002097 179.0
TH1_k127_6265605_3 - - - - 0.000000000000002187 78.0
TH1_k127_6265605_4 Protein of unknown function (DUF2868) - - - 0.0000000000005067 82.0
TH1_k127_6265605_5 Hsp70 protein - - - 0.00000003428 66.0
TH1_k127_6265605_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000007376 56.0
TH1_k127_6265605_7 PFAM transposase IS116 IS110 IS902 family - - - 0.00004872 46.0
TH1_k127_6328376_0 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 518.0
TH1_k127_6328376_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 477.0
TH1_k127_6328376_10 Histidine kinase - - - 0.000002205 50.0
TH1_k127_6328376_2 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 342.0
TH1_k127_6328376_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 352.0
TH1_k127_6328376_4 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003929 282.0
TH1_k127_6328376_5 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009465 265.0
TH1_k127_6328376_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000001063 250.0
TH1_k127_6328376_7 - - - - 0.0000000000000000000000000000000000000000000002256 182.0
TH1_k127_6328376_8 MarR family transcriptional K15973 - - 0.000000000000000000000000000000000000000000002482 168.0
TH1_k127_6328376_9 Sirohaem synthase dimerisation region K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000073 162.0
TH1_k127_6385372_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1285.0
TH1_k127_6385372_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1184.0
TH1_k127_6385372_10 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000001351 180.0
TH1_k127_6385372_11 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.0000000000000000000000000000000000000000000000004353 179.0
TH1_k127_6385372_12 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000003878 140.0
TH1_k127_6385372_13 SpoVT / AbrB like domain - - - 0.0000001914 53.0
TH1_k127_6385372_14 Winged helix-turn helix K18996 - - 0.0003365 45.0
TH1_k127_6385372_2 Phosphoglycerate kinase K00927 - 2.7.2.3 9.414e-199 626.0
TH1_k127_6385372_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 570.0
TH1_k127_6385372_4 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 496.0
TH1_k127_6385372_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 411.0
TH1_k127_6385372_6 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 395.0
TH1_k127_6385372_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 368.0
TH1_k127_6385372_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 310.0
TH1_k127_6385372_9 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 287.0
TH1_k127_6400160_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 492.0
TH1_k127_6400160_1 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 438.0
TH1_k127_6400160_10 Sporulation related domain - - - 0.00003653 54.0
TH1_k127_6400160_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 330.0
TH1_k127_6400160_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 288.0
TH1_k127_6400160_4 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001292 273.0
TH1_k127_6400160_5 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000000000000000000000000000000000000000000000000001631 208.0
TH1_k127_6400160_6 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000007749 195.0
TH1_k127_6400160_7 Uncharacterized protein family UPF0054 K07042 - - 0.00000000000000000000001243 107.0
TH1_k127_6400160_8 Protein of unknown function (DUF2905) - - - 0.00000000000000000001116 96.0
TH1_k127_6400160_9 Tetratricopeptide repeat - - - 0.00000000000000000001553 100.0
TH1_k127_6401270_0 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 553.0
TH1_k127_6401270_1 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 539.0
TH1_k127_6401270_2 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000000004236 180.0
TH1_k127_6401270_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000002063 158.0
TH1_k127_6401270_4 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000003736 154.0
TH1_k127_6401270_5 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000004629 117.0
TH1_k127_6433100_0 Peptidase family M28 - - - 0.0 1105.0
TH1_k127_6433100_1 Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000006835 186.0
TH1_k127_6433100_2 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.000000000000000000000000000000000000000006588 160.0
TH1_k127_6483702_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 353.0
TH1_k127_6483702_1 proteolysis K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001722 247.0
TH1_k127_6483702_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000002352 218.0
TH1_k127_6483702_3 Belongs to the peptidase S11 family K01286,K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000009535 196.0
TH1_k127_6483702_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000001158 163.0
TH1_k127_6483702_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000007065 143.0
TH1_k127_6483702_6 Stringent starvation protein B K09985 - - 0.000000000000000000000000001354 119.0
TH1_k127_6483702_7 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 0.00000000000000000000001913 110.0
TH1_k127_6486918_0 Ftsk_gamma K03466 - - 1.97e-209 678.0
TH1_k127_6486918_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 7.574e-197 627.0
TH1_k127_6486918_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 552.0
TH1_k127_6486918_3 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 501.0
TH1_k127_6486918_4 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 370.0
TH1_k127_6486918_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000002346 267.0
TH1_k127_6486918_6 NOG31153 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000212 241.0
TH1_k127_6486918_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000003129 199.0
TH1_k127_6486918_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000003407 79.0
TH1_k127_6527069_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1004.0
TH1_k127_6527069_1 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.0000000000000002476 81.0
TH1_k127_6527069_2 Nucleotidyltransferase domain - - - 0.00000006541 59.0
TH1_k127_6531597_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.799e-272 847.0
TH1_k127_6531597_1 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 507.0
TH1_k127_6531597_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 438.0
TH1_k127_6531597_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 344.0
TH1_k127_6531597_4 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 315.0
TH1_k127_6531597_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 308.0
TH1_k127_6531597_6 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000000000000000000000009262 221.0
TH1_k127_6531597_7 Bacterial regulatory proteins, crp family - - - 0.000000000000000000000000000000000000000000000000002272 192.0
TH1_k127_6531597_8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000005707 97.0
TH1_k127_6531597_9 PilZ domain - - - 0.0000000001142 68.0
TH1_k127_6548715_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1750.0
TH1_k127_6548715_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.349e-222 695.0
TH1_k127_6548715_2 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 614.0
TH1_k127_6548715_3 PFAM Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 597.0
TH1_k127_6548715_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 554.0
TH1_k127_6548715_5 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 414.0
TH1_k127_6548715_6 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 357.0
TH1_k127_6548715_7 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000003084 173.0
TH1_k127_6548715_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000321 145.0
TH1_k127_6548715_9 - - - - 0.0000000000000000000000000003532 124.0
TH1_k127_6563447_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 4.186e-210 671.0
TH1_k127_6624578_0 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 503.0
TH1_k127_6624578_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 407.0
TH1_k127_6624578_2 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000008305 227.0
TH1_k127_6624578_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000008687 143.0
TH1_k127_6624578_4 cell redox homeostasis - - - 0.000000000000000000000003924 104.0
TH1_k127_6624578_5 Thioredoxin K03671 - - 0.000000000000000000000324 103.0
TH1_k127_6624578_7 Domain of unknown function (DUF2703) - - - 0.000000001215 65.0
TH1_k127_6665373_0 Domain of unknown function (DUF4384) - - - 0.00000000005878 73.0
TH1_k127_6665373_1 - - - - 0.0008715 51.0
TH1_k127_6670606_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 394.0
TH1_k127_6670606_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 287.0
TH1_k127_6670606_2 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000339 275.0
TH1_k127_6670606_3 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000006077 248.0
TH1_k127_7090812_0 General secretory system II, protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 527.0
TH1_k127_7090812_1 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 462.0
TH1_k127_7090812_10 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000008966 222.0
TH1_k127_7090812_11 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000002163 190.0
TH1_k127_7090812_12 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000004464 168.0
TH1_k127_7090812_13 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000195 165.0
TH1_k127_7090812_14 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.00000000000000000000000000000000000000003053 166.0
TH1_k127_7090812_2 Domain of unknown function (DUF3413) K07014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 392.0
TH1_k127_7090812_3 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 364.0
TH1_k127_7090812_4 PFAM glycosyl transferase, family 9 K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 315.0
TH1_k127_7090812_5 biosynthesis glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 302.0
TH1_k127_7090812_6 Mo-molybdopterin cofactor metabolic process K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002391 248.0
TH1_k127_7090812_7 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000003022 235.0
TH1_k127_7090812_8 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000001346 238.0
TH1_k127_7090812_9 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000006328 221.0
TH1_k127_7298625_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0 1072.0
TH1_k127_7298625_1 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 398.0
TH1_k127_7298625_2 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 389.0
TH1_k127_7298625_3 2Fe-2S -binding domain K13483 - - 0.000000000000000000000000000000000000000000000000000000000000000004746 238.0
TH1_k127_7298625_4 LysM domain K16291 - - 0.0000000000000000000000000000001725 128.0
TH1_k127_7298625_5 - - - - 0.000000000001993 68.0
TH1_k127_7298625_6 - - - - 0.00003569 48.0
TH1_k127_7304660_0 TIGRFAM type IV-A pilus assembly ATPase PilB K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 549.0
TH1_k127_7304660_1 Cobalamin synthesis G N-terminal K13541 - 2.1.1.131,3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 477.0
TH1_k127_7304660_10 - - - - 0.000447 42.0
TH1_k127_7304660_2 Biotin-protein ligase, N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 302.0
TH1_k127_7304660_3 HEPN domain - - - 0.0000000000000000000000000009205 117.0
TH1_k127_7304660_4 4Fe-4S binding domain - - - 0.000000000000000007832 84.0
TH1_k127_7304660_5 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000001611 61.0
TH1_k127_7304660_6 PGAP1-like protein - - - 0.0000006627 60.0
TH1_k127_7304660_7 Nucleotidyltransferase domain - - - 0.000000989 55.0
TH1_k127_7304660_8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000001086 54.0
TH1_k127_7304660_9 Belongs to the DsrF TusC family K07236 - - 0.0001412 49.0
TH1_k127_7316137_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001039 263.0
TH1_k127_7316137_1 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000002935 162.0
TH1_k127_7316137_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000001369 123.0
TH1_k127_7316137_3 - - - - 0.0000000000000000000000000001717 118.0
TH1_k127_7320034_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1043.0
TH1_k127_7320034_1 Bacterial transcriptional activator domain - - - 1.832e-209 690.0
TH1_k127_7320034_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 537.0
TH1_k127_7320034_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 364.0
TH1_k127_7320034_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000009724 239.0
TH1_k127_7320034_5 NhaP-type Na H and K H - - - 0.000000000000000000000000000000000007394 138.0
TH1_k127_7320034_6 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.0000000000000001585 80.0
TH1_k127_7320034_7 Ribbon-helix-helix protein, copG family - - - 0.0000000000000005404 82.0
TH1_k127_7321126_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 6.564e-229 719.0
TH1_k127_7321126_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 534.0
TH1_k127_7321126_10 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000000004057 148.0
TH1_k127_7321126_11 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000000000008983 128.0
TH1_k127_7321126_2 Ecdysteroid kinase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 462.0
TH1_k127_7321126_3 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 427.0
TH1_k127_7321126_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 378.0
TH1_k127_7321126_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 350.0
TH1_k127_7321126_6 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 346.0
TH1_k127_7321126_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 319.0
TH1_k127_7321126_8 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001426 257.0
TH1_k127_7321126_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000002116 249.0
TH1_k127_7351538_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 9.497e-257 804.0
TH1_k127_7351538_1 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 482.0
TH1_k127_7351538_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 371.0
TH1_k127_7351538_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 367.0
TH1_k127_7351538_4 - - - - 0.000000000000000000000000000000000000000000000000000000003927 205.0
TH1_k127_7351538_5 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000157 161.0
TH1_k127_7382037_0 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 437.0
TH1_k127_7382037_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 360.0
TH1_k127_7382037_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000008805 176.0
TH1_k127_7398768_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 4.942e-241 752.0
TH1_k127_7398768_1 Telomere recombination K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 501.0
TH1_k127_7398768_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282,K18008 - 1.12.2.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 469.0
TH1_k127_7398768_3 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000000000000001868 212.0
TH1_k127_7398768_4 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000004278 169.0
TH1_k127_7398768_5 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0000000000000000000000000006703 113.0
TH1_k127_7401088_0 Surface antigen K07277 - - 8.841e-276 867.0
TH1_k127_7401088_1 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 548.0
TH1_k127_7401088_10 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002448 269.0
TH1_k127_7401088_11 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000003334 241.0
TH1_k127_7401088_12 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000001637 226.0
TH1_k127_7401088_13 Psort location Cytoplasmic, score 8.96 K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000009093 238.0
TH1_k127_7401088_14 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000007369 198.0
TH1_k127_7401088_15 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000003601 180.0
TH1_k127_7401088_16 Outer membrane lipoprotein Slp family K07285 - - 0.0000000000000000000000000000000000000000000002853 172.0
TH1_k127_7401088_17 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000001411 169.0
TH1_k127_7401088_18 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.000000000000000000000000000000000000000001644 164.0
TH1_k127_7401088_19 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0000000000000000000000000000000000004194 153.0
TH1_k127_7401088_2 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 541.0
TH1_k127_7401088_20 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.0000000000000000000000000000000001351 141.0
TH1_k127_7401088_21 Type II secretion system protein B K02451 - - 0.00000000000000000000000001125 121.0
TH1_k127_7401088_22 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000265 93.0
TH1_k127_7401088_23 - - - - 0.00000000009722 66.0
TH1_k127_7401088_24 restriction endonuclease K07448 - - 0.00005644 45.0
TH1_k127_7401088_3 purine nucleobase transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 527.0
TH1_k127_7401088_4 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 526.0
TH1_k127_7401088_5 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 520.0
TH1_k127_7401088_6 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 426.0
TH1_k127_7401088_7 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 404.0
TH1_k127_7401088_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 374.0
TH1_k127_7401088_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 357.0
TH1_k127_7411248_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 496.0
TH1_k127_7411248_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 479.0
TH1_k127_7411248_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001267 273.0
TH1_k127_7411248_3 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000003387 194.0
TH1_k127_7411248_4 - - - - 0.00000000000000000000000000000000000000005125 154.0
TH1_k127_7435235_0 CARDB domain-containing protein,subtilase family protease - - - 6.27e-228 755.0
TH1_k127_7435235_1 DNA photolyase K01669 - 4.1.99.3 6.944e-197 622.0
TH1_k127_7435235_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 515.0
TH1_k127_7435235_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 384.0
TH1_k127_7435235_4 Redoxin K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000445 258.0
TH1_k127_7443515_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 582.0
TH1_k127_7443515_1 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 394.0
TH1_k127_7443515_2 electron transfer activity K00428 - 1.11.1.5 0.0000000004651 63.0
TH1_k127_7443515_3 Protein of unknown function (DUF3313) - - - 0.000458 48.0
TH1_k127_7502247_0 ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 552.0
TH1_k127_7502247_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 376.0
TH1_k127_7502247_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 310.0
TH1_k127_7502247_3 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
TH1_k127_7502247_4 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000004873 162.0
TH1_k127_7502247_5 Putative regulatory protein - - - 0.000000000000000000000005605 104.0
TH1_k127_7502941_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000004014 177.0
TH1_k127_7502941_1 - - - - 0.000000002558 68.0
TH1_k127_7563720_0 PFAM Type II secretion system protein E K02454 - - 3.943e-195 623.0
TH1_k127_7563720_1 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000005071 213.0
TH1_k127_7563720_2 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000009084 204.0
TH1_k127_7563720_3 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000000000000000005047 118.0
TH1_k127_7563720_4 PFAM General secretion pathway protein K K02460 - - 0.000000000000000000000000005922 122.0
TH1_k127_7563720_5 general secretion pathway protein K02456,K02457,K02458,K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000001601 61.0
TH1_k127_7563720_7 General secretion pathway protein H K02457 - - 0.000000188 61.0
TH1_k127_7563720_8 Type IV pilus assembly protein PilM; K02461 - - 0.00001035 58.0
TH1_k127_7563720_9 Subtilase family K08651 - 3.4.21.66 0.0009344 46.0
TH1_k127_7593323_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1520.0
TH1_k127_7593323_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 481.0
TH1_k127_7593323_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 332.0
TH1_k127_7593323_3 CO dehydrogenase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 314.0
TH1_k127_7593323_4 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 289.0
TH1_k127_7593323_5 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000002213 243.0
TH1_k127_7593323_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000000000000000000003611 158.0
TH1_k127_7593323_7 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000001276 134.0
TH1_k127_7593323_8 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000005744 96.0
TH1_k127_7593323_9 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000002719 67.0
TH1_k127_7663391_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1668.0
TH1_k127_7663391_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 489.0
TH1_k127_7663391_2 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 486.0
TH1_k127_7663391_3 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001289 268.0
TH1_k127_7663391_4 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000001219 189.0
TH1_k127_7665048_0 Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA K03498,K03499 GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 604.0
TH1_k127_7665048_1 domain protein K03499,K05571 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 450.0
TH1_k127_7665265_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1150.0
TH1_k127_7665265_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 6.032e-317 975.0
TH1_k127_7665265_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 395.0
TH1_k127_7665265_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 370.0
TH1_k127_7665265_4 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000007868 245.0
TH1_k127_7665265_5 - - - - 0.00000000000000000002712 92.0
TH1_k127_7704148_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 5.214e-223 711.0
TH1_k127_7704148_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 377.0
TH1_k127_7704148_10 sigma factor activity K02405,K03093 - - 0.000000000000000000000000000000000000000000000000007597 193.0
TH1_k127_7704148_11 Flagellar biosynthesis K02404 - - 0.000000000000000000000000000000000000000000001236 179.0
TH1_k127_7704148_12 PFAM flagellar basal body rod protein K02392 - - 0.000000000000000000000000000000000000001195 156.0
TH1_k127_7704148_13 PFAM surface presentation of antigens (SPOA) protein K02417 - - 0.0000000000000000000000000000000000003546 143.0
TH1_k127_7704148_14 ankyrin repeats K06867 - - 0.0000000000000000000000000000000001166 149.0
TH1_k127_7704148_15 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000253 134.0
TH1_k127_7704148_16 Role in flagellar biosynthesis K02421 - - 0.000000000000000000000000000000655 132.0
TH1_k127_7704148_17 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000001885 97.0
TH1_k127_7704148_18 Role in flagellar biosynthesis K02420 - - 0.0000000000000000003013 91.0
TH1_k127_7704148_19 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000001146 64.0
TH1_k127_7704148_2 flagellar basal-body rod protein FlgG K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 358.0
TH1_k127_7704148_20 PFAM Flagellar hook-length control protein K02414 - - 0.000009517 58.0
TH1_k127_7704148_3 Flagellar basal body protein FlaE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 356.0
TH1_k127_7704148_4 Cellulose biosynthesis protein BcsQ K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 289.0
TH1_k127_7704148_5 FliP family K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000461 256.0
TH1_k127_7704148_6 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001584 256.0
TH1_k127_7704148_7 flagellar motor switch protein FliM K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000375 253.0
TH1_k127_7704148_8 Signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000000665 229.0
TH1_k127_7704148_9 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000002312 218.0
TH1_k127_7749340_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 578.0
TH1_k127_7749340_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 424.0
TH1_k127_7749340_10 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000001785 125.0
TH1_k127_7749340_11 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000000002045 110.0
TH1_k127_7749340_12 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000005596 66.0
TH1_k127_7749340_2 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 354.0
TH1_k127_7749340_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 331.0
TH1_k127_7749340_4 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 291.0
TH1_k127_7749340_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000007078 249.0
TH1_k127_7749340_6 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000002839 243.0
TH1_k127_7749340_7 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008953 246.0
TH1_k127_7749340_8 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000001975 229.0
TH1_k127_7749340_9 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000006929 185.0
TH1_k127_7750222_0 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 500.0
TH1_k127_7750222_1 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000002822 227.0
TH1_k127_7750222_2 - - - - 0.0000000000000003117 81.0
TH1_k127_7804154_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1062.0
TH1_k127_7804154_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 2.218e-288 911.0
TH1_k127_7804154_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.218e-203 646.0
TH1_k127_7804154_3 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 547.0
TH1_k127_7804154_4 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 501.0
TH1_k127_7804154_5 belongs to the CobB CobQ family K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 363.0
TH1_k127_7804154_6 Cold shock K03704 - - 0.000000000000000000000001159 106.0
TH1_k127_7804154_7 Bacterial regulatory proteins, crp family K01420 - - 0.000000195 59.0
TH1_k127_786998_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.324e-233 746.0
TH1_k127_786998_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 614.0
TH1_k127_786998_2 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 483.0
TH1_k127_786998_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 467.0
TH1_k127_786998_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 449.0
TH1_k127_786998_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 436.0
TH1_k127_786998_6 gas vesicle protein - - - 0.00000000000000000000288 97.0
TH1_k127_786998_7 thiamine diphosphate biosynthetic process K03154 - - 0.000000000002088 70.0
TH1_k127_786998_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000003652 55.0
TH1_k127_7870226_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1032.0
TH1_k127_7870226_1 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 422.0
TH1_k127_7870226_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 388.0
TH1_k127_7870226_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588,K01945 - 5.4.99.18,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000002644 239.0
TH1_k127_7870226_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000003819 225.0
TH1_k127_7870226_5 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000003216 157.0
TH1_k127_7870226_6 histidine kinase A domain protein - - - 0.00000000000000006376 88.0
TH1_k127_7870226_7 Thioredoxin K03672 - 1.8.1.8 0.0000000002832 64.0
TH1_k127_7870226_8 Thioredoxin-like domain K03671 - - 0.0000003022 54.0
TH1_k127_79154_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 495.0
TH1_k127_79154_1 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006055 259.0
TH1_k127_79154_2 TIGRFAM flagellar motor stator protein MotA K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003057 244.0
TH1_k127_7973534_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 367.0
TH1_k127_7973534_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000005641 214.0
TH1_k127_7973534_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000001546 210.0
TH1_k127_7973534_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000009297 146.0
TH1_k127_7973534_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000004232 64.0
TH1_k127_7973534_5 - - - - 0.000007562 48.0
TH1_k127_8055827_0 Glycosyl transferase family 21 - - - 4.877e-197 627.0
TH1_k127_8055827_1 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 316.0
TH1_k127_8055827_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000002255 231.0
TH1_k127_8055827_4 COG0457 FOG TPR repeat - - - 0.0002285 53.0
TH1_k127_8094976_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 364.0
TH1_k127_8094976_1 DJ-1/PfpI family K03152,K05520,K05687 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000003542 252.0
TH1_k127_8094976_2 Bacterial regulatory proteins, crp family - - - 0.0000000000000000000000000000000000000001089 160.0
TH1_k127_8094976_3 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000001172 157.0
TH1_k127_8094976_5 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000001406 142.0
TH1_k127_8094976_6 Domain of Unknown Function (DUF748) - - - 0.00000000007786 71.0
TH1_k127_8132203_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 574.0
TH1_k127_8132203_1 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 451.0
TH1_k127_8132203_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 312.0
TH1_k127_8132203_3 amidohydrolase - - - 0.00000000000000000000000000000000000000000000001491 184.0
TH1_k127_8132203_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000006862 79.0
TH1_k127_8132203_5 - - - - 0.000000000000004752 85.0
TH1_k127_8132203_6 Polysaccharide deacetylase K01452,K14659,K22278 - 3.5.1.104,3.5.1.41 0.000000000002902 79.0
TH1_k127_8132203_7 Tetratricopeptide TPR_2 repeat protein - - - 0.00000004289 63.0
TH1_k127_8136830_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.281e-287 890.0
TH1_k127_8136830_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 598.0
TH1_k127_8136830_2 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 376.0
TH1_k127_8136830_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 340.0
TH1_k127_8136830_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 311.0
TH1_k127_8136830_5 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000002905 181.0
TH1_k127_8136830_6 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000003308 135.0
TH1_k127_8136830_7 - - - - 0.000000000000000373 80.0
TH1_k127_8136830_8 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000006093 78.0
TH1_k127_8136830_9 Sporulation and spore germination - - - 0.0000004227 59.0
TH1_k127_8175560_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 556.0
TH1_k127_8175560_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 456.0
TH1_k127_8175560_2 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 442.0
TH1_k127_8175560_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007819 283.0
TH1_k127_8175560_4 - - - - 0.00000000000000000000000000000000000000000001158 166.0
TH1_k127_8175560_5 Cold shock K03704 - - 0.00000000000000000000000001852 109.0
TH1_k127_8175560_6 phosphorelay signal transduction system - - - 0.00000000000000000000004835 104.0
TH1_k127_8175560_7 Histidine kinase - - - 0.00000000000000000005929 98.0
TH1_k127_8190616_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.271e-211 664.0
TH1_k127_8190616_1 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 498.0
TH1_k127_8223623_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 466.0
TH1_k127_8223623_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000002269 264.0
TH1_k127_8223623_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000003619 203.0
TH1_k127_8235368_0 Belongs to the heat shock protein 70 family - - - 6.409e-247 793.0
TH1_k127_8235368_1 Heat shock protein 70 family - - - 1.05e-205 656.0
TH1_k127_8235368_2 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 538.0
TH1_k127_8235368_3 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 389.0
TH1_k127_8235368_4 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 323.0
TH1_k127_8235368_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000007811 211.0
TH1_k127_8235368_6 Domain of unknown function (DUF2760) - - - 0.00000000000000000000000000000000000394 146.0
TH1_k127_83636_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 2.636e-232 727.0
TH1_k127_83636_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 495.0
TH1_k127_83636_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.00000000000000000000000000000000000000000000000000000000351 207.0
TH1_k127_83636_3 Rubrerythrin - - - 0.000000000001305 70.0
TH1_k127_8458330_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1e-322 1011.0
TH1_k127_8458330_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.927e-312 970.0
TH1_k127_8458330_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 3.071e-251 788.0
TH1_k127_8458330_3 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 490.0
TH1_k127_8458330_4 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 322.0
TH1_k127_8458330_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000002709 234.0
TH1_k127_8458330_6 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000003046 165.0
TH1_k127_8458330_7 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000002592 146.0
TH1_k127_8458330_8 - - - - 0.00000000001233 70.0
TH1_k127_8531351_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.286e-268 831.0
TH1_k127_8531351_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.679e-241 751.0
TH1_k127_8531351_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000285 282.0
TH1_k127_8531351_11 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004702 270.0
TH1_k127_8531351_12 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000007009 249.0
TH1_k127_8531351_13 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000002265 236.0
TH1_k127_8531351_14 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000003604 220.0
TH1_k127_8531351_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000002904 215.0
TH1_k127_8531351_16 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000000237 194.0
TH1_k127_8531351_17 OstA-like protein K09774 - - 0.00000000000000000000000000000000000000000000000001813 184.0
TH1_k127_8531351_18 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000001927 186.0
TH1_k127_8531351_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000003017 175.0
TH1_k127_8531351_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 504.0
TH1_k127_8531351_20 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000000000000004422 143.0
TH1_k127_8531351_21 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000001118 133.0
TH1_k127_8531351_22 Protein of unknown function (DUF2283) - - - 0.000000000000000000000000000002083 121.0
TH1_k127_8531351_24 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000002194 72.0
TH1_k127_8531351_25 Protein conserved in bacteria K11719 - - 0.00008576 51.0
TH1_k127_8531351_26 HDOD domain - - - 0.0005061 44.0
TH1_k127_8531351_3 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 433.0
TH1_k127_8531351_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 377.0
TH1_k127_8531351_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 360.0
TH1_k127_8531351_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 354.0
TH1_k127_8531351_7 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 319.0
TH1_k127_8531351_8 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 294.0
TH1_k127_8531351_9 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 299.0
TH1_k127_8542374_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 4.881e-197 622.0
TH1_k127_8542374_1 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 2.483e-196 619.0
TH1_k127_8582760_0 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 3.694e-202 651.0
TH1_k127_8582760_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 527.0
TH1_k127_8582760_2 ATPase (AAA superfamily K07133 - - 0.0000000000005879 80.0
TH1_k127_8582760_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000003559 58.0
TH1_k127_8589898_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1244.0
TH1_k127_8589898_1 CARDB domain-containing protein,subtilase family protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 587.0
TH1_k127_8589898_10 PFAM flavin reductase domain protein, FMN-binding - - - 0.0001326 51.0
TH1_k127_8589898_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 428.0
TH1_k127_8589898_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 289.0
TH1_k127_8589898_4 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000254 265.0
TH1_k127_8589898_5 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000002289 192.0
TH1_k127_8589898_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000123 152.0
TH1_k127_8589898_8 Sulfurtransferase TusA - - - 0.000000000000000000000006379 103.0
TH1_k127_8589898_9 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000001408 101.0
TH1_k127_8608801_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 2.819e-283 890.0
TH1_k127_8608801_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 536.0
TH1_k127_8608801_10 8-amino-7-oxononanoate synthase K00652,K01906 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.47,6.2.1.14 0.0000000006915 65.0
TH1_k127_8608801_2 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 443.0
TH1_k127_8608801_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000007441 255.0
TH1_k127_8608801_4 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000007623 213.0
TH1_k127_8608801_5 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000006281 198.0
TH1_k127_8608801_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000002069 119.0
TH1_k127_8608801_7 sensor histidine kinase - - - 0.000000000000000000000008363 117.0
TH1_k127_8608801_8 - - - - 0.0000000000001144 77.0
TH1_k127_8637876_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1570.0
TH1_k127_8637876_1 PFAM phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 537.0
TH1_k127_8637876_2 - K09004 - - 0.000000004353 59.0
TH1_k127_8647831_0 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 557.0
TH1_k127_8647831_1 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 437.0
TH1_k127_8647831_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 423.0
TH1_k127_8647831_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 296.0
TH1_k127_8647831_4 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000002104 205.0
TH1_k127_8647831_5 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.000000000000000000000000000000000000000000000006615 178.0
TH1_k127_8647831_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000001919 177.0
TH1_k127_8647831_7 protein complex oligomerization - - - 0.0000000000000000000000000000008066 128.0
TH1_k127_8647831_8 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000000084 114.0
TH1_k127_8647831_9 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000002002 70.0
TH1_k127_8667070_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.293e-261 816.0
TH1_k127_8667070_1 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 379.0
TH1_k127_8667070_2 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000034 177.0
TH1_k127_8667070_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000002606 112.0
TH1_k127_8667070_4 HYR domain - - - 0.00000000000001128 89.0
TH1_k127_8667070_5 exo-alpha-(2->6)-sialidase activity - - - 0.000000001178 73.0
TH1_k127_8667070_6 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000003196 68.0
TH1_k127_8716590_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.296e-227 714.0
TH1_k127_8716590_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 608.0
TH1_k127_8716590_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 459.0
TH1_k127_8716590_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 352.0
TH1_k127_8716590_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000005911 228.0
TH1_k127_8716590_5 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000003257 169.0
TH1_k127_8716590_6 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.00000000000000000000000000000004954 134.0
TH1_k127_8735701_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 475.0
TH1_k127_8735701_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 439.0
TH1_k127_8735701_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000003487 59.0
TH1_k127_8742429_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 4.643e-282 878.0
TH1_k127_8742429_1 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 468.0
TH1_k127_8742429_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 442.0
TH1_k127_8742429_3 PFAM CBS domain containing protein K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 309.0
TH1_k127_8748035_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1247.0
TH1_k127_8748035_1 Phosphofructokinase K00850 - 2.7.1.11 2.539e-208 655.0
TH1_k127_8748035_2 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 570.0
TH1_k127_8748035_3 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 490.0
TH1_k127_8748035_4 Cache_2 - - - 0.00000000000000000000000000000000000000000003765 168.0
TH1_k127_8748035_5 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.00000000000000000000000000000000000002678 151.0
TH1_k127_877160_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 7.376e-254 789.0
TH1_k127_877160_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 445.0
TH1_k127_877160_2 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 342.0
TH1_k127_877160_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 342.0
TH1_k127_877160_4 Biogenesis protein K09792 - - 0.000000000000000000000000000000000000000001046 166.0
TH1_k127_877160_5 FixH - - - 0.000000000000002607 86.0
TH1_k127_877160_6 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.000000000000005674 78.0
TH1_k127_877160_7 Cbb3-type cytochrome oxidase component FixQ - - - 0.000002772 51.0
TH1_k127_877160_8 FixH - - - 0.000014 56.0
TH1_k127_8852694_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1823.0
TH1_k127_8852694_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 1.65e-321 1000.0
TH1_k127_8852694_10 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 410.0
TH1_k127_8852694_11 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 405.0
TH1_k127_8852694_12 CbbQ/NirQ/NorQ C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 398.0
TH1_k127_8852694_13 Belongs to the SfsA family K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 393.0
TH1_k127_8852694_14 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 371.0
TH1_k127_8852694_15 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 321.0
TH1_k127_8852694_16 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 299.0
TH1_k127_8852694_17 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 286.0
TH1_k127_8852694_18 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002702 264.0
TH1_k127_8852694_19 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000764 259.0
TH1_k127_8852694_2 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.849e-312 967.0
TH1_k127_8852694_20 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000009291 257.0
TH1_k127_8852694_21 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003823 265.0
TH1_k127_8852694_22 4Fe-4S dicluster domain K00196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007237 248.0
TH1_k127_8852694_23 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004727 251.0
TH1_k127_8852694_24 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000528 247.0
TH1_k127_8852694_25 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000002967 236.0
TH1_k127_8852694_26 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000004038 226.0
TH1_k127_8852694_27 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000001895 223.0
TH1_k127_8852694_28 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000002806 192.0
TH1_k127_8852694_29 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000000000000007917 186.0
TH1_k127_8852694_3 GTP-binding protein TypA K06207 - - 2.561e-265 831.0
TH1_k127_8852694_30 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000000000002039 173.0
TH1_k127_8852694_31 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000004819 156.0
TH1_k127_8852694_32 metal cluster binding - - - 0.00000000000000000000000000000000000001071 149.0
TH1_k127_8852694_33 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000004194 144.0
TH1_k127_8852694_34 Smr domain - - - 0.0000000000000000000000000000001704 125.0
TH1_k127_8852694_35 membrane - - - 0.0000000000000000000000000002131 121.0
TH1_k127_8852694_36 PFAM MscS Mechanosensitive ion channel K03442 - - 0.00000000000000000002211 96.0
TH1_k127_8852694_37 energy transducer activity K03646,K03832 - - 0.0000000000000000002382 89.0
TH1_k127_8852694_39 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00001516 49.0
TH1_k127_8852694_4 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 606.0
TH1_k127_8852694_5 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 511.0
TH1_k127_8852694_6 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009386 499.0
TH1_k127_8852694_7 Von Willebrand factor type A K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 466.0
TH1_k127_8852694_8 PFAM Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 447.0
TH1_k127_8852694_9 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 446.0
TH1_k127_8897874_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 566.0
TH1_k127_8897874_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 576.0
TH1_k127_8897874_10 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0001025 46.0
TH1_k127_8897874_11 - - - - 0.0002559 46.0
TH1_k127_8897874_2 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 494.0
TH1_k127_8897874_3 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 474.0
TH1_k127_8897874_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 318.0
TH1_k127_8897874_5 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 296.0
TH1_k127_8897874_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000002446 226.0
TH1_k127_8897874_7 - - - - 0.000000000000000000000000000000001348 141.0
TH1_k127_8897874_8 - - - - 0.0000000000000000000000000000003321 133.0
TH1_k127_8897874_9 - - - - 0.000000002053 58.0
TH1_k127_8932312_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1135.0
TH1_k127_8932312_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 7.156e-216 672.0
TH1_k127_8932312_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000004312 243.0
TH1_k127_8932312_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000007502 218.0
TH1_k127_8932312_4 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000004498 53.0
TH1_k127_9006849_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 9.144e-239 745.0
TH1_k127_9006849_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 1.142e-216 683.0
TH1_k127_9006849_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 336.0
TH1_k127_9006849_11 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 308.0
TH1_k127_9006849_12 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 294.0
TH1_k127_9006849_13 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000209 281.0
TH1_k127_9006849_14 PFAM Sulphate transporter K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004809 288.0
TH1_k127_9006849_15 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001822 293.0
TH1_k127_9006849_16 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000003407 242.0
TH1_k127_9006849_17 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000005505 230.0
TH1_k127_9006849_18 phosphatidate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000009259 221.0
TH1_k127_9006849_19 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000586 212.0
TH1_k127_9006849_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 2.337e-206 650.0
TH1_k127_9006849_20 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000001256 198.0
TH1_k127_9006849_21 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000001546 189.0
TH1_k127_9006849_22 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000007058 190.0
TH1_k127_9006849_23 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000006109 182.0
TH1_k127_9006849_24 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000001069 174.0
TH1_k127_9006849_25 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000264 173.0
TH1_k127_9006849_26 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000000000000000000002339 159.0
TH1_k127_9006849_27 methyltransferase - - - 0.00000000000000000000000000000000000000018 157.0
TH1_k127_9006849_28 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000009171 145.0
TH1_k127_9006849_29 RNA-binding protein containing a PIN domain K06962 - - 0.0000000000000000000000000000000002119 138.0
TH1_k127_9006849_3 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 579.0
TH1_k127_9006849_30 - - - - 0.0000000000000000000000000000002458 134.0
TH1_k127_9006849_31 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000001051 115.0
TH1_k127_9006849_32 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000001195 110.0
TH1_k127_9006849_33 Belongs to the UPF0235 family K09131 - - 0.0000000000000006047 81.0
TH1_k127_9006849_34 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002945 68.0
TH1_k127_9006849_36 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000007952 59.0
TH1_k127_9006849_37 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000001004 57.0
TH1_k127_9006849_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 553.0
TH1_k127_9006849_5 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 538.0
TH1_k127_9006849_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 516.0
TH1_k127_9006849_7 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 496.0
TH1_k127_9006849_8 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 394.0
TH1_k127_9006849_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 379.0
TH1_k127_9010279_0 Elongation factor SelB, winged helix K03833 - - 3.491e-218 696.0
TH1_k127_9010279_1 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 5.714e-210 682.0
TH1_k127_9010279_10 sulfur carrier activity - - - 0.00000000000000000000000000000000003773 136.0
TH1_k127_9010279_11 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000001411 133.0
TH1_k127_9010279_12 Protein of unknown function (DUF1648) - - - 0.00000000000000000003389 98.0
TH1_k127_9010279_13 Short C-terminal domain K08982 - - 0.000000000002467 70.0
TH1_k127_9010279_14 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0003438 43.0
TH1_k127_9010279_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 547.0
TH1_k127_9010279_3 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 323.0
TH1_k127_9010279_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009152 276.0
TH1_k127_9010279_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000006888 256.0
TH1_k127_9010279_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000829 195.0
TH1_k127_9010279_7 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000006436 192.0
TH1_k127_9010279_8 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000002228 172.0
TH1_k127_9010279_9 PFAM PHP domain - - - 0.00000000000000000000000000000000001375 143.0
TH1_k127_9071819_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 1.173e-234 741.0
TH1_k127_9071819_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 316.0
TH1_k127_9071819_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000001829 218.0
TH1_k127_9071819_3 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000000001149 179.0
TH1_k127_9071819_4 sequence-specific DNA binding - - - 0.000000000000000000008811 104.0
TH1_k127_9071819_5 PFAM aldo keto reductase K07079 - - 0.000002042 53.0
TH1_k127_9080313_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1247.0
TH1_k127_9080313_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.034e-294 925.0
TH1_k127_9080313_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 305.0
TH1_k127_9080313_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000004214 225.0
TH1_k127_9080313_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000004757 213.0
TH1_k127_9080313_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000001559 224.0
TH1_k127_9080313_6 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000000000000003458 198.0
TH1_k127_9080313_7 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000008973 198.0
TH1_k127_9080313_8 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000002493 171.0
TH1_k127_9080313_9 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000001222 141.0
TH1_k127_9113732_0 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 320.0
TH1_k127_9113732_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 300.0
TH1_k127_9113732_2 Protein of unknown function (DUF1460) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001131 242.0
TH1_k127_9113732_3 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000003529 207.0
TH1_k127_9113732_4 Thioredoxin-like - - - 0.0000000000000000000000000000002297 129.0
TH1_k127_9113732_5 COG0457 FOG TPR repeat - - - 0.000000000000000000000001145 118.0
TH1_k127_9113732_6 Protein of unknown function (DUF2845) - - - 0.000000000000000003937 89.0
TH1_k127_9113732_7 Trypsin domain PDZ domain protein - - - 0.00001677 57.0
TH1_k127_9286193_0 Belongs to the peptidase S16 family - - - 2.876e-242 773.0
TH1_k127_9286193_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 548.0
TH1_k127_9286193_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 496.0
TH1_k127_9286193_3 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 334.0
TH1_k127_9286193_4 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 329.0
TH1_k127_9286193_5 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001309 283.0
TH1_k127_9286193_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000002702 203.0
TH1_k127_9286193_7 exonuclease K07502 - - 0.00006711 46.0
TH1_k127_9340932_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 3.672e-261 811.0
TH1_k127_9340932_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.239e-226 723.0
TH1_k127_9340932_2 PFAM Major Facilitator Superfamily K08177 - - 5.727e-213 668.0
TH1_k127_9340932_3 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 398.0
TH1_k127_989379_0 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 473.0
TH1_k127_989379_1 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 411.0
TH1_k127_99303_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 6.962e-237 744.0
TH1_k127_99303_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 6.056e-212 673.0
TH1_k127_99303_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000007796 57.0
TH1_k127_99303_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0003204 50.0